miRTarBase - #MIRT607723


—
pre-miRNA Information
pre-miRNA hsa-mir-4532   
Genomic Coordinates chr20: 57895394 - 57895444
Description Homo sapiens miR-4532 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4532
Sequence 6| CCCCGGGGAGCCCGGCG |22
Evidence Experimental
Experiments Illumina
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol LIMS1   
Synonyms PINCH, PINCH-1, PINCH1
Description LIM zinc finger domain containing 1
Transcript NM_004987   
Expression
Putative miRNA Targets on LIMS1
3'UTR of LIMS1
(miRNA target sites are highlighted)		 
>LIMS1|NM_004987|3'UTR
   1 GTTCCTTTATTTTTTCTTTTCTATGCAAGATAAGAGATTACCAACATTACTTGTCTTGATCTACCCATATTTAAAGCTAT
  81 ATCTCAAAGCAGTTGAGAGAAGAGGACCTATATGAATGGTTTTATGTCATTTTTTTAATTAAAAAAGAAAAATTCATATA
 161 ATCGTGTTTAAAACACAAATGAAGTCAGTATTTGCCTTTGTTAACCCTTATCCATTTGTTGACATGTAGACTGTTTACAA
 241 AAAAAAAACACATGGTTAAATGTTAAATTTTAATTAAGGCCCCCAAAAATTAAATATAACTTTTTAAAATGAAAGGAGTC
 321 ACCTTTTACATGACTCAGGTGAAAAAACAGTATAAACATTAATTTACTTTGTGTTCAAAAGAAAATTCCAACTGCTGTTG
 401 GGGAAGGACACAGAAAAGAAAAATAACCACCCAAGAAAAACAAAAACAAGAAAAACAAATCTTATACAATCTTAGTATAT
 481 TTATCAAACTAGTAGCTAGAAAGTGAATATGCACATTACTAAGACAAAAAACAAGTGTAATTCAGAACTACTTGATTTTT
 561 TTTAGTTAAATGCAATAATTATTATGCTTAGTTTTATAACCTGCTCTCCTTGTGAATTCTTCCTTCAAATGATTACTTAA
 641 CGCAGTAGTAATAGCTAGCTGTAGGATGTCCTTTAAATTTTTGTGCAAAAAAAAATTTATACCAGGTATTTGGAAATATA
 721 CTTTACAATATTGGAAAATGAAGTATTTTTAATGTATTACAGCAATTATGTTTCTAAGCTTAATGTTAAGCATGTAGTCT
 801 TAGAATAGGACATGAAATTAAATTGTATGTAGCTTGGAATATATTGCTTCAGAAAACTGAATGTGTATGTCGGTCATATT
 881 GCCTTTATAACCATGCTAATATCTATGCTTTATACATACTCAAACTTGCCTTGCCTTAAAAACATACATACTACATACTT
 961 AAATCAGGAATTCTAGCCATCTCACAGAATACCAACTAAAACTAAGTGCATTGAGATCTGAGATTGGTAAACCCAGATTC
1041 ATTTACCACAGCTGTAATTAAGTTTTTAGAAACTATTCTCTTTTTGGGGAAATCCATTGAAGTTAATTTCTGTTATCTTA
1121 TTAGAAGAAAATGATGTTGATATGTGTTTCAGATTTTCCATTTGAAATCTTATAATTAATTTGATTTATTTACTGTAAGT
1201 AGGAGGTATAAATGACACTCTTAAATTGGAAGGAGGGGTGTTTTAGTGTCTGTTTTAGGTCAAAATTAGTGATTCTATTT
1281 TTATCAAAAGTTTTATCCTGAAGTTTCAGGACCACTCTTCCTTAATAAACTTGTTAATGGAAAGCGAGCTTTATGAACAT
1361 TTAAAAATGTTGCTGCTGCTTTGTTGCTTAAAAAGAAAGTTGCCAAGAGAGACTTCTTAGGGAAAATATTTGGGTTTTTT
1441 TTCCAAAAATTGCTGAAATATTGTTTTGCCATTTTTAAAAAGTCTCAGGTTATTACCACTCTGCCATTAAATATTTGTAT
1521 GCCTGCATTTTTAAAAATTCTGTGCATGTACTTTATGGAGTACATTCTATTTTTGTTTTCAGATACCCTACAACCAATTT
1601 TTTTTAGTAATCTTTTAGAATTGAAATTATCATAAATGATCGAGAATAATCATCACATAGTTTAAGATTGTATATGTTGA
1681 GTAGTTTAAAACAATCTTTGCATTTTACAGTAAGAATCAAAGTCCCTTCAGTGTGCCTTTGTCAGCTAATATGTGACCAG
1761 CAATGACAACCTTGGGAGTATTTATTAAATATTATGCTATGAATATAGGCAACACAGAACAGGGTTTGCAGTATAGCGTC
1841 TTGATGCTAAATTCTCATATACCTCTACACGAGAAATATGGAGGAGAAAAACAAGCATTTACATATATTCTTCGTCACTT
1921 TGAAGATGCATGGCCTGAACTCGACTGCTTGTGTTTGTTTACATATCAGGCATACCCAGGCATCTCCTGCAGCCAGAGGT
2001 TCCATTGCTGTCTTTGCTCAGTCCTCTTTTAAAATATGAATTAGTGGACAGGCACGGTGCCTCACACCTGTAATCCCAGC
2081 ACTTTGGGAGGTCGAGGCAGGTGGATCACGAGGTCAGGAGATCAAGACCATCCTGGCTACCACTGAAACCCCATCTCTAC
2161 TACAAAAAAATTAGCCGGGCGTGGTGGCGGGCACCTGCAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGGGA
2241 ACCCGGGAGGCAGAGCTTGCAGTGAGCCAAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGTCTCA
2321 AAAAAAATAAATAAATAAATTATGAATGAGTATTTTCTAGAAATTCAACTTGCTAAGCCTGTAATACTTAAGGGTAGTTT
2401 ATCTAGATACAGTACTTTCTTCCCTGATAAGTAGTATCATTGGAGCCCTTAGGTATAGGAGAAGAGGAAGAAGTTTAAAA
2481 AGTGTAAGTGGGCCGGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGGGGGCGGATCACGAGGTC
2561 AGGAGATCCAGACTATCCTGGCTAACAAGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAAAACATTAGCCAGGCGTG
2641 GTGGCGGGCGCTTGTAGTCCCAGCTACTCGGGAGGCTGAGGTAGGAGAATGGCTTGAACCCAGGAGGCGGAGCTTGCAGT
2721 GAGCCGAGATTGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAGTGTAAGTG
2801 GATTAAAAGAGAAACTTGGTCTAGTTCATAATATTTTTAATAGGGCTTTCCCTGGCTGCTGGAAAACTTAGGCCAGTAAG
