miRTarBase - #MIRT566480


—
pre-miRNA Information
pre-miRNA hsa-mir-4464   
Genomic Coordinates chr6: 90312742 - 90312833
Description Homo sapiens miR-4464 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4464
Sequence 12| AAGGUUUGGAUAGAUGCAAUA |32
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 12 6 + 90312764 29233923 MiREDiBase
A-to-I 14 6 + 90312766 29233923 MiREDiBase
A-to-I 19 6 + 90312771 29233923 MiREDiBase
A-to-I 21 6 + 90312773 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1240632245 2 dbSNP
rs34899210 2 dbSNP
rs1003034046 13 dbSNP
rs1475351324 14 dbSNP
rs1257582329 17 dbSNP
rs1193587810 20 dbSNP
Putative Targets

Gene Information
Gene Symbol PDCD4   
Synonyms H731
Description programmed cell death 4
Transcript NM_014456   
Other Transcripts NM_145341   
Expression
Putative miRNA Targets on PDCD4
3'UTR of PDCD4
(miRNA target sites are highlighted)		 
>PDCD4|NM_014456|3'UTR
   1 ATATAAGAACTCTTGCAGTCTTAGATGTTATAAAAATATATATCTGAATTGTAAGAGTTGTTAGCACAAGTTTTTTTTTT
  81 TTTTTTTTTTAAGCACTTGTTTTGGGTACAAGGCATTTCTGACATTTTATAAACCTACATTTAAGGGGAATTTTTAAAGG
 161 AAATGTTTTTTCTTTTTTTTTTGTTTTTCGAGGGGGCAAGGAGGGACAGAAAAGTAACCTCTTCTTAAGTGGAATATTCT
 241 AATAAGCTACCTTTTGTAAGTGCCATGTTTATTATCTAATCATTCCAAGTTTTGCATTGATGTCTGACTGCCACTCCTTT
 321 CTTTCAAGGACAGTGTTTTTTGTAGTAAAATCACTGGTTTATACAAAGCTTTATTTAGGGGGTAAAGTTAAGCTGCTAAA
 401 ACCCCATGTTGGCTGCTGCTGTTGAGATACTGTGCTTTGGGAGTAAAAAAAGAAAGTTATTTCTTTGTCTTAAAGAATTT
 481 TTAAAAAATTAGTCATGAGACTTATTCATCTTTCCAGGGAACATACTGATTGGTCTTAAAAGACTAGACAGTTAAGTAAA
 561 AGGTGGCTGGAACATCTATTTTTCTACAAAACTGGAAAAATGAACCTGGTTCTAGAAGAATGTACACCAAAATAAAACAT
 641 GTGAAGCAGTATTGATTCTTTATTGGGAGTACATTTTTTTAGGTCTCTTAAACTTTAATTTCACACAGTAAATTTTGAAT
 721 CTCATAAGGAAGCATATTTGAACCTAGTCAATTTAATCTTAGTGTTCCCTTGAAAACTTTTTTTCCCTACAAAATTTTAA
 801 GTGAAAAATACAATAGTAAATTAAGATTACACTGGGGAAAAAAATGCAGGTATCACTTTACTCCATTGTTATCTGACCTA
 881 GAGCTTAATTAAGTTTTAGAAATATGTAATACCTTCCATCATTCCATCATCCTTAAATTCTGTTACCAAATAATGGCTAA
 961 TGTTACAAAAAGTTATACTCCAGAGACCCAAAGCTTGACATTTACCTAATGTATGAGAAAATATTACCAATTAACAATAA
1041 AGAATGATCATATTTTTAACCTCTTTTACATAGCCTAATAACTCAGCAAGGCCTCAACGTCTGTGCTAATTTAAACTGCC
1121 AAATATTGACTGCAGCAAACAAGAATTATATTCAGAATTTATGAGGGTACTGTTAGGAGTATACTGCTTACAGGTTTAGA
1201 TATAGTCTGTTAGAATTAAAACCAAGTTTAGTGTTCATATTTACCTCATGGGCTTTATCAAGCCCATATTACCTCAGCTT
1281 ATATATAGTTACCATTTTTAGGTTTTTAATTGTTTGACACTTGGATGATAAATGCAGTCATTTTATTCTCAAGTGCTTAA
1361 AATTAATGTAATTAAAAGCTTAGCTGACTACAGAATAGGTGAGGGTTTCTTAAAAATGAGATTTAAGGGCTGGGCACGGT
1441 GGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGAGGTTGGGAGTTCATGACCAGCTTGA
