miRTarBase - #MIRT593155


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pre-miRNA Information
pre-miRNA mmu-mir-1906-1   
Genomic Coordinates chr12: 109544541 - 109544620
Description Mus musculus miR-1906-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA mmu-mir-1906-2   
Genomic Coordinates chrX: 88759474 - 88759553
Synonyms mmu-mir-1906, Mir1906
Description Mus musculus miR-1906-2 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA mmu-miR-1906
Sequence 48| UGCAGCAGCCUGAGGCAGGGCU |69
Evidence Experimental
Experiments Microarray
Putative Targets

Gene Information
Gene Symbol Itsn1   
Synonyms AA517634, AA545208, AI316805, AI839402, AI848451, Ehsh1, Ese1, Itsn, Sh3p17
Description intersectin 1 (SH3 domain protein 1A)
Transcript NM_010587   
Other Transcripts NM_001110275 , NM_001110276   
Expression
Putative miRNA Targets on Itsn1
3'UTR of Itsn1
(miRNA target sites are highlighted)		 
>Itsn1|NM_010587|3'UTR
   1 CAGCCCTGCGATGATCGTAGATGACTTCCTCCTCAAGGCCCCGTGCGGGCGTGCTGTCTGGTGGTCAGCCTCAGAGCAAC
  81 GGGGATGAAGCAAAGACGAAGCCCCTCGAGGCTGCTAGGAGTCGTTCTCGACAATCCTGCCCTTCAAACCATGTCTCATT
 161 TTATGAATCCAAATTCTCTTTTCCTTTGCTCTCCCTATGGTCTCATCATGGCTTCTAGAGTCTCTGAAATCTGTGACCTT
 241 TAACTAGGTTCCATTGGGAGCCTGGCTCCTTCCCTGGGCTGGAGGTGTGGGTCTGATTCCTATAAAATAGATTTATAAAC
 321 ACAGTGACTGTATTTTGGAGAACTGTGTAGGCCTCCTATTTCTCTCCTCTACCAGCCCTTCGTAGACTACTTGGCCTATA
 401 ATATCGTGTGTGTGTGTCCAATTATGACGGAATTGTGGCTTCGGAGCCCAGCCCTCCCTGGGAGATGGGGCCCTAGATTG
 481 AATGGCTCTGGAGCAGACACCAACGTACTTAACCCTCTGGAGAGCTGTCGCTTAGAAGACACTCCCATGTGTCGTTAGAG
 561 CTGTACCATTCCCCTCTAGACTTCCTTAGTGCCCATCAGTGGAAACACGGTGGTGGCATGCTACAGGGTGATTCCGTTCC
 641 GATTCTGGGTGAGCTTGGAGGATCCTCCAAAAGCTCATTATCTGCAAGGTTCTGTCCTGATGAGTTAGGTCCTGCCGTGG
 721 GTCACTGCGGGTCACTGGGATGACCTTGGCTTGGTTATTGTCAGAGCATCCTCTTTGGGCTTGGAGACCCTGGAATGTTT
 801 CATGAGAAGTTCTGTCTGGAGACCAGTCCTGTCTGAGCCCATTCTGTGCTTGAAAGACTTGTGAGAAGTAACAACAACAA
 881 TCCTTAGTGGTCACCGCACCCCCAAACCCCACCACACCAGGAAGTCATGCCTTAGATGGATGAAGTTCAAAAAAGAAAGA
