miRTarBase - #MIRT610186


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pre-miRNA Information
pre-miRNA hsa-mir-548t   
Genomic Coordinates chr4: 173268160 - 173268233
Description Homo sapiens miR-548t stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548t-3p
Sequence 46| AAAAACCACAAUUACUUUUGCACCA |70
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 2 4 + 173268206 29233923 MiREDiBase
A-to-I 3 4 + 173268207 29233923 MiREDiBase
A-to-I 4 4 + 173268208 29233923 MiREDiBase
A-to-I 10 4 + 173268214 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs73872515 5 dbSNP
rs1426966747 6 dbSNP
rs1158401109 21 dbSNP
rs943938928 24 dbSNP
Putative Targets

Gene Information
Gene Symbol FAM49A   
Synonyms -
Description family with sequence similarity 49 member A
Transcript NM_030797   
Expression
Putative miRNA Targets on FAM49A
3'UTR of FAM49A
(miRNA target sites are highlighted)		 
>FAM49A|NM_030797|3'UTR
   1 AGCTCTGCTCAAAGAAGAGGATCTATGTGCTGACCTCAGAAGATGTATATGTTTACATAATTTAATACAGATTGATGTTA
  81 ATACTTGTGTATTTACATAACCGTTTCCTTCTTGTCACTGAAATATATGGACCTTAATTTGTATCCTGACTGACTCAACC
 161 CAGCAGAGCATAAATTGACTTGAGAGCCTTACCTTTGATGTCTGAAATGAAACCCCCTTCTCCAAAGGCAAAATTCGGAG
 241 ACTTTGATCTTTGCTACTGGAGTCCTTTAACAACATCTATAACGATAAAAAATTCCTAATTGTTTGTGGTAGTATTTTAA
 321 TTCTAGATGTGTTATCTCTCTGGGAAGTATAGTTTATAGAAACACAAAATATTTGATTTCCTGTGTCGGCTCAGCTACAA
 401 GAAACACAACTGTTATCTTGACAGAGGAAGAGAGGAATCCAAGAAAAATGCATGTGGAGAATTAAACCCAAGTGTTTCGA
 481 ATTCAGCACACCCCCTCTCTGTCCTCAGACTGCAGTCCACACGTGCAACTTTTCTGTTTGCACGTGTTTTATTAATCAGC
 561 ATACTCCTTTTCTGTTTGGATTTATATCCCTCTAATGTTCTCCTTTAATTTCACATGAAAAAAAAATCTCCTGTATTTTT
 641 TTCAGTTAGTGGGAGAGCAGCAGAAATAGATAGATGTGCTGTTGCCACTGGACTGATGAAGGTGGCTGTCTTGGAACTGG
 721 GAGACAGGTCCTCAGAGGTGCACTCAGGCAACAGGACAGCCATCTCTCTGCTTCAGCCCTCTGCCTACAGGGATTAGGGA
 801 AATGGAGCTCTGGCTTTGAAGTTATTTGTGAGTTTAGCAACCTTCCAGTTACCTGCAGAGTTCTGGGTGCACAGCCACCC
 881 CTCATAAGAGCCCTGTTCTCTGAAGACCATTCATATGAGAACAAAGGTCTAGGATACTGCATTAGTTACCAGAAAACTAG
 961 GGGAATTTAGAGGGAAAAAAAATCCATGTTTTCTATTTCCCAGGTTTTTAAAAAGTAGCTCTTCCCCAACCCCGTTGCTA
1041 GCTTGTTGCAATATAAAAGCCCTGGTGCACCTGAATTTACTCCTGGCCTTACTAATGATTCATAATGTGATCTTGAGAAA
1121 TGTGTTTAAGCTTTCTGAGTCTTAACCTCCTTGTCTCTAAAATGGGCAATTAAAACAATCTTCAAGAGCCCTGTAAGGTT
1201 AATGCCGATAAAATGACTGACTCCGCCCTTCTTCCTTAGTACGTAGTATCCAGCAAGCATTTGCCCCACCTTGTCTTGTT
1281 GATGAACAATATTATGAAGCCTGCAGTCATTCTCTCTGTACATCAGAGCTTAGTTCGAATGGAATCATGAAAATCTCTGA
1361 TTCTGACCTCCTAAGGAAAAATGAAACCCAGAGGATGTGGTCATACAGGATGGCTCCCATGTGGGCCTAGAACCCAGGAT
1441 GCTTCACTCTTGACTCCATGCTCTTCCTTTTATACCATGTGGCTGTGAATACATACTATGGGATGGGATTCAACCCTTCT
1521 AAGTAAATCCTCAGTCTGGTCTATATTGTTACTTGCCTGTTTCCACTAGAAGGAGTCACCCAGGCATTTAGTGAATGATA
1601 ATCCTAGAAGTTGAGTCTGAGTACATCAGAGTTTGGCATTATTTGCAACATCCCAGGAATGAGCTATAAGACTCCATTGC
1681 TTTCTGGACTTTAGTGACCAGCTGATCTTCCCTTGGATCCTCCAATAAAGGGGAAAAAATACTTGTCTTATGTTGTTTTA
1761 GCAAGGGAGTTCAGCCAAGTGACAGGAAAGATTCCCTGGTCTGCATCTAAACATTAGTCAACAGAAGGAAAAGGCTCTTT
1841 TCCTTGGAGATTTTCAAGTTGAAAAAGTACAGCTGCTTGGATGGAGTTTCTCTCATCAGAATAGAAATATGCTAGGTGGT
1921 CTTCAAGACCTTTTTGAACCTACAGATTCTAAACCTTAGAGGAAGCCAGAATATGTGATCATACCAGGTGAGGAAAGTTA
2001 GGAGATATTCATCTTAAGAGATATCCTATTTGGCAGTCACATGTTACACTTGAGCAACAATTGTCTAGGCTAGAAATATA
2081 GAACCACACAATATTTATCATCATTGGGTCAATTTCTCCCCCTCTATCAAGTGAGGAGATTAAGGCTTAAAGAAAGGAAA
2161 GGACTTGCCAGCCACCACAGGGCTCATGAGGGGCTTGAACCCATGTCGTGTGTCTCTACCACAGCTGACTCTCAGCTGGC
2241 TAATGGAGAAAATGTGAGGAATTACCTGTCAAATTAGATTGAGCTCAGAGTAAATAGATGAGCACATTTATAACTCTAAA
2321 TTAGACTTTCTATCAAATGGGACCAAACATATGGAAGGGGCTGCTGTCCTGCCTCAATTTAGCCAAGACTTGTCTTGTCT
2401 CAAAGCCAAGACTCAGCAGTACATGGATTCTGAGAAGTCCAGGGTCTGAATTGTTGTCTCTGATTACTGGAAGGACAGGT
2481 TAACTGAATGTCTGTGATCACTAACAGGTGATGGGCTTTGTGCCCACTCCAGAGATATTGTGGGAGACAAATTCTTTTAA
2561 CAGCCTGTCCTCCCGGCATCAGGAGTCATTGAACAATCATGGATTGTTGTGTTTGGGATTTTTTTTTTTTTGGCTTTGTT
2641 TTTGGTTTTTGTGTGTGTGTGTGTGTGCTGCATGCACATGCGTCCAAGACTTACGGGTGGTTTAGGGGAAAGTGCTAGCA
2721 ACAGTGTCAATGTCATTGTTAACTATATTTCATATTTGAGGTCTCATTGTTTTCAAATAAACAGTGTTTTCCATGACTGA
2801 GATATTTATTTTTGGGAAAGCAACGAGGTAAAAATTATGTTTCTCAGATGCACTGCTACTTTGGCGTTATTACTGTGTTC
2881 TCAGAAACTCGTTGTGCACCACTAGGAATTAGTAGTAGAAAAAAAAAAACAATAACAAAAAAAAAAAACAACTGGAAATG
2961 GATGTCTTCACATTAGGGGTGGAGTATTAACAACCAGAAAGAAAGTTTGGATATTACCTTTTAACTACTAGTTAACATCA
3041 TGCTTGATCAACATTTGCTCCTAGTTATCACCATTAAATTAAGACCTTAATGGTAAACTGAGGTTACTGATGCATCATCA
