pre-miRNA Information
pre-miRNA hsa-mir-1245a   
Genomic Coordinates chr2: 188978092 - 188978161
Description Homo sapiens miR-1245a stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-1245a
Sequence 45| AAGUGAUCUAAAGGCCUACAU |65
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN31562560 15 COSMIC
COSN26581044 19 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs906938680 2 dbSNP
rs1159117523 3 dbSNP
rs780486044 6 dbSNP
rs771479866 17 dbSNP
rs1002976932 18 dbSNP
rs1428029219 19 dbSNP
Putative Targets

Gene Information
Gene Symbol DDIT4   
Synonyms Dig2, REDD-1, REDD1
Description DNA damage inducible transcript 4
Transcript NM_019058   
Expression
Putative miRNA Targets on DDIT4
3'UTR of DDIT4
(miRNA target sites are highlighted)
>DDIT4|NM_019058|3'UTR
   1 ACTTCAACCTGAGGGGGCCGACAGTGCCCTCCAAGACAGAGACGACTGAACTTTTGGGGTGGAGACTAGAGGCAGGAGCT
  81 GAGGGACTGATTCCTGTGGTTGGAAAACTGAGGCAGCCACCTAAGGTGGAGGTGGGGGAATAGTGTTTCCCAGGAAGCTC
 161 ATTGAGTTGTGTGCGGGTGGCTGTGCATTGGGGACACATACCCCTCAGTACTGTAGCATGAAACAAAGGCTTAGGGGCCA
 241 ACAAGGCTTCCAGCTGGATGTGTGTGTAGCATGTACCTTATTATTTTTGTTACTGACAGTTAACAGTGGTGTGACATCCA
 321 GAGAGCAGCTGGGCTGCTCCCGCCCCAGCCCGGCCCAGGGTGAAGGAAGAGGCACGTGCTCCTCAGAGCAGCCGGAGGGA
 401 GGGGGGAGGTCGGAGGTCGTGGAGGTGGTTTGTGTATCTTACTGGTCTGAAGGGACCAAGTGTGTTTGTTGTTTGTTTTG
 481 TATCTTGTTTTTCTGATCGGAGCATCACTACTGACCTGTTGTAGGCAGCTATCTTACAGACGCATGAATGTAAGAGTAGG
 561 AAGGGGTGGGTGTCAGGGATCACTTGGGATCTTTGACACTTGAAAAATTACACCTGGCAGCTGCGTTTAAGCCTTCCCCC
 641 ATCGTGTACTGCAGAGTTGAGCTGGCAGGGGAGGGGCTGAGAGGGTGGGGGCTGGAACCCCTCCCCGGGAGGAGTGCCAT
 721 CTGGGTCTTCCATCTAGAACTGTTTACATGAAGATAAGATACTCACTGTTCATGAATACACTTGATGTTCAAGTATTAAG
 801 ACCTATGCAATATTTTTTACTTTTCTAATAAACATGTTTGTTAAAACAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' uaCAUCCGGA-AAUCUAGUGAa 5'
            ||:||: |   :||||||| 
Target 5' ggGTGGGTGTCAGGGATCACTt 3'
564 - 585 151.00 -18.20
2
miRNA  3' uacauccggaaaucUAGUGAa 5'
                        |||||| 
Target 5' tttctgatcggagcATCACTa 3'
490 - 510 120.00 -6.50
3
miRNA  3' uaCAUCCGGAAAUCUAGUGAa 5'
            |||  ||||   ||:|:| 
Target 5' atGTA--CCTT---ATTATTt 3'
271 - 286 95.00 -6.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM8897215 1 COSMIC
COSN30150322 12 COSMIC
COSN30157065 45 COSMIC
COSN30470738 48 COSMIC
COSN30506295 76 COSMIC
COSN31502000 100 COSMIC
COSN26548479 146 COSMIC
COSN26635572 258 COSMIC
COSN31533003 325 COSMIC
COSN31538528 615 COSMIC
COSN15662301 696 COSMIC
COSN21532953 698 COSMIC
COSN31543760 738 COSMIC
COSN29343971 746 COSMIC
COSN31607106 779 COSMIC
COSN31607795 791 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs763173766 6 dbSNP
rs1358766386 8 dbSNP
rs766220053 9 dbSNP
rs745432530 10 dbSNP
rs753737141 11 dbSNP
rs1175636860 12 dbSNP
rs1435347549 13 dbSNP
rs759476392 13 dbSNP
rs764672067 13 dbSNP
rs1389797238 15 dbSNP
rs766528270 19 dbSNP
rs188610989 20 dbSNP
rs371515105 21 dbSNP
rs1181836310 22 dbSNP
rs781646796 23 dbSNP
rs1283012194 24 dbSNP
rs965033154 29 dbSNP
rs1281037674 31 dbSNP
rs145882456 34 dbSNP
