miRTarBase - #MIRT558488


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pre-miRNA Information
pre-miRNA hsa-mir-4282   
Genomic Coordinates chr6: 72967687 - 72967753
Description Homo sapiens miR-4282 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4282
Sequence 40| UAAAAUUUGCAUCCAGGA |57
Evidence Experimental
Experiments SOLiD
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN32074657 13 COSMIC
COSN6331413 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1195771339 5 dbSNP
rs755058572 6 dbSNP
rs1245753664 11 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol DBN1   
Synonyms D0S117E
Description drebrin 1
Transcript NM_004395   
Other Transcripts NM_080881   
Expression
Putative miRNA Targets on DBN1
3'UTR of DBN1
(miRNA target sites are highlighted)		 
>DBN1|NM_004395|3'UTR
   1 CGGTGGCGCCAGCCCTAGGCTACCCTTGCCAAGGCCGCCCACCTGCATCAGCCTCTGGCCAGACGGCCCGCCGTGCCTGC
  81 ATTCGCAGCAGCTCCGCCTGGCACCCACTCCGGATTCCGGCCCTGGCTGGGGACTTGGCCGCTTCCCTACCCACAGGGCC
 161 TGACTTTTACAGCTTTTCTCTTTTTTTAAAAAGTTGATAGGAGACTTGTACAGTTGACTGGCTTTCCTCTCGTTGGTAGT
 241 TGAGACGCTGTTGCAAATTCCACCCCTCCTTCCCTGGTCCAGATTGTAGCTCTTAGTCCTCCCTGCTCAGCTGGCCGGGT
 321 TGGAGGCCTCACCCTGCTTGGGGCCTGGCGTGGGGGGAGCTCTGGTGGGAAAATGTCCCCCACCTCTTTTCCTAGTTTTA
 401 TGTTTCTTGGGAAAATATCACTTTGTATTCTCTGTCCAGGGCTTCAGATATTTTGCACGAATTTTAAAACATGGCAATAA
 481 ATGGCTCGTGGGCTCTGGCTCCCTGGGACCCCCTCCCCGCCCTTCTTTTGACCCCTTCCTGTCTGGCCCAAAGGAAGTAG
 561 CAGGCCCAGCTGGGGCCCCTCGGCTACCCCCCGTCTCCTGCCGGGCAGGTCCCAGGTTGGAGGCCCTAGGCGCGGTTCAG
 641 GTCAGGGCTATGGATGGGGCCCAGGGGCTTTGGTGGCCCCTCCCCAACTCCTTCCTCTTTGCTTGGGTTCCTTTTTCACG
 721 TTTAGTAACTGTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGAAAGCACAAACTTCTGTAACGGGTCGTGCTCATGTCTGT
 801 TAATAAAGAAATCCAGATCC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agGACCUACGUUUAAAAu 5'
            :|| |  |:|||||| 
Target 5' ttTTGCA--CGAATTTTa 3'
 451 - 466 132.00 -5.90
2 
miRNA  3' agGACCUACGUUUAAaau 5'
            || | ||||||||   
Target 5' cgCT-GTTGCAAATTcca 3'
 246 - 262 119.00 -8.72
3 
miRNA  3' agGACCUACGUUUAAAAu 5'
            |||| | ||:||| | 
Target 5' ccCTGG-TCCAGATTGTa 3'
 272 - 288 111.00 -11.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31494342 26 COSMIC
COSN30165795 36 COSMIC
COSN30135917 37 COSMIC
COSN22622887 62 COSMIC
COSN30565882 69 COSMIC
COSN26972798 84 COSMIC
COSN26438095 98 COSMIC
COSN30101447 106 COSMIC
COSN30502009 128 COSMIC
COSN16806197 187 COSMIC
COSN31572403 246 COSMIC
COSN31563235 317 COSMIC
COSN31535620 350 COSMIC
COSN8492410 666 COSMIC
COSN31594555 681 COSMIC
COSN9422090 723 COSMIC
COSN17182900 787 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs368470978 1 dbSNP
rs769546229 1 dbSNP
rs749644699 8 dbSNP
rs773620501 10 dbSNP
rs1326267698 15 dbSNP
rs574371600 16 dbSNP
rs1417524665 20 dbSNP
rs1362097835 22 dbSNP
rs748691709 22 dbSNP
rs555696878 24 dbSNP
rs768634940 25 dbSNP
rs747191358 28 dbSNP
rs780139643 35 dbSNP
rs374930581 36 dbSNP
rs753664791 37 dbSNP
rs981679899 38 dbSNP
rs777753551 45 dbSNP
rs756080822 46 dbSNP
rs745487195 47 dbSNP
rs970004667 64 dbSNP
rs1023272972 65 dbSNP
rs1309940541 67 dbSNP
