pre-miRNA Information
pre-miRNA hsa-mir-6818   
Genomic Coordinates chr22: 30007049 - 30007113
Description Homo sapiens miR-6818 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6818-3p
Sequence 44| UUGUCUCUUGUUCCUCACACAG |65
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1325627700 2 dbSNP
rs750902684 3 dbSNP
rs756542190 6 dbSNP
rs1365035732 17 dbSNP
Putative Targets

Gene Information
Gene Symbol MYO1F   
Synonyms -
Description myosin IF
Transcript NM_012335   
Expression
Putative miRNA Targets on MYO1F
3'UTR of MYO1F
(miRNA target sites are highlighted)
>MYO1F|NM_012335|3'UTR
   1 GCTGGGCCCTGGGATACTGCCTTCTCTTTCGCCCGCCTATCTGCCTGCCGGCCTGGTGGGGAGCCAGGCCCTGCCAATGA
  81 GAGCCTCGTTTACCTGGGCTGCAATAGCCTAAAAGTCCAGTCCTTTGGCCTCCAGTCCTGCCCAGGCCCTGGGTCACCAG
 161 GTCACTGCTGCAGCCCCCGCCCCTGGGCCCTGGTCTTCCTCCAACATCACACCTGCTGCCCATTCTCCATTTCTGTGTGT
 241 GTCAAAGGGGACTAACAGCAGAATCTACCTCCCAACTGCCATGTGATTAAGAAATGGGTCTTGAGTCCTGTGCTGTTGGC
 321 AAAGTGCCAGGCACAGTTGGGGAGGGGGGGGTCCTTAACAAGCGTGACTTTGCTCATTCTGTCATCACTAAGGCAATAAA
 401 CCTTTGCCAGGTGAAAGCACGAGTTAACTTACTAAGTGCCCAACAAGGACGATGTTTTCACAGCCCTGTGAGGTAGGAGC
 481 TGTGAAGGACCCCATCTTACAGGTGGAACAATGGAGGTTCAGAGAGGTTCACTGACCCAAGACTGCACAGAGCCATGCCT
 561 TGCATTCATATGTGACCATAAAGCTTGAATTTGTCCCAGTTTGGGCTGGGCGCAGTGGCTCACGCCTGTAATCCCAGCAC
 641 TTTGGGAGGCTGAGGCGGGCAGATCACGTGAGACCAGGAGTTCAAGACCAGCCTGGATAACACAGCAAAACCCTGTTTCT
 721 ACTAAAAATTTAAAAAAG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' gaCACACUCCUUGUUCUCUGuu 5'
            ||||| |  | |:|:|||  
Target 5' ctGTGTGTGTCAAAGGGGACta 3'
233 - 254 116.00 -17.10
2
miRNA  3' gacACACUCCUUGUUCUCUguu 5'
             || ||||  | |||||   
Target 5' caaTG-GAGGTTC-AGAGAggt 3'
509 - 528 113.00 -12.80
3
miRNA  3' gacacacUCCU--UGU-UCUCUGUu 5'
                 | ||  :|| |||| || 
Target 5' ctgacccAAGACTGCACAGAGCCAt 3'
532 - 556 113.00 -5.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN24314865 9 COSMIC
COSN30178083 9 COSMIC
COSN30153804 13 COSMIC
COSN30478814 24 COSMIC
COSN13844848 30 COSMIC
COSN31593704 63 COSMIC
COSN30473880 64 COSMIC
COSN28852783 129 COSMIC
COSN31580746 183 COSMIC
COSN31486195 223 COSMIC
COSN31604471 225 COSMIC
COSN26553843 259 COSMIC
COSN31539239 267 COSMIC
COSN30165506 300 COSMIC
COSN28633042 326 COSMIC
COSN31551700 343 COSMIC
COSN22615073 349 COSMIC
COSN20670517 611 COSMIC
COSN24858039 706 COSMIC
COSN16255217 738 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs753465471 2 dbSNP
rs1271936861 4 dbSNP
rs1431567179 5 dbSNP
rs764689507 6 dbSNP
rs374597578 9 dbSNP
rs752941186 11 dbSNP
rs1365909043 14 dbSNP
rs767959721 20 dbSNP
rs1008693374 21 dbSNP
rs759625300 23 dbSNP
rs953331775 24 dbSNP
rs944922976 25 dbSNP
rs1477394126 29 dbSNP
rs533611108 30 dbSNP
rs763012452 31 dbSNP
rs989344208 32 dbSNP
rs190908621 34 dbSNP
rs200910214 35 dbSNP
rs373721466 36 dbSNP
rs141749665 39 dbSNP
rs1443170003 40 dbSNP
rs1215432426 45 dbSNP
rs1344919720 47 dbSNP
rs1281478744 48 dbSNP
rs771881166 49 dbSNP
rs745692023 50 dbSNP
rs1372055796 51 dbSNP
rs1175712291 57 dbSNP
rs1417681302 58 dbSNP
rs895532930 60 dbSNP
rs1362581750 61 dbSNP
rs1014181318 63 dbSNP
