miRTarBase - #MIRT608663


—
pre-miRNA Information
pre-miRNA hsa-mir-4540   
Genomic Coordinates chr9: 36864254 - 36864308
Description Homo sapiens miR-4540 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4540
Sequence 35| UUAGUCCUGCCUGUAGGUUUA |55
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs937122950 4 dbSNP
rs143699849 7 dbSNP
Putative Targets

Gene Information
Gene Symbol ABLIM1   
Synonyms ABLIM, LIMAB1, LIMATIN, abLIM-1
Description actin binding LIM protein 1
Transcript NM_001003407   
Other Transcripts NM_002313 , NM_006720   
Expression
Putative miRNA Targets on ABLIM1
3'UTR of ABLIM1
(miRNA target sites are highlighted)		 
>ABLIM1|NM_001003407|3'UTR
   1 GTCCCACTCGTGAATGGCAATTAGAGAAAGGACTGACAGTGGCGGTGCCCCATAGGATGTCATATTGAGGCCCAAACTTG
  81 ATTGGAGAATTTGCAAACTACCGTCGCTCAGCAACACCAAAAAGAGAAAGTCTGGTTAAAACACCATGAGTCAAATGTCG
 161 GGCCAGCCAACAGTAACACTTGCCAAGAAGCATGGCGTAGAAATTTCTATGTTCCGAAACACAGAGTAGTGTCCACATGT
 241 GAGCTTTTCACATTACCTTATGTATACAACAGGAGCTGCGTTGTTTTCTTCTTTTTCTTTTCCTTTATCTGTTGTCCAAC
 321 AACAGTGCTGACTGTCCGGATAAGAGCTGGCAAGTGCCCTTAGGATGCCGCATGGGAAAAATCGGTTATCATAATTTCAA
 401 AGTATAAATATATTTATTAAGTAGCGCTGCGGCTAAGAAGGAAGAGTGAGGGGTCTGTCCATGGGGTGGCAGTGATTTCA
 481 CACCCGCCTTTCTTGAATGGCTTCGTGTTACTCAGCCGTGCCCTGGCAGGAATGGAACTCCATCAGGGAACAGGGCAGCT
 561 CTGTTTGAATGGGGTGAAAAACAGCAAAATTAATTCTTAGCAAGCTCCTTGTTCTCTACTGTTCACCGGGACCTGGCTGG
 641 CAAATGACTTAGCTATTAGTATATTTAAAAACTGTTCAAAAGCAAAAGAGAAGGAACAGGAATGAAAGGAAACCTTCCCT
 721 TAACTCTTTCTGCTTCCCATAGCAGGTCTGGTTCCTGCTCCCCGCCTAGGACAGGAGCTGTCTGGAGCTCCACCTTTGCA
 801 AAGAAAGGAAAAACACAAATTGCCCCCAGATTGGCCCAGTGGCATGCCATTAGGTGATTTTGCATAGGGGCCATATCATT
 881 CATGGCCAAAAAAAACCAAAAAGCAAAAAACAAAAACAAGTCCCATGTCCTACTGACTCTAGTTCTTCCAGTCGTTATCC
 961 TCTGCTGTCTCTCTGGCATCCTATGAATCAGATCAAGCCCATGCTGTTGTTGGTTTTTAAGGTTTCTTTCAATAATAGGC
1041 TAAGGAAAGACATGTTTTTCTCTTTTAAATCTCTGCAACTCCAAAGTAGACTCCTTCGAACGTATTTAATTTGGCCTTTT
1121 CAGCTTTCTTCTTGCCCAGCTCTGTCGAATTCATGGGTGTGTGTGCACATGTTGGTTTCACTCACCCAGAGTAATTTTGT
1201 GAGCATGCATGTGCTTTTTAATTTCTGCTTGAATGTTTGTCCTGCTGTGTTGCAGCTTCTAAAGACATTGTCACCGAGTG
1281 TGTGTGACTCAAAGATCAAGAGTGAGGCTAAACTGCGACCCCAACATCACTTCCTTCATGGAAAGGTGTTGGCGCTGATG
1361 TAGCTCATGGAAGGATCAGACTGGGAACCACAGAGGAAGGATGAGGTGGGATGTGGAGGTCAGAGCATCTCACGAGAGTC
1441 CCTCAGGCTCTGCAACACTAGATTCGAATATGAGCCTAGGGTTTCCCCAACACGTGCGTGCATATGAAACCACATCATGA
1521 TTCCCGACGTGAGTTAGATGAGGGAGAGTTTGTGTAACTCCACACCCAGGAGGGTAAGCCACTTTATTATCATGCTTTGG
1601 GGCTGTGCTTAAGAATTTAAGCTCTGTTTTAAAGCCGAAGAAGAAAACATTTGAATTTACCTTCATATGCCACTAAGAAC
1681 AAAAGCTCTGAAGTTCTTCCTGCTGGCACCAAATATTAGGATTACAAGCTGTCTCTCTGACACCAGTGGTAAAAAAGCAA
1761 GTAGAATAGTTTCTGAGTCTGTGTTGCAGCCTCTGACACGTGGCTCACCGCTGTCATTTGGGGGATGGAATGAACAGTCA
1841 CTGTTCTATAGCATCCTCCTGTGCTCTTACCTAAGGAATCTAAATTGTCCTAGCCTTCCATTGCTATGCACTGAATGAGG
1921 ACTACTCTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGGATCTACTAACATGTTTAG
2001 CAAATGGCTCTGACAGGGTGGCCATGAGCAGATGAGACCAGCTCTTGCTTGGTTGGAAGCCACACTGCAGTTTGCAGTTT
2081 AGCCTTTGGTGTCTCAGTGGCTTCTTGCTTATTCCATGCTTTTTCTATCCCATCCTCTCTCTGTGCCCTCCTGCAATGGC
2161 AGCCTTGGCACAATGCCTGGGTGTCCTCATCCTTGCTTTACTCTGGAAAGTGTGGGGATGGAGAGGATGGTGCATTTCCA
2241 GTGCTTCCTTACCTGTCAATAACAATGGTGGCCACCTGGGTCCCAGCACTTGGCTGGTGGAGAGATTTTTTTCATTATGG
2321 AGCTAATAAAGGGTCCCTACGTTTTACATTGATTAATGAATTATCACCCAGACATGTGCAGATGAAATGTCAATATAAGA
2401 AAAATCAAGGTATTTGGGAAACATGGGCATAATCAGGTAGTTTTGCTAAAATTCCTCTTCCTTGGTCTACATAAAGAAGA
2481 CATGGGTCTGTCATAGAATGGGGACATTAGACTGAAAACTGGGACAACCCCCTTCCTTATTTTATAGAGACTAGGAGTTA
2561 AGGGGCCTGCCTAAGATTGCAGTGATAAAGAACTGAACCCTAAATCAGCTCCCACTAATGAAACCCTGCTTTCCTTGTAT
2641 CTTTTAAACTCAGTTCTGCATCCAACTTGAGAAGAAAAAAAGCTTCTTTCCATATCAAGTACCATATGAGTTCATTTAAA
2721 CTGCACCTTGCAGAAATGCATTGCCAGAAAGCACCAGTAGCCTCCTATCTGCAAGCAGAGTAGTGCTCTGCTCTGGGGAG
2801 GGGTCATTGGAAACCATAATGCAGAGTGGGCCCCCTACTCCATTTCCCAGCAAAAGGCTCCAGCTGGAGGGATGGGTTGT
2881 GGGGCAACCTGGTTCCTGCTAACTGCCAGATTGAATGTGTGGGCTAGAATGCCTGCACATTTAGTTAAACTGGGCTCAGC
2961 ATGCTTGTCCTCAAAATGTCCATCCTGGTCACAGCACACAAGATGGCTATTGGTCTGCTTTTACCCTACCCTGTACTATA
3041 CATGAAAATTCCAGTTATTAACACACTCAAACTGGTGGAGCTTGTTCACCCTAGGAAGGGGATTGTATATATGGCAGGCT
3121 TCCCTGGTGCCGATGTAAAGGGCTACATTTGGGAACATTTGACTTCCTTGGGACTCTTAAGTGCATAATGATGGCATGAA
3201 GTAAAAGGGGCCTCAATGATGATAGGAAAATCAGTTCTTTTAAAATTTCTTCAAGAAAATCCAGGCTATCACATAGTCTT
3281 TCTGTGTGACTTATTAGGAGATAGGAAGAGCATTGGGAAACTTGCACAGCTAGCTATGCATCTACATTTTGGTTTGGGGT
3361 TAGTTATGAAATGTTCTTAATATGACGTGTTCAATAACTTCACATAAACTTCCTGTTCTCCAAAACCTCAAAGAGATAGA
3441 GTTAATGAGTTGTTGTTTTTTTTTAAATGGGGGTAGTTTTCTATCTGTCATGGGCTCTAGCATCTACTCCGCTACCCAAT
3521 TCTGTCATCTCCAAGCTGAGTTTCCTCTTCTGAGGCAGAGGCTGGAGCAGTTCTTTTTCAGTTCTCATCCTCTCCATCCC
3601 AATCCAGTATATCAATCAACTCTAACTCGGAGACGTCTAGCTGGCAATGTTTCTAAAACTTTCACTGGATTTCTTTAGAC
3681 ATTGAAGCAAACATTTTTTTCTAAGAATTGCTTCTCAGATGATGATATCAAATGTATATGCTTTTGCAAGTTTGAAAAGT
3761 TCAAATTAACCACTTTTGACTAGGTAAGTCTTTCTAAAAACCATTTAAAGCTAACTGGGTCTTAGCATCCTCCTGTGTAT
3841 GGAAGAGACAGGTGACCGCTCCAGGTTGGGTGCTCACAGAACCCTTTTCCTGACTCTCATGGAAGATGGTGGAAGGAAAA
3921 TAGACTGTCTCATCAACCCTCCTGTGTCCTCTGAAGCAATCTCAGTTTTTATTAACCACCTCTTCTGTGTTTCTGGTAGC
