miRTarBase - #MIRT570802


—
pre-miRNA Information
pre-miRNA hsa-mir-4720   
Genomic Coordinates chr16: 81385018 - 81385093
Description Homo sapiens miR-4720 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4720-5p
Sequence 4| CCUGGCAUAUUUGGUAUAACUU |25
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs750386566 4 dbSNP
rs532921899 5 dbSNP
rs1025678089 6 dbSNP
rs1435476609 11 dbSNP
rs1426449829 13 dbSNP
rs1349517705 17 dbSNP
rs1448030025 20 dbSNP
Putative Targets

Gene Information
Gene Symbol CKAP2L   
Synonyms -
Description cytoskeleton associated protein 2 like
Transcript NM_152515   
Expression
Putative miRNA Targets on CKAP2L
3'UTR of CKAP2L
(miRNA target sites are highlighted)		 
>CKAP2L|NM_152515|3'UTR
   1 TTTCTTGATGCTTTTTTTAAAAAAGGTGTTTCAGAACCAACATAAGACAAGAAATATTCTTGTCCAAGTGACCTGGAAAA
  81 AAAGAGAGGCATCATGGATGCAGATTATGGACGCTCAGGACTTAAGTAATTCACTGGGCTTACTCTCAAATTTTCTCTCC
 161 CCATGGGAAAATCTTTGCTTTATGTGTTTAAGACCAGTTTGCCAGTTTTACAGTATACATAAATTTCAAACTTTTGAATA
 241 TTTACCCTACAACTATGATAAATATTTATACTTTATTGATCTACTTTAATCCCAACATAGTTTTTTATATCAGAAGGTTG
 321 GTCCCACAATATAATGGGACTTTTCTTTCTGCATCCACCTTAGCAGAGGGCAAGTTCTTTCATCGTGGAAGATCTGAACT
 401 TTGACGCTAGCTTGACAGGCTGAATGGACCTTGACAGATGGCCAAGTCAAAACCCCTCATTTTACAGATGAGTTTATGCT
 481 AGCTGTGCCTTTGCTCAGAGATCATAAATTTATGTGTGATCTTTGACTTTCATCACAGTATCCTTGTAAATGAGAGAGAA
 561 TTCTTGTTTTTTCTATGCCAGGTCTCCTCAGATGAAACACAATCCTGAATTGGCATGGTCGTCTAGCTTTTATATTCAAA
 641 CCTAGTTTTGCATTTGTTACTCAGAAACACTTCAAGTAACAAAAGGGGGGCAGGGGAGAGGGGTGGGGAGTGGACACTTG
 721 CTTCTTCAGTTCTTTGCTCAGCTAGGGTATAGCTGGCCTGAGAAGGCAGTGCAAGCCCCAGAGACTGTTGTAGGTTGCTT
 801 TTTCTTCCTCCTGGGCAACTATTTGTGGAAAGGTTTTACCTTAGTCATTATGTAAATATAATTGTGTAGAAAAACCTAGT
 881 CAACACATTTTAAATTTTAGCTTTCTTAATATTTAAGTATTATCTTAAAACAACATTAAATTTCTATTAGTTCCTGCTTG
 961 TTTATCTTATTTATTATAGAAAACCATGATAATGGCTTTGCATAGAGAATTAGGAGTTTGTCTAAGGATATACCAGTTGG
1041 CTGTCCTAAGAAACAAGGAGCATTCATTACCAAGGAGAATGGACTTTGATCAAAGGTCTATCAGCCTCATCCAGGAACTA
1121 GATTTTTTTAAGGGAAGCAGATCTATTTCTGAAAGTCAGATTTATAATAAAGCTCAAAAAACTGAGCTATAAACCTGTAA
1201 TACCAGCAGACTTTCAATAAGAGACTCTTACAACTCAATTGTGGAAAAACTAATAATTAAAAATGGGCAAAGGACCTGAG
1281 CAGACATTTCTCCAAAGAAGACATAAGAAATGGCCAGTAGGTATAGATATGAAAAGGTGTTCAGCATCATTAATCATAAG
1361 AATAATGTAAATTAAAACCACTGTGAGCTATCACCTCACATCTATAAGAATGGCTATTAACAAGACATGAGATAAATGTT
1441 GATGAGATTGTGGAGAAAAGAGAACCCTAGTACACTGTTTGTGGGCGTGTAGACTGGGGCAGCCGTTATGGAAAACGGTA
1521 TGGAGGCTCCTAAAGAAATTAAAAATAGAACTGTTATCTGACCCTCTTCTGAGTAAGTATGTACCCAAAGAAGATGAAAT
1601 CACCAGCTGGGCGCAGTGACTCACACCTGTAATCCCAGCACTTTGGAGTGGGTGAATCACCTGAGGTCAGGAGTTCAAGA
1681 CCAGCTTGACCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAGTAGGCGGGCATGGTGACGGGCACCTGTAAT
