miRTarBase - #MIRT585960


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pre-miRNA Information
pre-miRNA mmu-mir-466e   
Genomic Coordinates chr2: 10479088 - 10479171
Synonyms mmu-mir-466e, Mir466e
Description Mus musculus miR-466e stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA mmu-miR-466e-5p
Sequence 12| GAUGUGUGUGUACAUGUACAUA |33
Evidence Experimental
Experiments Cloned
Putative Targets

Gene Information
Gene Symbol Sike1   
Synonyms 2810005O12Rik, 5730470L24Rik, AI450236, AI839862, Sike, Sikeb
Description suppressor of IKBKE 1
Transcript NM_025679   
Expression
Putative miRNA Targets on Sike1
3'UTR of Sike1
(miRNA target sites are highlighted)		 
>Sike1|NM_025679|3'UTR
   1 CTGGACTTCCGAAGGCTGGCTACAGCTTGCCCGTCAGAGCGAGAAGCCGTGCCCTCCTCTCCTGCCGTGTCCAAGAGTCC
  81 TGCCGCAGACTTGACTTAGTGTTGGGTAGAGGTATGGGGTGGCAGTTTAGAATTGCCACTTGGTATTCATTGTCCACTAA
 161 CTAGTTTGGGGTGTACTAGTGAAACTAGACAAGTCCCCCATTGCTGGGACAGAGATGACATTTGTCACTCTAGTCCGGAA
 241 TCTCTATAAACTGTTACCTGCAGTTCAATGTTGTTTTTCACAGCTTGGAAACACTGAACACTTTTATTATAAGCCAGGAT
 321 TTTATTTTATATAGGATTATAAAAATTCCTTCTAAGAGTTTTTCAAAGATTTAACTTTTTAAAAATACATATTTGGTGTA
 401 AACCTAGATTTTTTTTTTCTTCCACTTGTAAAAGTAGCATGACTTCAAAGAAGCAGATTGGCAGAGTCTCTGAGTGACGT
 481 CGCTCATCCATGGGGTTTGATCCTCTCCGGTGCTAGGAGTTGGCACTTTGTGGTCAGGTGTCTTTGCTCTTAATTTGAGA
 561 GAATCTATTAGTCCCCAGGAAATACGCTTGAAAACAAGTAAGCCGGGTTCGCGTTGCTCCTCCTCCTCCTCAAGGATCCA
 641 CAGTCATTCAGAGAGTGCTGAGGAACTTGGGCCTGCCCCATCATGCACAGGGAGCTATTAGATGTACATGACTGTACATG
 721 TACATTGGACTTAAATGCCAAAAATAGCTTTTATTTATTTGACCAAGTAGTTTTCCATTCTGTCTGCCTAAGGAGTCTTC
 801 GGCTTAGGTAGTTGCCTTGTATGAGACATACACATACACACACACACACACACACACACACACACACACACACATACCTC
 881 ACTCACAGGTTCCTAGCTCCTAGGCACTTTCATGGACACACAGCTGTGCTGTGCTGTGCTGTGCAGAGCAGCACCACTGG
 961 GATGGTTTAGACCGGCATCAGTACTTTGCTGTCTTTCCATCTGCTGGGTTTTCTCATGGAAGCATTTTATTACTCACAGA
1041 AAGTTACCACATTCCTGATGCCATGCATTCAGGCAATCAAGAACAACCTGAGATTCTAATAGCTCCCTGTCAGTTCCTTC
1121 TCATCTTGGTTTGCTCATATGTCAGGTTTATAAATAATTCCTTTTGCACTGTTTGCCCAGATGGACTTTGGTTTTTGTTC
1201 CCATGTTAACTTTCACTCCAGCTGCTCCCCTTGATGTTTCCCCTAAGGGCCCCAAGTGTGTACTCCACAAACCCATTCAG
1281 GGGTGGGTTCCTTTACCACTTGTCAGCTGTCACAGCAGGTCCCATCACAGTGAGAGCATTATCAGTCAGTCTATTTCAGC
1361 AGTGAGCATGGTGTCCCTTTCTTTATCTGCCTTCTGTTCCCGTAGCACTCACTACAAAGGTCTTTGCATCTAGCTTTCAG
1441 AGGAATCTCTCCATTGCAGTCCTGAGGGTAGAGCAAGCTTTCGGTGCCCTGTGTCGTATAAATTCTGCCTGGTGTTAGTG
1521 CTGTGAAGGCATTGCAGAGCTAGCACATTGAATGGAGAAAGAATGTTTCACACTTGTGTGAAGATGCTAATATCTCTTGC
1601 AATGGGTGGAAGTATTTAGTGTATAAAATTTTAGTATGAAATTATATTAACTAATAAAAACCTTTTTGAGAAGATTTGCT
