miRTarBase - #MIRT573149


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pre-miRNA Information
pre-miRNA hsa-mir-452   
Genomic Coordinates chrX: 151959628 - 151959712
Synonyms MIRN452, hsa-mir-452, MIR452
Description Homo sapiens miR-452 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies . The 5' end of the miRNA may be offset with respect to previous annotations.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-452-3p
Sequence 58| CUCAUCUGCAAAGAAGUAAGUG |79
Evidence Experimental
Experiments Array-cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 12 X - 151959644 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs757928550 3 dbSNP
rs1324216965 6 dbSNP
rs1390793899 13 dbSNP
rs899383242 17 dbSNP
rs747858567 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ITGA9   
Synonyms ALPHA-RLC, ITGA4L, RLC
Description integrin subunit alpha 9
Transcript NM_002207   
Expression
Putative miRNA Targets on ITGA9
3'UTR of ITGA9
(miRNA target sites are highlighted)		 
>ITGA9|NM_002207|3'UTR
   1 GCTGCCACACCAGTCACATGACCTGATCACTAGCCTGTCATCCTTGGTCTTTGTATCTTCCATATTTGGAAGAAAAAAAT
  81 CTTCTCCAGATTTTTCGGAGGCCCCACTGATGCTGTTCTCTTCTTCATTCTATCAAGCCCAGGTGCCAGCCTGAGGCAGC
 161 CACTTCGGCCAGGTCACACGACCGGGGCCAGCACCACTTCCTTTAAAGATGAACTCTGAACTTTGGAGAGTGAGCTACAG
 241 AGCCGAGCAATATTTATGGATGCAACACGCATGGTCAACCCTCAGGGGAAAACTGTTACCTAAAGTATTTTTATAAATAT
 321 AAGCCTTTTATACTGATTATGTCTTTTATATTTGTATCGATGTTTTATTATTTCTATTAAATAGTTATATAATTCACTCA
 401 AGCACTGATATCTGGCCTAAAATCTTGGAAGTACATGTCCATGAATACAAATTTTAAAGGATGAAAATCTTACCGTACTT
 481 TGGAACTTGCTGTTTAAAAAGACAGATGAAATAAGTTGAAGAAACCTCATGTAATGAATCCACCAGGCTGGCAGTGGTGC
 561 ATATAAACTGTGGGTGTGGCAAGACCCCGAAGACATTTCACATCTTTATCGCCTCGATCAAGTGTGGAGTCACATGCTAA
 641 TGTGTGCTAAAGAACTGTAAGTGTTTTTTCATATGTACTTTTCATTGGAAGATTCCCAACAAGAATTTGGATGGAAAACC
 721 TGATCCCTAGCAAGAAGTCTGCTCTGTATCACCTTTATATAGCAGACATGTCACCCTGCTTCTACACAGATGATGGATGA
 801 A
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guGAAUGAAGAAACGUCUACUc 5'
            | |:|||||   ||||||| 
Target 5' acCCTGCTTCTACACAGATGAt 3'
 773 - 794 164.00 -13.90
2 
miRNA  3' guGAAUGAAGAA----AC-GUCUACUc 5'
            |||:|| :||     | ||||||| 
Target 5' aaCTTGCTGTTTAAAAAGACAGATGAa 3'
 484 - 510 154.00 -12.10
3 
miRNA  3' gugaaUGAA-GAAACGUCUACUc 5'
               |||| ||||  |||||| 
Target 5' gcaccACTTCCTTTAAAGATGAa 3'
 191 - 213 137.00 -13.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30501188 6 COSMIC
COSN30146002 26 COSMIC
COSN28849735 39 COSMIC
COSN508796 58 COSMIC
COSN6767333 68 COSMIC
COSN31558933 82 COSMIC
COSN31575573 85 COSMIC
COSN30136796 97 COSMIC
COSN31489092 154 COSMIC
COSN30143187 167 COSMIC
COSN26678749 187 COSMIC
COSN21343238 239 COSMIC
COSN26662718 270 COSMIC
COSN26600454 403 COSMIC
COSN19006398 430 COSMIC
COSN8925474 570 COSMIC
COSN1948702 913 COSMIC
COSN20848576 1035 COSMIC
COSN29475749 1048 COSMIC
COSN29475707 1049 COSMIC
COSN31814059 1884 COSMIC
COSN32062435 2100 COSMIC
COSN1948703 2185 COSMIC
COSN20699244 2449 COSMIC
COSN9550132 2754 COSMIC
COSN22193111 2884 COSMIC
COSN6767334 3011 COSMIC
COSN15885658 3100 COSMIC
COSN5044225 3505 COSMIC
COSN23352198 3716 COSMIC
COSN20693431 4193 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs754808283 2 dbSNP
rs781182278 5 dbSNP
rs747948246 6 dbSNP
rs756415528 6 dbSNP
