miRTarBase - #MIRT557081


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pre-miRNA Information
pre-miRNA hsa-mir-4653   
Genomic Coordinates chr7: 101159473 - 101159555
Description Homo sapiens miR-4653 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4653-5p
Sequence 10| UCUCUGAGCAAGGCUUAACACC |31
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs566953516 2 dbSNP
rs1307365749 4 dbSNP
rs1226652366 6 dbSNP
rs1216592229 12 dbSNP
rs1283699546 15 dbSNP
rs934609749 20 dbSNP
rs1377199291 21 dbSNP
rs1282994534 22 dbSNP
Putative Targets

Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B8DF7B miR-4653 Predictive Biomarker (PRD) Transcriptomic Data . . . .
Gene Information
Gene Symbol HOXB3   
Synonyms HOX2, HOX2G, Hox-2.7
Description homeobox B3
Transcript NM_002146   
Expression
Putative miRNA Targets on HOXB3
3'UTR of HOXB3
(miRNA target sites are highlighted)		 
>HOXB3|NM_002146|3'UTR
   1 TGGGAAAGGGCGAACGAGGATTAGGGGATGGGGAGGAAGAGAGAGACTGTGGAGCTCTGGGGGGCAACCTGGAGGTCTGA
  81 AAAGAGGAGCCAGAGAAGGTGGTACCCAGGCTTCCTGGTCAGAACCGGCCTGGAGCTCCTTCCCTTCCCCCTGGCCTGAG
 161 AGGTTGCTTTTAAGTCTTCCACCCCTTGTTCCATCTGCCTGCCAACCCATCGGAAAGGAATCCACATCATATTGGAGATG
 241 ACCCCATCAACCCCAGGGCTCCAGCACTACCAAGTTGGAATTCCACGCCCGGGAGTGGGGTAGAGGAAGACGAGACAGGA
 321 CGAGGCAGAAAAGCACATTTTAAAAACCAGACAAGATGGCTAGGCCATCACCAACCAACGGACTTACCTTACATCTTTGT
 401 AGGTAATTCCCCCCAAATCTTGATTTTTTTTTTTCCTCAATTATCCTTTAAAAAATAAGAAAACACATTTCAAACCCAAA
 481 AGGCACAAAACACGTTCCCTTCCAACTTTCCCAAAACCTCAAATTTGTTCCCATTTGAGGTTTATTGAGGTACACTTCTA
 561 GCCCCCGGTTTTTCTGCTCTAGAACATTCATATCTATACATCCCACCCCCATCAATTACAGTTTTTAGAGGGCTCAGGGA
 641 TGGTGAGAGATCCTGAAAGAGCTGCCTATATTATAAATTATATACATTTTTTTTTAAGGAAAAGTGTGGAGGCTAGGGCA
 721 GGCAGGTTGTTAGGACTGAAGGTTTGCCCATTCTGCTGCCTCCATCTCAGCTCCAGCTCCATCCCCCTCTCCACAGAAAG
 801 CAGTTGGTGACACGAGGTTCTATACTTTTCTTCTGTTGCTCTCTTGACTTAACGTGAAAACAGGGTATATTTGAACAAAC
 881 TGTCCCAGGCAGGGGCTGGGCAGGGCCTGTGTGCCTTGCTCAGCCTCCTGACAGGACACTTTTGTTGCACTTAGAATTTA
 961 CATTTTAATGGATGTAAAAACAACTGTGAGAGATGTCTGGGCCTGCAGAAGTCCAGCATTGCTCAAAAAAGCGTGTGTTC
1041 TAGTGAACATTTTCATATATATTTATTGGTTATAGCCTGTTAAAATATTTTCTTTTTTGTATTATTTATCCCCCTACATT
1121 ATGTATTTATATGAGGGAAAAAAAGGAAAAAATTGTACTTTTTTAGTATTTACCTGTTACAAAGGACATTGTGTTTCCTG
1201 TCATGTAAAACCAGCTATTTTAGTTACTATTGTACTCTAGAAAAGAGCTGTAGATTTATGTTAAACTCGTACTTACGAAC
1281 AATTGTAATTAGTTCTAAAAGGCATGAACTCAGCTCCTAATCGTCACTGTATAGTCCTGAATTTGTAGAACTAGAGTTAA
1361 TTCCCTCTTGGAACTTTCTTTGTTCTTCAGTAGTTACTTTTTTCCTTACCTAAAAGGGTTGTCTGTCAAACAATTCTTGA
1441 ATAAACTTTCTGTTATCAATTTTAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccacAAU-UCGGAA------CGAGUCUCu 5'