1521 CCAACATGAAGAAACCCTGTCTCTATTAAAAATACAAAAGTAGCCAGGCATGGTGGCGCATGCGTGTAATCCCAGCTACT
1601 TGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGTCGAGATGGTGCCATTGCTCTCGTT
1681 TGGGCAACAAGAGTGAAACTCTTGTCTCAAAAAAAAAAAAAAATGAGGTTTAAGACAGTTTTGTCATTACTGGTGGGATC
1761 TGGTCACACAAGATAGCATTAAACGTGACATGGCACATAAAATTGGTTAAAAAATTTTGTTTTTTAATTACGTAATGTAA
1841 AAGCCCAACAAACACTTTATGCAAGATTGGAATGTATCTTCAAATTCAGATTTAATAAACATGTAAAGATCCTCTGTAAA
1921 AAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' auaAC-GUAGAUAGGUUUGGAa 5'
             || |||:| | :|||||| 
Target 5' ttcTGACATTT-TATAAACCTa 3'
 117 - 137 141.00 -10.40
2 
miRNA  3' auaACGUAGAUAGGUUUGGAa 5'
             || :|:||| |||| || 
Target 5' cacTG-GTTTATACAAAGCTt 3'
 352 - 371 129.00 -7.30
3 
miRNA  3' auaaCGUAGAUAGGUUUGGAa 5'
              |||  |||:::||||| 
Target 5' ggaaGCA--TATTTGAACCTa 3'
 728 - 746 129.00 -9.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30513930 41 COSMIC
COSN20077120 61 COSMIC
COSN31586225 62 COSMIC
COSN20107546 90 COSMIC
COSN20077167 91 COSMIC
COSN1112386 124 COSMIC
COSN31586717 163 COSMIC
COSN29083098 183 COSMIC
COSN6056641 348 COSMIC
COSN31589683 369 COSMIC
COSN1112388 373 COSMIC
COSN31577787 380 COSMIC
COSN31569900 453 COSMIC
COSN31534635 476 COSMIC
COSN8149300 579 COSMIC
COSN27555657 1066 COSMIC
COSN6056642 1123 COSMIC
COSN29854732 1331 COSMIC
COSN1471208 1485 COSMIC
COSN20788217 1516 COSMIC
COSN8149301 1520 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs780773533 1 dbSNP
rs192041921 4 dbSNP
rs372012361 5 dbSNP
rs1274530692 8 dbSNP
rs780271274 11 dbSNP
rs1461423681 13 dbSNP
rs749729920 14 dbSNP
rs1252920446 16 dbSNP
rs201739274 17 dbSNP
rs774971106 25 dbSNP
rs748132091 28 dbSNP
rs773643180 28 dbSNP
rs1235425484 29 dbSNP
rs1473481400 31 dbSNP
rs1034503022 32 dbSNP
rs1389478794 33 dbSNP
rs12263197 36 dbSNP
rs1427668941 37 dbSNP
rs376964203 40 dbSNP
rs760994347 41 dbSNP
rs1293533284 50 dbSNP
rs766763981 52 dbSNP
rs1177722312 54 dbSNP
rs1481462408 57 dbSNP
rs945794629 59 dbSNP
rs1254056882 60 dbSNP
rs775140901 61 dbSNP
rs762843302 63 dbSNP
rs763911359 65 dbSNP
rs1296880355 66 dbSNP
rs751537495 68 dbSNP
rs1491521147 70 dbSNP
rs759575771 70 dbSNP
rs761257424 70 dbSNP
rs771292422 70 dbSNP
rs1375667883 71 dbSNP
rs397716645 71 dbSNP
rs5787876 71 dbSNP
rs763160233 71 dbSNP
rs775747835 71 dbSNP
rs776805156 71 dbSNP
rs977086596 71 dbSNP
rs1175129960 74 dbSNP
rs767018039 75 dbSNP
rs750018222 76 dbSNP
rs1344721798 79 dbSNP
rs779798593 81 dbSNP
rs1014210812 87 dbSNP
rs1186940826 91 dbSNP
rs1276051599 91 dbSNP
rs1489992836 91 dbSNP