rs897934975 68 dbSNP
rs1412770327 69 dbSNP
rs961550191 69 dbSNP
rs1374602205 76 dbSNP
rs1442517421 78 dbSNP
rs1015510167 81 dbSNP
rs1338413305 86 dbSNP
rs1466774121 87 dbSNP
rs1005833984 88 dbSNP
rs888270674 94 dbSNP
rs372580076 95 dbSNP
rs926774337 101 dbSNP
rs1263118500 107 dbSNP
rs1049199927 117 dbSNP
rs1045265639 120 dbSNP
rs930871056 132 dbSNP
rs575777950 142 dbSNP
rs900514266 158 dbSNP
rs1187344784 164 dbSNP
rs1422035117 168 dbSNP
rs1164801149 174 dbSNP
rs148428772 176 dbSNP
rs944979165 177 dbSNP
rs913512662 178 dbSNP
rs146225868 179 dbSNP
rs1376646745 180 dbSNP
rs987952932 181 dbSNP
rs13346588 186 dbSNP
rs780509524 192 dbSNP
rs1054618 195 dbSNP
rs1336928319 198 dbSNP
rs926100423 201 dbSNP
rs1282173816 210 dbSNP
rs1054619 225 dbSNP
rs141649251 229 dbSNP
rs1216720078 230 dbSNP
rs1280076770 235 dbSNP
rs969746798 239 dbSNP
rs1244100558 240 dbSNP
rs1474420514 247 dbSNP
rs1187754629 249 dbSNP
rs916916833 250 dbSNP
rs1419208183 253 dbSNP
rs1054621 265 dbSNP
rs1476433392 268 dbSNP
rs138505600 270 dbSNP
rs544506974 275 dbSNP
rs1400809007 282 dbSNP
rs575779374 287 dbSNP
rs1054622 291 dbSNP
rs1319846264 297 dbSNP
rs1354697950 301 dbSNP
rs540599977 310 dbSNP
rs769420539 312 dbSNP
rs1293748403 316 dbSNP
rs1054623 326 dbSNP
rs1296654888 328 dbSNP
rs758259822 329 dbSNP
rs952539849 337 dbSNP
rs1278920033 343 dbSNP
rs1424378977 343 dbSNP
rs1028128399 344 dbSNP
rs1172855797 344 dbSNP
rs1286597046 345 dbSNP
rs996268828 345 dbSNP
rs747216890 349 dbSNP
rs186103433 351 dbSNP
rs1009865591 352 dbSNP
rs34276116 352 dbSNP
rs1417699392 354 dbSNP
rs1188687412 358 dbSNP
rs776289673 360 dbSNP
rs772344634 363 dbSNP
rs576916415 364 dbSNP
rs1470178696 367 dbSNP
rs1248052052 372 dbSNP
rs1159851768 376 dbSNP
rs564564792 383 dbSNP
rs1001679021 392 dbSNP
rs1313137834 402 dbSNP
rs555949929 407 dbSNP
rs1053802652 411 dbSNP
rs936229565 413 dbSNP
rs1480699082 417 dbSNP
rs1259470455 420 dbSNP
rs553842062 421 dbSNP
rs533777844 423 dbSNP
rs905635874 432 dbSNP
rs1443019557 438 dbSNP
rs1293823894 439 dbSNP
rs1044505469 444 dbSNP
rs779127127 445 dbSNP
rs568087491 450 dbSNP
rs376979143 451 dbSNP
rs1281343148 475 dbSNP
rs1350459222 476 dbSNP
rs917032442 483 dbSNP
rs1305177832 485 dbSNP
rs1438966546 488 dbSNP
rs1184605726 491 dbSNP
rs992579597 496 dbSNP
rs116789656 506 dbSNP
rs1173842592 510 dbSNP
rs1396565715 511 dbSNP
rs1460268449 515 dbSNP
rs749791892 526 dbSNP
rs1393002100 527 dbSNP
rs984455733 536 dbSNP
rs1333459431 556 dbSNP
rs1323828131 557 dbSNP
rs1368821352 565 dbSNP
rs1440307835 568 dbSNP
rs1459878086 573 dbSNP
rs1394481448 575 dbSNP
rs1164331554 579 dbSNP
rs1474007054 583 dbSNP
rs1036571018 587 dbSNP
rs537662887 595 dbSNP
rs1362392049 608 dbSNP
rs952570937 611 dbSNP
rs1028162467 612 dbSNP
rs568686222 618 dbSNP
rs975282586 623 dbSNP
rs756133274 624 dbSNP
rs1467621950 628 dbSNP
rs1193788200 633 dbSNP
rs965199004 638 dbSNP
rs1254493112 640 dbSNP
rs1439948460 642 dbSNP
rs1019475256 646 dbSNP
rs1008964901 650 dbSNP
rs1239560523 651 dbSNP
rs1192046207 654 dbSNP
rs1373382498 655 dbSNP
rs2913922 657 dbSNP
rs1467627770 658 dbSNP
rs1031637299 659 dbSNP
rs1162659444 662 dbSNP