3121 CATTTAAGTAAAAATAATTTCATGTTTTCCCCAAAGAAAAATTAAGCCTCCCAATCTTAGGATCCAATTGTGCAGTAGAA
3201 TTCAGAGACTTCTCATTCAATCTTGTATCCTATGCAGCTACAAATATTTTTTAAATGTTAGTAATAAACATTGGAATTTT
3281 GTCTTAAAGAGTTCAAAACCTTGGAACCCAGTTTTCTCACTACGTCTATAAAGGCCATTACAGACCCAAGGCTGTTTTGC
3361 AGTTTTCATATGTTGTTTGCTGAAGTCATTGTAATTTTTTTTGCCTGCTTTGCCTTTTTTTCTACAGGAGTTTTGAGTGT
3441 GAAATGAAAATTAAAGTTTGGTACATATATTTAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' accacguuuucAUUAACACCAAAAa 5'
                     |: || ||||||| 
Target 5' ttttttggcttTGTTTTTGGTTTTt 3'
 2626 - 2650 150.00 -6.90
2 
miRNA  3' acCACGUUUU-CAUUAACACCAAAaa 5'
            || |||:|  ||   |||||||  
Target 5' gcGTCCAAGACTTACGGGTGGTTTag 3'
 2680 - 2705 143.00 -9.02
3 
miRNA  3' accACGUUUUCAUUAACACCAAAAa 5'
             ||| :|||| |||||  |||| 
Target 5' gttTGCTGAAGTCATTGTAATTTTt 3'
 3375 - 3399 126.00 -9.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30527372 3 COSMIC
COSN26975863 7 COSMIC
COSN30457152 8 COSMIC
COSN30155857 10 COSMIC
COSN30465921 10 COSMIC
COSN30472047 14 COSMIC
COSN28616116 16 COSMIC
COSN30471084 20 COSMIC
COSN26975862 30 COSMIC
COSN31786118 33 COSMIC
COSN26671173 35 COSMIC
COSN30162782 37 COSMIC
COSN30608676 42 COSMIC
COSN31558028 95 COSMIC
COSN28725785 111 COSMIC
COSN31549842 118 COSMIC
COSN30169400 193 COSMIC
COSN26664474 214 COSMIC
COSN9865734 469 COSMIC
COSN27250614 617 COSMIC
COSN28201449 779 COSMIC
COSN18789320 858 COSMIC
COSN26462480 1051 COSMIC
COSN6152841 1131 COSMIC
COSN9114517 1168 COSMIC
COSN7114917 1176 COSMIC
COSN9228863 1207 COSMIC
COSN9865732 1267 COSMIC
COSN23588625 1415 COSMIC
COSN4798885 1568 COSMIC
COSN24823373 1735 COSMIC
COSN9114514 1920 COSMIC
COSN9114513 2087 COSMIC
COSN23749729 2093 COSMIC
COSN1804567 2153 COSMIC
COSN29152758 2474 COSMIC
COSN1804563 2475 COSMIC
COSN24939210 2492 COSMIC
COSN17181650 2576 COSMIC
COSN27536975 2619 COSMIC
COSN23116099 2650 COSMIC
COSN7114911 2682 COSMIC
COSN7114910 2840 COSMIC
COSN16227645 2936 COSMIC
COSN16881299 3093 COSMIC
COSN21216565 3213 COSMIC
COSN15025984 3245 COSMIC
COSN21444209 3441 COSMIC
rs7552 276 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs201324134 3 dbSNP
rs1485470789 5 dbSNP
rs369134296 6 dbSNP
rs765457820 7 dbSNP
rs376587125 9 dbSNP
rs1317568804 10 dbSNP
rs187539517 11 dbSNP
rs1232313509 13 dbSNP
rs1373469349 14 dbSNP
rs372607588 16 dbSNP
rs1381999499 19 dbSNP
rs774146267 23 dbSNP
rs770599023 25 dbSNP
rs1314623349 27 dbSNP
rs1454810894 27 dbSNP
rs1360553315 29 dbSNP
rs368577157 37 dbSNP
rs1432409750 38 dbSNP
rs570496174 39 dbSNP
rs755676885 43 dbSNP
rs747685126 47 dbSNP
rs13404748 51 dbSNP
rs1305781067 65 dbSNP
rs568794036 68 dbSNP
rs924383055 74 dbSNP
rs559615335 82 dbSNP
rs1364283301 86 dbSNP
rs1407093942 87 dbSNP
rs936919823 88 dbSNP
rs1350031915 90 dbSNP
rs1389323308 100 dbSNP
rs1309492296 102 dbSNP
rs920175910 103 dbSNP
rs1045197305 109 dbSNP
rs949519543 114 dbSNP
rs918012448 123 dbSNP
rs542891822 127 dbSNP
rs558546769 128 dbSNP
rs1023831542 129 dbSNP
rs1162011309 131 dbSNP
rs1252293314 132 dbSNP
rs1419123873 141 dbSNP
rs1455365961 144 dbSNP
rs992633199 146 dbSNP
rs1383864000 154 dbSNP
rs1427112154 160 dbSNP
rs1364472077 162 dbSNP
rs929971153 164 dbSNP
rs1354298599 174 dbSNP
rs1181357917 175 dbSNP
rs960839553 192 dbSNP
rs1300081725 200 dbSNP
rs1031390911 209 dbSNP
rs999490355 219 dbSNP
rs1313029163 222 dbSNP
rs28490426 229 dbSNP
rs78495239 236 dbSNP
rs537571322 237 dbSNP
rs900320744 243 dbSNP
rs139923046 247 dbSNP
rs944431425 248 dbSNP
rs190729471 261 dbSNP
rs188384201 262 dbSNP
rs1240717289 264 dbSNP
rs141668569 269 dbSNP
rs930290951 271 dbSNP
rs7552 276 dbSNP
rs1419473468 279 dbSNP
rs1427065868 281 dbSNP
rs767999050 283 dbSNP
rs1355276912 284 dbSNP
rs974306797 288 dbSNP
rs1335051393 292 dbSNP
rs1306042428 293 dbSNP
rs1453538817 299 dbSNP
rs948306301 304 dbSNP
rs1031959812 306 dbSNP
rs1361227993 313 dbSNP
rs916710277 316 dbSNP
rs1297460462 319 dbSNP
rs1322083047 324 dbSNP
rs1222504292 333 dbSNP
rs992350773 335 dbSNP
rs1260921022 336 dbSNP
rs1384490333 338 dbSNP
rs905433624 342 dbSNP
rs1241997587 348 dbSNP
rs1485187366 351 dbSNP
rs1188586856 360 dbSNP
rs1045266185 363 dbSNP
rs1480349839 376 dbSNP
rs1385744827 384 dbSNP
rs1014180099 387 dbSNP
rs896614688 388 dbSNP
rs1418065114 409 dbSNP
rs1397079238 415 dbSNP
rs190112266 416 dbSNP
rs781353218 423 dbSNP
rs1174523673 434 dbSNP