rs757243971 91 dbSNP
rs1222273709 92 dbSNP
rs1269984987 97 dbSNP
rs1002808943 100 dbSNP
rs749594671 103 dbSNP
rs1192500325 105 dbSNP
rs755392885 106 dbSNP
rs1427468584 107 dbSNP
rs779252577 110 dbSNP
rs1170528262 112 dbSNP
rs556498033 114 dbSNP
rs577882072 115 dbSNP
rs1311283326 130 dbSNP
rs72819730 134 dbSNP
rs1032781331 139 dbSNP
rs1314276292 146 dbSNP
rs1397780523 148 dbSNP
rs1383835412 152 dbSNP
rs554044351 153 dbSNP
rs373862908 158 dbSNP
rs749268636 160 dbSNP
rs1366639391 161 dbSNP
rs1164132811 163 dbSNP
rs1475380272 166 dbSNP
rs1010397344 167 dbSNP
rs1190280165 169 dbSNP
rs1205781530 173 dbSNP
rs1261363981 173 dbSNP
rs138010548 173 dbSNP
rs1486930275 173 dbSNP
rs550230568 173 dbSNP
rs1213640065 180 dbSNP
rs1052550 182 dbSNP
rs1421546024 183 dbSNP
rs1225757702 184 dbSNP
rs966695346 184 dbSNP
rs543153032 190 dbSNP
rs976398998 191 dbSNP
rs1418147360 201 dbSNP
rs1387967989 207 dbSNP
rs12248739 215 dbSNP
rs1167597601 219 dbSNP
rs548643783 219 dbSNP
rs1396652128 220 dbSNP
rs1168248170 240 dbSNP
rs953420949 242 dbSNP
rs1461752056 244 dbSNP
rs1194177840 249 dbSNP
rs1299250990 257 dbSNP
rs1251247168 258 dbSNP
rs1399213623 261 dbSNP
rs1469284066 263 dbSNP
rs1394389347 268 dbSNP
rs146211346 270 dbSNP
rs1339142667 276 dbSNP
rs1251468960 285 dbSNP
rs529863924 287 dbSNP
rs1229185213 293 dbSNP
rs921091660 294 dbSNP
rs768075579 298 dbSNP
rs61469604 303 dbSNP
rs940800810 309 dbSNP
rs1306720036 310 dbSNP
rs756545115 311 dbSNP
rs1409090372 323 dbSNP
rs1396971995 332 dbSNP
rs1168667096 333 dbSNP
rs1463689523 335 dbSNP
rs368483051 336 dbSNP
rs746143494 364 dbSNP
rs1454815676 365 dbSNP
rs1255365411 369 dbSNP
rs1036344767 374 dbSNP
rs1209586899 379 dbSNP
rs1437561198 380 dbSNP
rs1257563402 382 dbSNP
rs1345268277 386 dbSNP
rs1476020013 387 dbSNP
rs1191038232 388 dbSNP
rs1279237536 398 dbSNP
rs1394888963 406 dbSNP
rs899189743 408 dbSNP
rs1349430458 409 dbSNP
rs1277645062 419 dbSNP
rs1336314793 420 dbSNP
rs1441424023 420 dbSNP
rs1330610619 425 dbSNP
rs1373862892 431 dbSNP
rs995078972 442 dbSNP
rs1435356761 448 dbSNP
rs1396989471 451 dbSNP
rs1157300179 460 dbSNP
rs72819732 470 dbSNP
rs905502907 476 dbSNP
rs958946663 476 dbSNP
rs11548764 485 dbSNP
rs1184412616 489 dbSNP
rs1171507735 501 dbSNP
rs1375338553 502 dbSNP
rs1256289038 504 dbSNP
rs1433368499 506 dbSNP
rs796971952 518 dbSNP
rs1376130997 519 dbSNP
rs1281481400 520 dbSNP
rs1054152305 524 dbSNP
rs1351290183 531 dbSNP
rs1416634506 540 dbSNP
rs1231152880 548 dbSNP
rs1354595918 550 dbSNP
rs1312449120 557 dbSNP
rs1361159956 560 dbSNP
rs1415660391 560 dbSNP
rs1316288062 569 dbSNP
