miRTarBase - #MIRT563624


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pre-miRNA Information
pre-miRNA hsa-mir-367   
Genomic Coordinates chr4: 112647874 - 112647941
Synonyms MIRN367, hsa-mir-367, MIR367
Description Homo sapiens miR-367 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-367-3p
Sequence 44| AAUUGCACUUUAGCAAUGGUGA |65
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN24411246 17 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs535597757 1 dbSNP
rs1013348949 11 dbSNP
rs896333735 12 dbSNP
rs751269136 14 dbSNP
rs1163501507 16 dbSNP
rs757092597 21 dbSNP
Putative Targets

Gene Information
Gene Symbol ZNF277   
Synonyms NRIF4, ZNF277P
Description zinc finger protein 277
Transcript NM_021994   
Expression
Putative miRNA Targets on ZNF277
3'UTR of ZNF277
(miRNA target sites are highlighted)		 
>ZNF277|NM_021994|3'UTR
   1 GAGTACTTGAAAACCTAGAAGAAACTACCACAGAAGCAATTTTTCATGTTTTTCTCCTATGAGACAGATATGAAAGAACA
  81 ATTTAAATTTGAACATCAACAAAAGATTGGTCCTTGGTGAAATAAACTTTTCAAAAATGAATGTTCTTTTCAAAAAATAA
 161 AGTAGAAAAATGCACTTACTAAGAACATGAAAAAAAATGAAGTAGGAAAATAAGATGAAGACTTTGTATTTTGGCTGTAA
 241 AGTTTTATTGTGTGATCATCTTAAATTATCTCACTTCATTAAACTCATAATTATATATAGAAGTATATGTCAATTACAAA
 321 GAAATGAAATGTTCAAATTATTTATAAACCTGATTTTTCAATCAGTAGTTTCAGTCTCCTCCCCAAGGACCTTCTTCATC
 401 CAACAAGTTGCAAAATTTGAATATCCCTTCTGTACTATATTGGGTGAGCTGTAAATGTAATGACTAAAAGAAAAGCCACA
 481 GAAGAAAGAAGAAATGGTCAAAGACGTGGATAATATGCAAATTGGCCATTATATTAGAACAATCAAGAGCTGACTGTGTT
 561 ATTACCACTTTCTGCCTAGGGTGGCCAAATTCCCTAGAAATAGACATCAAGCCAGTTAACTTCACTTTTCCCTGCAATTT
 641 GTATGTCACTAACATTTAAATGCCATTTTTTAAAAACATAACCACAATACCATTATGACACCTAAAAAACATTAACATTA
 721 ACTTAATATCATCTGTTTTCAGTTTTTCCCACTTGTCTCAAAATGTATGTTTACAATATTATCAGTTTCATTACTGATGA
 801 ATATTATATGCCTCCTGATAAGATGTACTGAGGAGGACAGAATATCACTTTTGTAGATTTATACCAAAAATGCATAATTT
 881 GGATATAATGAAGAAACAGTCAAATCCAAGTTTGAGGCTGGGCACAGTAGCTCATATCTGTAATCCCAGCACTTTGGGAG
 961 GCCAAGGCAGAGGATCACATGAGGTCAGGAGTTCAAGATCAGCCTGGCCAACGTGGCAAAACCCCATCTCTACGAAAAAT
1041 ACACAGATTAGCCAGGCATGGTGGAATGCACCTATAGTCCCAGCTACTTGGGAGGCTGAAGCACAAGAATCGCTTGAATC
1121 CAGGAGGCAAAAGTTGCAGTGAGCCGAGATCACACCACTGCAGTTCAGCCTGGGCAACAGACCAAGACTCTGTCTCAAAA
1201 AAAGG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agugguaacgauuucACGUUAa 5'
                         |||||| 
Target 5' aacttcacttttcccTGCAATt 3'
 618 - 639 120.00 -5.99
2 
miRNA  3' agUGGUAACGAUUUCACGUUAa 5'
            :|||  || | :||| ||| 
Target 5' taGCCA-GGC-ATGGTGGAATg 3'
 1049 - 1068 118.00 -7.90
3 
miRNA  3' agugguaaCGAUUUC-ACGUUAa 5'
                  || |||| ||||:| 
Target 5' tccaggagGCAAAAGTTGCAGTg 3'
 1119 - 1141 114.00 -12.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20076221 9 COSMIC
COSN30448689 16 COSMIC
COSN29969564 22 COSMIC
COSN30179756 26 COSMIC
COSN28672238 31 COSMIC
COSN26678353 37 COSMIC
COSN30448338 58 COSMIC
COSN31572927 96 COSMIC
COSN31593609 111 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1404588876 6 dbSNP
rs1162519451 17 dbSNP
rs1222753383 18 dbSNP
rs1281315499 22 dbSNP
rs1319682179 27 dbSNP
rs192816480 29 dbSNP
rs764788865 30 dbSNP
rs1330187636 32 dbSNP
rs991231454 40 dbSNP
