miRTarBase - #MIRT613934


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pre-miRNA Information
pre-miRNA hsa-mir-640   
Genomic Coordinates chr19: 19435063 - 19435158
Synonyms MIRN640, hsa-mir-640, MIR640
Description Homo sapiens miR-640 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-640
Sequence 61| AUGAUCCAGGAACCUGCCUCU |81
Evidence Experimental
Experiments RT-PCR
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30153378 1 COSMIC
COSN23015356 12 COSMIC
COSN30513185 19 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs111726405 1 dbSNP
rs765622881 2 dbSNP
rs1249744889 6 dbSNP
rs752995186 12 dbSNP
rs758746736 13 dbSNP
rs918887970 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol POLR3A   
Synonyms ADDH, HLD7, RPC1, RPC155, hRPC155
Description RNA polymerase III subunit A
Transcript NM_007055   
Expression
Putative miRNA Targets on POLR3A
3'UTR of POLR3A
(miRNA target sites are highlighted)		 
>POLR3A|NM_007055|3'UTR
   1 TCCAAAGAAAGAGGGGACCATGCCTGACCTTGACTCCTTGTCCTGTCTCCAGCTGATGTATAAAGAGTTTTGTGCTCCCT
  81 GGGACGGGGGTCCTGAGGTCCCCACCTATGCCAGCAATCAGAGAAGCCCTCTTGGCATCCCCAGGAGCAGCTTCTCCTCT
 161 GATAGGGTGCAGCTCACACCAGTGACCCTGACTGTGCCACGCTGCTCGGGAGAGCTGAGGGTTTTATTGTTTGCTTGCTT
 241 GAAACCTAATCTATAGACGGCCCCACAGCTCGTGCACACACTGCTTCCCTGGACTTAAAGCCCAGCCAGGTGTCATGGTC
 321 CATCCCAGCTCACTGCATACATCCATCGGCTCCCCATGGTGTCTTCACACCTGACGATGAGCCAGGCCTGAGCCCCACAC
 401 AGGCCAGGGCACATTCTTGGATTTTCCATTCCTTGGTCATGCTGGAATCTCTCAATGTGACATACTTATGTAAATATTGT
 481 TACTATTATTTATTTGTTCCATTTGAGGGATTTGGAATTTTTGTTATTTTAGTTTTATTTTTGAAACCAAGCATCTATAG
 561 AAACCAAGAAAGTCAGCATGTAAGCGTCACTGGAAAAACTGGTTTAAGCAAATAGAGCCGTCTGGGATTTGTAACTGAGG
 641 TGCAACTGTCATGAGGCCCAGGCAGCTCTGTAACATCTTCTATAGATGCCCCTGGCTACCCTGTTGTTTTCATCTACCTC
 721 AGACCCCTATCATGGGGCTCTACCCTGTGACAAGAGCCAAACCCATTCTCCATGGCCTATGGAAGCCTCACTGGAGTTTG
 801 GGGCCTGCTGCAATGGGGATGAGATGGTTTTTTGTAGAATTATACTTACGTTCCTTGGATGATCTCTAGTTGATTTTTTA
 881 AGTTCTGAGTTGATGCTGTTAAGGTACCCGGGGTAGCCATTGGTTCTTGGATCTGTGTTAGAATGAGTGCTTTCCCTTCC
 961 TACTGATGTGATTGTGGATTAGGAATTCGTGACCGAGTGATTTTTGGCCAGTGGTTGGGTTTAAAATTCTATTAAAATTT
1041 GTAGTTTGGGCTGGGTGCTGTGGCTCATACCTATAATCCCAGCACTTTGGGAGGCCGAGGGGGGCAGATCACTTGAGCCC
1121 AGGAGTTCGAGAGCAGCCTGGGCAACATGACGAAACCCCGTCTCTACAGAGAATACAAAAATTAGCCAGGCATGGTGGCC
1201 CATGCCTGTAGTACCTGCTATTGGTAAGGCTGAGGTGGAAGGTTCACTTGAGCCTGGGAGGTGGAGGTTGTAGTGAGCCA
1281 AGATCGTGCCACTACACTCCAGCCTGGGCAACAAAGCAAGACCTTGTCTCAAAAAAAAAAAAGAAAAAAATTAAGCGTAA
1361 AAAAAAATTAGTTTTTATAAAAAATTATAGTTTGACCTTTTGATTTCCCTGCATCTACAAGGTAGACCTATTAACTTCTC
1441 TTGGGGTATCAGTGATGTGGAAAAAAAATGCCATTTTTCTTAATGTTTAACCCCCCTTTATCTTTGAATTGAGCTAGAGC
1521 CTGGTTTAGGACAAAGGATTAAGTTTGTTAATGAACACTAATTCAGGGCTTCTACTTGAGACCCCACCGAGATCACCAGT
1601 TCTCATGTAACCTGGGAAGAGCCATAAAGGGGTACCCCCCACCCCAACTGCCTTCCTGGAAGCATGCCTGGGAAGTAAGC
