pre-miRNA Information
pre-miRNA hsa-mir-4524a   
Genomic Coordinates chr17: 69099564 - 69099632
Description Homo sapiens miR-4524a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4524a-5p
Sequence 6| AUAGCAGCAUGAACCUGUCUCA |27
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1322445998 8 dbSNP
rs1350790266 13 dbSNP
rs1263495678 21 dbSNP
Putative Targets

Gene Information
Gene Symbol KANK1   
Synonyms ANKRD15, CPSQ2, KANK
Description KN motif and ankyrin repeat domains 1
Transcript NM_015158   
Other Transcripts NM_153186   
Expression
Putative miRNA Targets on KANK1
3'UTR of KANK1
(miRNA target sites are highlighted)
>KANK1|NM_015158|3'UTR
   1 TTGTATGCAAATAGCCCTTTATTTACATGCCACTATTAAGCTGCTAATTGTTCCTGTTGGGGTGACAGATACTGAATGTA
  81 TACGTATTGTGCCTGAGCTCACCAGCAAACAGAAGCATCAAGCCCAGGGGTAAAGGCTGAAGCTTTCACAGTGCAGAGAC
 161 TGCTAGCCTGGGCACACACACCTCCTTTCTGGCCGTCTTCTGTGTAGGGCACACTTTAACCCAGTCTCTGTTGCTGTTGA
 241 GTCTCTGCTCCGTTTTGTACAGTCACAGGGAATTCTGATCTGAAGGGGCACCTTCTGTTCACTCCCACAAAGTGGTGTCT
 321 GGTTCTCACTGAGACGTTTTAAGATTTTTCCACAAATATTTATATGTACTAAATGTGGAACCATTAGAAAGTTCTTCCAA
 401 AATCTCATTCCAGCATAGTTTTGGATTTTTCTTTTGTCTTATTTTAAAATAAGGAAGTCGAGATGACTTTGATCATTGGT
 481 AACTTGGGCCTGGGCCAGACAAAGTATAAAACTTACAAAAGAATATTCTCATTTGGTCTTAACTAGGTAGATGTAATATA
 561 TGACTTTTTATAAAAAGGGTATCTATATGAACTTGACACAGTATTTTCAGCTTTTGTATTCCATACTAAAGCCATGAAGA
 641 ACTACACGTAACATCATCATTTGTATTAATTGCACAACTCCAATGCTAAAGGTTGGATTGTGTTAGAGGAATCGGCTCTG
 721 TATTTGCCTCTAGAGAAACACAGTGTTCTCTTTGTATTTATGGATTCCTTTTTACCGTGTCACATTTACTTTGGTCCTCT
 801 ATGTATTTAAATGTTTGAAGTGCCTTAGACTCTTGCCATATTTTCAAAATAAAATTCCATTAAGCTCTTTTAAAAAAAAA
 881 AAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' acuCUGUCCAAGUACGACGAUa 5'
             | ||   |:| ||||||| 
Target 5' catGCCACTATTAAGCTGCTAa 3'
26 - 47 151.00 -8.60
2
miRNA  3' acucuGUCCAAGUACGACGAUa 5'
               |||  || ||:||||: 
Target 5' taaccCAGTCTC-TGTTGCTGt 3'
217 - 237 124.00 -13.10
3
miRNA  3' acucUGUCCAAGU-AC-GACGAUa 5'
              ||| || ||  | |||||| 
Target 5' tttcACA-GTGCAGAGACTGCTAg 3'
144 - 166 121.00 -9.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30134787 26 COSMIC
COSN31573142 29 COSMIC
COSN30500862 33 COSMIC
COSN30484033 35 COSMIC
COSN15305186 55 COSMIC
COSN31538131 65 COSMIC
COSN18733953 69 COSMIC
COSN31564315 73 COSMIC
COSN14397279 83 COSMIC
COSN19645474 179 COSMIC
COSN31587400 197 COSMIC
COSN31481459 532 COSMIC
COSN16128237 595 COSMIC
COSN31518951 755 COSMIC
COSN15601706 846 COSMIC
COSN32064563 859 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs753005788 3 dbSNP
rs1311094062 4 dbSNP
rs758971999 5 dbSNP
rs1367052744 6 dbSNP
rs376052597 9 dbSNP
rs1223093396 10 dbSNP
rs751126767 15 dbSNP
rs756688261 16 dbSNP
rs1212412354 17 dbSNP
rs1323258049 17 dbSNP
rs781056095 18 dbSNP
rs745501043 19 dbSNP
rs545055038 20 dbSNP
rs1181995570 21 dbSNP
rs779998877 23 dbSNP
rs1440734190 25 dbSNP
rs748305107 26 dbSNP
rs1406487431 27 dbSNP
rs768661309 28 dbSNP
rs774134555 32 dbSNP
rs1404728711 34 dbSNP
rs1482240241 35 dbSNP
rs760851394 36 dbSNP
rs776900220 38 dbSNP
rs775818908 40 dbSNP
rs147615192 43 dbSNP
rs1441254524 45 dbSNP
rs1277673469 47 dbSNP
rs1369727516 50 dbSNP
rs765380981 51 dbSNP
rs17369029 55 dbSNP
rs935474235 57 dbSNP
rs1435365100 59 dbSNP
rs186944885 60 dbSNP
rs1319787435 61 dbSNP
rs1457308231 62 dbSNP
rs1413350426 67 dbSNP
rs377271475 69 dbSNP
rs1002858852 70 dbSNP
