pre-miRNA Information
pre-miRNA hsa-mir-2355   
Genomic Coordinates chr2: 207109987 - 207110073
Description Homo sapiens miR-2355 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-2355-5p
Sequence 11| AUCCCCAGAUACAAUGGACAA |31
Evidence Experimental
Experiments SOLiD
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 1 2 - 207110063 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1268296297 4 dbSNP
rs1361046879 5 dbSNP
rs1219551997 6 dbSNP
rs1295756820 12 dbSNP
rs1345273529 15 dbSNP
rs977145706 15 dbSNP
rs1209629984 20 dbSNP
rs759940260 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol HSPA4   
Synonyms APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY
Description heat shock protein family A (Hsp70) member 4
Transcript NM_002154   
Expression
Putative miRNA Targets on HSPA4
3'UTR of HSPA4
(miRNA target sites are highlighted)
>HSPA4|NM_002154|3'UTR
   1 TTCCAACACTTGTTTCTATTAAAACAGACTATTATAAAGCTTTAAGTTGTCAACTTTGTTCTAAATATCAACTAGCGCAA
  81 GTGAATACTGAAGATTTCTTAGTCAGTTTTTAGGGGATTTTCGGGGAGGGGAAATAGGTAATGTATGGAGCATTTTCACT
 161 TCTAAATAGTTAGATACAGAAATTAAGTGCATTGTATCTTTTTCATAATGGTACTATTTAGAAGCCCAGTTAGTCTTACT
 241 GAGCTTATGCTTCACTCCTTTATGTTTAACCATGTGTCTACAAGAATAAGTTTGTTTTGGAAAGTTGAGCTATAGCTACA
 321 GCTCTAGCTATCCAGCAGACTTTTCATTATGACTTACATGGCAGGAGCTCTAATTATGCTTTAAAAATCTGTTGTGGAGA
 401 TTGCTTTAAATGCTCCCTGCCTGGTGTGGGGATGGGGTCCCCCTCTTTGTGAGGGCTGGAGCATGGCACGGCATGGATTA
 481 ACACGGCAGAGGAACAAAGGTGTGCTCTGAGCTTCTTCATATTTCACCTTCACCCTCACCTGTGTTCTCTTCCCTCTCTC
 561 CCAATAAAAGGGCTCCCATTA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' aacAGGUA---ACAUAGACCCCUa 5'
             ||| |   || :| |||||| 
Target 5' tgcTCCCTGCCTG-GTGTGGGGAt 3'
411 - 433 121.00 -14.20
2
miRNA  3' aaCAGGUAACAUAGACCCCUa 5'
            ||| :|| | |: ||||| 
Target 5' taGTCAGTT-T-TTAGGGGAt 3'
100 - 118 109.00 -12.10
3
miRNA  3' aacaGGUAACA---UAGACCCCua 5'
              :| ||||   : |||| |  
Target 5' ccccTCTTTGTGAGGGCTGGAGca 3'
440 - 463 97.00 -10.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31503660 22 COSMIC
COSN28854796 33 COSMIC
COSN20075265 101 COSMIC
COSN30528066 114 COSMIC
COSN2070712 130 COSMIC
COSN28886015 140 COSMIC
COSN32062630 236 COSMIC
COSN25602574 284 COSMIC
COSN20493132 574 COSMIC
COSN21135180 693 COSMIC
COSN29284887 1252 COSMIC
COSN7875180 1488 COSMIC
COSN8381327 1577 COSMIC
COSN24913440 1648 COSMIC
COSN21214933 1653 COSMIC
COSN17908070 1667 COSMIC
COSN27344410 1667 COSMIC
COSN28453761 1670 COSMIC
COSN27567670 1727 COSMIC
COSN21545974 1769 COSMIC
COSN2070713 1972 COSMIC
COSN4843551 1977 COSMIC
COSN1307441 1999 COSMIC
rs571173399 1672 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1223131828 2 dbSNP
rs11289 3 dbSNP
rs1269079420 6 dbSNP
rs1479939281 11 dbSNP
rs181140417 17 dbSNP
rs752003122 19 dbSNP
rs1192741747 29 dbSNP
rs776057437 30 dbSNP
rs1157889853 33 dbSNP
rs762421599 36 dbSNP
rs1398967973 39 dbSNP
rs767749584 40 dbSNP
rs750839090 41 dbSNP
rs1366428323 50 dbSNP
rs1192330420 60 dbSNP
rs571731462 66 dbSNP
rs923029249 72 dbSNP
rs1239917238 73 dbSNP
rs999040730 75 dbSNP
rs73272759 77 dbSNP
rs954450469 78 dbSNP
rs1424240477 82 dbSNP
rs1050581799 85 dbSNP
rs1161942362 89 dbSNP
rs1007348502 91 dbSNP
rs185596478 97 dbSNP
rs1367715201 101 dbSNP
rs911434178 102 dbSNP
rs1359930062 108 dbSNP
rs1288405250 116 dbSNP
rs1017672216 123 dbSNP
rs1359697499 124 dbSNP
rs1432637554 138 dbSNP
rs560851068 139 dbSNP
rs117408810 141 dbSNP
rs1038633904 145 dbSNP
rs552785949 146 dbSNP
rs1416728805 150 dbSNP
rs14355 158 dbSNP