 961 ATTCAAGATAGAATAGGTAGTGTGGAGAAACGCTAAGAAAATCCATTACTGGTTTGAGGGAAAGACCTTTGGGAACCCGT
1041 GAGCCCCACATGTGGGGTGGGAAAATGGGCGATGCTCCTGGGCATACAACAACCTCTTAGTCATAGGAACACACGCACTT
1121 TTTGCGAGAATCAGGAGTGTATGACCATAGGCCAGGCTTTTTTGTCTGAGTTCTTTGGGTTTTCTCTCCCTTAAATGCTA
1201 AAAGATAGGCTGGTTATCTAGATAACTTGATTTGCTAGTGAGAAGTGCAGGCTGTTTTGGTCCCTCGTTTGCATCTCCAG
1281 TCTGTGGTCATGGCCTGGCCTTTGCATGTCTCAGGCTCCTGGGCTCAGGCTTTCCTGTGTTGGGTGGCCTGGCCTTTGCA
1361 TGTCTCAGGCTCCTGGGCTCAGGCTCTCCTGTGTTGGGTGGTGTTCCTTTTTATGGTAGGTTCTCAGATTTTAACTAGGT
1441 TTCTAGAAGTACTTTGTAAATGGTAGTGTCTCGGTGACAGAATAGCCACTCTGCTGAAATCTGAATGCTCCATGTGACCC
1521 CAGAAGGTCCCTCTCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTCAAGTGATTTCTCAAAACGTGTATGGGGCAAAGG
1601 ACAACAGTTTACATTTCATACTTCCAAGAAGCACTTAGAGTTTATTTATTGAAGATAGTGTTGACTTTTGTATCAAGAAC
1681 AACAGACACACCTATTTTTTGAAACAAGCCAATAAACTCTTCAGGTAGCAGCTTTCAGCTGAACATGAGGTAGACTTTAA
1761 CTTCGAGCATGCGTTGGCTTACCACTTTCCCAGCAGAAAACACTATCAAAACACTACACATTCATGTTTCTGTTGTTGTT
1841 AAGAAACTGTTTTAAATGATACCTATAACTAGATCTGTGACCCATGGTTTCTTGGTTCTGGAACCAGGGGGGCTTTGTTC
1921 GGCATGTTGATAAAGGACATGCTCCCATACTGTGAAACACAGACATTCTGTGTGCAAATGGCCAGTATAGGGTCACCATT
2001 ACAATCCCTTCCCCTCCCCCTTCCAAGTTGAACATGAACATGATGTTGAACATCAGTGTTCCTGTAGGAAGGATGAGGCA
2081 TGCATGGTGACCCCATAGGTTCTGGGTTACCTACTCATAGCAAGCACCCCATGATTGTAGTATGTGAATGCAGTCTGTGA
2161 GTCTTTCCCCCAGGTGACCCTACTAGACACCCCTGGGTTGTCCTGAGGGGTGACAGATCTGGATTGGTGTCATTTGTTGT
2241 GATTAATTGTATTTCTGGATGAGCTGGGCTGACCCTCAGACCCAGCTGTGACTCCTGGTTTCTGTTGAGATGGAGTCCTA
2321 TTGTGACCCATGGGTGACACACAGAGTCTCAAACCTTGATTCTCTCCTCCTTGACTCTACTTTTTTGACCAGCTAGCCTT
2401 CAGTTCCTACAAATGGTAGGTCCTTGCCAACGAGGAATCTGAGGCTCAGATGTCTGCTTTGTAAATGCTTGCCCAGGCTG
2481 CACCACCTGGCACCTTGATGCCAGCTGTTCAGATACCCCCTGAAGGCATCCCTCTTCTATGGGCCACACTGCCAGTACCT
2561 CCCACACTCTGACCTCCTCTCACTCAGGAAGGCACTTTCCTGGAGCCTGGCTATGCTCTGACCCTCAGTCACCCCTGAGA
2641 ATTATCCCGAGAGCTCTGAGGACAGAAGCCCCTGACTGGGCTTCCTTCATGGGCCACTTGATCCAAAGGGTCAGTCCTTG
2721 TCTCTGGGGAAGCGTCCATGTTTTGTCACCCAGCAGATGGATGGATAGCTTTATCTCTTGGGACCAGATTTGCTGTGTCC