rs1427743552 71 dbSNP
rs1055355051 75 dbSNP
rs1487393536 76 dbSNP
rs749421001 79 dbSNP
rs1218040703 83 dbSNP
rs771299795 84 dbSNP
rs11540723 85 dbSNP
rs1325557702 90 dbSNP
rs900459761 98 dbSNP
rs746228828 99 dbSNP
rs772627297 103 dbSNP
rs754394578 106 dbSNP
rs1435204616 108 dbSNP
rs965155091 111 dbSNP
rs775842441 115 dbSNP
rs1456159163 119 dbSNP
rs1361391143 120 dbSNP
rs975753628 122 dbSNP
rs1432895137 123 dbSNP
rs1004698431 127 dbSNP
rs1423336389 127 dbSNP
rs1450207899 129 dbSNP
rs1247540256 130 dbSNP
rs957949056 132 dbSNP
rs757733238 139 dbSNP
rs1359377534 144 dbSNP
rs1479295986 146 dbSNP
rs989151126 148 dbSNP
rs760275855 153 dbSNP
rs1274705506 155 dbSNP
rs963448230 156 dbSNP
rs945087073 157 dbSNP
rs973440847 159 dbSNP
rs528917957 165 dbSNP
rs1340865086 167 dbSNP
rs868051537 169 dbSNP
rs944505803 170 dbSNP
rs1023638340 171 dbSNP
rs1303874946 172 dbSNP
rs1465871228 173 dbSNP
rs928133029 175 dbSNP
rs1310473341 177 dbSNP
rs779438413 178 dbSNP
rs3739586 179 dbSNP
rs1186831974 180 dbSNP
rs568805906 182 dbSNP
rs11540722 184 dbSNP
rs1425565620 185 dbSNP
rs537949800 186 dbSNP
rs899382256 192 dbSNP
rs551493493 195 dbSNP
rs115434462 196 dbSNP
rs1247546153 198 dbSNP
rs1321741957 199 dbSNP
rs886550018 200 dbSNP
rs913019490 202 dbSNP
rs192429906 203 dbSNP
rs775879251 210 dbSNP
rs1018960708 212 dbSNP
rs1287093762 225 dbSNP
rs554146127 227 dbSNP
rs1410827257 232 dbSNP
rs776372878 235 dbSNP
rs1199031452 237 dbSNP
rs1258702844 238 dbSNP
rs551382205 242 dbSNP
rs1164144600 246 dbSNP
rs772134634 248 dbSNP
rs780143937 249 dbSNP
rs1169087274 251 dbSNP
rs1181751135 252 dbSNP
rs557571019 253 dbSNP
rs751710382 253 dbSNP
rs1211220373 260 dbSNP
rs931615402 262 dbSNP
rs1264407025 265 dbSNP
rs1051708258 267 dbSNP
rs1241970729 267 dbSNP
rs16923293 268 dbSNP
rs1290684151 270 dbSNP
rs1229413484 273 dbSNP
rs796957369 274 dbSNP
rs1350202496 278 dbSNP
rs556288636 281 dbSNP
rs1388793485 288 dbSNP
rs1391707521 293 dbSNP
rs1360836918 300 dbSNP
rs1293082720 306 dbSNP
rs1456397614 307 dbSNP
rs989166327 309 dbSNP
rs571347439 312 dbSNP
rs1472157685 315 dbSNP
rs966339636 316 dbSNP
rs1036194827 324 dbSNP
rs1396512411 325 dbSNP
rs576343153 328 dbSNP
rs1266229817 329 dbSNP
rs545136309 332 dbSNP
rs1242476482 335 dbSNP
rs747229421 336 dbSNP
rs565032621 337 dbSNP
rs1235880260 342 dbSNP
rs1331903617 345 dbSNP
rs1300776549 352 dbSNP
rs1447692095 357 dbSNP
rs1024111882 363 dbSNP
rs1390871327 365 dbSNP
rs1231372945 369 dbSNP
rs969434777 375 dbSNP
rs1258081358 377 dbSNP
rs1333426628 378 dbSNP
rs74712379 382 dbSNP
rs920884540 390 dbSNP
rs930892233 391 dbSNP
rs1035309077 398 dbSNP
rs1376731170 399 dbSNP
rs1196250404 401 dbSNP
rs1236956958 406 dbSNP
rs1047938054 412 dbSNP
rs956946076 413 dbSNP
rs886460136 416 dbSNP
rs944669101 419 dbSNP
rs988310762 420 dbSNP
rs1282686681 427 dbSNP
rs1464895234 427 dbSNP
rs1202558826 431 dbSNP
rs915415335 432 dbSNP
rs968156208 434 dbSNP
rs1432195138 439 dbSNP
rs1255659340 442 dbSNP
rs1232416067 443 dbSNP
rs900575091 447 dbSNP
rs1298500898 454 dbSNP
rs978551660 455 dbSNP
rs1324625172 457 dbSNP
rs1379121069 458 dbSNP
rs764974097 460 dbSNP
rs1028137206 461 dbSNP
rs1330576518 462 dbSNP
rs1401188825 467 dbSNP
rs1170562909 472 dbSNP
rs1397949073 475 dbSNP
rs1390398161 477 dbSNP
rs1448908535 478 dbSNP
rs541211577 479 dbSNP
rs931693629 484 dbSNP
rs1051857882 486 dbSNP
rs1240887312 486 dbSNP
rs1190169781 487 dbSNP