rs1296722572 165 dbSNP
rs747489619 172 dbSNP
rs140572827 178 dbSNP
rs1275862277 184 dbSNP
rs981919189 192 dbSNP
rs771481772 195 dbSNP
rs938766677 197 dbSNP
rs1293435271 201 dbSNP
rs1359729108 206 dbSNP
rs1228980471 213 dbSNP
rs551963404 217 dbSNP
rs1314644944 220 dbSNP
rs1412918532 227 dbSNP
rs1374599769 229 dbSNP
rs776973915 233 dbSNP
rs947422347 236 dbSNP
rs1486801705 241 dbSNP
rs1187091090 243 dbSNP
rs548713405 251 dbSNP
rs1255174247 252 dbSNP
rs568433852 259 dbSNP
rs534186527 262 dbSNP
rs1186400287 264 dbSNP
rs1475191010 271 dbSNP
rs1442500641 272 dbSNP
rs1479749442 273 dbSNP
rs1185218233 282 dbSNP
rs998988097 287 dbSNP
rs1051923161 291 dbSNP
rs758128686 295 dbSNP
rs547673460 296 dbSNP
rs1158469111 302 dbSNP
rs570764014 312 dbSNP
rs1455784272 313 dbSNP
rs373318893 317 dbSNP
rs746220783 319 dbSNP
rs1379111611 320 dbSNP
rs1392933115 331 dbSNP
rs1450838457 333 dbSNP
rs1317619799 354 dbSNP
rs1383068277 356 dbSNP
rs1395995168 358 dbSNP
rs890653818 359 dbSNP
rs1007304456 376 dbSNP
rs1017369556 377 dbSNP
rs1011327156 380 dbSNP
rs963353169 381 dbSNP
rs539253680 390 dbSNP
rs1417702967 392 dbSNP
rs1318246015 398 dbSNP
rs1215920102 399 dbSNP
rs190403601 404 dbSNP
rs35329068 415 dbSNP
rs1020178632 416 dbSNP
rs770003052 424 dbSNP
rs967241297 425 dbSNP
rs1255286502 434 dbSNP
rs150455512 437 dbSNP
rs775599447 438 dbSNP
rs1213163551 443 dbSNP
rs1268695879 446 dbSNP
rs1333997078 446 dbSNP
rs1241176739 452 dbSNP
rs1333753662 455 dbSNP
rs950629834 459 dbSNP
rs1386950866 460 dbSNP
rs1323243767 470 dbSNP
rs535150945 470 dbSNP
rs1445451515 471 dbSNP
rs1160788175 474 dbSNP
rs1176889159 478 dbSNP
rs953161260 485 dbSNP
rs1363551169 486 dbSNP
rs183041294 500 dbSNP
rs1177282159 503 dbSNP
rs1455705664 507 dbSNP
rs572573453 512 dbSNP
rs1159943942 513 dbSNP
rs571669253 515 dbSNP
rs540668149 520 dbSNP
rs959226493 522 dbSNP
rs1465397852 527 dbSNP
rs908914371 529 dbSNP
rs372493739 534 dbSNP
rs991504113 535 dbSNP
rs1468765233 538 dbSNP
rs941527122 539 dbSNP
rs1259878686 540 dbSNP
rs1038518348 552 dbSNP
rs918745678 553 dbSNP
rs1300804526 554 dbSNP
rs1339094157 557 dbSNP
rs1407366304 559 dbSNP
rs930232298 561 dbSNP
rs1440990899 562 dbSNP
rs560621313 579 dbSNP
rs1319758809 583 dbSNP
rs1384893713 585 dbSNP
rs1303727790 592 dbSNP
rs577497046 593 dbSNP
rs1277363426 596 dbSNP
rs1375096912 612 dbSNP
rs1046400328 614 dbSNP
rs916015993 617 dbSNP
rs1374826754 618 dbSNP
rs546062182 622 dbSNP
rs1299992995 626 dbSNP
rs907233282 627 dbSNP
rs139230617 629 dbSNP
rs1263502556 641 dbSNP
rs1486523685 647 dbSNP
rs1277987097 648 dbSNP
rs1233065667 662 dbSNP
rs1339692992 667 dbSNP
rs1271376468 674 dbSNP
rs764052508 675 dbSNP
rs1224624433 678 dbSNP
rs1326285399 688 dbSNP
rs1417225316 696 dbSNP
rs978790671 698 dbSNP
rs138343531 706 dbSNP
rs762843022 707 dbSNP
rs1055887232 723 dbSNP
rs1398925142 724 dbSNP
rs1166166096 725 dbSNP
rs924639638 726 dbSNP
rs1481745639 728 dbSNP
rs1369191475 731 dbSNP
rs934895174 733 dbSNP
rs1476171485 740 dbSNP
rs186226562 742 dbSNP
rs1209914277 743 dbSNP
rs1177850764 751 dbSNP
rs548654323 756 dbSNP
rs1011380409 762 dbSNP
rs748266860 773 dbSNP
rs774622577 781 dbSNP
rs1020105053 785 dbSNP
rs1338166855 790 dbSNP
rs1293425098 796 dbSNP
rs943538756 810 dbSNP
rs1293004975 812 dbSNP
rs1179264073 815 dbSNP
rs1327091438 824 dbSNP
rs1337974834 824 dbSNP
rs1409662748 826 dbSNP
rs997483053 836 dbSNP
rs144078357 861 dbSNP
rs146896292 866 dbSNP
rs995030174 870 dbSNP
rs953082893 872 dbSNP
rs986175679 875 dbSNP
rs1025978898 882 dbSNP
