miRTarBase - #MIRT608089


—
pre-miRNA Information
pre-miRNA hsa-mir-4532   
Genomic Coordinates chr20: 57895394 - 57895444
Description Homo sapiens miR-4532 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4532
Sequence 6| CCCCGGGGAGCCCGGCG |22
Evidence Experimental
Experiments Illumina
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CRISPLD2   
Synonyms CRISP11, LCRISP2, LGL1
Description cysteine rich secretory protein LCCL domain containing 2
Transcript NM_031476   
Expression
Putative miRNA Targets on CRISPLD2
3'UTR of CRISPLD2
(miRNA target sites are highlighted)		 
>CRISPLD2|NM_031476|3'UTR
   1 ATTTCCAGCACCAGGGGAGAAGGGGCGTCTTCAGGAGGGCTTCGGGGTTTTGCTTTTATTTTTATTTTGTCATTGCGGGG
  81 TATATGGAGAGTCAGGAAACTTCCTTTGACTGATGTTCAGTGTCCATCACTTTGTGGCCTGTGGGTGAGGTGACATCTCA
 161 TCCCCTCACTGAAGCAACAGCATCCCAAGGTGCTCAGCCGGACTCCCTGGTGCCTGATCCTGCTGGGGCCTGGGGGTCTC
 241 CATCTGGACGTCCTCTCTCCTTTAGAGATCTGAGCTGTCTCTTAAAGGGGACAGTTGCCCAAAATGTTCCTTGCTATGTG
 321 TTCTTCTGTTGGTGGAGGAAGTTGATTTCAACCTCCCTGCCAAAAGAACAAACCATTTGAAGCTCACAATTGTGAAGCAT
 401 TCACGGCGTCGGAAGAGGCCTTTTGAGCAAGCGCCAATGAGTTTCAGGAATGAAGTAGAAGGTAGTTATTTAAAAATAAA
 481 AAACACAGTCCGTCCCTACCAATAGAGGAAAATGGTTTTAATGTTTGCTGGTCAGACAGACAAATGGGCTAGAGTAAGAG
 561 GGCTGCGGGTATGAGAGACCCCGGCTCCGCCCTGGCACGTGTCCTTGCTGGCGGCCCGCCACAGGCCCCCTTCAATGGCC
 641 GCATTCAGGATGGCTCTATACACAGCAGTGCTGGTTTATGTAGAGTTCAGCAGTCACTTCAGAGATGTATCTTGTCTTTG
 721 TCAGGCCCTTCGTCTTCATGGCCCACCTGTTTTCTGCCGTGACCTTTGGTCCCATTGAGGACTAAGGATCGGGACCCTTT
 801 CTTTACCCCCTACCCGTTGTGGCTCCCACCCTGCCTCGGACTGGTTTACGTGTCCTGGTTCACACCCAGGACTTTTCTTT
 881 GCAAGCGAACCTGTTTGAAGCCCAAGTCTTAACTCCTGGTCTCGTAAGGTTCCACTGAGACGAGATGTCTGAGAACAACC
 961 AAAGAAGGCCTGCTCTTTGCTGCTTTTAAAAAATGACAATTAAATGTGCAGATTCCCCACGCACCCGATGACCTATTTTT
1041 TCAGCCGTGGGAGGAATGGAGTCTTTGGTACATTCCTCACCGAGGTTAGCAGCTCAGTTTGTGGTTATGAAACCGTCTGT
1121 GGCCTCATGACAGCGAGAGATGGGAATACACTAGAAGGATCTCTTTTCCTGTTTTCGTGAAACGACTCTTGCCAAACGTT
1201 CCCGAGGCGCCAAGGAGTGTAGTACACCCTGGCTGCCATCACTCTATAAAAGTGCTTCATGAGCCCAGACCAAAAGCCCA
1281 CAGTGAAATGAAGTACCCTTTTGTAAATAGCATTTTTTTGCAGAAGGTGAAAATTCCACTCTCTACCACCGGGCCAGCCA
1361 ATAGATCACTTTGGTGAATGCTAGTTTCAAATTTGATTCAAAATATTTCTTAGGTGAAAGAACTAGCAGAAAGTCAAAAA
1441 CTAAGATACTGTAGACTGGACAAGAAATTCTACCTGGGCACCTAGGTGATGCCTTCTTTCTTTGATTGCCTTTCTAATAA
1521 ATGCAGAATCTGAAGGTAAATAGGTTTAAAACAAAACAAAAACCCACCCCTTTAAGGAGTTGGTAAAAAGCAGTTCAACT
1601 CTTAGCTTGACTGAGCTAAAATTCACAGGACTACGTGCTTTGTGCATTGTAGTCTAGTCGTAATTCATAGGTACTGACTC
1681 CTCAGCCCCAAATGTCGGAGAGGAAGAATTCGGTCAGCCTGTCAGGTCGTGAGTCCAGTTACCACCAAACATCTGGGAAA
1761 CTTCTGGGTGCTGGGTGCTCTGCTGCTGGACTTTTGTGGCTGTGTCTGTGTCTGCAAGATAAATTAGATCGCCCTGTGGG
1841 GTTTGCAGAATTAGTGAAGGGTCCAGGACGATCCCAGTGGGCTCGCTTCCAAAGCATCCCACTCAAGGGAGACTTGAAAC
1921 TTCCAGTGTGAGTTGACCCCATCATTTAAAAATAAAGTCCCCGGGTTCCTTAATGCCTCCTTCACTGGGCCTTCCTAGCA
2001 GGATAGAAAGTCCTTGCCCAGAGCAGGACCTGGCTGTCTTTTTTTTTTTTTTTTTTTTTTTCCCGAGACCAAGTTTCACT
2081 CTGTTGCCCAAGGTAGAGTGCAGTGGCGTGATCTCTGCTCATTGCAACTGCCGCCTCCCGGGTTCAAGCAATTCTCATGC
2161 ATCAGCCTCCCAAGTACCTGGGACTACAGGCGTGAGCTACCATGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGT
2241 TTCATTATGTTGGCCAGGCTGGTCTCGAACTCCTTACCTCAGGTGATCCACCCACCTTGGCCTCCCGAAGTGCTGGGATT
2321 ACAGGCATGAGCCACTGCGCCCGGCCATGGACCTGGCTGTCTTTATCATCCCCACAAACATTTTGAAACTGGAATATTTG
2401 TCTTCAGAAAATGGAAACAAGACTATAAATGATAAGCCCTGTCCCTAGCACCACCTCTCCTGTGTGTGGAATAGAGGCCC
2481 CTCGTGCTACCAACACTTACCCTGTGTTTAAAAAGATCTTGTACCAAGCCAACGGCGTTCCTGGCTCTCCTGCCCACAGG
2561 ATGAACATTTTCGGCTTCCTTAGGAGTTTTGCCCTACCGTATTCCAAAGCGTGTGCTGGTTTCTCATATTGTCTGTAGGC
2641 TCACTCAGCCCGCAGTTTATGTGTGTGCTTTTTTCTATGAAAAATGATGTATTTTGCTACTTCCTGTGTACAAAGTTTTA
2721 TTGTAAATGTTTTTTGTGCTTTGCATGAACAGGGGCCACGTTGTTGCAATTGTTTCAGTAGAACTGGTTTGATTTCTAAA
2801 ATGTTCCTGTAACATATCTTTTATGAACAAATCTGAACAATTTGTGAAATAAAACATTGAAAACCATCAAAAAAAAAAAA
2881 AAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gcggcccgAGGGGCCCc 5'