rs1374138757 68 dbSNP
rs992271359 69 dbSNP
rs960393231 70 dbSNP
rs957337198 72 dbSNP
rs1273596704 75 dbSNP
rs1339654657 80 dbSNP
rs1206779459 83 dbSNP
rs1031662801 85 dbSNP
rs998973391 94 dbSNP
rs538160706 95 dbSNP
rs901923810 96 dbSNP
rs1034374382 102 dbSNP
rs1040547324 106 dbSNP
rs1008106891 107 dbSNP
rs1389866090 109 dbSNP
rs1382656016 111 dbSNP
rs1355234686 112 dbSNP
rs1457441488 118 dbSNP
rs1378357862 119 dbSNP
rs889386628 123 dbSNP
rs1296609924 130 dbSNP
rs570852313 131 dbSNP
rs1300563169 138 dbSNP
rs774123837 140 dbSNP
rs1467187192 147 dbSNP
rs1359357981 150 dbSNP
rs1167615586 158 dbSNP
rs1297850176 159 dbSNP
rs1427455675 160 dbSNP
rs752471209 164 dbSNP
rs1489755638 167 dbSNP
rs1214857714 179 dbSNP
rs1247855824 183 dbSNP
rs552450248 187 dbSNP
rs1420528378 188 dbSNP
rs1423417781 188 dbSNP
rs1162791277 194 dbSNP
rs1036647937 198 dbSNP
rs928335769 201 dbSNP
rs534155049 204 dbSNP
rs1436968990 206 dbSNP
rs1289191116 208 dbSNP
rs892517629 208 dbSNP
rs948532361 210 dbSNP
rs1183654139 224 dbSNP
rs567037507 226 dbSNP
rs1483645216 231 dbSNP
rs1334901304 232 dbSNP
rs1051185804 233 dbSNP
rs1234490310 235 dbSNP
rs915850738 246 dbSNP
rs1327647412 254 dbSNP
rs1203228743 256 dbSNP
rs1344600723 258 dbSNP
rs111834617 273 dbSNP
rs934019819 274 dbSNP
rs1180335649 281 dbSNP
rs1258426053 286 dbSNP
rs548406609 296 dbSNP
rs899819917 302 dbSNP
rs1475564801 312 dbSNP
rs1039388076 313 dbSNP
rs530177977 317 dbSNP
rs1321037086 323 dbSNP
rs1358355072 351 dbSNP
rs556109981 352 dbSNP
rs1408718079 353 dbSNP
rs768309990 355 dbSNP
rs867424899 375 dbSNP
rs977378387 380 dbSNP
rs1327724657 381 dbSNP
rs1225913180 382 dbSNP
rs909057440 383 dbSNP
rs1355494896 388 dbSNP
rs147415882 398 dbSNP
rs1311964389 401 dbSNP
rs1306895261 402 dbSNP
rs984550046 417 dbSNP
rs1019416308 418 dbSNP
rs1007744304 424 dbSNP
rs1181581501 425 dbSNP
rs1249623371 426 dbSNP
rs1473570511 428 dbSNP
rs929139512 429 dbSNP
rs1424259258 432 dbSNP
rs889306053 433 dbSNP
rs189418085 436 dbSNP
rs1375698478 438 dbSNP
rs1428645196 439 dbSNP
rs1305650026 441 dbSNP
rs1351798013 442 dbSNP
rs72815109 444 dbSNP
rs1280627097 448 dbSNP
rs56142909 465 dbSNP
rs1372023943 471 dbSNP
rs995084990 485 dbSNP
rs898080663 487 dbSNP
rs1348874756 490 dbSNP
rs753969166 491 dbSNP
rs939656465 506 dbSNP
rs55705853 509 dbSNP
rs1205182402 510 dbSNP
rs1035754453 514 dbSNP
rs1246083283 514 dbSNP
rs562476833 514 dbSNP
rs1192715232 516 dbSNP
rs1395389294 518 dbSNP
rs1448572265 522 dbSNP
rs926284694 526 dbSNP
rs906966447 532 dbSNP
rs1166322115 536 dbSNP
rs546105261 541 dbSNP
rs1061378 543 dbSNP
rs968258405 549 dbSNP
rs1022476970 557 dbSNP
rs1009780282 563 dbSNP
rs756361955 565 dbSNP
rs1030190917 566 dbSNP
rs1349834706 567 dbSNP
rs1061379 570 dbSNP
rs528864668 576 dbSNP
rs899850827 579 dbSNP
rs1372161858 586 dbSNP
rs560267391 588 dbSNP
rs989977255 589 dbSNP
rs1295637774 590 dbSNP
rs541564661 591 dbSNP
rs574436044 592 dbSNP
rs559855512 593 dbSNP
rs765073404 593 dbSNP
rs1253461280 595 dbSNP
rs1007432335 597 dbSNP
rs1186325765 603 dbSNP
rs1374467841 605 dbSNP
rs1475510651 606 dbSNP
rs1162145417 613 dbSNP
rs887732934 615 dbSNP
rs1410988082 620 dbSNP