rs1234450357 889 dbSNP
rs1442570998 897 dbSNP
rs886131101 897 dbSNP
rs1436903376 912 dbSNP
rs1273216524 914 dbSNP
rs770082540 915 dbSNP
rs547815663 922 dbSNP
rs1273104207 923 dbSNP
rs1333247220 923 dbSNP
rs1034911680 928 dbSNP
rs971785850 928 dbSNP
rs918797969 936 dbSNP
rs761828730 937 dbSNP
rs1441703913 941 dbSNP
rs570634110 946 dbSNP
rs930119419 947 dbSNP
rs959176027 948 dbSNP
rs539684163 951 dbSNP
rs981723714 956 dbSNP
rs1338683430 961 dbSNP
rs990668582 964 dbSNP
rs928842366 965 dbSNP
rs549829719 966 dbSNP
rs1409848759 973 dbSNP
rs1023434933 978 dbSNP
rs1056171558 990 dbSNP
rs1156625051 990 dbSNP
rs548962095 990 dbSNP
rs1195186983 991 dbSNP
rs1309467308 992 dbSNP
rs1251891682 999 dbSNP
rs1217098780 1000 dbSNP
rs1205546701 1001 dbSNP
rs1282529648 1016 dbSNP
rs569786027 1023 dbSNP
rs191832680 1031 dbSNP
rs1348785293 1042 dbSNP
rs1489867503 1053 dbSNP
rs137911219 1060 dbSNP
rs1041783625 1062 dbSNP
rs565487651 1067 dbSNP
rs934662901 1070 dbSNP
rs987700848 1072 dbSNP
rs997725738 1075 dbSNP
rs534299948 1076 dbSNP
rs889001174 1078 dbSNP
rs943484741 1080 dbSNP
rs1162580709 1087 dbSNP
rs1039195057 1091 dbSNP
rs1406183758 1093 dbSNP
rs750178519 1098 dbSNP
rs529516426 1107 dbSNP
rs1487101345 1110 dbSNP
rs1240866311 1122 dbSNP
rs1428616967 1123 dbSNP
rs1271687969 1130 dbSNP
rs971841220 1131 dbSNP
rs1362443434 1134 dbSNP
rs1208959614 1137 dbSNP
rs1347468446 1139 dbSNP
rs1296326151 1142 dbSNP
rs557772176 1143 dbSNP
rs1047963578 1144 dbSNP
rs577578582 1146 dbSNP
rs1399382907 1149 dbSNP
rs1291245014 1154 dbSNP
rs1357576842 1155 dbSNP
rs1375807534 1156 dbSNP
rs1224731707 1174 dbSNP
rs13718 1175 dbSNP
rs1170448929 1188 dbSNP
rs1003180616 1196 dbSNP
rs1429766841 1197 dbSNP
rs1416839457 1199 dbSNP
rs1186420288 1210 dbSNP
rs1034860794 1212 dbSNP
rs1259998499 1218 dbSNP
rs866909497 1223 dbSNP
rs1191730339 1228 dbSNP
rs1244164699 1230 dbSNP
rs951579950 1237 dbSNP
rs1252107014 1240 dbSNP
rs981995479 1246 dbSNP
rs1305817973 1252 dbSNP
rs79554694 1253 dbSNP
rs1272432919 1257 dbSNP
rs1217897865 1258 dbSNP
rs1356041335 1259 dbSNP
rs928917094 1262 dbSNP
rs937619371 1268 dbSNP
rs1475923309 1271 dbSNP
rs991738159 1277 dbSNP
rs1463244185 1288 dbSNP
rs1169377134 1293 dbSNP
rs1352227829 1293 dbSNP
rs895072717 1295 dbSNP
rs1420669107 1307 dbSNP
rs947384096 1308 dbSNP
rs1382934025 1309 dbSNP
rs1423586763 1309 dbSNP
rs1179139256 1314 dbSNP
rs771054708 1321 dbSNP
rs1479800113 1322 dbSNP
rs184070050 1331 dbSNP
rs1214417082 1333 dbSNP
rs754707441 1338 dbSNP
rs903238470 1346 dbSNP
rs542481292 1347 dbSNP
rs1370755916 1348 dbSNP
rs202055921 1348 dbSNP
rs369970490 1353 dbSNP
rs187511171 1354 dbSNP
rs143376396 1360 dbSNP
rs987479749 1366 dbSNP
rs1364701555 1370 dbSNP
rs192747694 1372 dbSNP
rs1161767731 1374 dbSNP
rs1417499599 1375 dbSNP
rs143973960 1376 dbSNP
rs1194570856 1382 dbSNP
rs1469864397 1385 dbSNP
rs1251267956 1387 dbSNP
rs201845125 1394 dbSNP
rs964988021 1394 dbSNP
rs148218880 1401 dbSNP
rs550010978 1403 dbSNP
rs563679407 1416 dbSNP
rs1380854316 1419 dbSNP
rs1047448929 1420 dbSNP
rs760128893 1425 dbSNP
rs898839622 1427 dbSNP
rs569656812 1455 dbSNP
rs1372502659 1462 dbSNP
rs1323348428 1464 dbSNP
rs1350098586 1472 dbSNP
rs1026089324 1474 dbSNP
rs182624158 1476 dbSNP
rs1003282600 1482 dbSNP
rs1174470450 1483 dbSNP
rs1393301715 1484 dbSNP
rs894851987 1484 dbSNP
rs1036292099 1486 dbSNP
rs548796431 1488 dbSNP
rs1241745066 1492 dbSNP
rs1012145169 1495 dbSNP
rs1044050500 1500 dbSNP
rs1183861627 1502 dbSNP
rs903662777 1506 dbSNP
