pre-miRNA Information | |
---|---|
pre-miRNA | hsa-mir-2355 |
Genomic Coordinates | chr2: 207109987 - 207110073 |
Description | Homo sapiens miR-2355 stem-loop |
Comment | None |
RNA Secondary Structure | ![]() |
Associated Diseases | ![]() |
Mature miRNA Information | ||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mature miRNA | hsa-miR-2355-5p | |||||||||||||||||||||||||||
Sequence | 11| AUCCCCAGAUACAAUGGACAA |31 | |||||||||||||||||||||||||||
Evidence | Experimental | |||||||||||||||||||||||||||
Experiments | SOLiD | |||||||||||||||||||||||||||
Editing Events in miRNAs |
|
|||||||||||||||||||||||||||
SNPs in miRNA |
|
|||||||||||||||||||||||||||
Putative Targets |
miRNA Expression profile | |
---|---|
miRNAs in Extracellular Vesicles |
|
Circulating MicroRNA Expression Profiling |
Gene Information | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene Symbol | HSPA4 | ||||||||||||||||||||
Synonyms | APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY | ||||||||||||||||||||
Description | heat shock protein family A (Hsp70) member 4 | ||||||||||||||||||||
Transcript | NM_002154 | ||||||||||||||||||||
Expression | |||||||||||||||||||||
Putative miRNA Targets on HSPA4 | |||||||||||||||||||||
3'UTR of HSPA4 (miRNA target sites are highlighted) |
>HSPA4|NM_002154|3'UTR 1 TTCCAACACTTGTTTCTATTAAAACAGACTATTATAAAGCTTTAAGTTGTCAACTTTGTTCTAAATATCAACTAGCGCAA 81 GTGAATACTGAAGATTTCTTAGTCAGTTTTTAGGGGATTTTCGGGGAGGGGAAATAGGTAATGTATGGAGCATTTTCACT 161 TCTAAATAGTTAGATACAGAAATTAAGTGCATTGTATCTTTTTCATAATGGTACTATTTAGAAGCCCAGTTAGTCTTACT 241 GAGCTTATGCTTCACTCCTTTATGTTTAACCATGTGTCTACAAGAATAAGTTTGTTTTGGAAAGTTGAGCTATAGCTACA 321 GCTCTAGCTATCCAGCAGACTTTTCATTATGACTTACATGGCAGGAGCTCTAATTATGCTTTAAAAATCTGTTGTGGAGA 401 TTGCTTTAAATGCTCCCTGCCTGGTGTGGGGATGGGGTCCCCCTCTTTGTGAGGGCTGGAGCATGGCACGGCATGGATTA 481 ACACGGCAGAGGAACAAAGGTGTGCTCTGAGCTTCTTCATATTTCACCTTCACCCTCACCTGTGTTCTCTTCCCTCTCTC 561 CCAATAAAAGGGCTCCCATTA Target sites
Provided by authors
Predicted by miRanda
DRVs
SNPs
DRVs & SNPs
|
||||||||||||||||||||
miRNA-target interactions (Predicted by miRanda) |
|
||||||||||||||||||||
DRVs in gene 3'UTRs | |||||||||||||||||||||
SNPs in gene 3'UTRs |
Experimental Support 1 for Functional miRNA-Target Interaction | |||||||
---|---|---|---|---|---|---|---|
miRNA:Target | ---- | ||||||
Validation Method |
|
||||||
Conditions | Hela | ||||||
Location of target site | 3'UTR | ||||||
Tools used in this research | TargetScan , miRTarCLIP , Piranha | ||||||
Original Description (Extracted from the article) |
...
HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control
HITS-CLIP data was present in GSM1048188. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_ptb_knockdown
... - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell. |
||||||
miRNA-target interactions (Provided by authors) |
|
||||||
Article |
- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al. - Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
|
Experimental Support 2 for Functional miRNA-Target Interaction | |
---|---|
miRNA:Target | ---- |
Validation Method |
|
Conditions | HEK293S |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
HITS-CLIP data was present in GSM1084040. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep1
HITS-CLIP data was present in GSM1084042. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep2
HITS-CLIP data was present in GSM1084043. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep2
HITS-CLIP data was present in GSM1084044. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep3
HITS-CLIP data was present in GSM1084045. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep3
HITS-CLIP data was present in GSM1084046. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep4
HITS-CLIP data was present in GSM1084047. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep4
HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb
HITS-CLIP data was present in GSM1084068. RNA binding protein: AGO2. Condition:CLIP_noemetine_SigmaAb
HITS-CLIP data was present in GSM1084069. RNA binding protein: AGO2. Condition:CLIP_emetine_SigmaAb
HITS-CLIP data was present in GSM1084072. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_AbnovaAb
HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb
HITS-CLIP data was present in GSM1084076. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_SigmaAb
HITS-CLIP data was present in GSM1084077. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_SigmaAb
HITS-CLIP data was present in GSM1084078. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_AbnovaAb
HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb
HITS-CLIP data was present in GSM1084081. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SantaCruzAb
HITS-CLIP data was present in GSM1084082. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_SigmaAb
HITS-CLIP data was present in GSM1084083. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SigmaAb
... - Karginov FV; Hannon GJ, 2013, Genes & development. |
Article |
- Karginov FV; Hannon GJ - Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
|
Experimental Support 3 for Functional miRNA-Target Interaction | |
---|---|
miRNA:Target | ---- |
Validation Method |
|
Conditions | Cardiac Tissues |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
HITS-CLIP data was present in GSM2202479. RNA binding protein: AGO2. Condition:S4_LV_29yo_Male_AGO2_bound_RNA
... - Spengler RM; Zhang X; Cheng C; McLendon JM; et al., 2016, Nucleic acids research. |
Article |
Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP.
- Spengler RM; Zhang X; Cheng C; McLendon JM; et al.- Nucleic acids research, 2016
MicroRNAs (miRs) have emerged as key biological effectors in human health and disease. These small noncoding RNAs are incorporated into Argonaute (Ago) proteins, where they direct post-transcriptional gene silencing via base-pairing with target transcripts. Although miRs have become intriguing biological entities and attractive therapeutic targets, the translational impacts of miR research remain limited by a paucity of empirical miR targeting data, particularly in human primary tissues. Here, to improve our understanding of the diverse roles miRs play in cardiovascular function and disease, we applied high-throughput methods to globally profile miR:target interactions in human heart tissues. We deciphered Ago2:RNA interactions using crosslinking immunoprecipitation coupled with high-throughput sequencing (HITS-CLIP) to generate the first transcriptome-wide map of miR targeting events in human myocardium, detecting 4000 cardiac Ago2 binding sites across >2200 target transcripts. Our initial exploration of this interactome revealed an abundance of miR target sites in gene coding regions, including several sites pointing to new miR-29 functions in regulating cardiomyocyte calcium, growth and metabolism. Also, we uncovered several clinically-relevant interactions involving common genetic variants that alter miR targeting events in cardiomyopathy-associated genes. Overall, these data provide a critical resource for bolstering translational miR research in heart, and likely beyond.