2801 ACAAGAGTTTGGAGACATATGTCAATCATTAAGGTCCAGATCTGCCCTCGATGGAACAGAGAGCCTTCTAGATGAGAGTC
2881 AGCAGGAATGCTGGAGAAACTGGGCAAGGGTGCTGGGTTCAATTTTGTAATGATATGTCTCTGTCATTGGACAGCAAATA
2961 AGAAACTTCTCTCCCTAAAGAACCTTTCTTCCTTATTTTCAGACAGGACCTGACTCCATAGCCCAAGATGTCCTTGAACT
3041 TAGGGTCCTCCTGTCTCAGCCTCCCGTGTGCTGGAATTTCAAGTGTGTCCCGCTGGGCTCAGCTGTCTTCATTTTTATAA
3121 AAGGTGGATCAATGGGCCGCTCATACTGCCTGTTATCTTCACTCAGTGCCAACGTGTGTTCTAGACGTGTGTCACGAGGT
3201 CACAGGCGTCTGGAAAGGGTGATCGCAGGTTGGTCTTCCAGGGTGGGACAGCAGCTACCTCCCCAGGAGCTGCTGGGCAG
3281 GAGAGAGCTGGGCAGGAGAGAGCTGGTGACCATATACAGTCCAGGGTGTCCTAGAATCCATTAATCAAGGACACATGGAC
3361 GGGCCCCTCTGGCTTTCATTTGACAGGTGGAGAACCTGAGCCAGCTGAGACCGCAGGGAGGATTTGCACCCCCAAGGGCT
3441 TTGTTTCTAGCTGTTCGGACCTGGCCTGATTCCTAGGAAGAAGCCAAACCTCTGATGGATTCTTTTCCTCTTTTAGACCC
3521 TGTCAGAATCCAGATGCACGAGAGTTAGAGACAGTTCCTCCTCCTCTTCCTCCTCCCCCTCCTCCCTCTCCTCTTCCTCC
3601 TCCCCCTCCTCCCTCTCCTCCTCTTCCTCCTCTCCCTCCCCCTCCTCCTCCTCTTCCCTGGATTGGCCCCATGGGCCCAA
3681 ATTCTTGTTTTTCTTTGTTTCCCCCTTATTCTCCAAAGACACATTGAAGCTGACATTTCAGGGAATGCCTTATTGGGCAG
3761 GCCTACAGAGGCTGGCTTGTATGAGTGGTGGGAACCTCCTCAGAAGAGCCCAATCTTGCTGACTAGTAATTGACAGTAAG
3841 GAGTCCCCAACATGGGTCCTAAGATGCCACCCCCTCCTCCCCTGTATCTCCCCGCTCCTCCCCTGCACAGTCTCCTTTAA
3921 AGGGGGGTCAGCACCTGACCTTTTCCCAACTCCATTGCTTGCCTACCTGCCAAGGGACCCTGTTCTGCAGGGACGTGGGG
4001 GTGTGAGGGTCACCGGGCCAAGGTAATGCAGGAGAAAAAAGGAGGGAAGGAAAAAGGAAGAGAGAAAGAAGGAAGGATGG
4081 ATGTAAGGATAGAAGGGATGGAGGAAGGAGGGAGACAGGGCAGGTGGTCAAAGAGAACGTTAAAGAGGCTTCCTCGCAGG
4161 TTATGAAGGTAAGGGCTCACTCAGTGCCACGTACTCCCCGTGGGGGTTTAGGGGACCGCATCTCTGGAGAAGAGACTCGC
4241 AAACTGAAGATGGGACTTACCCCTGCCCTCCTTGTCATGGAGACTTAGACCTCTAGTGTAGCAGCCCCTAGAACCATCAC
4321 GGCTTCCTTTCTTTTTTATTTCTTTTTTAAAGATTTATTTATTATACTTAAAAAACAGACACACCAGAAGAGGGTGTCAA
4401 ATCTCATTACGGATGGTTGTGAGCCACCATGTGGTTGCTGGGATTTGAACTCAGGATCTTCAGAAGAGCAGTCAGTGCTC
4481 TTAACCACTGAGCCATCTCTCCAGCCCCCACCATCACGGCTTTCTGAGTGGCAAATTCCCAGAGGCCCTTGGGCATAGCA
4561 TTCTCTTTTGAATGACTCCTATTAATGAACATTGTCCTTTGAAGGGCTATTCAAGGAAATAATGAAGACTTCTTGTTAGT
4641 TTGGACTTGCAATAAATAACTGGCTGGTTGCCACAGGGACTCCTCTTTCCAGTTCCCTGTTTCCTGATACCTAGAAAGTA