rs11242133 1509 dbSNP
rs565424130 1517 dbSNP
rs1159804538 1522 dbSNP
rs1298351743 1528 dbSNP
rs1326577566 1528 dbSNP
rs1381067328 1529 dbSNP
rs1385502400 1530 dbSNP
rs1360250975 1531 dbSNP
rs747720062 1532 dbSNP
rs1469291522 1535 dbSNP
rs977362451 1538 dbSNP
rs1334436280 1541 dbSNP
rs924619918 1543 dbSNP
rs1031728502 1559 dbSNP
rs757692334 1563 dbSNP
rs1475780232 1572 dbSNP
rs933423026 1574 dbSNP
rs1051851941 1580 dbSNP
rs187283215 1583 dbSNP
rs1236887506 1585 dbSNP
rs775946366 1589 dbSNP
rs1360514816 1600 dbSNP
rs943182945 1611 dbSNP
rs1486412319 1613 dbSNP
rs1276067032 1623 dbSNP
rs1330410405 1624 dbSNP
rs1223491520 1630 dbSNP
rs557586518 1635 dbSNP
rs571718474 1643 dbSNP
rs1340471965 1645 dbSNP
rs1462900959 1645 dbSNP
rs1294227092 1646 dbSNP
rs10479022 1649 dbSNP
rs11242134 1652 dbSNP
rs1333728842 1652 dbSNP
rs1435725985 1653 dbSNP
rs1410782880 1654 dbSNP
rs1422839131 1654 dbSNP
rs1453890304 1654 dbSNP
rs752113680 1654 dbSNP
rs1165655478 1655 dbSNP
rs1183353583 1656 dbSNP
rs1476060065 1664 dbSNP
rs1247884282 1665 dbSNP
rs1412143606 1665 dbSNP
rs1186357788 1666 dbSNP
rs1196221170 1666 dbSNP
rs1235569471 1666 dbSNP
rs1251985694 1666 dbSNP
rs1336522952 1666 dbSNP
rs572973453 1666 dbSNP
rs1162459205 1667 dbSNP
rs1165529450 1667 dbSNP
rs1176467438 1667 dbSNP
rs1216053356 1667 dbSNP
rs1224688420 1667 dbSNP
rs1239753949 1667 dbSNP
rs1289538020 1667 dbSNP
rs1307327843 1667 dbSNP
rs1326856353 1667 dbSNP
rs1337765478 1667 dbSNP
rs1353371929 1667 dbSNP
rs1365189983 1667 dbSNP
rs1395382972 1667 dbSNP
rs1411311283 1667 dbSNP
rs1446120153 1667 dbSNP
rs1450414612 1667 dbSNP
rs1456920668 1667 dbSNP
rs1462989788 1667 dbSNP
rs1470276638 1667 dbSNP
rs199567901 1667 dbSNP
rs70974072 1667 dbSNP
rs755260897 1667 dbSNP
rs908704087 1668 dbSNP
rs1178933466 1669 dbSNP
rs6874036 1670 dbSNP
rs1431396758 1671 dbSNP
rs571173399 1672 dbSNP
rs878856835 1673 dbSNP
rs1396034977 1674 dbSNP
rs536649341 1675 dbSNP
rs1330948894 1676 dbSNP
rs1351225864 1678 dbSNP
rs1404442782 1679 dbSNP
rs1281874502 1680 dbSNP
rs1326292095 1681 dbSNP
rs1234334279 1682 dbSNP
rs1251176512 1683 dbSNP
rs1337030828 1684 dbSNP
rs1197238089 1685 dbSNP
rs1251872190 1686 dbSNP
rs1490032834 1687 dbSNP
rs1212853409 1688 dbSNP
rs1196681529 1689 dbSNP
rs1156436149 1690 dbSNP
rs1184919692 1690 dbSNP
rs1281039975 1690 dbSNP
rs1368486460 1691 dbSNP
rs1395109201 1691 dbSNP
rs1433767478 1692 dbSNP
rs1477286907 1692 dbSNP
rs1262296904 1693 dbSNP
rs1461445767 1693 dbSNP
rs1217199966 1694 dbSNP
rs1449073712 1694 dbSNP
rs1166055048 1695 dbSNP
rs1169470243 1696 dbSNP
rs1284369978 1697 dbSNP
rs1371175476 1701 dbSNP
rs1348901552 1702 dbSNP
rs1398423645 1704 dbSNP
rs55779432 1705 dbSNP
rs1175194344 1706 dbSNP
rs1375680813 1706 dbSNP
rs1412245923 1706 dbSNP
rs1418653211 1706 dbSNP
rs1423912362 1706 dbSNP
rs56373873 1706 dbSNP
rs80083130 1706 dbSNP
rs1187577604 1707 dbSNP
rs1169828959 1708 dbSNP
rs1371424454 1709 dbSNP
rs1193413361 1710 dbSNP
rs1424028393 1711 dbSNP
rs1301373962 1713 dbSNP
rs1282737584 1714 dbSNP
rs1208356472 1716 dbSNP
rs1347938645 1719 dbSNP
rs1311658245 1722 dbSNP
rs1273853772 1723 dbSNP
rs1037623414 1726 dbSNP
rs539526383 1726 dbSNP
rs1133363 1728 dbSNP
rs1355911364 1734 dbSNP
rs531522424 1743 dbSNP
rs1445406793 1744 dbSNP
rs551625746 1746 dbSNP
rs1295280753 1749 dbSNP
rs1325093349 1751 dbSNP
rs1230116082 1752 dbSNP
rs1274855667 1766 dbSNP
rs141272770 1768 dbSNP
rs781671195 1773 dbSNP
rs1422118776 1775 dbSNP
rs899057034 1782 dbSNP
rs1260116026 1784 dbSNP