rs966011714 628 dbSNP
rs1328491444 631 dbSNP
rs1395726113 633 dbSNP
rs1434861432 634 dbSNP
rs1048958967 635 dbSNP
rs1318890600 638 dbSNP
rs1328437611 648 dbSNP
rs1196138680 650 dbSNP
rs1018928511 651 dbSNP
rs929170544 657 dbSNP
rs555833886 661 dbSNP
rs1246836539 672 dbSNP
rs1335403973 676 dbSNP
rs1263516001 677 dbSNP
rs192155867 677 dbSNP
rs1186383107 679 dbSNP
rs1028278503 680 dbSNP
rs1056634597 682 dbSNP
rs1475884382 685 dbSNP
rs1164957358 686 dbSNP
rs1419232959 691 dbSNP
rs569266064 694 dbSNP
rs994927537 695 dbSNP
rs1351931624 699 dbSNP
rs1387592541 699 dbSNP
rs1401566292 701 dbSNP
rs898092142 701 dbSNP
rs1015102497 705 dbSNP
rs760991269 706 dbSNP
rs1349812745 708 dbSNP
rs1262328450 710 dbSNP
rs1351098840 711 dbSNP
rs1329179478 718 dbSNP
rs1276102030 719 dbSNP
rs1385908006 720 dbSNP
rs1188056707 722 dbSNP
rs1388966699 722 dbSNP
rs1250340048 724 dbSNP
rs1295670389 725 dbSNP
rs1462364315 729 dbSNP
rs1180274100 731 dbSNP
rs1429242237 731 dbSNP
rs1172323301 732 dbSNP
rs1454606087 732 dbSNP
rs1157019508 733 dbSNP
rs1436756669 733 dbSNP
rs1003855323 735 dbSNP
rs1313566445 735 dbSNP
rs1309017980 736 dbSNP
rs1232287212 737 dbSNP
rs1272799144 737 dbSNP
rs1473642668 737 dbSNP
rs1273362410 738 dbSNP
rs1349599712 738 dbSNP
rs558854269 738 dbSNP
rs1412932198 739 dbSNP
rs1194633248 740 dbSNP
rs906889281 740 dbSNP
rs1198614325 741 dbSNP
rs1481830996 741 dbSNP
rs59430269 741 dbSNP
rs73804353 741 dbSNP
rs1299912887 742 dbSNP
rs1389672508 742 dbSNP
rs1045393287 743 dbSNP
rs1386076546 744 dbSNP
rs1264929896 745 dbSNP
rs1372887473 745 dbSNP
rs1234636731 746 dbSNP
rs1211415827 747 dbSNP
rs1296380587 747 dbSNP
rs1229009001 748 dbSNP
rs1339591032 748 dbSNP
rs894184854 749 dbSNP
rs1468852612 750 dbSNP
rs1470079964 751 dbSNP
rs1267488538 752 dbSNP
rs1206256114 753 dbSNP
rs1330560943 754 dbSNP
rs1279655790 755 dbSNP
rs1194610612 757 dbSNP
rs1232009714 759 dbSNP
rs1172624468 760 dbSNP
rs1185851682 760 dbSNP
rs1214721598 760 dbSNP
rs1244748591 760 dbSNP
rs1252183372 760 dbSNP
rs1271860466 760 dbSNP
rs1295754106 760 dbSNP
rs1319593062 760 dbSNP
rs1320579280 760 dbSNP
rs1373710066 760 dbSNP
rs1383491208 760 dbSNP
rs1396466355 760 dbSNP
rs1423288950 760 dbSNP
rs1426901955 760 dbSNP
rs1441412713 760 dbSNP
rs1457394612 760 dbSNP
rs1491053311 760 dbSNP
rs72166670 760 dbSNP
rs748471889 760 dbSNP
rs769644085 760 dbSNP
rs778355813 760 dbSNP
rs869098747 760 dbSNP
rs1329004720 761 dbSNP
rs1461846834 761 dbSNP
rs939087444 772 dbSNP
rs1343211259 775 dbSNP
rs1455077065 777 dbSNP
rs1289066430 778 dbSNP
rs926290336 781 dbSNP
rs1412408822 782 dbSNP
rs1294531843 786 dbSNP
rs1357921930 787 dbSNP
rs1234430024 788 dbSNP
rs1442174241 792 dbSNP
rs534467811 793 dbSNP
rs1218258362 796 dbSNP
rs372688836 801 dbSNP
rs1261566597 808 dbSNP
rs1054296494 812 dbSNP
rs1319181944 815 dbSNP
rs1185920337 820 dbSNP
rs980395204 821 dbSNP
rs867584165 824 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293
Disease 1627.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aggACCUACGUUUAAAAu 5'
             || |  |:|||||| 
Target 5' ---UGCA--CGAAUUUUa 3'
 		1 - 13