4001 TATTTAACCTGTATTTAATCTGTACTTCCTATGCCAGCCTCAATTTTATTTGATTTTTACAATTATTCTCTTCTAACCAA
4081 TGAAGTGTTTGTCAGTATGCCCCAAAGCTTGCTCTTTTGTGCTCCCTTTTGAATAACTTTCTATCCAGAAAAAGAGATTA
4161 TTTGGGACTTGAGATTTGCAGTGATACCAACTTATAGCAATGATGTACTTTAAGGGAACTACCCAACTATGTTGTGATAG
4241 AAGAAAGAGAAACCTTCACTTTGGCATTTTTTTTTAATCACTGTTTATTTTTCTGTTTGCGGCCCAGGAAGCAGTGGGAG
4321 GTGGTGGCAGATATGCTTTGCATATGGATTGTTATGTTTTTATTTGGGCAAGTTTAATCATGGAAAACTCAAAAAGAAGG
4401 GGGGAAATGGTCAGTTTAAGCCAAAAGAAACTTTCTAAACAATGTATAGGTACACAGCAAAATTAAACAAATCCAACAAT
4481 TTCTGAAGCTTAGTGTAATTGAGTGGTGGTTGTTATTCAATAAAATTATTCCCAAAAGTGTTTCTCCTAAGAGTGCAGTT
4561 CCCATGAGTCACTTCCTGAACCCATTGACCAAAGGTGGACAGAGACAATCCTGTAGACCTTGACATTCAGAAAGATGTGA
4641 GCTGCTTACTGATCATATATGCATACGTTTCTTTACAGCAGAGGAAACCATTGTCCACAAAACTGATGTTCTTTTGGGGT
4721 TTTATGTACAGACTTGTCCAATCATGTGTGTGGTTCCTGCGAGTTGCTGATGACTCCGCATTGAAGCTCTCTGAGTTCTT
4801 TGATTTTAAGTTGGGTTTATGGAATTTTTTCAAATGTTGGAAGGTGTGTGGTTCTTCCTGCCCTCCCTCCCCTTTTGGAA
4881 ATATGAAAGCAAATGTTTAGAAGAATTCCTTTTGAAAAGCTGTGTCGTGTTCCCTGTGAAACTGAGCAGGTGTGTGTTGG
4961 CGCGCTAAGTGCCACATGCTTGTGTGTAGAGGAGGAGGTGGCCCTGCCGGCTCCGCGCTGCTGTGCCTGTGATCCCTACC
5041 TGCTCCCCGCTCCTGTTGCCAGCAGCACTCACTGCACTCCTTTGTCATATACTCTGCATCACTGTCATACTCACAACTTC
5121 GTGAATAAAGTTGTGTGCTTTATTCGTAGAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' auuugGAUGUCCGUCCUGAUu 5'
               ||: | | ||||||| 
Target 5' atgcaCTGAATG-AGGACTAc 3'
 1906 - 1925 147.00 -9.40
2 
miRNA  3' auuUGGAUGUCCGUCCUGAUu 5'
             | :|| ||  ||||||: 
Target 5' ggcAATTAGAGAAAGGACTGa 3'
 16 - 36 138.00 -14.20
3 
miRNA  3' auuuGGAUGUCCG----------UCCUGAUu 5'
              |||:| |||          ||||:|| 
Target 5' tcttCCTGCTGGCACCAAATATTAGGATTAc 3'
 1695 - 1725 131.00 -15.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30480697 5 COSMIC
COSN31786186 10 COSMIC
COSN30523700 17 COSMIC
COSN30149587 24 COSMIC
COSN30468390 31 COSMIC
COSN31497926 44 COSMIC
COSN26964552 55 COSMIC
COSN32052913 80 COSMIC
COSN30475725 105 COSMIC
COSN31497559 112 COSMIC
COSN31580667 205 COSMIC
COSN20435015 216 COSMIC
COSN16743803 238 COSMIC
COSN28633341 243 COSMIC
COSN31480912 288 COSMIC
COSN21472389 330 COSMIC
COSN28056791 486 COSMIC
COSN22066956 627 COSMIC
COSN20092228 628 COSMIC
COSN22986631 757 COSMIC
COSN22876299 1050 COSMIC
COSN8919043 1052 COSMIC
COSN25813231 1316 COSMIC
COSN1112769 1726 COSMIC
COSN28092095 1746 COSMIC
COSN20107594 1930 COSMIC
COSN28586436 1962 COSMIC
COSN8530229 2089 COSMIC
COSN6057432 2265 COSMIC
COSN16760402 2408 COSMIC
COSN19046905 3342 COSMIC
COSN21403121 3447 COSMIC
COSN29604978 3455 COSMIC
COSN25794061 3464 COSMIC
COSN24238897 3579 COSMIC
COSN20692056 3951 COSMIC
COSN24620590 4036 COSMIC
COSN8149633 4248 COSMIC
COSN20107591 4267 COSMIC
COSN10060255 4720 COSMIC
COSN1472115 4893 COSMIC
rs4751906 1239 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs79725027 3 dbSNP
rs371635584 4 dbSNP
rs1400101017 6 dbSNP
rs758370980 7 dbSNP
rs556239056 9 dbSNP
rs181763007 10 dbSNP
rs754739018 17 dbSNP
rs970186198 20 dbSNP
rs750589056 33 dbSNP
rs767661626 34 dbSNP
rs761938664 40 dbSNP
rs1191085607 41 dbSNP
rs376834163 43 dbSNP
rs753280388 44 dbSNP
rs1259698080 46 dbSNP
rs1279991196 47 dbSNP
rs1213587945 48 dbSNP
rs915859304 48 dbSNP
rs984819606 50 dbSNP
rs1487002493 62 dbSNP
rs558922160 68 dbSNP
rs912488306 70 dbSNP
rs144797705 72 dbSNP
rs954881113 75 dbSNP
rs1423493958 77 dbSNP
rs993609153 78 dbSNP
rs1472608912 87 dbSNP
rs966152887 94 dbSNP
rs1360039787 98 dbSNP
rs535526854 99 dbSNP
rs116278808 102 dbSNP
rs1008351787 103 dbSNP
rs1425391553 105 dbSNP
rs1256588330 108 dbSNP
rs1208073487 114 dbSNP
rs889548598 117 dbSNP
rs1272913339 119 dbSNP
rs749858149 123 dbSNP
rs780634111 133 dbSNP
rs1308414199 138 dbSNP
rs1011280080 142 dbSNP
rs968822693 144 dbSNP
rs1021707673 146 dbSNP
rs1223989711 159 dbSNP
rs893039457 160 dbSNP
rs1013117840 164 dbSNP
rs1450742194 172 dbSNP
rs149419975 178 dbSNP
rs1245388271 179 dbSNP
rs747100903 186 dbSNP
rs1210707898 192 dbSNP
rs1036368870 193 dbSNP
rs934578255 196 dbSNP
rs7919465 209 dbSNP
rs1437907955 212 dbSNP
rs1045572400 215 dbSNP
rs1220020493 216 dbSNP
rs1265099780 224 dbSNP
rs948780968 233 dbSNP
rs1046765765 237 dbSNP
rs112726690 238 dbSNP
rs112346723 239 dbSNP
rs1057139 243 dbSNP
rs1039404886 279 dbSNP
rs919498948 280 dbSNP
rs972263868 282 dbSNP
rs1355001599 286 dbSNP
rs531236888 286 dbSNP
rs1274619515 288 dbSNP
rs879736626 288 dbSNP
rs376537977 311 dbSNP
rs987122540 313 dbSNP
rs377052963 320 dbSNP
rs1456866395 322 dbSNP
rs923843665 325 dbSNP
rs1243865551 330 dbSNP
rs569995789 337 dbSNP
rs79672630 338 dbSNP
rs548338608 339 dbSNP
rs1011644878 340 dbSNP
rs1161161135 344 dbSNP
rs765122538 350 dbSNP
rs185144991 365 dbSNP
rs1339391855 369 dbSNP
rs181359735 370 dbSNP
rs907127231 372 dbSNP
rs1217616923 379 dbSNP
rs1257890970 382 dbSNP
rs1316410675 383 dbSNP
rs1368884863 395 dbSNP
rs1045970111 400 dbSNP
rs547499059 402 dbSNP
rs1185425457 406 dbSNP
rs1243909912 410 dbSNP
rs1003451682 411 dbSNP
rs1249824874 411 dbSNP