rs770789416 663 dbSNP
rs1000407666 667 dbSNP
rs532235231 668 dbSNP
rs767740984 674 dbSNP
rs1211529162 681 dbSNP
rs987515059 682 dbSNP
rs1392972284 684 dbSNP
rs948919452 686 dbSNP
rs895969452 688 dbSNP
rs1057304100 699 dbSNP
rs1295166250 711 dbSNP
rs1220900765 712 dbSNP
rs1259948944 729 dbSNP
rs1239426498 730 dbSNP
rs1377932905 731 dbSNP
rs1311733403 732 dbSNP
rs566420995 732 dbSNP
rs1204143300 738 dbSNP
rs796174742 738 dbSNP
rs1430056301 741 dbSNP
rs1185601457 751 dbSNP
rs1253199765 751 dbSNP
rs1417074103 751 dbSNP
rs35639897 751 dbSNP
rs370622610 751 dbSNP
rs386388507 751 dbSNP
rs535279954 751 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_ControlB_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell Control B ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' gaCACACUC-CUUGUUCUCUGUu 5'
            | | ||| ||: :||||||| 
Target 5' caGAGAGAGAGAGAGAGAGACA- 3'
4 - 25
Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084046. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep4 HITS-CLIP data was present in GSM1084067. RNA binding protein: AGO2. Condition:CLIP_emetine_SantaCruzAb HITS-CLIP data was present in GSM1084072. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084074. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_SantaCruzAb HITS-CLIP data was present in GSM1084076. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_SigmaAb HITS-CLIP data was present in GSM1084077. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_SigmaAb HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084082. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_SigmaAb HITS-CLIP data was present in GSM1084083. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset Chi_ControlB_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell Control B
Location of target site ENST00000338257.8 | 3UTR | ACACAGAGAGAGAGAGAGAGAGACA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084046
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep4
Location of target site ENST00000338257.8 | 3UTR | CAGAGAGAGAGAGAGAGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084067
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_SantaCruzAb
Location of target site ENST00000338257.8 | 3UTR | CACAGAGAGAGAGAGAGAGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1084072
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_AbnovaAb
Location of target site ENST00000338257.8 | 3UTR | CACAGAGAGAGAGAGAGAGAGACA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1084073
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_AbnovaAb
Location of target site ENST00000338257.8 | 3UTR | CACAGAGAGAGAGAGAGAGAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084074
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_SantaCruzAb
Location of target site ENST00000338257.8 | 3UTR | CAGAGAGAGAGAGAGAGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1084076
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_SigmaAb
Location of target site ENST00000338257.8 | 3UTR | AGAGAGAGAGAGAGAGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1084077