1681 TGTAGGCCTGATCCGAGCCAGGACCACTGGGATCCGTGCAAAGGCCAGGGGAGGGTAGAATTGAATCATAGGAGTGAACT
1761 CCGGCACCTGTTGTCTTCTGCGGGTGACGCACACTTTAAATGGAAGAGAGGTTGTGGCTATAACTTGTGGCTGGGAATAA
1841 TAAAGATGGCACCGCCAAGGAGCCTCACCTTGCGTGAGTGAGTACTCAGTTGGGCGCTGCAGGGTCTGGAGTCTGTGTGA
1921 GACGTGTGTGATTGTGATGGGTGCGAATCAGCGTATAGCACTTGAGAACAAGGCAGACCTTGGAGCAGAATGGTTATGTG
2001 AAGGATCACATCACCCATGGGTAGGGGGGGAAGTCATACGTCCTGGAGGTGCTGGTCCTCCTCCTGGAACTGCCAGCCTT
2081 GCTAGGACTATCAACATCAACAGCATTGCCTGGTAAACCCTACTGTTTGTGCTCCCCACTGTGTCCCATGACTGGTGTTA
2161 AAATTCTCCCTACTTTGATCATCTGCCCTGCCCAGGCCTTGGGCTTTATGCCAGCACAGAGCTCAAAGGCCAGGTAGCAG
2241 CACATCCTCAAGCATGAGAGCTCAAAGGGTTACATTTGAGTCTCTGTACCTGCTTGGAAGAAATAAAAATACGTGTGAAT
2321 TCCATCTCAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucUCCGU--CCAAGGACCUAGua 5'
            || ||  |||||:||||||  
Target 5' gtAGCCATTGGTTCTTGGATCtg 3'
 913 - 935 153.00 -18.30
2 
miRNA  3' ucUCCGUCCAAGGACCUAGua 5'
            :||||  |||:|||||:  
Target 5' caGGGCACATTCTTGGATTtt 3'
 405 - 425 135.00 -16.80
3 
miRNA  3' ucuCCGUCCAAGGACCUAGUa 5'
             | :: | |: |||||:| 
Target 5' actGATGTGATTGTGGATTAg 3'
 962 - 982 130.00 -6.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
549564 18 ClinVar
301032 90 ClinVar
301031 135 ClinVar
301030 136 ClinVar
880079 150 ClinVar
880078 201 ClinVar
301028 272 ClinVar
301029 272 ClinVar
880077 303 ClinVar
880076 308 ClinVar
880075 339 ClinVar
880074 344 ClinVar
301027 345 ClinVar
301026 426 ClinVar
301025 469 ClinVar
301024 470 ClinVar
878865 586 ClinVar
301023 620 ClinVar
878864 671 ClinVar
301022 673 ClinVar
301021 690 ClinVar
301020 813 ClinVar
878262 818 ClinVar
301019 883 ClinVar
878261 910 ClinVar
301018 920 ClinVar
878260 923 ClinVar
301017 936 ClinVar
301016 989 ClinVar
877222 994 ClinVar
301015 1015 ClinVar
877221 1097 ClinVar
301014 1100 ClinVar
877220 1129 ClinVar
877219 1152 ClinVar
301013 1159 ClinVar
301012 1207 ClinVar
301011 1219 ClinVar
301010 1303 ClinVar
301009 1323 ClinVar
880020 1335 ClinVar
880019 1339 ClinVar
880018 1341 ClinVar
880017 1342 ClinVar
301008 1343 ClinVar
301007 1448 ClinVar
879653 1457 ClinVar
301006 1461 ClinVar
879652 1564 ClinVar
301005 1569 ClinVar
879651 1585 ClinVar
301004 1589 ClinVar
879650 1607 ClinVar
301003 1641 ClinVar
879649 1643 ClinVar
301002 1680 ClinVar
301001 1695 ClinVar
301000 1718 ClinVar
300999 1763 ClinVar
300998 1781 ClinVar
300997 1782 ClinVar
300996 1825 ClinVar
300995 1853 ClinVar
300994 1862 ClinVar
300993 1867 ClinVar
300992 1869 ClinVar
300991 1873 ClinVar
300990 1924 ClinVar
300989 1945 ClinVar
300987 1953 ClinVar
300988 1953 ClinVar
300986 1965 ClinVar
300985 2039 ClinVar
300984 2073 ClinVar
300983 2134 ClinVar
300982 2190 ClinVar
300981 2205 ClinVar