rs527541249 412 dbSNP
rs10978 420 dbSNP
rs563940685 421 dbSNP
rs1025839251 424 dbSNP
rs41293060 425 dbSNP
rs575491521 426 dbSNP
rs760840887 430 dbSNP
rs1399052563 432 dbSNP
rs1358713018 443 dbSNP
rs1006553967 450 dbSNP
rs972044606 455 dbSNP
rs1344997488 458 dbSNP
rs1465495154 468 dbSNP
rs1199242743 469 dbSNP
rs1340405756 470 dbSNP
rs1300516259 485 dbSNP
rs944948915 486 dbSNP
rs1261257300 488 dbSNP
rs150283420 489 dbSNP
rs986686194 505 dbSNP
rs774489726 511 dbSNP
rs1320988487 513 dbSNP
rs935144195 517 dbSNP
rs554862103 518 dbSNP
rs1418508055 520 dbSNP
rs989893091 521 dbSNP
rs772169221 529 dbSNP
rs541489220 543 dbSNP
rs1366978892 549 dbSNP
rs1407159515 554 dbSNP
rs74160408 555 dbSNP
rs1330855870 556 dbSNP
rs947384259 568 dbSNP
rs914544479 569 dbSNP
rs991574669 571 dbSNP
rs1031308039 572 dbSNP
rs1284166799 573 dbSNP
rs928703018 574 dbSNP
rs998556374 590 dbSNP
rs1266453625 596 dbSNP
rs971303184 618 dbSNP
rs115007772 619 dbSNP
rs879567739 620 dbSNP
rs1438544409 626 dbSNP
rs1156240386 627 dbSNP
rs1013153672 628 dbSNP
rs1458133747 632 dbSNP
rs1292560757 655 dbSNP
rs1390494394 664 dbSNP
rs1385417805 666 dbSNP
rs534733206 672 dbSNP
rs962355045 672 dbSNP
rs1240045209 674 dbSNP
rs1307254233 675 dbSNP
rs1361637233 677 dbSNP
rs1017934183 691 dbSNP
rs1265030561 709 dbSNP
rs1354030166 717 dbSNP
rs1197261479 721 dbSNP
rs1049370447 723 dbSNP
rs188606528 739 dbSNP
rs1269883420 742 dbSNP
rs1176667715 744 dbSNP
rs1204681869 757 dbSNP
rs1244499379 758 dbSNP
rs374543329 761 dbSNP
rs1051266769 763 dbSNP
rs759867313 764 dbSNP
rs944732820 766 dbSNP
rs902321215 767 dbSNP
rs1043673541 768 dbSNP
rs946578952 775 dbSNP
rs141835986 778 dbSNP
rs774558721 794 dbSNP
rs183849893 798 dbSNP
rs1396638293 800 dbSNP
rs912116825 803 dbSNP
rs1320080186 806 dbSNP
rs916498869 807 dbSNP
rs1050670614 819 dbSNP
rs1258515217 820 dbSNP
rs1428025467 823 dbSNP
rs1196698709 828 dbSNP
rs138330657 829 dbSNP
rs932243188 834 dbSNP
rs1483295590 842 dbSNP
rs915374590 847 dbSNP
rs1307088256 854 dbSNP
rs1180716790 862 dbSNP
rs1057143 863 dbSNP
rs1057144 864 dbSNP
rs1424845981 865 dbSNP
rs386747843 865 dbSNP
rs879592970 865 dbSNP
rs1308390285 871 dbSNP
rs1169197749 873 dbSNP
rs147057118 875 dbSNP
rs1466628294 882 dbSNP
rs1302392794 883 dbSNP
rs1377060621 884 dbSNP
rs547440191 888 dbSNP
rs532477878 889 dbSNP
rs1174188643 893 dbSNP
rs533170270 895 dbSNP
rs1253782007 896 dbSNP
rs1430065444 896 dbSNP
rs974208330 896 dbSNP
rs1181775853 903 dbSNP
rs962964334 910 dbSNP
rs977069281 916 dbSNP
rs971117421 928 dbSNP
rs1205698051 929 dbSNP
rs1191880687 931 dbSNP
rs191311014 932 dbSNP
rs1012794658 937 dbSNP
rs958879533 938 dbSNP
rs776551084 949 dbSNP
rs552000699 953 dbSNP
rs1029429454 954 dbSNP
rs1323709631 957 dbSNP
rs999649630 961 dbSNP
rs1368006630 963 dbSNP
rs902352190 967 dbSNP
rs1299040205 980 dbSNP
rs897895608 983 dbSNP
rs530814282 984 dbSNP
rs1287125055 992 dbSNP
rs768949267 994 dbSNP
rs747195192 999 dbSNP
rs1224243404 1002 dbSNP
rs1226245012 1006 dbSNP
rs1010737722 1007 dbSNP
rs1193264014 1010 dbSNP
rs1351975657 1012 dbSNP
rs563470239 1016 dbSNP
rs1432718917 1023 dbSNP
rs1447026674 1030 dbSNP
rs1441640785 1036 dbSNP
rs1159392497 1038 dbSNP
rs542123500 1039 dbSNP
rs1357196537 1046 dbSNP
rs1418148065 1049 dbSNP
rs574326566 1051 dbSNP
rs1336161257 1052 dbSNP
rs746512742 1053 dbSNP
rs1350272424 1062 dbSNP
rs1470223582 1075 dbSNP
rs1435436687 1078 dbSNP
rs1406982626 1086 dbSNP
rs141671745 1088 dbSNP
rs371867374 1097 dbSNP
rs1307981521 1098 dbSNP
rs1350822379 1100 dbSNP
rs779609213 1101 dbSNP
rs367650650 1102 dbSNP
rs577055064 1116 dbSNP
rs775839785 1117 dbSNP
rs188787972 1127 dbSNP
rs1177938796 1134 dbSNP
rs1459531444 1136 dbSNP
rs907162614 1146 dbSNP
rs932219167 1147 dbSNP
rs772367050 1150 dbSNP
rs1437849385 1153 dbSNP
rs915512750 1154 dbSNP
rs537277755 1163 dbSNP
rs1045818299 1165 dbSNP
rs1053956219 1169 dbSNP
rs553391703 1175 dbSNP
rs1414716807 1190 dbSNP
rs1404562245 1195 dbSNP
rs1162498202 1205 dbSNP
rs1402189301 1209 dbSNP
rs4751906 1239 dbSNP
rs1374057935 1240 dbSNP
rs918661124 1245 dbSNP
rs111585103 1248 dbSNP
rs147815893 1254 dbSNP
rs1206320980 1258 dbSNP
rs971574292 1261 dbSNP
rs1320427175 1269 dbSNP
rs916886222 1270 dbSNP
rs1330526109 1271 dbSNP
rs1284585568 1273 dbSNP
rs143135232 1275 dbSNP
rs1257928899 1276 dbSNP
rs986088860 1291 dbSNP
rs1436153514 1292 dbSNP
rs958644817 1296 dbSNP
rs1027549948 1300 dbSNP
rs1189637397 1308 dbSNP
rs547427960 1310 dbSNP
rs538745515 1316 dbSNP
rs1472629884 1331 dbSNP
rs1029706159 1338 dbSNP
rs1425569269 1341 dbSNP
rs961824795 1344 dbSNP
rs376324625 1353 dbSNP
rs750136374 1367 dbSNP
rs34610844 1371 dbSNP
rs1397955074 1378 dbSNP
rs966484706 1379 dbSNP
rs1008896730 1388 dbSNP
rs1358041982 1389 dbSNP
rs1022040691 1390 dbSNP
rs1455723252 1393 dbSNP
rs890545405 1397 dbSNP
rs1028986512 1401 dbSNP
rs185523529 1411 dbSNP
rs1404956839 1413 dbSNP
rs894042372 1418 dbSNP
rs1412142372 1424 dbSNP
rs1279469976 1428 dbSNP
rs551939255 1433 dbSNP
rs1033608505 1434 dbSNP
rs1054071585 1435 dbSNP
