ID	Duplex structure	Position	Score	MFE
1	miRNA 3' gacacccccguccUCCCCgc 5' ||||| Target 5' gccaaaggttctcAGGGGag 3'	106 - 125	100.00	-10.80

Mutant ID	Mutant Position	Mutant Source
COSN30531354	13	COSMIC
COSN30576549	38	COSMIC
COSN30496365	84	COSMIC
COSN30140656	117	COSMIC
COSN30533410	123	COSMIC
COSN1232445	204	COSMIC
COSN18717223	242	COSMIC
COSN26438689	282	COSMIC
COSN5495410	308	COSMIC
COSN20097756	573	COSMIC
COSN28377295	670	COSMIC
COSN16129982	815	COSMIC
COSN17183223	852	COSMIC
COSN20090712	986	COSMIC
COSN20967790	1881	COSMIC
COSN18009259	2189	COSMIC

Mutant ID	Mutant Position	Mutant Source
rs757351208	3	dbSNP
rs751598986	4	dbSNP
rs1258470489	7	dbSNP
rs1213371918	10	dbSNP
rs764701504	16	dbSNP
rs1024583310	17	dbSNP
rs375883561	18	dbSNP
rs779696224	18	dbSNP
rs753166697	22	dbSNP
rs765519201	29	dbSNP
rs1462778954	30	dbSNP
rs1352794725	34	dbSNP
rs1333462681	35	dbSNP
rs759915037	36	dbSNP
rs543139683	49	dbSNP
rs1441842094	53	dbSNP
rs1303778683	55	dbSNP
rs1381848309	60	dbSNP
rs1243427147	62	dbSNP
rs1031301107	68	dbSNP
rs1000793142	74	dbSNP
rs1218388815	90	dbSNP
rs1394683522	93	dbSNP
rs1293159515	97	dbSNP
rs903667193	109	dbSNP
rs1319225382	113	dbSNP
rs886738815	119	dbSNP
rs1447900600	121	dbSNP
rs1259500416	125	dbSNP
rs577299882	129	dbSNP
rs1048068602	133	dbSNP
rs1203443122	136	dbSNP
rs1007636740	149	dbSNP
rs1484090333	153	dbSNP
rs1212340371	157	dbSNP
rs926864803	160	dbSNP
rs889229618	166	dbSNP
rs1172903381	168	dbSNP
rs1051766244	203	dbSNP
rs1417533687	206	dbSNP
rs1409572711	208	dbSNP
rs780120984	209	dbSNP
rs769782590	215	dbSNP
rs933349560	238	dbSNP
rs897831553	241	dbSNP
rs750731320	242	dbSNP
rs550512576	249	dbSNP
rs1312654652	264	dbSNP
rs942315308	269	dbSNP
rs1279512557	270	dbSNP
rs757613282	273	dbSNP
rs918112753	276	dbSNP
rs1278835513	288	dbSNP
rs751399274	288	dbSNP
rs2709417	291	dbSNP
rs1431236163	304	dbSNP
rs1032318470	310	dbSNP
rs979439132	312	dbSNP
rs947787300	313	dbSNP
rs1475097141	324	dbSNP
rs1191858734	350	dbSNP
rs534328117	353	dbSNP
rs991931143	355	dbSNP
rs953385873	364	dbSNP
rs571968513	366	dbSNP
rs555417194	380	dbSNP
rs535739376	382	dbSNP
rs1030685339	386	dbSNP
rs1345146426	388	dbSNP
rs979731448	393	dbSNP
rs569895305	395	dbSNP
rs996802198	397	dbSNP
rs900973700	416	dbSNP
rs1394651716	422	dbSNP
rs1302389126	448	dbSNP
rs1218547116	462	dbSNP
rs1281991699	469	dbSNP
rs1169352892	472	dbSNP
rs1446361017	488	dbSNP
rs1222390028	497	dbSNP
rs1019869852	498	dbSNP
rs549985842	504	dbSNP
rs1193284216	508	dbSNP
rs1381188905	531	dbSNP
rs1421245336	532	dbSNP
rs765946483	537	dbSNP
rs1441880008	538	dbSNP
rs375647863	538	dbSNP
rs539610242	538	dbSNP
rs571791877	544	dbSNP
rs1384795141	545	dbSNP
rs1186695763	547	dbSNP
rs889195084	550	dbSNP
rs995116096	551	dbSNP
rs1438223697	552	dbSNP
