miRTarBase - #MIRT577616


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pre-miRNA Information
pre-miRNA mmu-mir-324   
Genomic Coordinates chr11: 70012043 - 70012131
Synonyms Mirn324, mir-324, mmu-mir-324, Mir324
Description Mus musculus miR-324 stem-loop
Comment Kim et al. cloned 40 new miRNAs from rat E18 primary cortical neurons .
RNA Secondary Structure

Mature miRNA Information
Mature miRNA mmu-miR-324-3p
Sequence 53| CCACUGCCCCAGGUGCUGCU |72
Evidence Experimental
Experiments Cloned
Putative Targets

Gene Information
Gene Symbol Stx8   
Synonyms 0610007H08Rik, 1110002H11Rik, 4930571E13Rik, CARB
Description syntaxin 8
Transcript NM_018768   
Expression
Putative miRNA Targets on Stx8
3'UTR of Stx8
(miRNA target sites are highlighted)		 
>Stx8|NM_018768|3'UTR
   1 TAGCAATAAAGGGACCACCCGCTGTGACACCTGCCAACTACGAATGAAAGCCCAGCATCCTTTTGGTACATAACACCTGC
  81 TCTCAATAAATTTTCCACCGCTCTGGGCTCTTGGTGTACCTTGTTTGGGTAGAGAACAGAGCTGAGCAGCTCTGGAGACC
 161 TTCCTAGAGCACTGGCCCAGTTGTGTCCCCTGTCTTCTGTCAGTGATTTTGTTGGTAGTCAGAAGTCCCTCAGATGGCCA
 241 TTGTCCCACAGCTGCCAATGGATTCCAGTCACCCTCTGTGTGCTGGGCATCCTGAGGGCTGTCATATTAATAGGCAGTGT
 321 GTGACCTTGGTGGCTGCTTGTACTGCGGAAAACCACGTGCCCTTGTGCAAATGAGTGGCTGATCATGTGTCTGGGTGTCC
 401 AGATAGCAGGATCTACGTAAGGCAAGAGCCACACAGAAGACATAGCCAACAGCCTCTCTGTCAGCCACCATGTGTAATTT
 481 CCCACAAAGCTTAGATGCCCAACAGTGCTGGCTATTTCTGCTCTAAGAGTTTCTGGACCATCTTCGTATCTGGACGTGAA
 561 CCTTTTCAATTTTGCTTTGTTAATAAACGCGTCCTTCAAGATTGATGACACCTTTCTAAAACAAAATCCAGACGTGGAGG
 641 CACATGCCTTTAACCCCAGCACTTAGGAGTCAGAGGCAGTGGAGTTCAAAAAAAAAAAAACAACAACAACAAAAGACATA
 721 TTTGACACCTTTCTAAGTAGCCCACAGCCTTAGATCTTGAGGGAGGGAGCAGTCAGAGGAAAGCCTGGTTATAAAGCAGG
 801 AAGTGCTGCCTCCGTCCAGCCTCTCCACTGGCTCTGAAGCCATGTGTGTGCCAAGTGAGGGCATGCACATAAGTATTTCA
 881 GAGACAGGACTCAGAGCGAAACTGACTGCAAAAGATACCGGGTCTACAGATGGGTGCTGGGGCAGCGAGCCCTCTCTCCT
 961 CTCTCTACAGAAAGCAGGATGGGCAGTTAGCCTCGCTTTCTCATAGCAGAAAGAAGAGTTAAAGCTAATGCCAGAAGTCT
1041 TGCCGTAGCATTGGCTTCAGTGAGGAGGAGACAGGCCTGTGGTAGGTCCTGTGACTTTCCTTAAGAGAACATAATCCAAA
1121 GCCTGCGCTGGACAGAATCAGGCACCAGGAAGAAAGCCCCAGTGTCACCTAGACTGGTGCCCTTTCCTGGGACCCTGAGA
1201 CCGAGGATTCCAAGTGTTTTGTTTGACTCTGACTCATACCAGAATGCAGACAGGCAGGACAGCAATGGGGTCTCTGTGGC
1281 ACAGCAAAGGGTTTCTGGGAGCTCTCAGGCCAGCAGTGAAGTGTCCATCTCGAGAGCACATCACCTCAGCTCGAGTTCTG
1361 GCTGAACTACTTACCCTGGCCTCCCACGGGACAAGACGAAGTAACAGAAGACAAGAGAGTAAGAAACACGCTGCCGACGG
1441 GGGTTGCCATACCACTTATCAGCTCTGTGACCACAGACAGACAGGTTCCCTTTCTGTGCCAGTGGCCTCATGTACAAAAA
1521 GGTGACAATCCCCCGCTGCCCCACCTTGCCCCACCTCAGGGCTGCTGGGAGGACTGGGTGAGGTACTGAAGCACAGCAAG
1601 CCACTTGGCTCAGGTGGAAGGGGACTCTTCCTATAACACTAGTCTAAGCCGAGGTGTCCAGCAGGCTCAGGACCCTGTCT