rs911850476 488 dbSNP
rs1255956867 489 dbSNP
rs940590780 493 dbSNP
rs1275543336 496 dbSNP
rs1227786772 498 dbSNP
rs1036245905 502 dbSNP
rs1303735767 506 dbSNP
rs899011236 508 dbSNP
rs1448722409 510 dbSNP
rs1339782147 511 dbSNP
rs1313148271 516 dbSNP
rs995056395 517 dbSNP
rs1218475877 518 dbSNP
rs750299151 522 dbSNP
rs1020862713 523 dbSNP
rs1370801624 523 dbSNP
rs768629472 530 dbSNP
rs1427293406 531 dbSNP
rs981741265 537 dbSNP
rs1045179758 539 dbSNP
rs1473443879 540 dbSNP
rs537056785 544 dbSNP
rs1035217109 547 dbSNP
rs369075656 549 dbSNP
rs959150551 550 dbSNP
rs1252844900 558 dbSNP
rs1204652309 561 dbSNP
rs1436261411 561 dbSNP
rs184568828 565 dbSNP
rs1355561892 566 dbSNP
rs1291296202 573 dbSNP
rs1230027228 574 dbSNP
rs1350839603 574 dbSNP
rs1003581900 579 dbSNP
rs758242670 580 dbSNP
rs930788818 584 dbSNP
rs1323726936 585 dbSNP
rs956669286 586 dbSNP
rs1009785701 587 dbSNP
rs1394419824 588 dbSNP
rs1189095703 600 dbSNP
rs1269092024 602 dbSNP
rs766377616 606 dbSNP
rs1169609413 614 dbSNP
rs530348335 617 dbSNP
rs1467070561 619 dbSNP
rs1222417419 622 dbSNP
rs1451059975 623 dbSNP
rs1171353966 625 dbSNP
rs1349345313 627 dbSNP
rs1271229923 629 dbSNP
rs550402438 640 dbSNP
rs1040348164 646 dbSNP
rs1329746556 646 dbSNP
rs879325816 648 dbSNP
rs145928526 649 dbSNP
rs893660933 653 dbSNP
rs1435163782 654 dbSNP
rs921736215 655 dbSNP
rs1020892432 664 dbSNP
rs1160677516 665 dbSNP
rs1459329359 667 dbSNP
rs902424241 674 dbSNP
rs953244676 675 dbSNP
rs987198209 678 dbSNP
rs751411134 679 dbSNP
rs1276656385 684 dbSNP
rs1453968171 688 dbSNP
rs940310251 689 dbSNP
rs531331086 700 dbSNP
rs1465340480 701 dbSNP
rs1267356335 702 dbSNP
rs1213404204 703 dbSNP
rs1036299716 707 dbSNP
rs1034672904 712 dbSNP
rs1278936381 713 dbSNP
rs1218320619 714 dbSNP
rs959413085 715 dbSNP
rs920493733 716 dbSNP
rs1366573546 717 dbSNP
rs1435183562 717 dbSNP
rs113428617 720 dbSNP
rs1027778411 722 dbSNP
rs1361302262 722 dbSNP
rs952220722 723 dbSNP
rs1177210911 727 dbSNP
rs983575077 728 dbSNP
rs1393492761 730 dbSNP
rs1218667127 738 dbSNP
rs1170566177 740 dbSNP
rs930524381 743 dbSNP
rs1260988051 744 dbSNP
rs1045294479 746 dbSNP
rs1484179127 749 dbSNP
rs10915 762 dbSNP
rs1192508534 766 dbSNP
rs1345381073 769 dbSNP
rs1276252805 771 dbSNP
rs1228526389 774 dbSNP
rs939436933 776 dbSNP
rs1056442431 777 dbSNP
rs571349968 778 dbSNP
rs976516064 784 dbSNP
rs751186063 785 dbSNP
rs1303856717 793 dbSNP
rs1414473361 795 dbSNP
rs921967232 800 dbSNP
rs1430525139 801 dbSNP
rs541904613 802 dbSNP
rs1425546675 804 dbSNP
rs749530860 804 dbSNP
rs1186966729 812 dbSNP
rs1414443418 812 dbSNP
rs1009503220 816 dbSNP
rs1022529924 818 dbSNP
rs1253562654 819 dbSNP
rs76830912 821 dbSNP
rs1413058881 823 dbSNP
rs1403552470 825 dbSNP
rs1166922284 828 dbSNP
rs904094421 829 dbSNP
rs547300342 833 dbSNP
rs1223117167 834 dbSNP
rs1419278316 839 dbSNP
rs1296637959 846 dbSNP
rs997062439 859 dbSNP
rs1313988022 860 dbSNP
rs566918441 861 dbSNP
rs946567732 861 dbSNP
rs1290567773 867 dbSNP
rs1410725690 868 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' acucuGUCCAAGUACGACGAUa 5'
               ||   |:| ||||||| 
Target 5' ----cCACUAUUAAGCUGCUAa 3'
1 - 18
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23189.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' acucuGUCCAAGUACGACGAUa 5'
               ||   |:| ||||||| 
Target 5' ----cCACUAUUAAGCUGCUAa 3'
1 - 18