              ||| ||::||      ||||||:| 
Target 5' tcaaTTACAGTTTTTAGAGGGCTCAGGGa 3'
 612 - 640 140.00 -15.80
2 
miRNA  3' ccACAAUUCGGAACGAGUCucu 5'
            || |: |||||||||||   
Target 5' ccTG-TGTGCCTTGCTCAGcct 3'
 906 - 926 135.00 -20.92
3 
miRNA  3' ccaCAAUUCGGAACGAGUCUcu 5'
             ||  ||| ||||||| |  
Target 5' gaaGTCCAGCATTGCTCAAAaa 3'
 1008 - 1029 119.00 -10.56
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30179564 11 COSMIC
COSN30475441 16 COSMIC
COSN30491505 19 COSMIC
COSN7437034 19 COSMIC
COSN9669966 28 COSMIC
COSN13728812 31 COSMIC
COSN18715931 36 COSMIC
COSN30160413 43 COSMIC
COSN30477647 45 COSMIC
COSN31541568 58 COSMIC
COSN30461174 86 COSMIC
COSN30170136 98 COSMIC
COSN30515095 111 COSMIC
COSN20114097 424 COSMIC
COSN14630884 455 COSMIC
COSN26635835 589 COSMIC
COSN26564109 599 COSMIC
COSN28956536 615 COSMIC
COSN20114095 686 COSMIC
COSN18723787 879 COSMIC
COSN20114089 879 COSMIC
COSN31601274 887 COSMIC
COSN32056845 894 COSMIC
COSN8603311 898 COSMIC
COSN31562799 932 COSMIC
COSN31545759 1024 COSMIC
COSN31550131 1101 COSMIC
COSN19536903 1112 COSMIC
COSN31532054 1114 COSMIC
COSN31483383 1155 COSMIC
COSN30161894 1157 COSMIC
COSN21140673 1245 COSMIC
COSN31522093 1335 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs746944609 1 dbSNP
rs1206525910 4 dbSNP
rs1235699910 5 dbSNP
rs1472156950 7 dbSNP
rs1056188773 8 dbSNP
rs375556391 10 dbSNP
rs565883037 11 dbSNP
rs1243361829 12 dbSNP
rs758376060 13 dbSNP
rs765540492 15 dbSNP
rs1210762337 18 dbSNP
rs1390378778 18 dbSNP
rs1393687893 22 dbSNP
rs1489278662 26 dbSNP
rs768944960 28 dbSNP
rs1335283439 30 dbSNP
rs370619296 31 dbSNP
rs754187524 32 dbSNP
rs766683458 33 dbSNP
rs1443015898 34 dbSNP
rs371125954 36 dbSNP
rs750871349 39 dbSNP
rs768137786 40 dbSNP
rs1227998281 41 dbSNP
rs1248466995 42 dbSNP
rs762436735 43 dbSNP
rs774996867 45 dbSNP
rs769371734 46 dbSNP
rs1323947743 47 dbSNP
rs759220924 47 dbSNP
rs373134555 48 dbSNP
rs1219908721 49 dbSNP
rs1361317902 50 dbSNP
rs746864099 51 dbSNP
rs1204531836 52 dbSNP
rs941273345 52 dbSNP
rs1007692405 54 dbSNP
rs1022565080 55 dbSNP
rs776869808 55 dbSNP
rs909768134 58 dbSNP
rs554812390 59 dbSNP
rs1481594498 60 dbSNP
rs983025763 61 dbSNP
rs1402036534 64 dbSNP
rs1011546984 68 dbSNP
rs771093471 69 dbSNP
rs929803193 71 dbSNP
rs1352813060 72 dbSNP
rs1052416048 73 dbSNP
rs939455809 74 dbSNP
rs1218253121 75 dbSNP
rs1347647920 76 dbSNP
rs142560479 78 dbSNP
rs1045138094 85 dbSNP
rs1370565696 87 dbSNP
rs1344128971 94 dbSNP
rs760531631 99 dbSNP
rs1295224969 101 dbSNP
rs1215075642 103 dbSNP
rs1481769265 104 dbSNP