rs1022845777 45 dbSNP
rs1033556918 47 dbSNP
rs576349148 47 dbSNP
rs753756411 58 dbSNP
rs757208872 80 dbSNP
rs537058322 81 dbSNP
rs1434792970 82 dbSNP
rs138058026 94 dbSNP
rs1013174430 95 dbSNP
rs116672577 96 dbSNP
rs1379036278 100 dbSNP
rs987843681 101 dbSNP
rs1160906684 120 dbSNP
rs1441020054 123 dbSNP
rs911884396 125 dbSNP
rs576081517 128 dbSNP
rs1186224553 152 dbSNP
rs943495064 157 dbSNP
rs1257770269 162 dbSNP
rs1200851897 167 dbSNP
rs1296310443 174 dbSNP
rs977854476 175 dbSNP
rs1047547 184 dbSNP
rs1039075637 187 dbSNP
rs1218775695 190 dbSNP
rs925477118 190 dbSNP
rs1283713610 203 dbSNP
rs958228255 207 dbSNP
rs1274934466 208 dbSNP
rs1342510075 216 dbSNP
rs1313659313 222 dbSNP
rs541957008 223 dbSNP
rs562252874 244 dbSNP
rs922145281 251 dbSNP
rs1300424832 253 dbSNP
rs946858497 254 dbSNP
rs1042663564 256 dbSNP
rs902725994 262 dbSNP
rs1162149178 264 dbSNP
rs1471498480 269 dbSNP
rs1248375964 272 dbSNP
rs1369839498 280 dbSNP
rs998542707 285 dbSNP
rs1188147269 287 dbSNP
rs933322741 287 dbSNP
rs1047550 288 dbSNP
rs907853647 289 dbSNP
rs1388328196 298 dbSNP
rs1447563189 299 dbSNP
rs895482356 303 dbSNP
rs1012697126 305 dbSNP
rs1208166877 317 dbSNP
rs1037785312 326 dbSNP
rs1266278056 337 dbSNP
rs1218317569 338 dbSNP
rs1022691673 343 dbSNP
rs1451446489 344 dbSNP
rs898364454 345 dbSNP
rs931113320 351 dbSNP
rs1331061135 359 dbSNP
rs1322071079 362 dbSNP
rs963223912 365 dbSNP
rs1384905700 370 dbSNP
rs1392326383 391 dbSNP
rs758214147 405 dbSNP
rs1420992954 422 dbSNP
rs1172584526 426 dbSNP
rs560022312 431 dbSNP
rs1475596440 433 dbSNP
rs1196589429 436 dbSNP
rs895041697 436 dbSNP
rs973603894 437 dbSNP
rs1453243557 438 dbSNP
rs1013435552 441 dbSNP
rs1403926754 458 dbSNP
rs1316352770 462 dbSNP
rs1260170575 480 dbSNP
rs1215559963 482 dbSNP
rs1026238921 491 dbSNP
rs1047551 495 dbSNP
rs987402504 506 dbSNP
rs911915575 507 dbSNP
rs943361087 510 dbSNP
rs1445326622 511 dbSNP
rs1032050795 516 dbSNP
rs1319137749 519 dbSNP
rs1332907182 523 dbSNP
rs974812965 538 dbSNP
rs1362334994 541 dbSNP
rs958456782 542 dbSNP
rs1424260843 543 dbSNP
rs368964744 547 dbSNP
rs1355286575 550 dbSNP
rs1479004256 562 dbSNP
rs1226383928 565 dbSNP
rs1178110814 568 dbSNP
rs1029268408 572 dbSNP
rs1240290224 583 dbSNP
rs946907957 588 dbSNP
rs1205553289 589 dbSNP
rs1442029586 597 dbSNP
rs1042918897 604 dbSNP
rs1221283829 611 dbSNP
rs924127721 612 dbSNP
rs1349252652 628 dbSNP
rs747194676 636 dbSNP
rs564036260 638 dbSNP
rs1373948855 664 dbSNP
rs1246144653 672 dbSNP
rs895495280 673 dbSNP
rs1332764020 677 dbSNP
rs1442535375 679 dbSNP
rs1358210686 689 dbSNP
rs1332009200 692 dbSNP
rs1415896983 697 dbSNP
rs1376031458 708 dbSNP
rs940701743 708 dbSNP
rs1437728219 712 dbSNP
rs973900776 725 dbSNP
rs1177850744 729 dbSNP
rs1472626507 732 dbSNP
rs920659381 732 dbSNP
rs1212689517 759 dbSNP
rs931164166 760 dbSNP
rs1466293211 770 dbSNP
rs776752241 775 dbSNP
rs531290914 779 dbSNP
rs748659486 782 dbSNP
rs1189344954 785 dbSNP
rs1308600223 786 dbSNP
rs1044169659 790 dbSNP
rs894968204 792 dbSNP
rs772617299 795 dbSNP
rs549559581 799 dbSNP
rs1416419880 803 dbSNP
rs994587575 804 dbSNP
rs1026605823 807 dbSNP
rs1417860563 809 dbSNP