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000382303.1 | 3UTR | CCACUAUUAAGCUGCUAAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000382303.1 | 3UTR | CCACUAUUAAGCUGCUAAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
180 hsa-miR-4524a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055251 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT055826 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT060573 CCND1 cyclin D1 2 2
MIRT061013 C1ORF21 chromosome 1 open reading frame 21 2 6
MIRT064694 CCND2 cyclin D2 2 4
MIRT075268 SNTB2 syntrophin beta 2 2 4
MIRT079668 NAPG NSF attachment protein gamma 2 12
MIRT081651 CCNE1 cyclin E1 2 4
MIRT082996 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT083463 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 2 4
MIRT085755 RIF1 replication timing regulatory factor 1 2 2
MIRT086022 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 2
MIRT087431 ZNRF3 zinc and ring finger 3 2 2
MIRT088786 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT089221 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT093696 PI4K2B phosphatidylinositol 4-kinase type 2 beta 2 6
MIRT095090 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT096249 CANX calnexin 2 2
MIRT100215 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT100746 VEGFA vascular endothelial growth factor A 2 12
MIRT100904 CD2AP CD2 associated protein 2 2
MIRT102647 UBN2 ubinuclein 2 2 10
MIRT103882 FOXK1 forkhead box K1 2 2
MIRT104246 DMTF1 cyclin D binding myb like transcription factor 1 2 2
MIRT106310 ZFHX4 zinc finger homeobox 4 2 6
MIRT107696 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT114943 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT117671 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT133799 SKI SKI proto-oncogene 2 2
MIRT140167 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT142279 DCTN5 dynactin subunit 5 2 8
MIRT143288 N4BP1 NEDD4 binding protein 1 2 2
MIRT165939 CREBRF CREB3 regulatory factor 2 2
MIRT175251 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT186381 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT191470 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A 2 2
MIRT196480 TAOK1 TAO kinase 1 2 2
MIRT201470 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT204615 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT204646 MOB4 MOB family member 4, phocein 2 8
MIRT204749 BZW1 basic leucine zipper and W2 domains 1 2 12
MIRT206031 NUP50 nucleoporin 50 2 6
MIRT211196 FGF2 fibroblast growth factor 2 2 4
MIRT229353 ZNF449 zinc finger protein 449 2 2
MIRT247138 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT249461 ZNF691 zinc finger protein 691 2 4
MIRT256314 CDC42SE2 CDC42 small effector 2 2 2
MIRT258419 WIPI2 WD repeat domain, phosphoinositide interacting 2 2 2
MIRT265083 CHEK1 checkpoint kinase 1 2 2
MIRT270561 SETD1B SET domain containing 1B 2 2
MIRT274749 RAB3IP RAB3A interacting protein 2 2
MIRT277515 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT289642 CBX2 chromobox 2 2 2
MIRT301001 MTMR3 myotubularin related protein 3 2 2
MIRT307149 CTDSPL CTD small phosphatase like 2 4
MIRT309021 USP53 ubiquitin specific peptidase 53 2 2
MIRT314100 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 8
MIRT319338 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT320619 ZNRF2 zinc and ring finger 2 2 2