rs546829890 104 dbSNP
rs139598264 106 dbSNP
rs1269079495 110 dbSNP
rs563553916 113 dbSNP
rs541093093 114 dbSNP
rs929866500 116 dbSNP
rs185335892 117 dbSNP
rs1355490518 118 dbSNP
rs561419370 125 dbSNP
rs979043590 126 dbSNP
rs1303851877 127 dbSNP
rs756683710 127 dbSNP
rs1463759344 128 dbSNP
rs1330280752 132 dbSNP
rs1227940789 133 dbSNP
rs1020510174 138 dbSNP
rs1010831791 139 dbSNP
rs1339986234 142 dbSNP
rs1226934920 143 dbSNP
rs1017983004 144 dbSNP
rs1165068325 147 dbSNP
rs1361042316 149 dbSNP
rs1207676122 150 dbSNP
rs985592149 151 dbSNP
rs953585511 152 dbSNP
rs1195807070 155 dbSNP
rs541690703 160 dbSNP
rs1422726986 162 dbSNP
rs960219799 163 dbSNP
rs1022873769 166 dbSNP
rs1246666847 167 dbSNP
rs1035205721 173 dbSNP
rs1003244570 176 dbSNP
rs1164852905 180 dbSNP
rs1387149658 182 dbSNP
rs1411613628 184 dbSNP
rs572159653 185 dbSNP
rs1178894629 192 dbSNP
rs892707707 198 dbSNP
rs748021615 202 dbSNP
rs1162862858 207 dbSNP
rs1385990113 208 dbSNP
rs1031041837 211 dbSNP
rs904901725 212 dbSNP
rs1044717431 214 dbSNP
rs565004609 226 dbSNP
rs182653717 229 dbSNP
rs1232121934 232 dbSNP
rs1196474142 233 dbSNP
rs1242019738 246 dbSNP
rs1264444559 246 dbSNP
rs1003551985 248 dbSNP
rs1207196695 251 dbSNP
rs1266622123 258 dbSNP
rs906492056 261 dbSNP
rs1184733716 269 dbSNP
rs1005137613 270 dbSNP
rs1456647291 273 dbSNP
rs948103141 274 dbSNP
rs1214469640 275 dbSNP
rs1321182021 277 dbSNP
rs1310588295 279 dbSNP
rs1225975944 284 dbSNP
rs1374633766 285 dbSNP
rs1456544448 290 dbSNP
rs1309010219 291 dbSNP
rs888382888 293 dbSNP
rs1404294402 295 dbSNP
rs1048703305 297 dbSNP
rs929945544 298 dbSNP
rs762437378 299 dbSNP
rs4793578 302 dbSNP
rs1286124911 303 dbSNP
rs1040903263 311 dbSNP
rs943725862 312 dbSNP
rs575967101 315 dbSNP
rs147380384 324 dbSNP
rs1200452008 333 dbSNP
rs536508065 333 dbSNP
rs1251316959 335 dbSNP
rs768247725 340 dbSNP
rs1421005795 341 dbSNP
rs1041567198 347 dbSNP
rs573857895 349 dbSNP
rs1176902747 357 dbSNP
rs1360756485 359 dbSNP
rs1464480300 365 dbSNP
rs763393263 369 dbSNP
rs990046275 378 dbSNP
rs1401241165 387 dbSNP
rs1411172691 391 dbSNP
rs942755752 392 dbSNP
rs1379588960 393 dbSNP
rs911276305 393 dbSNP
rs1176587071 399 dbSNP
rs956824244 403 dbSNP
rs765976002 413 dbSNP
rs968675738 416 dbSNP
rs913501207 419 dbSNP
rs1233130289 426 dbSNP
rs1003771316 429 dbSNP
rs970729564 433 dbSNP
rs770055974 434 dbSNP
rs1201952146 435 dbSNP
rs1267265787 435 dbSNP
rs398030980 435 dbSNP
rs398079026 435 dbSNP
rs60329254 435 dbSNP
rs74432128 435 dbSNP
rs1488239525 436 dbSNP
rs1263786652 438 dbSNP
rs1217977710 439 dbSNP
rs1318095280 440 dbSNP
rs1431278598 445 dbSNP