1761 CCCAGCTACTTGGGAGGCTGAGGCAGAAGAATCACTTGAACTCGGGAGGTGGAGGTTGCAGTGAGCCAAAATTGCGTCAC
1841 TGCACTCCAGCCTGGGTTACAGAGCAAGACTCCATCTCAAAAAAAAAAAAGATGAAATCATCACCTCATAAAGATATCTG
1921 CACTCACATGTTTGTGGCAGTGTTATTCTCAATAGCCAAGATGTGGAAACAACCTAAATGCCCATCAATGGACAAATAAA
2001 GAAAATACGGCATATGCATGCCGTGGAATAGTATTCATCCTTGGAAAAGAGGGAGTTCTTGCCATTTGCCACAACATAGA
2081 TGGACCTGGAGAACATTATGCTAAGTGAAATAAGCCAGACCCAAGGAAAAATACTGCATGATCTCACATATGGAATATTT
2161 AATTTTTTAAGAAAGAGCTCAAGTACACAGAGAAAGTGCTTACCACAGATTGGGGAAGAGGAAATGGGGAGATGCAGGCC
2241 AAGGATACAAAATAGCAGATAAAATGAACAAGTCTAGAGATAGGGCTAAAGTTAATACAATTGTATTAGGGATTTTTGTT
2321 AAATAAGTAGATTTTAGCTGCTATTATCACAAAAAAACTGAGATGATAATGTTAATCTGCTTCACTATAGCAGCCATTTT
2401 ATTATCTATATGTATCCCATAACATCATGTTGTAAATCTTAAATATACCTAATAAAATAAAATTGTCACCAAAAAAAAAA
2481 AAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuCAAUAUGGUUUAUACGGUCc 5'
            ||| | :|   |||||||| 
Target 5' ttGTTTTTTC---TATGCCAGg 3'
 564 - 582 153.00 -14.00
2 
miRNA  3' uucAAUAUGG-----UUUAUACGGUCc 5'
             ||||:|:     ||||| ||||| 
Target 5' acaTTATGCTAAGTGAAATAAGCCAGa 3'
 2093 - 2119 139.00 -13.60
3 
miRNA  3' uucAAUAUG---GUUU--AUACGGUCc 5'
             || |||   ::|:  |||||:|| 
Target 5' tcaTTTTACAGATGAGTTTATGCTAGc 3'
 457 - 483 137.00 -7.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30167137 8 COSMIC
COSN24402160 18 COSMIC
COSN5269991 56 COSMIC
COSN505827 76 COSMIC
COSN30511763 88 COSMIC
COSN28842577 89 COSMIC
COSN1221835 112 COSMIC
COSN17182242 162 COSMIC
COSN5125445 729 COSMIC
COSN28218133 1301 COSMIC
COSN16316091 1439 COSMIC
COSN20575836 1462 COSMIC
COSN27694410 1476 COSMIC
COSN32062291 1878 COSMIC
COSN28202163 2079 COSMIC
COSN24475414 2200 COSMIC
COSN197455 2359 COSMIC
rs148811971 1804 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs779434277 4 dbSNP
rs757582894 10 dbSNP
rs1004910161 12 dbSNP
rs1438539090 14 dbSNP
rs754274525 18 dbSNP
rs1168496909 19 dbSNP
rs765776128 19 dbSNP
rs1393070922 22 dbSNP
rs886427173 24 dbSNP
rs1365844979 25 dbSNP
rs764407057 25 dbSNP
rs752907268 26 dbSNP
rs757723098 27 dbSNP
rs767600827 31 dbSNP
rs753370153 32 dbSNP
rs1341612166 41 dbSNP
rs139384306 42 dbSNP
rs774189329 44 dbSNP
rs770855085 45 dbSNP
rs762778094 48 dbSNP
rs200736867 52 dbSNP
rs144642601 56 dbSNP
rs759942971 66 dbSNP
rs1057063796 67 dbSNP
rs76587127 78 dbSNP
rs771415221 79 dbSNP
rs1360458163 84 dbSNP
rs577431814 86 dbSNP
rs533897338 87 dbSNP
rs1489345443 89 dbSNP
rs571447059 94 dbSNP
rs1241488157 100 dbSNP
rs1474282110 102 dbSNP
rs942087257 107 dbSNP
rs1183391419 112 dbSNP
rs1385397994 114 dbSNP
rs910765152 121 dbSNP
rs773890881 124 dbSNP
rs1161343985 133 dbSNP
rs1361867803 135 dbSNP
rs986283856 143 dbSNP
rs1319509461 149 dbSNP
