miRTarBase - #MIRT612818


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pre-miRNA Information
pre-miRNA hsa-mir-3618   
Genomic Coordinates chr22: 20085746 - 20085833
Description Homo sapiens miR-3618 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3618
Sequence 52| UGUCUACAUUAAUGAAAAGAGC |73
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 11 22 + 20085807 27587585 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30730356 3 COSMIC
COSN30178222 4 COSMIC
COSN26973254 21 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs12159555 4 dbSNP
rs761877586 8 dbSNP
Putative Targets

Gene Information
Gene Symbol KLHL3   
Synonyms PHA2D
Description kelch like family member 3
Transcript NM_017415   
Expression
Putative miRNA Targets on KLHL3
3'UTR of KLHL3
(miRNA target sites are highlighted)		 
>KLHL3|NM_017415|3'UTR
   1 CCCAAACTCCTACTGCCAGGAGGTGGAGGAAGGAGCAGGTGCTGCCTGTGACTCTGAACAGCAGGACCTTGGTGACTGGA
  81 TTCAACTTGCTTGGGAGGGTCTGTGCTGCTGTGAGAACCGCTCTCCTCTGACTTGGCAGACTGGTGTTGTTCATCGCAGT
 161 GTGGACACCATTACCCACCCCCGTTCCCCTGAGGTGCTCTGGCCTATGCCCTGAGCAAGGGGGGTCTTGACATCCCCAGG
 241 CAGCACCTTTGGGCTTTGTTTTGGTGTTTCTACAGGGACAATACAGACCCTGGAGTGTGTGTGTGTGTGTGTGTGTGTGT
 321 AGACCATGGTGTTTCTCTATGTTTCTCTAAGTTGGGGGGTGAGCGTGTGTGACAGTCTACTGGATTTCTTTACTACTGAT
 401 CCTTTCGCTGTGTTAAAAATCAAGTCACAGAGACCTCTCTTCTGGATTTGTCCCATGGGGACCCTGAGACTACTAAAGCT
 481 GCTTTCTTCTGAAGGTCCAGTTGGACAGTCTGGGAATGTCCAGAAATAACCAGTGAGAGGGGCAGTTCTCTGGCCACACC
 561 CACTTATGTACTTTAACTACTGTGACTTTGTCTGCAGAAGAGCTGGAAAATTCTCGAAGCTGCACCGTGTCCTCTGTGTG
 641 CTAGAATAAGGGACAAATGGGTTCCCTGTGCTTCTCAGCTCACTGTTTTTCCTTGAGTTCTCCTACAGGAAGCAGATGAG
 721 AACTGCCCAGTCTTCAGGTTTAGGCCATTGGTCTTTGATGTCATAGATTCCAGGCCTGGGAGGTGTTATGTCTCTTCAGC
 801 TGGGAAAACTAGCTCTTCAGAGAAGCCTCGGGTAACACTGAAAAACAAAACAAAACAAAACAAAAACAGGAAAAAAACAA
 881 AAAACCAAAGTGGTAAGGATTCAGTTCCTGCCTATAATGGTCTCAGAGAGGGTCCTACTTTTAGGTTTTCCCAGGACAGG
 961 ACAGTCCCCATTTATACTTATTATCCCAGTTTAATTATTCACAGCACCCCATTTTACTCAGAAGTGTTCTGGTCTGGAGG
1041 ATAAATAAGAGGTCACCCTCCTCCAGACCCAAAGATAGATTTGTGCCTGTGTTGGATGGGGTCGTGTGTGATTCAGATGG
1121 ACATTGGATGGCTTCAAAGGAATATACCACTAGAGCTGGCCCTTGGCACTTTGTGACAGTGGTCAAGTCTGTCTAATGTC
1201 CTTGTCTTCTTTTTCTTGTGCTTTCCCCCTATTCCAGGGTGTGCACCCTCTCCCCAACCCCCAAGAACCCCACTACTGCT
1281 TTCCCTGTGAGGTAGGAGATATCAGTGGGCCTTGGATTTGAGGCTTCCTAAGATGTGCTTGCATTTTAAAAAGGGAGCTT