rs147901216 438 dbSNP
rs1290614124 439 dbSNP
rs930069625 454 dbSNP
rs1404150834 477 dbSNP
rs1244774032 478 dbSNP
rs747037538 479 dbSNP
rs919955224 486 dbSNP
rs1314686933 490 dbSNP
rs186132487 491 dbSNP
rs1243253912 492 dbSNP
rs1490280844 495 dbSNP
rs1197759092 504 dbSNP
rs1271260270 505 dbSNP
rs942655827 509 dbSNP
rs1213873729 522 dbSNP
rs1405864626 523 dbSNP
rs1402570708 544 dbSNP
rs774727850 546 dbSNP
rs1349459283 556 dbSNP
rs1361124112 561 dbSNP
rs1423708731 562 dbSNP
rs968014535 563 dbSNP
rs1301078629 564 dbSNP
rs1022281798 573 dbSNP
rs1436744990 578 dbSNP
rs1278650264 584 dbSNP
rs986029520 586 dbSNP
rs954702625 589 dbSNP
rs1285531427 590 dbSNP
rs923125125 594 dbSNP
rs1220631542 597 dbSNP
rs988328113 600 dbSNP
rs569812237 613 dbSNP
rs1344671043 614 dbSNP
rs1273503033 616 dbSNP
rs865952988 617 dbSNP
rs1181328651 619 dbSNP
rs1231434096 622 dbSNP
rs1471176838 623 dbSNP
rs1177874953 625 dbSNP
rs1380773066 626 dbSNP
rs1031992004 627 dbSNP
rs956443263 627 dbSNP
rs1000505120 629 dbSNP
rs1405790975 631 dbSNP
rs1298153744 632 dbSNP
rs76649769 633 dbSNP
rs79084090 633 dbSNP
rs1352437620 635 dbSNP
rs1443683665 650 dbSNP
rs1023845388 660 dbSNP
rs1013836468 663 dbSNP
rs1317831094 664 dbSNP
rs778724533 671 dbSNP
rs996031705 678 dbSNP
rs5007483 679 dbSNP
rs533055432 681 dbSNP
rs1047214814 689 dbSNP
rs1205222786 693 dbSNP
rs1422780097 695 dbSNP
rs1169475987 706 dbSNP
rs1019166060 707 dbSNP
rs1038436320 708 dbSNP
rs1008741052 711 dbSNP
rs1159528074 721 dbSNP
rs563790944 729 dbSNP
rs1047503663 730 dbSNP
rs547036068 731 dbSNP
rs994616324 737 dbSNP
rs911184442 740 dbSNP
rs1372389009 746 dbSNP
rs1050810294 751 dbSNP
rs144678800 763 dbSNP
rs1044101449 764 dbSNP
rs1227074347 765 dbSNP
rs1268790473 766 dbSNP
rs76816458 768 dbSNP
rs1341994992 781 dbSNP
rs1219465732 787 dbSNP
rs1262808336 788 dbSNP
rs10182313 792 dbSNP
rs1209692595 801 dbSNP
rs1056994827 807 dbSNP
rs1192123949 815 dbSNP
rs1440386711 817 dbSNP
rs1276911335 818 dbSNP
rs1476297128 826 dbSNP
rs1170905022 836 dbSNP
rs939532486 842 dbSNP
rs924139575 846 dbSNP
rs1467729548 868 dbSNP
rs956515912 874 dbSNP
rs1216653305 875 dbSNP
rs1316914144 877 dbSNP
rs777669607 880 dbSNP
rs1401035503 883 dbSNP
rs755938738 884 dbSNP
rs1282842350 890 dbSNP
rs140821557 913 dbSNP
rs1278064201 915 dbSNP
rs979111815 926 dbSNP
rs968128483 927 dbSNP
rs574221205 929 dbSNP
rs1023293247 931 dbSNP
rs1194144027 937 dbSNP
rs1267661715 942 dbSNP
rs1479253618 944 dbSNP
rs1201217353 951 dbSNP
rs1014283011 954 dbSNP
rs915220256 957 dbSNP
rs974729787 973 dbSNP
rs1026294055 975 dbSNP
rs752425578 979 dbSNP
rs898633472 983 dbSNP
rs964953856 983 dbSNP
rs994362120 983 dbSNP
rs34999982 986 dbSNP
rs1335212789 987 dbSNP
rs1237008041 994 dbSNP
rs1258837706 995 dbSNP
rs767225282 999 dbSNP
rs1006974196 1002 dbSNP
rs1447540159 1012 dbSNP
rs1009261740 1016 dbSNP
rs563920401 1017 dbSNP
rs1357681717 1019 dbSNP
rs1489814917 1022 dbSNP
rs1211243446 1027 dbSNP
rs1331162828 1031 dbSNP
rs543614969 1033 dbSNP
rs1026174072 1034 dbSNP
rs1382644210 1040 dbSNP
rs994564074 1052 dbSNP
rs1163588855 1053 dbSNP
rs933256199 1055 dbSNP
rs150555071 1059 dbSNP
rs1052752258 1066 dbSNP
rs935172557 1069 dbSNP
rs1309244729 1070 dbSNP
rs1044051369 1073 dbSNP
rs925115161 1082 dbSNP
rs1240766566 1087 dbSNP
rs558282563 1092 dbSNP
rs1356968678 1093 dbSNP
rs1246760839 1094 dbSNP
rs1265615650 1095 dbSNP
rs1480116153 1097 dbSNP
rs1186653776 1098 dbSNP
rs1471542820 1102 dbSNP
rs1457871829 1109 dbSNP
rs1183479926 1110 dbSNP
rs1383952050 1117 dbSNP
rs181447569 1119 dbSNP
rs1204798763 1122 dbSNP
rs1438687650 1136 dbSNP
rs895510489 1137 dbSNP
rs1056710443 1141 dbSNP
rs979185263 1146 dbSNP
rs1197284041 1147 dbSNP
rs10172734 1150 dbSNP
rs1401093239 1153 dbSNP
rs551855859 1162 dbSNP
rs924094290 1175 dbSNP
rs141752407 1180 dbSNP
rs1042552640 1183 dbSNP
rs1025905386 1187 dbSNP
rs946775056 1188 dbSNP
rs915336631 1200 dbSNP
rs962908029 1204 dbSNP
rs535763140 1206 dbSNP
rs1202506150 1207 dbSNP
rs569809592 1210 dbSNP
rs1375870152 1214 dbSNP
rs1484527659 1216 dbSNP
rs1007006719 1218 dbSNP
rs889858502 1221 dbSNP
rs530479568 1222 dbSNP
rs1462920399 1224 dbSNP
rs964741171 1225 dbSNP
rs1395078530 1226 dbSNP
rs1164025155 1232 dbSNP
rs1403042915 1237 dbSNP
rs1030135350 1242 dbSNP
rs556325386 1243 dbSNP
rs750668896 1243 dbSNP
rs1178718646 1245 dbSNP
rs987386067 1248 dbSNP