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714642
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000512501.1 | 3UTR | AAUUUUAAAACAUGGCAAUAAAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000512501.1 | 3UTR | UGCACGAAUUUUAAAACAUGGCAAUAAAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
280 hsa-miR-4282 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057628 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT060732 RPS3 ribosomal protein S3 2 2
MIRT063371 ETNK1 ethanolamine kinase 1 2 2
MIRT066257 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT070774 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT070871 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT078056 PCTP phosphatidylcholine transfer protein 2 2
MIRT078408 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT084059 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT093537 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096072 SFXN1 sideroflexin 1 2 2
MIRT098316 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT100493 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT102254 HBP1 HMG-box transcription factor 1 2 4
MIRT105318 VPS37A VPS37A, ESCRT-I subunit 2 2
MIRT114143 MZT1 mitotic spindle organizing protein 1 2 4
MIRT114873 DICER1 dicer 1, ribonuclease III 2 2
MIRT134683 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT137640 RCOR1 REST corepressor 1 2 2
MIRT155449 CCNT2 cyclin T2 2 4
MIRT165656 DCTN4 dynactin subunit 4 2 2
MIRT177570 CSTF2T cleavage stimulation factor subunit 2 tau variant 2 4
MIRT188514 E2F7 E2F transcription factor 7 2 10
MIRT193019 TMOD3 tropomodulin 3 2 4
MIRT195823 GADD45A growth arrest and DNA damage inducible alpha 2 2
MIRT195885 DEPDC1 DEP domain containing 1 2 6
MIRT206029 NUP50 nucleoporin 50 2 6
MIRT212148 CLCN3 chloride voltage-gated channel 3 2 2
MIRT213999 DCP2 decapping mRNA 2 2 2
MIRT214650 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 2
MIRT221568 CBX3 chromobox 3 2 2
MIRT224544 ZNF623 zinc finger protein 623 2 2
MIRT227654 SET SET nuclear proto-oncogene 2 2
MIRT229992 CHIC1 cysteine rich hydrophobic domain 1 2 2
MIRT238968 QKI QKI, KH domain containing RNA binding 2 2
MIRT239825 ACTB actin beta 2 2
MIRT241084 ZXDA zinc finger, X-linked, duplicated A 2 4
MIRT244852 ZBTB5 zinc finger and BTB domain containing 5 2 2
MIRT264534 TARDBP TAR DNA binding protein 2 2
MIRT271438 SKI SKI proto-oncogene 2 2
MIRT271597 ENAH ENAH, actin regulator 2 2
MIRT294332 ZNF264 zinc finger protein 264 2 2
MIRT296341 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT301715 TEF TEF, PAR bZIP transcription factor 2 2
MIRT308549 ZNF654 zinc finger protein 654 2 2
MIRT313866 DEPDC1B DEP domain containing 1B 2 2
MIRT315529 MARCKS myristoylated alanine rich protein kinase C substrate 2 2
MIRT321066 RABGEF1 RAB guanine nucleotide exchange factor 1 2 2
MIRT343777 NUTF2 nuclear transport factor 2 2 2
MIRT359109 MAP1B microtubule associated protein 1B 2 2
MIRT397393 GOLGA3 golgin A3 2 4
MIRT400822 CPEB2 cytoplasmic polyadenylation element binding protein 2 2 2
MIRT442171 DSEL dermatan sulfate epimerase-like 2 2