rs576854498 1784 dbSNP
rs1180304252 1786 dbSNP
rs1018939054 1789 dbSNP
rs1233469983 1790 dbSNP
rs571356042 1795 dbSNP
rs974993413 1796 dbSNP
rs1217984387 1803 dbSNP
rs1335198394 1811 dbSNP
rs906181501 1813 dbSNP
rs1226213981 1822 dbSNP
rs1378012572 1822 dbSNP
rs533946564 1823 dbSNP
rs1003742999 1833 dbSNP
rs920862973 1834 dbSNP
rs1185898366 1836 dbSNP
rs760205578 1842 dbSNP
rs1462466581 1843 dbSNP
rs766340257 1846 dbSNP
rs1423395661 1851 dbSNP
rs952207019 1851 dbSNP
rs983591471 1853 dbSNP
rs1390943203 1854 dbSNP
rs1444306856 1857 dbSNP
rs1161736109 1858 dbSNP
rs1351742337 1867 dbSNP
rs192116762 1870 dbSNP
rs1021851547 1881 dbSNP
rs908082977 1882 dbSNP
rs1380861483 1883 dbSNP
rs1266933203 1890 dbSNP
rs1288761189 1897 dbSNP
rs1320966691 1898 dbSNP
rs968969734 1913 dbSNP
rs939099573 1914 dbSNP
rs556030750 1915 dbSNP
rs1307939299 1921 dbSNP
rs1373973225 1921 dbSNP
rs373586285 1928 dbSNP
rs1384220007 1932 dbSNP
rs1298803232 1933 dbSNP
rs1393522892 1940 dbSNP
rs1292359263 1942 dbSNP
rs1457707533 1944 dbSNP
rs1346207856 1945 dbSNP
rs924643274 1950 dbSNP
rs916234000 1955 dbSNP
rs947731626 1958 dbSNP
rs1194357751 1963 dbSNP
rs1433638798 1964 dbSNP
rs770088476 1965 dbSNP
rs1243378272 1971 dbSNP
rs954722672 1973 dbSNP
rs1043613269 1986 dbSNP
rs910598758 1986 dbSNP
rs1261135863 1991 dbSNP
rs1474823523 1996 dbSNP
rs1321753560 1999 dbSNP
rs903779269 1999 dbSNP
rs1218290505 2004 dbSNP
rs943201723 2010 dbSNP
rs572700286 2012 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control HITS-CLIP data was present in GSM1048188. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_ptb_knockdown ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' aaCAGGUA-ACAUAGACCCCua 5'
            || ::| |||:| |||||  
Target 5' guGUGUGUGUGUGUGUGGGG-- 3'
9 - 28
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084040. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep1 HITS-CLIP data was present in GSM1084042. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep2 HITS-CLIP data was present in GSM1084043. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep2 HITS-CLIP data was present in GSM1084044. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep3 HITS-CLIP data was present in GSM1084045. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep3 HITS-CLIP data was present in GSM1084046. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep4 HITS-CLIP data was present in GSM1084047. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep4 HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084068. RNA binding protein: AGO2. Condition:CLIP_noemetine_SigmaAb HITS-CLIP data was present in GSM1084069. RNA binding protein: AGO2. Condition:CLIP_emetine_SigmaAb HITS-CLIP data was present in GSM1084072. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084076. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_SigmaAb HITS-CLIP data was present in GSM1084077. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_SigmaAb HITS-CLIP data was present in GSM1084078. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084081. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SantaCruzAb HITS-CLIP data was present in GSM1084082. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_SigmaAb HITS-CLIP data was present in GSM1084083. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Cardiac Tissues
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM2202479. RNA binding protein: AGO2. Condition:S4_LV_29yo_Male_AGO2_bound_RNA ...