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_SigmaAb
Location of target site ENST00000338257.8 | 3UTR | CACAGAGAGAGAGAGAGAGAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000338257.8 | 3UTR | CACAGAGAGAGAGAGAGAGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 10 for dataset GSM1084082
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep2_SigmaAb
Location of target site ENST00000338257.8 | 3UTR | CAGAGAGAGAGAGAGAGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 11 for dataset GSM1084083
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_SigmaAb
Location of target site ENST00000338257.8 | 3UTR | CACAGAGAGAGAGAGAGAGAGACAGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
150 hsa-miR-6818-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT112122 TIMM17A translocase of inner mitochondrial membrane 17A 2 6
MIRT262243 BAMBI BMP and activin membrane bound inhibitor 2 2
MIRT446689 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT449923 TPST2 tyrosylprotein sulfotransferase 2 2 2
MIRT464356 USP12P1 ubiquitin specific peptidase 12 pseudogene 1 2 2
MIRT485703 CBX7 chromobox 7 2 2
MIRT497478 XPR1 xenotropic and polytropic retrovirus receptor 1 2 4
MIRT499435 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT514246 S1PR2 sphingosine-1-phosphate receptor 2 2 2
MIRT515032 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT515065 PLA2G2C phospholipase A2 group IIC 2 2
MIRT520235 USP9X ubiquitin specific peptidase 9, X-linked 2 4
MIRT523685 FHL2 four and a half LIM domains 2 2 4
MIRT525524 FSIP2 fibrous sheath interacting protein 2 2 2
MIRT525838 FAR2 fatty acyl-CoA reductase 2 2 2
MIRT528583 PTGER3 prostaglandin E receptor 3 2 2
MIRT530404 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT530703 RNMTL1 mitochondrial rRNA methyltransferase 3 2 2
MIRT535118 PLSCR4 phospholipid scramblase 4 2 2
MIRT539880 IRGQ immunity related GTPase Q 2 2
MIRT540195 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT540938 SLC25A43 solute carrier family 25 member 43 2 2
MIRT541501 TOR1AIP1 torsin 1A interacting protein 1 2 2
MIRT542544 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT542559 ZNF280B zinc finger protein 280B 2 2
MIRT542689 RPS15A ribosomal protein S15a 2 2
MIRT548759 CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 2 2
MIRT549735 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2 2
MIRT553060 ULK1 unc-51 like autophagy activating kinase 1 2 2
MIRT556303 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT560816 DIP2A disco interacting protein 2 homolog A 2 2
MIRT567455 GLTSCR1 BRD4 interacting chromatin remodeling complex associated protein 2 2
MIRT575143 Cd93 CD93 antigen 2 2
MIRT607217 ACSM2A acyl-CoA synthetase medium chain family member 2A 2 4
MIRT607286 CD300E CD300e molecule 2 6
MIRT607302 RREB1 ras responsive element binding protein 1 2 6
MIRT608645 ABCF3 ATP binding cassette subfamily F member 3 2 4
MIRT611095 MYO1F myosin IF 2 4
MIRT611576 CLEC4D C-type lectin domain family 4 member D 2 2
MIRT614271 WSCD2 WSC domain containing 2 2 2
MIRT614855 PLEKHA6 pleckstrin homology domain containing A6 2 2