rs1003829666 1437 dbSNP
rs1202788880 1438 dbSNP
rs1445579268 1441 dbSNP
rs1192747218 1444 dbSNP
rs935584553 1447 dbSNP
rs1478992761 1458 dbSNP
rs906447206 1465 dbSNP
rs757102887 1466 dbSNP
rs530586164 1467 dbSNP
rs1187168873 1489 dbSNP
rs1412228773 1490 dbSNP
rs1299653617 1491 dbSNP
rs3802735 1493 dbSNP
rs1398993122 1494 dbSNP
rs1298041473 1496 dbSNP
rs764139895 1497 dbSNP
rs548139174 1498 dbSNP
rs1344407315 1500 dbSNP
rs1232104189 1504 dbSNP
rs1288239077 1512 dbSNP
rs949821008 1514 dbSNP
rs1488779218 1515 dbSNP
rs374298801 1517 dbSNP
rs1259460288 1518 dbSNP
rs917023068 1519 dbSNP
rs59580984 1523 dbSNP
rs145085954 1525 dbSNP
rs911347004 1526 dbSNP
rs376424850 1528 dbSNP
rs756178615 1529 dbSNP
rs541053335 1536 dbSNP
rs532227693 1542 dbSNP
rs1418751841 1552 dbSNP
rs961937509 1553 dbSNP
rs1156423623 1558 dbSNP
rs1383288169 1575 dbSNP
rs922872129 1581 dbSNP
rs201517657 1594 dbSNP
rs1014677253 1597 dbSNP
rs915013444 1605 dbSNP
rs1311609886 1607 dbSNP
rs1354480726 1613 dbSNP
rs1239727940 1621 dbSNP
rs987745749 1624 dbSNP
rs1259148740 1626 dbSNP
rs954815291 1629 dbSNP
rs1289503047 1633 dbSNP
rs1266389608 1636 dbSNP
rs796946968 1639 dbSNP
rs1238306552 1642 dbSNP
rs1438489173 1659 dbSNP
rs1179261222 1661 dbSNP
rs989195459 1667 dbSNP
rs959194943 1670 dbSNP
rs757670921 1674 dbSNP
rs564937969 1704 dbSNP
rs1033970352 1715 dbSNP
rs996181363 1716 dbSNP
rs1460385716 1717 dbSNP
rs748874997 1725 dbSNP
rs1377788872 1731 dbSNP
rs1446050076 1732 dbSNP
rs1032364195 1742 dbSNP
rs999741904 1745 dbSNP
rs902800677 1746 dbSNP
rs1305120894 1751 dbSNP
rs1342543742 1757 dbSNP
rs1245785782 1760 dbSNP
rs570901536 1763 dbSNP
rs1332382118 1766 dbSNP
rs11815817 1770 dbSNP
rs755820894 1779 dbSNP
rs576513145 1781 dbSNP
rs1258586945 1786 dbSNP
rs897131701 1792 dbSNP
rs1167303922 1798 dbSNP
rs1038427019 1799 dbSNP
rs796226784 1800 dbSNP
rs1424072758 1804 dbSNP
rs889877940 1805 dbSNP
rs895551980 1807 dbSNP
rs1417624617 1808 dbSNP
rs3802734 1809 dbSNP
rs193094691 1810 dbSNP
rs570018453 1812 dbSNP
rs11196743 1816 dbSNP
rs766587338 1822 dbSNP
rs1482645390 1823 dbSNP
rs114519601 1825 dbSNP
rs1396875645 1826 dbSNP
rs1292848013 1833 dbSNP
rs1353361412 1839 dbSNP
rs1230583773 1840 dbSNP
rs1308031265 1842 dbSNP
rs538682118 1843 dbSNP
rs1317293844 1848 dbSNP
rs1202319272 1860 dbSNP
rs907838141 1861 dbSNP
rs1257300076 1870 dbSNP
rs1483264228 1876 dbSNP
rs1199556788 1889 dbSNP
rs1218727536 1890 dbSNP
rs11196742 1900 dbSNP
rs1196362971 1903 dbSNP
rs188773771 1907 dbSNP
rs921803553 1908 dbSNP
rs975209966 1917 dbSNP
rs958113268 1918 dbSNP
rs1370381428 1920 dbSNP
rs1306585211 1924 dbSNP
rs959417812 1928 dbSNP
rs1312503181 1929 dbSNP
rs1032334686 1930 dbSNP
rs59678354 1930 dbSNP
rs1298624481 1931 dbSNP
rs1360986807 1937 dbSNP
rs1212759633 1938 dbSNP
rs1303270271 1941 dbSNP
rs779570784 1942 dbSNP
rs999563935 1948 dbSNP
rs1312273063 1959 dbSNP
rs1355628508 1962 dbSNP
rs1277561675 1964 dbSNP
rs966931470 1966 dbSNP
rs1175905494 1968 dbSNP
rs1264404750 1968 dbSNP
rs149179397 1972 dbSNP
rs1270273093 1974 dbSNP
rs1485717133 1976 dbSNP
rs1185316501 1978 dbSNP
rs1159426924 1980 dbSNP
rs1173157197 1980 dbSNP
rs1240446597 1980 dbSNP
rs1270010838 1980 dbSNP
rs1283068605 1980 dbSNP
rs1286638375 1980 dbSNP
rs1344423206 1980 dbSNP
rs1385391634 1980 dbSNP
rs1393314287 1980 dbSNP
rs1421805588 1980 dbSNP
rs1428305482 1980 dbSNP
rs1433855884 1980 dbSNP
rs201559947 1980 dbSNP
rs540088541 1980 dbSNP
rs549344209 1980 dbSNP
rs58418721 1980 dbSNP
rs59947705 1980 dbSNP
rs878947856 1980 dbSNP
rs1431009563 1981 dbSNP
rs1430780148 1991 dbSNP
rs1025675116 1998 dbSNP
rs1472048017 2014 dbSNP
rs1249103078 2016 dbSNP
rs970560784 2017 dbSNP
rs1013849887 2023 dbSNP
rs868116803 2024 dbSNP
rs1278606943 2041 dbSNP
rs1370802475 2044 dbSNP
rs538342048 2047 dbSNP
rs1229672213 2050 dbSNP
rs1315332218 2052 dbSNP
rs1055299174 2053 dbSNP
rs1213651012 2061 dbSNP
rs182839571 2062 dbSNP
rs993342836 2067 dbSNP
rs1459151942 2069 dbSNP
rs1205380759 2072 dbSNP
rs1480799464 2082 dbSNP
rs1255356993 2084 dbSNP
rs1468838119 2100 dbSNP
rs1207922959 2101 dbSNP
rs10787530 2102 dbSNP
rs898953952 2112 dbSNP
rs1285244606 2118 dbSNP
rs1373992266 2129 dbSNP
rs773628594 2130 dbSNP
rs1402301239 2131 dbSNP
rs940385395 2135 dbSNP
rs529945274 2150 dbSNP
rs770285817 2156 dbSNP
rs1224143502 2159 dbSNP
rs1005503856 2162 dbSNP
rs566012024 2171 dbSNP
rs889898056 2172 dbSNP
rs547727378 2173 dbSNP
rs1049818262 2179 dbSNP
rs933273196 2188 dbSNP
rs1232991998 2189 dbSNP
rs1350131850 2192 dbSNP
rs1291800339 2195 dbSNP
rs998780776 2196 dbSNP
rs369255315 2197 dbSNP
rs1272445172 2202 dbSNP
rs974613729 2211 dbSNP
rs1042664442 2215 dbSNP
rs1212554262 2215 dbSNP
rs945648628 2230 dbSNP
rs1485231081 2252 dbSNP
rs1333338719 2263 dbSNP
rs1374494127 2271 dbSNP
rs894054761 2273 dbSNP
rs114890376 2276 dbSNP
rs115442192 2278 dbSNP
rs386747842 2279 dbSNP
rs766389545 2280 dbSNP
rs926381716 2283 dbSNP
rs981854340 2288 dbSNP
rs1374532679 2290 dbSNP
rs949248139 2297 dbSNP
rs17778547 2303 dbSNP