2881 CATCTCTTTGTTTAAAGTCCTACAAGACAATTTGAAATAATTCATTGTTCATGCCAAAATTCTAAGTACTGTTTTTCTTA
2961 GCAAGTGTAACATAATCAGGAACAATGGGTACAAGTAAAACATTCTTTGGATGATATTCAAAGCCTTATTAGCACTGCAC
3041 CTGAATAATAGGTCATTTTGCCTCACTCATTTGCCAAAGTAGCCATTTCTAAGTTAAGGAAGTTTTTAGATAGGCTCATA
3121 GCCTTGTATTTCGTTTTAGATTGTAAGCTCAATGGCAGGGATACTATATTGGTAATTATGTTTTCATATAGCAACCACCA
3201 CAGTATATTCTTGGTGCTTAATAAATGTTTATAATTGTTAACAATAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gcggcccgagGGGCCCc 5'
                    |||||| 
Target 5' atggtgggaaCCCGGGa 3'
 2232 - 2248 120.00 -23.90
2 
miRNA  3' gcggCCCG--AGGGGCCcc 5'
              ||||  ||||:||  
Target 5' aataGGGCTTTCCCTGGct 3'
 2839 - 2857 119.00 -18.10
3 
miRNA  3' gcGGCCCGAGGGGCCCc 5'
            ||  ||| |:|||| 
Target 5' gtCCCAGCTACTCGGGa 3'
 2200 - 2216 111.00 -15.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN13927228 6 COSMIC
COSN30142439 17 COSMIC
COSN20836884 26 COSMIC
COSN31559322 29 COSMIC
COSN30153718 30 COSMIC
COSN30123948 56 COSMIC
COSN30511137 60 COSMIC
COSN30146819 96 COSMIC
COSN1221452 109 COSMIC
COSN24612403 239 COSMIC
COSN28847510 249 COSMIC
COSN29520362 249 COSMIC
COSN8981694 318 COSMIC
COSN1777645 324 COSMIC
COSN16042191 1128 COSMIC
COSN8981695 1140 COSMIC
COSN5125342 1204 COSMIC
COSN17183355 1347 COSMIC
COSN1221453 1958 COSMIC
COSN6201309 2046 COSMIC
COSN8264539 2232 COSMIC
COSN26341558 2434 COSMIC
COSN21643697 2459 COSMIC
COSN16363501 2572 COSMIC
COSN26468622 2632 COSMIC
COSN15030212 2670 COSMIC
COSN8981696 2970 COSMIC
COSN27057668 3103 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1342026571 2 dbSNP
rs1200488338 5 dbSNP
rs1326784375 5 dbSNP
rs754026131 10 dbSNP
rs768249488 21 dbSNP
rs1184255665 24 dbSNP
rs778519132 29 dbSNP
rs771275953 33 dbSNP
rs1157229633 35 dbSNP
rs367765190 36 dbSNP
rs371971613 37 dbSNP
rs1302387338 42 dbSNP
rs1400114145 43 dbSNP
rs1393712029 46 dbSNP
rs1473339213 49 dbSNP
rs770107313 50 dbSNP
rs775661598 52 dbSNP
rs896236140 55 dbSNP
rs1180330780 56 dbSNP
rs1199961643 60 dbSNP
rs558629353 68 dbSNP
rs1431135309 70 dbSNP
rs576831467 79 dbSNP
rs1013253164 80 dbSNP
rs1466743587 81 dbSNP
rs1272213665 82 dbSNP
rs1358205434 84 dbSNP
rs1471453169 90 dbSNP
rs1157220160 92 dbSNP
rs1238271091 94 dbSNP
rs1015382195 102 dbSNP
rs1311367851 105 dbSNP
rs772980586 106 dbSNP
rs1323148870 109 dbSNP
rs575379365 111 dbSNP
rs1375150609 113 dbSNP
rs1157237754 117 dbSNP
rs1027343668 120 dbSNP
rs1452049744 130 dbSNP
rs375231414 130 dbSNP
rs766433643 130 dbSNP
rs757571910 142 dbSNP
rs1251764478 145 dbSNP
rs1199170520 155 dbSNP
rs534634393 156 dbSNP
rs953971005 157 dbSNP
rs985885044 165 dbSNP
rs1204403397 171 dbSNP
rs1354131435 183 dbSNP
rs552723015 190 dbSNP
rs1231903156 195 dbSNP
rs1345854303 197 dbSNP
rs574472611 208 dbSNP
rs1437250095 215 dbSNP
rs1333084296 225 dbSNP
rs1316496065 232 dbSNP
rs965461812 233 dbSNP
rs1361509078 239 dbSNP
rs1433360744 239 dbSNP
rs988857137 239 dbSNP
rs913317441 242 dbSNP
rs1172705298 249 dbSNP
rs543385730 250 dbSNP
rs1226902889 274 dbSNP
rs149364279 276 dbSNP
rs1265007525 278 dbSNP
rs576715199 282 dbSNP
rs77409099 285 dbSNP
rs1240616155 286 dbSNP
rs1263157173 295 dbSNP
rs1355622054 303 dbSNP
rs1223146683 309 dbSNP
rs1270872207 332 dbSNP
rs1347204974 342 dbSNP
rs1268654247 350 dbSNP
rs1218178764 354 dbSNP
rs1341556458 357 dbSNP
rs1481967138 359 dbSNP
rs927554739 361 dbSNP
rs1413299636 363 dbSNP
rs1359136006 370 dbSNP
rs1335433588 371 dbSNP
rs1181126520 386 dbSNP
rs565391401 392 dbSNP
rs1415694419 393 dbSNP
rs1416683862 396 dbSNP
rs1169555563 398 dbSNP
rs1477914200 401 dbSNP
rs1425294688 405 dbSNP
rs1185577560 410 dbSNP
rs1250138205 413 dbSNP
rs1238041826 421 dbSNP
rs1212083571 422 dbSNP
rs1444207221 425 dbSNP
rs1348428692 428 dbSNP
rs1198278612 432 dbSNP