rs954953020 150 dbSNP
rs1326381001 159 dbSNP
rs1323433459 163 dbSNP
rs1428994769 176 dbSNP
rs1317620149 185 dbSNP
rs554426429 193 dbSNP
rs976825253 195 dbSNP
rs746135131 208 dbSNP
rs551638582 212 dbSNP
rs6756392 214 dbSNP
rs1010694503 216 dbSNP
rs1283415493 228 dbSNP
rs1445212553 230 dbSNP
rs1212234409 234 dbSNP
rs1345805061 241 dbSNP
rs1305876448 245 dbSNP
rs781250864 245 dbSNP
rs1181331913 249 dbSNP
rs893538560 252 dbSNP
rs912183929 255 dbSNP
rs569182320 260 dbSNP
rs1374877583 268 dbSNP
rs1052529 269 dbSNP
rs1399465394 270 dbSNP
rs1339343736 271 dbSNP
rs1469291576 276 dbSNP
rs906477984 279 dbSNP
rs954908543 280 dbSNP
rs1452420626 281 dbSNP
rs1046272023 284 dbSNP
rs993915235 286 dbSNP
rs1178389172 293 dbSNP
rs1334923033 300 dbSNP
rs897862455 301 dbSNP
rs1279028592 302 dbSNP
rs1348703480 307 dbSNP
rs1038105963 310 dbSNP
rs1181370059 317 dbSNP
rs963863091 341 dbSNP
rs1201557057 345 dbSNP
rs1239554495 355 dbSNP
rs530066842 360 dbSNP
rs1177847446 361 dbSNP
rs191863798 377 dbSNP
rs1478755761 378 dbSNP
rs1179171133 380 dbSNP
rs561144935 392 dbSNP
rs1461295546 393 dbSNP
rs779845465 405 dbSNP
rs187022395 406 dbSNP
rs1399165826 407 dbSNP
rs933434163 407 dbSNP
rs1328490898 408 dbSNP
rs1334024327 409 dbSNP
rs923526158 411 dbSNP
rs977736499 414 dbSNP
rs527813739 416 dbSNP
rs968031101 417 dbSNP
rs913590081 430 dbSNP
rs1322747415 433 dbSNP
rs989093538 438 dbSNP
rs1252851448 453 dbSNP
rs1339900419 455 dbSNP
rs1194854246 456 dbSNP
rs1248033598 459 dbSNP
rs757454499 464 dbSNP
rs534366542 468 dbSNP
rs1490687004 476 dbSNP
rs565126260 477 dbSNP
rs1057432402 487 dbSNP
rs1480392434 499 dbSNP
rs1174973557 502 dbSNP
rs1318352050 503 dbSNP
rs545242589 504 dbSNP
rs1001995945 510 dbSNP
rs1451254821 511 dbSNP
rs576564143 532 dbSNP
rs905820140 535 dbSNP
rs1453204556 536 dbSNP
rs1383989412 538 dbSNP
rs1426564301 545 dbSNP
rs1303840437 557 dbSNP
rs1345039542 558 dbSNP
rs1403014612 566 dbSNP
rs1297698916 568 dbSNP
rs775849165 569 dbSNP
rs149559633 573 dbSNP
rs1156581073 581 dbSNP
rs542967543 582 dbSNP
rs1222502083 590 dbSNP
rs1290378151 591 dbSNP
rs1451981459 591 dbSNP
rs769334060 592 dbSNP
rs993469353 600 dbSNP
rs1192936689 602 dbSNP
rs1371482080 602 dbSNP
rs897720582 604 dbSNP
rs1159378733 610 dbSNP
rs573553559 614 dbSNP
rs10209160 615 dbSNP
rs889204919 620 dbSNP
rs1050464946 621 dbSNP
rs1293185750 647 dbSNP
rs1462109156 649 dbSNP
rs1261539419 666 dbSNP
rs1203727646 670 dbSNP
rs1356587355 673 dbSNP
rs1486671870 675 dbSNP
rs181492903 685 dbSNP
rs554704754 685 dbSNP
rs189855678 686 dbSNP
rs184155476 687 dbSNP
rs1316460345 690 dbSNP
rs1246698520 691 dbSNP
rs1325784492 692 dbSNP
rs1446875325 695 dbSNP
rs138177762 697 dbSNP
rs1383681657 699 dbSNP