rs1176553493 2304 dbSNP
rs531473748 2311 dbSNP
rs1432141740 2313 dbSNP
rs971871042 2313 dbSNP
rs371637237 2318 dbSNP
rs1220963429 2319 dbSNP
rs966669686 2321 dbSNP
rs3802733 2326 dbSNP
rs1014214679 2330 dbSNP
rs1064266 2332 dbSNP
rs1447322262 2333 dbSNP
rs1255216382 2334 dbSNP
rs59960244 2339 dbSNP
rs868396855 2340 dbSNP
rs554012180 2341 dbSNP
rs1037442952 2342 dbSNP
rs1204387607 2344 dbSNP
rs901250655 2354 dbSNP
rs1004603953 2355 dbSNP
rs1362883104 2359 dbSNP
rs1383066294 2367 dbSNP
rs777776211 2374 dbSNP
rs1021167117 2378 dbSNP
rs1439217753 2380 dbSNP
rs894085876 2384 dbSNP
rs886083241 2390 dbSNP
rs1288345321 2398 dbSNP
rs752475130 2399 dbSNP
rs1394602393 2405 dbSNP
rs933202194 2413 dbSNP
rs1453293397 2416 dbSNP
rs545316759 2416 dbSNP
rs756086787 2425 dbSNP
rs1451993215 2426 dbSNP
rs1180130876 2427 dbSNP
rs1385793496 2428 dbSNP
rs1363962649 2429 dbSNP
rs936516830 2437 dbSNP
rs115533700 2454 dbSNP
rs556531784 2471 dbSNP
rs1383221557 2476 dbSNP
rs1453973349 2478 dbSNP
rs1367477530 2481 dbSNP
rs540028776 2481 dbSNP
rs1162465946 2485 dbSNP
rs1327115007 2487 dbSNP
rs919001728 2493 dbSNP
rs537946556 2494 dbSNP
rs767457298 2498 dbSNP
rs971903685 2500 dbSNP
rs945444611 2501 dbSNP
rs566623231 2502 dbSNP
rs3802731 2503 dbSNP
rs543259919 2509 dbSNP
rs1277602001 2510 dbSNP
rs1358139019 2513 dbSNP
rs1214283387 2520 dbSNP
rs992205198 2523 dbSNP
rs1200049280 2529 dbSNP
rs1250610820 2532 dbSNP
rs1187835389 2533 dbSNP
rs1418191463 2546 dbSNP
rs1179197693 2557 dbSNP
rs1362446758 2563 dbSNP
rs1476352274 2572 dbSNP
rs909151859 2573 dbSNP
rs986037629 2575 dbSNP
rs146673494 2576 dbSNP
rs1300006438 2578 dbSNP
rs1464553088 2579 dbSNP
rs143239973 2584 dbSNP
rs1327058167 2587 dbSNP
rs115859423 2589 dbSNP
rs1233616409 2601 dbSNP
rs1033960037 2604 dbSNP
rs1332673308 2609 dbSNP
rs974200013 2610 dbSNP
rs962822993 2614 dbSNP
rs1015735431 2615 dbSNP
rs1479998626 2624 dbSNP
rs1004551406 2625 dbSNP
rs1193721704 2628 dbSNP
rs531484078 2634 dbSNP
rs1257764732 2645 dbSNP
rs1485785627 2650 dbSNP
rs547662836 2654 dbSNP
rs886200339 2670 dbSNP
rs1021031460 2676 dbSNP
rs1474539899 2681 dbSNP
rs1173099239 2683 dbSNP
rs1009755401 2685 dbSNP
rs1265044285 2690 dbSNP
rs1166387686 2693 dbSNP
rs893947427 2696 dbSNP
rs1030405162 2699 dbSNP
rs1244243841 2706 dbSNP
rs1361968321 2710 dbSNP
rs1353309014 2714 dbSNP
rs997213006 2722 dbSNP
rs1296157779 2725 dbSNP
rs569082766 2726 dbSNP
rs900402377 2727 dbSNP
rs1038938764 2734 dbSNP
rs1257237727 2736 dbSNP
rs751675419 2738 dbSNP
rs1348201564 2739 dbSNP
rs1209674608 2743 dbSNP
rs139873728 2744 dbSNP
rs1484870529 2754 dbSNP
rs1188809920 2760 dbSNP
rs1046100197 2764 dbSNP
rs1428429685 2773 dbSNP
rs1013658414 2780 dbSNP
rs190171108 2785 dbSNP
rs1362458082 2788 dbSNP
rs1435627884 2790 dbSNP
rs1173195536 2795 dbSNP
rs1373430171 2799 dbSNP
rs1455098507 2807 dbSNP
rs1319737923 2810 dbSNP
rs945444231 2815 dbSNP
rs150865562 2816 dbSNP
rs992551324 2820 dbSNP
rs1291369130 2837 dbSNP
rs773536755 2838 dbSNP
rs1426377677 2843 dbSNP
rs1371026154 2845 dbSNP
rs1385628756 2846 dbSNP
rs17091846 2852 dbSNP
rs45613642 2857 dbSNP
rs1050775533 2864 dbSNP
rs974273591 2871 dbSNP
rs1218459207 2872 dbSNP
rs866730227 2876 dbSNP
rs962936824 2879 dbSNP
rs923166618 2881 dbSNP
rs1454733978 2883 dbSNP
rs1015683243 2903 dbSNP
rs976801798 2907 dbSNP
rs1393564028 2909 dbSNP
rs1195459817 2911 dbSNP
rs1421102829 2921 dbSNP
rs561073825 2926 dbSNP
rs1447589755 2931 dbSNP
rs982948565 2932 dbSNP
rs548820723 2935 dbSNP
rs913998371 2936 dbSNP
rs41293058 2937 dbSNP
rs958193044 2938 dbSNP
rs1223966304 2942 dbSNP
rs1308222076 2954 dbSNP
rs1292925847 2956 dbSNP
rs1207427292 2958 dbSNP
rs777224686 2960 dbSNP
rs900140088 2963 dbSNP
rs1237966699 2967 dbSNP
rs1002777970 2985 dbSNP
rs1017283562 3003 dbSNP
rs560318101 3006 dbSNP
rs1227532962 3009 dbSNP
rs1000749402 3014 dbSNP
rs1167024034 3015 dbSNP
rs186910344 3017 dbSNP
rs903806224 3026 dbSNP
rs1323360969 3028 dbSNP
rs1013223548 3029 dbSNP
rs1442514849 3038 dbSNP
rs1042241420 3039 dbSNP
rs897467932 3040 dbSNP
rs1036079617 3041 dbSNP
rs1406361005 3042 dbSNP
rs774554281 3056 dbSNP
rs1307205780 3058 dbSNP
rs1005888821 3059 dbSNP
rs896550128 3064 dbSNP
rs577960006 3067 dbSNP
rs938113506 3070 dbSNP
rs1439590431 3075 dbSNP
rs1398553314 3078 dbSNP
rs1205487332 3079 dbSNP
rs1168369653 3082 dbSNP
rs572354715 3084 dbSNP
rs1189890059 3092 dbSNP
rs1377139507 3094 dbSNP
rs1038342838 3107 dbSNP
rs771487030 3108 dbSNP
rs1197590121 3118 dbSNP
rs562740118 3122 dbSNP
rs35949502 3125 dbSNP
rs1269816387 3128 dbSNP
rs1057145 3129 dbSNP
rs982897907 3131 dbSNP
rs117542131 3132 dbSNP
rs1436371671 3135 dbSNP
rs1352467177 3147 dbSNP
rs553119711 3152 dbSNP
rs573964305 3153 dbSNP
rs923231658 3156 dbSNP
rs1315244826 3157 dbSNP
rs1356446496 3165 dbSNP
rs1414742418 3174 dbSNP
rs1275787891 3176 dbSNP
rs1196881837 3181 dbSNP
rs7906167 3185 dbSNP
rs1260689820 3186 dbSNP
rs7906164 3188 dbSNP
rs1263109730 3194 dbSNP
rs964824491 3203 dbSNP
rs913863429 3210 dbSNP
rs1340358140 3218 dbSNP
rs1213266015 3220 dbSNP