MIRT324285 LURAP1L leucine rich adaptor protein 1 like 2 2
MIRT446498 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT448437 TLL1 tolloid like 1 2 2
MIRT461537 ACTR3B ARP3 actin related protein 3 homolog B 2 2
MIRT463162 ZNF367 zinc finger protein 367 2 10
MIRT463493 ZC3H10 zinc finger CCCH-type containing 10 2 2
MIRT465154 TSC22D2 TSC22 domain family member 2 2 2
MIRT466418 TFAP2A transcription factor AP-2 alpha 2 8
MIRT468278 SFT2D2 SFT2 domain containing 2 2 2
MIRT469399 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT471941 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT473688 MAPK8 mitogen-activated protein kinase 8 2 4
MIRT479618 CDC25A cell division cycle 25A 2 2
MIRT482098 AKT3 AKT serine/threonine kinase 3 2 4
MIRT483995 ATAD5 ATPase family, AAA domain containing 5 2 12
MIRT485205 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 8
MIRT498763 C3orf38 chromosome 3 open reading frame 38 2 8
MIRT498961 ORC4 origin recognition complex subunit 4 2 8
MIRT499440 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT500080 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 8
MIRT500305 ZNF622 zinc finger protein 622 2 8
MIRT500410 ZMAT3 zinc finger matrin-type 3 2 8
MIRT500789 TLK1 tousled like kinase 1 2 6
MIRT500930 SRPR SRP receptor alpha subunit 2 6
MIRT500943 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 8
MIRT501068 SMAD7 SMAD family member 7 2 8
MIRT501711 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT502627 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT502910 CDCA4 cell division cycle associated 4 2 8
MIRT502935 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504531 ZNF620 zinc finger protein 620 2 6
MIRT505106 YTHDC1 YTH domain containing 1 2 6
MIRT505337 TMEM245 transmembrane protein 245 2 6
MIRT505383 TMEM100 transmembrane protein 100 2 2
MIRT505678 SESTD1 SEC14 and spectrin domain containing 1 2 6
MIRT506157 PLAG1 PLAG1 zinc finger 2 8
MIRT506183 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 6
MIRT506475 MYO5A myosin VA 2 6
MIRT506826 KIF23 kinesin family member 23 2 6
MIRT507160 GAS2L3 growth arrest specific 2 like 3 2 2
MIRT507511 DYNLL2 dynein light chain LC8-type 2 2 4
MIRT507845 CCNE2 cyclin E2 2 6
MIRT510403 ZNF507 zinc finger protein 507 2 2
MIRT518078 TRIM35 tripartite motif containing 35 2 2
MIRT518982 NNT nicotinamide nucleotide transhydrogenase 2 4
MIRT521045 SLC2A3 solute carrier family 2 member 3 2 4
MIRT521190 SBNO1 strawberry notch homolog 1 2 6
MIRT522088 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 4
MIRT524846 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT527787 TMEM44 transmembrane protein 44 2 4
MIRT537803 EFNB2 ephrin B2 2 4
MIRT540830 GNAT1 G protein subunit alpha transducin 1 2 4
MIRT541140 PISD phosphatidylserine decarboxylase 2 2
MIRT541419 CBX4 chromobox 4 2 2
MIRT543517 PRSS21 protease, serine 21 2 2
MIRT543824 GSG1 germ cell associated 1 2 2
MIRT544959 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT545179 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 4
MIRT545335 CCDC83 coiled-coil domain containing 83 2 2
MIRT545518 RSL24D1 ribosomal L24 domain containing 1 2 2
MIRT545670 DECR1 2,4-dienoyl-CoA reductase 1 2 2
MIRT545931 ZBTB44 zinc finger and BTB domain containing 44 2 4
MIRT546102 USP48 ubiquitin specific peptidase 48 2 4