COSN30525409 7 COSMIC
COSN31511474 15 COSMIC
COSN5253958 16 COSMIC
COSN31503031 19 COSMIC
COSN31563201 23 COSMIC
COSN30458292 47 COSMIC
COSN31612376 111 COSMIC
COSN31592557 128 COSMIC
COSN30152168 161 COSMIC
COSN8189859 258 COSMIC
COSN32062540 586 COSMIC
COSN22779294 639 COSMIC
COSN8721466 648 COSMIC
COSN8721465 917 COSMIC
COSN29573222 1343 COSMIC
COSN32085181 1874 COSMIC
COSN31960504 1895 COSMIC
COSN8189858 2025 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1372135242 7 dbSNP
rs1186194596 16 dbSNP
rs756517107 17 dbSNP
rs1248039821 18 dbSNP
rs995543110 19 dbSNP
rs1440586994 25 dbSNP
rs781209023 29 dbSNP
rs907845711 31 dbSNP
rs1219565107 34 dbSNP
rs1346047291 38 dbSNP
rs755213507 39 dbSNP
rs983478981 41 dbSNP
rs368142672 43 dbSNP
rs952090251 45 dbSNP
rs1321257582 49 dbSNP
rs1447997360 50 dbSNP
rs766558303 51 dbSNP
rs1023874713 54 dbSNP
rs1470039911 57 dbSNP
rs1156331078 60 dbSNP
rs773836186 62 dbSNP
rs1012335882 65 dbSNP
rs896661034 68 dbSNP
rs1392714246 71 dbSNP
rs1335746909 77 dbSNP
rs371896851 85 dbSNP
rs1175047416 86 dbSNP
rs1433634897 89 dbSNP
rs146055367 90 dbSNP
rs1335129204 93 dbSNP
rs963878119 98 dbSNP
rs1236733615 99 dbSNP
rs1277867631 100 dbSNP
rs1325836378 105 dbSNP
rs375589784 124 dbSNP
rs1262809661 125 dbSNP
rs1460126429 126 dbSNP
rs531659725 135 dbSNP
rs568729735 136 dbSNP
rs947114143 142 dbSNP
rs1180205110 143 dbSNP
rs891055829 148 dbSNP
rs774061285 160 dbSNP
rs1052039939 167 dbSNP
rs999173149 172 dbSNP
rs552213589 175 dbSNP
rs1175055503 187 dbSNP
rs975338180 192 dbSNP
rs1463161567 194 dbSNP
rs903600691 196 dbSNP
rs532200751 200 dbSNP
rs180866130 201 dbSNP
rs1389458073 206 dbSNP
rs540369827 207 dbSNP
rs547189466 208 dbSNP
rs1235127255 211 dbSNP
rs1056658805 219 dbSNP
rs562337982 220 dbSNP
rs939568896 221 dbSNP
rs908147427 227 dbSNP
rs986677502 233 dbSNP
rs951526620 248 dbSNP
rs983447978 249 dbSNP
rs12264652 251 dbSNP
rs747495009 252 dbSNP
rs974471203 258 dbSNP
rs920599516 259 dbSNP
rs962692713 266 dbSNP
rs1312719973 271 dbSNP
rs2241547 272 dbSNP
rs576687215 280 dbSNP
rs772281716 283 dbSNP
rs746104527 284 dbSNP
rs1372132777 285 dbSNP
rs965176344 289 dbSNP
rs1373244366 308 dbSNP
rs1165207214 311 dbSNP
rs1366148726 324 dbSNP
rs896630021 328 dbSNP
rs1035585270 329 dbSNP
rs1365503165 334 dbSNP
rs142880941 339 dbSNP
rs1296629491 342 dbSNP
rs545793119 344 dbSNP
rs74538796 345 dbSNP
rs1030918374 347 dbSNP
rs553839333 348 dbSNP
rs534589535 375 dbSNP
rs903477663 376 dbSNP
rs892811246 383 dbSNP
rs1260657625 385 dbSNP
rs1022395185 392 dbSNP
rs1011968355 393 dbSNP
rs1426327264 396 dbSNP
rs894915529 410 dbSNP
rs1056627398 413 dbSNP
rs1185225317 426 dbSNP
rs76696077 426 dbSNP
rs942578914 441 dbSNP
rs1161672330 442 dbSNP
rs187985904 451 dbSNP
rs756096581 460 dbSNP