rs1345757934 3221 dbSNP
rs76140744 3222 dbSNP
rs958144355 3223 dbSNP
rs867970653 3232 dbSNP
rs554048766 3252 dbSNP
rs967938260 3264 dbSNP
rs1020913386 3265 dbSNP
rs1337283969 3273 dbSNP
rs1185470699 3276 dbSNP
rs925347869 3284 dbSNP
rs980988305 3290 dbSNP
rs969940121 3293 dbSNP
rs1025238086 3294 dbSNP
rs538929932 3295 dbSNP
rs1434422973 3297 dbSNP
rs1332591411 3308 dbSNP
rs1328771034 3309 dbSNP
rs770702580 3310 dbSNP
rs1013757682 3312 dbSNP
rs961691666 3314 dbSNP
rs571545890 3324 dbSNP
rs549495970 3327 dbSNP
rs1413833085 3330 dbSNP
rs1236809853 3332 dbSNP
rs896297798 3335 dbSNP
rs1281223868 3337 dbSNP
rs1056704454 3340 dbSNP
rs1174380519 3341 dbSNP
rs1014584219 3346 dbSNP
rs113965423 3351 dbSNP
rs1214924996 3353 dbSNP
rs905322451 3355 dbSNP
rs1038332937 3359 dbSNP
rs748986964 3360 dbSNP
rs941391448 3361 dbSNP
rs1470975967 3366 dbSNP
rs34719815 3372 dbSNP
rs1430277670 3374 dbSNP
rs537813400 3376 dbSNP
rs908561056 3379 dbSNP
rs567174539 3383 dbSNP
rs887557847 3386 dbSNP
rs1171235189 3390 dbSNP
rs1387568554 3391 dbSNP
rs548622314 3392 dbSNP
rs3750820 3393 dbSNP
rs1386552085 3419 dbSNP
rs1443120069 3420 dbSNP
rs922760703 3427 dbSNP
rs1183242117 3430 dbSNP
rs560305889 3432 dbSNP
rs1442364847 3433 dbSNP
rs1241766562 3435 dbSNP
rs976018963 3437 dbSNP
rs142402672 3438 dbSNP
rs756006072 3440 dbSNP
rs1351079179 3446 dbSNP
rs979079482 3455 dbSNP
rs533426757 3458 dbSNP
rs746084884 3458 dbSNP
rs1052466494 3459 dbSNP
rs1020651774 3464 dbSNP
rs1183479299 3465 dbSNP
rs1470679230 3465 dbSNP
rs925411898 3465 dbSNP
rs1279904139 3468 dbSNP
rs1009448350 3469 dbSNP
rs981235322 3472 dbSNP
rs1446938175 3474 dbSNP
rs960917683 3476 dbSNP
rs1385342101 3481 dbSNP
rs1338574195 3482 dbSNP
rs1034853243 3488 dbSNP
rs948254810 3490 dbSNP
rs1406884114 3494 dbSNP
rs1002488948 3497 dbSNP
rs1238131751 3503 dbSNP
rs1286218361 3509 dbSNP
rs905270036 3510 dbSNP
rs755519371 3511 dbSNP
rs1272016597 3512 dbSNP
rs992285474 3515 dbSNP
rs55748348 3519 dbSNP
rs1410366933 3531 dbSNP
rs1005608610 3536 dbSNP
rs1181997369 3551 dbSNP
rs182219175 3556 dbSNP
rs1476484899 3560 dbSNP
rs377507802 3566 dbSNP
rs984438963 3570 dbSNP
rs1185940973 3571 dbSNP
rs1461408283 3577 dbSNP
rs1246876363 3578 dbSNP
rs887068263 3579 dbSNP
rs1367969153 3581 dbSNP
rs1047512341 3583 dbSNP
rs1456406596 3584 dbSNP
rs573929588 3590 dbSNP
rs951773162 3591 dbSNP
rs1306002843 3592 dbSNP
rs934252780 3606 dbSNP
rs1415359778 3607 dbSNP
rs561944819 3614 dbSNP
rs901460263 3615 dbSNP
rs1284432288 3618 dbSNP
rs1227558697 3622 dbSNP
rs77656682 3628 dbSNP
rs942874985 3629 dbSNP
rs926123536 3634 dbSNP
rs41293056 3635 dbSNP
rs371066982 3646 dbSNP
rs1189285274 3651 dbSNP
rs913535728 3656 dbSNP
rs1288378514 3662 dbSNP
rs1428642732 3682 dbSNP
rs1054351920 3684 dbSNP
rs988247919 3689 dbSNP
rs960656221 3693 dbSNP
rs936701538 3695 dbSNP
rs1035374969 3711 dbSNP
rs980666949 3719 dbSNP
rs1166906043 3720 dbSNP
rs1377056209 3726 dbSNP
rs1347210778 3727 dbSNP
rs1319171219 3728 dbSNP
rs1045158622 3733 dbSNP
rs1424481283 3739 dbSNP
rs948176172 3746 dbSNP
rs553987347 3763 dbSNP
rs1376971761 3770 dbSNP
rs538869961 3772 dbSNP
rs1363776190 3776 dbSNP
rs1225732631 3787 dbSNP
rs1305099989 3790 dbSNP
rs969168211 3793 dbSNP
rs577777159 3795 dbSNP
rs1212125717 3796 dbSNP
rs1255735560 3797 dbSNP
rs575739818 3802 dbSNP
rs1383738093 3808 dbSNP
rs1482589353 3815 dbSNP
rs556394816 3818 dbSNP
rs557093005 3825 dbSNP
rs1390033497 3827 dbSNP
rs537754887 3835 dbSNP
rs1397185828 3846 dbSNP
rs1016724936 3856 dbSNP
rs1005557854 3857 dbSNP
rs1175144723 3858 dbSNP
rs1184257533 3861 dbSNP
rs144382633 3870 dbSNP
rs190884948 3873 dbSNP
rs1242392780 3878 dbSNP
rs1025640400 3879 dbSNP
rs1387293739 3882 dbSNP
rs998617296 3883 dbSNP
rs1327321853 3885 dbSNP
rs901412214 3892 dbSNP
rs1375801854 3898 dbSNP
rs11551242 3899 dbSNP
rs554729593 3906 dbSNP
rs951745666 3907 dbSNP
rs572367885 3908 dbSNP
rs974426421 3912 dbSNP
rs1464834334 3915 dbSNP
rs751658524 3923 dbSNP
rs1293660012 3932 dbSNP
rs45596641 3935 dbSNP
rs904653879 3939 dbSNP
rs1043255741 3941 dbSNP
rs780042442 3943 dbSNP
rs754655713 3949 dbSNP
rs1190781441 3950 dbSNP
rs1293304499 3951 dbSNP
rs1420592417 3957 dbSNP
rs1010094149 3970 dbSNP
rs551547665 3971 dbSNP
rs1411239060 3972 dbSNP
rs1212905139 3979 dbSNP
rs1364145638 3985 dbSNP
rs758599510 3994 dbSNP
rs987808925 3995 dbSNP
rs939046081 3996 dbSNP
rs573374748 4002 dbSNP
rs1291363980 4015 dbSNP
rs1000484320 4020 dbSNP
rs74160407 4021 dbSNP
rs1045508350 4023 dbSNP
rs1227074535 4026 dbSNP
rs1305350501 4028 dbSNP
rs1425614039 4030 dbSNP
rs879723427 4032 dbSNP
rs1245255752 4040 dbSNP
rs1481735651 4041 dbSNP
rs144127339 4043 dbSNP
rs1250771340 4046 dbSNP
rs896592157 4048 dbSNP
rs1056442668 4054 dbSNP
rs7917021 4060 dbSNP
rs1429821715 4064 dbSNP
rs1419610750 4066 dbSNP
rs562109185 4067 dbSNP
rs1162077516 4078 dbSNP
rs908010343 4080 dbSNP
rs1479260333 4088 dbSNP
rs1270507545 4092 dbSNP
rs1309074803 4095 dbSNP
rs1350206073 4099 dbSNP
rs1295585903 4112 dbSNP
rs1380508348 4116 dbSNP
rs1227876108 4119 dbSNP