                  |||||||| 
Target 5' aaataaagTCCCCGGGt 3'
 1950 - 1966 145.00 -17.00
2 
miRNA  3' gcGGCCCGAGGGGCCcc 5'
            |||| |||||:||  
Target 5' agCCGGACTCCCTGGtg 3'
 196 - 212 131.00 -28.50
3 
miRNA  3' gcggccCGAGGGGCCCc 5'
                || :|||||| 
Target 5' actgccGCCTCCCGGGt 3'
 2127 - 2143 131.00 -21.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31510342 13 COSMIC
COSN30455989 16 COSMIC
COSN26971890 17 COSMIC
COSN13694688 27 COSMIC
COSN1191742 28 COSMIC
COSN30156256 44 COSMIC
COSN26971893 45 COSMIC
COSN26971888 59 COSMIC
COSN30145355 62 COSMIC
COSN31530504 67 COSMIC
COSN1081729 77 COSMIC
COSN32053554 90 COSMIC
COSN7157106 93 COSMIC
COSN30491065 104 COSMIC
COSN23822119 398 COSMIC
COSN8673542 590 COSMIC
COSN17078470 1056 COSMIC
COSN1711703 1136 COSMIC
COSN26049476 1320 COSMIC
COSN31961243 1775 COSMIC
COSN29988050 1851 COSMIC
COSN26418297 1882 COSMIC
COSN9445252 2171 COSMIC
COSN31961244 2345 COSMIC
COSN5413268 2438 COSMIC
COSN31535744 2803 COSMIC
COSN22626510 2866 COSMIC
rs79754226 1418 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1353429061 1 dbSNP
rs1351831453 3 dbSNP
rs376397982 10 dbSNP
rs1274008197 12 dbSNP
rs186226489 13 dbSNP
rs879115641 15 dbSNP
rs770240749 16 dbSNP
rs776016770 17 dbSNP
rs749460169 18 dbSNP
rs768999596 20 dbSNP
rs1291472962 21 dbSNP
rs774499086 22 dbSNP
rs1220421651 26 dbSNP
rs761933782 27 dbSNP
rs372991636 28 dbSNP
rs1190928597 29 dbSNP
rs1388791710 30 dbSNP
rs1449461783 33 dbSNP
rs1164280516 34 dbSNP
rs1024813454 35 dbSNP
rs1416116431 38 dbSNP
rs1033244890 44 dbSNP
rs773163417 45 dbSNP
rs1403786304 48 dbSNP
rs760553173 52 dbSNP
rs753635886 53 dbSNP
rs754834321 57 dbSNP
rs766088331 60 dbSNP
rs764854851 65 dbSNP
rs1364347445 69 dbSNP
rs752340166 70 dbSNP
rs1285415234 72 dbSNP
rs777176792 73 dbSNP
rs746334368 75 dbSNP
rs559737670 77 dbSNP
rs749661522 78 dbSNP
rs1210968444 81 dbSNP
rs769195714 82 dbSNP
rs528907599 85 dbSNP
rs748352709 86 dbSNP
rs772143239 88 dbSNP
rs1471817484 90 dbSNP
rs773179462 97 dbSNP
rs1183088427 99 dbSNP
rs1418776465 100 dbSNP
rs1248476121 101 dbSNP
rs1412967468 103 dbSNP
rs760539486 105 dbSNP
rs766300171 107 dbSNP
rs941939122 108 dbSNP
rs776607682 109 dbSNP
rs1336041575 113 dbSNP
rs1338644391 114 dbSNP
rs200918687 116 dbSNP
rs764980618 117 dbSNP
rs1330756740 121 dbSNP
rs1226243488 125 dbSNP
rs752352998 126 dbSNP
rs562532236 127 dbSNP
rs758006312 129 dbSNP
rs1281259176 133 dbSNP
rs1304194998 141 dbSNP
rs1441260553 142 dbSNP
rs531578597 143 dbSNP
rs755223563 146 dbSNP
rs918919880 147 dbSNP
rs756890289 150 dbSNP
rs1252585636 153 dbSNP
rs780689797 154 dbSNP
rs751340304 156 dbSNP
rs911915050 156 dbSNP
rs754439025 157 dbSNP
rs1411533173 160 dbSNP
rs755355892 163 dbSNP
rs760998642 164 dbSNP
rs1159689160 165 dbSNP
rs1453281807 166 dbSNP
rs972373667 168 dbSNP
rs1178531897 175 dbSNP
rs920743676 178 dbSNP
rs1252454143 183 dbSNP
rs551361852 190 dbSNP
rs1055544894 197 dbSNP
rs571549237 200 dbSNP
rs1051487612 201 dbSNP
rs527608139 208 dbSNP
rs1349025995 221 dbSNP
rs943529770 223 dbSNP
rs1258534256 224 dbSNP
rs1324738179 229 dbSNP
rs1347892795 229 dbSNP
rs1450364555 231 dbSNP
rs1874008 232 dbSNP
rs904722850 233 dbSNP
rs1382521882 236 dbSNP
rs1181093591 241 dbSNP
rs566883467 250 dbSNP
rs999158707 251 dbSNP
rs1270356987 253 dbSNP
rs1394544309 253 dbSNP
rs748376639 254 dbSNP
rs535945432 255 dbSNP
rs1391284558 256 dbSNP
rs1000442335 260 dbSNP
rs1445585711 261 dbSNP
rs1031968488 264 dbSNP
rs1258712923 266 dbSNP
rs140671161 272 dbSNP
rs3803632 278 dbSNP
rs1024369953 280 dbSNP
rs560803451 288 dbSNP
rs374468416 291 dbSNP
rs1474152244 298 dbSNP
rs538468006 299 dbSNP
rs1226609989 303 dbSNP
rs1184290108 312 dbSNP
rs558083691 317 dbSNP
rs1364127933 324 dbSNP
rs1452851793 329 dbSNP
rs1415605347 338 dbSNP
rs1158196541 342 dbSNP
rs962094238 352 dbSNP