rs1400255863 574 dbSNP
rs892875475 579 dbSNP
rs1162010579 587 dbSNP
rs1010030514 588 dbSNP
rs1361479457 599 dbSNP
rs1214962786 606 dbSNP
rs1297423318 610 dbSNP
rs1020458751 613 dbSNP
rs1240057210 614 dbSNP
rs1214449027 619 dbSNP
rs1447082126 619 dbSNP
rs1286187826 621 dbSNP
rs1211765099 626 dbSNP
rs1467628372 629 dbSNP
rs1333829858 635 dbSNP
rs759553259 639 dbSNP
rs1233463322 641 dbSNP
rs1381601649 646 dbSNP
rs1280489142 647 dbSNP
rs998150940 650 dbSNP
rs1268710457 659 dbSNP
rs1430030649 662 dbSNP
rs1486371655 672 dbSNP
rs1029257908 674 dbSNP
rs1323085965 677 dbSNP
rs1460370318 681 dbSNP
rs1394452365 686 dbSNP
rs953785133 691 dbSNP
rs1407499706 711 dbSNP
rs1416863901 713 dbSNP
rs984736615 716 dbSNP
rs1024492157 718 dbSNP
rs1016256413 725 dbSNP
rs761358804 727 dbSNP
rs967132003 729 dbSNP
rs532537004 734 dbSNP
rs139237079 738 dbSNP
rs972129810 745 dbSNP
rs1173577363 746 dbSNP
rs565963166 750 dbSNP
rs1214233230 758 dbSNP
rs957299247 762 dbSNP
rs866368294 765 dbSNP
rs1299886324 770 dbSNP
rs975301420 775 dbSNP
rs1438870762 778 dbSNP
rs949933576 778 dbSNP
rs1436694386 782 dbSNP
rs1353143165 786 dbSNP
rs1169261968 787 dbSNP
rs1156949087 790 dbSNP
rs921142646 791 dbSNP
rs1391686042 793 dbSNP
rs1171185490 804 dbSNP
rs1453342679 810 dbSNP
rs933920544 814 dbSNP
rs1253476559 815 dbSNP
rs1192866878 825 dbSNP
rs981737163 826 dbSNP
rs1431710867 829 dbSNP
rs1205013967 834 dbSNP
rs1050859596 839 dbSNP
rs56875008 858 dbSNP
rs1232087130 860 dbSNP
rs940770586 862 dbSNP
rs1347260445 865 dbSNP
rs1439811981 872 dbSNP
rs1304743483 877 dbSNP
rs1304112024 878 dbSNP
rs1389067216 879 dbSNP
rs1054121612 885 dbSNP
rs1297941842 888 dbSNP
rs376183497 890 dbSNP
rs72377323 890 dbSNP
rs747522218 890 dbSNP
rs549069926 894 dbSNP
rs1036886771 901 dbSNP
rs1237391718 919 dbSNP
rs1310703143 926 dbSNP
rs899161298 927 dbSNP
rs1433500110 932 dbSNP
rs1395185722 950 dbSNP
rs373508013 960 dbSNP
rs1407235544 961 dbSNP
rs1417208347 961 dbSNP
rs994799070 962 dbSNP
rs531826405 968 dbSNP
rs1282905790 970 dbSNP
rs1317214605 977 dbSNP
rs796147119 981 dbSNP
rs1244565042 986 dbSNP
rs1485361887 990 dbSNP
rs1341930842 995 dbSNP
rs1256632329 1007 dbSNP
rs1041503944 1008 dbSNP
rs901977228 1011 dbSNP
rs571420900 1013 dbSNP
rs894701212 1014 dbSNP
rs1413826408 1019 dbSNP
rs537866454 1029 dbSNP
rs1269091786 1039 dbSNP
rs1304061122 1039 dbSNP
rs1344463009 1043 dbSNP
rs1175594613 1050 dbSNP
rs1014533843 1059 dbSNP
rs1415433303 1061 dbSNP
rs1473421423 1061 dbSNP
rs1407340708 1067 dbSNP
rs796343911 1072 dbSNP
rs1257198173 1073 dbSNP
rs1202245029 1076 dbSNP
rs1484937899 1078 dbSNP