rs1318933724 436 dbSNP
rs1280302690 442 dbSNP
rs1231907752 447 dbSNP
rs1378825286 452 dbSNP
rs1419862437 453 dbSNP
rs1450761920 462 dbSNP
rs1161448706 466 dbSNP
rs182170429 488 dbSNP
rs1330150642 490 dbSNP
rs1055206069 504 dbSNP
rs1402100417 517 dbSNP
rs187210589 519 dbSNP
rs949052490 532 dbSNP
rs1036773346 556 dbSNP
rs896894532 556 dbSNP
rs1468494655 559 dbSNP
rs1367947484 569 dbSNP
rs370463440 576 dbSNP
rs1198134719 578 dbSNP
rs1297927871 582 dbSNP
rs1458266997 584 dbSNP
rs1260250901 585 dbSNP
rs1211984232 587 dbSNP
rs1373687216 602 dbSNP
rs755673210 606 dbSNP
rs1392763633 607 dbSNP
rs1230362327 610 dbSNP
rs559355777 612 dbSNP
rs1310068562 613 dbSNP
rs1446953510 618 dbSNP
rs826590 620 dbSNP
rs1323490578 624 dbSNP
rs190586709 628 dbSNP
rs561360408 637 dbSNP
rs549638424 638 dbSNP
rs1166718872 642 dbSNP
rs1398709194 643 dbSNP
rs889716195 644 dbSNP
rs73952510 650 dbSNP
rs1020036411 653 dbSNP
rs1240058032 658 dbSNP
rs201240262 660 dbSNP
rs34175526 661 dbSNP
rs1488305535 680 dbSNP
rs1247474581 687 dbSNP
rs965411340 698 dbSNP
rs1224320979 705 dbSNP
rs1339949701 713 dbSNP
rs1203609603 719 dbSNP
rs1285950008 726 dbSNP
rs1331148519 728 dbSNP
rs1355270168 735 dbSNP
rs1385713454 743 dbSNP
rs1251659601 744 dbSNP
rs1294919391 745 dbSNP
rs1359586248 752 dbSNP
rs988803455 752 dbSNP
rs1020409750 755 dbSNP
rs550800529 775 dbSNP
rs1254290232 779 dbSNP
rs979352801 780 dbSNP
rs570604174 793 dbSNP
rs534456864 800 dbSNP
rs927449274 804 dbSNP
rs1268386494 813 dbSNP
rs1184260315 815 dbSNP
rs546970558 818 dbSNP
rs143719220 828 dbSNP
rs1262875310 830 dbSNP
rs1218018610 833 dbSNP
rs113933190 835 dbSNP
rs917490762 841 dbSNP
rs1231977050 842 dbSNP
rs182766860 846 dbSNP
rs752449541 848 dbSNP
rs949081855 864 dbSNP
rs1302959835 868 dbSNP
rs187316397 869 dbSNP
rs1339618646 872 dbSNP
rs746641009 873 dbSNP
rs1401581315 877 dbSNP
rs1373627891 887 dbSNP
rs1302175743 894 dbSNP
rs778858108 895 dbSNP
rs1355498645 900 dbSNP
rs1178549643 906 dbSNP
rs1476937811 910 dbSNP
rs1423159976 917 dbSNP
rs1194900594 932 dbSNP
rs747925184 934 dbSNP
rs1479006180 938 dbSNP
rs1254760157 939 dbSNP
rs1463793848 940 dbSNP
rs826591 944 dbSNP
rs1483308490 948 dbSNP
rs115925898 949 dbSNP
rs1048713341 951 dbSNP
rs1452796831 956 dbSNP
rs1220297499 964 dbSNP
rs1353263887 965 dbSNP
rs558911364 966 dbSNP
rs1396497685 971 dbSNP
rs577352335 974 dbSNP
rs1304714963 980 dbSNP
rs1464105396 986 dbSNP
rs751387192 986 dbSNP
rs1019564208 987 dbSNP
rs1171638038 988 dbSNP
rs1479015375 990 dbSNP
rs1367044735 995 dbSNP
rs901078187 996 dbSNP
rs1424947026 1003 dbSNP
rs1258832267 1008 dbSNP
rs541208035 1010 dbSNP
rs1258314964 1016 dbSNP
rs1200061067 1018 dbSNP
rs1354036803 1025 dbSNP
rs1264590395 1028 dbSNP
rs1245219762 1037 dbSNP
rs1309069000 1042 dbSNP
rs1306987653 1055 dbSNP
rs1207696700 1082 dbSNP
rs1010259459 1086 dbSNP
rs1261552126 1124 dbSNP
rs1332305388 1127 dbSNP
rs17036617 1134 dbSNP
rs968798166 1137 dbSNP
rs530038879 1147 dbSNP
rs1163080521 1150 dbSNP
rs1458728617 1153 dbSNP
rs112634375 1170 dbSNP
rs1157319740 1173 dbSNP
rs1438540854 1174 dbSNP
rs1238207604 1175 dbSNP
rs1180152232 1180 dbSNP
rs1481745899 1180 dbSNP
rs532662935 1183 dbSNP
rs1266197028 1184 dbSNP
rs1358188299 1185 dbSNP
rs775437824 1189 dbSNP
rs958934328 1196 dbSNP
rs763033489 1198 dbSNP
rs1310140003 1203 dbSNP
rs917521811 1206 dbSNP
rs1444425619 1207 dbSNP
rs1430689211 1210 dbSNP
rs530742910 1215 dbSNP
rs190220826 1216 dbSNP
rs1367771427 1217 dbSNP
rs1296918976 1225 dbSNP
rs1419580007 1227 dbSNP
rs700879 1233 dbSNP
rs1469991684 1247 dbSNP
rs1338230600 1250 dbSNP
rs1328852559 1254 dbSNP
rs1376774079 1257 dbSNP
rs1385810199 1258 dbSNP
rs1199061103 1269 dbSNP
rs1429363856 1270 dbSNP
rs1260717838 1276 dbSNP
rs918221009 1295 dbSNP