rs1216319415 36 dbSNP
rs1262204352 37 dbSNP
rs752265549 38 dbSNP
rs936381031 38 dbSNP
rs1280554559 43 dbSNP
rs755617872 44 dbSNP
rs1215745495 52 dbSNP
rs1296056566 57 dbSNP
rs555796943 60 dbSNP
rs1359502892 69 dbSNP
rs923325246 74 dbSNP
rs775533376 75 dbSNP
rs1364286695 80 dbSNP
rs1166409569 83 dbSNP
rs1463698106 92 dbSNP
rs1053639 96 dbSNP
rs914735868 97 dbSNP
rs947573858 101 dbSNP
rs1044628139 105 dbSNP
rs573438704 109 dbSNP
rs541358689 123 dbSNP
rs1474399490 126 dbSNP
rs1260303642 130 dbSNP
rs1341638660 134 dbSNP
rs1217653980 139 dbSNP
rs1046523619 140 dbSNP
rs1278242561 143 dbSNP
rs1193522890 152 dbSNP
rs553561927 163 dbSNP
rs1251460847 165 dbSNP
rs906430620 166 dbSNP
rs1443249149 173 dbSNP
rs1002557726 175 dbSNP
rs1415286794 176 dbSNP
rs1350000974 177 dbSNP
rs1326954865 178 dbSNP
rs113957659 180 dbSNP
rs1397506061 188 dbSNP
rs763959603 189 dbSNP
rs56922371 190 dbSNP
rs1005556271 193 dbSNP
rs777228453 194 dbSNP
rs545115692 198 dbSNP
rs1166355218 199 dbSNP
rs1472565245 201 dbSNP
rs773238622 203 dbSNP
rs1056152880 213 dbSNP
rs896164110 214 dbSNP
rs563413675 215 dbSNP
rs72808106 216 dbSNP
rs1274787594 225 dbSNP
rs139902355 240 dbSNP
rs760943369 243 dbSNP
rs371084507 251 dbSNP
rs936162036 266 dbSNP
rs1006014469 272 dbSNP
rs1336425799 277 dbSNP
rs1415824292 290 dbSNP
rs1438956881 292 dbSNP
rs1017445161 294 dbSNP
rs1327030735 295 dbSNP
rs912501798 299 dbSNP
rs10566169 305 dbSNP
rs561122223 309 dbSNP
rs964675273 314 dbSNP
rs1160785586 325 dbSNP
rs913649117 325 dbSNP
rs976425928 326 dbSNP
rs1470915431 328 dbSNP
rs1030317139 330 dbSNP
rs757088196 339 dbSNP
rs956268407 339 dbSNP
rs988891592 342 dbSNP
rs529214151 343 dbSNP
rs947502367 344 dbSNP
rs879562833 345 dbSNP
rs906203576 349 dbSNP
rs547357570 351 dbSNP
rs8316 352 dbSNP
rs192124186 353 dbSNP
rs1057511920 354 dbSNP
rs1373475454 355 dbSNP
rs551501864 357 dbSNP
rs1434902166 361 dbSNP
rs1325044785 367 dbSNP
rs1258721860 375 dbSNP
rs888248523 376 dbSNP
rs184518925 379 dbSNP
rs531689161 384 dbSNP
rs1402057602 388 dbSNP
rs1209884692 394 dbSNP
rs1250393777 395 dbSNP
rs529135088 395 dbSNP
rs1450424348 397 dbSNP
rs1005333913 401 dbSNP
rs13618 402 dbSNP
rs555389637 403 dbSNP
rs567132197 404 dbSNP
rs1410910373 405 dbSNP
rs1005984942 407 dbSNP
rs1214170980 413 dbSNP
rs549946092 416 dbSNP
rs1017371531 417 dbSNP
rs900360018 420 dbSNP
rs1161126208 421 dbSNP
rs535363121 426 dbSNP
rs553357444 430 dbSNP
rs1030703002 435 dbSNP
rs758053528 437 dbSNP
rs954187265 439 dbSNP
rs1386157677 440 dbSNP
rs1311528995 442 dbSNP
rs1412461604 443 dbSNP
rs1322960796 447 dbSNP
rs1331822239 448 dbSNP
rs1406963029 452 dbSNP
rs144800618 457 dbSNP
rs1350126481 463 dbSNP
rs1173935394 466 dbSNP
rs1229350579 466 dbSNP
rs1010248187 467 dbSNP
rs1262869960 472 dbSNP
rs1021688171 481 dbSNP
rs1169435831 483 dbSNP
rs1475585946 485 dbSNP
rs1256792808 497 dbSNP
rs1185705122 498 dbSNP
rs1486717343 499 dbSNP
rs1258287448 500 dbSNP
rs957646399 503 dbSNP
rs1203845971 505 dbSNP
rs1306010673 506 dbSNP
rs1275294561 508 dbSNP
rs1215532709 520 dbSNP