MIRT442777 JAG1 jagged 1 2 2
MIRT442862 SCARF1 scavenger receptor class F member 1 2 4
MIRT442919 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT444567 TRA2B transformer 2 beta homolog 2 2
MIRT444718 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT445018 RBMS3 RNA binding motif single stranded interacting protein 3 2 2
MIRT445853 LRRC1 leucine rich repeat containing 1 2 2
MIRT446242 HELZ helicase with zinc finger 2 2
MIRT446542 GOLGA8B golgin A8 family member B 2 2
MIRT446643 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT446948 ZMAT3 zinc finger matrin-type 3 2 4
MIRT447061 KCNAB1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 2 2
MIRT447327 ZSCAN21 zinc finger and SCAN domain containing 21 2 2
MIRT447995 CDX1 caudal type homeobox 1 2 2
MIRT448543 RHEBP1 RHEB pseudogene 1 2 6
MIRT448752 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT448772 GOLGA8A golgin A8 family member A 2 2
MIRT449342 WDR26 WD repeat domain 26 2 2
MIRT450011 SLC16A6 solute carrier family 16 member 6 2 4
MIRT450229 PCNX pecanex homolog 1 2 2
MIRT450340 MRPL17 mitochondrial ribosomal protein L17 2 4
MIRT450381 MSI2 musashi RNA binding protein 2 2 2
MIRT450759 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT450809 NRCAM neuronal cell adhesion molecule 2 2
MIRT450947 ATAD2 ATPase family, AAA domain containing 2 2 2
MIRT459095 CCPG1 cell cycle progression 1 2 2
MIRT462428 TWISTNB TWIST neighbor 2 2
MIRT465200 TROVE2 TROVE domain family member 2 2 4
MIRT467382 SON SON DNA binding protein 2 4
MIRT468546 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT471506 PDE4D phosphodiesterase 4D 2 2
MIRT471981 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT474478 KLHL11 kelch like family member 11 2 8
MIRT475011 KANSL1 KAT8 regulatory NSL complex subunit 1 2 8
MIRT480341 C5orf51 chromosome 5 open reading frame 51 2 2
MIRT482696 TEX9 testis expressed 9 2 6
MIRT483462 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 6
MIRT485623 FAM217B family with sequence similarity 217 member B 2 2
MIRT485714 CASP16 caspase 16, pseudogene 2 8
MIRT486279 SEC23A Sec23 homolog A, coat complex II component 2 2
MIRT491000 PEBP1 phosphatidylethanolamine binding protein 1 2 4
MIRT492594 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT493365 KIF5B kinesin family member 5B 2 2
MIRT494316 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT495208 EDN3 endothelin 3 2 2
MIRT497011 TCF15 transcription factor 15 2 2
MIRT498512 FRK fyn related Src family tyrosine kinase 2 2
MIRT498778 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT501045 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502939 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504806 VHL von Hippel-Lindau tumor suppressor 2 6
MIRT505656 SHMT1 serine hydroxymethyltransferase 1 2 6
MIRT505964 RAB5C RAB5C, member RAS oncogene family 2 6
MIRT506322 OTUD4 OTU deubiquitinase 4 2 4
MIRT506803 KLHL15 kelch like family member 15 2 6
MIRT506917 KBTBD8 kelch repeat and BTB domain containing 8 2 4
MIRT507400 EMC7 ER membrane protein complex subunit 7 2 8