rs1488598463 1296 dbSNP
rs1363960371 1323 dbSNP
rs1217302415 1346 dbSNP
rs1342884833 1347 dbSNP
rs1274486464 1362 dbSNP
rs528289912 1372 dbSNP
rs1347801799 1375 dbSNP
rs1048181695 1377 dbSNP
rs930038 1387 dbSNP
rs1361816621 1388 dbSNP
rs115040693 1405 dbSNP
rs1265162728 1406 dbSNP
rs1412275573 1413 dbSNP
rs1445384391 1415 dbSNP
rs1172834362 1419 dbSNP
rs1478779047 1421 dbSNP
rs1420980656 1428 dbSNP
rs1192755200 1432 dbSNP
rs1478017907 1434 dbSNP
rs780900434 1434 dbSNP
rs35092492 1435 dbSNP
rs535456446 1435 dbSNP
rs1243250673 1436 dbSNP
rs1325977396 1443 dbSNP
rs183258039 1443 dbSNP
rs901102514 1444 dbSNP
rs1218476103 1457 dbSNP
rs1010122093 1461 dbSNP
rs1197798034 1464 dbSNP
rs1272434962 1472 dbSNP
rs1446414348 1476 dbSNP
rs1041743709 1504 dbSNP
rs745485847 1512 dbSNP
rs1480929819 1516 dbSNP
rs1178179928 1526 dbSNP
rs750137290 1528 dbSNP
rs1000595151 1533 dbSNP
rs1399662768 1539 dbSNP
rs142742291 1541 dbSNP
rs1318369194 1546 dbSNP
rs1169443452 1549 dbSNP
rs1465947475 1552 dbSNP
rs755764773 1561 dbSNP
rs1180066603 1562 dbSNP
rs1472453264 1588 dbSNP
rs1237958066 1591 dbSNP
rs765994193 1598 dbSNP
rs959022834 1598 dbSNP
rs1256418612 1620 dbSNP
rs753308873 1627 dbSNP
rs1024401704 1629 dbSNP
rs535942976 1638 dbSNP
rs779878165 1639 dbSNP
rs1226944377 1640 dbSNP
rs778755156 1642 dbSNP
rs972252278 1643 dbSNP
rs1454129633 1656 dbSNP
rs920843157 1657 dbSNP
rs1330297322 1668 dbSNP
rs1446997998 1680 dbSNP
rs1355895954 1687 dbSNP
rs559193120 1703 dbSNP
rs1324916337 1711 dbSNP
rs1406503541 1724 dbSNP
rs952446801 1727 dbSNP
rs1414525105 1732 dbSNP
rs1165334242 1742 dbSNP
rs984180834 1744 dbSNP
rs1236389904 1751 dbSNP
rs1178284376 1752 dbSNP
rs373319648 1753 dbSNP
rs942414512 1758 dbSNP
rs1223333484 1761 dbSNP
rs922390686 1764 dbSNP
rs1248750900 1768 dbSNP
rs1319315531 1771 dbSNP
rs1350887464 1793 dbSNP
rs945859658 1795 dbSNP
rs1375162271 1796 dbSNP
rs1220921498 1798 dbSNP
rs1041688052 1803 dbSNP
rs904423018 1805 dbSNP
rs1435520703 1816 dbSNP
rs1490621666 1825 dbSNP
rs1202010526 1828 dbSNP
rs1304913821 1838 dbSNP
rs552522007 1839 dbSNP
rs541565875 1841 dbSNP
rs1158167610 1858 dbSNP
rs1419732301 1864 dbSNP
rs1410453290 1871 dbSNP
rs1189626525 1872 dbSNP
rs1469302998 1880 dbSNP
rs1488374564 1883 dbSNP
rs1158698710 1898 dbSNP
rs1056174757 1903 dbSNP
rs1371500962 1912 dbSNP
rs187735276 1914 dbSNP
rs1403034448 1915 dbSNP
rs1162892631 1921 dbSNP
rs700878 1934 dbSNP
rs1406598525 1943 dbSNP
rs139404421 1944 dbSNP
rs1334273583 1947 dbSNP
rs1218237604 1952 dbSNP
rs1441735456 1954 dbSNP
rs1024432945 1955 dbSNP
rs770154595 1958 dbSNP
rs1397879438 1959 dbSNP
rs780276056 1964 dbSNP
rs1298670626 1966 dbSNP
rs1454378116 1971 dbSNP
rs1174244352 1972 dbSNP
rs1432865972 1974 dbSNP
rs11902040 1984 dbSNP
rs1202126243 1985 dbSNP
rs1477040121 1987 dbSNP
rs1263123130 1988 dbSNP
rs1206173120 1991 dbSNP
rs530926649 1997 dbSNP
rs1486582170 1999 dbSNP
rs749361669 2000 dbSNP
rs1323866620 2006 dbSNP
rs1027891374 2008 dbSNP
rs1291749514 2020 dbSNP
rs1339523625 2027 dbSNP
rs56953948 2031 dbSNP
rs952378408 2035 dbSNP
rs11557828 2036 dbSNP
rs1278800238 2037 dbSNP
rs983823024 2046 dbSNP
rs1376853824 2048 dbSNP
rs910843588 2049 dbSNP
rs11896716 2052 dbSNP
rs192555747 2056 dbSNP
rs922338384 2057 dbSNP
rs528285272 2069 dbSNP
rs945889191 2072 dbSNP
rs1194546733 2077 dbSNP
rs1430860206 2079 dbSNP
rs546780754 2081 dbSNP
rs925910058 2083 dbSNP
rs1461329471 2086 dbSNP
rs935885799 2087 dbSNP
rs1442267003 2093 dbSNP
rs1055809762 2094 dbSNP
rs1385835369 2095 dbSNP
rs371898544 2099 dbSNP
rs1319922543 2102 dbSNP
rs1311900435 2103 dbSNP
rs1395542711 2104 dbSNP
rs1383536000 2108 dbSNP
rs568182149 2110 dbSNP
rs1045827459 2111 dbSNP
rs529022631 2114 dbSNP
rs897900714 2124 dbSNP
rs1410258712 2125 dbSNP
rs1164606260 2126 dbSNP