rs1383158693 354 dbSNP
rs980238221 356 dbSNP
rs972723542 361 dbSNP
rs1436818112 363 dbSNP
rs920881502 373 dbSNP
rs577888035 375 dbSNP
rs145887553 378 dbSNP
rs1256302004 384 dbSNP
rs991619601 386 dbSNP
rs916102018 390 dbSNP
rs973252968 391 dbSNP
rs1045507176 392 dbSNP
rs1337424532 400 dbSNP
rs919181684 401 dbSNP
rs1233633758 402 dbSNP
rs1354606736 405 dbSNP
rs928959881 406 dbSNP
rs1411906418 407 dbSNP
rs1290799567 408 dbSNP
rs902843793 409 dbSNP
rs116872726 412 dbSNP
rs1393459964 415 dbSNP
rs911586343 417 dbSNP
rs893017026 418 dbSNP
rs1416147243 419 dbSNP
rs371852138 424 dbSNP
rs1470990814 426 dbSNP
rs1049521078 432 dbSNP
rs1278932660 433 dbSNP
rs542309945 434 dbSNP
rs571185602 438 dbSNP
rs1291877791 448 dbSNP
rs1019069358 449 dbSNP
rs1333799529 451 dbSNP
rs562628829 452 dbSNP
rs936157229 457 dbSNP
rs993479460 460 dbSNP
rs531387350 462 dbSNP
rs1351739640 464 dbSNP
rs1279216669 466 dbSNP
rs1027661800 471 dbSNP
rs1332917430 473 dbSNP
rs1327082325 477 dbSNP
rs1179312764 478 dbSNP
rs1440904765 478 dbSNP
rs1392720055 479 dbSNP
rs952252934 485 dbSNP
rs1402053186 487 dbSNP
rs991755380 490 dbSNP
rs1157659591 492 dbSNP
rs916061224 493 dbSNP
rs545151973 494 dbSNP
rs1254340011 501 dbSNP
rs114939708 504 dbSNP
rs1374898562 512 dbSNP
rs1250889043 514 dbSNP
rs527545558 515 dbSNP
rs190745110 520 dbSNP
rs1447382694 523 dbSNP
rs1014531895 528 dbSNP
rs934408686 529 dbSNP
rs1304347614 532 dbSNP
rs1234164185 533 dbSNP
rs1369492405 536 dbSNP
rs1054025458 538 dbSNP
rs1431880956 542 dbSNP
rs1046131145 543 dbSNP
rs1317123606 555 dbSNP
rs1398649647 557 dbSNP
rs905896920 561 dbSNP
rs368638201 564 dbSNP
rs138501094 567 dbSNP
rs775055380 568 dbSNP
rs529334333 570 dbSNP
rs905581454 579 dbSNP
rs549194360 583 dbSNP
rs569300351 584 dbSNP
rs537976939 589 dbSNP
rs558284334 590 dbSNP
rs571515987 593 dbSNP
rs994009914 597 dbSNP
rs911541662 599 dbSNP
rs182220945 600 dbSNP
rs1027629109 605 dbSNP
rs974450710 606 dbSNP
rs925702233 613 dbSNP
rs1269150978 614 dbSNP
rs1023254412 615 dbSNP
rs936126238 617 dbSNP
rs534210828 618 dbSNP
rs554088230 619 dbSNP
rs1187501142 622 dbSNP
rs924791956 623 dbSNP
rs909448541 624 dbSNP
rs989885348 628 dbSNP
rs1307462219 631 dbSNP
rs1271290586 632 dbSNP
rs184971296 634 dbSNP
rs755346716 635 dbSNP
rs1046020331 636 dbSNP
rs1462415162 638 dbSNP
rs1353807812 639 dbSNP
rs536275762 641 dbSNP
rs12445556 642 dbSNP
rs375205415 659 dbSNP
rs1474386382 660 dbSNP
rs1442170414 666 dbSNP
rs1324799140 675 dbSNP
rs1038387318 679 dbSNP
rs1177900560 691 dbSNP
rs1049212693 692 dbSNP
rs898602350 695 dbSNP
rs191246850 698 dbSNP
rs150096588 705 dbSNP
rs1335897381 706 dbSNP
rs1215971534 709 dbSNP
rs1273025165 714 dbSNP
rs1232271139 721 dbSNP
rs1023387718 723 dbSNP
rs1295608805 726 dbSNP
rs183216204 732 dbSNP
rs2641670 733 dbSNP
rs1443086065 738 dbSNP
rs373508370 738 dbSNP
rs138389273 739 dbSNP
rs188491839 747 dbSNP
rs964698789 754 dbSNP
rs1160141905 757 dbSNP
rs767400624 758 dbSNP
rs750327551 759 dbSNP
rs549331574 760 dbSNP
rs1291514900 765 dbSNP
rs953805434 770 dbSNP
rs548434252 771 dbSNP
rs1212160360 775 dbSNP
rs912235042 776 dbSNP
rs149263675 782 dbSNP
rs943944046 785 dbSNP
rs1428038815 786 dbSNP
rs957095893 791 dbSNP
rs1306536204 792 dbSNP
rs973091862 796 dbSNP
rs531790027 801 dbSNP
rs918410989 806 dbSNP
rs931166758 811 dbSNP
rs551623215 816 dbSNP
rs2646108 817 dbSNP
rs1420736303 818 dbSNP
rs913388133 822 dbSNP
rs534149351 824 dbSNP
rs547667309 825 dbSNP
rs1175658314 827 dbSNP
rs1454782746 828 dbSNP
rs200356956 829 dbSNP
rs1394966042 831 dbSNP
rs887820341 832 dbSNP
rs1430604311 833 dbSNP
rs927580161 834 dbSNP
rs1205348519 836 dbSNP
rs4553617 838 dbSNP
rs1044374115 839 dbSNP
rs748381634 849 dbSNP
rs907226255 850 dbSNP
rs1003107711 851 dbSNP
rs567582397 852 dbSNP
rs1231058197 857 dbSNP
rs1289127686 874 dbSNP
rs1360629966 879 dbSNP
rs1381844335 883 dbSNP