1681 CCCACTCTTCTAAGTACACGAACTGTAGGAGCAAGCCAGGCAGGGGCAAAGTTTGCTGCTAACTTGGCCAATGATGCCCA
1761 AGTTCCTGAGGATCCCAAGGCCCTAGGAGCTGACTTAGCCAGATTGTCAGGGTCATAGTATACCAGGAGGTGGCAACTGG
1841 CAGAGGGTGTGAAGCAGGCTGTGAGGGGCGGACTGGAGGTGAAGAAGAGTGTGGGCTTGTGTCAGGGGCGTGTGATTGGG
1921 AAGACAGGAGCCTTGCTGGACTGCTGGCCAGGGCTTTAAGACACAGTGTACCCTGAGACACATTTGTCAGGGCAGGGTGG
2001 TTGCTAATGGATCATCCAATGTAAGACCAAGAATCTGTAGAGCTCCATCATCCAGTCTTGTGGGAAACCCCAAATCTGTA
2081 CAAACAGTGTCTCCTGGGAGCCCCCCACTTTGGGGCTCAGAAGCAGCAGCATTGAGAGTCTGTTTAACTTTCTCACCTCC
2161 TCTTGACTTGCTCAGCACGAAGCCCCGGCAACTCGTGGGACACTTTGAACCAGAGCCACGAAGGCCTGGCTCAGTTGCAC
2241 TGAAAGCCCTTTTCAGGAAGACACTGGCCCATGTCTGCACACAGTGGCTTCTGTTCTTCTGGCCGAATGGGCTCTAGGCC
2321 CAGTCAGGGCATTGTGTGACCCCGGACAAGTTCCTTCCCTTCTGTATACCATGGGCAGGGGAGCGCAGGAGGAAAGCTGC
2401 CTGAGAGGTTCATGGTGTGAGGACCGTGGGCACTGCAGGCAGGGAGACTCATCCCCAGGCAGTCTTCCTCAAAGATGGCT
2481 TTCCCCGCACCATCCAAAGCAGCCAGGCATGCCCAGCTGAGTGGGGTGTACCAGAGAGCCTGCTGCTTCAAAGCCCAGGG
2561 GACAGCTCCTGTAGAGTGGGGTTTGCCAGCGGTGTTTGCAAGGCCTAGTTTCCCAGTTACTATGTCAGGTCTGTAGACCA
2641 GTGACCTGCTGTGAGCGTTCTGGAACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGTGAGCATTCTGGA
2721 ACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGTGAGCATTC
2801 TGGAACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGTGAGC
2881 ATTCTGGAACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGT
2961 GAGCATTCTGGAACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTG
3041 CTGTGAGCGTTCTGGAACCAGTGACCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGTGAGCGTTCTGGAACCAGTGA
3121 CCTGCTGTGAGCATTCTGGAACCAGTGACCTGCTGTGAGCTTTCTGGAACCAGTGACCTGCTGTGAGCGTTCTAGAAGTA
3201 CACCACTCACAGAACACAGAGTGGCCAGGCAGCCAGAGCACCCCTGTCTTCAGGGACTTTGTCAATGAAAGTAAACCTTA
3281 TTAAAACAGCAGCATATGAATTGTTTAACTTAACTGATTATTAATTATATGCATCTTAAATCTGGATACCATATAAAGAA
3361 ATCCAGATACCTGGAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucGUCGUGGA-CC-------CCGUCACc 5'
            ||||||:| ||       ||||||| 
Target 5' ccCAGCACTTAGGAGTCAGAGGCAGTGg 3'
 655 - 682 158.00 -25.91
2 
miRNA  3' ucgucguggaccCCGUCACc 5'
                      ||||||| 
Target 5' gtcatattaataGGCAGTGt 3'
 301 - 320 140.00 -10.40
3 
miRNA  3' ucgUCGUGGACCCCGUCAcc 5'
             ||||    |||||||  
Target 5' gaaAGCAGGATGGGCAGTta 3'
 970 - 989 133.00 -17.30
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions C2C12
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1385343. RNA binding protein: 聽AGO2. Condition:C2C12_DM_Ago2_CLIP-Seq_myotubes ...

- Zhang X; Zuo X; Yang B; Li Z; Xue Y; Zhou et al., 2014, Cell.

Article - Zhang X; Zuo X; Yang B; Li Z; Xue Y; Zhou et al.