rs1329816508 2130 dbSNP
rs1356471845 2136 dbSNP
rs1450591942 2140 dbSNP
rs1314456524 2144 dbSNP
rs1384255584 2152 dbSNP
rs1244392881 2160 dbSNP
rs1176211665 2161 dbSNP
rs1250786296 2164 dbSNP
rs1457070101 2164 dbSNP
rs1248815177 2171 dbSNP
rs1268862706 2172 dbSNP
rs1246576993 2177 dbSNP
rs993651896 2178 dbSNP
rs1317311974 2179 dbSNP
rs1028214650 2180 dbSNP
rs1196703229 2181 dbSNP
rs550677253 2182 dbSNP
rs888042587 2183 dbSNP
rs1202561774 2185 dbSNP
rs1243206280 2189 dbSNP
rs141793399 2190 dbSNP
rs1017852505 2192 dbSNP
rs1156371856 2193 dbSNP
rs1372381389 2194 dbSNP
rs539416021 2198 dbSNP
rs1475647083 2199 dbSNP
rs1169398301 2213 dbSNP
rs111757006 2214 dbSNP
rs1222930168 2218 dbSNP
rs976400059 2220 dbSNP
rs1214619827 2222 dbSNP
rs1029438844 2224 dbSNP
rs1406923855 2226 dbSNP
rs1241387314 2227 dbSNP
rs1397814828 2231 dbSNP
rs1329536345 2234 dbSNP
rs1316875817 2235 dbSNP
rs1326338674 2236 dbSNP
rs1228666818 2237 dbSNP
rs1283084421 2237 dbSNP
rs1405929900 2238 dbSNP
rs1368070204 2239 dbSNP
rs967094814 2242 dbSNP
rs187772491 2244 dbSNP
rs826592 2245 dbSNP
rs1222541902 2246 dbSNP
rs1376689731 2247 dbSNP
rs1199970082 2253 dbSNP
rs553180405 2261 dbSNP
rs1462293669 2267 dbSNP
rs1192799575 2270 dbSNP
rs192208558 2275 dbSNP
rs1261003727 2277 dbSNP
rs1447508367 2278 dbSNP
rs760977576 2280 dbSNP
rs1262735172 2290 dbSNP
rs950084412 2297 dbSNP
rs1347699194 2298 dbSNP
rs1426954771 2307 dbSNP
rs1430583305 2310 dbSNP
rs1479947406 2311 dbSNP
rs1319763785 2314 dbSNP
rs1176013808 2315 dbSNP
rs1045690067 2320 dbSNP
rs1176635235 2320 dbSNP
rs1470837625 2321 dbSNP
rs1430192555 2325 dbSNP
rs377132238 2325 dbSNP
rs1243767642 2328 dbSNP
rs765975328 2328 dbSNP
rs1440713171 2329 dbSNP
rs557033972 2329 dbSNP
rs1156864414 2341 dbSNP
rs1384960882 2342 dbSNP
rs1383257737 2349 dbSNP
rs1326132608 2351 dbSNP
rs1049230443 2358 dbSNP
rs1214319437 2368 dbSNP
rs1340771004 2370 dbSNP
rs184657324 2378 dbSNP
rs1272422220 2379 dbSNP
rs1344030025 2393 dbSNP
rs1445197489 2402 dbSNP
rs1381320717 2406 dbSNP
rs1337004872 2408 dbSNP
rs887980870 2410 dbSNP
rs1397631886 2413 dbSNP
rs1007718137 2414 dbSNP
rs188978404 2420 dbSNP
rs1421583969 2426 dbSNP
rs1161322096 2428 dbSNP
rs1442888120 2428 dbSNP
rs1404678743 2430 dbSNP
rs1283581859 2433 dbSNP
rs1325206336 2435 dbSNP
rs1236576378 2449 dbSNP
rs1236336336 2452 dbSNP
rs115018518 2454 dbSNP
rs745985765 2457 dbSNP
rs115081828 2460 dbSNP
rs997866923 2462 dbSNP
rs1359318096 2467 dbSNP
rs540748936 2474 dbSNP
rs967125949 2483 dbSNP
rs1374265698 2485 dbSNP
rs1297187471 2491 dbSNP
rs1490130562 2496 dbSNP
rs1199858149 2499 dbSNP
rs1356018706 2500 dbSNP
rs977537762 2501 dbSNP
rs540509022 2504 dbSNP
rs561896189 2511 dbSNP
rs1366080231 2512 dbSNP
rs1164369660 2516 dbSNP
rs957469254 2529 dbSNP
rs1406084131 2537 dbSNP
rs991327611 2539 dbSNP
rs529089399 2540 dbSNP
rs192789097 2542 dbSNP
rs1490347914 2543 dbSNP
rs915838271 2544 dbSNP
rs112643030 2548 dbSNP
rs376347570 2549 dbSNP
rs11557827 2553 dbSNP
rs1369355083 2555 dbSNP
rs1375042436 2556 dbSNP
rs971265782 2562 dbSNP
rs1404106236 2563 dbSNP
rs981422809 2569 dbSNP
rs560417812 2570 dbSNP
rs919219431 2579 dbSNP
rs929304984 2584 dbSNP
rs1049645706 2586 dbSNP
rs1305762945 2589 dbSNP
rs1197781728 2590 dbSNP
rs1480278844 2591 dbSNP
rs1270238071 2595 dbSNP
rs1335861602 2596 dbSNP
rs1484618811 2598 dbSNP
rs762740627 2600 dbSNP
rs199552338 2601 dbSNP
rs1215847920 2605 dbSNP
rs1276051830 2617 dbSNP
rs909285903 2617 dbSNP
rs1223038463 2619 dbSNP
rs1293661447 2626 dbSNP
rs1345842556 2626 dbSNP
rs1479503395 2630 dbSNP
rs943554767 2632 dbSNP
rs532517347 2633 dbSNP
rs1250034504 2635 dbSNP
rs1288431276 2636 dbSNP
rs369787222 2638 dbSNP
rs35913018 2639 dbSNP
rs997732579 2641 dbSNP
rs1180553657 2644 dbSNP
rs1383996681 2646 dbSNP