- Spengler RM; Zhang X; Cheng C; McLendon JM; et al., 2016, Nucleic acids research.

Article - Spengler RM; Zhang X; Cheng C; McLendon JM; et al.
- Nucleic acids research, 2016
MicroRNAs (miRs) have emerged as key biological effectors in human health and disease. These small noncoding RNAs are incorporated into Argonaute (Ago) proteins, where they direct post-transcriptional gene silencing via base-pairing with target transcripts. Although miRs have become intriguing biological entities and attractive therapeutic targets, the translational impacts of miR research remain limited by a paucity of empirical miR targeting data, particularly in human primary tissues. Here, to improve our understanding of the diverse roles miRs play in cardiovascular function and disease, we applied high-throughput methods to globally profile miR:target interactions in human heart tissues. We deciphered Ago2:RNA interactions using crosslinking immunoprecipitation coupled with high-throughput sequencing (HITS-CLIP) to generate the first transcriptome-wide map of miR targeting events in human myocardium, detecting 4000 cardiac Ago2 binding sites across >2200 target transcripts. Our initial exploration of this interactome revealed an abundance of miR target sites in gene coding regions, including several sites pointing to new miR-29 functions in regulating cardiomyocyte calcium, growth and metabolism. Also, we uncovered several clinically-relevant interactions involving common genetic variants that alter miR targeting events in cardiomyopathy-associated genes. Overall, these data provide a critical resource for bolstering translational miR research in heart, and likely beyond.
LinkOut: [PMID: 27418678]
CLIP-seq Support 1 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000304858.2 | 3UTR | GUGUGUGUGUGUGUGUGUGUGGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1048188
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_ptb_knockdown
Location of target site ENST00000304858.2 | 3UTR | UUUGGUGUGUGUGUGUGUGUGUGUGGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084040
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep1
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1084042
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep2
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1084043
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep2
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084044
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep3
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGUGGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1084045
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep3
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1084046
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep4
Location of target site ENST00000304858.2 | 3UTR | UUUUUUGGUGUGUGUGUGUGUGUGUGUGGGGAAGGGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM1084047
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep4
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 10 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 11 for dataset GSM1084068
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SigmaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 12 for dataset GSM1084069
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_SigmaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 13 for dataset GSM1084072
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_AbnovaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 14 for dataset GSM1084073
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_AbnovaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 15 for dataset GSM1084076
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_SigmaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 16 for dataset GSM1084077
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_SigmaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 17 for dataset GSM1084078
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep2_AbnovaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 18 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 19 for dataset GSM1084081
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_SantaCruzAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 20 for dataset GSM1084082
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep2_SigmaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 21 for dataset GSM1084083
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_SigmaAb
Location of target site ENST00000304858.2 | 3UTR | UUUUGGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
UCEC -0.466 0.02 -0.451 0.03 19 Click to see details
LUAD 0.567 0.03 0.503 0.05 12 Click to see details
THCA 0.224 0.04 0.174 0.09 59 Click to see details
STAD 0.266 0.07 0.366 0.02 32 Click to see details
BRCA -0.15 0.09 -0.166 0.07 84 Click to see details
ESCA 0.439 0.09 0.400 0.11 11 Click to see details
CESC 0.952 0.1 1.000 0.5 3 Click to see details
PCPG 0.921 0.13 1.000 0.5 3 Click to see details
PRAD 0.114 0.22 0.076 0.3 50 Click to see details
HNSC -0.105 0.25 -0.094 0.28 42 Click to see details
CHOL -0.157 0.34 -0.283 0.23 9 Click to see details