rs1360990594 1253 dbSNP
rs1380341177 1254 dbSNP
rs950709452 1258 dbSNP
rs115727761 1268 dbSNP
rs935241260 1271 dbSNP
rs903727113 1274 dbSNP
rs994680211 1278 dbSNP
rs1260699142 1284 dbSNP
rs1177199902 1293 dbSNP
rs532265042 1294 dbSNP
rs1211413233 1300 dbSNP
rs1260694120 1303 dbSNP
rs570251503 1309 dbSNP
rs1022718111 1316 dbSNP
rs916347981 1323 dbSNP
rs763571839 1327 dbSNP
rs148476014 1336 dbSNP
rs773563955 1337 dbSNP
rs1427342545 1341 dbSNP
rs527315964 1346 dbSNP
rs1176646018 1354 dbSNP
rs1344553229 1357 dbSNP
rs1417568452 1361 dbSNP
rs1299808649 1363 dbSNP
rs1274296401 1364 dbSNP
rs1035788759 1368 dbSNP
rs1340967552 1371 dbSNP
rs765666650 1373 dbSNP
rs1003776340 1374 dbSNP
rs902787174 1376 dbSNP
rs375604876 1387 dbSNP
rs1319932664 1391 dbSNP
rs1042501106 1393 dbSNP
rs762117648 1397 dbSNP
rs1369059746 1400 dbSNP
rs1219338238 1407 dbSNP
rs1306853832 1407 dbSNP
rs1224527234 1414 dbSNP
rs946890993 1419 dbSNP
rs894019240 1421 dbSNP
rs1220515129 1422 dbSNP
rs1307388746 1425 dbSNP
rs560017739 1429 dbSNP
rs943469932 1447 dbSNP
rs1442769896 1458 dbSNP
rs911872388 1463 dbSNP
rs1292808212 1467 dbSNP
rs1407073088 1469 dbSNP
rs568067733 1471 dbSNP
rs1346447321 1476 dbSNP
rs547839043 1477 dbSNP
rs929173036 1478 dbSNP
rs1378054469 1480 dbSNP
rs1175148362 1483 dbSNP
rs1351280689 1483 dbSNP
rs1455811147 1485 dbSNP
rs1268498865 1487 dbSNP
rs962941133 1501 dbSNP
rs1017136684 1502 dbSNP
rs1242938790 1509 dbSNP
rs1191117519 1517 dbSNP
rs1487825345 1520 dbSNP
rs563152216 1521 dbSNP
rs954325360 1539 dbSNP
rs1029754835 1543 dbSNP
rs1204168670 1545 dbSNP
rs1231234458 1550 dbSNP
rs1459181666 1552 dbSNP
rs1180399923 1557 dbSNP
rs1216540181 1561 dbSNP
rs144649696 1566 dbSNP
rs973357316 1580 dbSNP
rs1488017519 1586 dbSNP
rs768803613 1602 dbSNP
rs1022834108 1618 dbSNP
rs1161259229 1621 dbSNP
rs1236779392 1624 dbSNP
rs1405592188 1627 dbSNP
rs1348322162 1633 dbSNP
rs1397477457 1641 dbSNP
rs956099407 1644 dbSNP
rs1300406501 1645 dbSNP
rs1382709045 1653 dbSNP
rs1446183372 1655 dbSNP
rs1031619698 1657 dbSNP
rs141519598 1660 dbSNP
rs1214181444 1666 dbSNP
rs1256442838 1672 dbSNP
rs544043629 1684 dbSNP
rs960079565 1692 dbSNP
rs1199372861 1696 dbSNP
rs775699249 1698 dbSNP
rs1238653431 1702 dbSNP
rs533558631 1712 dbSNP
rs1289400890 1719 dbSNP
rs1398792644 1727 dbSNP
rs1035335392 1739 dbSNP
rs1358086021 1740 dbSNP
rs1421064805 1740 dbSNP
rs1466676101 1745 dbSNP
rs998936388 1751 dbSNP
rs1404802606 1761 dbSNP
rs1435018701 1769 dbSNP
rs1413251423 1770 dbSNP
rs191215873 1771 dbSNP
rs541516548 1773 dbSNP
rs903799268 1787 dbSNP
rs1043597377 1789 dbSNP
rs572545727 1799 dbSNP
rs894935185 1801 dbSNP
rs4263114 1813 dbSNP
rs1219258214 1818 dbSNP
rs939088443 1821 dbSNP
rs1343034200 1822 dbSNP
rs1198641877 1833 dbSNP
rs1175855585 1837 dbSNP
rs554228852 1838 dbSNP
rs918286703 1849 dbSNP
rs1422212182 1851 dbSNP
rs1021161945 1855 dbSNP
rs1195052836 1858 dbSNP
rs1487966595 1862 dbSNP
rs1203332471 1870 dbSNP
rs1261211125 1874 dbSNP
rs1213279413 1881 dbSNP
rs768593606 1885 dbSNP
rs1464137645 1889 dbSNP
rs541811641 1892 dbSNP
rs893956103 1893 dbSNP
rs1039627551 1907 dbSNP
rs749284561 1909 dbSNP
rs1296742712 1910 dbSNP
rs890542459 1916 dbSNP
rs1051729061 1918 dbSNP
rs1362922882 1926 dbSNP
rs1400825187 1928 dbSNP
rs4240234 1929 dbSNP
rs1207704630 1931 dbSNP
rs575314756 1939 dbSNP
rs973303793 1946 dbSNP
rs13032689 1960 dbSNP
rs1276497030 1966 dbSNP
rs1345653606 1973 dbSNP
rs1215884866 1974 dbSNP
rs1283601150 1977 dbSNP
rs1296133337 1986 dbSNP
rs1489175337 1990 dbSNP
rs1217938946 1992 dbSNP
rs1337766999 2010 dbSNP
rs375566504 2014 dbSNP
rs755991673 2020 dbSNP
rs941950118 2029 dbSNP
rs1266268156 2033 dbSNP
rs915723287 2038 dbSNP
rs1294656369 2043 dbSNP
rs1430901863 2045 dbSNP
rs922754648 2050 dbSNP
rs539280846 2051 dbSNP
rs747893136 2052 dbSNP
rs1470070533 2053 dbSNP
rs1157444286 2058 dbSNP
rs1382535185 2064 dbSNP
rs1414995511 2065 dbSNP
rs959784089 2070 dbSNP
rs371361191 2075 dbSNP
rs1464808420 2081 dbSNP
rs1388538100 2085 dbSNP
rs977172726 2091 dbSNP
rs956301387 2095 dbSNP
rs1031694668 2100 dbSNP
rs1172010050 2108 dbSNP
rs967013281 2109 dbSNP
rs1021277763 2118 dbSNP
rs1307041388 2124 dbSNP
rs1000167149 2125 dbSNP
rs1011086653 2140 dbSNP
rs1264436903 2146 dbSNP
rs1487303441 2152 dbSNP
rs1421551374 2156 dbSNP
rs1267424862 2168 dbSNP
rs958301973 2177 dbSNP