rs1362366793 816 dbSNP
rs1159944005 819 dbSNP
rs770328156 820 dbSNP
rs999167235 822 dbSNP
rs1183768201 824 dbSNP
rs1475645180 825 dbSNP
rs1262967358 830 dbSNP
rs185200941 831 dbSNP
rs1489588236 837 dbSNP
rs1032520786 843 dbSNP
rs1457064083 853 dbSNP
rs1009257164 860 dbSNP
rs1215883707 862 dbSNP
rs1320544003 865 dbSNP
rs773523458 868 dbSNP
rs995908616 875 dbSNP
rs1355695029 878 dbSNP
rs529187438 892 dbSNP
rs1277393779 899 dbSNP
rs763320253 900 dbSNP
rs1029196441 901 dbSNP
rs1289334943 904 dbSNP
rs1458355076 907 dbSNP
rs954852010 909 dbSNP
rs1166962580 914 dbSNP
rs547169758 925 dbSNP
rs1320707242 926 dbSNP
rs115344679 933 dbSNP
rs1423163709 940 dbSNP
rs1015140295 941 dbSNP
rs1478966871 948 dbSNP
rs376388455 962 dbSNP
rs190197861 964 dbSNP
rs1285623136 976 dbSNP
rs1379565258 982 dbSNP
rs760285975 985 dbSNP
rs1487775808 1002 dbSNP
rs1227614182 1007 dbSNP
rs564740107 1013 dbSNP
rs973402489 1014 dbSNP
rs920571629 1016 dbSNP
rs1256957427 1027 dbSNP
rs1216607400 1030 dbSNP
rs968573815 1034 dbSNP
rs1296000935 1035 dbSNP
rs1218617116 1038 dbSNP
rs1365399251 1048 dbSNP
rs1328069663 1061 dbSNP
rs570052876 1064 dbSNP
rs962047106 1068 dbSNP
rs537449163 1070 dbSNP
rs1329509859 1071 dbSNP
rs1209426195 1072 dbSNP
rs1374038326 1076 dbSNP
rs939524173 1078 dbSNP
rs1427801986 1079 dbSNP
rs916452682 1088 dbSNP
rs1468507237 1096 dbSNP
rs949182329 1108 dbSNP
rs1196425001 1110 dbSNP
rs1481392924 1112 dbSNP
rs544328604 1113 dbSNP
rs1232241021 1121 dbSNP
rs1440777153 1124 dbSNP
rs916793031 1137 dbSNP
rs1305445884 1140 dbSNP
rs34118662 1144 dbSNP
rs1189833000 1146 dbSNP
rs1238315464 1147 dbSNP
rs948373020 1159 dbSNP
rs574259588 1164 dbSNP
rs1393428637 1165 dbSNP
rs533681296 1170 dbSNP
rs1397469991 1188 dbSNP
rs935009744 1193 dbSNP
rs1464800519 1197 dbSNP
rs1180554318 1204 dbSNP
rs1313450426 1205 dbSNP
rs1174760541 1206 dbSNP
rs1182177754 1206 dbSNP
rs1250718735 1206 dbSNP
rs1439599636 1206 dbSNP
rs535344897 1206 dbSNP
rs58956925 1206 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aguGGUAACGAUUUCACGUUAa 5'
             |||  |||::|||||||| 
Target 5' cucCCA-GGCUGGAGUGCAAUg 3'
 		2 - 22
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000361822.3 | 3UTR | UCUCCCAGGCUGGAGUGCAAUGGUGCAAUCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE38974 Chronic obstructive pulmonary disease 0.437 1.4e-2 0.431 1.6e-2 25 Click to see details
GSE21849 B cell lymphoma -0.288 6.5e-2 -0.137 2.4e-1 29 Click to see details
GSE38226 Liver fibrosis 0.307 8.8e-2 0.236 1.5e-1 21 Click to see details
GSE14794 Lymphoblastoid cells 0.127 1.2e-1 0.112 1.5e-1 90 Click to see details
GSE26953 Aortic valvular endothelial cells 0.199 1.8e-1 0.186 1.9e-1 24 Click to see details
GSE17306 Multiple myeloma -0.135 1.8e-1 0.329 1.0e-2 49 Click to see details
GSE42095 Differentiated embryonic stem cells 0.165 2.3e-1 0.255 1.2e-1 23 Click to see details
GSE19350 CNS germ cell tumors -0.206 2.6e-1 -0.231 2.4e-1 12 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.379 2.6e-1 0.000 5.0e-1 5 Click to see details
GSE28544 Breast cancer 0.131 2.7e-1 0.148 2.5e-1 24 Click to see details