MIRT507471 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 6
MIRT508058 ATP13A3 ATPase 13A3 2 4
MIRT508135 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT509895 RPS23 ribosomal protein S23 2 4
MIRT510881 RAN RAN, member RAS oncogene family 2 8
MIRT513766 PEX5L peroxisomal biogenesis factor 5 like 2 4
MIRT516898 COPS8 COP9 signalosome subunit 8 2 2
MIRT518703 TIMD4 T-cell immunoglobulin and mucin domain containing 4 2 4
MIRT520429 TTPAL alpha tocopherol transfer protein like 2 6
MIRT521843 PNISR PNN interacting serine and arginine rich protein 2 4
MIRT522116 NUDT3 nudix hydrolase 3 2 4
MIRT525467 TMPRSS12 transmembrane protease, serine 12 2 2
MIRT525583 MTRNR2L7 MT-RNR2-like 7 2 2
MIRT525906 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT526072 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT526232 MTRNR2L5 MT-RNR2-like 5 2 4
MIRT526455 FAM71F2 family with sequence similarity 71 member F2 2 4
MIRT526515 POU5F1B POU class 5 homeobox 1B 2 2
MIRT528032 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT528422 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT528995 ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 2 4
MIRT529311 ATRNL1 attractin like 1 2 2
MIRT529376 SKP1 S-phase kinase associated protein 1 2 4
MIRT530015 SRRM1 serine and arginine repetitive matrix 1 2 2
MIRT530089 FMN2 formin 2 2 2
MIRT530942 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2 2
MIRT531229 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT533088 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT533299 USP46 ubiquitin specific peptidase 46 2 2
MIRT533318 UNKL unkempt family like zinc finger 2 2
MIRT533721 TMEM30A transmembrane protein 30A 2 2
MIRT534096 AZF1 azoospermia factor 1 2 2
MIRT534188 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534493 SAR1B secretion associated Ras related GTPase 1B 2 2
MIRT536077 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT536242 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT537524 FAM104A family with sequence similarity 104 member A 2 2
MIRT538088 DGKH diacylglycerol kinase eta 2 2
MIRT538475 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT538853 BTG1 BTG anti-proliferation factor 1 2 4
MIRT539075 GDNF glial cell derived neurotrophic factor 2 2
MIRT539480 ACVR2B activin A receptor type 2B 2 4
MIRT540210 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT541940 TSPAN2 tetraspanin 2 2 2
MIRT543812 COCH cochlin 2 2
MIRT545120 PDZRN4 PDZ domain containing ring finger 4 2 2
MIRT545571 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT545989 XKR4 XK related 4 2 2
MIRT547213 PANK3 pantothenate kinase 3 2 4
MIRT547740 KIAA1468 KIAA1468 2 2
MIRT548022 GRB2 growth factor receptor bound protein 2 2 4
MIRT548032 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548102 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 4
MIRT548217 FKBP1A FK506 binding protein 1A 2 2
MIRT548588 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT548953 CDC27 cell division cycle 27 2 2
MIRT549072 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT550368 INCENP inner centromere protein 2 6