rs1175235470 448 dbSNP
rs989056251 455 dbSNP
rs1373609112 456 dbSNP
rs553548417 464 dbSNP
rs888522383 468 dbSNP
rs1369486884 478 dbSNP
rs1405162296 485 dbSNP
rs1294973171 491 dbSNP
rs1365884917 493 dbSNP
rs1350526318 509 dbSNP
rs1048442490 510 dbSNP
rs1035854087 513 dbSNP
rs1226185176 518 dbSNP
rs1385906967 522 dbSNP
rs1001623116 525 dbSNP
rs576561600 527 dbSNP
rs969112316 529 dbSNP
rs1245243747 545 dbSNP
rs1487362158 548 dbSNP
rs1190434520 551 dbSNP
rs1451263190 555 dbSNP
rs1166702643 556 dbSNP
rs1388987502 559 dbSNP
rs1023318527 562 dbSNP
rs1430780576 563 dbSNP
rs1424786110 571 dbSNP
rs1166416629 576 dbSNP
rs1347779681 585 dbSNP
rs1040954044 589 dbSNP
rs1289820426 590 dbSNP
rs190411019 591 dbSNP
rs186023892 596 dbSNP
rs1433513072 599 dbSNP
rs910911899 602 dbSNP
rs1156756041 605 dbSNP
rs888106475 620 dbSNP
rs1287936429 624 dbSNP
rs1436444212 630 dbSNP
rs1321369600 638 dbSNP
rs1047448607 640 dbSNP
rs1175037264 670 dbSNP
rs552224861 679 dbSNP
rs1432839171 680 dbSNP
rs1466124255 681 dbSNP
rs1265502853 683 dbSNP
rs770958418 683 dbSNP
rs1247373665 686 dbSNP
rs182006296 686 dbSNP
rs1040892959 695 dbSNP
rs202201121 696 dbSNP
rs914313948 696 dbSNP
rs956875465 699 dbSNP
rs942486090 705 dbSNP
rs911320522 706 dbSNP
rs1320425198 719 dbSNP
rs538772173 722 dbSNP
rs879637093 725 dbSNP
rs947390882 726 dbSNP
rs1282507805 728 dbSNP
rs1378624051 733 dbSNP
rs377377512 743 dbSNP
rs569991912 750 dbSNP
rs1224517916 753 dbSNP
rs142780206 755 dbSNP
rs1330892426 758 dbSNP
rs960327057 763 dbSNP
rs928840504 771 dbSNP
rs11651053 772 dbSNP
rs952706916 774 dbSNP
rs1027505207 779 dbSNP
rs994183415 786 dbSNP
rs190195286 799 dbSNP
rs547991813 805 dbSNP
rs1023370667 808 dbSNP
rs1413757756 812 dbSNP
rs527914344 813 dbSNP
rs778799686 814 dbSNP
rs1310114986 817 dbSNP
rs952527737 818 dbSNP
rs138850198 820 dbSNP
rs371785759 824 dbSNP
rs1416653342 833 dbSNP
rs1008139613 834 dbSNP
rs1358613780 835 dbSNP
rs1339290156 841 dbSNP
rs779871781 851 dbSNP
rs1310030176 856 dbSNP
rs1348873626 861 dbSNP
rs889693134 864 dbSNP
rs994206000 865 dbSNP
rs901094818 868 dbSNP
rs1287484353 875 dbSNP
rs1345520604 876 dbSNP
rs201949561 878 dbSNP
rs773359604 882 dbSNP
rs386386204 883 dbSNP
rs55687167 884 dbSNP
rs200320043 885 dbSNP
rs397778262 885 dbSNP
rs75571143 885 dbSNP
rs1253458846 887 dbSNP
rs947044134 888 dbSNP
rs1019512409 889 dbSNP
rs1181098649 895 dbSNP
rs367815767 900 dbSNP
rs1247645814 901 dbSNP
rs1479230347 902 dbSNP
rs1171293098 910 dbSNP
rs1302093451 924 dbSNP
rs1464355471 925 dbSNP
rs1170569257 932 dbSNP
rs892779035 934 dbSNP
rs1376199186 942 dbSNP