GSE17498 Multiple myeloma -0.096 2.8e-1 -0.190 1.2e-1 40 Click to see details
GSE27834 Pluripotent stem cells -0.116 3.3e-1 -0.171 2.6e-1 16 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.101 3.4e-1 -0.176 2.3e-1 20 Click to see details
GSE21687 Ependynoma primary tumors 0.047 3.6e-1 -0.032 4.0e-1 64 Click to see details
GSE28260 Renal cortex and medulla -0.004 4.9e-1 -0.034 4.6e-1 13 Click to see details
GSE32688 Pancreatic cancer -0.002 5.0e-1 -0.155 2.0e-1 32 Click to see details
GSE32688 Pancreatic cancer -0.002 5.0e-1 -0.155 2.0e-1 32 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
255 hsa-miR-367-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055315 DUSP5 dual specificity phosphatase 5 2 8
MIRT055791 PLEKHA1 pleckstrin homology domain containing A1 2 12
MIRT057114 DDIT4 DNA damage inducible transcript 4 2 4
MIRT059663 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT059926 ZDHHC5 zinc finger DHHC-type containing 5 2 2
MIRT061610 BTG2 BTG anti-proliferation factor 2 2 6
MIRT066478 HMGA2 high mobility group AT-hook 2 2 2
MIRT069388 ZFYVE21 zinc finger FYVE-type containing 21 2 2
MIRT069972 GEMIN2 gem nuclear organelle associated protein 2 2 2
MIRT074764 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT076199 GID4 GID complex subunit 4 homolog 2 6
MIRT077512 UBE2Z ubiquitin conjugating enzyme E2 Z 2 4
MIRT077903 TOB1 transducer of ERBB2, 1 2 6
MIRT082250 MED29 mediator complex subunit 29 2 4
MIRT082434 CIC capicua transcriptional repressor 2 6
MIRT082474 PPP1R37 protein phosphatase 1 regulatory subunit 37 2 2
MIRT082778 ZNF264 zinc finger protein 264 2 2
MIRT084533 BCL2L11 BCL2 like 11 2 8
MIRT085309 UBXN4 UBX domain protein 4 2 8
MIRT086365 SSFA2 sperm specific antigen 2 2 8
MIRT087455 NF2 neurofibromin 2 2 2
MIRT088865 FOXN2 forkhead box N2 2 12
MIRT092185 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 2 6
MIRT092326 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 6
MIRT093533 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096935 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 8
MIRT097026 MAP1B microtubule associated protein 1B 2 4
MIRT099137 MYLIP myosin regulatory light chain interacting protein 2 6
MIRT099905 SOX4 SRY-box 4 2 12
MIRT102289 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT102507 KLHDC10 kelch domain containing 10 2 2
MIRT102891 INSIG1 insulin induced gene 1 2 2
MIRT109188 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT124567 PRRC2B proline rich coiled-coil 2B 2 2
MIRT135568 SPRYD4 SPRY domain containing 4 2 2
MIRT161135 SLC25A36 solute carrier family 25 member 36 2 6
MIRT163995 KIAA1109 KIAA1109 2 4
MIRT164689 RNF4 ring finger protein 4 2 2
MIRT167705 HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2 8
MIRT178956 USP28 ubiquitin specific peptidase 28 2 2
MIRT185717 ARNTL2 aryl hydrocarbon receptor nuclear translocator like 2 2 2
MIRT186264 TCEB3 elongin A 2 2
MIRT186537 TWF1 twinfilin actin binding protein 1 2 4
MIRT186628 COX20 COX20, cytochrome c oxidase assembly factor 2 8
MIRT189373 TXLNA taxilin alpha 2 4
MIRT197013 EIF1 eukaryotic translation initiation factor 1 2 10