- Cell, 2014
MicroRNAs are well known to mediate translational repression and mRNA degradation in the cytoplasm. Various microRNAs have also been detected in membrane-compartmentalized organelles, but the functional significance has remained elusive. Here, we report that miR-1, a microRNA specifically induced during myogenesis, efficiently enters the mitochondria where it unexpectedly stimulates, rather than represses, the translation of specific mitochondrial genome-encoded transcripts. We show that this positive effect requires specific miR:mRNA base-pairing and Ago2, but not its functional partner GW182, which is excluded from the mitochondria. We provide evidence for the direct action of Ago2 in mitochondrial translation by crosslinking immunoprecipitation coupled with deep sequencing (CLIP-seq), functional rescue with mitochondria-targeted Ago2, and selective inhibition of the microRNA machinery in the cytoplasm. These findings unveil a positive function of microRNA in mitochondrial translation and suggest a highly coordinated myogenic program via miR-1-mediated translational stimulation in the mitochondria and repression in the cytoplasm.
LinkOut: [PMID: 25083871]
CLIP-seq Support 1 for dataset GSM1385343
Method / RBP HITS-CLIP /  AGO2
Cell line / Condition C2C12 / C2C12_DM_Ago2_CLIP-Seq_myotubes
Location of target site NM_018768 | 3UTR | GGAGUUCAAAAAAAAAAAAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 25083871 / GSE57596
CLIP-seq Viewer Link
351 mmu-miR-324-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT010726 March8 membrane-associated ring finger (C3HC4) 8 1 1
MIRT010727 Lix1 limb and CNS expressed 1 1 1
MIRT010728 Cplx1 complexin 1 1 1
MIRT010729 Mapk6 mitogen-activated protein kinase 6 1 1
MIRT010730 Fam19a5 family with sequence similarity 19, member A5 1 1
MIRT010731 Myo6 myosin VI 1 1
MIRT010732 Galnt7 UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7 1 1
MIRT010733 Fam195b MAPK regulated corepressor interacting protein 1 1 1
MIRT010734 Syp synaptophysin 1 1
MIRT010735 Gspt2 G1 to S phase transition 2 1 1
MIRT010736 Gpam glycerol-3-phosphate acyltransferase, mitochondrial 1 1
MIRT010737 Tln1 talin 1 1 1
MIRT010738 Gja1 gap junction protein, alpha 1 1 1
MIRT010739 Gprin3 GPRIN family member 3 1 1
MIRT010740 Cd99l2 CD99 antigen-like 2 1 1
MIRT010741 Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1 1
MIRT010742 Katnbl1 katanin p80 subunit B like 1 1 1
MIRT010743 Clock circadian locomotor output cycles kaput 1 1
MIRT010744 Garnl3 GTPase activating RANGAP domain-like 3 1 1
MIRT010745 Lsamp limbic system-associated membrane protein 1 1
MIRT010746 Zkscan8 zinc finger with KRAB and SCAN domains 8 1 1
MIRT010747 Lipa lysosomal acid lipase A 1 1
MIRT010748 Acot7 acyl-CoA thioesterase 7 1 1
MIRT010749 Stx17 syntaxin 17 1 1
MIRT010750 Smad3 SMAD family member 3 1 1
MIRT010751 Fbxo18 F-box protein 18 1 1
MIRT010752 Fam171b family with sequence similarity 171, member B 1 1
MIRT010753 Kif1b kinesin family member 1B 1 1
MIRT010754 Slc17a6 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 1 1
MIRT010755 Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 1 1
MIRT010756 Vat1 vesicle amine transport 1 1 1
MIRT010757 Eif1a eukaryotic translation initiation factor 1A 1 1
MIRT010758 Heg1 heart development protein with EGF-like domains 1 1 1
MIRT010759 Itm2c integral membrane protein 2C 1 1
MIRT010760 Nr2c2 nuclear receptor subfamily 2, group C, member 2 1 1
MIRT010761 Tor1aip2 torsin A interacting protein 2 1 1
MIRT010762 Rmnd5a required for meiotic nuclear division 5 homolog A 1 1
MIRT010763 Cav2 caveolin 2 1 1
MIRT010764 March6 membrane-associated ring finger (C3HC4) 6 2 2
MIRT010765 Zfp516 zinc finger protein 516 1 1