LinkOut: [PMID: 27418678]
|
CLIP-seq Support 1 for dataset GSM1048187 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | Hela / Hela_AGO2_CLIP_control |
Location of target site | ENST00000304858.2 | 3UTR | GUGUGUGUGUGUGUGUGUGUGGGG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23313552 / GSE42701 |
CLIP-seq Viewer | Link |
CLIP-seq Support 2 for dataset GSM1048188 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | Hela / Hela_AGO2_CLIP_ptb_knockdown |
Location of target site | ENST00000304858.2 | 3UTR | UUUGGUGUGUGUGUGUGUGUGUGUGGGG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23313552 / GSE42701 |
CLIP-seq Viewer | Link |
CLIP-seq Support 3 for dataset GSM1084040 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_noarsenite_rep1 |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 4 for dataset GSM1084042 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_noarsenite_rep2 |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 5 for dataset GSM1084043 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_arsenite_rep2 |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 6 for dataset GSM1084044 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_noarsenite_rep3 |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGUGGGG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 7 for dataset GSM1084045 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_arsenite_rep3 |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 8 for dataset GSM1084046 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_noarsenite_rep4 |
Location of target site | ENST00000304858.2 | 3UTR | UUUUUUGGUGUGUGUGUGUGUGUGUGUGGGGAAGGGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 9 for dataset GSM1084047 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_arsenite_rep4 |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGUG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 10 for dataset GSM1084065 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_emetine_AbnovaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 11 for dataset GSM1084068 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_noemetine_SigmaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGUG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 12 for dataset GSM1084069 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_emetine_SigmaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGUG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 13 for dataset GSM1084072 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_nohippuristanol_rep1_AbnovaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 14 for dataset GSM1084073 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_hippuristanol_rep1_AbnovaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 15 for dataset GSM1084076 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_nohippuristanol_rep1_SigmaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 16 for dataset GSM1084077 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_hippuristanol_rep1_SigmaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 17 for dataset GSM1084078 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_nohippuristanol_rep2_AbnovaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 18 for dataset GSM1084079 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_hippuristanol_rep2_AbnovaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 19 for dataset GSM1084081 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_hippuristanol_rep2_SantaCruzAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 20 for dataset GSM1084082 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_nohippuristanol_rep2_SigmaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
CLIP-seq Support 21 for dataset GSM1084083 | |
---|---|
Method / RBP | HITS-CLIP / AGO2 |
Cell line / Condition | HEK293S / CLIP_hippuristanol_rep2_SigmaAb |