rs1324744232	559	dbSNP
rs1030796027	570	dbSNP
rs1475972949	573	dbSNP
rs190467441	575	dbSNP
rs1252761125	584	dbSNP
rs1349848154	586	dbSNP
rs201525600	587	dbSNP
rs200593695	588	dbSNP
rs1045281975	589	dbSNP
rs1467164019	589	dbSNP
rs398060988	589	dbSNP
rs57895626	589	dbSNP
rs768562083	589	dbSNP
rs771294185	589	dbSNP
rs2252982	590	dbSNP
rs1470231934	591	dbSNP
rs918051276	592	dbSNP
rs1473400509	595	dbSNP
rs1203957668	620	dbSNP
rs1305793397	627	dbSNP
rs1416364242	647	dbSNP
rs1036377567	650	dbSNP
rs566055882	651	dbSNP
rs112938344	656	dbSNP
rs888051968	657	dbSNP
rs145143490	661	dbSNP
rs1045202516	669	dbSNP
rs1326577060	681	dbSNP
rs1442751596	691	dbSNP
rs925342628	693	dbSNP
rs529520955	694	dbSNP
rs918095237	695	dbSNP
rs992295628	699	dbSNP
rs1297497529	700	dbSNP
rs58092287	705	dbSNP
rs1439421725	710	dbSNP
rs1443316531	711	dbSNP
rs1190064321	712	dbSNP
rs1255940279	716	dbSNP
rs1355750130	718	dbSNP
rs563572549	719	dbSNP
rs201773577	720	dbSNP
rs1463169665	721	dbSNP
rs923591687	727	dbSNP
rs921937374	733	dbSNP
rs1172168310	735	dbSNP
rs1395358432	737	dbSNP
rs1414767907	744	dbSNP
rs1455825937	747	dbSNP
rs979145738	754	dbSNP
rs1278897600	756	dbSNP
rs1328320299	758	dbSNP
rs186558381	762	dbSNP
rs1250910984	764	dbSNP
rs1479723281	767	dbSNP
rs1213461795	774	dbSNP
rs774527015	785	dbSNP
rs985380606	786	dbSNP
rs58995239	789	dbSNP
rs1029514253	790	dbSNP
rs965694143	793	dbSNP
rs1190417883	795	dbSNP
rs112142986	801	dbSNP
rs1019416436	802	dbSNP
rs1373450258	808	dbSNP
rs1236259338	843	dbSNP
rs1433994239	844	dbSNP
rs1348266013	846	dbSNP
rs190885366	852	dbSNP
rs1306260823	855	dbSNP
rs1298691216	866	dbSNP
rs1387079539	869	dbSNP
rs371022046	871	dbSNP
rs1295027731	872	dbSNP
rs1221972470	874	dbSNP
rs1236830132	874	dbSNP
rs1004440825	877	dbSNP
rs1374957579	881	dbSNP
rs1298267186	883	dbSNP
rs1217833109	886	dbSNP
rs1262956085	889	dbSNP
rs1485183218	891	dbSNP
rs1202854334	895	dbSNP
rs1260508426	905	dbSNP
rs571995487	908	dbSNP
rs1476766278	915	dbSNP
rs1413559152	916	dbSNP
rs1373273271	917	dbSNP
rs1392915005	922	dbSNP
rs951241609	923	dbSNP
rs2464982	925	dbSNP
rs1437028172	926	dbSNP
rs1396040089	928	dbSNP
rs1159105487	929	dbSNP
rs1288340836	930	dbSNP
rs1391590541	932	dbSNP
rs1443231243	940	dbSNP
rs1370546004	943	dbSNP
rs1241246995	949	dbSNP
rs1309694053	950	dbSNP
rs1315648468	953	dbSNP
rs1239026446	954	dbSNP
rs1158230940	959	dbSNP
rs1162886664	959	dbSNP
rs1177554371	959	dbSNP
rs1215046437	959	dbSNP
rs1234586657	959	dbSNP
rs1250692868	959	dbSNP
rs1252465293	959	dbSNP
rs1259597965	959	dbSNP
rs1300247361	959	dbSNP
rs1314003042	959	dbSNP
rs1333676703	959	dbSNP
rs1337602837	959	dbSNP
rs1371683284	959	dbSNP
rs1394025792	959	dbSNP
rs1417203357	959	dbSNP
rs1418511407	959	dbSNP
rs1447876304	959	dbSNP
rs1463024334	959	dbSNP
rs1467804769	959	dbSNP