rs1315592630 1080 dbSNP
rs367711802 1080 dbSNP
rs568306693 1080 dbSNP
rs1331622994 1081 dbSNP
rs962020555 1097 dbSNP
rs745440231 1098 dbSNP
rs972098737 1099 dbSNP
rs1355688308 1100 dbSNP
rs1314431931 1105 dbSNP
rs1161567474 1106 dbSNP
rs967980002 1109 dbSNP
rs1379965358 1111 dbSNP
rs2146544 1119 dbSNP
rs143977617 1132 dbSNP
rs1392260035 1141 dbSNP
rs1458719530 1141 dbSNP
rs1033217144 1146 dbSNP
rs1461828075 1153 dbSNP
rs1369205435 1158 dbSNP
rs1326311133 1161 dbSNP
rs957148553 1166 dbSNP
rs1373154558 1179 dbSNP
rs971248810 1180 dbSNP
rs1261170021 1189 dbSNP
rs1189344889 1190 dbSNP
rs975018707 1191 dbSNP
rs981281339 1193 dbSNP
rs1278505215 1197 dbSNP
rs1213381496 1201 dbSNP
rs1373445108 1202 dbSNP
rs115021775 1204 dbSNP
rs958605891 1205 dbSNP
rs990076859 1207 dbSNP
rs914204576 1210 dbSNP
rs1333642953 1227 dbSNP
rs1436718766 1233 dbSNP
rs775616314 1241 dbSNP
rs1325145977 1244 dbSNP
rs1441291023 1250 dbSNP
rs116669104 1252 dbSNP
rs1165182596 1258 dbSNP
rs1460632964 1259 dbSNP
rs572244618 1264 dbSNP
rs1451409709 1269 dbSNP
rs923025458 1277 dbSNP
rs1193579254 1279 dbSNP
rs532881191 1285 dbSNP
rs1194487317 1286 dbSNP
rs1050607723 1289 dbSNP
rs117501349 1292 dbSNP
rs973935747 1293 dbSNP
rs1345137187 1294 dbSNP
rs576331563 1300 dbSNP
rs1470554249 1303 dbSNP
rs1233923377 1310 dbSNP
rs1302527597 1310 dbSNP
rs920641886 1313 dbSNP
rs1326585305 1316 dbSNP
rs1416027735 1319 dbSNP
rs1390666987 1320 dbSNP
rs897802703 1326 dbSNP
rs1474987377 1330 dbSNP
rs571704165 1345 dbSNP
rs1165468211 1348 dbSNP
rs930727918 1351 dbSNP
rs1396393823 1355 dbSNP
rs535870892 1357 dbSNP
rs1055780881 1358 dbSNP
rs894504715 1363 dbSNP
rs950268884 1364 dbSNP
rs993447482 1365 dbSNP
rs1379939259 1366 dbSNP
rs543427963 1367 dbSNP
rs1328106739 1369 dbSNP
rs1437682329 1369 dbSNP
rs1206910800 1371 dbSNP
rs768527963 1372 dbSNP
rs903350635 1374 dbSNP
rs760414646 1376 dbSNP
rs1278939229 1377 dbSNP
rs184164741 1385 dbSNP
rs763246128 1393 dbSNP
rs958532831 1397 dbSNP
rs532647939 1403 dbSNP
rs1290877178 1404 dbSNP
rs1289189660 1405 dbSNP
rs892861715 1410 dbSNP
rs914476331 1417 dbSNP
rs1233514747 1419 dbSNP
rs996573900 1423 dbSNP
rs867314467 1429 dbSNP
rs541373922 1434 dbSNP
rs146414879 1438 dbSNP
rs188713884 1439 dbSNP
rs922962287 1448 dbSNP
rs1184824515 1452 dbSNP
rs1473991969 1453 dbSNP
rs1475087791 1457 dbSNP
rs1256381142 1464 dbSNP
rs1210122140 1465 dbSNP
rs1443703773 1476 dbSNP
rs1258448635 1477 dbSNP
rs1015886528 1484 dbSNP
rs1272955212 1485 dbSNP
rs961325608 1486 dbSNP
rs974284621 1489 dbSNP
rs774549387 1492 dbSNP
rs910691078 1499 dbSNP