Location of target site | ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23824327 / GSE44404 |
CLIP-seq Viewer | Link |
MiRNA-Target Expression Profile | |||||||
---|---|---|---|---|---|---|---|
|
MiRNA-Target Expression Profile (TCGA) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
164 hsa-miR-2355-5p Target Genes:
Functional analysis:
ID![]() |
Target | Description | Validation methods |
![]() |
![]() |
|||||||
Strong evidence | Less strong evidence | |||||||||||
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |
|||||
MIRT190653 | PABPN1 | poly(A) binding protein nuclear 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT286477 | TAOK1 | TAO kinase 1 | ![]() |
![]() |
2 | 4 | ||||||
MIRT318993 | GIGYF1 | GRB10 interacting GYF protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT345622 | DCAF7 | DDB1 and CUL4 associated factor 7 | ![]() |
![]() |
2 | 4 | ||||||
MIRT442513 | SYT7 | synaptotagmin 7 | ![]() |
![]() |
2 | 4 | ||||||
MIRT444247 | CTNND1 | catenin delta 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT444780 | ECE1 | endothelin converting enzyme 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT456525 | TMEM63A | transmembrane protein 63A | ![]() |
![]() |
2 | 2 | ||||||
MIRT468960 | RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT469834 | R3HDM4 | R3H domain containing 4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT470027 | PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT471167 | PHB2 | prohibitin 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT475819 | HDGF | heparin binding growth factor | ![]() |
![]() |
2 | 4 | ||||||
MIRT479389 | CDKN1B | cyclin dependent kinase inhibitor 1B | ![]() |
![]() |
2 | 6 | ||||||
MIRT481747 | APH1A | aph-1 homolog A, gamma-secretase subunit | ![]() |
![]() |
2 | 2 | ||||||
MIRT485220 | PRICKLE1 | prickle planar cell polarity protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT487259 | CCNF | cyclin F | ![]() |
![]() |
2 | 2 | ||||||
MIRT489971 | MCC | mutated in colorectal cancers | ![]() |
![]() |
2 | 4 | ||||||
MIRT491399 | C1D | C1D nuclear receptor corepressor | ![]() |
![]() |
2 | 2 | ||||||
MIRT494959 | CCDC144A | coiled-coil domain containing 144A | ![]() |
![]() |
2 | 4 | ||||||
MIRT494979 | PPP5D1 | PPP5 tetratricopeptide repeat domain containing 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT495225 | CHST14 | carbohydrate sulfotransferase 14 | ![]() |
![]() |
2 | 2 | ||||||
MIRT496550 | TBX15 | T-box 15 | ![]() |
![]() |
2 | 2 | ||||||
MIRT501612 | PISD | phosphatidylserine decarboxylase | ![]() |
![]() |
2 | 2 | ||||||
MIRT509393 | TRIM24 | tripartite motif containing 24 | ![]() |
![]() |
2 | 2 | ||||||
MIRT519616 | ZNF788 | zinc finger family member 788 | ![]() |
![]() |
2 | 4 | ||||||
MIRT519738 | ZNF394 | zinc finger protein 394 | ![]() |
![]() |
2 | 4 | ||||||
MIRT521230 | SAR1A | secretion associated Ras related GTPase 1A | ![]() |
![]() |
2 | 4 | ||||||
MIRT521801 | POM121C | POM121 transmembrane nucleoporin C | ![]() |
![]() |
2 | 2 | ||||||
MIRT526233 | C2orf15 | chromosome 2 open reading frame 15 | ![]() |
![]() |
2 | 2 | ||||||
MIRT526932 | CMSS1 | cms1 ribosomal small subunit homolog (yeast) | ![]() |
![]() |
2 | 2 | ||||||
MIRT529189 | ACBD7 | acyl-CoA binding domain containing 7 | ![]() |
![]() |
2 | 2 | ||||||
MIRT529329 | ZNF649 | zinc finger protein 649 | ![]() |
![]() |
2 | 2 | ||||||
MIRT529698 | MRPL30 | mitochondrial ribosomal protein L30 | ![]() |
![]() |
2 | 2 | ||||||
MIRT529921 | TOP1MT | DNA topoisomerase I mitochondrial | ![]() |
![]() |
2 | 2 | ||||||
MIRT530032 | SMC1A | structural maintenance of chromosomes 1A | ![]() |
![]() |
2 | 2 | ||||||
MIRT530898 | C9orf3 | chromosome 9 open reading frame 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT531621 | TM4SF5 | transmembrane 4 L six family member 5 | ![]() |
![]() |
2 | 4 | ||||||