rs1468507378	959	dbSNP
rs57522071	959	dbSNP
rs767632290	959	dbSNP
rs1204826587	960	dbSNP
rs1252729857	960	dbSNP
rs1479505763	961	dbSNP
rs1176420630	962	dbSNP
rs1258055710	963	dbSNP
rs1476186189	965	dbSNP
rs1185885762	968	dbSNP
rs1417311396	969	dbSNP
rs1410719515	970	dbSNP
rs1172752199	976	dbSNP
rs1417836071	984	dbSNP
rs1461749652	985	dbSNP
rs1171406142	986	dbSNP
rs1177853527	988	dbSNP
rs1290869377	989	dbSNP
rs1413524052	989	dbSNP
rs1354225341	996	dbSNP
rs1485360856	1003	dbSNP
rs112431566	1004	dbSNP
rs1266909963	1004	dbSNP
rs1280856298	1004	dbSNP
rs1305405156	1004	dbSNP
rs1208693175	1008	dbSNP
rs1256756633	1012	dbSNP
rs1018271364	1013	dbSNP
rs1188376517	1024	dbSNP
rs1417556768	1024	dbSNP
rs1428198587	1030	dbSNP
rs1213259419	1033	dbSNP
rs1208469683	1047	dbSNP
rs1377689563	1048	dbSNP
rs71429778	1051	dbSNP
rs1433277721	1064	dbSNP
rs1485898349	1073	dbSNP
rs1489667207	1098	dbSNP
rs71429777	1100	dbSNP
rs1430736707	1110	dbSNP
rs1274416406	1156	dbSNP
rs1359414073	1165	dbSNP
rs1259923205	1197	dbSNP
rs1303836742	1200	dbSNP
rs1349735402	1214	dbSNP
rs1213317546	1276	dbSNP
rs1318664905	1279	dbSNP
rs1307571538	1324	dbSNP
rs1232175770	1327	dbSNP
rs1447521991	1340	dbSNP
rs1218037446	1365	dbSNP
rs1240478881	1401	dbSNP
rs1353001228	1408	dbSNP
rs1294792559	1411	dbSNP
rs1415016083	1425	dbSNP
rs1485645861	1436	dbSNP
rs1403429593	1439	dbSNP
rs1288667349	1447	dbSNP
rs1397137992	1448	dbSNP
rs1451989622	1459	dbSNP
rs1347491439	1470	dbSNP
rs868202546	1499	dbSNP
rs1474949075	1513	dbSNP
rs1415725668	1520	dbSNP
rs1190415340	1539	dbSNP
rs1475666996	1544	dbSNP
rs1261221492	1552	dbSNP
rs1184593289	1562	dbSNP
rs1486696574	1564	dbSNP
rs1261295134	1569	dbSNP
rs868043328	1570	dbSNP
rs1332119309	1573	dbSNP
rs1274495802	1576	dbSNP
rs1233299677	1579	dbSNP
rs1325491828	1599	dbSNP
rs1292943227	1616	dbSNP
rs1372745973	1630	dbSNP
rs1380904190	1651	dbSNP
rs1274101451	1654	dbSNP
rs1351282115	1714	dbSNP
rs1225429867	1716	dbSNP
rs865967616	1723	dbSNP
rs1214412527	1724	dbSNP
rs1255047119	1770	dbSNP
rs1321853473	1777	dbSNP
rs1461372899	1792	dbSNP
rs1392445545	1809	dbSNP
rs1233868774	1817	dbSNP
rs868472128	1851	dbSNP
rs1157300180	1859	dbSNP
rs1407922692	1865	dbSNP
rs1456199620	1877	dbSNP
rs1458440613	1881	dbSNP
rs1396220443	1886	dbSNP
rs1438335084	1895	dbSNP
rs1322612435	1896	dbSNP
rs1336083333	1900	dbSNP
rs1444134248	1904	dbSNP
rs1277637561	1905	dbSNP
rs1349801906	1905	dbSNP
rs1233974024	1908	dbSNP
rs1275188241	1912	dbSNP
rs1372743010	1920	dbSNP
rs1439870163	1923	dbSNP
rs1232745284	1934	dbSNP
rs1188033402	1935	dbSNP
rs1475860581	1935	dbSNP
rs1419437762	1936	dbSNP
rs1191277495	1937	dbSNP
rs1459439022	1937	dbSNP
rs1430130637	1942	dbSNP
rs1322545479	1944	dbSNP
rs867685487	1945	dbSNP
rs865905337	1947	dbSNP
rs1365797531	1949	dbSNP