MIRT546598 SALL1 spalt like transcription factor 1 2 4
MIRT546626 RTN4 reticulon 4 2 2
MIRT547651 KPNA3 karyopherin subunit alpha 3 2 2
MIRT547987 HCFC2 host cell factor C2 2 4
MIRT548717 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT548931 CDK17 cyclin dependent kinase 17 2 2
MIRT549067 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT549266 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT550460 OSCAR osteoclast associated, immunoglobulin-like receptor 2 4
MIRT550806 FAM229B family with sequence similarity 229 member B 2 2
MIRT552024 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552334 ZNF704 zinc finger protein 704 2 2
MIRT552732 YRDC yrdC N6-threonylcarbamoyltransferase domain containing 2 2
MIRT553795 SZRD1 SUZ RNA binding domain containing 1 2 4
MIRT554694 RNF149 ring finger protein 149 2 2
MIRT555133 PTPRD protein tyrosine phosphatase, receptor type D 2 2
MIRT555264 PRDM4 PR/SET domain 4 2 2
MIRT556848 KANK1 KN motif and ankyrin repeat domains 1 2 4
MIRT557474 GPR27 G protein-coupled receptor 27 2 4
MIRT558018 EXT1 exostosin glycosyltransferase 1 2 2
MIRT558498 CYP26B1 cytochrome P450 family 26 subfamily B member 1 2 4
MIRT558579 CREBL2 cAMP responsive element binding protein like 2 2 4
MIRT558610 COX6B1 cytochrome c oxidase subunit 6B1 2 4
MIRT558650 CNKSR3 CNKSR family member 3 2 2
MIRT558986 CA8 carbonic anhydrase 8 2 2
MIRT559141 BTN3A3 butyrophilin subfamily 3 member A3 2 2
MIRT559327 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT562021 LANCL1 LanC like 1 2 2
MIRT562869 KIAA1456 KIAA1456 2 2
MIRT563074 SLC25A12 solute carrier family 25 member 12 2 2
MIRT563496 DLGAP3 DLG associated protein 3 2 2
MIRT563890 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564311 CCNT1 cyclin T1 2 2
MIRT564942 XKR7 XK related 7 2 2
MIRT564979 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT565423 TEF TEF, PAR bZIP transcription factor 2 2
MIRT566824 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 2
MIRT571961 KIF5B kinesin family member 5B 2 2
MIRT575877 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2 3
MIRT576523 Txlna taxilin alpha 2 2
MIRT614693 TRAK1 trafficking kinesin protein 1 2 2
MIRT616065 ZC3H14 zinc finger CCCH-type containing 14 2 2
MIRT618838 ASAH2B N-acylsphingosine amidohydrolase 2B 2 2
MIRT624626 ATXN2 ataxin 2 2 2
MIRT624652 ASAH2 N-acylsphingosine amidohydrolase 2 2 2
MIRT640314 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT659248 CUL3 cullin 3 2 2
MIRT680972 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT682261 RS1 retinoschisin 1 2 2
MIRT682505 GLP2R glucagon like peptide 2 receptor 2 2
MIRT693904 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT699214 SLCO3A1 solute carrier organic anion transporter family member 3A1 2 2
MIRT699373 SLC30A6 solute carrier family 30 member 6 2 2
MIRT699451 SLC16A9 solute carrier family 16 member 9 2 2
MIRT701230 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT702849 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT706163 CASK calcium/calmodulin dependent serine protein kinase 2 3
MIRT718990 UTP15 UTP15, small subunit processome component 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4524a-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-4524a-5p Cetuximab resistant tissue (colorectal carcinoma)

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