1681 CATTTTACTGAGAAATGAGTCTAAGAAGTTGAGCTGGAAAAAAAAAGGAAGTTTAGCTGAGCAGTGGCGATGTACACCTG
1761 CAATCCCAGCACTTGGAAGGCAGAGGCACATCTCTTGAATTCGAGGACATGCAGGTTTACCTAGTGAGTCCCAGGAGACT
1841 ACACAGGGAGACCCTGTCTTGAAAAAAGCAAAAAGAAGTATAGGAGATTTTTTTCACATATTCACATACATAGCAACCAT
1921 GGCAAGTGTTCATGACATAGATGTCATAAGCAGCTTGCAATTATTCAATATATTCAGCAGTATAAACCTTTGAAAAGCAC
2001 ATTAACAACCTATTCATTGCAGAAGTCCTGAATGTATAATTTACCACTGAAGTCTATTTCCATGTTTCTTAAAATGCACC
2081 TAATGAAATAGAAATTTATGGATGG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' auacaUGUACAUGUGUGUGUAg 5'
               |||   |||||||||| 
Target 5' cacacACACACACACACACATa 3'
 855 - 876 161.00 -14.40
2 
miRNA  3' auACAUGUACAUGUGUGUGUAg 5'
            ||||:: | |||:|||||| 
Target 5' ctTGTATGAG-ACATACACATa 3'
 816 - 836 155.00 -15.40
3 
miRNA  3' auacaUGUACAUGUGUGUGUAg 5'
               |||| | ||||:|||| 
Target 5' ttttcACATATTCACATACATa 3'
 1891 - 1912 153.00 -13.10
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions mESCs
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM622570. RNA binding protein: AGO2. Condition:WT1A HITS-CLIP data was present in GSM622571. RNA binding protein: AGO2. Condition:WT1B ...

- Leung AK; Young AG; Bhutkar A; Zheng GX; et al., 2011, Nature structural & molecular biology.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' auacAUGUACAUGUGUGUGUag 5'
              ||||  ||||||||||  
Target 5' ---aUACACAUACACACACAca 3'
 		1 - 19
Article - Leung AK; Young AG; Bhutkar A; Zheng GX; et al.
- Nature structural & molecular biology, 2011
MicroRNAs (miRNAs) are 19-22-nucleotide noncoding RNAs that post-transcriptionally regulate mRNA targets. We have identified endogenous miRNA binding sites in mouse embryonic stem cells (mESCs), by performing photo-cross-linking immunoprecipitation using antibodies to Argonaute (Ago2) followed by deep sequencing of RNAs (CLIP-seq). We also performed CLIP-seq in Dicer(-)/(-) mESCs that lack mature miRNAs, allowing us to define whether the association of Ago2 with the identified sites was miRNA dependent. A significantly enriched motif, GCACUU, was identified only in wild-type mESCs in 3' untranslated and coding regions. This motif matches the seed of a miRNA family that constitutes ~68% of the mESC miRNA population. Unexpectedly, a G-rich motif was enriched in sequences cross-linked to Ago2 in both the presence and absence of miRNAs. Expression analysis and reporter assays confirmed that the seed-related motif confers miRNA-directed regulation on host mRNAs and that the G-rich motif can modulate this regulation.