rs1358804819 884 dbSNP
rs534265218 887 dbSNP
rs930057252 888 dbSNP
rs1047185248 892 dbSNP
rs1374941296 897 dbSNP
rs1021751480 901 dbSNP
rs1464038990 911 dbSNP
rs886232446 919 dbSNP
rs1355938244 920 dbSNP
rs1232616864 924 dbSNP
rs1373962304 927 dbSNP
rs1192978176 930 dbSNP
rs536564018 933 dbSNP
rs1270985685 940 dbSNP
rs1189627334 942 dbSNP
rs1485677514 943 dbSNP
rs1279077664 947 dbSNP
rs953773445 951 dbSNP
rs985629856 966 dbSNP
rs1019266209 967 dbSNP
rs556085729 968 dbSNP
rs1318538469 969 dbSNP
rs972665939 970 dbSNP
rs1295289906 975 dbSNP
rs575998936 976 dbSNP
rs1415686812 983 dbSNP
rs1354895300 993 dbSNP
rs1218175925 1006 dbSNP
rs369113622 1021 dbSNP
rs779875046 1022 dbSNP
rs1019250779 1026 dbSNP
rs983929653 1027 dbSNP
rs900435959 1028 dbSNP
rs1166644720 1030 dbSNP
rs1475356269 1036 dbSNP
rs1256169944 1040 dbSNP
rs144497434 1045 dbSNP
rs1032670146 1047 dbSNP
rs957065337 1048 dbSNP
rs1195171825 1050 dbSNP
rs1315823515 1051 dbSNP
rs1274889502 1052 dbSNP
rs928649378 1060 dbSNP
rs1334498767 1061 dbSNP
rs988519987 1068 dbSNP
rs747040912 1072 dbSNP
rs138072957 1073 dbSNP
rs113178212 1074 dbSNP
rs1344309715 1076 dbSNP
rs981650056 1077 dbSNP
rs927475091 1079 dbSNP
rs1314121916 1080 dbSNP
rs541194434 1081 dbSNP
rs4783099 1082 dbSNP
rs1414048848 1083 dbSNP
rs1291410376 1085 dbSNP
rs1011802617 1096 dbSNP
rs193142282 1097 dbSNP
rs929982160 1099 dbSNP
rs1363936214 1100 dbSNP
rs1177926984 1102 dbSNP
rs1456417583 1104 dbSNP
rs1254622700 1110 dbSNP
rs1047556881 1115 dbSNP
rs868264795 1116 dbSNP
rs1306027451 1117 dbSNP
rs1316497623 1118 dbSNP
rs17773634 1128 dbSNP
rs1351472192 1136 dbSNP
rs1282509074 1138 dbSNP
rs944514927 1139 dbSNP
rs1486060374 1141 dbSNP
rs1238588721 1150 dbSNP
rs183536085 1151 dbSNP
rs1256089083 1152 dbSNP
rs900370034 1161 dbSNP
rs996091700 1165 dbSNP
rs1032931799 1177 dbSNP
rs377480575 1178 dbSNP
rs1009916545 1180 dbSNP
rs543920282 1184 dbSNP
rs1385011004 1189 dbSNP
rs143677810 1192 dbSNP
rs147213353 1193 dbSNP
rs565071260 1198 dbSNP
rs527793333 1199 dbSNP
rs1034517928 1202 dbSNP
rs762518593 1204 dbSNP
rs916399316 1205 dbSNP
rs547555624 1209 dbSNP
rs563817742 1210 dbSNP
rs1442853790 1211 dbSNP
rs1365926122 1212 dbSNP
rs768305521 1214 dbSNP
rs1272330131 1216 dbSNP
rs928678201 1219 dbSNP
rs530415264 1220 dbSNP
rs574182585 1223 dbSNP
rs1053505290 1225 dbSNP
rs913248562 1226 dbSNP
rs1174169748 1229 dbSNP
rs1305956538 1233 dbSNP
rs550255657 1239 dbSNP
rs1422778423 1243 dbSNP
rs982823593 1247 dbSNP
rs1262668630 1257 dbSNP
rs1191794046 1259 dbSNP
rs912578390 1260 dbSNP
rs1281214426 1262 dbSNP
rs1276597031 1267 dbSNP
rs1311005488 1269 dbSNP
rs944127593 1278 dbSNP
rs889951286 1280 dbSNP
rs761352559 1281 dbSNP
rs921724366 1291 dbSNP
rs1339143803 1298 dbSNP
rs1277110751 1302 dbSNP
rs1041217686 1309 dbSNP
rs140646311 1311 dbSNP
rs993942420 1313 dbSNP
rs1232626142 1314 dbSNP
rs1446684738 1315 dbSNP
rs1357320764 1321 dbSNP
rs1172456152 1323 dbSNP
rs1410267884 1325 dbSNP
rs1054343434 1328 dbSNP
rs893075191 1337 dbSNP
rs538290558 1338 dbSNP
rs955337438 1339 dbSNP
rs1010591356 1342 dbSNP
rs142229668 1351 dbSNP
rs76372576 1352 dbSNP
rs1482335616 1354 dbSNP
rs1235036345 1355 dbSNP
rs1205846360 1356 dbSNP
rs1171134791 1358 dbSNP
rs1002625455 1359 dbSNP
rs1256630853 1361 dbSNP
rs1216376924 1362 dbSNP
rs7186628 1366 dbSNP
rs1313029772 1367 dbSNP
rs1227184927 1368 dbSNP
rs1376363975 1370 dbSNP
rs1299801029 1373 dbSNP
rs960371681 1374 dbSNP
rs958830758 1381 dbSNP
rs995645743 1382 dbSNP
rs988886165 1394 dbSNP
rs1418797379 1400 dbSNP
rs554763945 1402 dbSNP
rs1027171168 1404 dbSNP
rs1422071922 1417 dbSNP
rs79754226 1418 dbSNP
rs1178271688 1423 dbSNP
rs983471802 1424 dbSNP
rs1236704226 1425 dbSNP
rs1442900489 1431 dbSNP
rs912560869 1436 dbSNP
rs1328164628 1437 dbSNP
rs1371917899 1444 dbSNP
rs1469195519 1445 dbSNP
rs1265609399 1448 dbSNP
rs1220452192 1450 dbSNP