rs1326684022	1951	dbSNP
rs1349782070	1952	dbSNP
rs1415373686	1952	dbSNP
rs1460992838	1952	dbSNP
rs1366899747	1955	dbSNP
rs1244187647	1959	dbSNP
rs1270933152	1966	dbSNP
rs1341746593	1971	dbSNP
rs1467096913	1980	dbSNP
rs1254737959	2001	dbSNP
rs1213800154	2011	dbSNP
rs1338115438	2013	dbSNP
rs1213592461	2016	dbSNP
rs1249308352	2017	dbSNP
rs1229117360	2024	dbSNP
rs1309699294	2026	dbSNP
rs1298779209	2027	dbSNP
rs1440542643	2029	dbSNP
rs1369472512	2032	dbSNP
rs1328457302	2033	dbSNP
rs1387476259	2035	dbSNP
rs1395828782	2040	dbSNP
rs1166443000	2041	dbSNP
rs1463712323	2044	dbSNP
rs1390960883	2045	dbSNP
rs868808166	2051	dbSNP
rs1452293235	2057	dbSNP
rs866931815	2058	dbSNP
rs1199459024	2060	dbSNP
rs1436761050	2061	dbSNP
rs1247796941	2068	dbSNP
rs1197242828	2071	dbSNP
rs1480761761	2072	dbSNP
rs1279115500	2079	dbSNP
rs1369760949	2079	dbSNP
rs1234049395	2090	dbSNP
rs1346144217	2093	dbSNP
rs865870461	2099	dbSNP
rs868573409	2114	dbSNP
rs1373574590	2117	dbSNP
rs1319146724	2128	dbSNP
rs1328415396	2128	dbSNP
rs1335311293	2128	dbSNP
rs1225589109	2139	dbSNP
rs1326953699	2141	dbSNP
rs1297180017	2155	dbSNP
rs1393148829	2156	dbSNP
rs1236971641	2157	dbSNP
rs1371433129	2163	dbSNP
rs1312445982	2164	dbSNP
rs1483247102	2165	dbSNP
rs1199375491	2168	dbSNP
rs1432681032	2174	dbSNP
rs1377015832	2175	dbSNP
rs1448338776	2177	dbSNP
rs1186237768	2180	dbSNP
rs1173154952	2181	dbSNP
rs1469551582	2182	dbSNP
rs1361934948	2183	dbSNP
rs1183397955	2187	dbSNP
rs1472605661	2188	dbSNP
rs1256430994	2189	dbSNP
rs1208241458	2192	dbSNP
rs1393193171	2199	dbSNP
rs1484935811	2200	dbSNP
rs1281155295	2202	dbSNP
rs1201335924	2203	dbSNP
rs1350600541	2205	dbSNP
rs1278249631	2207	dbSNP
rs1241299034	2208	dbSNP
rs1320069789	2212	dbSNP
rs1351154878	2216	dbSNP
rs1292946716	2217	dbSNP
rs866692445	2220	dbSNP
rs1377102934	2221	dbSNP
rs1334581136	2222	dbSNP
rs1301769278	2223	dbSNP
rs1312101325	2225	dbSNP
rs1399828643	2226	dbSNP
rs1382726733	2227	dbSNP
rs1160202836	2234	dbSNP
rs1457349262	2237	dbSNP
rs1416520759	2238	dbSNP
rs1468696692	2239	dbSNP
rs1185429741	2240	dbSNP
rs1195257163	2241	dbSNP
rs1475992543	2244	dbSNP
rs1237629530	2248	dbSNP
rs1188722105	2249	dbSNP
rs1365475337	2249	dbSNP
rs1451633452	2250	dbSNP
rs1446731190	2255	dbSNP
rs1282823813	2256	dbSNP
rs1463257018	2256	dbSNP
rs1211089618	2257	dbSNP
rs1330000357	2258	dbSNP
rs1272609622	2259	dbSNP
rs1231468453	2264	dbSNP
rs1357609855	2265	dbSNP
rs1284952273	2266	dbSNP
rs1429829817	2268	dbSNP
rs1324439079	2269	dbSNP
rs1320286424	2270	dbSNP
rs1435713022	2274	dbSNP
rs1393570712	2275	dbSNP
rs1162182104	2276	dbSNP
rs1462524895	2278	dbSNP
rs1488000646	2279	dbSNP
rs866335194	2283	dbSNP
rs1166931805	2285	dbSNP
rs1475313529	2287	dbSNP
rs1240712655	2289	dbSNP
rs1191115709	2290	dbSNP