KIRC -0.044 0.36 -0.043 0.36 68 Click to see details
LUSC 0.056 0.37 0.039 0.41 38 Click to see details
LIHC -0.04 0.39 0.004 0.49 49 Click to see details
BLCA 0.055 0.41 0.100 0.35 18 Click to see details
PAAD -0.144 0.43 -0.200 0.4 4 Click to see details
KICH 0.021 0.46 -0.004 0.49 25 Click to see details
KIRP 0.007 0.48 -0.061 0.37 32 Click to see details
KIRP 0.007 0.48 -0.061 0.37 32 Click to see details
164 hsa-miR-2355-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT190653 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT286477 TAOK1 TAO kinase 1 2 4
MIRT318993 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT345622 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT442513 SYT7 synaptotagmin 7 2 4
MIRT444247 CTNND1 catenin delta 1 2 2
MIRT444780 ECE1 endothelin converting enzyme 1 2 2
MIRT456525 TMEM63A transmembrane protein 63A 2 2
MIRT468960 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT469834 R3HDM4 R3H domain containing 4 2 2
MIRT470027 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT471167 PHB2 prohibitin 2 2 2
MIRT475819 HDGF heparin binding growth factor 2 4
MIRT479389 CDKN1B cyclin dependent kinase inhibitor 1B 2 6
MIRT481747 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT485220 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT487259 CCNF cyclin F 2 2
MIRT489971 MCC mutated in colorectal cancers 2 4
MIRT491399 C1D C1D nuclear receptor corepressor 2 2
MIRT494959 CCDC144A coiled-coil domain containing 144A 2 4
MIRT494979 PPP5D1 PPP5 tetratricopeptide repeat domain containing 1 2 2
MIRT495225 CHST14 carbohydrate sulfotransferase 14 2 2
MIRT496550 TBX15 T-box 15 2 2
MIRT501612 PISD phosphatidylserine decarboxylase 2 2
MIRT509393 TRIM24 tripartite motif containing 24 2 2
MIRT519616 ZNF788 zinc finger family member 788 2 4
MIRT519738 ZNF394 zinc finger protein 394 2 4
MIRT521230 SAR1A secretion associated Ras related GTPase 1A 2 4
MIRT521801 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT526233 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT526932 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT529189 ACBD7 acyl-CoA binding domain containing 7 2 2
MIRT529329 ZNF649 zinc finger protein 649 2 2
MIRT529698 MRPL30 mitochondrial ribosomal protein L30 2 2
MIRT529921 TOP1MT DNA topoisomerase I mitochondrial 2 2
MIRT530032 SMC1A structural maintenance of chromosomes 1A 2 2
MIRT530898 C9orf3 chromosome 9 open reading frame 3 2 2
MIRT531621 TM4SF5 transmembrane 4 L six family member 5 2 4
MIRT533132 XIAP X-linked inhibitor of apoptosis 2 2
MIRT533210 WAPAL WAPL cohesin release factor 2 2
MIRT534058 ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2 2
MIRT535487 PARVB parvin beta 2 2
MIRT536749 HOXD9 homeobox D9 2 2
MIRT551456 CARKD NAD(P)HX dehydratase 2 2
MIRT551858 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT552095 FAM8A1 family with sequence similarity 8 member A1 2 2
MIRT552332 ZNF704 zinc finger protein 704 2 2
MIRT552549 ZFP36L2 ZFP36 ring finger protein like 2 2 2
MIRT561505 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT562702 ZNF415 zinc finger protein 415 2 2
MIRT563052 ZNF138 zinc finger protein 138 2 2
MIRT564592 ZNF791 zinc finger protein 791 2 2
MIRT566422 PIGA phosphatidylinositol glycan anchor biosynthesis class A 2 2
MIRT570176 RCBTB1 RCC1 and BTB domain containing protein 1 2 2
MIRT570866 ZNF525 zinc finger protein 525 2 2
MIRT570875 ZFP1 ZFP1 zinc finger protein 2 2
MIRT571517 ZNF625 zinc finger protein 625 2 2
MIRT572551 DKK3 dickkopf WNT signaling pathway inhibitor 3 2 2
MIRT610894 HINFP histone H4 transcription factor 2 2
MIRT611037 PTGES prostaglandin E synthase 2 2
MIRT611479 HSPA4 heat shock protein family A (Hsp70) member 4 2 4
MIRT612419 SP1 Sp1 transcription factor 2 2
MIRT614478 FRMPD3 FERM and PDZ domain containing 3 2 2
MIRT616318 CACNA1A calcium voltage-gated channel subunit alpha1 A 2 2
MIRT616929 ZNF638 zinc finger protein 638 2 2
MIRT618131 GABARAPL3 GABA type A receptor associated protein like 3 pseudogene 2 2
MIRT618452 ZFP30 ZFP30 zinc finger protein 2 4
MIRT620671 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT620713 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT621126 EMC7 ER membrane protein complex subunit 7 2 4
MIRT621443 TOMM22 translocase of outer mitochondrial membrane 22 2 2
MIRT623491 KCTD11 potassium channel tetramerization domain containing 11 2 2
MIRT623783 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT623918 FNBP1L formin binding protein 1 like 2 2
MIRT625723 CXorf38 chromosome X open reading frame 38 2 2
MIRT625778 GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2 2
MIRT626940 TTR transthyretin 2 2
MIRT627357 TSC22D2 TSC22 domain family member 2 2 2
MIRT632078 ALDH1A2 aldehyde dehydrogenase 1 family member A2 2 2
MIRT633361 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT639793 MVK mevalonate kinase 2 2
MIRT643761 NAGK N-acetylglucosamine kinase 2 2
MIRT644358 NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 2 2
MIRT645558 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT646588 ANKRD36 ankyrin repeat domain 36 2 2
MIRT646631 SLC25A46 solute carrier family 25 member 46 2 2