4721 GCTGAGCTAGAGGAAGAGAAAGTCCCGGAGACCGTTTCCTCACAGGACATTGCACGAGGTCCCTGTGGTCCCAAGGATCC
4801 ACTAATGTGTATAATGACTTCGTGTCTGTAAGCGCCAGGAAAGGTTCTGTCCTTGAGAAGCACAGGAAAATACAACCCGT
4881 GAGAAAGATGGCCAGGATCTCAGGCTCTCTAAGTTGAGAGCATTGAAACTCCTATGTCAGCACCCTGGGCAGACTGCAGT
4961 CAGGAACAGCAACACAGTGAGCAATGCTGACAGGATGCTGTTCCTTCAGGGGGGCTCTATCCTGTCCAGGCCGCCTGTTG
5041 GGGGCTGGGAGGCAGAGAAGGGACCTCCTTTGTGGCTTTTAAGCCAACTTGTAGATCTAATTTTAAGTCACTTTAATAAC
5121 ATAAAATTCCTGCTCAGTGGCTGGGTAGATCGCTGACAAAGTGCTAGCCCGGCAAACCTGAGGCCCTGAGTTTGATCCCC
5201 AGCCCTTTCGTAAAGAAACCAGATTCAGCATGCGTAGCTGTAGTACCAGAGCTGGGGATGTGGAGACAGGGGGATTGTTG
5281 GACTTGTTTCTTGGTGCCGTGGCTCACAGGGGTTGGGACTGGGGATGTCTTGAAGGATAAGGTACAGAAAACTCAGTACG
5361 GAAACATTAGTGTTTATCTCCACCAAACAACTAACTCAGTTCTACTCAGACCTAACTAGTTCCTTTAGTAAAAGGAGCTA
5441 ATAGTTTATATTTTGGCAAATAATTCTCCTAGCACTGTGTGTGGCTGTCCTATTTCAGGGTGAATTGCCCCTACGCTGTG
5521 TCAGGTCCTATGCTATATTTTAATCGGATCTGTTCTGTTTTCTGGAGCAGCCTAGAGTCTCGCTGTTATTACAGTGATGA
5601 GTATTTTAGTGTTCGAAGTCCACCGAGGAGAGTTTCATTCAGAAGCGGGCTTATTCCGTCAGCCTTCAGATTGCCCAGCG
5681 TCCCTCCGGGATTTCTGGGGAGCTGGCCAGTGACCAAGGCTCCTTTTTACGCTGTGGAAATTCCTCCCTTCTTCTTTTAG
5761 AACCATCGTACCCGTATCCTGTGCGAGAGCTGCGCCTGTGGTTTTCTGCCTCCCCGGCTATACTCTTTTGTCTTTCTTGT
5841 CTTATCTCCTGTTCTCGGTGAAAACAAGAGTGGGGACCTTAGACAAATAGGAGCCAAAGGCAGCGTGGTGGCTTGTGTGG
5921 CCATTTCCGCACTGTGGGGCTCTTCCTACCTAGATGGTTCTATTGGCAGGGTCAAGGTGCTGGCGCCCCCTGCTGCATCC
6001 CAGCAGCATTGCTCTTGTGGAACTTGCTAGTGAGAGGGGTGGGGGTAGGGTCAGGGCTAGAACCCGACTGTAGTGCTCCC
6081 CGACTCTCCCAGCTGAGCCGTGAGCAAAGAAGGAAGGTGTGAGTGAACCCAGCGCTGGGCACCTACTGAAATGGCGTTCC
6161 TGCCTGCTGGGGTGGACAGAGACCCTCCTCAGCTTCCCTGCCTTTTCTGTGCCTTCAGAGGGGAATGTTGCAATTCAGTT
6241 CTCCACAGAAAAGGACTGGCTTCCTGAAGTAGGCCTCTGTCCCTGCGAGACAGGGTAGCCCTACTTGGTAGGATAGCAGG
6321 GTGTCTACCTGAAGACTTCGACTTTGGACGTTTTAAGTGGCAAATGGTTTGATGCAGCCCTTGGATGCCCGGAGTGTGTC
6401 TGTGAGTGAGTGTGTATGTGTGTACCAAGCATTGGGGGATGGCTGTGTGTCCCACTGAAGGAGACAGGAGATGTTTTGCT
6481 CTACCCTTCCCCAAGCTGCATTCAGGACCAGCTGGTAATGTGTGGACCAAGTGCAAAAATAAAAATGGCCTCCTCCTTGC