rs184727223 2647 dbSNP
rs373064183 2649 dbSNP
rs902892360 2650 dbSNP
rs1460747583 2651 dbSNP
rs1486528806 2651 dbSNP
rs377196072 2653 dbSNP
rs1324032547 2657 dbSNP
rs1264830671 2662 dbSNP
rs998526514 2664 dbSNP
rs1306903559 2667 dbSNP
rs189196289 2670 dbSNP
rs781309528 2671 dbSNP
rs957125986 2672 dbSNP
rs1334995661 2675 dbSNP
rs1452250726 2682 dbSNP
rs535020228 2683 dbSNP
rs1339183382 2684 dbSNP
rs1460775838 2686 dbSNP
rs1373025207 2694 dbSNP
rs1013184500 2695 dbSNP
rs1429812648 2696 dbSNP
rs1246643652 2700 dbSNP
rs113420245 2701 dbSNP
rs1314699223 2709 dbSNP
rs1305581609 2710 dbSNP
rs1244580501 2717 dbSNP
rs1193866316 2718 dbSNP
rs1203498923 2726 dbSNP
rs867019463 2727 dbSNP
rs1022725716 2731 dbSNP
rs1200663737 2732 dbSNP
rs1022295008 2735 dbSNP
rs971296943 2738 dbSNP
rs1317354548 2742 dbSNP
rs546880566 2743 dbSNP
rs1416524999 2744 dbSNP
rs980847335 2745 dbSNP
rs1427158683 2749 dbSNP
rs1170154366 2752 dbSNP
rs1373361178 2756 dbSNP
rs866399072 2757 dbSNP
rs1364224554 2759 dbSNP
rs1162435662 2764 dbSNP
rs1444648197 2765 dbSNP
rs1386709317 2769 dbSNP
rs1334224702 2772 dbSNP
rs1404730457 2773 dbSNP
rs1251035702 2776 dbSNP
rs1452678512 2776 dbSNP
rs1286209968 2777 dbSNP
rs1360172670 2777 dbSNP
rs35207613 2777 dbSNP
rs371066206 2777 dbSNP
rs866825320 2777 dbSNP
rs1304538671 2778 dbSNP
rs1359757301 2780 dbSNP
rs1237098584 2787 dbSNP
rs1335377704 2790 dbSNP
rs1308213431 2792 dbSNP
rs1213841589 2793 dbSNP
rs926809003 2794 dbSNP
rs950805937 2795 dbSNP
rs960882601 2800 dbSNP
rs984790213 2807 dbSNP
rs1424777546 2816 dbSNP
rs866406104 2818 dbSNP
rs1366839769 2819 dbSNP
rs909304696 2835 dbSNP
rs531917945 2839 dbSNP
rs568364576 2842 dbSNP
rs1039616307 2848 dbSNP
rs1210876595 2852 dbSNP
rs1200011244 2873 dbSNP
rs1239760011 2877 dbSNP
rs1485177693 2887 dbSNP
rs923392895 2887 dbSNP
rs1186362838 2891 dbSNP
rs933474955 2901 dbSNP
rs1350321052 2903 dbSNP
rs1261469869 2907 dbSNP
rs1230621974 2909 dbSNP
rs535607780 2910 dbSNP
rs1262888532 2933 dbSNP
rs1042697550 2934 dbSNP
rs1478970914 2937 dbSNP
rs557186431 2947 dbSNP
rs1428104155 2965 dbSNP
rs902756577 2966 dbSNP
rs1381148553 2971 dbSNP
rs998952863 2974 dbSNP
rs1054104019 2977 dbSNP
rs180790714 2981 dbSNP
rs1428285062 2986 dbSNP
rs1012635030 2989 dbSNP
rs1289308761 2990 dbSNP
rs2433848 2994 dbSNP
rs749907027 2996 dbSNP
rs1191127694 3000 dbSNP
rs2433849 3022 dbSNP
rs1262730221 3026 dbSNP
rs1210769009 3036 dbSNP
rs1002648758 3037 dbSNP
rs1064830 3041 dbSNP
rs1347819100 3047 dbSNP
rs1281669616 3050 dbSNP
rs1323049853 3069 dbSNP
rs1268876357 3077 dbSNP
rs1226064274 3078 dbSNP
rs1326465370 3083 dbSNP
rs1064831 3090 dbSNP
rs1219959543 3102 dbSNP
rs950636870 3105 dbSNP
rs985207762 3112 dbSNP
rs1337230546 3117 dbSNP
rs1016230547 3118 dbSNP
rs558157682 3120 dbSNP
rs1167214438 3122 dbSNP
rs1280815122 3127 dbSNP
rs1475137253 3129 dbSNP
rs1315148524 3133 dbSNP
rs1190558596 3134 dbSNP
rs779788234 3137 dbSNP
rs1242744804 3138 dbSNP
rs1204723880 3139 dbSNP
rs1287321877 3141 dbSNP
rs1195684598 3153 dbSNP
rs1340651794 3156 dbSNP
rs1064832 3157 dbSNP
rs974864742 3160 dbSNP
rs1197687663 3170 dbSNP
rs1381668519 3177 dbSNP
rs568336901 3180 dbSNP
rs1478143290 3189 dbSNP
rs1064834 3201 dbSNP
rs1192508148 3203 dbSNP
rs1327910953 3206 dbSNP
rs1410503709 3211 dbSNP
rs933506281 3215 dbSNP
rs1384852489 3219 dbSNP
rs1399572118 3220 dbSNP
rs1473992391 3224 dbSNP
rs1159770312 3231 dbSNP
rs1181500354 3232 dbSNP
rs1362350223 3233 dbSNP
rs1438970119 3236 dbSNP
rs1422557458 3240 dbSNP
rs371035912 3243 dbSNP
rs924207644 3245 dbSNP
rs3180247 3246 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions BT474
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1395167. RNA binding protein: AGO. Condition:BT474 AGO HITS-CLIP Replicate 2 ...