rs968809699 527 dbSNP
rs1334609863 538 dbSNP
rs1235659282 539 dbSNP
rs1356610416 542 dbSNP
rs988958589 542 dbSNP
rs368555846 543 dbSNP
rs1330460531 545 dbSNP
rs980205958 547 dbSNP
rs945115347 557 dbSNP
rs879520062 559 dbSNP
rs1476158503 560 dbSNP
rs1418431474 561 dbSNP
rs1176692216 564 dbSNP
rs189403403 567 dbSNP
rs1234868996 570 dbSNP
rs960521872 573 dbSNP
rs927614438 574 dbSNP
rs993093939 580 dbSNP
rs1490708158 584 dbSNP
rs1271690329 586 dbSNP
rs1179537610 590 dbSNP
rs754439207 610 dbSNP
rs1250545689 614 dbSNP
rs1336116376 618 dbSNP
rs937684781 625 dbSNP
rs1472730021 627 dbSNP
rs1054755197 633 dbSNP
rs1184015294 636 dbSNP
rs1370536245 636 dbSNP
rs888361470 638 dbSNP
rs918838647 640 dbSNP
rs928941434 642 dbSNP
rs557123637 644 dbSNP
rs575380386 645 dbSNP
rs897007499 652 dbSNP
rs998240179 654 dbSNP
rs941769202 662 dbSNP
rs1366563912 666 dbSNP
rs1030167905 672 dbSNP
rs1457344454 677 dbSNP
rs1163815539 682 dbSNP
rs1391520542 698 dbSNP
rs1251302328 699 dbSNP
rs756881224 700 dbSNP
rs559083746 702 dbSNP
rs1063932 703 dbSNP
rs36108637 703 dbSNP
rs542732458 707 dbSNP
rs561367340 708 dbSNP
rs1426575937 710 dbSNP
rs1214233068 733 dbSNP
rs532982371 738 dbSNP
rs900331214 741 dbSNP
rs997761602 754 dbSNP
rs1285774708 761 dbSNP
rs1370115759 765 dbSNP
rs11192 771 dbSNP
rs1300728776 773 dbSNP
rs1309586909 775 dbSNP
rs1339146323 781 dbSNP
rs1288269086 796 dbSNP
rs541338882 797 dbSNP
rs1033031517 801 dbSNP
rs957594126 803 dbSNP
rs775803379 812 dbSNP
rs989073416 819 dbSNP
rs1020439257 822 dbSNP
rs1455011994 835 dbSNP
rs971976681 835 dbSNP
rs1010218657 837 dbSNP
rs1021617589 839 dbSNP
rs1202352463 848 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' uacauccggaaaucUAGUGAa 5'
                        |||||| 
Target 5' uuucugaucggagcAUCACUa 3'
3 - 23
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545212
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / Control
Location of target site ENST00000307365.3 | 3UTR | UUUUUCUGAUCGGAGCAUCACUACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000307365.3 | 3UTR | UUUUUCUGAUCGGAGCAUCACUAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
UCEC 0.985 0.06 1.000 0.5 3 Click to see details
HNSC -0.421 0.17 -0.464 0.15 7 Click to see details
BLCA 0.367 0.38 0.500 0.33 3 Click to see details
BRCA -0.325 0.39 0.500 0.33 3 Click to see details
BRCA -0.325 0.39 0.500 0.33 3 Click to see details
BRCA -0.325 0.39 0.500 0.33 3 Click to see details
BRCA -0.325 0.39 0.500 0.33 3 Click to see details
BRCA -0.325 0.39 0.500 0.33 3 Click to see details
109 hsa-miR-1245a Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT006574 BRCA2 BRCA2, DNA repair associated 2 1
MIRT055432 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 2
MIRT063879 RASSF8 Ras association domain family member 8 2 6
MIRT077025 WIPF2 WAS/WASL interacting protein family member 2 2 2
MIRT095775 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT099172 MAP3K4 mitogen-activated protein kinase kinase kinase 4 2 2
