miRTarBase - #MIRT564661


—
pre-miRNA Information
pre-miRNA hsa-mir-3622a   
Genomic Coordinates chr8: 27701677 - 27701759
Description Homo sapiens miR-3622a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3622a-5p
Sequence 14| CAGGCACGGGAGCUCAGGUGAG |35
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 8 + 27701691 29233923 MiREDiBase
A-to-I 6 8 + 27701695 29233923 MiREDiBase
A-to-I 16 8 + 27701705 28550310, 29233923 MiREDiBase
A-to-I 21 8 + 27701710 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs551845360 1 dbSNP
rs946438979 3 dbSNP
rs1044808718 7 dbSNP
rs66683138 8 dbSNP
rs1157333896 10 dbSNP
rs1439657384 12 dbSNP
rs530939348 17 dbSNP
rs1232922758 20 dbSNP
rs1448152954 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ZNF449   
Synonyms ZSCAN19
Description zinc finger protein 449
Transcript NM_152695   
Expression
Putative miRNA Targets on ZNF449
3'UTR of ZNF449
(miRNA target sites are highlighted)		 
>ZNF449|NM_152695|3'UTR
   1 GAATTGCTAAGGGAAACAGGTCTTACACAAATTGACACTAACTCAAAAAAAATCTTAACCTGCAGCAGGCTGTTTGTCTT
  81 GGAAGCTTTTGTTTGAGCTTATAAGAACATAGACAGCTTTTTTTTTTACTAGTTTTAAAACCCATCTTCCAAGGTATATG
 161 AATTCTAGAGTATTTATCTACTCCTGTGATTTTCTTAGATTTGATTTCTTCTGTCTGCACAACTCTTCTTTTTTTAATTA
 241 CAATGAAAAATTTTGTGTTCCAAGGCAACTGTATCATAGGTGTAAACATAAAGCATATAAATTATGACAATCCTTTTAGA
 321 GGTAGGGTCAATATAGTGGATAAACCTGTCTATCAGACGTATTGATTATAGCAGTACTATAGTTATTCTGCTGTCATTAT
 401 TAAAGATGATTATATTCATTCAAAGCTTTAGATGTGTCCCATGTGGCAAGAAAGGAGACAGTGAATTTTGTCAAACAATA
 481 AAAATGTGTCAGGAACACAAGGATGAAGGGGATGTCATTTGCCTGGTAAGAACTGGGTTATTTCCACTGAAATTTGTTAT
 561 GTTTAAGGAAATTAAGATTTTAAGCTTGAAATTATACAAGCAGAATCTAATTTAATTTTGATTGACTGAAGAACCAGGGT
 641 CTTTTGCTCTCCTTTGGTATTTCACTCTCCTTTGGTATTCAATCATGTGTCTTTTAGTGCTTTTTAAAATTTTACCCATT
 721 CTTTAATTCAGCATCTCCCTATGTATGTGTCATAGAATACTTAGTTCTGCTAGATATTCTGCAAATATATTTGGGAATTA
 801 CTTCCTGCTGTTTCGCCTTCTTAGGTTCATAGTACACATCAGCATATGAGAATCTCTGAGAGGTCCTCTAGAAAGGAGAG
 881 AAAAAGCACCTCTTTTGGCTCAATGTTTTCCAAACTTATTTGACCCCAAAACCTTTTTCATATACCCAATAATAAGCTAC
 961 AGAACTAATATTCTGCAAATGTCTCTTGGAACACACTGCCTTAAACAGATATTTCTATAGCTGTCAGTATAGTTATGTTG
1041 CTCCCAAGCCTAGTTATCTCCAGTTGTTTTAAGGGTGTTATGAAAAATTCTTAAAATATATATGAATTTGTGTAACACAC
1121 ACAGAGACACACACACATACTACTTTAAGGGGGTGAGGATCATTAATTCAGATAATTTTTAAGTTTCCTAGTGATTCTCA
1201 ATCTCTTTGAATTTTACTTACATTTACACACACACGCACACACATATGTATATACACATATCATTTTAAGAAGCTGAGGA
1281 TCACTAATTCAGATAATGTATAAGTTTCCCAGTGATTCTCAACCTCTTTGAATTTTACTTATAATTACATACACACACAC
1361 ACTGCTACTTATATAAATGTTCTCATGTAATCATGGTAACAGCTCAAATTCCCAAAGCAAGGGAAGACTTCTCATTGTCA
1441 GTTAAACCTGTTAAAACATGAAAATATTCATTGAGCCTAGTTCCTTGTTATAAAATACAAGAAATAAGACATTCAGGCAT
1521 TTTCCCTTTATGAAGATGTTCAGTCATCCTTTCCTTGAACTACAATTAGGAAAAGTATATGTCTTTATTCCATTGAAGTT
1601 CTCGAGAGTGATATAAATACTTTGGGGGGTATCTACTATGTGCCTAACTAGTCCTGTTCTAGGCTTAGTGGAAGCTAGTA
1681 AAGAAATATAATTCATGGATCAGGCTCATAAAGATTTTATAATATTTTTAGTTAAACAAGAGTTGGGAAACAGGTGGAGA
1761 ATAATGCAAGAGAGTTTGTAATTAAGTGCCAATTATACCAATTGCTAGACCCAGGATGTATCTTTAATTCTTGTCATCCA
1841 GGTCAACATATGATGCTGCTATAAGTCTGGGGCTCAAATTGATATCCCAGTAGCAATAAACATATAATATAGGAGGAGTC