MIRT206437 YIPF4 Yip1 domain family member 4 2 2
MIRT211228 FGF2 fibroblast growth factor 2 2 10
MIRT214529 C5ORF24 chromosome 5 open reading frame 24 2 2
MIRT216034 IL6ST interleukin 6 signal transducer 2 10
MIRT218084 TULP4 tubby like protein 4 2 2
MIRT242418 CCDC113 coiled-coil domain containing 113 2 2
MIRT243162 SOX11 SRY-box 11 2 2
MIRT250943 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT253350 ZNF417 zinc finger protein 417 2 2
MIRT271968 ARF1 ADP ribosylation factor 1 2 2
MIRT273214 ZNF695 zinc finger protein 695 2 4
MIRT296114 SLC12A5 solute carrier family 12 member 5 2 2
MIRT301711 TEF TEF, PAR bZIP transcription factor 2 2
MIRT316477 ARID1B AT-rich interaction domain 1B 2 6
MIRT322174 CLN8 CLN8, transmembrane ER and ERGIC protein 2 4
MIRT341538 CNIH1 cornichon family AMPA receptor auxiliary protein 1 2 6
MIRT356062 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT443579 PPIC peptidylprolyl isomerase C 2 2
MIRT448825 FKBP1A FK506 binding protein 1A 2 4
MIRT451494 FOPNL FGFR1OP N-terminal like 2 2
MIRT452694 MDM2 MDM2 proto-oncogene 2 2
MIRT453167 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT454588 SLC33A1 solute carrier family 33 member 1 2 4
MIRT455794 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT456010 CYP2C19 cytochrome P450 family 2 subfamily C member 19 2 2
MIRT456044 KIAA1586 KIAA1586 2 2
MIRT456763 TMEM239 transmembrane protein 239 2 4
MIRT458068 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT459230 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT459534 MFF mitochondrial fission factor 2 6
MIRT459759 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT460236 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT461104 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT462924 ZNRF3 zinc and ring finger 3 2 2
MIRT463476 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463516 ZBTB8B zinc finger and BTB domain containing 8B 2 4
MIRT465503 TOR1B torsin family 1 member B 2 2
MIRT469525 RBFOX2 RNA binding protein, fox-1 homolog 2 2 8
MIRT470079 PTGES2 prostaglandin E synthase 2 2 2
MIRT471581 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT473451 MCOLN2 mucolipin 2 2 8
MIRT475882 H3F3C H3 histone family member 3C 2 10
MIRT475915 H3F3B H3 histone family member 3B 2 8
MIRT476195 GOLGA8A golgin A8 family member A 2 10
MIRT476318 GM2A GM2 ganglioside activator 2 2
MIRT476676 FUT11 fucosyltransferase 11 2 10
MIRT478368 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT479545 CDC5L cell division cycle 5 like 2 2
MIRT481024 BAZ2B bromodomain adjacent to zinc finger domain 2B 2 2
MIRT491009 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT493168 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 2
MIRT494345 CASKIN1 CASK interacting protein 1 2 2
MIRT499087 ZDHHC21 zinc finger DHHC-type containing 21 2 6
MIRT500029 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501298 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 4
MIRT503124 BCL11B B-cell CLL/lymphoma 11B 2 8
MIRT503301 GTF2A1 general transcription factor IIA subunit 1 2 6