rs568970679 700 dbSNP
rs1385340056 702 dbSNP
rs878911957 703 dbSNP
rs1161397937 709 dbSNP
rs1364246996 710 dbSNP
rs989125978 712 dbSNP
rs1452964704 713 dbSNP
rs957662264 719 dbSNP
rs1407985456 720 dbSNP
rs974977477 723 dbSNP
rs963590465 725 dbSNP
rs1380141333 727 dbSNP
rs549229413 728 dbSNP
rs1165530544 735 dbSNP
rs980524982 739 dbSNP
rs1238936041 747 dbSNP
rs1266825818 760 dbSNP
rs2676122 766 dbSNP
rs2716671 767 dbSNP
rs950830795 769 dbSNP
rs1242702579 771 dbSNP
rs1191607670 784 dbSNP
rs1482403493 785 dbSNP
rs1179243968 787 dbSNP
rs1430700463 789 dbSNP
rs535409974 789 dbSNP
rs1262787785 792 dbSNP
rs150416463 794 dbSNP
rs375913114 799 dbSNP
rs1002870172 800 dbSNP
rs1489713672 816 dbSNP
rs1357280386 820 dbSNP
rs181016968 821 dbSNP
rs1222542215 823 dbSNP
rs993706148 823 dbSNP
rs962003802 825 dbSNP
rs1338720317 826 dbSNP
rs1011880362 830 dbSNP
rs375252836 832 dbSNP
rs1053323982 834 dbSNP
rs1016147802 836 dbSNP
rs1262907775 840 dbSNP
rs1006232280 841 dbSNP
rs1229466929 843 dbSNP
rs1206851553 844 dbSNP
rs1326806210 847 dbSNP
rs1233696666 848 dbSNP
rs1480319798 850 dbSNP
rs1180120070 858 dbSNP
rs934503393 859 dbSNP
rs112680000 864 dbSNP
rs1198675236 870 dbSNP
rs1404625388 876 dbSNP
rs1170660112 879 dbSNP
rs1353584282 880 dbSNP
rs889154257 887 dbSNP
rs1028995051 889 dbSNP
rs1305089584 895 dbSNP
rs1406079385 900 dbSNP
rs932332877 908 dbSNP
rs1365877190 914 dbSNP
rs997623407 921 dbSNP
rs1216707425 925 dbSNP
rs1273902101 932 dbSNP
rs901910234 933 dbSNP
rs975008578 934 dbSNP
rs942235099 936 dbSNP
rs909387534 946 dbSNP
rs1198563274 949 dbSNP
rs10206303 955 dbSNP
rs950912786 964 dbSNP
rs1186903274 976 dbSNP
rs946184352 976 dbSNP
rs1418271933 977 dbSNP
rs893391345 996 dbSNP
rs1424861593 1004 dbSNP
rs1035762919 1006 dbSNP
rs1199144672 1013 dbSNP
rs551469492 1014 dbSNP
rs981480214 1020 dbSNP
rs1270565380 1023 dbSNP
rs1199069951 1024 dbSNP
rs1054603493 1025 dbSNP
rs1271132291 1028 dbSNP
rs1270190655 1033 dbSNP
rs1197495653 1034 dbSNP
rs1360207892 1049 dbSNP
rs1339974112 1054 dbSNP
rs1221872850 1060 dbSNP
rs1287574265 1062 dbSNP
rs1448669997 1065 dbSNP
rs139210200 1066 dbSNP
rs1463419475 1069 dbSNP
rs752843845 1072 dbSNP
rs765436578 1077 dbSNP
rs980387516 1082 dbSNP
rs55712130 1084 dbSNP
rs1409609653 1085 dbSNP
rs1402939304 1092 dbSNP
rs1319608979 1096 dbSNP
rs1356190074 1098 dbSNP
rs543285323 1100 dbSNP
rs574287396 1101 dbSNP
rs759694522 1104 dbSNP
rs1338891266 1105 dbSNP
rs1031584788 1108 dbSNP
rs999117864 1121 dbSNP
rs917632835 1123 dbSNP
rs1353011562 1130 dbSNP
rs1224253581 1136 dbSNP
rs1285468667 1145 dbSNP
rs1326751838 1160 dbSNP
rs1437378431 1164 dbSNP
rs1205343885 1171 dbSNP
rs1335261676 1171 dbSNP
rs1460593409 1172 dbSNP