rs919788416 1503 dbSNP
rs930696809 1510 dbSNP
rs991600931 1517 dbSNP
rs1316811264 1522 dbSNP
rs548773635 1522 dbSNP
rs915907321 1527 dbSNP
rs950071375 1532 dbSNP
rs1037856868 1536 dbSNP
rs1188942375 1537 dbSNP
rs1412609944 1538 dbSNP
rs1182140294 1539 dbSNP
rs1420208111 1539 dbSNP
rs1473478135 1544 dbSNP
rs1474322629 1545 dbSNP
rs898068979 1554 dbSNP
rs1045735530 1556 dbSNP
rs1465247978 1561 dbSNP
rs993744051 1569 dbSNP
rs903401797 1575 dbSNP
rs377721423 1578 dbSNP
rs1289403011 1582 dbSNP
rs906527793 1585 dbSNP
rs1310614704 1588 dbSNP
rs934945278 1591 dbSNP
rs1414802660 1592 dbSNP
rs1366467780 1599 dbSNP
rs1034191190 1600 dbSNP
rs561051882 1606 dbSNP
rs958134628 1607 dbSNP
rs1165971583 1613 dbSNP
rs55858908 1618 dbSNP
rs1324275923 1620 dbSNP
rs192265483 1623 dbSNP
rs1021504349 1627 dbSNP
rs1191722221 1629 dbSNP
rs149734425 1632 dbSNP
rs1269951480 1647 dbSNP
rs1247026005 1648 dbSNP
rs1340769730 1649 dbSNP
rs1453481319 1654 dbSNP
rs182879722 1656 dbSNP
rs1227752499 1658 dbSNP
rs1278743357 1659 dbSNP
rs1028068006 1660 dbSNP
rs11548763 1664 dbSNP
rs145626064 1678 dbSNP
rs1232697157 1679 dbSNP
rs1211639143 1685 dbSNP
rs1258557671 1686 dbSNP
rs1445472299 1687 dbSNP
rs1192252744 1689 dbSNP
rs1367550079 1689 dbSNP
rs1294429727 1691 dbSNP
rs187023714 1694 dbSNP
rs1476382871 1695 dbSNP
rs1171696543 1701 dbSNP
rs985875614 1702 dbSNP
rs1307089275 1703 dbSNP
rs1394327171 1705 dbSNP
rs1429801064 1708 dbSNP
rs1434828084 1708 dbSNP
rs1491333548 1708 dbSNP
rs754057095 1708 dbSNP
rs1204760448 1709 dbSNP
rs1249869792 1709 dbSNP
rs1420323869 1709 dbSNP
rs1483525287 1709 dbSNP
rs200583503 1709 dbSNP
rs201736448 1709 dbSNP
rs537232273 1709 dbSNP
rs1015272907 1711 dbSNP
rs1382380498 1712 dbSNP
rs961565790 1723 dbSNP
rs1318149006 1724 dbSNP
rs1475634434 1725 dbSNP
rs941813166 1726 dbSNP
rs973533031 1729 dbSNP
rs1301926492 1730 dbSNP
rs1410013506 1737 dbSNP
rs919464628 1742 dbSNP
rs1396238820 1750 dbSNP
rs974041950 1752 dbSNP
rs565692123 1759 dbSNP
rs929534218 1770 dbSNP
rs1047092035 1771 dbSNP
rs1348891381 1773 dbSNP
rs558844759 1780 dbSNP
rs554731075 1785 dbSNP
rs1182664658 1786 dbSNP
rs577554924 1794 dbSNP
rs1254253150 1797 dbSNP
rs1180188349 1804 dbSNP
rs1191469549 1807 dbSNP
rs1252318986 1815 dbSNP
rs1454637875 1816 dbSNP
rs1212911329 1818 dbSNP
rs991569865 1822 dbSNP
rs915959835 1826 dbSNP
rs1267842582 1828 dbSNP
rs754084731 1832 dbSNP
rs576468849 1833 dbSNP
rs1394930265 1835 dbSNP
rs757693138 1837 dbSNP
rs1021430769 1838 dbSNP
rs1451482480 1839 dbSNP
rs569691826 1841 dbSNP
rs998754097 1845 dbSNP
rs1386634026 1852 dbSNP