MIRT010766 4931428F04Rik RIKEN cDNA 4931428F04 gene 1 1
MIRT010767 Cln8 ceroid-lipofuscinosis, neuronal 8 1 1
MIRT010768 Ccdc50 coiled-coil domain containing 50 1 1
MIRT010769 Gpc1 glypican 1 1 1
MIRT010770 Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 1 1
MIRT010771 Rap2c RAP2C, member of RAS oncogene family 1 1
MIRT010772 Ttc3 tetratricopeptide repeat domain 3 1 1
MIRT010773 Rabgap1l RAB GTPase activating protein 1-like 1 1
MIRT010774 Shc4 SHC (Src homology 2 domain containing) family, member 4 1 1
MIRT010775 Canx calnexin 1 1
MIRT010776 Hyal1 hyaluronoglucosaminidase 1 1 1
MIRT010777 Acss1 acyl-CoA synthetase short-chain family member 1 1 1
MIRT010778 Zfp521 zinc finger protein 521 1 1
MIRT010779 Sytl2 synaptotagmin-like 2 1 1
MIRT010780 Tpra1 transmembrane protein, adipocyte asscociated 1 1 1
MIRT010781 Lnpep leucyl/cystinyl aminopeptidase 1 1
MIRT010782 Fem1b feminization 1 homolog b (C. elegans) 1 1
MIRT010783 Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 1 1
MIRT010784 Smad4 SMAD family member 4 1 1
MIRT010785 Cadm3 cell adhesion molecule 3 1 1
MIRT010786 Tm9sf4 transmembrane 9 superfamily protein member 4 1 1
MIRT010787 Tmem131 transmembrane protein 131 1 1
MIRT010788 Zeb2 zinc finger E-box binding homeobox 2 1 1
MIRT010789 Zfp414 zinc finger protein 414 1 1
MIRT010790 Pygb brain glycogen phosphorylase 1 1
MIRT010791 Gnptab N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 1 1
MIRT010792 Prrt1 proline-rich transmembrane protein 1 1 1
MIRT010793 Jam2 junction adhesion molecule 2 1 1
MIRT010794 Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) 1 1
MIRT010795 Utrn utrophin 1 1
MIRT010796 H2-D1 histocompatibility 2, D region locus 1 1 1
MIRT010797 Lrrc4 leucine rich repeat containing 4 1 1
MIRT010798 Epb4.1l2 erythrocyte membrane protein band 4.1 like 2 1 1
MIRT010799 Patl1 protein associated with topoisomerase II homolog 1 (yeast) 1 1
MIRT010800 Ppig peptidyl-prolyl isomerase G (cyclophilin G) 1 1
MIRT010801 Evl Ena-vasodilator stimulated phosphoprotein 1 1
MIRT010802 Ralgapb Ral GTPase activating protein, beta subunit (non-catalytic) 1 1
MIRT010803 Clcn4-2 chloride channel, voltage-sensitive 4 1 1
MIRT010804 Anxa5 annexin A5 1 1
MIRT010805 Akap9 A kinase (PRKA) anchor protein (yotiao) 9 1 1
MIRT010806 Hdac6 histone deacetylase 6 1 1
MIRT010807 Nuak1 NUAK family, SNF1-like kinase, 1 1 1
MIRT010808 Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1 1
MIRT010809 Impad1 inositol monophosphatase domain containing 1 1 1
MIRT010810 Ncan neurocan 1 1
MIRT010811 Usp6nl USP6 N-terminal like 1 1
MIRT010812 2700081O15Rik RIKEN cDNA 2700081O15 gene 1 1
MIRT010813 Slc24a2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 1 1
MIRT010814 Mbip MAP3K12 binding inhibitory protein 1 1 1
MIRT010815 Bag4 BCL2-associated athanogene 4 1 1
MIRT010816 Eps15 epidermal growth factor receptor pathway substrate 15 1 1
MIRT010817 Gnao1 guanine nucleotide binding protein, alpha O 1 1
MIRT010818 Ncam1 neural cell adhesion molecule 1 1 1
MIRT010819 Bola2 bolA-like 2 (E. coli) 1 1
MIRT010820 Lin7c lin-7 homolog C (C. elegans) 1 1
MIRT010821 Whsc1l1 nuclear receptor binding SET domain protein 3 1 1
MIRT010822 Enpp4 ectonucleotide pyrophosphatase/phosphodiesterase 4 1 1
MIRT010823 Slc4a8 solute carrier family 4 (anion exchanger), member 8 1 1
MIRT010824 Pptc7 PTC7 protein phosphatase homolog 1 1
MIRT010825 Fbxl18 F-box and leucine-rich repeat protein 18 1 1
MIRT010826 Mtmr4 myotubularin related protein 4 1 1
MIRT010827 Chd4 chromodomain helicase DNA binding protein 4 1 1
MIRT010828 Intu inturned planar cell polarity protein 1 1
MIRT010829 Faf2 Fas associated factor family member 2 1 1
MIRT010830 Vezt vezatin, adherens junctions transmembrane protein 1 1
MIRT010831 Tacc1 transforming, acidic coiled-coil containing protein 1 1 1