rs56152754 1173 dbSNP
rs962149763 1177 dbSNP
rs1050843310 1178 dbSNP
rs1470232841 1187 dbSNP
rs540280633 1189 dbSNP
rs1176221977 1197 dbSNP
rs753185592 1215 dbSNP
rs558395729 1231 dbSNP
rs941031040 1232 dbSNP
rs953257236 1238 dbSNP
rs1172804207 1240 dbSNP
rs1469254123 1255 dbSNP
rs765936070 1256 dbSNP
rs1443046670 1263 dbSNP
rs754186431 1273 dbSNP
rs909496313 1276 dbSNP
rs1326995071 1278 dbSNP
rs115694288 1280 dbSNP
rs929495412 1285 dbSNP
rs1344099664 1286 dbSNP
rs981511201 1303 dbSNP
rs1242483943 1317 dbSNP
rs879187041 1328 dbSNP
rs997896000 1328 dbSNP
rs761166402 1330 dbSNP
rs1263470657 1332 dbSNP
rs901945681 1342 dbSNP
rs79312323 1344 dbSNP
rs1020748655 1345 dbSNP
rs1010413256 1347 dbSNP
rs1202303279 1353 dbSNP
rs1430401311 1356 dbSNP
rs188220001 1371 dbSNP
rs1350226081 1380 dbSNP
rs915920729 1386 dbSNP
rs1398921373 1390 dbSNP
rs748005143 1393 dbSNP
rs990595488 1398 dbSNP
rs1054551023 1400 dbSNP
rs1277898571 1400 dbSNP
rs957376016 1404 dbSNP
rs1032033901 1411 dbSNP
rs112365449 1416 dbSNP
rs1394832477 1424 dbSNP
rs955208903 1424 dbSNP
rs1451011225 1429 dbSNP
rs1029460185 1430 dbSNP
rs1271516976 1435 dbSNP
rs1339663928 1442 dbSNP
rs760859991 1446 dbSNP
rs906114265 1448 dbSNP
rs1044726344 1457 dbSNP
rs1490712208 1460 dbSNP
rs1225335297 1464 dbSNP
rs1268707423 1476 dbSNP
rs949029410 1480 dbSNP
rs899616213 1483 dbSNP
rs1335256003 1484 dbSNP
rs142573375 1486 dbSNP
rs55832935 1487 dbSNP
rs1168249192 1490 dbSNP
rs886766436 1491 dbSNP
rs1159842524 1495 dbSNP
rs1260584341 1499 dbSNP
rs1389941782 1502 dbSNP
rs940448262 1504 dbSNP
rs909069010 1505 dbSNP
rs929537337 1508 dbSNP
rs55960457 1509 dbSNP
rs953287915 1512 dbSNP
rs1028891864 1516 dbSNP
rs1246109178 1517 dbSNP
rs1045843299 1521 dbSNP
rs976112785 1525 dbSNP
rs1488435626 1526 dbSNP
rs55900444 1528 dbSNP
rs1214772255 1539 dbSNP
rs1264271870 1542 dbSNP
rs1020277744 1546 dbSNP
rs1188119605 1547 dbSNP
rs1282447462 1548 dbSNP
rs990236630 1554 dbSNP
rs1164299075 1555 dbSNP
rs1010777821 1557 dbSNP
rs1456318987 1571 dbSNP
rs769437872 1572 dbSNP
rs546492391 1577 dbSNP
rs957614046 1579 dbSNP
rs1318069372 1580 dbSNP
rs183687749 1580 dbSNP
rs1033171746 1581 dbSNP
rs977742459 1582 dbSNP
rs1354508722 1584 dbSNP
rs1243212652 1592 dbSNP
rs1263047024 1594 dbSNP
rs1314399137 1610 dbSNP
rs115382998 1612 dbSNP
rs552119066 1613 dbSNP
rs1303830236 1614 dbSNP
rs1046369101 1641 dbSNP
rs1014499207 1644 dbSNP
rs896177325 1650 dbSNP
rs1430431174 1664 dbSNP
rs1255532726 1667 dbSNP
rs148164701 1668 dbSNP
rs1161152166 1683 dbSNP
rs1412654485 1686 dbSNP
rs940463480 1693 dbSNP
rs1456457613 1695 dbSNP
rs76215821 1698 dbSNP
rs908933308 1707 dbSNP
rs1048943405 1708 dbSNP
rs1452885575 1726 dbSNP