MIRT550546 MYZAP myocardial zonula adherens protein 2 2
MIRT551491 TMEM192 transmembrane protein 192 2 4
MIRT553078 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT554104 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT555127 PTPRG protein tyrosine phosphatase, receptor type G 2 2
MIRT555477 POC1B-GALNT4 POC1B-GALNT4 readthrough 2 2
MIRT555978 NPTN neuroplastin 2 2
MIRT557011 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557706 GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 2 2
MIRT558333 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT558488 DBN1 drebrin 1 2 2
MIRT559942 ZNF567 zinc finger protein 567 2 2
MIRT561127 ATP2B1 ATPase plasma membrane Ca2+ transporting 1 2 2
MIRT561791 PAWR pro-apoptotic WT1 regulator 2 2
MIRT562438 EEF2 eukaryotic translation elongation factor 2 2 2
MIRT563102 PABPC4L poly(A) binding protein cytoplasmic 4 like 2 2
MIRT563212 ZNF813 zinc finger protein 813 2 2
MIRT563426 KIF3A kinesin family member 3A 2 2
MIRT563473 SPIN4 spindlin family member 4 2 2
MIRT564015 HSPA4 heat shock protein family A (Hsp70) member 4 2 4
MIRT564117 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT564223 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT564503 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 2 2
MIRT564515 DUSP3 dual specificity phosphatase 3 2 2
MIRT564811 ZBTB21 zinc finger and BTB domain containing 21 2 2
MIRT565265 TPD52 tumor protein D52 2 2
MIRT566012 RHOB ras homolog family member B 2 2
MIRT566216 PTMA prothymosin, alpha 2 2
MIRT566638 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT566821 MAPK8 mitogen-activated protein kinase 8 2 2
MIRT566948 LEPROT leptin receptor overlapping transcript 2 2
MIRT567290 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT567895 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT568731 MTRNR2L3 MT-RNR2-like 3 2 2
MIRT571263 ZNF239 zinc finger protein 239 2 2
MIRT572593 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2 2
MIRT573827 TGOLN2 trans-golgi network protein 2 2 2
MIRT576391 Fhl2 four and a half LIM domains 2 2 2
MIRT609901 SMS spermine synthase 2 2
MIRT613710 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT614406 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT615042 DCX doublecortin 2 2
MIRT617514 C5orf45 MRN complex interacting protein 2 2
MIRT619476 PRDM10 PR/SET domain 10 2 2
MIRT620349 TLN1 talin 1 2 2
MIRT620910 PLA2G7 phospholipase A2 group VII 2 2
MIRT622131 SP4 Sp4 transcription factor 2 2
MIRT622955 OTUD7B OTU deubiquitinase 7B 2 2
MIRT623351 MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 2 2
MIRT623619 INTU inturned planar cell polarity protein 2 2
MIRT624409 CCDC171 coiled-coil domain containing 171 2 2
MIRT625171 CCS copper chaperone for superoxide dismutase 2 2
MIRT625685 RPP40 ribonuclease P/MRP subunit p40 2 2
MIRT625875 ALDH18A1 aldehyde dehydrogenase 18 family member A1 2 2
MIRT626002 FAM107A family with sequence similarity 107 member A 2 2
MIRT626872 HRH4 histamine receptor H4 2 4
MIRT628220 FKBP9 FK506 binding protein 9 2 2