rs1289489357 461 dbSNP
rs1327653581 462 dbSNP
rs537710372 463 dbSNP
rs1361562183 468 dbSNP
rs567251074 469 dbSNP
rs74704054 470 dbSNP
rs1383900731 480 dbSNP
rs1292991133 500 dbSNP
rs918630997 509 dbSNP
rs1231861311 521 dbSNP
rs1215928999 523 dbSNP
rs974187612 532 dbSNP
rs1314365317 537 dbSNP
rs1484698480 543 dbSNP
rs920584052 558 dbSNP
rs532136707 575 dbSNP
rs1243377246 581 dbSNP
rs767378931 585 dbSNP
rs759187201 586 dbSNP
rs1383600056 600 dbSNP
rs916594387 607 dbSNP
rs1286680265 612 dbSNP
rs1455222054 619 dbSNP
rs184043149 620 dbSNP
rs912002242 623 dbSNP
rs960927342 626 dbSNP
rs1452420671 632 dbSNP
rs1282747874 635 dbSNP
rs1474119489 642 dbSNP
rs1419807551 657 dbSNP
rs1305684364 658 dbSNP
rs766200988 660 dbSNP
rs1035318893 661 dbSNP
rs150842225 673 dbSNP
rs191565691 682 dbSNP
rs1030802108 687 dbSNP
rs1460573831 688 dbSNP
rs74451934 690 dbSNP
rs761273372 691 dbSNP
rs1480925135 711 dbSNP
rs1021947095 712 dbSNP
rs1012348583 714 dbSNP
rs758359572 718 dbSNP
rs1212168641 720 dbSNP
rs1337371122 725 dbSNP
rs892917777 729 dbSNP
rs1469441186 732 dbSNP
rs1332626957 733 dbSNP
rs1356575719 738 dbSNP
rs1443386122 740 dbSNP
rs1173117882 745 dbSNP
rs1349156031 765 dbSNP
rs1245058724 771 dbSNP
rs1224857144 772 dbSNP
rs1034801424 779 dbSNP
rs750579121 807 dbSNP
rs1006598912 811 dbSNP
rs186927032 813 dbSNP
rs886567389 816 dbSNP
rs185309450 818 dbSNP
rs1389235585 828 dbSNP
rs918445501 832 dbSNP
rs1203540920 835 dbSNP
rs1249579942 840 dbSNP
rs746272267 842 dbSNP
rs774776960 844 dbSNP
rs1201714468 848 dbSNP
rs757619409 849 dbSNP
rs1459853865 850 dbSNP
rs1039018240 855 dbSNP
rs562837125 860 dbSNP
rs1171111595 861 dbSNP
rs369531611 863 dbSNP
rs941437020 867 dbSNP
rs916687631 875 dbSNP
rs868574928 879 dbSNP
rs1170144576 880 dbSNP
rs1369274240 882 dbSNP
rs113075575 883 dbSNP
rs987485178 895 dbSNP
rs934761813 896 dbSNP
rs923745392 909 dbSNP
rs960729923 910 dbSNP
rs978357038 912 dbSNP
rs1271629290 914 dbSNP
rs967972026 916 dbSNP
rs1450206397 919 dbSNP
rs77590844 920 dbSNP
rs978371466 922 dbSNP
rs990499323 923 dbSNP
rs1223051201 927 dbSNP
rs11002352 933 dbSNP
rs560141767 936 dbSNP
rs1451170036 937 dbSNP
rs1192292208 939 dbSNP
rs1196822667 949 dbSNP
rs1244100605 956 dbSNP
rs540339471 966 dbSNP
rs1475839179 972 dbSNP
rs1188348720 977 dbSNP
rs967259008 980 dbSNP
rs1022476463 982 dbSNP
rs376110690 988 dbSNP
rs570095005 989 dbSNP
rs1403145337 993 dbSNP
rs148339082 994 dbSNP
rs551589666 995 dbSNP
rs886047282 1015 dbSNP
rs761102062 1018 dbSNP
rs950465023 1023 dbSNP
rs1295138085 1046 dbSNP
rs1029969964 1050 dbSNP
rs1246427689 1060 dbSNP
rs994110679 1066 dbSNP
rs1026466016 1069 dbSNP
rs1249290692 1071 dbSNP
rs995442183 1097 dbSNP
rs554422633 1099 dbSNP
rs886047281 1100 dbSNP
rs1365260835 1101 dbSNP
rs895227830 1102 dbSNP