MIRT010832 Zzef1 zinc finger, ZZ-type with EF hand domain 1 1 1
MIRT010833 Frmd5 FERM domain containing 5 1 1
MIRT010834 Ocln occludin 1 1
MIRT010835 Dpysl2 dihydropyrimidinase-like 2 1 1
MIRT010836 Baz2a bromodomain adjacent to zinc finger domain, 2A 1 1
MIRT010837 Syt1 synaptotagmin I 1 1
MIRT010838 Reep1 receptor accessory protein 1 1 1
MIRT010839 Ankrd46 ankyrin repeat domain 46 1 1
MIRT010840 Narg2 interactor of little elongation complex ELL subunit 2 1 1
MIRT010841 C230081A13Rik pseudopodium-enriched atypical kinase 1 1 1
MIRT010842 Kif5c kinesin family member 5C 1 1
MIRT010843 Pip4k2c phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1 1
MIRT010844 Ugt8a UDP galactosyltransferase 8A 1 1
MIRT010845 Klf9 Kruppel-like factor 9 1 1
MIRT010846 Ppapdc1b phospholipid phosphatase 5 1 1
MIRT010847 Iqsec2 IQ motif and Sec7 domain 2 1 1
MIRT010848 Dvl2 dishevelled segment polarity protein 2 1 1
MIRT010849 Tmx4 thioredoxin-related transmembrane protein 4 1 1
MIRT010850 Slc31a1 solute carrier family 31, member 1 1 1
MIRT010851 Oxsr1 oxidative-stress responsive 1 1 1
MIRT010852 Snx30 sorting nexin family member 30 1 1
MIRT010853 Klhl23 kelch-like 23 1 1
MIRT010854 Zmat4 zinc finger, matrin type 4 1 1
MIRT010855 Ap2a2 adaptor-related protein complex 2, alpha 2 subunit 1 1
MIRT010856 Cbx5 chromobox 5 1 1
MIRT010857 Slc25a46 solute carrier family 25, member 46 1 1
MIRT010858 Ryk receptor-like tyrosine kinase 1 1
MIRT010859 Lmbrd1 LMBR1 domain containing 1 1 1
MIRT010860 Spred2 sprouty-related, EVH1 domain containing 2 1 1
MIRT010861 Frs2 fibroblast growth factor receptor substrate 2 1 1
MIRT010862 Acvr1b activin A receptor, type 1B 1 1
MIRT010863 Snn stannin 1 1
MIRT010864 Dgcr2 DiGeorge syndrome critical region gene 2 1 1
MIRT010865 Col12a1 collagen, type XII, alpha 1 1 1
MIRT010866 Fam104a family with sequence similarity 104, member A 1 1
MIRT010867 Cbfb core binding factor beta 1 1
MIRT010868 Sdc2 syndecan 2 1 1
MIRT010869 Cdc27 cell division cycle 27 1 1
MIRT010870 G3bp2 GTPase activating protein (SH3 domain) binding protein 2 1 1
MIRT010871 Riok3 RIO kinase 3 1 1
MIRT010872 Osbpl9 oxysterol binding protein-like 9 1 1
MIRT010873 Prkcb protein kinase C, beta 1 1
MIRT010874 Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 1 1
MIRT010875 Padi2 peptidyl arginine deiminase, type II 1 1
MIRT010876 Cd200 CD200 antigen 1 1
MIRT010877 Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 1 1
MIRT010878 Pan3 PAN3 poly(A) specific ribonuclease subunit 1 1
MIRT010879 Pex19 peroxisomal biogenesis factor 19 1 1
MIRT010880 Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1 1
MIRT010881 Cfl2 cofilin 2, muscle 1 1
MIRT010882 Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A 1 1
MIRT010883 Dos calcium channel, voltage-dependent, beta subunit associated regulatory protein 1 1
MIRT010884 Zmym4 zinc finger, MYM-type 4 1 1
MIRT010885 Rabl3 RAB, member RAS oncogene family-like 3 1 1
MIRT010886 Laptm4a lysosomal-associated protein transmembrane 4A 1 1
MIRT010887 Mmp24 matrix metallopeptidase 24 1 1
MIRT010888 Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 1
MIRT010889 Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 1 1
MIRT010890 Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 1 1
MIRT010891 Pard6g par-6 family cell polarity regulator gamma 1 1
MIRT010892 Igbp1 immunoglobulin (CD79A) binding protein 1 1 1
MIRT010893 Arpp21 cyclic AMP-regulated phosphoprotein, 21 1 1
MIRT010894 Scn3b sodium channel, voltage-gated, type III, beta 1 1
MIRT010895 Nmb neuromedin B 1 1
MIRT010896 Rab5b RAB5B, member RAS oncogene family 1 1
MIRT010897 Tgfbr2 transforming growth factor, beta receptor II 1 1
MIRT010898 Trps1 transcriptional repressor GATA binding 1 1 1