MIRT175616 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT456518 LYPLAL1 lysophospholipase like 1 2 2
MIRT464457 UGCG UDP-glucose ceramide glucosyltransferase 2 2
MIRT465747 TMPPE transmembrane protein with metallophosphoesterase domain 2 2
MIRT468257 SFXN4 sideroflexin 4 2 2
MIRT469216 RICTOR RPTOR independent companion of MTOR complex 2 2 2
MIRT472045 NPAT nuclear protein, coactivator of histone transcription 2 2
MIRT481795 APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 2 2
MIRT500154 CREBBP CREB binding protein 2 2
MIRT506514 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 4
MIRT506915 KBTBD8 kelch repeat and BTB domain containing 8 2 6
MIRT513901 GRB10 growth factor receptor bound protein 10 2 6
MIRT519128 ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2 2
MIRT528121 FOXH1 forkhead box H1 2 2
MIRT528942 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT540580 CEP89 centrosomal protein 89 2 2
MIRT545858 ZNF264 zinc finger protein 264 2 4
MIRT547147 PGM3 phosphoglucomutase 3 2 2
MIRT547434 MED4 mediator complex subunit 4 2 2
MIRT554650 ROBO1 roundabout guidance receptor 1 2 2
MIRT558524 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT559762 ABHD5 abhydrolase domain containing 5 2 2
MIRT560438 GOLGA7B golgin A7 family member B 2 2
MIRT561974 LRRC59 leucine rich repeat containing 59 2 2
MIRT562442 DDIT4 DNA damage inducible transcript 4 2 2
MIRT563489 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT568265 BMP2K BMP2 inducible kinase 2 2
MIRT572522 KIAA0232 KIAA0232 2 2
MIRT612801 LSM14A LSM14A, mRNA processing body assembly factor 2 2
MIRT621533 ZNF507 zinc finger protein 507 2 2
MIRT625205 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT625615 ZNF84 zinc finger protein 84 2 2
MIRT629215 C12orf66 chromosome 12 open reading frame 66 2 2
MIRT629509 AS3MT arsenite methyltransferase 2 2
MIRT629769 STK25 serine/threonine kinase 25 2 2
MIRT630908 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT632508 RAB13 RAB13, member RAS oncogene family 2 2
MIRT636871 ARSE arylsulfatase E (chondrodysplasia punctata 1) 2 2
MIRT637106 CXorf23 BCLAF1 and THRAP3 family member 3 2 2
MIRT637332 FAM9B family with sequence similarity 9 member B 2 2
MIRT637553 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT637639 ZNF431 zinc finger protein 431 2 2
MIRT637836 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT638326 RNF11 ring finger protein 11 2 2
MIRT638393 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT642450 CLUAP1 clusterin associated protein 1 2 2
MIRT642616 APOPT1 apoptogenic 1, mitochondrial 2 2
MIRT643133 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT644324 NFKBID NFKB inhibitor delta 2 2
MIRT645150 DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 2 2
MIRT645673 ADK adenosine kinase 2 2
MIRT646091 MGST3 microsomal glutathione S-transferase 3 2 2
MIRT646858 SLC35E4 solute carrier family 35 member E4 2 2
MIRT650153 ZNF426 zinc finger protein 426 2 2
MIRT652483 TMEM181 transmembrane protein 181 2 2