LinkOut: [PMID: 21258322]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Liver
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in ERR266281. RNA binding protein: AGO2. Condition:A_Liver partial hapatectomy 48h HITS-CLIP data was present in ERR266292. RNA binding protein: AGO2. Condition:B_Liver partial hapatectomy 48h HITS-CLIP data was present in ERR266300. RNA binding protein: AGO2. Condition:B_Untreated ...

- Schug J; McKenna LB; Walton G; Hand N; et al., 2013, BMC genomics.

Article - Schug J; McKenna LB; Walton G; Hand N; et al.
- BMC genomics, 2013
BACKGROUND: Validation of physiologic miRNA targets has been met with significant challenges. We employed HITS-CLIP to identify which miRNAs participate in liver regeneration, and to identify their target mRNAs. RESULTS: miRNA recruitment to the RISC is highly dynamic, changing more than five-fold for several miRNAs. miRNA recruitment to the RISC did not correlate with changes in overall miRNA expression for these dynamically recruited miRNAs, emphasizing the necessity to determine miRNA recruitment to the RISC in order to fully assess the impact of miRNA regulation. We incorporated RNA-seq quantification of total mRNA to identify expression-weighted Ago footprints, and developed a microRNA regulatory element (MRE) prediction algorithm that represents a greater than 20-fold refinement over computational methods alone. These high confidence MREs were used to generate candidate 'competing endogenous RNA' (ceRNA) networks. CONCLUSION: HITS-CLIP analysis provide novel insights into global miRNA:mRNA relationships in the regenerating liver.
LinkOut: [PMID: 23597149]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions C2C12
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1385342. RNA binding protein: 聽AGO2. Condition:C2C12_GM_Ago2_CLIP-Seq_myoblast ...

- Zhang X; Zuo X; Yang B; Li Z; Xue Y; Zhou et al., 2014, Cell.

Article - Zhang X; Zuo X; Yang B; Li Z; Xue Y; Zhou et al.
- Cell, 2014
MicroRNAs are well known to mediate translational repression and mRNA degradation in the cytoplasm. Various microRNAs have also been detected in membrane-compartmentalized organelles, but the functional significance has remained elusive. Here, we report that miR-1, a microRNA specifically induced during myogenesis, efficiently enters the mitochondria where it unexpectedly stimulates, rather than represses, the translation of specific mitochondrial genome-encoded transcripts. We show that this positive effect requires specific miR:mRNA base-pairing and Ago2, but not its functional partner GW182, which is excluded from the mitochondria. We provide evidence for the direct action of Ago2 in mitochondrial translation by crosslinking immunoprecipitation coupled with deep sequencing (CLIP-seq), functional rescue with mitochondria-targeted Ago2, and selective inhibition of the microRNA machinery in the cytoplasm. These findings unveil a positive function of microRNA in mitochondrial translation and suggest a highly coordinated myogenic program via miR-1-mediated translational stimulation in the mitochondria and repression in the cytoplasm.