MIRT628265 DIO2 iodothyronine deiodinase 2 2 2
MIRT628402 C8orf37 chromosome 8 open reading frame 37 2 2
MIRT630564 C3orf36 chromosome 3 open reading frame 36 2 4
MIRT631577 RASSF9 Ras association domain family member 9 2 2
MIRT635730 CCDC58 coiled-coil domain containing 58 2 2
MIRT636224 SLC8A1 solute carrier family 8 member A1 2 2
MIRT636613 CLIC5 chloride intracellular channel 5 2 2
MIRT638899 CDK9 cyclin dependent kinase 9 2 2
MIRT640167 ATXN7L1 ataxin 7 like 1 2 2
MIRT642070 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT643034 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 2 2
MIRT644572 SPOP speckle type BTB/POZ protein 2 2
MIRT644954 IFNB1 interferon beta 1 2 2
MIRT645948 TTF2 transcription termination factor 2 2 2
MIRT646440 XRCC2 X-ray repair cross complementing 2 2 2
MIRT647896 EPN2 epsin 2 2 2
MIRT648276 ZNF582 zinc finger protein 582 2 2
MIRT649381 NEDD1 neural precursor cell expressed, developmentally down-regulated 1 2 2
MIRT650254 CD68 CD68 molecule 2 2
MIRT650333 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT651707 VMP1 vacuole membrane protein 1 2 2
MIRT651774 VASP vasodilator stimulated phosphoprotein 2 2
MIRT653144 SRPK2 SRSF protein kinase 2 2 2
MIRT654112 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT654161 RORB RAR related orphan receptor B 2 2
MIRT655716 MLF2 myeloid leukemia factor 2 2 2
MIRT657476 HDAC4 histone deacetylase 4 2 2
MIRT658095 FOXO1 forkhead box O1 2 2
MIRT658860 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT658988 DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 2 2
MIRT660767 ALDH6A1 aldehyde dehydrogenase 6 family member A1 2 2
MIRT661622 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT661694 TFDP2 transcription factor Dp-2 2 2
MIRT662208 PLA2G4E phospholipase A2 group IVE 2 2
MIRT662443 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT664422 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT687505 NECAB1 N-terminal EF-hand calcium binding protein 1 2 2
MIRT689910 SOD2 superoxide dismutase 2 2 2
MIRT690781 PLA2G2C phospholipase A2 group IIC 2 2
MIRT698488 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT699685 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT700926 PDS5A PDS5 cohesin associated factor A 2 2
MIRT702258 LMNB1 lamin B1 2 2
MIRT703166 GPR137C G protein-coupled receptor 137C 2 2
MIRT703242 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT704737 CENPQ centromere protein Q 2 2
MIRT707310 GLRX2 glutaredoxin 2 2 2
MIRT710021 KCNQ5 potassium voltage-gated channel subfamily Q member 5 2 2
MIRT712212 SCOC short coiled-coil protein 2 2
MIRT714742 SETBP1 SET binding protein 1 2 2
MIRT718268 ZNF749 zinc finger protein 749 2 2
MIRT720553 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT722248 RBM41 RNA binding motif protein 41 2 2
MIRT723767 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT723977 KIAA0146 scaffolding protein involved in DNA repair 1 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4282 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)

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