rs1053290168 945 dbSNP
rs1006754928 948 dbSNP
rs889603000 954 dbSNP
rs1478235110 959 dbSNP
rs545056642 962 dbSNP
rs924127486 968 dbSNP
rs1423049426 971 dbSNP
rs982271018 985 dbSNP
rs1228412588 986 dbSNP
rs1276155889 987 dbSNP
rs1057111 990 dbSNP
rs1339533134 995 dbSNP
rs949499238 997 dbSNP
rs916823059 998 dbSNP
rs991065958 999 dbSNP
rs1197215276 1000 dbSNP
rs1043201006 1001 dbSNP
rs1246564580 1005 dbSNP
rs952836057 1010 dbSNP
rs1191114201 1011 dbSNP
rs1388376978 1016 dbSNP
rs1191539808 1019 dbSNP
rs1429233285 1031 dbSNP
rs200675771 1032 dbSNP
rs891839663 1033 dbSNP
rs1019439747 1044 dbSNP
rs1330374225 1045 dbSNP
rs555160875 1055 dbSNP
rs1299802677 1058 dbSNP
rs542306699 1059 dbSNP
rs1253386078 1063 dbSNP
rs879117267 1069 dbSNP
rs1028676102 1091 dbSNP
rs938657725 1092 dbSNP
rs1358029464 1095 dbSNP
rs928917233 1097 dbSNP
rs1289596838 1100 dbSNP
rs1465671052 1103 dbSNP
rs1211090995 1107 dbSNP
rs980310758 1112 dbSNP
rs187506341 1115 dbSNP
rs1448890510 1116 dbSNP
rs1188353362 1122 dbSNP
rs777990165 1127 dbSNP
rs879245674 1133 dbSNP
rs892820027 1134 dbSNP
rs1471932362 1135 dbSNP
rs909385277 1137 dbSNP
rs115689527 1138 dbSNP
rs1162951066 1138 dbSNP
rs1322401205 1145 dbSNP
rs952505233 1145 dbSNP
rs1025778055 1146 dbSNP
rs972436961 1147 dbSNP
rs1234564997 1148 dbSNP
rs1045470476 1153 dbSNP
rs906961907 1153 dbSNP
rs1311908788 1155 dbSNP
rs755491330 1160 dbSNP
rs1398375644 1165 dbSNP
rs367710460 1165 dbSNP
rs1242130796 1167 dbSNP
rs1283277050 1172 dbSNP
rs1330192705 1180 dbSNP
rs1210996818 1182 dbSNP
rs35764080 1186 dbSNP
rs749998188 1188 dbSNP
rs965402641 1189 dbSNP
rs1464845364 1195 dbSNP
rs1298495671 1210 dbSNP
rs72829847 1212 dbSNP
rs1399808592 1219 dbSNP
rs1168673151 1220 dbSNP
rs1006807171 1221 dbSNP
rs756800313 1229 dbSNP
rs1476224795 1230 dbSNP
rs931563731 1231 dbSNP
rs144105716 1242 dbSNP
rs1412998345 1250 dbSNP
rs1187474168 1253 dbSNP
rs1472760449 1254 dbSNP
rs1161105620 1257 dbSNP
rs1409562492 1260 dbSNP
rs557678051 1266 dbSNP
rs1452949466 1269 dbSNP
rs1303405350 1271 dbSNP
rs1422512431 1276 dbSNP
rs1253138470 1277 dbSNP
rs972701472 1282 dbSNP
rs1179596666 1285 dbSNP
rs1021475221 1289 dbSNP
rs1350742598 1292 dbSNP
rs1011785381 1294 dbSNP
rs1286844435 1295 dbSNP
rs1316759212 1302 dbSNP
rs752164102 1304 dbSNP
rs180731656 1323 dbSNP
rs1258334720 1328 dbSNP
rs1019658654 1330 dbSNP
rs1199952370 1332 dbSNP
rs1252723134 1363 dbSNP
rs938725852 1366 dbSNP
rs542513000 1376 dbSNP
rs1180361308 1378 dbSNP
rs1249320909 1396 dbSNP
rs549463449 1399 dbSNP
rs1044667145 1401 dbSNP
rs1176651575 1404 dbSNP
rs1379321065 1406 dbSNP