1361 GGTGAGAGCTTTGCTAATTCACAGGTAAAAATTATTAACAATAGAACTTCAAGCATCTTGAGGAGCGGGCATTTGAGGGG
1441 GCATGGAGTAATTTGTATTTAAAAAACCTTAAAGTTGTGCTGTTCCTAAACTAGCAAATTGCTCATGCTGAAATTTCTGG
1521 CATAAGCAGGGGAAGTCTTGTGTCTGGAGAATAGTCTCATACCTTGCAGTCTGGGACACCCTCCCTACTTTGAGAATCCA
1601 CCTACAGGAAGCCAAGGAACTTTATAAATCCTGATGTTGGACTTCTGATACGACTGGGCTACTTCCAAGCAGGTGCTGCA
1681 GGAGATTGGCATCCCCCAGCCCCTGCAGTTAGAAACCCCGAAGTCTTCCCAGCCAGTGAGCCACTTTGTGTATTTACTGT
1761 ATATTTATTGTGCCCTAAATGTGCAACTCTCCTAAAGACAAAACTTCTCTTTCTGATGTTAAGCACATGTTACTTCAACA
1841 AGATGCTTGGAGAACAACAAGGTACCCAGAATTTTTAGAAGCCTTCAGAAGAGGCTAAAATATCCAGCTTTGGGGGACCT
1921 GGAAGAAATGTCTCCAAAGGAAGCAAGGCATGTTTTAGTTGAGTGCTCTGGTCTCACTATGAAGTGGGGATGACTGTGGC
2001 TTCATAACTCTACCTGGCTGTGGGTTGGAAGCTGATGGAATGAGAAATGTCCTTTCTCCTTCTCTGAGGAAATTTTGAGA
2081 CTTGTTTCGGTGTGTCTGTGTGATGGGGATGAGGCTGGGGTTGGGATCTGATGTATGCCATTCACAGAAGCTCTCAATTT
2161 CAGATGATAGGTGAATTCCCTGCCCCTCCCCCACCACTGAGAAGCTAGACTTTCATGCGGGAGAGGCTACTTTTATGTGT
2241 CGTCTTCCGGGGAAGGGTCCCTCCACTGAAAGCTAGCCAGTCATGTTTTCTGTTTTTGGATTTTTGCAATTGGTTTCACC
2321 TCATGTCTCCCTCCCTACAAAGCACTGCCTCTACTGGGCGTGCTGCCAAGGCCATGTGCACTCCATCCTCATGTATCCTT
2401 TTTCACGGGGACCAGAACACTGGTACGTCATCACCAAAGCCAATCTGCTCTAGCTGCCCACAGATGCCACCAAAACCTGC
2481 TATCTCTTCATCACCAGGTACGATTCTCTTTCCACAGTGGACACAGCAGGCTATTTTCTAGTTTGTGCTGGTCACGTGGT
2561 AGATGAAGCCTCTTACTGCCCCACTTAGGGTGGCCACGGCTGCTTGTGAATGCAGCTTTGCCAGTGGCATATCTGTCATC
2641 TGATTGCGGTGGTGAAATGGAATTGAGGCCCAAGGTTAGAAGCAGCCGAGACGCCACTTGGATACTGATTTGAACAATGT
2721 AGAAGTCAGATTCTGAATTCCAAAGTTATTTCTCATAAGTACCCAATGGCATCTCTCCATCTACAAAGTTGCAGTATTAT
2801 GCAAATAAAACTGACCTCATTTTCTGCTATGCAATAAGAATACTTAATTCTAGTTCCCGACAAGCCAGTTGCAATATCCC
2881 CTAAGATGCTTTTTGAGCTGTCTTACTTTGATATCTGTTGTGTAATGTTTGTATATTTCTGAGCCAGATCCTTTCAAAGA
2961 TTGCCTTTTTATAAAATTGAAGCTATAGCTTTTAGGCTAAAATTTTAACGTAGATATTTTTATAAGATATTTTTTTCAAG
3041 AGTTTGAATCGCTTTTTATTGTCCATGATAATGAAATGTTGTGTTCTTTGCATCATTCACTCTCAAACGTAGTTCATGCC
3121 TGTAGCTCTCTTCCTTTTGTTTCTCACCCTTCAGAAACATATTTTTCAGTAGCTCCAGGTAGATGAGCCTTTTTTTTTTT
3201 TTTAAAAATACCATATTCAAGGGAGTCTGCTGAATTTTAAAACGCAGTCACTGGTGTTTCTTGAATTGCTAGGGACTGAT
3281 GTTATGTTCGACTCAGCACTTGCCCGTCTGTATTGATTGTGTCTTTTTTTTTTTTTTTGGAGTCTGCTTTCTGTGGGGGT
3361 GAGGCCGGGCTGTCTCGTGGTGGCTCCCACTGACGGGCACTGAGCCTGGTACCCTGTGGCATGGAGAAGCCTCAGGGAAA