1921 TGAATGTAGAGATGAAAAATACAGAATGTAATGGCTTCTCTTTTCTCTCTTGTGGAATTGCATTCAAACCAGAACAGTGC
2001 CTTAGAATGGATGTGCCCAACTGCTCTGTATTTATGCAATATTTGAATAAAGCGGAAATGTATGTGCTCTTCCTGCTTCA
2081 CTTGCACTAATTAATTATTTGAACAACTTAGAGCTTCTTCCCTGAACAGTGGCAACAAGCATGGCAATTGACTCTGTCCT
2161 CATCCCAAGTTGGAATCGCTTTTCTCTCTGCAACCATGGCACTGTGATTATGCATCATTTTTAGCATTTAATACAGTCCA
2241 TTTTTGGCTAGTAGGGTTAGTTGCAATCATAATATGAGTTGCATCCTCCCTCTCATTTATATCAAATATACTTGACTAGA
2321 TTTTTACAAGTTAGAGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaGUGGACUCGAGGGCACGGAc 5'
            :|:|| | ||  :|||||| 
Target 5' ggTATCT-A-CT-ATGTGCCTa 3'
 1628 - 1646 129.00 -13.10
2 
miRNA  3' gagUGGACUCGAGGGCACGGAc 5'
             ||| || |    |||||| 
Target 5' caaACCAGAACA---GTGCCTt 3'
 1985 - 2003 123.00 -11.40
3 
miRNA  3' gaguggacucgAGGGCACGGAc 5'
                     || :|||:|| 
Target 5' ttggtattcaaTCATGTGTCTt 3'
 672 - 693 115.00 -10.70
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1380391071 5 dbSNP
rs971234530 13 dbSNP
rs978230868 21 dbSNP
rs1160589330 22 dbSNP
rs782187900 25 dbSNP
rs782424987 40 dbSNP
rs1256120221 45 dbSNP
rs782682913 45 dbSNP
rs782816978 45 dbSNP
rs923921953 58 dbSNP
rs572223533 70 dbSNP
rs1354616738 73 dbSNP
rs1288282691 81 dbSNP
rs1242651828 90 dbSNP
rs936715704 110 dbSNP
rs1311989852 115 dbSNP
rs1357134363 118 dbSNP
rs1396527684 118 dbSNP
rs1296052609 145 dbSNP
rs1399036674 155 dbSNP
rs1360720862 158 dbSNP
rs1290234969 159 dbSNP
rs1455977899 163 dbSNP
rs61227378 166 dbSNP
rs911480093 179 dbSNP
rs1476435629 196 dbSNP
rs1421955769 205 dbSNP
rs1193337318 226 dbSNP
rs1488759614 233 dbSNP
rs942831632 238 dbSNP
rs1041213474 257 dbSNP
rs901562945 266 dbSNP
rs1208271495 281 dbSNP
rs782621456 283 dbSNP
rs1266036701 289 dbSNP
rs1245443902 296 dbSNP
rs1336793953 304 dbSNP
rs781862331 305 dbSNP
rs58073587 311 dbSNP
rs1340873365 316 dbSNP
rs782200786 332 dbSNP
rs181623525 345 dbSNP
rs1389396684 355 dbSNP
rs1293548104 359 dbSNP
rs1005898493 360 dbSNP
rs1398691718 394 dbSNP
rs1170558075 403 dbSNP
rs1478384302 419 dbSNP
rs186249743 424 dbSNP
rs34493055 438 dbSNP
rs782557876 502 dbSNP
rs895083400 503 dbSNP
rs1268172646 531 dbSNP
rs1215590534 536 dbSNP
rs1456473778 538 dbSNP
rs1012060613 544 dbSNP
rs1256133638 546 dbSNP
rs782314908 555 dbSNP
rs1197921102 558 dbSNP
rs1318417087 583 dbSNP
rs1271650229 600 dbSNP
rs1025217662 610 dbSNP
rs970613091 613 dbSNP
rs1330102012 616 dbSNP
rs1301401386 635 dbSNP
rs1442521523 639 dbSNP
rs1373993515 641 dbSNP
rs1331333087 642 dbSNP
rs1466537082 646 dbSNP
rs1399094015 656 dbSNP
rs978580950 667 dbSNP
rs1171134237 668 dbSNP
rs1031117293 683 dbSNP
rs1378468442 685 dbSNP
rs1195709399 686 dbSNP
rs781863320 727 dbSNP
rs145237468 732 dbSNP
rs989441467 739 dbSNP
rs1237635216 742 dbSNP
rs1177941800 746 dbSNP
rs1438268526 754 dbSNP
rs782297453 758 dbSNP
rs942967211 778 dbSNP
rs1274888067 785 dbSNP
rs1198477680 788 dbSNP
rs868916621 815 dbSNP
rs1280663691 816 dbSNP
rs1236030566 821 dbSNP
rs782257926 829 dbSNP
rs1307817870 838 dbSNP
rs1448191677 861 dbSNP
rs1338008501 881 dbSNP
rs782405726 901 dbSNP
rs782001850 906 dbSNP
rs1395859553 915 dbSNP
rs1403340677 917 dbSNP