rs1298873666 7 dbSNP
rs1442849829 9 dbSNP
rs1384728343 10 dbSNP
rs755877875 11 dbSNP
rs1184726150 15 dbSNP
rs1053881614 18 dbSNP
rs777439306 19 dbSNP
rs748899987 22 dbSNP
rs1428857473 26 dbSNP
rs1277000766 31 dbSNP
rs1368683108 35 dbSNP
rs770449623 38 dbSNP
rs376408180 45 dbSNP
rs1264044739 48 dbSNP
rs773676373 52 dbSNP
rs893443555 61 dbSNP
rs1204269385 78 dbSNP
rs1273248607 80 dbSNP
rs139487948 80 dbSNP
rs911581584 91 dbSNP
rs1356609809 97 dbSNP
rs748531031 98 dbSNP
rs111503233 105 dbSNP
rs1246564955 105 dbSNP
rs1381291499 110 dbSNP
rs564791739 115 dbSNP
rs1201423380 116 dbSNP
rs1441226226 122 dbSNP
rs1336190242 130 dbSNP
rs943611148 133 dbSNP
rs1423028500 142 dbSNP
rs970590502 144 dbSNP
rs1460190560 148 dbSNP
rs6789484 151 dbSNP
rs1163378642 157 dbSNP
rs1238941534 158 dbSNP
rs1406438821 161 dbSNP
rs143402730 168 dbSNP
rs1470712892 173 dbSNP
rs1254470916 176 dbSNP
rs958783152 179 dbSNP
rs991559004 180 dbSNP
rs919948259 181 dbSNP
rs952723036 184 dbSNP
rs1174152138 185 dbSNP
rs1048240707 188 dbSNP
rs35239140 209 dbSNP
rs1223185714 211 dbSNP
rs908789623 221 dbSNP
rs1014385127 224 dbSNP
rs1024300895 229 dbSNP
rs1345119363 235 dbSNP
rs944259541 238 dbSNP
rs1041198421 239 dbSNP
rs921409453 245 dbSNP
rs932415934 246 dbSNP
rs1240983211 259 dbSNP
rs1158982797 264 dbSNP
rs1053528802 267 dbSNP
rs773617472 269 dbSNP
rs374304892 270 dbSNP
rs1479214509 273 dbSNP
rs1267749329 287 dbSNP
rs1378406725 291 dbSNP
rs1489173814 299 dbSNP
rs1042733049 303 dbSNP
rs1389184669 319 dbSNP
rs906449537 324 dbSNP
rs1003424020 325 dbSNP
rs1269711731 331 dbSNP
rs1033534269 344 dbSNP
rs183546904 359 dbSNP
rs1013448897 360 dbSNP
rs1284156636 362 dbSNP
rs1221192720 365 dbSNP
rs1359931940 383 dbSNP
rs1288391037 388 dbSNP
rs1234397424 390 dbSNP
rs1265432316 402 dbSNP
rs549302519 404 dbSNP
rs1391480289 409 dbSNP
rs1027064215 420 dbSNP
rs1430517288 434 dbSNP
rs1434564615 441 dbSNP
rs568222958 444 dbSNP
rs147336842 451 dbSNP
rs572396146 458 dbSNP
rs1459113231 464 dbSNP
rs1015514916 471 dbSNP
rs965613566 475 dbSNP
rs989320429 476 dbSNP
rs779007661 477 dbSNP
rs1212451346 482 dbSNP
rs1200724346 487 dbSNP
rs921455489 489 dbSNP
rs1229249637 493 dbSNP
rs1367513136 497 dbSNP
rs1313553100 498 dbSNP
rs1452602840 533 dbSNP
rs570703856 553 dbSNP
rs1469117455 567 dbSNP
rs539386684 568 dbSNP
rs1402063470 576 dbSNP
rs989667688 585 dbSNP
rs1459984997 589 dbSNP
rs1297153264 590 dbSNP
rs911527903 611 dbSNP
rs187890360 612 dbSNP
rs914992854 613 dbSNP
rs1181652895 614 dbSNP
rs943056756 616 dbSNP
rs975359953 617 dbSNP
rs1285569552 623 dbSNP
rs1343952419 636 dbSNP
rs1188191581 642 dbSNP
rs879020216 648 dbSNP
rs945079463 653 dbSNP
rs1042061964 656 dbSNP
rs1344371474 658 dbSNP
rs930922821 663 dbSNP
rs906167360 672 dbSNP
rs566412093 674 dbSNP
rs1315204153 679 dbSNP
rs1055036367 683 dbSNP
rs1390013972 685 dbSNP
rs1373134962 686 dbSNP
rs1309533315 688 dbSNP
rs950085910 689 dbSNP
rs895016342 716 dbSNP
rs1045869553 717 dbSNP
rs994679098 721 dbSNP
rs1027862962 722 dbSNP
rs569738158 725 dbSNP
rs888547929 727 dbSNP
rs1004676663 730 dbSNP
rs905825865 731 dbSNP
rs1488757539 732 dbSNP
rs1189610983 744 dbSNP
rs1015567001 745 dbSNP
rs1025911583 749 dbSNP
rs1249607325 758 dbSNP
rs1054897901 761 dbSNP
rs1484176474 769 dbSNP
rs759248631 776 dbSNP
rs149995907 781 dbSNP
rs376978543 781 dbSNP