3441 GGCCTGCCCCCCCAGCACATACTCCCATAGTGTCCTAGGTCCAGCCGACCATTCCTTATTCTCTTCTATCTCCTTGTTGA
3521 TCTGAAGCTTCCAATAGCTTGAGGCCTTTGCTGCTGGATGATGCCCTTTTTGGGAGCATCTTGTCTCTAACCTTTAAAAG
3601 AGGGGTCAATCCTCATGATCCCTGTGTGTTAAGCATATGCTTTGCAGGTGCTCACACTACACTTACAACTTGCTTCTTGA
3681 GCTATGTCTCTACTCCAGGCTCTGTTTTGTGTATTTATCTGCCATTTGCATCATGGTTTTTAAAATTTATTATTATTATT
3761 ATTATTGTTGGGACAGGTGCCATTTAAATTGCCTCCATGCTCCCCATTTGCACCTAGCTGGATCAAGTTGGGAGGCTGAG
3841 CAAACTCATATTCCAGTTAGTTGGAGTTTTTAAAGGCTCTGTTTGCCTGGAGAAGCAAGGAGGTTAGAATGTAATTTTTT
3921 TAAGCGTTTGCACTATTTAGAGTCCTAAGCCCCTCATGTTCAGCTGTGCTGTGTTTCTACTGACCAAGCAGGAGAGCCAG
4001 CAGCACTTCCAGCATTTGGGAATGGAAGAGATTTCTTCTGTAGTGGATAATTACAGCCTCATAGCCCCTGTGCAGCCTTC
4081 GTCATGGGACTCAGTGACTCATGGATATAGCATCAGCCATGGCAGGAATGCACAGGACTGTGGCATTTGCAGCATCAAAT
4161 CACCCTAGTGCCATGTTTGGTTATGAGATTGTAAATTATTCGCTCCCCCATCCTCCCCTCCCCTCATTTTCAGTGGCAAT
4241 AGAGGACCCTTGTTGTACTTCTTGTTTAATTTGCATATTATGTGTAAAATGCTTTCGTTGAAAGAAAACTGAAGACACTG
4321 AATGTGTATGTCTGTGTGGGTGCTCTGTCCCTGTGGTTGTCATAGCCAGTCAGACTTGATCACTGACACCCCGTACAACA
4401 TATTGCATAGGTAAGATCCTCGATCTGGTGTTCTCTGCGTGGCTGTTAGGGACTGTATATCTTGTAAAAGAACACTTGTC
4481 ACATGCTTGATCAGTTACAGCAATAGCTGAAGAAACATTTCCTCAAATGTATTATTTTAACAGGAATCATGTTCTAATTT
4561 CCCATCCTTTAATTTTAATAAAAGCTGAACTGTGTGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgAGAAAAGUAAUUACAUCUGu 5'
            | | | ::|  :||||||| 
Target 5' tgTGTGTGTGTGTGTGTAGACc 3'
 304 - 325 148.00 -7.90
2 
miRNA  3' cgAGAA-AAGUA--AUUACAUCUGu 5'
            | || |||||   |:|||:||| 
Target 5' ggTGTTGTTCATCGCAGTGTGGACa 3'
 143 - 167 146.00 -14.30
3 
miRNA  3' cgagaAAAGUAAUUACAUCUgu 5'
               ||| |  ||||||||  
Target 5' actgaTTTGAACAATGTAGAag 3'
 2704 - 2725 141.00 -8.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
350983 39 ClinVar
350982 108 ClinVar
350981 141 ClinVar
350980 149 ClinVar
905542 174 ClinVar
350979 224 ClinVar
350978 299 ClinVar
350976 321 ClinVar
350977 321 ClinVar
350975 481 ClinVar
350974 501 ClinVar
350973 539 ClinVar
350972 595 ClinVar
904752 681 ClinVar
350971 748 ClinVar
350970 790 ClinVar
904751 953 ClinVar
350969 1034 ClinVar
350968 1055 ClinVar
350967 1104 ClinVar
350966 1106 ClinVar
907006 1124 ClinVar
907005 1128 ClinVar
350965 1310 ClinVar
350964 1434 ClinVar
350963 1451 ClinVar
350962 1583 ClinVar