rs978977532 1457 dbSNP
rs965761613 1458 dbSNP
rs911432964 1462 dbSNP
rs1240759481 1463 dbSNP
rs1375996390 1471 dbSNP
rs1307031207 1473 dbSNP
rs1442745705 1475 dbSNP
rs1394958161 1476 dbSNP
rs1293141462 1479 dbSNP
rs1341599913 1486 dbSNP
rs370722525 1487 dbSNP
rs1215637162 1493 dbSNP
rs375517536 1497 dbSNP
rs1272986933 1505 dbSNP
rs1316435223 1508 dbSNP
rs1378939102 1509 dbSNP
rs543697230 1517 dbSNP
rs557002536 1525 dbSNP
rs576367625 1527 dbSNP
rs1041578834 1532 dbSNP
rs1267185107 1537 dbSNP
rs901368237 1542 dbSNP
rs929696617 1543 dbSNP
rs1054270309 1544 dbSNP
rs914435322 1551 dbSNP
rs1046885336 1553 dbSNP
rs1467713306 1559 dbSNP
rs544965744 1564 dbSNP
rs1005187527 1568 dbSNP
rs1300375615 1570 dbSNP
rs3751758 1571 dbSNP
rs560706352 1581 dbSNP
rs1042067474 1583 dbSNP
rs905085782 1584 dbSNP
rs1299039882 1587 dbSNP
rs1167244653 1593 dbSNP
rs1003475988 1594 dbSNP
rs1176077464 1613 dbSNP
rs1462954969 1616 dbSNP
rs1377403581 1618 dbSNP
rs1165311483 1625 dbSNP
rs1430694745 1630 dbSNP
rs906830938 1635 dbSNP
rs867593163 1636 dbSNP
rs1193952941 1640 dbSNP
rs1487668202 1640 dbSNP
rs1260493180 1642 dbSNP
rs1212891855 1646 dbSNP
rs1345690259 1650 dbSNP
rs1255360082 1651 dbSNP
rs1230708915 1656 dbSNP
rs1309056699 1660 dbSNP
rs527730594 1661 dbSNP
rs1461085664 1669 dbSNP
rs956592060 1670 dbSNP
rs988854865 1671 dbSNP
rs1055441026 1691 dbSNP
rs968783391 1697 dbSNP
rs72799585 1698 dbSNP
rs1270126747 1708 dbSNP
rs911236696 1712 dbSNP
rs561531874 1713 dbSNP
rs1170943334 1718 dbSNP
rs1339014750 1719 dbSNP
rs1477311731 1723 dbSNP
rs1372104636 1726 dbSNP
rs187930156 1729 dbSNP
rs192355402 1730 dbSNP
rs951669608 1731 dbSNP
rs1442524850 1739 dbSNP
rs1255317308 1743 dbSNP
rs1334657085 1743 dbSNP
rs1207671730 1744 dbSNP
rs1285977355 1747 dbSNP
rs1004428113 1753 dbSNP
rs116057507 1754 dbSNP
rs1258517625 1762 dbSNP
rs930194027 1767 dbSNP
rs1316242990 1768 dbSNP
rs1295384583 1776 dbSNP
rs1245524742 1781 dbSNP
rs1339957981 1787 dbSNP
rs1332755406 1795 dbSNP
rs1393716009 1797 dbSNP
rs1401437797 1799 dbSNP
rs1047268271 1800 dbSNP
rs965378310 1803 dbSNP
rs975835453 1808 dbSNP
rs114539523 1809 dbSNP
rs958093701 1813 dbSNP
rs1367457185 1818 dbSNP
rs989596457 1820 dbSNP
rs564832236 1824 dbSNP
rs1420857597 1825 dbSNP
rs1238737083 1828 dbSNP
rs552156307 1832 dbSNP
rs1034985393 1841 dbSNP
rs892289101 1858 dbSNP
rs1188618740 1866 dbSNP
rs758574616 1868 dbSNP
rs945874760 1870 dbSNP
rs977333800 1871 dbSNP
rs1471716939 1878 dbSNP
rs1378231488 1880 dbSNP
rs1009323366 1883 dbSNP
rs1397221739 1885 dbSNP
rs1022100218 1886 dbSNP
rs1325112632 1894 dbSNP
rs1401516364 1899 dbSNP
rs968742406 1904 dbSNP
rs374745761 1905 dbSNP
rs565689685 1910 dbSNP
rs1421020966 1911 dbSNP
rs1380764569 1916 dbSNP
rs534697985 1921 dbSNP
rs1055370347 1926 dbSNP
rs964115719 1927 dbSNP
rs554751784 1929 dbSNP
rs977398971 1936 dbSNP
rs532141100 1938 dbSNP
rs1199813053 1942 dbSNP
rs568223642 1960 dbSNP
rs894174829 1962 dbSNP
rs751804492 1963 dbSNP
rs1048133786 1964 dbSNP
rs1350870614 1966 dbSNP
rs1204211542 1969 dbSNP
rs1238700285 1974 dbSNP
rs887248964 1977 dbSNP
rs1275866184 1980 dbSNP
rs1283215898 1981 dbSNP
rs1486391959 1984 dbSNP
rs1004801161 1985 dbSNP
rs1256792864 1989 dbSNP
rs1420926565 1990 dbSNP
rs550635963 1991 dbSNP
rs1019839341 1995 dbSNP
rs1417827978 1999 dbSNP
rs1183636921 2001 dbSNP
rs1364183980 2006 dbSNP
rs901401484 2011 dbSNP
rs536881468 2020 dbSNP
rs149788366 2030 dbSNP
rs1477590467 2035 dbSNP
rs758542584 2037 dbSNP
rs778606506 2037 dbSNP
rs1245131933 2038 dbSNP
rs1196130562 2039 dbSNP
rs1218942071 2039 dbSNP
rs1228277005 2039 dbSNP
rs1262620076 2039 dbSNP
rs1279995139 2039 dbSNP
rs1340560593 2039 dbSNP
rs1350621198 2039 dbSNP
rs1401533598 2039 dbSNP
rs200128084 2039 dbSNP
rs202056163 2039 dbSNP
rs375959407 2039 dbSNP
rs747607696 2039 dbSNP
rs781611022 2039 dbSNP
rs1470611534 2040 dbSNP