MIRT533132 | XIAP | X-linked inhibitor of apoptosis | ![]() |
![]() |
2 | 2 | ||||||
MIRT533210 | WAPAL | WAPL cohesin release factor | ![]() |
![]() |
2 | 2 | ||||||
MIRT534058 | ST6GALNAC3 | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT535487 | PARVB | parvin beta | ![]() |
![]() |
2 | 2 | ||||||
MIRT536749 | HOXD9 | homeobox D9 | ![]() |
![]() |
2 | 2 | ||||||
MIRT551456 | CARKD | NAD(P)HX dehydratase | ![]() |
![]() |
2 | 2 | ||||||
MIRT551858 | ASB6 | ankyrin repeat and SOCS box containing 6 | ![]() |
![]() |
2 | 2 | ||||||
MIRT552095 | FAM8A1 | family with sequence similarity 8 member A1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT552332 | ZNF704 | zinc finger protein 704 | ![]() |
![]() |
2 | 2 | ||||||
MIRT552549 | ZFP36L2 | ZFP36 ring finger protein like 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT561505 | SRSF2 | serine and arginine rich splicing factor 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT562702 | ZNF415 | zinc finger protein 415 | ![]() |
![]() |
2 | 2 | ||||||
MIRT563052 | ZNF138 | zinc finger protein 138 | ![]() |
![]() |
2 | 2 | ||||||
MIRT564592 | ZNF791 | zinc finger protein 791 | ![]() |
![]() |
2 | 2 | ||||||
MIRT566422 | PIGA | phosphatidylinositol glycan anchor biosynthesis class A | ![]() |
![]() |
2 | 2 | ||||||
MIRT570176 | RCBTB1 | RCC1 and BTB domain containing protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT570866 | ZNF525 | zinc finger protein 525 | ![]() |
![]() |
2 | 2 | ||||||
MIRT570875 | ZFP1 | ZFP1 zinc finger protein | ![]() |
![]() |
2 | 2 | ||||||
MIRT571517 | ZNF625 | zinc finger protein 625 | ![]() |
![]() |
2 | 2 | ||||||
MIRT572551 | DKK3 | dickkopf WNT signaling pathway inhibitor 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT610894 | HINFP | histone H4 transcription factor | ![]() |
![]() |
2 | 2 | ||||||
MIRT611037 | PTGES | prostaglandin E synthase | ![]() |
![]() |
2 | 2 | ||||||
MIRT611479 | HSPA4 | heat shock protein family A (Hsp70) member 4 | ![]() |
![]() |
2 | 4 | ||||||
MIRT612419 | SP1 | Sp1 transcription factor | ![]() |
![]() |
2 | 2 | ||||||
MIRT614478 | FRMPD3 | FERM and PDZ domain containing 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT616318 | CACNA1A | calcium voltage-gated channel subunit alpha1 A | ![]() |
![]() |
2 | 2 | ||||||
MIRT616929 | ZNF638 | zinc finger protein 638 | ![]() |
![]() |
2 | 2 | ||||||
MIRT618131 | GABARAPL3 | GABA type A receptor associated protein like 3 pseudogene | ![]() |
![]() |
2 | 2 | ||||||
MIRT618452 | ZFP30 | ZFP30 zinc finger protein | ![]() |
![]() |
2 | 4 | ||||||
MIRT620671 | BBS5 | Bardet-Biedl syndrome 5 | ![]() |
![]() |
2 | 2 | ||||||
MIRT620713 | ASB16 | ankyrin repeat and SOCS box containing 16 | ![]() |
![]() |
2 | 2 | ||||||
MIRT621126 | EMC7 | ER membrane protein complex subunit 7 | ![]() |
![]() |
2 | 4 | ||||||
MIRT621443 | TOMM22 | translocase of outer mitochondrial membrane 22 | ![]() |
![]() |
2 | 2 | ||||||
MIRT623491 | KCTD11 | potassium channel tetramerization domain containing 11 | ![]() |
![]() |
2 | 2 | ||||||
MIRT623783 | GOSR1 | golgi SNAP receptor complex member 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT623918 | FNBP1L | formin binding protein 1 like | ![]() |
![]() |
2 | 2 | ||||||
MIRT625723 | CXorf38 | chromosome X open reading frame 38 | ![]() |
![]() |
2 | 2 | ||||||
MIRT625778 | GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT626940 | TTR | transthyretin | ![]() |
![]() |
2 | 2 | ||||||
MIRT627357 | TSC22D2 | TSC22 domain family member 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT632078 | ALDH1A2 | aldehyde dehydrogenase 1 family member A2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT633361 | FAM71F2 | family with sequence similarity 71 member F2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT639793 | MVK | mevalonate kinase | ![]() |
![]() |
2 | 2 | ||||||
MIRT643761 | NAGK | N-acetylglucosamine kinase | ![]() |