MIRT648066 HSPA6 heat shock protein family A (Hsp70) member 6 2 2
MIRT648142 SUCLG2 succinate-CoA ligase GDP-forming beta subunit 2 2
MIRT648416 MYOZ3 myozenin 3 2 2
MIRT649218 AMMECR1L AMMECR1 like 2 2
MIRT649772 MRPS27 mitochondrial ribosomal protein S27 2 4
MIRT650510 UFM1 ubiquitin fold modifier 1 2 2
MIRT651007 ZNF740 zinc finger protein 740 2 2
MIRT651524 WNT2B Wnt family member 2B 2 2
MIRT652014 TTYH3 tweety family member 3 2 2
MIRT652513 TMEM109 transmembrane protein 109 2 2
MIRT652686 THUMPD3 THUMP domain containing 3 2 2
MIRT652772 TENM3 teneurin transmembrane protein 3 2 2
MIRT653160 SPRY4 sprouty RTK signaling antagonist 4 2 2
MIRT653765 SIX5 SIX homeobox 5 2 2
MIRT653792 SIRPA signal regulatory protein alpha 2 2
MIRT655649 OAZ2 ornithine decarboxylase antizyme 2 2 2
MIRT656263 MEX3A mex-3 RNA binding family member A 2 2
MIRT657044 KCNH6 potassium voltage-gated channel subfamily H member 6 2 2
MIRT657375 HMGA1 high mobility group AT-hook 1 2 2
MIRT657532 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT657542 GSTO2 glutathione S-transferase omega 2 2 2
MIRT657828 GJD3 gap junction protein delta 3 2 2
MIRT658946 DOK6 docking protein 6 2 2
MIRT660363 BACH2 BTB domain and CNC homolog 2 2 2
MIRT660406 ATXN7L3 ataxin 7 like 3 2 2
MIRT660948 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT661031 AAK1 AP2 associated kinase 1 2 2
MIRT662435 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT668419 FAM217B family with sequence similarity 217 member B 2 2
MIRT669332 BSND barttin CLCNK type accessory beta subunit 2 2
MIRT676105 CLUAP1 clusterin associated protein 1 2 2
MIRT677084 SMIM15 small integral membrane protein 15 2 2
MIRT677127 OGFOD3 2-oxoglutarate and iron dependent oxygenase domain containing 3 2 2
MIRT678001 CPM carboxypeptidase M 2 2
MIRT678531 TMEM78 transmembrane protein 78 2 2
MIRT680000 ZNF860 zinc finger protein 860 2 2
MIRT680098 PXMP4 peroxisomal membrane protein 4 2 2
MIRT686795 SOX12 SRY-box 12 2 2
MIRT698887 SPTBN2 spectrin beta, non-erythrocytic 2 2 2
MIRT699371 SLC30A6 solute carrier family 30 member 6 2 2
MIRT702005 MIDN midnolin 2 2
MIRT708101 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT709563 GYG2 glycogenin 2 2 2
MIRT710559 PPP2R5E protein phosphatase 2 regulatory subunit B'epsilon 2 2
MIRT710585 CDCA4 cell division cycle associated 4 2 2
MIRT710873 NT5DC1 5'-nucleotidase domain containing 1 2 2
MIRT711876 VASP vasodilator stimulated phosphoprotein 2 2
MIRT712226 RIMS3 regulating synaptic membrane exocytosis 3 2 2
MIRT713211 FAM13A family with sequence similarity 13 member A 2 2
MIRT713261 GPR55 G protein-coupled receptor 55 2 2
MIRT713327 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT713889 RNF19B ring finger protein 19B 2 2
MIRT714015 UBAP2L ubiquitin associated protein 2 like 2 2
MIRT714202 NLRP12 NLR family pyrin domain containing 12 2 2
MIRT714717 VPS8 VPS8, CORVET complex subunit 2 2
MIRT714748 ZNF385D zinc finger protein 385D 2 2
MIRT714806 ARHGEF19 Rho guanine nucleotide exchange factor 19 2 2
MIRT714852 ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 2 2
MIRT715717 MRPL4 mitochondrial ribosomal protein L4 2 2
MIRT715852 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT716853 MFSD12 major facilitator superfamily domain containing 12 2 2
MIRT717134 EBPL emopamil binding protein like 2 2
MIRT717248 TMEM246 transmembrane protein 246 2 2
MIRT717997 ZNF79 zinc finger protein 79 2 2
MIRT718341 PURA purine rich element binding protein A 2 2
MIRT719587 TFCP2L1 transcription factor CP2 like 1 2 2
MIRT720520 PTGR2 prostaglandin reductase 2 2 2
MIRT720671 SLC39A13 solute carrier family 39 member 13 2 2
MIRT721213 DCLK3 doublecortin like kinase 3 2 2
MIRT721757 INF2 inverted formin, FH2 and WH2 domain containing 2 2
MIRT721826 POU6F1 POU class 6 homeobox 1 2 2
MIRT722091 SUSD1 sushi domain containing 1 2 2
MIRT722275 LURAP1 leucine rich adaptor protein 1 2 2
MIRT722802 ARHGAP19 Rho GTPase activating protein 19 2 2
MIRT722866 FAM212B family with sequence similarity 212 member B 2 2
MIRT723113 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT724378 NEK8 NIMA related kinase 8 2 2
MIRT732775 PYCR1 pyrroline-5-carboxylate reductase 1 3 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-2355 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-2355-5p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-2355-5p Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-2355-5p Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-2355-5p Gefitinib 123631 NSC715055 approved resistant High Non-Small Cell Lung Cancer cell line (A549, HCC827)
hsa-miR-2355-5p Temozolomide 5394 NSC362856 approved resistant High Glioma tissue
hsa-miR-2355-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-2355-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-2355-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-2355-5p Tamoxifen+Fulvestrant sensitive cell line (LCC9)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-2355-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (TOV-112D)
hsa-miR-2355-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (OVSAHO)

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