rs1287769981 4122 dbSNP
rs762166949 4141 dbSNP
rs983957872 4145 dbSNP
rs1481911404 4152 dbSNP
rs1190001258 4158 dbSNP
rs865990185 4158 dbSNP
rs930924493 4162 dbSNP
rs540657505 4164 dbSNP
rs185927241 4168 dbSNP
rs1206500620 4176 dbSNP
rs564537370 4178 dbSNP
rs1273785238 4179 dbSNP
rs1222915903 4190 dbSNP
rs965718865 4195 dbSNP
rs1360286294 4200 dbSNP
rs369895331 4205 dbSNP
rs1282522580 4207 dbSNP
rs988526372 4214 dbSNP
rs7916374 4220 dbSNP
rs377273709 4223 dbSNP
rs1340287852 4229 dbSNP
rs1018278440 4231 dbSNP
rs1000026487 4238 dbSNP
rs182582772 4240 dbSNP
rs904811261 4259 dbSNP
rs1207878063 4261 dbSNP
rs1449473622 4262 dbSNP
rs1297035447 4263 dbSNP
rs1388006902 4266 dbSNP
rs1043245881 4271 dbSNP
rs1010434852 4274 dbSNP
rs1175096182 4275 dbSNP
rs1332691799 4276 dbSNP
rs1426252875 4276 dbSNP
rs5788065 4276 dbSNP
rs74582830 4276 dbSNP
rs796679000 4276 dbSNP
rs1467738631 4282 dbSNP
rs1347050971 4294 dbSNP
rs1431005503 4295 dbSNP
rs1435984967 4300 dbSNP
rs892204875 4301 dbSNP
rs1319968575 4314 dbSNP
rs1418326277 4327 dbSNP
rs111614372 4330 dbSNP
rs556096536 4331 dbSNP
rs1236744938 4332 dbSNP
rs761153222 4341 dbSNP
rs544487021 4342 dbSNP
rs927584059 4354 dbSNP
rs138269965 4356 dbSNP
rs886517324 4361 dbSNP
rs1480924402 4362 dbSNP
rs1465286302 4364 dbSNP
rs1242379766 4368 dbSNP
rs1207597586 4372 dbSNP
rs947969599 4380 dbSNP
rs909825491 4391 dbSNP
rs1049723477 4392 dbSNP
rs1199081773 4399 dbSNP
rs1247659775 4405 dbSNP
rs1160963364 4406 dbSNP
rs1321438121 4415 dbSNP
rs930807709 4437 dbSNP
rs773879308 4438 dbSNP
rs1039259644 4443 dbSNP
rs983905660 4444 dbSNP
rs944362645 4451 dbSNP
rs1386487234 4461 dbSNP
rs911523287 4480 dbSNP
rs1316759061 4506 dbSNP
rs988475656 4507 dbSNP
rs951260514 4509 dbSNP
rs1434111701 4510 dbSNP
rs925681186 4515 dbSNP
rs1393435463 4525 dbSNP
rs554923947 4528 dbSNP
rs1265730073 4534 dbSNP
rs1336211018 4562 dbSNP
rs147462091 4564 dbSNP
rs1266302546 4568 dbSNP
rs977202602 4573 dbSNP
rs762655870 4574 dbSNP
rs965499759 4583 dbSNP
rs547090369 4585 dbSNP
rs375301115 4589 dbSNP
rs1182043262 4590 dbSNP
rs959944811 4591 dbSNP
rs1035017838 4592 dbSNP
rs1163899476 4595 dbSNP
rs1390336876 4598 dbSNP
rs1452588713 4600 dbSNP
rs1330658992 4608 dbSNP
rs1004826318 4617 dbSNP
rs143069656 4623 dbSNP
rs1161024081 4625 dbSNP
rs1021915324 4635 dbSNP
rs1419407045 4643 dbSNP
rs1027717474 4647 dbSNP
rs1384554131 4649 dbSNP
rs1181651499 4651 dbSNP
rs1460093020 4661 dbSNP
rs1264319563 4663 dbSNP
rs1245033224 4665 dbSNP
rs557381520 4666 dbSNP
rs191881160 4667 dbSNP
rs1039696502 4676 dbSNP
rs1483550775 4683 dbSNP
rs1485668746 4691 dbSNP
rs1259145361 4694 dbSNP
rs1426038710 4705 dbSNP
rs944982611 4710 dbSNP
rs1367912609 4715 dbSNP
rs117804319 4718 dbSNP
rs1057306354 4726 dbSNP
rs1170645275 4733 dbSNP
rs1315015854 4746 dbSNP
rs1428935307 4752 dbSNP
rs1003694016 4762 dbSNP
rs1404318728 4764 dbSNP
rs1396516130 4767 dbSNP
rs906321025 4769 dbSNP
rs1384432747 4772 dbSNP
rs186220858 4777 dbSNP
rs1338151396 4778 dbSNP
rs1229166312 4780 dbSNP
rs934297658 4781 dbSNP
rs1341005040 4783 dbSNP
rs1382362045 4791 dbSNP
rs1204983098 4795 dbSNP
rs1272901072 4798 dbSNP
rs925706003 4822 dbSNP
rs1201484339 4827 dbSNP
rs1255564297 4838 dbSNP
rs1440714192 4843 dbSNP
rs6646 4845 dbSNP
rs909565266 4846 dbSNP
rs948561083 4848 dbSNP
rs1048275585 4851 dbSNP
rs929912692 4865 dbSNP
rs367611283 4866 dbSNP
rs959975871 4870 dbSNP
rs1015446104 4871 dbSNP
rs1399458261 4873 dbSNP
rs983434231 4880 dbSNP
rs1320637979 4888 dbSNP
rs1364066601 4894 dbSNP
rs976647958 4902 dbSNP
rs965844076 4903 dbSNP
rs1188373725 4908 dbSNP
rs76669575 4919 dbSNP
rs1255983405 4920 dbSNP
rs1343486633 4924 dbSNP
rs1259974431 4926 dbSNP
rs985447469 4927 dbSNP
rs1464634767 4929 dbSNP
rs1186868099 4933 dbSNP
rs1269208721 4935 dbSNP
rs968680412 4940 dbSNP
rs1021656335 4944 dbSNP
rs1175080330 4950 dbSNP
rs1291482577 4954 dbSNP
rs1458724178 4956 dbSNP
rs768611916 4961 dbSNP
rs746971172 4962 dbSNP
rs760808927 4963 dbSNP
rs1036264126 4964 dbSNP
rs138805492 4972 dbSNP
rs1297361773 4974 dbSNP
rs1322098131 4978 dbSNP
rs1053334799 4982 dbSNP
rs934320960 4989 dbSNP
rs904147427 4993 dbSNP
rs1207078292 4997 dbSNP
rs1267522249 5000 dbSNP
rs1043109740 5001 dbSNP
rs906277963 5008 dbSNP
rs1023311873 5009 dbSNP
rs1382427812 5014 dbSNP
rs1182725172 5015 dbSNP
rs531424938 5016 dbSNP
rs1455240667 5017 dbSNP
rs1166285943 5023 dbSNP
rs1350150896 5031 dbSNP
rs1457075910 5033 dbSNP
rs1301074164 5043 dbSNP
rs1011969474 5045 dbSNP
rs181485549 5048 dbSNP
rs1289463998 5049 dbSNP
rs1167239010 5055 dbSNP
rs561099017 5057 dbSNP
rs1222205393 5058 dbSNP
rs929876131 5059 dbSNP
rs897111173 5062 dbSNP
rs1322608907 5064 dbSNP
rs1041259681 5065 dbSNP
rs943916496 5068 dbSNP
rs911073007 5071 dbSNP
rs938493464 5075 dbSNP
rs767772312 5077 dbSNP
rs947458039 5082 dbSNP
rs41293052 5098 dbSNP
rs1183146233 5104 dbSNP
rs546238743 5106 dbSNP
rs530949059 5107 dbSNP
rs1413824063 5112 dbSNP
rs1422912588 5116 dbSNP
rs1478277807 5118 dbSNP
rs754225348 5120 dbSNP
rs117111433 5121 dbSNP