rs531742234 1734 dbSNP
rs1005273867 1735 dbSNP
rs1376293703 1736 dbSNP
rs369562203 1738 dbSNP
rs921854472 1740 dbSNP
rs770611318 1747 dbSNP
rs746866193 1748 dbSNP
rs913249152 1750 dbSNP
rs988816801 1753 dbSNP
rs1211050899 1762 dbSNP
rs1045943158 1763 dbSNP
rs1482291332 1765 dbSNP
rs1185813002 1770 dbSNP
rs957467096 1774 dbSNP
rs549353668 1776 dbSNP
rs1243563881 1783 dbSNP
rs111442821 1784 dbSNP
rs1431111401 1789 dbSNP
rs1414854029 1797 dbSNP
rs1174855863 1798 dbSNP
rs1001663821 1803 dbSNP
rs148811971 1804 dbSNP
rs540940820 1809 dbSNP
rs1369463843 1819 dbSNP
rs1409730050 1828 dbSNP
rs1287049387 1831 dbSNP
rs936059507 1834 dbSNP
rs1024472994 1835 dbSNP
rs1300785073 1836 dbSNP
rs193269987 1847 dbSNP
rs1206955977 1850 dbSNP
rs1275413440 1856 dbSNP
rs977481099 1863 dbSNP
rs1314092784 1869 dbSNP
rs897391659 1869 dbSNP
rs10203064 1871 dbSNP
rs76888223 1878 dbSNP
rs76292387 1879 dbSNP
rs1410860903 1880 dbSNP
rs4261731 1880 dbSNP
rs879200943 1881 dbSNP
rs79623202 1888 dbSNP
rs199604148 1889 dbSNP
rs111272589 1891 dbSNP
rs1427300209 1891 dbSNP
rs1203492028 1893 dbSNP
rs1216514346 1893 dbSNP
rs575282409 1897 dbSNP
rs1400302958 1905 dbSNP
rs1344444619 1907 dbSNP
rs1293770074 1909 dbSNP
rs1452105151 1910 dbSNP
rs1220818727 1913 dbSNP
rs1244742788 1914 dbSNP
rs555534004 1917 dbSNP
rs1389194229 1918 dbSNP
rs529830794 1918 dbSNP
rs1164943939 1923 dbSNP
rs72950385 1926 dbSNP
rs984282078 1927 dbSNP
rs1437750299 1928 dbSNP
rs1169661196 1929 dbSNP
rs1364736529 1930 dbSNP
rs763052287 1930 dbSNP
rs1433250832 1937 dbSNP
rs1408084641 1940 dbSNP
rs1286016806 1945 dbSNP
rs1357203710 1951 dbSNP
rs1421463395 1952 dbSNP
rs572709462 1952 dbSNP
rs1040190691 1956 dbSNP
rs1209140309 1961 dbSNP
rs1246964374 1969 dbSNP
rs1185117478 1971 dbSNP
rs1237518100 1978 dbSNP
rs1025809083 1992 dbSNP
rs944650681 2001 dbSNP
rs143818416 2005 dbSNP
rs1197475746 2007 dbSNP
rs185297506 2008 dbSNP
rs1024526047 2009 dbSNP
rs989239255 2012 dbSNP
rs4407252 2013 dbSNP
rs1204512882 2018 dbSNP
rs1368564075 2022 dbSNP
rs894636922 2022 dbSNP
rs75832376 2023 dbSNP
rs1352263674 2029 dbSNP
rs980194556 2031 dbSNP
rs970095782 2033 dbSNP
rs1229003583 2041 dbSNP
rs1267248832 2042 dbSNP
rs1326861242 2045 dbSNP
rs1205126133 2049 dbSNP
rs936157907 2053 dbSNP
rs1441275877 2064 dbSNP
rs1024922757 2066 dbSNP
rs992980989 2071 dbSNP
rs1234179128 2076 dbSNP
rs1473850278 2080 dbSNP
rs192903189 2086 dbSNP
rs1411650518 2092 dbSNP
rs1260438124 2097 dbSNP
rs1403199675 2100 dbSNP
rs1413917184 2102 dbSNP
rs1332272750 2103 dbSNP
rs1015807869 2110 dbSNP
rs1372556720 2114 dbSNP
rs1219610484 2119 dbSNP
rs1345220759 2121 dbSNP
rs1348338383 2138 dbSNP
rs1235156509 2139 dbSNP