rs1028319514 2048 dbSNP
rs1158315526 2057 dbSNP
rs1215522862 2058 dbSNP
rs1397615634 2059 dbSNP
rs941077159 2061 dbSNP
rs1044845269 2062 dbSNP
rs958065854 2062 dbSNP
rs1436721946 2063 dbSNP
rs1314013984 2065 dbSNP
rs926280512 2066 dbSNP
rs1394812582 2069 dbSNP
rs1478299933 2072 dbSNP
rs77864512 2074 dbSNP
rs1336759369 2087 dbSNP
rs1056544236 2088 dbSNP
rs1238500742 2091 dbSNP
rs1306698256 2097 dbSNP
rs1349402969 2098 dbSNP
rs1260435558 2099 dbSNP
rs578186164 2099 dbSNP
rs1318107704 2102 dbSNP
rs1279000258 2107 dbSNP
rs1380725164 2108 dbSNP
rs1482206017 2109 dbSNP
rs1021467974 2115 dbSNP
rs111806030 2118 dbSNP
rs558521405 2121 dbSNP
rs528751617 2125 dbSNP
rs1168818341 2126 dbSNP
rs977676826 2133 dbSNP
rs572157057 2134 dbSNP
rs1181756246 2135 dbSNP
rs938585799 2140 dbSNP
rs1472122019 2141 dbSNP
rs1178237632 2147 dbSNP
rs991400830 2149 dbSNP
rs1236645761 2150 dbSNP
rs1043525751 2152 dbSNP
rs757463691 2157 dbSNP
rs1000233011 2159 dbSNP
rs1256964345 2162 dbSNP
rs1018392900 2163 dbSNP
rs1322968480 2168 dbSNP
rs1312873800 2171 dbSNP
rs1227266496 2172 dbSNP
rs1376836666 2183 dbSNP
rs1311384049 2184 dbSNP
rs115441101 2185 dbSNP
rs1329559776 2188 dbSNP
rs1375955879 2188 dbSNP
rs781409654 2193 dbSNP
rs998156937 2196 dbSNP
rs1030095848 2203 dbSNP
rs1164108861 2205 dbSNP
rs951580665 2208 dbSNP
rs1170192427 2209 dbSNP
rs561261536 2219 dbSNP
rs1179827866 2220 dbSNP
rs1439456801 2222 dbSNP
rs367661684 2230 dbSNP
rs1397636939 2232 dbSNP
rs1175098900 2234 dbSNP
rs1489230450 2236 dbSNP
rs140661163 2238 dbSNP
rs1328867261 2242 dbSNP
rs1489567209 2245 dbSNP
rs1288065542 2252 dbSNP
rs910033359 2255 dbSNP
rs939806990 2265 dbSNP
rs543626977 2267 dbSNP
rs1041595284 2268 dbSNP
rs1302012124 2270 dbSNP
rs901373260 2271 dbSNP
rs1229484278 2272 dbSNP
rs1368519698 2273 dbSNP
rs144428748 2275 dbSNP
rs926361591 2288 dbSNP
rs1028583257 2289 dbSNP
rs893779249 2296 dbSNP
rs1338500940 2297 dbSNP
rs1379027284 2299 dbSNP
rs1010927319 2305 dbSNP
rs1254670733 2307 dbSNP
rs1469950093 2308 dbSNP
rs1194539893 2316 dbSNP
rs1021017343 2323 dbSNP
rs1264756087 2325 dbSNP
rs1217215968 2326 dbSNP
rs1352829451 2327 dbSNP
rs967178849 2328 dbSNP
rs183863751 2337 dbSNP
rs188147556 2339 dbSNP
rs146630545 2340 dbSNP
rs1298836392 2341 dbSNP
rs9933521 2343 dbSNP
rs528119972 2344 dbSNP
rs1383353467 2349 dbSNP
rs1168911203 2352 dbSNP
rs991330680 2353 dbSNP
rs1466866031 2354 dbSNP
rs1377491495 2356 dbSNP
rs1174880344 2366 dbSNP
rs1479281618 2367 dbSNP
rs915842104 2368 dbSNP
rs1487676108 2369 dbSNP
rs1039282367 2371 dbSNP
rs1397179152 2373 dbSNP
rs899890126 2375 dbSNP
rs1255233598 2376 dbSNP
rs1201562441 2381 dbSNP
rs952357894 2390 dbSNP
rs16974880 2391 dbSNP
rs761438320 2393 dbSNP
rs1029651663 2397 dbSNP
rs939756403 2401 dbSNP
rs1364853915 2407 dbSNP
rs568027132 2415 dbSNP
rs1017233110 2418 dbSNP
rs373127705 2419 dbSNP
rs1401937604 2420 dbSNP
rs1170961101 2423 dbSNP
rs1477201540 2426 dbSNP
rs922723816 2428 dbSNP
rs1295678680 2429 dbSNP
rs1370908541 2434 dbSNP
rs932815401 2449 dbSNP
rs1424375709 2454 dbSNP
rs1255428089 2458 dbSNP
rs1201471618 2464 dbSNP
rs1339689413 2465 dbSNP
rs1258938592 2467 dbSNP
rs1216745295 2470 dbSNP
rs1049977654 2471 dbSNP
rs537170638 2478 dbSNP
rs1335282606 2482 dbSNP
rs1011186034 2484 dbSNP
rs1265141773 2485 dbSNP
rs960472652 2488 dbSNP
rs1449381320 2491 dbSNP
rs1487546386 2496 dbSNP
rs1042769264 2500 dbSNP
rs1409048484 2503 dbSNP
rs192768991 2507 dbSNP
rs1393662256 2510 dbSNP
rs902547431 2511 dbSNP
rs992339776 2513 dbSNP
rs913566017 2517 dbSNP
rs1384471938 2522 dbSNP
rs570632661 2525 dbSNP
rs1206908298 2526 dbSNP
rs1004035607 2528 dbSNP
rs1035117667 2531 dbSNP
rs539348114 2533 dbSNP
rs1436245701 2534 dbSNP
rs1477754029 2535 dbSNP
rs979074081 2536 dbSNP
rs959836309 2537 dbSNP
rs552880119 2538 dbSNP
rs1022776534 2542 dbSNP
rs566977742 2545 dbSNP