MIRT010899 Snhg11 small nucleolar RNA host gene 11 1 1
MIRT010900 Rock2 Rho-associated coiled-coil containing protein kinase 2 1 1
MIRT010901 Ccdc25 coiled-coil domain containing 25 1 1
MIRT010902 Ash1l ash1 (absent, small, or homeotic)-like (Drosophila) 1 1
MIRT010903 Ralgds ral guanine nucleotide dissociation stimulator 1 1
MIRT010904 Nlgn2 neuroligin 2 1 1
MIRT010905 Ankrd12 ankyrin repeat domain 12 1 1
MIRT010906 Gtf2i general transcription factor II I 1 1
MIRT010907 Lrrc58 leucine rich repeat containing 58 1 1
MIRT010908 Macf1 microtubule-actin crosslinking factor 1 1 1
MIRT010909 Alkbh5 alkB homolog 5, RNA demethylase 1 1
MIRT010910 Cldn25 claudin domain containing 1 1 1
MIRT010911 Nfxl1 nuclear transcription factor, X-box binding-like 1 1 1
MIRT010912 Ttpal tocopherol (alpha) transfer protein-like 1 1
MIRT010913 Antxr1 anthrax toxin receptor 1 1 1
MIRT010914 Hook1 hook microtubule tethering protein 1 1 1
MIRT010915 Fam135a family with sequence similarity 135, member A 1 1
MIRT010916 Slc22a23 solute carrier family 22, member 23 1 1
MIRT010917 Asxl2 additional sex combs like 2 (Drosophila) 1 1
MIRT010918 Caln1 calneuron 1 1 1
MIRT010919 Gpm6b glycoprotein m6b 1 1
MIRT010920 Igf1r insulin-like growth factor I receptor 1 1
MIRT010921 Rhov ras homolog family member V 1 1
MIRT010922 Tmem135 transmembrane protein 135 1 1
MIRT010923 Astn1 astrotactin 1 1 1
MIRT010924 Etv3 ets variant 3 1 1
MIRT010925 Crat carnitine acetyltransferase 1 1
MIRT010926 Pim3 proviral integration site 3 1 1
MIRT010927 Klhl32 kelch-like 32 1 1
MIRT010928 Ppp6c protein phosphatase 6, catalytic subunit 1 1
MIRT010929 Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 1 1
MIRT010930 Kitl kit ligand 1 1
MIRT010931 Scn4b sodium channel, type IV, beta 1 1
MIRT010932 Pcmtd2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 1 1
MIRT010933 Pcnx pecanex homolog (Drosophila) 1 1
MIRT010934 Tcf4 transcription factor 4 1 1
MIRT010935 Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 1 1
MIRT010936 Rc3h2 ring finger and CCCH-type zinc finger domains 2 1 1
MIRT010937 Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 1 1
MIRT010938 Zfp652 zinc finger protein 652 1 1
MIRT010939 Mecp2 methyl CpG binding protein 2 1 1
MIRT010940 Ankrd28 ankyrin repeat domain 28 1 1
MIRT010941 Wnk1 WNK lysine deficient protein kinase 1 1 1
MIRT010942 Usp46 ubiquitin specific peptidase 46 1 1
MIRT010943 Csrnp2 cysteine-serine-rich nuclear protein 2 1 1
MIRT010944 Ablim1 actin-binding LIM protein 1 1 1
MIRT010945 Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 1 1
MIRT010946 Slc12a2 solute carrier family 12, member 2 1 1
MIRT010947 Rab6b RAB6B, member RAS oncogene family 1 1
MIRT010948 Mettl16 methyltransferase like 16 1 1
MIRT010949 Arl6ip5 ADP-ribosylation factor-like 6 interacting protein 5 1 1
MIRT010950 Usp7 ubiquitin specific peptidase 7 1 1
MIRT010951 Dag1 dystroglycan 1 1 1
MIRT010952 Maml1 mastermind like 1 (Drosophila) 1 1
MIRT010953 Tanc2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 1 1
MIRT010954 Rab6a RAB6A, member RAS oncogene family 1 1
MIRT010955 Kmt2a lysine (K)-specific methyltransferase 2A 1 1
MIRT010956 Ric3 RIC3 acetylcholine receptor chaperone 1 1
MIRT010957 Pdzd2 PDZ domain containing 2 1 1
MIRT010958 Ccdc127 coiled-coil domain containing 127 1 1
MIRT010959 4933426M11Rik sushi domain containing 6 1 1
MIRT010960 Cnot6 CCR4-NOT transcription complex, subunit 6 1 1
MIRT010961 Scamp1 secretory carrier membrane protein 1 1 1
MIRT010962 Rassf4 Ras association (RalGDS/AF-6) domain family member 4 1 1
MIRT010963 Rgl1 ral guanine nucleotide dissociation stimulator,-like 1 1 1
MIRT010964 Slc35d1 solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 1 1