rs1022173620 2179 dbSNP
rs570288388 2180 dbSNP
rs1440652909 2181 dbSNP
rs138506495 2182 dbSNP
rs780994764 2197 dbSNP
rs1255667297 2207 dbSNP
rs1008150533 2208 dbSNP
rs1164097548 2209 dbSNP
rs1003316994 2210 dbSNP
rs1444691498 2218 dbSNP
rs1329162500 2220 dbSNP
rs1379031377 2221 dbSNP
rs890664892 2222 dbSNP
rs1481453290 2226 dbSNP
rs1311729791 2230 dbSNP
rs897841840 2236 dbSNP
rs1246493677 2248 dbSNP
rs186408032 2268 dbSNP
rs993604755 2279 dbSNP
rs1240494756 2283 dbSNP
rs897816305 2290 dbSNP
rs1037717829 2305 dbSNP
rs1254476203 2307 dbSNP
rs941902463 2311 dbSNP
rs181027379 2317 dbSNP
rs1055596438 2320 dbSNP
rs189079330 2329 dbSNP
rs1172926249 2343 dbSNP
rs765955461 2349 dbSNP
rs1274473057 2351 dbSNP
rs1466072040 2354 dbSNP
rs1302232194 2358 dbSNP
rs531208307 2363 dbSNP
rs1376669360 2364 dbSNP
rs928524148 2366 dbSNP
rs796938600 2373 dbSNP
rs1233312758 2376 dbSNP
rs1339446755 2377 dbSNP
rs1216184308 2384 dbSNP
rs1339381250 2388 dbSNP
rs977120222 2391 dbSNP
rs956205250 2392 dbSNP
rs1254790547 2398 dbSNP
rs60444781 2399 dbSNP
rs570370851 2406 dbSNP
rs1262674952 2410 dbSNP
rs1196204320 2414 dbSNP
rs1375971874 2414 dbSNP
rs1332524885 2416 dbSNP
rs144605748 2417 dbSNP
rs1022915680 2419 dbSNP
rs1357388067 2426 dbSNP
rs989778868 2437 dbSNP
rs7578073 2441 dbSNP
rs1359724292 2443 dbSNP
rs1279756348 2445 dbSNP
rs1397718559 2445 dbSNP
rs763999584 2458 dbSNP
rs367740887 2461 dbSNP
rs1034918692 2470 dbSNP
rs1218165250 2475 dbSNP
rs1299738839 2486 dbSNP
rs1314479251 2492 dbSNP
rs1211512833 2499 dbSNP
rs1285748749 2502 dbSNP
rs1487535319 2503 dbSNP
rs1458420576 2505 dbSNP
rs865961781 2507 dbSNP
rs1219044411 2516 dbSNP
rs1003798686 2520 dbSNP
rs896955645 2524 dbSNP
rs1189549430 2538 dbSNP
rs1422900372 2539 dbSNP
rs1434819433 2540 dbSNP
rs1185682788 2548 dbSNP
rs1417660414 2550 dbSNP
rs374183788 2555 dbSNP
rs750962722 2559 dbSNP
rs143648127 2562 dbSNP
rs758260964 2569 dbSNP
rs1177820815 2572 dbSNP
rs576914953 2574 dbSNP
rs137989534 2575 dbSNP
rs1030528247 2581 dbSNP
rs1235625666 2592 dbSNP
rs541590477 2595 dbSNP
rs901435826 2596 dbSNP
rs1351900979 2600 dbSNP
rs1041267363 2611 dbSNP
rs1263232601 2612 dbSNP
rs1488033809 2618 dbSNP
rs72047801 2625 dbSNP
rs1219714185 2626 dbSNP
rs75730706 2631 dbSNP
rs1248518680 2632 dbSNP
rs1263978866 2632 dbSNP
rs35003671 2632 dbSNP
rs57899785 2632 dbSNP
rs878909874 2632 dbSNP
rs879071301 2632 dbSNP
rs1354025928 2633 dbSNP
rs1308124942 2634 dbSNP
rs1446437050 2638 dbSNP
rs1162308413 2644 dbSNP
rs1375159939 2645 dbSNP
rs978852057 2649 dbSNP
rs150241862 2650 dbSNP
rs184331937 2651 dbSNP
rs181325164 2653 dbSNP
rs566361363 2660 dbSNP
rs1280487923 2661 dbSNP
rs1380451038 2668 dbSNP
rs139386835 2668 dbSNP
rs545713034 2668 dbSNP
rs1322367251 2675 dbSNP
rs1198098572 2677 dbSNP
rs897930379 2680 dbSNP
rs1456378805 2681 dbSNP
rs960038038 2682 dbSNP
rs1035355412 2686 dbSNP
rs982011424 2693 dbSNP
rs1179701181 2694 dbSNP
rs15653 2694 dbSNP
rs555725386 2694 dbSNP
rs1005329768 2696 dbSNP
rs1381108985 2697 dbSNP
rs1037665309 2707 dbSNP
rs1330190518 2715 dbSNP
rs888216657 2718 dbSNP
rs1446329817 2723 dbSNP
rs529966948 2730 dbSNP
rs764431701 2742 dbSNP
rs553746013 2745 dbSNP
rs1396731203 2746 dbSNP
rs761009734 2749 dbSNP
rs1199476935 2767 dbSNP
rs1451019716 2792 dbSNP
rs1320145650 2793 dbSNP
rs778648219 2805 dbSNP
rs1197462999 2813 dbSNP
rs1264619828 2820 dbSNP
rs1441592843 2821 dbSNP
rs1056112910 2824 dbSNP
rs1488347096 2825 dbSNP
rs540070740 2829 dbSNP
rs1192568410 2834 dbSNP
rs1420789735 2835 dbSNP
rs1478542810 2838 dbSNP
rs1041734274 2842 dbSNP
rs756973768 2861 dbSNP
rs574524595 2865 dbSNP
rs111385135 2866 dbSNP
rs928432299 2872 dbSNP
rs1043185668 2873 dbSNP
rs1276597853 2880 dbSNP
rs113368823 2890 dbSNP
rs568738021 2894 dbSNP
rs1228283671 2896 dbSNP
rs1270627694 2901 dbSNP
rs1344234561 2903 dbSNP
rs1322181260 2915 dbSNP
rs1383937960 2916 dbSNP
rs905297299 2918 dbSNP
rs1451212099 2919 dbSNP
rs915992128 2923 dbSNP
rs1215409498 2928 dbSNP
rs76537966 2929 dbSNP
rs1260635900 2930 dbSNP
rs1376636088 2930 dbSNP
rs1488949330 2930 dbSNP
rs1477324451 2931 dbSNP
rs1297814335 2932 dbSNP
rs1044214022 2933 dbSNP
rs190373779 2936 dbSNP
rs1172982723 2937 dbSNP
rs1041552977 2938 dbSNP
rs1296538154 2939 dbSNP
rs991554282 2939 dbSNP
rs1382790717 2942 dbSNP
rs1322956342 2944 dbSNP
rs866322874 2945 dbSNP
rs1477826087 2946 dbSNP