rs1420440604 2546 dbSNP
rs771633257 2548 dbSNP
rs572094146 2549 dbSNP
rs1163623741 2551 dbSNP
rs952615407 2556 dbSNP
rs1333558711 2557 dbSNP
rs772639569 2558 dbSNP
rs908199423 2562 dbSNP
rs548203908 2573 dbSNP
rs143404268 2574 dbSNP
rs1380869689 2579 dbSNP
rs922361339 2585 dbSNP
rs1468411165 2592 dbSNP
rs1359378504 2594 dbSNP
rs934073051 2599 dbSNP
rs1295108058 2600 dbSNP
rs867822176 2606 dbSNP
rs1049906380 2608 dbSNP
rs1355840965 2610 dbSNP
rs1285936069 2641 dbSNP
rs556686949 2645 dbSNP
rs946944676 2648 dbSNP
rs8939 2652 dbSNP
rs902476303 2653 dbSNP
rs1344299621 2662 dbSNP
rs1004183556 2666 dbSNP
rs1401344343 2678 dbSNP
rs1003558731 2679 dbSNP
rs1315492477 2686 dbSNP
rs543907787 2688 dbSNP
rs1056928649 2689 dbSNP
rs563722760 2690 dbSNP
rs1016951178 2697 dbSNP
rs895216615 2702 dbSNP
rs1398721459 2704 dbSNP
rs1012311619 2705 dbSNP
rs148181046 2707 dbSNP
rs1033832547 2709 dbSNP
rs1195883983 2713 dbSNP
rs1488030452 2714 dbSNP
rs1478197623 2721 dbSNP
rs1215064446 2726 dbSNP
rs961199582 2729 dbSNP
rs1260307495 2730 dbSNP
rs1214365994 2740 dbSNP
rs546496905 2746 dbSNP
rs952586335 2752 dbSNP
rs1322356130 2756 dbSNP
rs1005840814 2758 dbSNP
rs1219869596 2760 dbSNP
rs140101155 2762 dbSNP
rs1015520081 2767 dbSNP
rs979042894 2768 dbSNP
rs924962945 2770 dbSNP
rs1412104587 2773 dbSNP
rs1404107640 2776 dbSNP
rs1420459751 2778 dbSNP
rs1478187989 2779 dbSNP
rs1418947278 2783 dbSNP
rs1185269818 2784 dbSNP
rs184881371 2785 dbSNP
rs975089609 2786 dbSNP
rs923127141 2794 dbSNP
rs1460268010 2799 dbSNP
rs2485 2802 dbSNP
rs1200211522 2804 dbSNP
rs1314641761 2810 dbSNP
rs1271736542 2814 dbSNP
rs1029358031 2818 dbSNP
rs1047605129 2823 dbSNP
rs1381205610 2825 dbSNP
rs953765914 2826 dbSNP
rs985243156 2829 dbSNP
rs1380393755 2833 dbSNP
rs940107798 2842 dbSNP
rs1447223744 2843 dbSNP
rs1354190568 2856 dbSNP
rs1038352262 2858 dbSNP
rs1300817882 2867 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions BT474
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1395167. RNA binding protein: AGO. Condition:BT474 AGO HITS-CLIP Replicate 2 ...

- Pillai MM; Gillen AE; Yamamoto TM; Kline E; et al., 2014, Breast cancer research and treatment.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gcggcccgagggGCCCc 5'
                      |||| 
Target 5' ------------CGGGa 3'
 		1 - 5
2 
miRNA  3' gcggcccGAGGGGCCcc 5'
                 | || | |  
Target 5' aagaucaCGCCACUG-- 3'
 		26 - 40
Article - Pillai MM; Gillen AE; Yamamoto TM; Kline E; et al.
- Breast cancer research and treatment, 2014
miRNAs regulate the expression of genes in both normal physiology and disease. While miRNAs have been demonstrated to play a pivotal role in aspects of cancer biology, these reports have generally focused on the regulation of single genes. Such single-gene approaches have significant limitations, relying on miRNA expression levels and heuristic predictions of mRNA-binding sites. This results in only circumstantial evidence of miRNA-target interaction and typically leads to large numbers of false positive predictions. Here, we used a genome-wide approach (high-throughput sequencing of RNA isolated by crosslinking immunoprecipitation, HITS-CLIP) to define direct miRNA-mRNA interactions in three breast cancer subtypes (estrogen receptor positive, Her2 amplified, and triple negative). Focusing on steroid receptor signaling, we identified two novel regulators of the ER pathway (miR-9-5p and miR-193a/b-3p), which together target multiple genes involved in ER signaling. Moreover, this approach enabled the definition of miR-9-5p as a global regulator of steroid receptor signaling in breast cancer. We show that miRNA targets and networks defined by HITS-CLIP under physiologic conditions are predictive of patient outcomes and provide global insight into miRNA regulation in breast cancer.