LinkOut: [PMID: 25083871]
CLIP-seq Support 1 for dataset GSM622570
Method / RBP HITS-CLIP / AGO2
Cell line / Condition mESCs / WT1A
Location of target site NM_025679 | 3UTR | AUACACAUACACACACACACAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21258322 / GSE25310
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM622571
Method / RBP HITS-CLIP / AGO2
Cell line / Condition mESCs / WT1B
Location of target site NM_025679 | 3UTR | AUACACAUACACACACACACAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21258322 / GSE25310
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset ERR266281
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Liver / A_Liver partial hapatectomy 48h
Location of target site NM_025679 | 3UTR | UACACAUACACACACACACACACACACACACACACA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23597149 / E-MTAB-1612
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset ERR266292
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Liver / B_Liver partial hapatectomy 48h
Location of target site NM_025679 | 3UTR | UACACAUACACACACACACACACACACACACACACA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23597149 / E-MTAB-1612
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset ERR266300
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Liver / B_Untreated
Location of target site NM_025679 | 3UTR | UACACAUACACACACACACACACACACACAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23597149 / E-MTAB-1612
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1385342
Method / RBP HITS-CLIP /  AGO2
Cell line / Condition C2C12 / C2C12_GM_Ago2_CLIP-Seq_myoblast
Location of target site NM_025679 | 3UTR | ACAUACACAUACACACACACACACACACACA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 25083871 / GSE57596
CLIP-seq Viewer Link
145 mmu-miR-466e-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT410978 Ado 2-aminoethanethiol (cysteamine) dioxygenase 2 2
MIRT417624 Lifr leukemia inhibitory factor receptor 2 2
MIRT432330 Igf2 insulin-like growth factor 2 2 4
MIRT577332 Zfp157 zinc finger protein 157 2 2
MIRT577683 Slc39a14 solute carrier family 39 (zinc transporter), member 14 2 6
MIRT577854 Rassf5 Ras association (RalGDS/AF-6) domain family member 5 2 2
MIRT578123 Nqo2 N-ribosyldihydronicotinamide quinone reductase 2 2 2
MIRT578174 Neu1 neuraminidase 1 2 2
MIRT578293 Mavs mitochondrial antiviral signaling protein 2 2
MIRT578540 Htr1f 5-hydroxytryptamine (serotonin) receptor 1F 2 2
MIRT578635 Gtf2h2 general transcription factor II H, polypeptide 2 2 2
MIRT578659 Gramd1c GRAM domain containing 1C 2 2
MIRT578883 Fam107a family with sequence similarity 107, member A 2 6
MIRT578911 Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT579075 Cox15 cytochrome c oxidase assembly protein 15 2 4
MIRT579095 Cnih3 cornichon family AMPA receptor auxiliary protein 3 2 4
MIRT579133 Chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) 2 2
MIRT579301 BC021785 major facilitator superfamily domain containing 4B5 2 2
MIRT579361 Aplnr apelin receptor 2 2
MIRT580013 Whsc1l1 nuclear receptor binding SET domain protein 3 2 4
MIRT580126 Ubn2 ubinuclein 2 2 2
MIRT580259 Trim12c tripartite motif-containing 12C 2 2
MIRT580358 Tmem26 transmembrane protein 26 2 2
MIRT580397 Tmem170b transmembrane protein 170B 2 2
MIRT580836 Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 2 2
MIRT581003 Six4 sine oculis-related homeobox 4 2 2
MIRT581112 Sept3 septin 3 2 2
MIRT581333 Rgs8 regulator of G-protein signaling 8 2 2