MIRT504328 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504471 EID2B EP300 interacting inhibitor of differentiation 2B 2 2
MIRT504655 RPL9 ribosomal protein L9 2 6
MIRT505331 TMF1 TATA element modulatory factor 1 2 8
MIRT505732 SERTAD3 SERTA domain containing 3 2 4
MIRT505827 RSBN1 round spermatid basic protein 1 2 8
MIRT506004 PURG purine rich element binding protein G 2 8
MIRT506308 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT506806 KLHL15 kelch like family member 15 2 6
MIRT507119 GOLGA8B golgin A8 family member B 2 6
MIRT507353 FAM129A family with sequence similarity 129 member A 2 6
MIRT507591 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT507674 CPEB4 cytoplasmic polyadenylation element binding protein 4 2 4
MIRT507703 CNOT2 CCR4-NOT transcription complex subunit 2 2 8
MIRT508012 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT510439 ZIC5 Zic family member 5 2 6
MIRT510539 XKR7 XK related 7 2 4
MIRT510600 TPPP tubulin polymerization promoting protein 2 6
MIRT511060 NRAS NRAS proto-oncogene, GTPase 2 4
MIRT511855 GOLGA8J golgin A8 family member J 2 6
MIRT511865 GOLGA8I golgin A8 family member I, pseudogene 1 3
MIRT512570 CTDSPL CTD small phosphatase like 2 2
MIRT512708 ZNF134 zinc finger protein 134 2 6
MIRT513177 MOAP1 modulator of apoptosis 1 2 6
MIRT513783 PAWR pro-apoptotic WT1 regulator 2 6
MIRT515099 IRGQ immunity related GTPase Q 2 2
MIRT515481 INCENP inner centromere protein 2 4
MIRT517416 BMP8A bone morphogenetic protein 8a 2 2
MIRT518754 C1orf35 chromosome 1 open reading frame 35 2 2
MIRT519780 ZNF354B zinc finger protein 354B 2 4
MIRT519865 ZFP62 ZFP62 zinc finger protein 2 6
MIRT520510 TRAM2 translocation associated membrane protein 2 2 6
MIRT521068 SLC25A32 solute carrier family 25 member 32 2 6
MIRT526912 ZNF772 zinc finger protein 772 2 6
MIRT527134 GULP1 GULP, engulfment adaptor PTB domain containing 1 2 2
MIRT527867 SLC39A14 solute carrier family 39 member 14 2 2
MIRT528404 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT532956 ZNF24 zinc finger protein 24 2 4
MIRT533021 ZFC3H1 zinc finger C3H1-type containing 2 4
MIRT533191 WASL Wiskott-Aldrich syndrome like 2 6
MIRT534191 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534961 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2 4
MIRT536396 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT537046 GRAMD4 GRAM domain containing 4 2 2
MIRT537125 GOLGA3 golgin A3 2 4
MIRT537183 GFPT2 glutamine-fructose-6-phosphate transaminase 2 2 4
MIRT537652 ERGIC2 ERGIC and golgi 2 2 4
MIRT538632 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT539231 ANP32E acidic nuclear phosphoprotein 32 family member E 2 6
MIRT540099 NPY4R neuropeptide Y receptor Y4 2 2
MIRT540998 ZNF460 zinc finger protein 460 2 4
MIRT541468 AURKA aurora kinase A 2 2
MIRT542680 SESN3 sestrin 3 2 2
MIRT542757 PRRG4 proline rich and Gla domain 4 2 2
MIRT542863 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT542925 HOXC8 homeobox C8 2 2
MIRT543747 SZRD1 SUZ RNA binding domain containing 1 2 2
MIRT544404 ZSCAN12 zinc finger and SCAN domain containing 12 2 2