rs1464055970 1417 dbSNP
rs1172480788 1419 dbSNP
rs954026775 1423 dbSNP
rs1411264304 1428 dbSNP
rs1305853364 1436 dbSNP
rs752908460 1452 dbSNP
rs1264283199 1456 dbSNP
rs531326544 1461 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 3213.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ccacaauucGGAACGAGUCucu 5'
                   ||||||||||   
Target 5' ---------CCUUGCUCAGccu 3'
 		1 - 13
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000470495.1 | 3UTR | CCUUGCUCAGCCUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
78 hsa-miR-4653-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT118186 ZNF544 zinc finger protein 544 2 2
MIRT332935 PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 2 2
MIRT442166 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT442387 CLVS2 clavesin 2 2 2
MIRT442595 SIX1 SIX homeobox 1 2 2
MIRT448014 HLA-DOA major histocompatibility complex, class II, DO alpha 2 2
MIRT448061 MMP15 matrix metallopeptidase 15 2 2
MIRT489017 C1QTNF6 C1q and TNF related 6 2 2
MIRT494456 BTG2 BTG anti-proliferation factor 2 2 2
MIRT495650 SLC35B2 solute carrier family 35 member B2 2 2
MIRT504016 ACSL6 acyl-CoA synthetase long chain family member 6 2 2
MIRT506777 KLHL15 kelch like family member 15 2 4
MIRT507229 FOXN2 forkhead box N2 2 4
MIRT512550 MFN2 mitofusin 2 2 6
MIRT512842 A1CF APOBEC1 complementation factor 2 6
MIRT513944 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT516103 GADL1 glutamate decarboxylase like 1 2 4
MIRT519831 ZFP69B ZFP69 zinc finger protein B 2 4
MIRT523210 HIST1H3E histone cluster 1 H3 family member e 2 2
MIRT525008 ACTN4 actinin alpha 4 2 6
MIRT528858 PKP1 plakophilin 1 2 2
MIRT529062 ZNF675 zinc finger protein 675 2 2
MIRT531719 TARS threonyl-tRNA synthetase 2 2
MIRT534039 STK4 serine/threonine kinase 4 2 2
MIRT543848 APIP APAF1 interacting protein 2 2
MIRT545866 ZNF264 zinc finger protein 264 2 4
MIRT556037 MXD1 MAX dimerization protein 1 2 2
MIRT557081 HOXB3 homeobox B3 2 2
MIRT561345 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT562705 ZNF415 zinc finger protein 415 2 2
MIRT563223 ZNF286A zinc finger protein 286A 2 2
MIRT563860 ZNF616 zinc finger protein 616 2 4
MIRT563879 PAGR1 PAXIP1 associated glutamate rich protein 1 2 2
MIRT564652 ZNF487P zinc finger protein 487 1 1
MIRT566595 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT570878 ZFP1 ZFP1 zinc finger protein 2 2
MIRT573067 TRIB1 tribbles pseudokinase 1 2 2
MIRT573941 ZNF708 zinc finger protein 708 2 2
MIRT575966 Slfn5 schlafen 5 2 5
MIRT607293 CD300E CD300e molecule 2 4