MIRT010965 Fbxw7 F-box and WD-40 domain protein 7 1 1
MIRT010966 Dmtf1 cyclin D binding myb-like transcription factor 1 1 1
MIRT010967 Il1r1 interleukin 1 receptor, type I 1 1
MIRT010968 Zfyve26 zinc finger, FYVE domain containing 26 1 1
MIRT010969 Gpatch8 G patch domain containing 8 1 1
MIRT010970 Mapk14 mitogen-activated protein kinase 14 1 1
MIRT010971 Mkrn2 makorin, ring finger protein, 2 1 1
MIRT010972 Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 1 1
MIRT010973 Syt11 synaptotagmin XI 1 1
MIRT010974 Myt1 myelin transcription factor 1 1 1
MIRT010975 Bmpr1a bone morphogenetic protein receptor, type 1A 1 1
MIRT010976 Tmod2 tropomodulin 2 1 1
MIRT010977 Tenm4 teneurin transmembrane protein 4 1 1
MIRT010978 Ccnjl cyclin J-like 1 1
MIRT010979 Nme1 NME/NM23 nucleoside diphosphate kinase 1 1 1
MIRT010980 Cpeb2 cytoplasmic polyadenylation element binding protein 2 1 1
MIRT010981 Gigyf2 GRB10 interacting GYF protein 2 1 1
MIRT010982 Lrrc57 leucine rich repeat containing 57 1 1
MIRT010983 Fndc5 fibronectin type III domain containing 5 1 1
MIRT010984 Ept1 selenoprotein I 1 1
MIRT010985 Slc12a7 solute carrier family 12, member 7 1 1
MIRT010986 Rbm39 RNA binding motif protein 39 1 1
MIRT010987 Esyt2 extended synaptotagmin-like protein 2 1 1
MIRT010988 Zmiz1 zinc finger, MIZ-type containing 1 1 1
MIRT010989 Rap1gap Rap1 GTPase-activating protein 1 1
MIRT010990 Gnb1 guanine nucleotide binding protein (G protein), beta 1 1 1
MIRT010991 Gfap glial fibrillary acidic protein 1 1
MIRT010992 Zeb1 zinc finger E-box binding homeobox 1 1 1
MIRT010993 Clip1 CAP-GLY domain containing linker protein 1 1 1
MIRT010994 Ngfrap1 brain expressed X-linked 3 1 1
MIRT010995 Hs3st5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 1 1
MIRT010996 Drd2 dopamine receptor D2 1 1
MIRT010997 Ttyh3 tweety family member 3 1 1
MIRT010998 Lpgat1 lysophosphatidylglycerol acyltransferase 1 1 1
MIRT010999 Mtmr6 myotubularin related protein 6 1 1
MIRT011000 Nedd4 neural precursor cell expressed, developmentally down-regulated 4 1 1
MIRT011001 Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 1 1
MIRT011002 Nudcd3 NudC domain containing 3 1 1
MIRT011003 Mid2 midline 2 1 1
MIRT011004 Ank2 ankyrin 2, brain 1 1
MIRT011005 Ednra endothelin receptor type A 1 1
MIRT011006 Myo18a myosin XVIIIA 1 1
MIRT011007 Mtch1 mitochondrial carrier 1 1 1
MIRT011008 Ppm1f protein phosphatase 1F (PP2C domain containing) 1 1
MIRT011009 Cpm carboxypeptidase M 1 1
MIRT011010 Adam10 a disintegrin and metallopeptidase domain 10 1 1
MIRT011011 L1cam L1 cell adhesion molecule 1 1
MIRT011012 Lrp3 low density lipoprotein receptor-related protein 3 1 1
MIRT011013 Jazf1 JAZF zinc finger 1 1 1
MIRT011014 Hpcal4 hippocalcin-like 4 1 1
MIRT011015 Sfmbt1 Scm-like with four mbt domains 1 1 1
MIRT011016 Rit1 Ras-like without CAAX 1 1 1
MIRT011017 Fam73a mitoguardin 1 1 1
MIRT011018 Rnf44 ring finger protein 44 1 1
MIRT011019 Tmem109 transmembrane protein 109 1 1
MIRT011020 Dkk3 dickkopf WNT signaling pathway inhibitor 3 1 1
MIRT011021 Rogdi rogdi homolog 1 1
MIRT011022 Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) 1 1
MIRT011023 Papd7 PAP associated domain containing 7 1 1
MIRT011024 Reep5 receptor accessory protein 5 1 1
MIRT011025 Gfod1 glucose-fructose oxidoreductase domain containing 1 1 1
MIRT011026 Ulk1 unc-51 like kinase 1 1 1
MIRT011027 Tsc1 tuberous sclerosis 1 1 1
MIRT011028 Adcy5 adenylate cyclase 5 1 1
MIRT011029 2810407C02Rik selenoprotein T 1 1
MIRT011030 Stx16 syntaxin 16 1 1
MIRT011031 Pacs2 phosphofurin acidic cluster sorting protein 2 1 1
MIRT011032 Slc43a2 solute carrier family 43, member 2 1 1
MIRT011033 Atrn attractin 1 1
MIRT011034 Cnksr3 Cnksr family member 3 1 1
MIRT011035 Ctnnb1 catenin (cadherin associated protein), beta 1 1 1