rs537134116 1859 dbSNP
rs558527459 1861 dbSNP
rs1163010892 1875 dbSNP
rs1423286685 1879 dbSNP
rs764810501 1879 dbSNP
rs34559036 1881 dbSNP
rs986187058 1892 dbSNP
rs1463887438 1901 dbSNP
rs1247952586 1912 dbSNP
rs1209742766 1915 dbSNP
rs1263288517 1917 dbSNP
rs1331728099 1917 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' auaacGUAGAUAGGUUUGGAa 5'
               |||:| | :|||||| 
Target 5' ----aCAUUU-UAUAAACCUa 3'
 		1 - 16
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000280154.7 | 3UTR | ACAUUUUAUAAACCUACAUUUAAGGGGAAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
81 hsa-miR-4464 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT056004 ARL5B ADP ribosylation factor like GTPase 5B 2 2
MIRT061568 BTG2 BTG anti-proliferation factor 2 2 2
MIRT078651 ICT1 mitochondrial ribosomal protein L58 2 2
MIRT087551 YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta 2 4
MIRT088139 SEPT2 septin 2 2 4
MIRT095089 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT099065 FOXC1 forkhead box C1 2 4
MIRT150194 MIDN midnolin 2 2
MIRT178173 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 4
MIRT178942 C11ORF57 chromosome 11 open reading frame 57 2 2
MIRT188776 SESN2 sestrin 2 2 2
MIRT267026 EFHD2 EF-hand domain family member D2 2 2
MIRT307213 ACVR2B activin A receptor type 2B 2 2
MIRT324750 ACER2 alkaline ceramidase 2 2 2
MIRT442732 TEAD1 TEA domain transcription factor 1 2 2
MIRT444087 C12orf73 chromosome 12 open reading frame 73 2 2
MIRT445527 KLF9 Kruppel like factor 9 2 2
MIRT449604 INIP INTS3 and NABP interacting protein 2 2
MIRT451129 ZNF99 zinc finger protein 99 2 2
MIRT452271 RPL30 ribosomal protein L30 2 2
MIRT452486 DDX4 DEAD-box helicase 4 2 2
MIRT454868 DNAJC15 DnaJ heat shock protein family (Hsp40) member C15 2 6
MIRT455773 TSPAN6 tetraspanin 6 2 4
MIRT463844 WRN Werner syndrome RecQ like helicase 2 2
MIRT465036 TTC39C tetratricopeptide repeat domain 39C 2 2
MIRT465176 TRPV2 transient receptor potential cation channel subfamily V member 2 2 4
MIRT465294 TRIB3 tribbles pseudokinase 3 2 4
MIRT467931 SLC16A7 solute carrier family 16 member 7 2 2
MIRT471906 NUAK2 NUAK family kinase 2 2 2
MIRT472724 MTUS1 microtubule associated scaffold protein 1 2 6
MIRT479785 CCND1 cyclin D1 2 2
MIRT482446 ADM adrenomedullin 2 10
MIRT485365 MYLIP myosin regulatory light chain interacting protein 2 12
MIRT498399 KIF6 kinesin family member 6 2 2
MIRT503202 ACTB actin beta 2 6
MIRT503819 TMEM242 transmembrane protein 242 2 2
MIRT504706 ZNF117 zinc finger protein 117 2 2