350961 1651 ClinVar
350960 1657 ClinVar
905982 1846 ClinVar
350959 1896 ClinVar
350958 1916 ClinVar
905981 1919 ClinVar
350957 2023 ClinVar
350956 2080 ClinVar
905468 2088 ClinVar
350955 2156 ClinVar
350954 2168 ClinVar
350953 2248 ClinVar
350952 2267 ClinVar
905467 2337 ClinVar
350951 2360 ClinVar
350950 2404 ClinVar
350949 2448 ClinVar
350948 2472 ClinVar
350947 2485 ClinVar
904677 2647 ClinVar
350946 2687 ClinVar
904676 2692 ClinVar
350945 2763 ClinVar
350944 2805 ClinVar
907989 2886 ClinVar
350943 2926 ClinVar
907988 2941 ClinVar
907987 2991 ClinVar
907986 3051 ClinVar
350942 3068 ClinVar
350941 3128 ClinVar
350940 3204 ClinVar
350938 3205 ClinVar
350939 3205 ClinVar
350936 3206 ClinVar
350937 3206 ClinVar
905919 3206 ClinVar
350934 3209 ClinVar
350935 3209 ClinVar
350933 3210 ClinVar
905918 3244 ClinVar
350932 3271 ClinVar
350931 3339 ClinVar
350930 3340 ClinVar
350929 3342 ClinVar
905917 3410 ClinVar
350928 3473 ClinVar
905404 3698 ClinVar
905403 3913 ClinVar
350927 3920 ClinVar
350926 4006 ClinVar
350925 4065 ClinVar
350924 4066 ClinVar
905402 4080 ClinVar
905401 4166 ClinVar
904614 4185 ClinVar
904613 4202 ClinVar
350923 4210 ClinVar
350922 4257 ClinVar
350921 4356 ClinVar
350920 4364 ClinVar
904612 4421 ClinVar
907917 4438 ClinVar
COSN31610267 37 COSMIC
COSN31541940 47 COSMIC
COSN31598452 99 COSMIC
COSN20075333 103 COSMIC
COSN30496794 115 COSMIC
COSN31525965 120 COSMIC
COSN30541264 156 COSMIC
COSN17182662 270 COSMIC
COSN20101868 295 COSMIC
COSN25982673 389 COSMIC
COSN26644004 432 COSMIC
COSN26553112 454 COSMIC
COSN31543979 686 COSMIC
COSN5590200 750 COSMIC
COSN32058761 758 COSMIC
COSN31489607 766 COSMIC
COSN26573223 846 COSMIC
COSN2072279 856 COSMIC
COSN5865637 1078 COSMIC
COSN2072278 1335 COSMIC
COSN216955 1763 COSMIC
COSN15741773 2088 COSMIC
COSN31536449 2399 COSMIC
COSN28664445 2404 COSMIC
COSN28834647 2407 COSMIC
COSN31529491 2786 COSMIC
COSN2072276 2858 COSMIC
COSN32057728 2926 COSMIC
COSN31521764 3029 COSMIC
COSN22532537 3047 COSMIC
COSN20101865 3205 COSMIC
COSN28979022 3323 COSMIC
COSN27568853 3376 COSMIC
COSN22199131 3601 COSMIC
COSN29402574 3688 COSMIC
COSN9407569 3695 COSMIC
COSN30540150 3764 COSMIC
COSN15662254 3841 COSMIC
COSN28776324 3920 COSMIC
COSN30162637 3958 COSMIC
COSN31570662 4027 COSMIC