MIRT617114 KANK2 KN motif and ankyrin repeat domains 2 2 2
MIRT618002 SLC9A3R2 SLC9A3 regulator 2 2 2
MIRT618028 CTU1 cytosolic thiouridylase subunit 1 2 2
MIRT619062 BSND barttin CLCNK type accessory beta subunit 2 4
MIRT619289 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT619356 CFHR5 complement factor H related 5 2 2
MIRT620725 CCL16 C-C motif chemokine ligand 16 2 2
MIRT620913 LRRTM2 leucine rich repeat transmembrane neuronal 2 2 2
MIRT621902 TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 2 2
MIRT622025 STAT5A signal transducer and activator of transcription 5A 2 2
MIRT622556 PTPN3 protein tyrosine phosphatase, non-receptor type 3 2 2
MIRT623137 NCKAP1 NCK associated protein 1 2 2
MIRT623140 NAV2 neuron navigator 2 2 2
MIRT623701 HHAT hedgehog acyltransferase 2 2
MIRT624602 B3GALT5 beta-1,3-galactosyltransferase 5 2 2
MIRT625944 OLIG3 oligodendrocyte transcription factor 3 2 2
MIRT625988 SPATA17 spermatogenesis associated 17 2 2
MIRT628028 LSAMP limbic system-associated membrane protein 2 2
MIRT635521 MC2R melanocortin 2 receptor 2 2
MIRT638916 CALCOCO2 calcium binding and coiled-coil domain 2 2 2
MIRT639796 EPX eosinophil peroxidase 2 2
MIRT640344 C1orf210 chromosome 1 open reading frame 210 2 2
MIRT644806 VLDLR very low density lipoprotein receptor 2 2
MIRT645303 AGTRAP angiotensin II receptor associated protein 2 2
MIRT645629 SYTL4 synaptotagmin like 4 2 2
MIRT645683 TBC1D13 TBC1 domain family member 13 2 2
MIRT646216 DUSP10 dual specificity phosphatase 10 2 2
MIRT648505 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT649748 UTP20 UTP20, small subunit processome component 2 2
MIRT649797 CLEC2D C-type lectin domain family 2 member D 2 2
MIRT650482 UFM1 ubiquitin fold modifier 1 2 2
MIRT653199 SP9 Sp9 transcription factor 2 2
MIRT655741 NR2F2 nuclear receptor subfamily 2 group F member 2 2 2
MIRT659978 C2CD2L C2CD2 like 2 2
MIRT660350 BAG4 BCL2 associated athanogene 4 2 2
MIRT662185 MEI1 meiotic double-stranded break formation protein 1 2 2
MIRT663290 TECPR2 tectonin beta-propeller repeat containing 2 2 2
MIRT666817 PRCP prolylcarboxypeptidase 2 2
MIRT671665 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT671838 PDE3A phosphodiesterase 3A 2 2
MIRT672193 F2 coagulation factor II, thrombin 2 2
MIRT673870 KLF2 Kruppel like factor 2 2 2
MIRT683563 CARD8 caspase recruitment domain family member 8 2 2
MIRT684545 ZNF708 zinc finger protein 708 2 2
MIRT685140 TACR3 tachykinin receptor 3 2 2
MIRT685413 ACAD8 acyl-CoA dehydrogenase family member 8 2 2
MIRT686039 SLC5A5 solute carrier family 5 member 5 2 2
MIRT686126 B4GALT7 beta-1,4-galactosyltransferase 7 2 2
MIRT687473 NHLRC2 NHL repeat containing 2 2 2
MIRT687946 HHIP hedgehog interacting protein 2 2
MIRT688171 FRRS1 ferric chelate reductase 1 2 2
MIRT688295 FAM208A family with sequence similarity 208 member A 2 2
MIRT689044 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT689194 ZNF574 zinc finger protein 574 2 2
MIRT691253 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT695358 PHAX phosphorylated adaptor for RNA export 2 2