MIRT544583 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT544662 MED19 mediator complex subunit 19 2 2
MIRT545251 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT545261 TRIM36 tripartite motif containing 36 2 4
MIRT545744 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT545999 WDR81 WD repeat domain 81 2 2
MIRT546038 VPS4B vacuolar protein sorting 4 homolog B 2 2
MIRT547170 PDZD8 PDZ domain containing 8 2 2
MIRT547273 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT547729 KIF5B kinesin family member 5B 2 2
MIRT548127 GATA6 GATA binding protein 6 2 2
MIRT548203 FNIP1 folliculin interacting protein 1 2 2
MIRT548756 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT549641 ZNF75A zinc finger protein 75a 2 2
MIRT549684 ZNF598 zinc finger protein 598 2 2
MIRT550197 MRO maestro 2 2
MIRT550340 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT550536 MYZAP myocardial zonula adherens protein 2 2
MIRT550975 TOR4A torsin family 4 member A 2 2
MIRT551221 CIDEC cell death inducing DFFA like effector c 2 2
MIRT551355 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT551571 LETM1 leucine zipper and EF-hand containing transmembrane protein 1 2 2
MIRT552277 RAB3D RAB3D, member RAS oncogene family 2 2
MIRT552661 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT553081 UCK2 uridine-cytidine kinase 2 2 2
MIRT553753 TBC1D8 TBC1 domain family member 8 2 2
MIRT554030 SPCS3 signal peptidase complex subunit 3 2 2
MIRT554099 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT554155 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT554815 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT555522 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT555597 PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma 2 2
MIRT555632 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 4
MIRT555679 PGAM4 phosphoglycerate mutase family member 4 2 4
MIRT555827 PAX9 paired box 9 2 2
MIRT555868 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT555939 NUP43 nucleoporin 43 2 2
MIRT555994 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT556340 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556432 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT556585 LHFPL2 LHFPL tetraspan subfamily member 2 2 4
MIRT556801 KIAA1958 KIAA1958 2 2
MIRT558047 EXOC5 exocyst complex component 5 2 2
MIRT558697 CLTA clathrin light chain A 2 2
MIRT559191 BMPR1A bone morphogenetic protein receptor type 1A 2 4
MIRT559639 AKAP10 A-kinase anchoring protein 10 2 2
MIRT559707 AEN apoptosis enhancing nuclease 2 2
MIRT560673 SRFBP1 serum response factor binding protein 1 2 2
MIRT560990 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT562170 HOXA13 homeobox A13 2 2
MIRT562275 GNAQ G protein subunit alpha q 2 2
MIRT563624 ZNF277 zinc finger protein 277 2 2
MIRT563815 FMN1 formin 1 2 2
MIRT564096 TLR3 toll like receptor 3 2 2
MIRT565320 TMEM41A transmembrane protein 41A 2 2
MIRT565986 RNF44 ring finger protein 44 2 2
MIRT566047 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT568236 C11orf24 chromosome 11 open reading frame 24 2 2
MIRT568310 BAK1 BCL2 antagonist/killer 1 2 2