rs1471600553	2290	dbSNP
rs1465754740	2291	dbSNP
rs1252847272	2292	dbSNP
rs1211936093	2315	dbSNP
rs1323560761	2316	dbSNP
rs1418715808	2317	dbSNP
rs1476245049	2319	dbSNP
rs1290910773	2320	dbSNP
rs1214201245	2325	dbSNP
rs1162884844	2329	dbSNP
rs1349531129	2335	dbSNP
rs200081603	2335	dbSNP
rs1462757424	2337	dbSNP
rs1337273579	2342	dbSNP
rs1300338263	2344	dbSNP
rs1299565220	2346	dbSNP
rs1435463065	2347	dbSNP
rs1370204542	2348	dbSNP
rs1323757173	2352	dbSNP
rs1442523621	2353	dbSNP
rs1349919442	2360	dbSNP
rs1327846637	2361	dbSNP
rs1409807734	2364	dbSNP
rs1287126123	2365	dbSNP
rs1355500003	2366	dbSNP
rs1407842741	2372	dbSNP
rs1310048697	2374	dbSNP
rs1320809822	2375	dbSNP
rs1421125651	2377	dbSNP
rs1170882977	2382	dbSNP
rs1450433735	2383	dbSNP
rs1482014529	2383	dbSNP
rs1395064171	2392	dbSNP
rs1192273342	2393	dbSNP
rs1489546076	2397	dbSNP
rs1476195373	2401	dbSNP
rs1180199707	2402	dbSNP
rs868842256	2409	dbSNP
rs1429399895	2413	dbSNP
rs1203838820	2428	dbSNP
rs1436298594	2445	dbSNP
rs1429552581	2453	dbSNP
rs1276993982	2477	dbSNP
rs1228900497	2485	dbSNP
rs1346847973	2489	dbSNP
rs1301205206	2490	dbSNP
rs1220866376	2491	dbSNP
rs1367761777	2499	dbSNP
rs1300624847	2501	dbSNP
rs1278456907	2517	dbSNP
rs1439309920	2518	dbSNP
rs1372055419	2520	dbSNP
rs1227409675	2522	dbSNP
rs1280878188	2523	dbSNP
rs1308208131	2542	dbSNP
rs1430845937	2568	dbSNP
rs1375218417	2570	dbSNP
rs1237027652	2603	dbSNP
rs1486300510	2638	dbSNP
rs1172380586	2642	dbSNP
rs1435440905	2643	dbSNP
rs1188470467	2687	dbSNP
rs1246452056	2787	dbSNP
rs1449169831	2800	dbSNP
rs1426410373	2896	dbSNP
rs1397414132	2916	dbSNP
rs1413312123	2936	dbSNP
rs1176724229	2958	dbSNP
rs1468626461	2975	dbSNP
rs1173303710	2979	dbSNP
rs1358029969	3013	dbSNP
rs1254308956	3016	dbSNP
rs1206094701	3017	dbSNP
rs1322069249	3049	dbSNP
rs1362588369	3074	dbSNP
rs1485258640	3075	dbSNP
rs1310252893	3077	dbSNP
rs1303958281	3081	dbSNP
rs1323174183	3082	dbSNP
rs1244974771	3083	dbSNP
rs1259640080	3088	dbSNP
rs1463203843	3096	dbSNP
rs1210054545	3098	dbSNP
rs1349938499	3099	dbSNP
rs1461248081	3100	dbSNP
rs1182160302	3101	dbSNP
rs1233371156	3109	dbSNP
rs542181104	3114	dbSNP
rs576422187	3118	dbSNP
rs556469424	3119	dbSNP
rs539647702	3124	dbSNP
rs570619770	3126	dbSNP
rs1217448585	3152	dbSNP
rs201100027	3154	dbSNP
rs558009075	3174	dbSNP
rs535113144	3178	dbSNP
rs528802722	3181	dbSNP
rs1277903200	3186	dbSNP
rs1211902138	3196	dbSNP
rs1312703750	3200	dbSNP
rs1306151093	3203	dbSNP
rs1246414729	3204	dbSNP
rs1464657726	3224	dbSNP
rs62191484	3225	dbSNP
rs1221598644	3230	dbSNP
rs1351766073	3246	dbSNP
rs1191072676	3252	dbSNP
rs1255326848	3252	dbSNP
rs1409372055	3252	dbSNP
rs879717925	3252	dbSNP
rs1400714473	3253	dbSNP
rs1288665566	3254	dbSNP
rs180737398	3254	dbSNP
rs189932776	3259	dbSNP