6561 TCCAAATGATTAGGGATTTCAGCAGGGGCAGCAGAGAACTGAGCTGAGTTTGGGCCCTGCTGTTTGGAGGGGCTCCAACA
6641 CCCTGGGGCTGGCCTTGACTACACTGTGAATGGAGCAGGGAGGGCCTTGTTATGTCTTTCTTCTTTGGAAAGGTCTCCCT
6721 GGCAGGCTGCGCGGAGCTGAGATGGAAACACATCGTCCCTTCTCCCTCTCTCCCCCCTCCCTCCCTTGTTTTCTTTTCCT
6801 TTCCTTGCAGTGCTAATTATCAAAGCCAGGGCCTCGTGCATTCTTAGAAAGTGAGGTGCTTTTCAAAACTCTACTCTTTT
6881 ATCTCTTAAAAGTACAAACAGTGCAGAATAATTACAGCGCCCGAACCCCCGGCTAACACCTGGAAGCGCCCTGGATGGAC
6961 GGGGAATGGTCAACATAGGTTGATGGTTTCTCAAGTCTCCGTCCAGGGTGTGTCTCTGGATATCAAGTGGGGCCTTTGAG
7041 TCTTCAAAGTTGAATTTTCTGCTTTGAAATGAAACCTTTCCCTATTCAAGGGTTGGTCTCCCGGTTTCTGGTGTCACAGA
7121 GGAGATTCTAAACTACTTTAATGGAGAAGAGCCTAGAAGAGCACAGGGTCCCTGTCTGACATCGAGAGGTCCTTTGTTCC
7201 TTTAGATACTGCTTTCTGGAGAGAGAGTGGGCGGAGCCAGATGCCTCTCTGCCCTAGAGGCCAAGTGTCTGAGAGTTTAC
7281 TCCTGGGAGGCAGGGCTCTCACGGGATAGATCCTCCATGTGTCTTTGGGTGTTCGCAAAGAAGAAAGGCTCTGCTGTGTG
7361 TGTAACCTCTGCATTCTGGAAGCCCACAGCTCTGGGGAGGCCAGAAGTTAGGAAGCCGCTCCTCAAAGGTGTGTGTGTGT
7441 GTGTGTGTGTGTGTGTGTGTTGCTTTGTTGTGCAGCCTGTGTTGTGTTGGATGCTCCAAGCCCTTTGAGGCTCTGTTTGC
7521 CGTTTGCAGATGTGGACCCATGTCCACACATGCAGAGCAATAATCTTTCTCGAGTTTCCCGATTCCACTCCTGTAATCCC
7601 AGCGCTCCAGAGATAGAAGCAGGAGAATCAGGAGTTTAAGGCCAGTCTGGGCTACGTGAGACCCTCTTTCAAAACTAGAA
7681 ACACAGAAACTGAGAAGGGAAAACCCACAGAAGGCTCACCTGCCTCAGCTTTAAATCACCTTAAATGGGTCATGATCCCT
7761 AGAGGGACCTGACCACTACTCTGCCAGCATCCATTTTAATGAGTGAAGATTTTGGATACCCTTCATCAATTAACATTCTC
7841 TAAGCGTTACTTGCTGAATATTGCTGTCAGATCGTTCTCTCAAATGATGCTCAATGGTAAGACATGCATTTAACTGAGCA
7921 TTTGTTGTCAATGGAGCTGAGAGGTCAGCCTCAGCTCTGGTCCTTGGCAGCCCACAAGCTAAAGTCTCCTTGCCCCTCCG
8001 TCTGCCGCGGTGCACACAGGGGCGCAGGCTACCATTCCCCTGTGCTGTACTGTCTTCGCTCTTCTGCTCTGCAACATTCC
8081 ACACGTCGATGGTGAACATAGGTGAACATATCTGTACAGAGGCGAGAAACCTCCGCCAAATGTCCTGTGTCTGACAGTCA
8161 GCTCACAGCTCCTGGGTTTCTGTATTTTGTGCATTTTCCAACAAAGGAAAAAGACGGAAATCCACTACATAATGTGAAAA
8241 GATTGTGTTCTGTATGTGGTTCGTCAGGAAATCTTTGCTGTATGTTTTTGGCAATGATGATTATATGTGTATACAGTATG
8321 TAAGAGGCTATGCTGTTCAATGTTGCATAAACTTAACAGTCTCTAGTCTGAATATCTAACTTGTTATTGTAAAATGTGAT