MIRT572376 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT574822 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 2
MIRT609212 PELP1 proline, glutamate and leucine rich protein 1 2 2
MIRT616217 RBM27 RNA binding motif protein 27 2 2
MIRT629087 FASLG Fas ligand 2 2
MIRT632124 FKBP9 FK506 binding protein 9 2 2
MIRT632576 POLQ DNA polymerase theta 2 2
MIRT634799 ENTHD1 ENTH domain containing 1 2 2
MIRT636553 ESRP1 epithelial splicing regulatory protein 1 2 2
MIRT640977 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT653875 SH2B3 SH2B adaptor protein 3 2 2
MIRT655598 OTUD7B OTU deubiquitinase 7B 2 2
MIRT659764 CCDC171 coiled-coil domain containing 171 2 2
MIRT660744 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT681037 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT682305 RBM28 RNA binding motif protein 28 2 2
MIRT682573 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT686217 ZNF267 zinc finger protein 267 2 2
MIRT687209 PLXNA3 plexin A3 2 2
MIRT690630 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT692419 AGMAT agmatinase 2 2
MIRT694437 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT700725 PNO1 partner of NOB1 homolog 2 2
MIRT701549 NARF nuclear prelamin A recognition factor 2 2
MIRT704379 DAND5 DAN domain BMP antagonist family member 5 2 2
MIRT707935 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT709939 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT711371 MED7 mediator complex subunit 7 2 2
MIRT712327 PER2 period circadian clock 2 2 2
MIRT714515 SHE Src homology 2 domain containing E 2 2
MIRT715520 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT724294 OSMR oncostatin M receptor 2 2
MIRT725358 MUC21 mucin 21, cell surface associated 2 2
MIRT732242 KLF4 Kruppel like factor 4 3 1
MIRT735384 SPAG5 sperm associated antigen 5 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-367 Medpor NULL NULL Microarray osteoblast-like cells line (MG-63) 18408260 2008 up-regulated
miR-367 Activin A NULL 229455 Quantitative real-time PCR Human embryonic stem (hES) cells 19885849 2010 up-regulated
miR-367 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells CLY cells 20955366 2011 down-regulated
miR-367 Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miR-367 Paclitaxel approved 36314 Microarray Ovarian cancer cell lines 24220856 2014 up-regulated
miR-367 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-367 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Siop Treatment Protocol sensitive High Nephroblastoma tissue
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved resistant High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved sensitive High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-367-3p Mitoxantrone 4212 NSC279836 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Sorafenib 216239 NSC747971 approved sensitive Low Hepatocellular Carcinoma cell line (SKhep1, HA22T)
hsa-miR-367-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-367-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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