MIRT011036 Zfp106 zinc finger protein 106 1 1
MIRT011037 Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 1 1
MIRT011038 Cacna2d3 calcium channel, voltage-dependent, alpha2/delta subunit 3 1 1
MIRT011039 Prkdc protein kinase, DNA activated, catalytic polypeptide 1 1
MIRT011040 Gatsl2 GATS protein-like 2 1 1
MIRT011041 Rsbn1l round spermatid basic protein 1-like 1 1
MIRT011042 Map2k1 mitogen-activated protein kinase kinase 1 1 1
MIRT011043 Ap2b1 adaptor-related protein complex 2, beta 1 subunit 1 1
MIRT011044 Nrsn1 neurensin 1 1 1
MIRT011045 Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1 1
MIRT011046 Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1 1
MIRT011047 Smg7 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) 1 1
MIRT011048 Zfp148 zinc finger protein 148 1 1
MIRT011049 Zfp592 zinc finger protein 592 1 1
MIRT011050 Gda guanine deaminase 1 1
MIRT011051 Wasf2 WAS protein family, member 2 1 1
MIRT011052 Nploc4 NPL4 homolog, ubiquitin recognition factor 1 1
MIRT011053 Rab3c RAB3C, member RAS oncogene family 1 1
MIRT011054 Mdn1 midasin AAA ATPase 1 1 1
MIRT011055 Zzz3 zinc finger, ZZ domain containing 3 2 8
MIRT011056 Osbpl8 oxysterol binding protein-like 8 1 1
MIRT011057 Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein 1 1
MIRT011058 Pds5b PDS5 cohesin associated factor B 1 1
MIRT011059 Nup50 nucleoporin 50 1 1
MIRT011060 Wdr85 diphthamine biosynethesis 7 1 1
MIRT011061 Hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit 1 1
MIRT011062 Stag1 stromal antigen 1 1 1
MIRT011063 Skil SKI-like 1 1
MIRT011064 Nos1 nitric oxide synthase 1, neuronal 1 1
MIRT011065 Psd3 pleckstrin and Sec7 domain containing 3 1 1
MIRT011066 Abl2 v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) 1 1
MIRT011067 Wwtr1 WW domain containing transcription regulator 1 1 1
MIRT011068 Klhdc10 kelch domain containing 10 1 1
MIRT577616 Stx8 syntaxin 8 2 2
MIRT580733 Srrm4 serine/arginine repetitive matrix 4 2 2
MIRT591397 Cog7 component of oligomeric golgi complex 7 2 6
MIRT596081 Tfb2m transcription factor B2, mitochondrial 2 2
MIRT597622 Psmb11 proteasome (prosome, macropain) subunit, beta type, 11 2 2
MIRT598278 Mdp1 magnesium-dependent phosphatase 1 2 2
MIRT600595 Nfib nuclear factor I/B 2 2
MIRT601450 Tpmt thiopurine methyltransferase 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-324 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 down-regulated
miR-324-3p Longevinex NULL NULL Quantitative real-time PCR ischemia/reperfusion [I/R] rat model 21203465 2011 down-regulated
miR-324-3p Resveratrol NULL 445154 Quantitative real-time PCR ischemia/reperfusion [I/R] rat model 21203465 2011 down-regulated
miR-324-3p Gemcitabine approved 60750 Northern blot Mz-ChA-1 human cholangiocarcinoma cell lines 16762633 2006 down-regulated
miR-324-3p FdUMP[10] NULL 25244711 Microarray NCI-60 cell-line 21159603 2011 up-regulated
miR-324-3p Floxuridine (FdU) approved 5790 Microarray NCI-60 cell-line 21159603 2011 up-regulated
miR-324-3p Irinotecan approved 60838 Microarray NCI-60 cell-line 21159603 2011 up-regulated
miR-324-3p Topotecan approved 60700 Microarray NCI-60 cell-line 21159603 2011 up-regulated
miR-324-3p Dexamethasone approved 5743 Quantitative real-time PCR human colorectal adenocarcinoma Caco-2 21796641 2011 down-regulated
miR-324-3p Mitoxantrone approved 4212 Quantitative real-time PCR human colorectal adenocarcinoma Caco-2 21796641 2011 down-regulated
miR-324-3p Paclitaxel approved 36314 Quantitative real-time PCR human colorectal adenocarcinoma Caco-2 21796641 2011 down-regulated
miR-324-3p Vinblastine approved 13342 Quantitative real-time PCR Human breast cancer MCF-7 cells 21796641 2011 down-regulated

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