rs920644931 5124 dbSNP
rs753165888 5126 dbSNP
rs1291281066 5137 dbSNP
rs1195696738 5139 dbSNP
rs1379897685 5145 dbSNP
rs964854456 5146 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084077. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' auuugGAUGUCCGUCCUGAUu 5'
               ||: | | ||||||| 
Target 5' augcaCUGAAUG-AGGACUAc 3'
 		1 - 20
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions MCF7
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1395165. RNA binding protein: AGO. Condition:MCF7 AGO HITS-CLIP Replicate 3 ...

- Pillai MM; Gillen AE; Yamamoto TM; Kline E; et al., 2014, Breast cancer research and treatment.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' auuuggauguccgUCCUGAUu 5'
                       ||||||| 
Target 5' -----------ugAGGACUAc 3'
 		1 - 10
Article - Pillai MM; Gillen AE; Yamamoto TM; Kline E; et al.
- Breast cancer research and treatment, 2014
miRNAs regulate the expression of genes in both normal physiology and disease. While miRNAs have been demonstrated to play a pivotal role in aspects of cancer biology, these reports have generally focused on the regulation of single genes. Such single-gene approaches have significant limitations, relying on miRNA expression levels and heuristic predictions of mRNA-binding sites. This results in only circumstantial evidence of miRNA-target interaction and typically leads to large numbers of false positive predictions. Here, we used a genome-wide approach (high-throughput sequencing of RNA isolated by crosslinking immunoprecipitation, HITS-CLIP) to define direct miRNA-mRNA interactions in three breast cancer subtypes (estrogen receptor positive, Her2 amplified, and triple negative). Focusing on steroid receptor signaling, we identified two novel regulators of the ER pathway (miR-9-5p and miR-193a/b-3p), which together target multiple genes involved in ER signaling. Moreover, this approach enabled the definition of miR-9-5p as a global regulator of steroid receptor signaling in breast cancer. We show that miRNA targets and networks defined by HITS-CLIP under physiologic conditions are predictive of patient outcomes and provide global insight into miRNA regulation in breast cancer.
LinkOut: [PMID: 24906430]
CLIP-seq Support 1 for dataset GSM1084077
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_SigmaAb
Location of target site ENST00000392952.3 | 3UTR | AUGCACUGAAUGAGGACUACUCUCGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1395165
Method / RBP HITS-CLIP / AGO
Cell line / Condition MCF7 / MCF7 AGO HITS-CLIP Replicate 3
Location of target site ENST00000392952.3 | 3UTR | UGAGGACUACUCUCGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 24906430 / GSE57855
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1013110
Method / RBP HITS-CLIP  / AGO
Cell line / Condition hMSC / hMSC-replicate-1
Location of target site ENST00000392952.3 | 3UTR | UGAGGACUACUCUCGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 24038734 / GSE41272
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
29 hsa-miR-4540 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT154897 GNAS GNAS complex locus 2 2
MIRT444915 PSG11 pregnancy specific beta-1-glycoprotein 11 2 2
MIRT446718 PSG3 pregnancy specific beta-1-glycoprotein 3 2 2
MIRT464587 UBN2 ubinuclein 2 2 2
MIRT468816 RSRC2 arginine and serine rich coiled-coil 2 2 6
MIRT469397 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT491901 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 2 2
MIRT498959 ORC4 origin recognition complex subunit 4 2 8
MIRT499438 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT506234 PEX13 peroxisomal biogenesis factor 13 2 4
MIRT527911 B3GALT5 beta-1,3-galactosyltransferase 5 2 2
MIRT532624 PHF5A PHD finger protein 5A 2 2
MIRT538103 DDX6 DEAD-box helicase 6 2 2
MIRT549032 CASZ1 castor zinc finger 1 2 2
MIRT559870 ATXN3 ataxin 3 2 2
MIRT575888 Ablim1 actin-binding LIM protein 1 2 4
MIRT608663 ABLIM1 actin binding LIM protein 1 2 5
MIRT616515 C9orf170 chromosome 9 open reading frame 170 2 2
MIRT624063 EID1 EP300 interacting inhibitor of differentiation 1 2 2
MIRT625533 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 2 2
MIRT637169 TMEM50A transmembrane protein 50A 2 2
MIRT639274 KLHL23 kelch like family member 23 2 2
MIRT642924 CCDC90B coiled-coil domain containing 90B 2 2
MIRT649085 FBXO25 F-box protein 25 2 2
MIRT655089 PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2 2
MIRT700888 PER2 period circadian clock 2 2 2
MIRT705966 ACBD5 acyl-CoA binding domain containing 5 2 2
MIRT709418 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT723921 ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif 15 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4540 Topotecan 60699 NSC609699 approved resistant cell line (W1)
hsa-miR-4540 Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-4540 Platinum 23939 resistant tissue (non-small cell lung cancer)

Error report submission