rs1175836455 934 dbSNP
rs1418023488 944 dbSNP
rs1379782276 955 dbSNP
rs1159278639 979 dbSNP
rs557867152 987 dbSNP
rs1470491380 992 dbSNP
rs1047901538 1006 dbSNP
rs1185308797 1010 dbSNP
rs1441693179 1030 dbSNP
rs886192532 1033 dbSNP
rs1212593170 1037 dbSNP
rs1350984342 1038 dbSNP
rs1284724711 1044 dbSNP
rs1223890796 1064 dbSNP
rs1352185468 1071 dbSNP
rs1283002889 1074 dbSNP
rs1244694845 1081 dbSNP
rs1341450438 1088 dbSNP
rs60061278 1089 dbSNP
rs1315110365 1094 dbSNP
rs1398411665 1099 dbSNP
rs1360092172 1113 dbSNP
rs1298998697 1116 dbSNP
rs1402578269 1132 dbSNP
rs941654625 1147 dbSNP
rs868973497 1192 dbSNP
rs1411707107 1193 dbSNP
rs1161392586 1202 dbSNP
rs1472390437 1206 dbSNP
rs1418331380 1214 dbSNP
rs1037385945 1222 dbSNP
rs1487167719 1226 dbSNP
rs1262079481 1227 dbSNP
rs1216049705 1234 dbSNP
rs1448295263 1236 dbSNP
rs1209783678 1237 dbSNP
rs1287049501 1237 dbSNP
rs190614636 1244 dbSNP
rs1295535822 1255 dbSNP
rs1217232780 1260 dbSNP
rs1340276299 1266 dbSNP
rs1271055683 1290 dbSNP
rs1433154349 1300 dbSNP
rs182001456 1303 dbSNP
rs1348214504 1321 dbSNP
rs1322916304 1329 dbSNP
rs1404722679 1339 dbSNP
rs1395177459 1342 dbSNP
rs1166979956 1348 dbSNP
rs1012153621 1351 dbSNP
rs1422650987 1351 dbSNP
rs199730991 1351 dbSNP
rs782269906 1351 dbSNP
rs1186747976 1352 dbSNP
rs1476157300 1353 dbSNP
rs1046351069 1355 dbSNP
rs577851561 1359 dbSNP
rs1468516598 1382 dbSNP
rs999372030 1407 dbSNP
rs1275657040 1421 dbSNP
rs556670410 1446 dbSNP
rs1197292307 1448 dbSNP
rs781965785 1457 dbSNP
rs1274078263 1459 dbSNP
rs1216569445 1470 dbSNP
rs958132152 1474 dbSNP
rs1365702152 1478 dbSNP
rs1274451667 1484 dbSNP
rs782342333 1495 dbSNP
rs782074845 1498 dbSNP
rs1373269677 1503 dbSNP
rs1327920952 1518 dbSNP
rs781940545 1532 dbSNP
rs371713331 1539 dbSNP
rs1170822800 1549 dbSNP
rs1411333462 1552 dbSNP
rs1422671762 1564 dbSNP
rs1190250947 1569 dbSNP
rs1454382243 1584 dbSNP
rs1254332896 1594 dbSNP
rs1177324277 1600 dbSNP
rs375711693 1605 dbSNP
rs782200731 1607 dbSNP
rs1233845583 1612 dbSNP
rs1207110734 1613 dbSNP
rs1310783754 1616 dbSNP
rs1278255411 1619 dbSNP
rs1235291015 1624 dbSNP
rs977405493 1626 dbSNP
rs1350150311 1627 dbSNP
rs1307105613 1643 dbSNP
rs1444503566 1653 dbSNP
rs1372480770 1655 dbSNP
rs1298651145 1662 dbSNP
rs1444178592 1667 dbSNP
rs1357203015 1675 dbSNP
rs782320112 1689 dbSNP
rs1434884371 1691 dbSNP
rs1396382735 1694 dbSNP
rs6635040 1701 dbSNP
rs782156513 1705 dbSNP
rs374989657 1709 dbSNP
rs951591470 1711 dbSNP
rs782020476 1715 dbSNP
rs1482518997 1717 dbSNP
rs1237195907 1723 dbSNP
rs1211882845 1724 dbSNP
rs782139865 1740 dbSNP
rs1239569984 1768 dbSNP
rs1317571756 1782 dbSNP
rs1307692514 1790 dbSNP
rs1225392485 1793 dbSNP
rs1376710818 1807 dbSNP
rs1311989167 1809 dbSNP
rs1376939209 1815 dbSNP
rs1295936016 1817 dbSNP
rs782757637 1820 dbSNP
rs1452498100 1822 dbSNP
rs1363869001 1851 dbSNP
rs1161919503 1856 dbSNP
rs782794172 1867 dbSNP
rs1422522784 1871 dbSNP
rs1417621958 1872 dbSNP
rs781837804 1886 dbSNP
rs1037481103 1891 dbSNP
rs1476374158 1894 dbSNP
rs916249221 1902 dbSNP
rs781878386 1903 dbSNP
rs1216150078 1905 dbSNP
rs1046708649 1931 dbSNP