MIRT653790 SIRPA signal regulatory protein alpha 2 2
MIRT655526 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 2
MIRT657077 JPH2 junctophilin 2 2 2
MIRT657322 HOOK3 hook microtubule tethering protein 3 2 2
MIRT662036 FUT2 fucosyltransferase 2 2 2
MIRT662322 ADM2 adrenomedullin 2 2 2
MIRT663211 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT663559 CCR6 C-C motif chemokine receptor 6 2 2
MIRT663937 ZNF554 zinc finger protein 554 2 2
MIRT664689 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT664709 PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 2
MIRT665291 ZFP14 ZFP14 zinc finger protein 2 2
MIRT665572 TXNL1 thioredoxin like 1 2 2
MIRT667068 PAOX polyamine oxidase 2 2
MIRT667304 MYO5A myosin VA 2 2
MIRT667442 METTL14 methyltransferase like 14 2 2
MIRT668048 GTPBP10 GTP binding protein 10 2 2
MIRT669604 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT671088 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT674361 SLC35E3 solute carrier family 35 member E3 2 2
MIRT674962 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT676394 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT676819 AGMAT agmatinase 2 2
MIRT676891 ENSA endosulfine alpha 2 2
MIRT677059 ZNF34 zinc finger protein 34 2 2
MIRT678424 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678735 SRCAP Snf2 related CREBBP activator protein 2 2
MIRT678930 XPOT exportin for tRNA 2 2
MIRT678954 MYADM myeloid associated differentiation marker 2 2
MIRT679228 MAN2A2 mannosidase alpha class 2A member 2 2 2
MIRT679765 TLR6 toll like receptor 6 2 2
MIRT681992 HRH4 histamine receptor H4 2 2
MIRT687405 NSUN4 NOP2/Sun RNA methyltransferase family member 4 2 2
MIRT694570 RBMXL1 RNA binding motif protein, X-linked like 1 2 2
MIRT698449 TM4SF1 transmembrane 4 L six family member 1 2 2
MIRT706406 HAS2 hyaluronan synthase 2 2 2
MIRT706582 ZNF432 zinc finger protein 432 2 2
MIRT706838 VHLL VHL like 2 2
MIRT706909 DVL3 dishevelled segment polarity protein 3 2 2
MIRT707052 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT708583 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT708988 CABP4 calcium binding protein 4 2 2
MIRT713041 ADRA2B adrenoceptor alpha 2B 2 2
MIRT713731 SUCO SUN domain containing ossification factor 2 2
MIRT714968 RAB21 RAB21, member RAS oncogene family 2 2
MIRT717485 PDE4DIP phosphodiesterase 4D interacting protein 2 2
MIRT722826 KLK2 kallikrein related peptidase 2 2 2
MIRT723305 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-1245a Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (M14) (500nM)
hsa-miR-1245a Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (M14) (500nM)
hsa-miR-1245a Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (M14) (1uM)
hsa-miR-1245a Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (M14) (1uM)
hsa-miR-1245a Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-1245a Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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