MIRT581426 Rasal2 RAS protein activator like 2 2 2
MIRT581434 Rasa2 RAS p21 protein activator 2 2 2
MIRT581473 Rabgap1 RAB GTPase activating protein 1 2 2
MIRT581601 Prkcd protein kinase C, delta 2 2
MIRT581808 Plag1 pleiomorphic adenoma gene 1 2 2
MIRT581914 Pgm3 phosphoglucomutase 3 2 2
MIRT582069 Onecut2 one cut domain, family member 2 2 2
MIRT582600 Lrrc40 leucine rich repeat containing 40 2 2
MIRT582752 Klf8 Kruppel-like factor 8 2 2
MIRT583022 Htt huntingtin 2 2
MIRT583260 Gnb4 guanine nucleotide binding protein (G protein), beta 4 2 4
MIRT583313 Gfod1 glucose-fructose oxidoreductase domain containing 1 2 2
MIRT583618 Fam46a family with sequence similarity 46, member A 2 2
MIRT583813 Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha 2 2
MIRT583908 Drp2 dystrophin related protein 2 2 2
MIRT584442 Ccdc85a coiled-coil domain containing 85A 2 2
MIRT584656 B4galt6 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 2 2
MIRT584859 Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 2 2
MIRT584912 Akap10 A kinase (PRKA) anchor protein 10 2 2
MIRT585294 Zfp26 zinc finger protein 26 2 2
MIRT585429 Wars2 tryptophanyl tRNA synthetase 2 (mitochondrial) 2 2
MIRT585487 Txlnb taxilin beta 2 2
MIRT585694 Tbc1d24 TBC1 domain family, member 24 2 2
MIRT585739 Steap2 six transmembrane epithelial antigen of prostate 2 2 2
MIRT585878 Slc22a8 solute carrier family 22 (organic anion transporter), member 8 2 8
MIRT585907 Slc17a5 solute carrier family 17 (anion/sugar transporter), member 5 2 2
MIRT585960 Sike1 suppressor of IKBKE 1 2 6
MIRT586177 Ptprr protein tyrosine phosphatase, receptor type, R 2 2
MIRT586589 Mrgpre MAS-related GPR, member E 2 2
MIRT586806 Ints8 integrator complex subunit 8 2 2
MIRT586919 Heatr2 dynein, axonemal assembly factor 5 2 4
MIRT586945 Gstt3 glutathione S-transferase, theta 3 2 2
MIRT587123 Gfpt1 glutamine fructose-6-phosphate transaminase 1 2 2
MIRT587151 Gcnt4 glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase) 2 2
MIRT587239 Nxpe3 neurexophilin and PC-esterase domain family, member 3 1 1
MIRT587482 D630045J12Rik RIKEN cDNA D630045J12 gene 2 8
MIRT587489 D630003M21Rik RIKEN cDNA D630003M21 gene 2 2
MIRT587602 Cml2 N-acetyltransferase 8 (GCN5-related) family member 2 2 2
MIRT587664 Cdk7 cyclin-dependent kinase 7 2 2
MIRT587741 Cd28 CD28 antigen 2 2
MIRT587752 Cd200r1 CD200 receptor 1 2 2
MIRT587775 Ccpg1 cell cycle progression 1 2 2
MIRT587839 Casp8 caspase 8 2 4
MIRT587959 Asah2 N-acylsphingosine amidohydrolase 2 2 2
MIRT588288 1700019G17Rik N-acetyltransferase 8 (GCN5-related) family member 4 2 2
MIRT588355 Zfp518b zinc finger protein 518B 2 2
MIRT588392 Zeb2 zinc finger E-box binding homeobox 2 2 2
MIRT588548 Uhrf1bp1l UHRF1 (ICBP90) binding protein 1-like 2 2
MIRT588604 Tsc22d3 TSC22 domain family, member 3 2 2
MIRT588726 Tbx22 T-box 22 2 2
MIRT588954 Scn2a1 sodium channel, voltage-gated, type II, alpha 2 2
MIRT589780 Insig2 insulin induced gene 2 2 4
MIRT589840 Hif1an hypoxia-inducible factor 1, alpha subunit inhibitor 2 2
MIRT589863 Hecw1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 2 2
MIRT589975 Gabpb2 GA repeat binding protein, beta 2 2 2
MIRT590188 Ell2 elongation factor RNA polymerase II 2 2 2
MIRT590360 Clca2 chloride channel accessory 3A2 2 2
MIRT590488 Calcoco1 calcium binding and coiled coil domain 1 2 2
MIRT590659 Apba1 amyloid beta (A4) precursor protein binding, family A, member 1 2 2