rs1262504325 1935 dbSNP
rs782120830 1952 dbSNP
rs1217885141 1956 dbSNP
rs1319809202 1973 dbSNP
rs906450424 1982 dbSNP
rs868907782 2021 dbSNP
rs1292561973 2044 dbSNP
rs1233723308 2054 dbSNP
rs369968805 2055 dbSNP
rs1275983671 2063 dbSNP
rs1046642 2064 dbSNP
rs1385067990 2087 dbSNP
rs893668363 2091 dbSNP
rs782471510 2105 dbSNP
rs1394447423 2108 dbSNP
rs782460805 2113 dbSNP
rs782567939 2116 dbSNP
rs1018352529 2121 dbSNP
rs781909025 2133 dbSNP
rs964005027 2143 dbSNP
rs1421934410 2144 dbSNP
rs1192756998 2152 dbSNP
rs1429285072 2160 dbSNP
rs1263978284 2161 dbSNP
rs1189582105 2168 dbSNP
rs1488183717 2169 dbSNP
rs1272489926 2171 dbSNP
rs782533774 2178 dbSNP
rs1214179777 2181 dbSNP
rs1336763532 2191 dbSNP
rs998200768 2212 dbSNP
rs1226302841 2225 dbSNP
rs1030303777 2232 dbSNP
rs1326621386 2240 dbSNP
rs1297223620 2258 dbSNP
rs1384590100 2277 dbSNP
rs951675699 2286 dbSNP
rs1369535157 2293 dbSNP
rs1327167004 2317 dbSNP
rs782700364 2318 dbSNP
rs1463468291 2319 dbSNP
rs1398628111 2325 dbSNP
rs1167674143 2337 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gaGUGGACUCGAGGGCACGGAc 5'
            :|:|| | ||  :|||||| 
Target 5' --UAUCU-A-CU-AUGUGCCUa 3'
 		1 - 17
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000339249.4 | 3UTR | UAUCUACUAUGUGCCUAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
THCA -0.259 0.27 -0.143 0.37 8 Click to see details
THCA -0.259 0.27 -0.143 0.37 8 Click to see details
THCA -0.259 0.27 -0.143 0.37 8 Click to see details
THCA -0.259 0.27 -0.143 0.37 8 Click to see details
THCA -0.259 0.27 -0.143 0.37 8 Click to see details
THCA -0.259 0.27 -0.143 0.37 8 Click to see details
THCA -0.259 0.27 -0.143 0.37 8 Click to see details
61 hsa-miR-3622a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT166678 ZSWIM6 zinc finger SWIM-type containing 6 2 2
MIRT452081 ATP6V0B ATPase H+ transporting V0 subunit b 2 2
MIRT457039 S1PR3 sphingosine-1-phosphate receptor 3 2 2
MIRT471975 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT474065 LMNB2 lamin B2 2 2
MIRT475862 H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase 2 2
MIRT476191 GOLGA8A golgin A8 family member A 2 2
MIRT476521 GABRB1 gamma-aminobutyric acid type A receptor beta1 subunit 2 2
MIRT483046 C15orf52 chromosome 15 open reading frame 52 2 4
MIRT495541 EIF3H eukaryotic translation initiation factor 3 subunit H 2 2
MIRT495892 CLOCK clock circadian regulator 2 2
MIRT495992 LTBP2 latent transforming growth factor beta binding protein 2 2 2
MIRT496001 EMP1 epithelial membrane protein 1 2 2
MIRT496208 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 2 2
MIRT496427 ACTRT3 actin related protein T3 2 2
MIRT496438 ZNF704 zinc finger protein 704 2 2
MIRT496473 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT496555 TBX15 T-box 15 2 2
MIRT497202 CECR1 adenosine deaminase 2 2 2
MIRT507632 CREBZF CREB/ATF bZIP transcription factor 2 2
MIRT513377 MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 2 2
MIRT523460 GOLGA8J golgin A8 family member J 2 2
MIRT523465 GOLGA8I golgin A8 family member I, pseudogene 1 1