MIRT608187 ERBB2 erb-b2 receptor tyrosine kinase 2 2 2
MIRT609537 ADPRH ADP-ribosylarginine hydrolase 2 2
MIRT610152 PRMT8 protein arginine methyltransferase 8 2 4
MIRT611571 SLFN5 schlafen family member 5 2 7
MIRT613335 AGO2 argonaute 2, RISC catalytic component 2 4
MIRT616560 ZNF512B zinc finger protein 512B 2 2
MIRT617240 SPATS2 spermatogenesis associated serine rich 2 2 2
MIRT618011 SLC9A3R2 SLC9A3 regulator 2 2 2
MIRT618478 IL17REL interleukin 17 receptor E like 2 2
MIRT619099 IFI44L interferon induced protein 44 like 2 2
MIRT622265 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT623080 NME6 NME/NM23 nucleoside diphosphate kinase 6 2 2
MIRT625621 LILRB2 leukocyte immunoglobulin like receptor B2 2 2
MIRT627844 PLEKHA6 pleckstrin homology domain containing A6 2 2
MIRT630459 GMPS guanine monophosphate synthase 2 2
MIRT630524 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 4
MIRT631502 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT634537 MRPS17 mitochondrial ribosomal protein S17 2 2
MIRT638807 DCTN3 dynactin subunit 3 2 2
MIRT641303 SLAMF1 signaling lymphocytic activation molecule family member 1 2 2
MIRT648347 PPP1R16B protein phosphatase 1 regulatory subunit 16B 2 2
MIRT649705 ZNF175 zinc finger protein 175 2 2
MIRT652554 TLX1 T-cell leukemia homeobox 1 2 2
MIRT655564 P2RX7 purinergic receptor P2X 7 2 2
MIRT659065 DEPTOR DEP domain containing MTOR interacting protein 2 2
MIRT660341 BCAT1 branched chain amino acid transaminase 1 2 2
MIRT664330 RAB8A RAB8A, member RAS oncogene family 2 2
MIRT688934 ATXN7L3B ataxin 7 like 3B 2 2
MIRT689971 ZNF185 zinc finger protein 185 with LIM domain 2 2
MIRT699514 SKIL SKI like proto-oncogene 2 2
MIRT699975 RREB1 ras responsive element binding protein 1 2 2
MIRT702676 IRS2 insulin receptor substrate 2 2 2
MIRT709357 ULK2 unc-51 like autophagy activating kinase 2 2 2
MIRT709837 PAQR7 progestin and adipoQ receptor family member 7 2 2
MIRT718716 ANKRD18A ankyrin repeat domain 18A 2 2
MIRT718879 PDIA3 protein disulfide isomerase family A member 3 2 2
MIRT724105 TMEM199 transmembrane protein 199 2 2
MIRT724763 PSG4 pregnancy specific beta-1-glycoprotein 4 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4653 Paclitaxel 36314 NSC125973 approved sensitive High Nasopharyngeal Cancer cell line (CNE-1)
hsa-mir-4653 Paclitaxel 36314 NSC125973 approved sensitive High Nasopharyngeal Cancer cell line (CNE-1)
hsa-mir-4653 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-4653-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)

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