rs75512401 2947 dbSNP
rs745884019 2948 dbSNP
rs1266019351 2949 dbSNP
rs1283374295 2949 dbSNP
rs5829554 2949 dbSNP
rs867262849 2949 dbSNP
rs1261927170 2950 dbSNP
rs1195996768 2951 dbSNP
rs928650719 2952 dbSNP
rs552176641 2953 dbSNP
rs945762606 2960 dbSNP
rs1157243109 2961 dbSNP
rs1382611337 2964 dbSNP
rs1454496955 2980 dbSNP
rs914332662 2986 dbSNP
rs753348271 3001 dbSNP
rs1388611088 3007 dbSNP
rs540152550 3011 dbSNP
rs1327763225 3015 dbSNP
rs1371664640 3017 dbSNP
rs1446024445 3025 dbSNP
rs773210552 3027 dbSNP
rs1337353468 3030 dbSNP
rs964048137 3037 dbSNP
rs1239289734 3038 dbSNP
rs188377432 3040 dbSNP
rs1353598707 3042 dbSNP
rs986775795 3052 dbSNP
rs1215023508 3061 dbSNP
rs1274290577 3062 dbSNP
rs1344778609 3063 dbSNP
rs1177387586 3070 dbSNP
rs954997706 3071 dbSNP
rs1420100407 3080 dbSNP
rs1030480183 3084 dbSNP
rs972227479 3089 dbSNP
rs1366965058 3105 dbSNP
rs1028494425 3119 dbSNP
rs368103016 3130 dbSNP
rs1016347993 3140 dbSNP
rs1006344046 3145 dbSNP
rs527871270 3152 dbSNP
rs1277699182 3153 dbSNP
rs1398346541 3160 dbSNP
rs1361068517 3162 dbSNP
rs965453811 3167 dbSNP
rs1398301110 3172 dbSNP
rs1019266161 3173 dbSNP
rs999083975 3174 dbSNP
rs1234811415 3177 dbSNP
rs3088224 3187 dbSNP
rs151116115 3194 dbSNP
rs1197273585 3197 dbSNP
rs531800810 3207 dbSNP
rs1253616638 3210 dbSNP
rs1481139979 3213 dbSNP
rs1011707577 3226 dbSNP
rs1399807454 3232 dbSNP
rs184335153 3241 dbSNP
rs894603539 3244 dbSNP
rs1476895530 3250 dbSNP
rs1003182579 3255 dbSNP
rs1190927842 3263 dbSNP
rs1462251073 3268 dbSNP
rs1302030784 3271 dbSNP
rs1399882607 3281 dbSNP
rs1416209763 3286 dbSNP
rs1475921025 3292 dbSNP
rs758631627 3299 dbSNP
rs1339208777 3309 dbSNP
rs1216286605 3311 dbSNP
rs1186407214 3313 dbSNP
rs1169007977 3319 dbSNP
rs1442202628 3323 dbSNP
rs143841801 3324 dbSNP
rs1233246620 3328 dbSNP
rs1201047141 3331 dbSNP
rs1486888444 3332 dbSNP
rs752006883 3337 dbSNP
rs1262780947 3350 dbSNP
rs1487312477 3350 dbSNP
rs1188374712 3355 dbSNP
rs1041500025 3362 dbSNP
rs938771300 3363 dbSNP
rs11554538 3369 dbSNP
rs928655501 3371 dbSNP
rs1216821345 3378 dbSNP
rs1381442756 3379 dbSNP
rs1436376048 3384 dbSNP
rs1036382729 3391 dbSNP
rs766930424 3403 dbSNP
rs1428288677 3406 dbSNP
rs945876827 3417 dbSNP
rs893012226 3419 dbSNP
rs1362096881 3422 dbSNP
rs1386687625 3422 dbSNP
rs1338474536 3428 dbSNP
rs867495481 3429 dbSNP
rs1350453393 3436 dbSNP
rs1054115702 3455 dbSNP
rs942493615 3461 dbSNP
rs1333180246 3462 dbSNP
rs908468078 3466 dbSNP
rs1190500635 3467 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084044. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep3 HITS-CLIP data was present in GSM1084076. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_SigmaAb HITS-CLIP data was present in GSM1084083. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084044
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep3
Location of target site ENST00000381323.3 | 3UTR | UUGUGUGUGUGUGUGUGUGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084076
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_SigmaAb
Location of target site ENST00000381323.3 | 3UTR | CUUUGUUUUUGGUUUUUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084083
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_SigmaAb
Location of target site ENST00000381323.3 | 3UTR | GUUUUUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
168 hsa-miR-548t-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059365 ANP32E acidic nuclear phosphoprotein 32 family member E 2 2
MIRT072839 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 6
MIRT076945 PCGF2 polycomb group ring finger 2 2 6
MIRT083941 TFAP2C transcription factor AP-2 gamma 2 2
MIRT085401 ETS2 ETS proto-oncogene 2, transcription factor 2 2
MIRT109790 KLHL15 kelch like family member 15 2 2
MIRT114046 AKAP11 A-kinase anchoring protein 11 2 10
MIRT130165 TXNIP thioredoxin interacting protein 2 6
MIRT150013 MIDN midnolin 2 2
MIRT181258 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT205594 NCL nucleolin 2 2
MIRT222253 ACTB actin beta 2 4
MIRT245653 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 4
MIRT250947 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT252497 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT271990 ARF1 ADP ribosylation factor 1 2 4
MIRT280804 RNF11 ring finger protein 11 2 2
MIRT293803 FEM1A fem-1 homolog A 2 2