8401 TTCTCATCGAGAGATTATTTTTCTGTATGTATATGAGAGTATTTTAGGAATCTAACTTAAGTGCATAAACTATAGAAGAA
8481 ACTTAAAATCATATCCCAGGAGTAGAAATGCGTGATCAGGTCACTTGGGTTCAACCCATCTAAATTTTATTAAAAAACAA
8561 ATCCAAAGTG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucggGACGGAGUCCGACGACGu 5'
              ||| | |   ||||||| 
Target 5' ggtgCTGGCGCCCCCTGCTGCa 3'
 5976 - 5997 150.00 -19.40
2 
miRNA  3' ucgGGACGGAGUC--CGACGACgu 5'
             ||| || |||  |||||||  
Target 5' ctaCCT-CCCCAGGAGCTGCTGgg 3'
 3255 - 3277 144.00 -21.20
3 
miRNA  3' ucGGGAC--GGAGUCCGACGACGu 5'
            ||:||  |||| | |||| || 
Target 5' ctCCTTGCCCCTCCGTCTGCCGCg 3'
 7986 - 8009 138.00 -19.90
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Liver
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in ERR266292. RNA binding protein: AGO2. Condition:B_Liver partial hapatectomy 48h ...

- Schug J; McKenna LB; Walton G; Hand N; et al., 2013, BMC genomics.

Article - Schug J; McKenna LB; Walton G; Hand N; et al.
- BMC genomics, 2013
BACKGROUND: Validation of physiologic miRNA targets has been met with significant challenges. We employed HITS-CLIP to identify which miRNAs participate in liver regeneration, and to identify their target mRNAs. RESULTS: miRNA recruitment to the RISC is highly dynamic, changing more than five-fold for several miRNAs. miRNA recruitment to the RISC did not correlate with changes in overall miRNA expression for these dynamically recruited miRNAs, emphasizing the necessity to determine miRNA recruitment to the RISC in order to fully assess the impact of miRNA regulation. We incorporated RNA-seq quantification of total mRNA to identify expression-weighted Ago footprints, and developed a microRNA regulatory element (MRE) prediction algorithm that represents a greater than 20-fold refinement over computational methods alone. These high confidence MREs were used to generate candidate 'competing endogenous RNA' (ceRNA) networks. CONCLUSION: HITS-CLIP analysis provide novel insights into global miRNA:mRNA relationships in the regenerating liver.