MIRT526049 GMDS GDP-mannose 4,6-dehydratase 2 2
MIRT533122 YIPF4 Yip1 domain family member 4 2 2
MIRT534183 SLC8A1 solute carrier family 8 member A1 2 2
MIRT556618 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT563361 WHSC1 nuclear receptor binding SET domain protein 2 2 2
MIRT563868 FAM206A family with sequence similarity 206 member A 2 2
MIRT564360 PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2 2
MIRT564661 ZNF449 zinc finger protein 449 2 2
MIRT564805 ZBTB33 zinc finger and BTB domain containing 33 2 2
MIRT564867 ZBED3 zinc finger BED-type containing 3 2 2
MIRT565340 TMEM104 transmembrane protein 104 2 2
MIRT566439 PHF16 jade family PHD finger 3 2 2
MIRT567587 FCHSD2 FCH and double SH3 domains 2 2 2
MIRT569597 C3orf62 chromosome 3 open reading frame 62 2 2
MIRT569700 FMNL3 formin like 3 2 2
MIRT575957 Nanos1 nanos homolog 1 (Drosophila) 2 3
MIRT576516 Slc35e2 solute carrier family 35, member E2 2 2
MIRT608480 RRP36 ribosomal RNA processing 36 2 2
MIRT614335 NANOS1 nanos C2HC-type zinc finger 1 2 3
MIRT630816 ATAT1 alpha tubulin acetyltransferase 1 2 4
MIRT631708 C1QTNF6 C1q and TNF related 6 2 2
MIRT632369 SRRD SRR1 domain containing 2 2
MIRT633471 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT634478 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 2
MIRT667336 MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like 2 2
MIRT667654 LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2 2
MIRT671046 SS18 SS18, nBAF chromatin remodeling complex subunit 2 2
MIRT672823 VEZT vezatin, adherens junctions transmembrane protein 2 2
MIRT673049 SGPL1 sphingosine-1-phosphate lyase 1 2 2
MIRT673435 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT676096 DPP9 dipeptidyl peptidase 9 2 2
MIRT678059 RPL7L1 ribosomal protein L7 like 1 2 2
MIRT679783 GOLGA2 golgin A2 2 2
MIRT684219 C9orf64 chromosome 9 open reading frame 64 2 2
MIRT697642 WRN Werner syndrome RecQ like helicase 2 2
MIRT706595 C1RL complement C1r subcomponent like 2 2
MIRT706603 CCS copper chaperone for superoxide dismutase 2 2
MIRT717647 HLX H2.0 like homeobox 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-3622a Doxorubicin 31703 NSC123127 approved resistant High Hepatocellular Carcinoma cell line (HepG2)
hsa-mir-3622a Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-miR-3622a-5p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-3622a-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-3622a-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-3622a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3622a-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-3622a-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-3622a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)
hsa-miR-3622a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3622a-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-3622a-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-3622a-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (Panc1-GR3)
hsa-miR-3622a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

Error report submission