![]() |
2 | 2 | ||||||
MIRT644358 | NDUFAF6 | NADH:ubiquinone oxidoreductase complex assembly factor 6 | ![]() |
![]() |
2 | 2 | ||||||
MIRT645558 | ZMYM1 | zinc finger MYM-type containing 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT646588 | ANKRD36 | ankyrin repeat domain 36 | ![]() |
![]() |
2 | 2 | ||||||
MIRT646631 | SLC25A46 | solute carrier family 25 member 46 | ![]() |
![]() |
2 | 2 | ||||||
MIRT648066 | HSPA6 | heat shock protein family A (Hsp70) member 6 | ![]() |
![]() |
2 | 2 | ||||||
MIRT648142 | SUCLG2 | succinate-CoA ligase GDP-forming beta subunit | ![]() |
![]() |
2 | 2 | ||||||
MIRT648416 | MYOZ3 | myozenin 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT649218 | AMMECR1L | AMMECR1 like | ![]() |
![]() |
2 | 2 | ||||||
MIRT649772 | MRPS27 | mitochondrial ribosomal protein S27 | ![]() |
![]() |
2 | 4 | ||||||
MIRT650510 | UFM1 | ubiquitin fold modifier 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT651007 | ZNF740 | zinc finger protein 740 | ![]() |
![]() |
2 | 2 | ||||||
MIRT651524 | WNT2B | Wnt family member 2B | ![]() |
![]() |
2 | 2 | ||||||
MIRT652014 | TTYH3 | tweety family member 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT652513 | TMEM109 | transmembrane protein 109 | ![]() |
![]() |
2 | 2 | ||||||
MIRT652686 | THUMPD3 | THUMP domain containing 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT652772 | TENM3 | teneurin transmembrane protein 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT653160 | SPRY4 | sprouty RTK signaling antagonist 4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT653765 | SIX5 | SIX homeobox 5 | ![]() |
![]() |
2 | 2 | ||||||
MIRT653792 | SIRPA | signal regulatory protein alpha | ![]() |
![]() |
2 | 2 | ||||||
MIRT655649 | OAZ2 | ornithine decarboxylase antizyme 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT656263 | MEX3A | mex-3 RNA binding family member A | ![]() |
![]() |
2 | 2 | ||||||
MIRT657044 | KCNH6 | potassium voltage-gated channel subfamily H member 6 | ![]() |
![]() |
2 | 2 | ||||||
MIRT657375 | HMGA1 | high mobility group AT-hook 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT657532 | GTDC1 | glycosyltransferase like domain containing 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT657542 | GSTO2 | glutathione S-transferase omega 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT657828 | GJD3 | gap junction protein delta 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT658946 | DOK6 | docking protein 6 | ![]() |
![]() |
2 | 2 | ||||||
MIRT660363 | BACH2 | BTB domain and CNC homolog 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT660406 | ATXN7L3 | ataxin 7 like 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT660948 | ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | ![]() |
![]() |
2 | 2 | ||||||
MIRT661031 | AAK1 | AP2 associated kinase 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT662435 | RALGAPA1 | Ral GTPase activating protein catalytic alpha subunit 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT668419 | FAM217B | family with sequence similarity 217 member B | ![]() |
![]() |
2 | 2 | ||||||
MIRT669332 | BSND | barttin CLCNK type accessory beta subunit | ![]() |
![]() |
2 | 2 | ||||||
MIRT676105 | CLUAP1 | clusterin associated protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT677084 | SMIM15 | small integral membrane protein 15 | ![]() |
![]() |
2 | 2 | ||||||
MIRT677127 | OGFOD3 | 2-oxoglutarate and iron dependent oxygenase domain containing 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT678001 | CPM | carboxypeptidase M | ![]() |
![]() |
2 | 2 | ||||||
MIRT678531 | TMEM78 | transmembrane protein 78 | ![]() |
![]() |
2 | 2 | ||||||
MIRT680000 | ZNF860 | zinc finger protein 860 | ![]() |
![]() |
2 | 2 | ||||||
MIRT680098 | PXMP4 | peroxisomal membrane protein 4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT686795 | SOX12 | SRY-box 12 | ![]() |