COSN28832091 4210 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs775191089 2 dbSNP
rs754244191 3 dbSNP
rs751013066 14 dbSNP
rs780619286 20 dbSNP
rs201083393 22 dbSNP
rs751102285 24 dbSNP
rs1271037535 28 dbSNP
rs1191412618 32 dbSNP
rs1018743454 36 dbSNP
rs763816822 38 dbSNP
rs762735618 39 dbSNP
rs752537990 41 dbSNP
rs1310102331 42 dbSNP
rs765065530 45 dbSNP
rs965784227 46 dbSNP
rs201921226 48 dbSNP
rs776391980 51 dbSNP
rs1161605198 52 dbSNP
rs1007295598 59 dbSNP
rs368098288 70 dbSNP
rs935928248 71 dbSNP
rs1380353649 94 dbSNP
rs147305829 108 dbSNP
rs576720491 118 dbSNP
rs902759896 120 dbSNP
rs145643127 123 dbSNP
rs769406714 125 dbSNP
rs1312298526 130 dbSNP
rs577877283 135 dbSNP
rs189064290 141 dbSNP
rs1222815567 146 dbSNP
rs896627888 147 dbSNP
rs886059957 149 dbSNP
rs938190049 153 dbSNP
rs745422800 155 dbSNP
rs909206537 156 dbSNP
rs1182219462 158 dbSNP
rs1387184720 165 dbSNP
rs952334981 167 dbSNP
rs1158092668 170 dbSNP
rs1378746793 174 dbSNP
rs919248967 175 dbSNP
rs1253729342 178 dbSNP
rs1385314110 180 dbSNP
rs972044676 182 dbSNP
rs1049046223 183 dbSNP
rs576856604 191 dbSNP
rs966078873 201 dbSNP
rs1324859234 211 dbSNP
rs1265410409 216 dbSNP
rs555179725 219 dbSNP
rs1307136507 220 dbSNP
rs536807069 224 dbSNP
rs778510694 227 dbSNP
rs770309168 240 dbSNP
rs1261693409 241 dbSNP
rs975950761 244 dbSNP
rs953318372 249 dbSNP
rs1202359803 263 dbSNP
rs1245553605 264 dbSNP
rs1296486483 277 dbSNP
rs1384121314 280 dbSNP
rs566283531 281 dbSNP
rs547527636 284 dbSNP
rs1377153140 296 dbSNP
rs1302304151 297 dbSNP
rs1421109906 298 dbSNP
rs539132895 299 dbSNP
rs910353778 301 dbSNP
rs1364199350 307 dbSNP
rs1465397689 309 dbSNP
rs1173967518 318 dbSNP
rs1392793402 321 dbSNP
rs1408284252 321 dbSNP
rs3839339 321 dbSNP
rs765148714 321 dbSNP
rs1307213665 324 dbSNP
rs1311218049 338 dbSNP
rs1222118146 341 dbSNP
rs1406668447 355 dbSNP
rs571539969 359 dbSNP
rs1463804962 360 dbSNP
rs1198493002 361 dbSNP
rs957141816 363 dbSNP
rs1033125136 365 dbSNP
rs758854191 367 dbSNP
rs1013947730 369 dbSNP
rs895537585 374 dbSNP
rs1055937373 379 dbSNP
rs937130190 382 dbSNP
rs977072363 386 dbSNP
rs966974343 396 dbSNP
rs1170783675 399 dbSNP
rs926779508 401 dbSNP
rs1021234354 406 dbSNP
rs184295870 407 dbSNP
rs530692220 409 dbSNP
rs1463104104 428 dbSNP
rs930860838 430 dbSNP