MIRT507802 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT509968 KANSL1L KAT8 regulatory NSL complex subunit 1 like 2 4
MIRT517306 ELF4 E74 like ETS transcription factor 4 2 6
MIRT523900 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2 6
MIRT532018 NOX5 NADPH oxidase 5 2 2
MIRT535334 PHACTR2 phosphatase and actin regulator 2 2 2
MIRT536944 HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2 4
MIRT539322 AHSA2 activator of HSP90 ATPase homolog 2 2 2
MIRT540189 GSTM4 glutathione S-transferase mu 4 2 2
MIRT545015 ZNF439 zinc finger protein 439 2 2
MIRT545265 TRIM36 tripartite motif containing 36 2 4
MIRT547230 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 4
MIRT548425 ELOVL5 ELOVL fatty acid elongase 5 2 2
MIRT549910 ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 2 2
MIRT550185 TMEM106C transmembrane protein 106C 2 2
MIRT550775 ENOX2 ecto-NOX disulfide-thiol exchanger 2 2 4
MIRT552401 ZNF487P zinc finger protein 487 1 1
MIRT554782 RHEBP1 RHEB pseudogene 1 2 4
MIRT557311 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT558635 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT563168 RPS14 ribosomal protein S14 2 2
MIRT564886 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 2 2
MIRT565778 SEPHS1 selenophosphate synthetase 1 2 2
MIRT566480 PDCD4 programmed cell death 4 2 2
MIRT567206 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT568931 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT570698 FBXO41 F-box protein 41 2 2
MIRT573474 MTRNR2L9 MT-RNR2-like 9 2 2
MIRT576170 Hmox1 heme oxygenase 1 2 2
MIRT607555 GLI2 GLI family zinc finger 2 2 2
MIRT608203 ERBB2 erb-b2 receptor tyrosine kinase 2 2 2
MIRT609779 VWC2L von Willebrand factor C domain containing protein 2 like 2 4
MIRT616312 CELF2 CUGBP Elav-like family member 2 2 2
MIRT617190 CDH13 cadherin 13 2 2
MIRT626842 RPLP1 ribosomal protein lateral stalk subunit P1 2 2
MIRT636438 MARCH1 membrane associated ring-CH-type finger 1 2 2
MIRT639101 GLIPR1L2 GLI pathogenesis related 1 like 2 2 2
MIRT691018 CRTC3 CREB regulated transcription coactivator 3 2 2
MIRT700008 RPS21 ribosomal protein S21 2 2
MIRT701144 PANK1 pantothenate kinase 1 2 2
MIRT712691 NUDT7 nudix hydrolase 7 2 2
MIRT715505 MAZ MYC associated zinc finger protein 2 2
MIRT722509 PTPRC protein tyrosine phosphatase, receptor type C 2 2
MIRT724982 TNS1 tensin 1 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miR-4464 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4464 Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)

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