rs1385975887	3260	dbSNP
rs1456425475	3262	dbSNP
rs1326300164	3268	dbSNP
rs565966637	3269	dbSNP
rs549341817	3270	dbSNP
rs529213356	3271	dbSNP
rs200741071	3272	dbSNP
rs199667866	3273	dbSNP
rs1201623045	3274	dbSNP
rs1332567892	3274	dbSNP
rs201271790	3274	dbSNP
rs1284823771	3275	dbSNP
rs1353120498	3278	dbSNP
rs1274120429	3286	dbSNP
rs1374049235	3288	dbSNP
rs1301467192	3290	dbSNP
rs1266366175	3301	dbSNP
rs997980744	3326	dbSNP
rs564700649	3329	dbSNP
rs1328708930	3330	dbSNP
rs1214510288	3332	dbSNP
rs1467867850	3335	dbSNP
rs1450175924	3337	dbSNP
rs1221301520	3348	dbSNP
rs1360275645	3354	dbSNP
rs1233963788	3364	dbSNP
rs897938009	3369	dbSNP
rs376712903	3385	dbSNP
rs527366553	3386	dbSNP
rs887787012	3404	dbSNP
rs1414267885	3405	dbSNP
rs141109231	3410	dbSNP
rs995250453	3412	dbSNP
rs1355011253	3420	dbSNP
rs1045251421	3431	dbSNP
rs1044712516	3432	dbSNP
rs1013812199	3439	dbSNP
rs1233991886	3446	dbSNP
rs1286106629	3447	dbSNP
rs1354595333	3448	dbSNP
rs541868526	3461	dbSNP
rs1274209162	3463	dbSNP
rs1260123363	3468	dbSNP
rs896742997	3471	dbSNP
rs1251761382	3472	dbSNP
rs1330675976	3484	dbSNP
rs1188056373	3486	dbSNP
rs2551950	3489	dbSNP
rs1232083405	3492	dbSNP
rs935477227	3498	dbSNP
rs1056664718	3506	dbSNP
rs116333731	3507	dbSNP
rs1043801210	3523	dbSNP
rs1314375283	3535	dbSNP
rs932057916	3538	dbSNP
rs1338903976	3539	dbSNP
rs1398211072	3540	dbSNP
rs923755615	3548	dbSNP
rs1043406554	3554	dbSNP
rs976503135	3559	dbSNP
rs1226670847	3560	dbSNP
rs946328797	3561	dbSNP
rs530401403	3562	dbSNP
rs1349326292	3567	dbSNP
rs966100268	3572	dbSNP
rs1355563275	3602	dbSNP
rs1257703143	3604	dbSNP
rs910891413	3610	dbSNP
rs1186336783	3622	dbSNP
rs546109462	3643	dbSNP
rs185282742	3648	dbSNP
rs1242350563	3650	dbSNP
rs1451025093	3666	dbSNP
rs540203891	3666	dbSNP
rs1389466233	3668	dbSNP
rs1435318874	3672	dbSNP
rs1433506648	3673	dbSNP
rs1391392595	3681	dbSNP
rs1400108471	3684	dbSNP
rs1395550661	3686	dbSNP
rs985349359	3688	dbSNP
rs533007510	3697	dbSNP
rs1491439286	3698	dbSNP
rs534837842	3710	dbSNP
rs1424246273	3711	dbSNP
rs564816692	3714	dbSNP
rs1236015327	3730	dbSNP
rs114846295	3732	dbSNP
rs151077304	3733	dbSNP
rs951209372	3762	dbSNP
rs758937615	3770	dbSNP
rs1184500384	3781	dbSNP
rs962435576	3784	dbSNP
rs1247229177	3788	dbSNP
rs969127158	3802	dbSNP
rs1023270057	3806	dbSNP
rs1248528870	3810	dbSNP
rs1176699303	3813	dbSNP
rs1212552184	3821	dbSNP
rs1459083320	3823	dbSNP
rs535457446	3824	dbSNP
rs1014976862	3825	dbSNP
rs896174878	3827	dbSNP
rs1054941	3855	dbSNP
rs1031665646	3856	dbSNP
rs999791592	3860	dbSNP
rs1006264798	3865	dbSNP
rs903986008	3869	dbSNP
rs1372117433	3871	dbSNP
rs1043938425	3875	dbSNP
rs952024589	3928	dbSNP
rs1299733187	3929	dbSNP
rs1331101799	3932	dbSNP

- Cell, 2010

RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.