LinkOut: [PMID: 24906430]
CLIP-seq Support 1 for dataset GSM1395167
Method / RBP HITS-CLIP / AGO
Cell line / Condition BT474 / BT474 AGO HITS-CLIP Replicate 2
Location of target site ENST00000262424.5 | 3UTR | CGGGAGGCAGAGCUUGCAGUGAGCCAAGAUCACGCCACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 24906430 / GSE57855
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
119 hsa-miR-4532 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT451366 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT451448 ZNF556 zinc finger protein 556 2 4
MIRT458550 CYP2B6 cytochrome P450 family 2 subfamily B member 6 2 2
MIRT460274 SLC26A2 solute carrier family 26 member 2 2 2
MIRT460365 TXNDC16 thioredoxin domain containing 16 2 4
MIRT460539 TM4SF5 transmembrane 4 L six family member 5 2 2
MIRT463626 YY1 YY1 transcription factor 2 2
MIRT468524 SERTAD2 SERTA domain containing 2 2 4
MIRT469966 PTPRF protein tyrosine phosphatase, receptor type F 2 8
MIRT470076 PTGES2 prostaglandin E synthase 2 2 2
MIRT474926 KCTD20 potassium channel tetramerization domain containing 20 2 2
MIRT479976 CARD10 caspase recruitment domain family member 10 2 2
MIRT485533 GPRIN1 G protein regulated inducer of neurite outgrowth 1 2 2
MIRT485939 ECSIT ECSIT signalling integrator 2 4
MIRT486421 RXRA retinoid X receptor alpha 2 2
MIRT487665 HPCAL1 hippocalcin like 1 2 4
MIRT488113 POU3F1 POU class 3 homeobox 1 2 4
MIRT490648 FEM1A fem-1 homolog A 2 2
MIRT491313 LRFN1 leucine rich repeat and fibronectin type III domain containing 1 2 2
MIRT491345 CPNE5 copine 5 2 2
MIRT492688 PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2 2
MIRT496879 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT499243 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT508211 SLC35E1 solute carrier family 35 member E1 2 2
MIRT532712 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT540807 SLC35F5 solute carrier family 35 member F5 2 2
MIRT563529 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT607723 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT608089 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT618519 SELPLG selectin P ligand 2 2
MIRT624702 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT624769 AKR1D1 aldo-keto reductase family 1 member D1 2 2
MIRT629974 MRPL36 mitochondrial ribosomal protein L36 2 2
MIRT631355 ZFP82 ZFP82 zinc finger protein 2 2
MIRT631425 CDNF cerebral dopamine neurotrophic factor 2 2
MIRT631664 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT631734 SF3B1 splicing factor 3b subunit 1 2 2
MIRT632333 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT632418 SLC30A5 solute carrier family 30 member 5 2 2
MIRT632530 PSMB2 proteasome subunit beta 2 2 2
MIRT633263 LDLR low density lipoprotein receptor 2 2
MIRT634326 SLC43A2 solute carrier family 43 member 2 2 2
MIRT634752 CRCP CGRP receptor component 2 2
MIRT635411 KIAA1614 KIAA1614 2 2
MIRT636280 RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase 2 2
MIRT636290 RAD51L3-RFFL RAD51L3-RFFL readthrough 2 2
MIRT641737 TXNL1 thioredoxin like 1 2 2
MIRT643527 ERAP2 endoplasmic reticulum aminopeptidase 2 2 2
MIRT643554 C11orf70 chromosome 11 open reading frame 70 2 2
MIRT647026 NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 2 2
MIRT647297 RBM43 RNA binding motif protein 43 2 2
MIRT648123 SEMA3E semaphorin 3E 2 4
MIRT648610 TPCN2 two pore segment channel 2 2 2
MIRT648716 IL10RB interleukin 10 receptor subunit beta 2 2
MIRT649424 CDC14B cell division cycle 14B 2 2
MIRT650028 DSG3 desmoglein 3 2 2
MIRT650280 TAS2R5 taste 2 receptor member 5 2 2
MIRT654238 RNF115 ring finger protein 115 2 2
MIRT657031 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT658406 FAM212B family with sequence similarity 212 member B 2 2
MIRT661079 FFAR2 free fatty acid receptor 2 2 2
MIRT661528 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT661875 PDLIM5 PDZ and LIM domain 5 2 2
MIRT662099 ZNF419 zinc finger protein 419 2 2
MIRT663637 HM13 histocompatibility minor 13 2 2
MIRT663702 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663844 TRIM72 tripartite motif containing 72 2 2
MIRT664768 MESDC2 mesoderm development LRP chaperone 2 2
MIRT665480 VSTM4 V-set and transmembrane domain containing 4 2 2
MIRT666532 RNF157 ring finger protein 157 2 2
MIRT668106 GK5 glycerol kinase 5 (putative) 2 2
MIRT669741 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT671009 MOB4 MOB family member 4, phocein 2 2
MIRT671582 SPIRE2 spire type actin nucleation factor 2 2 2
MIRT673260 INO80 INO80 complex subunit 2 2
MIRT673532 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT674713 FAM73A mitoguardin 1 2 2
MIRT675204 ZNF554 zinc finger protein 554 2 2
MIRT676487 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT676704 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT676850 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT676854 RAB3B RAB3B, member RAS oncogene family 2 2
MIRT676914 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT676999 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT677187 PDE12 phosphodiesterase 12 2 2
MIRT677472 SLC7A11 solute carrier family 7 member 11 2 2
MIRT677561 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT677778 FKTN fukutin 2 2
MIRT677895 DCP1A decapping mRNA 1A 2 2
MIRT677995 GATC glutamyl-tRNA amidotransferase subunit C 2 2
MIRT678238 HMGB1 high mobility group box 1 2 4
MIRT678312 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT678436 PDE4C phosphodiesterase 4C 2 2
MIRT678479 RNF222 ring finger protein 222 2 2
MIRT678590 ZNF91 zinc finger protein 91 2 2
MIRT678862 SLC7A14 solute carrier family 7 member 14 2 2
MIRT679240 LRP10 LDL receptor related protein 10 2 2
MIRT679387 WDR92 WD repeat domain 92 2 2
MIRT679500 ZNF106 zinc finger protein 106 2 2
MIRT679580 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT679826 TMEM106B transmembrane protein 106B 2 2
MIRT679859 ZFP30 ZFP30 zinc finger protein 2 2
MIRT680472 C3 complement C3 2 2
MIRT683698 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT684267 PRPF4 pre-mRNA processing factor 4 2 2
MIRT689404 ZNF573 zinc finger protein 573 2 2
MIRT694756 ZNF843 zinc finger protein 843 2 2
MIRT695955 FANCM Fanconi anemia complementation group M 2 2
MIRT696365 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT700681 PPAP2B phospholipid phosphatase 3 2 2
MIRT701214 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT702195 LRRC58 leucine rich repeat containing 58 2 2
MIRT706799 RAI1 retinoic acid induced 1 2 2
MIRT711086 NEUROD2 neuronal differentiation 2 2 2
MIRT715997 RGS12 regulator of G protein signaling 12 2 2
MIRT716399 SEPT5 septin 5 2 2
MIRT718442 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT722159 ARHGAP40 Rho GTPase activating protein 40 2 2
MIRT724960 PTK6 protein tyrosine kinase 6 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4532 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4532 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant High Gallbladder Cancer cell line (GBC-SD, NOZ)
hsa-miR-4532 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4532 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4532 Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4532 Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4532 Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4532 Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer tissue
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4532 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4532 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (mitochondrial RNA)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-4532 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4532 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-4532 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4532 Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4532 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (OVSAHO)

Error report submission