- Pillai MM; Gillen AE; Yamamoto TM; Kline E; et al., 2014, Breast cancer research and treatment.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gcggcccgagggGCCCc 5'
                      |||| 
Target 5' ------------CGGGa 3'
 		1 - 5
2 
miRNA  3' gcggcccGAGGGGCCcc 5'
                 | || | |  
Target 5' aagaucaCGCCACUG-- 3'
 		26 - 40
Article - Pillai MM; Gillen AE; Yamamoto TM; Kline E; et al.
- Breast cancer research and treatment, 2014
miRNAs regulate the expression of genes in both normal physiology and disease. While miRNAs have been demonstrated to play a pivotal role in aspects of cancer biology, these reports have generally focused on the regulation of single genes. Such single-gene approaches have significant limitations, relying on miRNA expression levels and heuristic predictions of mRNA-binding sites. This results in only circumstantial evidence of miRNA-target interaction and typically leads to large numbers of false positive predictions. Here, we used a genome-wide approach (high-throughput sequencing of RNA isolated by crosslinking immunoprecipitation, HITS-CLIP) to define direct miRNA-mRNA interactions in three breast cancer subtypes (estrogen receptor positive, Her2 amplified, and triple negative). Focusing on steroid receptor signaling, we identified two novel regulators of the ER pathway (miR-9-5p and miR-193a/b-3p), which together target multiple genes involved in ER signaling. Moreover, this approach enabled the definition of miR-9-5p as a global regulator of steroid receptor signaling in breast cancer. We show that miRNA targets and networks defined by HITS-CLIP under physiologic conditions are predictive of patient outcomes and provide global insight into miRNA regulation in breast cancer.
LinkOut: [PMID: 24906430]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_004987 | 3UTR | AACCCGGGAGGCAGAGCUUGCAGUGAGCCAAGAUCACGCCACUGCACUCCAGCCUGGGCAACAGAGCAAGACUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_004987 | 3UTR | GAGGCAGAGCUUGCAGUGAGCCAAGAUCACGCCACUGCACUCCAGCCUGGGCAACAGAGCAAGACUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_004987 | 3UTR | GAACCCGGGAGGCAGAGCUUGCAGUGAGCCAAGAUCACGCCACUGCACUCCAGCCUGGGCAACAGAGCAAGACUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_004987 | 3UTR | GAGGCAGAGCUUGCAGUGAGCCAAGAUCACGCCACUGCACUCCAGCCUGGGCAACAGAGCAAGACUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_001193488 | 3UTR | GAAUGGUGGGAACCCGGGAGGCAGAGCUUGCAGUGAGCCAAGAUCACGCCACUGCACUCCAGCCUGGGCAACAGAGCAAGACUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_004987 | 3UTR | AACCCGGGAGGCAGAGCUUGCAGUGAGCCAAGAUCACGCCACUGCACUCCAGCCUGGGCAACAGAGCAAGACUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1395167
Method / RBP HITS-CLIP / AGO
Cell line / Condition BT474 / BT474 AGO HITS-CLIP Replicate 2
Location of target site ENST00000393310.1 | 3UTR | CGGGAGGCAGAGCUUGCAGUGAGCCAAGAUCACGCCACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 24906430 / GSE57855
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
119 hsa-miR-4532 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT451366 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT451448 ZNF556 zinc finger protein 556 2 4
MIRT458550 CYP2B6 cytochrome P450 family 2 subfamily B member 6 2 2
MIRT460274 SLC26A2 solute carrier family 26 member 2 2 2
MIRT460365 TXNDC16 thioredoxin domain containing 16 2 4
MIRT460539 TM4SF5 transmembrane 4 L six family member 5 2 2
MIRT463626 YY1 YY1 transcription factor 2 2
MIRT468524 SERTAD2 SERTA domain containing 2 2 4
MIRT469966 PTPRF protein tyrosine phosphatase, receptor type F 2 8
MIRT470076 PTGES2 prostaglandin E synthase 2 2 2
MIRT474926 KCTD20 potassium channel tetramerization domain containing 20 2 2
MIRT479976 CARD10 caspase recruitment domain family member 10 2 2
MIRT485533 GPRIN1 G protein regulated inducer of neurite outgrowth 1 2 2
MIRT485939 ECSIT ECSIT signalling integrator 2 4
MIRT486421 RXRA retinoid X receptor alpha 2 2
MIRT487665 HPCAL1 hippocalcin like 1 2 4
MIRT488113 POU3F1 POU class 3 homeobox 1 2 4
MIRT490648 FEM1A fem-1 homolog A 2 2
MIRT491313 LRFN1 leucine rich repeat and fibronectin type III domain containing 1 2 2
MIRT491345 CPNE5 copine 5 2 2
MIRT492688 PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2 2
MIRT496879 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT499243 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT508211 SLC35E1 solute carrier family 35 member E1 2 2
MIRT532712 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT540807 SLC35F5 solute carrier family 35 member F5 2 2
MIRT563529 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT607723 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT608089 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT618519 SELPLG selectin P ligand 2 2
MIRT624702 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT624769 AKR1D1 aldo-keto reductase family 1 member D1 2 2
MIRT629974 MRPL36 mitochondrial ribosomal protein L36 2 2
MIRT631355 ZFP82 ZFP82 zinc finger protein 2 2
MIRT631425 CDNF cerebral dopamine neurotrophic factor 2 2
MIRT631664 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT631734 SF3B1 splicing factor 3b subunit 1 2 2
MIRT632333 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT632418 SLC30A5 solute carrier family 30 member 5 2 2