rs1004559427 2144 dbSNP
rs887476428 2148 dbSNP
rs4260249 2150 dbSNP
rs922569273 2151 dbSNP
rs975348000 2152 dbSNP
rs995951033 2159 dbSNP
rs1388082761 2163 dbSNP
rs1483120089 2165 dbSNP
rs1367709336 2168 dbSNP
rs900238173 2172 dbSNP
rs1440016771 2177 dbSNP
rs1201474456 2178 dbSNP
rs1378646869 2178 dbSNP
rs1356170519 2180 dbSNP
rs1171182899 2181 dbSNP
rs1392052181 2188 dbSNP
rs1307270434 2194 dbSNP
rs1430525066 2194 dbSNP
rs538329580 2202 dbSNP
rs1388508377 2204 dbSNP
rs944534179 2209 dbSNP
rs1323965716 2225 dbSNP
rs569301797 2227 dbSNP
rs1230585099 2228 dbSNP
rs1299391621 2230 dbSNP
rs1174567238 2231 dbSNP
rs1052997620 2239 dbSNP
rs1209195772 2243 dbSNP
rs951288460 2244 dbSNP
rs1435118405 2246 dbSNP
rs1025421028 2248 dbSNP
rs935916008 2252 dbSNP
rs981797937 2255 dbSNP
rs549462309 2260 dbSNP
rs756540418 2262 dbSNP
rs1212217358 2266 dbSNP
rs529429499 2269 dbSNP
rs1451439147 2277 dbSNP
rs1023216745 2278 dbSNP
rs1013127535 2283 dbSNP
rs948818259 2284 dbSNP
rs567088790 2285 dbSNP
rs1168026486 2295 dbSNP
rs1033674384 2303 dbSNP
rs1199777923 2305 dbSNP
rs917316965 2307 dbSNP
rs547289651 2312 dbSNP
rs761105130 2327 dbSNP
rs993407327 2331 dbSNP
rs1384892507 2336 dbSNP
rs187172850 2338 dbSNP
rs564082590 2341 dbSNP
rs1294758007 2343 dbSNP
rs901178102 2346 dbSNP
rs543816318 2347 dbSNP
rs1266583927 2352 dbSNP
rs1356013444 2357 dbSNP
rs909840387 2358 dbSNP
rs942688376 2358 dbSNP
rs774435958 2361 dbSNP
rs1048771069 2365 dbSNP
rs984412433 2370 dbSNP
rs113946441 2377 dbSNP
rs374549781 2377 dbSNP
rs1188117665 2379 dbSNP
rs1367823379 2380 dbSNP
rs1456143718 2381 dbSNP
rs750818714 2385 dbSNP
rs952923305 2387 dbSNP
rs149684281 2395 dbSNP
rs1389187720 2405 dbSNP
rs1456348474 2406 dbSNP
rs1318184996 2408 dbSNP
rs75085685 2411 dbSNP
rs981827585 2417 dbSNP
rs1396115781 2419 dbSNP
rs768077886 2427 dbSNP
rs531807805 2429 dbSNP
rs995815299 2430 dbSNP
rs1467814634 2432 dbSNP
rs1378400814 2434 dbSNP
rs115261463 2435 dbSNP
rs182481903 2442 dbSNP
rs1208293728 2446 dbSNP
rs548396440 2449 dbSNP
rs189832069 2451 dbSNP
rs957921460 2452 dbSNP
rs1255626613 2457 dbSNP
rs1474181061 2458 dbSNP
rs764675099 2464 dbSNP
rs1412404024 2475 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uucAAUAUGGUUUAUACGGUCc 5'
             || | :|   |||||||| 
Target 5' ---UUUUUUC---UAUGCCAGg 3'
 		1 - 16
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000541405.1 | 3UTR | UUUUUUCUAUGCCAGGUCUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
40 hsa-miR-4720-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT064869 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT099937 SOX4 SRY-box 4 2 2
MIRT204534 SLC39A10 solute carrier family 39 member 10 2 4