LinkOut: [PMID: 23597149]
CLIP-seq Support 1 for dataset GSM4751759
Method / RBP HITS-CLIP / AGO
Cell line / Condition adipose tissue / RNA sequencing of iBAT 4
Location of target site NM_010587 | 3UTR | CCCUGCUGCAUCCCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE142677
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset ERR266292
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Liver / B_Liver partial hapatectomy 48h
Location of target site NM_001110276 | 3UTR | UGUGACUCUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGACGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23597149 / E-MTAB-1612
CLIP-seq Viewer Link
27 mmu-miR-1906 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT578439 Irgq immunity-related GTPase family, Q 2 10
MIRT578971 Dhdh dihydrodiol dehydrogenase (dimeric) 2 4
MIRT580446 Tln2 talin 2 2 2
MIRT582494 Mbtps2 membrane-bound transcription factor peptidase, site 2 2 2
MIRT587588 Cox15 cytochrome c oxidase assembly protein 15 2 2
MIRT589524 Mtf1 metal response element binding transcription factor 1 2 2
MIRT591281 Klc1 kinesin light chain 1 2 4
MIRT591935 Ddx19b DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b 2 2
MIRT592084 Sorcs2 sortilin-related VPS10 domain containing receptor 2 2 2
MIRT592206 Mapkap1 mitogen-activated protein kinase associated protein 1 2 4
MIRT592349 Armcx6 armadillo repeat containing, X-linked 6 2 4
MIRT592351 Angel1 angel homolog 1 2 2
MIRT592365 4930444A02Rik protein-O-mannose kinase 2 2
MIRT592427 Spsb4 splA/ryanodine receptor domain and SOCS box containing 4 2 2
MIRT592671 Itgav integrin alpha V 2 2
MIRT592712 Fbxo21 F-box protein 21 2 4
MIRT593155 Itsn1 intersectin 1 (SH3 domain protein 1A) 2 2
MIRT593662 Spen SPEN homolog, transcriptional regulator (Drosophila) 2 2
MIRT593976 Cdc14b CDC14 cell division cycle 14B 2 2
MIRT597931 Pacsin2 protein kinase C and casein kinase substrate in neurons 2 2 2
MIRT597949 Opa1 OPA1, mitochondrial dynamin like GTPase 2 2
MIRT598550 Isoc1 isochorismatase domain containing 1 2 2
MIRT599017 Fgd4 FYVE, RhoGEF and PH domain containing 4 2 2
MIRT600307 Tacc1 transforming, acidic coiled-coil containing protein 1 2 2
MIRT603647 Otop1 otopetrin 1 2 2
MIRT605000 Fam168b family with sequence similarity 168, member B 2 2
MIRT606275 Oxsm 3-oxoacyl-ACP synthase, mitochondrial 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-1 Anthocyanin NULL 145858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Caffeic acid NULL 689043 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Catechin approved 9064 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Ferulic acid NULL 445858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Hesperidin NULL 10621 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Quercetin NULL 5280343 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 up-regulated
miR-1 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Quantitative real-time PCR myocardial differentiation of mouse ES cells 19521018 2009 down-regulated
miR-1 Sulfonyl-hydrazone-1 (SHZ) NULL NULL Quantitative real-time PCR Murine broblast-derived Induced pluripotent stem cells 21445862 2011 up-regulated
miR-1 Cocaine NULL 446220 Next-generation sequencing ventral striatum 21708909 2011 up-regulated
miR-1 Atorvastatin approved 60823 Quantitative real-time PCR Cardiomyocyte 23860036 2013 down-regualted
miR-1 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-1 Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 Palmitic acid approved 985 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miR-1 Essential amino acids (EAA) NULL NULL Quantitative real-time PCR skeletal muscle of young adults 19828686 2009 up-regulated
miR-1 Hydrogen peroxide (H2O2) NULL 784 Quantitative real-time PCR Human umbilical vein endothelial cells 21527937 2011 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Microarray apoptosis-resistant breast cancer cells 21971930 2011 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-1 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-1 Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR cardia 22889704 2012 up-regulated
miR-1 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-1 Quinidine approved 441074 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 up-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 down-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR post-infarction rat cardiomyocytes 21220930 2011 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miR-1 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 up-regulated

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