MIRT318231 RREB1 ras responsive element binding protein 1 2 2
MIRT341455 ATP6V0B ATPase H+ transporting V0 subunit b 2 2
MIRT347413 CEBPG CCAAT/enhancer binding protein gamma 2 4
MIRT351860 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT357983 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT377094 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT407303 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT441564 LMOD3 leiomodin 3 2 2
MIRT442364 ZC3H12C zinc finger CCCH-type containing 12C 2 2
MIRT443228 ARL5B ADP ribosylation factor like GTPase 5B 2 2
MIRT443404 HMX3 H6 family homeobox 3 2 2
MIRT446055 NR5A2 nuclear receptor subfamily 5 group A member 2 2 2
MIRT448277 ZNF652 zinc finger protein 652 2 2
MIRT450822 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT453016 CCDC115 coiled-coil domain containing 115 2 17
MIRT454463 PPP2R2B protein phosphatase 2 regulatory subunit Bbeta 2 2
MIRT456360 CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 2 2
MIRT460007 DNALI1 dynein axonemal light intermediate chain 1 2 2
MIRT463154 ZNF385A zinc finger protein 385A 2 6
MIRT463766 YPEL2 yippee like 2 2 2
MIRT468310 SFT2D2 SFT2 domain containing 2 2 2
MIRT470668 POLR2D RNA polymerase II subunit D 2 4
MIRT478517 CTTN cortactin 2 2
MIRT480507 C11orf57 chromosome 11 open reading frame 57 2 2
MIRT484718 INHBA inhibin beta A subunit 2 12
MIRT485494 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT487302 SLC38A9 solute carrier family 38 member 9 2 2
MIRT487771 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 16
MIRT491876 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT494304 CEP120 centrosomal protein 120 2 2
MIRT495396 TRIM24 tripartite motif containing 24 2 2
MIRT495646 CDK1 cyclin dependent kinase 1 2 2
MIRT496665 TMEM237 transmembrane protein 237 2 2
MIRT496837 ZNF460 zinc finger protein 460 2 2
MIRT498638 CHD4 chromodomain helicase DNA binding protein 4 2 10
MIRT503928 FBXL13 F-box and leucine rich repeat protein 13 2 4
MIRT506063 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT506582 MIER3 MIER family member 3 2 4
MIRT506606 MAT2A methionine adenosyltransferase 2A 2 4
MIRT506844 KIF23 kinesin family member 23 2 6
MIRT508536 RPP14 ribonuclease P/MRP subunit p14 2 4
MIRT509669 ZNF354B zinc finger protein 354B 2 10
MIRT511170 MBNL3 muscleblind like splicing regulator 3 2 6
MIRT512147 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT512831 ID4 inhibitor of DNA binding 4, HLH protein 2 6
MIRT514558 XRCC3 X-ray repair cross complementing 3 2 4
MIRT515856 AJAP1 adherens junctions associated protein 1 2 4
MIRT521848 PNISR PNN interacting serine and arginine rich protein 2 4
MIRT525364 SYNM synemin 2 2
MIRT527120 ARHGAP15 Rho GTPase activating protein 15 2 2
MIRT527271 FBLN2 fibulin 2 2 2
MIRT527439 COL4A3 collagen type IV alpha 3 chain 2 2
MIRT527658 CD300E CD300e molecule 2 2
MIRT528334 TBC1D22B TBC1 domain family member 22B 2 2
MIRT529033 EXOC8 exocyst complex component 8 2 2
MIRT529321 PDE5A phosphodiesterase 5A 2 2
MIRT529677 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT529846 SMTN smoothelin 2 2
MIRT530385 ZNF431 zinc finger protein 431 2 2
MIRT530913 GPR85 G protein-coupled receptor 85 2 2
MIRT531794 KDR kinase insert domain receptor 2 2
MIRT532246 KLF2 Kruppel like factor 2 2 4
MIRT532658 CBX7 chromobox 7 2 2
MIRT533630 TMX3 thioredoxin related transmembrane protein 3 2 2
MIRT534811 RAB33B RAB33B, member RAS oncogene family 2 2
MIRT534975 PSD3 pleckstrin and Sec7 domain containing 3 2 2
MIRT536588 ITPKB inositol-trisphosphate 3-kinase B 2 2
MIRT536779 HNRNPD heterogeneous nuclear ribonucleoprotein D 2 2
MIRT538764 CABLES1 Cdk5 and Abl enzyme substrate 1 2 2
MIRT539294 ANGEL2 angel homolog 2 2 2
MIRT539621 SHISA9 shisa family member 9 2 2
MIRT539651 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT540347 OPHN1 oligophrenin 1 2 2
MIRT540413 PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 2 2
MIRT541396 CDC27 cell division cycle 27 2 2
MIRT542916 HSBP1 heat shock factor binding protein 1 2 2
MIRT544710 EIF5A eukaryotic translation initiation factor 5A 2 4
MIRT544998 MFF mitochondrial fission factor 2 4
MIRT553289 TSPAN3 tetraspanin 3 2 2
MIRT553455 TNRC6C trinucleotide repeat containing 6C 2 2
MIRT553782 TAF13 TATA-box binding protein associated factor 13 2 2