MIRT221679 ZNRF2 zinc and ring finger 2 2 2
MIRT296659 MRGBP MRG domain binding protein 2 6
MIRT331634 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT337078 RER1 retention in endoplasmic reticulum sorting receptor 1 2 2
MIRT497580 PTCHD4 patched domain containing 4 2 2
MIRT498838 NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 2 4
MIRT502561 EBAG9 estrogen receptor binding site associated, antigen, 9 2 2
MIRT508128 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT511875 GOLGA7 golgin A7 2 6
MIRT512924 UBL4A ubiquitin like 4A 2 2
MIRT513833 KLHL15 kelch like family member 15 2 6
MIRT515889 FAM182B family with sequence similarity 182 member B 2 2
MIRT520201 WASL Wiskott-Aldrich syndrome like 2 2
MIRT526045 GMDS GDP-mannose 4,6-dehydratase 2 2
MIRT533601 TNPO1 transportin 1 2 2
MIRT535539 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 6
MIRT541150 PABPC1 poly(A) binding protein cytoplasmic 1 2 4
MIRT549609 TMEM101 transmembrane protein 101 2 2
MIRT552630 ZBTB41 zinc finger and BTB domain containing 41 2 2
MIRT555503 PNISR PNN interacting serine and arginine rich protein 2 2
MIRT560225 PCNA proliferating cell nuclear antigen 2 2
MIRT561671 RAPGEF2 Rap guanine nucleotide exchange factor 2 2 2
MIRT562103 ITGB1 integrin subunit beta 1 2 2
MIRT570710 E2F3 E2F transcription factor 3 2 2
MIRT570802 CKAP2L cytoskeleton associated protein 2 like 2 2
MIRT615261 DPF2 double PHD fingers 2 2 2
MIRT615389 ZNF747 zinc finger protein 747 2 2
MIRT616621 KCNJ11 potassium voltage-gated channel subfamily J member 11 2 4
MIRT641085 ZKSCAN2 zinc finger with KRAB and SCAN domains 2 2 2
MIRT654971 PLEKHA2 pleckstrin homology domain containing A2 2 2
MIRT667033 PDE3A phosphodiesterase 3A 2 2
MIRT677217 RASSF6 Ras association domain family member 6 2 2
MIRT699243 SLC6A8 solute carrier family 6 member 8 2 2
MIRT711673 TRMT5 tRNA methyltransferase 5 2 2
MIRT713922 CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 2 2
MIRT722736 BRMS1 breast cancer metastasis suppressor 1 2 2
MIRT724997 CDC27 cell division cycle 27 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4720-5p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-4720-5p Yuanhuadine 6440572 sensitive High Non-Small Cell Lung Cancer cell line (PC-9)
hsa-miR-4720-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4720-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4720-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-4720-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-4720-5p Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-4720-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)

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