![]() |
2 | 2 | ||||||
MIRT698887 | SPTBN2 | spectrin beta, non-erythrocytic 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT699371 | SLC30A6 | solute carrier family 30 member 6 | ![]() |
![]() |
2 | 2 | ||||||
MIRT702005 | MIDN | midnolin | ![]() |
![]() |
2 | 2 | ||||||
MIRT708101 | IGF2BP1 | insulin like growth factor 2 mRNA binding protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT709563 | GYG2 | glycogenin 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT710559 | PPP2R5E | protein phosphatase 2 regulatory subunit B'epsilon | ![]() |
![]() |
2 | 2 | ||||||
MIRT710585 | CDCA4 | cell division cycle associated 4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT710873 | NT5DC1 | 5'-nucleotidase domain containing 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT711876 | VASP | vasodilator stimulated phosphoprotein | ![]() |
![]() |
2 | 2 | ||||||
MIRT712226 | RIMS3 | regulating synaptic membrane exocytosis 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT713211 | FAM13A | family with sequence similarity 13 member A | ![]() |
![]() |
2 | 2 | ||||||
MIRT713261 | GPR55 | G protein-coupled receptor 55 | ![]() |
![]() |
2 | 2 | ||||||
MIRT713327 | DNAJC28 | DnaJ heat shock protein family (Hsp40) member C28 | ![]() |
![]() |
2 | 2 | ||||||
MIRT713889 | RNF19B | ring finger protein 19B | ![]() |
![]() |
2 | 2 | ||||||
MIRT714015 | UBAP2L | ubiquitin associated protein 2 like | ![]() |
![]() |
2 | 2 | ||||||
MIRT714202 | NLRP12 | NLR family pyrin domain containing 12 | ![]() |
![]() |
2 | 2 | ||||||
MIRT714717 | VPS8 | VPS8, CORVET complex subunit | ![]() |
![]() |
2 | 2 | ||||||
MIRT714748 | ZNF385D | zinc finger protein 385D | ![]() |
![]() |
2 | 2 | ||||||
MIRT714806 | ARHGEF19 | Rho guanine nucleotide exchange factor 19 | ![]() |
![]() |
2 | 2 | ||||||
MIRT714852 | ADAMTS17 | ADAM metallopeptidase with thrombospondin type 1 motif 17 | ![]() |
![]() |
2 | 2 | ||||||
MIRT715717 | MRPL4 | mitochondrial ribosomal protein L4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT715852 | GRIN2A | glutamate ionotropic receptor NMDA type subunit 2A | ![]() |
![]() |
2 | 2 | ||||||
MIRT716853 | MFSD12 | major facilitator superfamily domain containing 12 | ![]() |
![]() |
2 | 2 | ||||||
MIRT717134 | EBPL | emopamil binding protein like | ![]() |
![]() |
2 | 2 | ||||||
MIRT717248 | TMEM246 | transmembrane protein 246 | ![]() |
![]() |
2 | 2 | ||||||
MIRT717997 | ZNF79 | zinc finger protein 79 | ![]() |
![]() |
2 | 2 | ||||||
MIRT718341 | PURA | purine rich element binding protein A | ![]() |
![]() |
2 | 2 | ||||||
MIRT719587 | TFCP2L1 | transcription factor CP2 like 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT720520 | PTGR2 | prostaglandin reductase 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT720671 | SLC39A13 | solute carrier family 39 member 13 | ![]() |
![]() |
2 | 2 | ||||||
MIRT721213 | DCLK3 | doublecortin like kinase 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT721757 | INF2 | inverted formin, FH2 and WH2 domain containing | ![]() |
![]() |
2 | 2 | ||||||
MIRT721826 | POU6F1 | POU class 6 homeobox 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT722091 | SUSD1 | sushi domain containing 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT722275 | LURAP1 | leucine rich adaptor protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT722802 | ARHGAP19 | Rho GTPase activating protein 19 | ![]() |
![]() |
2 | 2 | ||||||
MIRT722866 | FAM212B | family with sequence similarity 212 member B | ![]() |
![]() |
2 | 2 | ||||||
MIRT723113 | ZSCAN16 | zinc finger and SCAN domain containing 16 | ![]() |
![]() |
2 | 2 | ||||||
MIRT724378 | NEK8 | NIMA related kinase 8 | ![]() |
![]() |
2 | 2 | ||||||
MIRT732775 | PYCR1 | pyrroline-5-carboxylate reductase 1 | ![]() |
![]() |
![]() |
3 | 0 |
miRNA-Drug Resistance Associations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|