MIRT696674 APOC3 apolipoprotein C3 2 2
MIRT697358 ZNF394 zinc finger protein 394 2 2
MIRT697604 XIAP X-linked inhibitor of apoptosis 2 2
MIRT697726 USP6NL USP6 N-terminal like 2 2
MIRT697776 UBXN7 UBX domain protein 7 2 2
MIRT698478 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT698984 SPAG9 sperm associated antigen 9 2 2
MIRT699851 SAR1B secretion associated Ras related GTPase 1B 2 2
MIRT700172 RIMKLB ribosomal modification protein rimK like family member B 2 2
MIRT704339 DCAF16 DDB1 and CUL4 associated factor 16 2 2
MIRT704589 CLN8 CLN8, transmembrane ER and ERGIC protein 2 2
MIRT705836 AHCY adenosylhomocysteinase 2 2
MIRT707085 TIMM50 translocase of inner mitochondrial membrane 50 2 2
MIRT707132 TRA2B transformer 2 beta homolog 2 2
MIRT707145 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT707234 H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase 2 2
MIRT707347 XPNPEP3 X-prolyl aminopeptidase 3 2 2
MIRT707445 PPFIBP1 PPFIA binding protein 1 2 2
MIRT707494 AXL AXL receptor tyrosine kinase 2 2
MIRT707638 CRIPT CXXC repeat containing interactor of PDZ3 domain 2 2
MIRT707690 FAM118A family with sequence similarity 118 member A 2 2
MIRT707706 CDC6 cell division cycle 6 2 2
MIRT707817 TMEM170A transmembrane protein 170A 2 2
MIRT707957 PDK3 pyruvate dehydrogenase kinase 3 2 2
MIRT707996 NUDT4 nudix hydrolase 4 2 2
MIRT708026 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT708058 LIX1L limb and CNS expressed 1 like 2 2
MIRT708089 KIAA1671 KIAA1671 2 2
MIRT708125 GK5 glycerol kinase 5 (putative) 2 2
MIRT708194 ANP32E acidic nuclear phosphoprotein 32 family member E 2 2
MIRT708201 AHSA2 activator of HSP90 ATPase homolog 2 2 2
MIRT710503 BSDC1 BSD domain containing 1 2 2
MIRT711308 IFNGR2 interferon gamma receptor 2 2 2
MIRT711740 DTX1 deltex E3 ubiquitin ligase 1 2 2
MIRT713202 SOCS6 suppressor of cytokine signaling 6 2 2
MIRT714380 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT715210 NPVF neuropeptide VF precursor 2 2
MIRT715559 EPHB4 EPH receptor B4 2 2
MIRT715835 SZT2 SZT2, KICSTOR complex subunit 2 2
MIRT716680 HLA-B major histocompatibility complex, class I, B 2 2
MIRT717660 THBS2 thrombospondin 2 2 2
MIRT718132 PALM paralemmin 2 2
MIRT718322 METTL7A methyltransferase like 7A 2 2
MIRT720693 RNF217 ring finger protein 217 2 2
MIRT720727 ELOVL7 ELOVL fatty acid elongase 7 2 2
MIRT721376 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT721983 FAM214B family with sequence similarity 214 member B 2 2
MIRT722163 MRPS15 mitochondrial ribosomal protein S15 2 2
MIRT722881 MOB3A MOB kinase activator 3A 2 2
MIRT723218 FMNL3 formin like 3 2 2
MIRT723788 MUC17 mucin 17, cell surface associated 2 2
MIRT724093 TMEM199 transmembrane protein 199 2 2
MIRT725265 OSTM1 osteopetrosis associated transmembrane protein 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6818-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-6818-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-6818-3p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)

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