MIRT590843 Wdr46 WD repeat domain 46 2 2
MIRT590859 Vps33b vacuolar protein sorting 33B 2 4
MIRT590920 Tacr2 tachykinin receptor 2 2 2
MIRT590936 Supt7l suppressor of Ty 7-like 2 2
MIRT591004 Sh2d2a SH2 domain containing 2A 2 2
MIRT591018 Scd3 stearoyl-coenzyme A desaturase 3 2 2
MIRT591037 Rfx3 regulatory factor X, 3 (influences HLA class II expression) 2 2
MIRT591045 Rassf2 Ras association (RalGDS/AF-6) domain family member 2 2 2
MIRT591136 Nsun3 NOL1/NOP2/Sun domain family member 3 2 2
MIRT591225 Ly96 lymphocyte antigen 96 2 2
MIRT591308 Il18r1 interleukin 18 receptor 1 2 2
MIRT591349 Flrt1 fibronectin leucine rich transmembrane protein 1 2 2
MIRT591363 Egfl6 EGF-like-domain, multiple 6 2 2
MIRT591410 Cer1 cerberus 1, DAN family BMP antagonist 2 2
MIRT591443 Bcl2 B cell leukemia/lymphoma 2 2 2
MIRT591521 Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 2 2
MIRT591577 Zfhx3 zinc finger homeobox 3 2 4
MIRT591597 Xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 2 2
MIRT591614 Vps37a vacuolar protein sorting 37A 2 2
MIRT591708 Rpusd2 RNA pseudouridylate synthase domain containing 2 2 2
MIRT591720 Rorb RAR-related orphan receptor beta 2 2
MIRT591740 Rab9b RAB9B, member RAS oncogene family 2 4
MIRT591815 Mocs1 molybdenum cofactor synthesis 1 2 2
MIRT591838 Lin7a lin-7 homolog A (C. elegans) 2 2
MIRT591850 Iglon5 IgLON family member 5 2 2
MIRT591897 Fbrs fibrosin 2 2
MIRT591978 Ap1ar adaptor-related protein complex 1 associated regulatory protein 2 2
MIRT592164 Oxtr oxytocin receptor 2 2
MIRT592241 LOC100048884 major urinary protein 18 2 2
MIRT592285 Gatc glutamyl-tRNA(Gln) amidotransferase, subunit C 2 2
MIRT592450 Ski ski sarcoma viral oncogene homolog (avian) 2 2
MIRT592466 Runx1 runt related transcription factor 1 2 2
MIRT592683 Has2 hyaluronan synthase 2 2 2
MIRT592831 Asb7 ankyrin repeat and SOCS box-containing 7 2 2
MIRT592853 Akap2 A kinase (PRKA) anchor protein 2 2 2
MIRT593348 Tmco1 transmembrane and coiled-coil domains 1 2 2
MIRT593391 Adra1b adrenergic receptor, alpha 1b 2 2
MIRT593402 Znrf3 zinc and ring finger 3 2 2
MIRT593411 Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 2 2
MIRT593503 Enpp4 ectonucleotide pyrophosphatase/phosphodiesterase 4 2 2
MIRT594179 Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor 2 2
MIRT594723 Zfp931 zinc finger protein 931 2 2
MIRT594918 Gm14326 predicted gene 14326 2 2
MIRT594954 Fblim1 filamin binding LIM protein 1 2 2
MIRT594996 Tmem245 transmembrane protein 245 1 1
MIRT595717 Calcr calcitonin receptor 2 2
MIRT601211 Arhgef9 CDC42 guanine nucleotide exchange factor (GEF) 9 2 2
MIRT604988 Fsd1l fibronectin type III and SPRY domain containing 1-like 2 2
MIRT605314 Zfp92 zinc finger protein 92 2 2
MIRT605458 St18 suppression of tumorigenicity 18 2 2
MIRT605538 Pstpip2 proline-serine-threonine phosphatase-interacting protein 2 2 2
MIRT605601 Nbeal1 neurobeachin like 1 2 2
MIRT605769 Epas1 endothelial PAS domain protein 1 2 2
MIRT605937 Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 2 2
MIRT605986 Mylk4 myosin light chain kinase family, member 4 2 2
MIRT606188 Slc5a8 solute carrier family 5 (iodide transporter), member 8 2 2
MIRT606238 Rab3c RAB3C, member RAS oncogene family 2 2
MIRT606736 Tacr1 tachykinin receptor 1 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-466e-5p Tert-butyl hydroperoxide (t-BHP) NULL 6410 Microarray mouse auditory cells 20510889 2010 up-regulated

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