MIRT554656 ROBO1 roundabout guidance receptor 1 2 2
MIRT555104 PURB purine rich element binding protein B 2 2
MIRT557235 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT560861 GAL3ST3 galactose-3-O-sulfotransferase 3 2 2
MIRT561545 SON SON DNA binding protein 2 2
MIRT561554 SLMO2 PRELI domain containing 3B 2 2
MIRT563764 ZNF678 zinc finger protein 678 2 2
MIRT565653 SIX4 SIX homeobox 4 2 2
MIRT568080 CELF2 CUGBP Elav-like family member 2 2 2
MIRT568759 MYBL1 MYB proto-oncogene like 1 2 2
MIRT569078 CADM2 cell adhesion molecule 2 2 2
MIRT569509 THYN1 thymocyte nuclear protein 1 2 2
MIRT571268 CDKN2AIP CDKN2A interacting protein 2 2
MIRT571809 PHF19 PHD finger protein 19 2 2
MIRT572554 DKK3 dickkopf WNT signaling pathway inhibitor 3 2 2
MIRT573782 SLC24A4 solute carrier family 24 member 4 2 4
MIRT576441 Ccdc115 coiled-coil domain containing 115 2 10
MIRT576712 Slc30a3 solute carrier family 30 (zinc transporter), member 3 2 3
MIRT608377 PIWIL2 piwi like RNA-mediated gene silencing 2 2 2
MIRT608484 NKTR natural killer cell triggering receptor 2 6
MIRT610186 FAM49A family with sequence similarity 49 member A 2 2
MIRT611631 EDIL3 EGF like repeats and discoidin domains 3 2 2
MIRT613534 TRA2B transformer 2 beta homolog 2 2
MIRT616221 PTPN11 protein tyrosine phosphatase, non-receptor type 11 2 2
MIRT622370 SALL1 spalt like transcription factor 1 2 2
MIRT624371 CDK12 cyclin dependent kinase 12 2 2
MIRT624995 ZNF665 zinc finger protein 665 2 4
MIRT626875 AP3B1 adaptor related protein complex 3 beta 1 subunit 2 2
MIRT627737 RAP2B RAP2B, member of RAS oncogene family 2 4
MIRT628490 ADAT2 adenosine deaminase, tRNA specific 2 2 2
MIRT633647 PLEKHG7 pleckstrin homology and RhoGEF domain containing G7 2 4
MIRT634028 SLC30A3 solute carrier family 30 member 3 2 3
MIRT635923 GLTSCR2 NOP53 ribosome biogenesis factor 2 2
MIRT638287 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT641959 RNF115 ring finger protein 115 2 2
MIRT643573 CTNNA3 catenin alpha 3 2 2
MIRT645180 NOL9 nucleolar protein 9 2 4
MIRT647497 ZNF639 zinc finger protein 639 2 2
MIRT647682 PCK1 phosphoenolpyruvate carboxykinase 1 2 2
MIRT648422 MYOZ3 myozenin 3 2 2
MIRT650113 ZCCHC9 zinc finger CCHC-type containing 9 2 2
MIRT651076 ZNF518B zinc finger protein 518B 2 4
MIRT651415 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT651456 XKR4 XK related 4 2 2
MIRT653619 SLC30A4 solute carrier family 30 member 4 2 2
MIRT653637 SLC30A1 solute carrier family 30 member 1 2 2
MIRT654896 POU2F1 POU class 2 homeobox 1 2 2
MIRT656483 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT658016 GABRA4 gamma-aminobutyric acid type A receptor alpha4 subunit 2 2
MIRT658041 FZD10 frizzled class receptor 10 2 2
MIRT660093 BTBD3 BTB domain containing 3 2 2
MIRT663923 MAGEF1 MAGE family member F1 2 2
MIRT665882 TGIF2 TGFB induced factor homeobox 2 2 2
MIRT669051 CEP128 centrosomal protein 128 2 2
MIRT669711 AAGAB alpha and gamma adaptin binding protein 2 2
MIRT686812 SNX2 sorting nexin 2 2 4
MIRT689883 SOD2 superoxide dismutase 2 2 2
MIRT693274 GLRX2 glutaredoxin 2 2 4
MIRT697056 BCAR1 BCAR1, Cas family scaffolding protein 2 2
MIRT703297 GID4 GID complex subunit 4 homolog 2 2
MIRT704087 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT707719 CDC6 cell division cycle 6 2 2
MIRT708136 GK5 glycerol kinase 5 (putative) 2 2
MIRT709212 KLHL30 kelch like family member 30 2 2
MIRT710062 RWDD2A RWD domain containing 2A 2 2
MIRT712770 POU6F2 POU class 6 homeobox 2 2 2
MIRT715073 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT715387 TADA3 transcriptional adaptor 3 2 2
MIRT717712 NCKAP1 NCK associated protein 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-548t Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-548t Cisplatin 5460033 NSC119875 approved sensitive cell line (W1)
hsa-mir-548t Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-mir-548t Topotecan 60699 NSC609699 approved sensitive cell line (W1)
hsa-mir-548t Vincristine 5978 approved sensitive cell line (W1)
hsa-miR-548t-3p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (SW480, HCT-116)
hsa-miR-548t-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-548t-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)

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