MIRT632530 PSMB2 proteasome subunit beta 2 2 2
MIRT633263 LDLR low density lipoprotein receptor 2 2
MIRT634326 SLC43A2 solute carrier family 43 member 2 2 2
MIRT634752 CRCP CGRP receptor component 2 2
MIRT635411 KIAA1614 KIAA1614 2 2
MIRT636280 RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase 2 2
MIRT636290 RAD51L3-RFFL RAD51L3-RFFL readthrough 2 2
MIRT641737 TXNL1 thioredoxin like 1 2 2
MIRT643527 ERAP2 endoplasmic reticulum aminopeptidase 2 2 2
MIRT643554 C11orf70 chromosome 11 open reading frame 70 2 2
MIRT647026 NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 2 2
MIRT647297 RBM43 RNA binding motif protein 43 2 2
MIRT648123 SEMA3E semaphorin 3E 2 4
MIRT648610 TPCN2 two pore segment channel 2 2 2
MIRT648716 IL10RB interleukin 10 receptor subunit beta 2 2
MIRT649424 CDC14B cell division cycle 14B 2 2
MIRT650028 DSG3 desmoglein 3 2 2
MIRT650280 TAS2R5 taste 2 receptor member 5 2 2
MIRT654238 RNF115 ring finger protein 115 2 2
MIRT657031 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT658406 FAM212B family with sequence similarity 212 member B 2 2
MIRT661079 FFAR2 free fatty acid receptor 2 2 2
MIRT661528 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT661875 PDLIM5 PDZ and LIM domain 5 2 2
MIRT662099 ZNF419 zinc finger protein 419 2 2
MIRT663637 HM13 histocompatibility minor 13 2 2
MIRT663702 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663844 TRIM72 tripartite motif containing 72 2 2
MIRT664768 MESDC2 mesoderm development LRP chaperone 2 2
MIRT665480 VSTM4 V-set and transmembrane domain containing 4 2 2
MIRT666532 RNF157 ring finger protein 157 2 2
MIRT668106 GK5 glycerol kinase 5 (putative) 2 2
MIRT669741 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT671009 MOB4 MOB family member 4, phocein 2 2
MIRT671582 SPIRE2 spire type actin nucleation factor 2 2 2
MIRT673260 INO80 INO80 complex subunit 2 2
MIRT673532 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT674713 FAM73A mitoguardin 1 2 2
MIRT675204 ZNF554 zinc finger protein 554 2 2
MIRT676487 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT676704 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT676850 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT676854 RAB3B RAB3B, member RAS oncogene family 2 2
MIRT676914 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT676999 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT677187 PDE12 phosphodiesterase 12 2 2
MIRT677472 SLC7A11 solute carrier family 7 member 11 2 2
MIRT677561 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT677778 FKTN fukutin 2 2
MIRT677895 DCP1A decapping mRNA 1A 2 2
MIRT677995 GATC glutamyl-tRNA amidotransferase subunit C 2 2
MIRT678238 HMGB1 high mobility group box 1 2 4
MIRT678312 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT678436 PDE4C phosphodiesterase 4C 2 2
MIRT678479 RNF222 ring finger protein 222 2 2
MIRT678590 ZNF91 zinc finger protein 91 2 2
MIRT678862 SLC7A14 solute carrier family 7 member 14 2 2
MIRT679240 LRP10 LDL receptor related protein 10 2 2
MIRT679387 WDR92 WD repeat domain 92 2 2
MIRT679500 ZNF106 zinc finger protein 106 2 2
MIRT679580 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT679826 TMEM106B transmembrane protein 106B 2 2
MIRT679859 ZFP30 ZFP30 zinc finger protein 2 2
MIRT680472 C3 complement C3 2 2
MIRT683698 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT684267 PRPF4 pre-mRNA processing factor 4 2 2
MIRT689404 ZNF573 zinc finger protein 573 2 2
MIRT694756 ZNF843 zinc finger protein 843 2 2
MIRT695955 FANCM Fanconi anemia complementation group M 2 2
MIRT696365 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT700681 PPAP2B phospholipid phosphatase 3 2 2
MIRT701214 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT702195 LRRC58 leucine rich repeat containing 58 2 2
MIRT706799 RAI1 retinoic acid induced 1 2 2
MIRT711086 NEUROD2 neuronal differentiation 2 2 2
MIRT715997 RGS12 regulator of G protein signaling 12 2 2
MIRT716399 SEPT5 septin 5 2 2
MIRT718442 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT722159 ARHGAP40 Rho GTPase activating protein 40 2 2
MIRT724960 PTK6 protein tyrosine kinase 6 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4532 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4532 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant High Gallbladder Cancer cell line (GBC-SD, NOZ)
hsa-miR-4532 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4532 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4532 Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4532 Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4532 Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4532 Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer tissue
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4532 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4532 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (mitochondrial RNA)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-4532 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4532 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-4532 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4532 Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4532 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (OVSAHO)

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