rs1438621002 1103 dbSNP
rs1368436723 1105 dbSNP
rs1472068050 1110 dbSNP
rs1055145992 1111 dbSNP
rs939318675 1112 dbSNP
rs756147766 1125 dbSNP
rs928008172 1128 dbSNP
rs1323901501 1129 dbSNP
rs978723238 1133 dbSNP
rs1039730508 1136 dbSNP
rs1390631894 1137 dbSNP
rs1281352572 1141 dbSNP
rs945627822 1147 dbSNP
rs748122991 1151 dbSNP
rs143418325 1152 dbSNP
rs886047280 1159 dbSNP
rs890418976 1160 dbSNP
rs193104439 1168 dbSNP
rs1441196815 1170 dbSNP
rs934729151 1171 dbSNP
rs1364863629 1176 dbSNP
rs780933790 1178 dbSNP
rs1472005210 1179 dbSNP
rs1156272387 1185 dbSNP
rs924729032 1187 dbSNP
rs1017997612 1191 dbSNP
rs1302065779 1192 dbSNP
rs886047279 1207 dbSNP
rs1392916904 1213 dbSNP
rs754930909 1219 dbSNP
rs946582579 1226 dbSNP
rs751349983 1228 dbSNP
rs558875685 1238 dbSNP
rs1325943493 1246 dbSNP
rs959289427 1255 dbSNP
rs1181485769 1258 dbSNP
rs1197898784 1261 dbSNP
rs994262965 1267 dbSNP
rs1436399946 1281 dbSNP
rs1482990030 1285 dbSNP
rs927591034 1286 dbSNP
rs1270348025 1289 dbSNP
rs1480564471 1292 dbSNP
rs1175001331 1294 dbSNP
rs981796662 1297 dbSNP
rs188968443 1303 dbSNP
rs894986295 1304 dbSNP
rs1369910453 1312 dbSNP
rs1231458264 1322 dbSNP
rs45570840 1323 dbSNP
rs1347538632 1327 dbSNP
rs1275402637 1330 dbSNP
rs1026516033 1332 dbSNP
rs939466876 1335 dbSNP
rs183880409 1339 dbSNP
rs1042386795 1343 dbSNP
rs140070093 1343 dbSNP
rs550821263 1343 dbSNP
rs56144624 1343 dbSNP
rs945401472 1343 dbSNP
rs1190102591 1346 dbSNP
rs915460659 1356 dbSNP
rs535928183 1357 dbSNP
rs1389248921 1359 dbSNP
rs1017777323 1365 dbSNP
rs1165456059 1368 dbSNP
rs910735928 1368 dbSNP
rs1375081094 1373 dbSNP
rs1311085511 1376 dbSNP
rs1366085830 1379 dbSNP
rs1458509325 1381 dbSNP
rs1416271322 1385 dbSNP
rs1292971021 1386 dbSNP
rs567356433 1388 dbSNP
rs1384076257 1390 dbSNP
rs1298809716 1396 dbSNP
rs955132947 1402 dbSNP
rs528712468 1410 dbSNP
rs758144618 1411 dbSNP
rs1226636735 1418 dbSNP
rs1007744834 1424 dbSNP
rs1360758559 1430 dbSNP
rs890733440 1442 dbSNP
rs1365909945 1443 dbSNP
rs550447264 1446 dbSNP
rs78703311 1448 dbSNP
rs1256396216 1450 dbSNP
rs562775653 1457 dbSNP
rs552431215 1459 dbSNP
rs3088264 1461 dbSNP
rs759036938 1461 dbSNP
rs915030083 1465 dbSNP
rs1033463636 1469 dbSNP
rs959172884 1469 dbSNP
rs1455411083 1471 dbSNP
rs1054984655 1472 dbSNP
rs1003823214 1479 dbSNP
rs1388157261 1491 dbSNP
rs190828434 1495 dbSNP
rs1339061447 1497 dbSNP
rs1380558611 1497 dbSNP
rs1042872258 1503 dbSNP
rs1289918859 1507 dbSNP
rs1318259984 1511 dbSNP
rs1228448494 1512 dbSNP
rs776187554 1517 dbSNP
rs893829725 1528 dbSNP
rs1054011861 1531 dbSNP
rs1243462195 1535 dbSNP
rs762341253 1543 dbSNP
rs1355010937 1556 dbSNP
rs1291636167 1558 dbSNP
rs540625875 1564 dbSNP
rs886047278 1569 dbSNP
rs1410058022 1573 dbSNP
rs1421010824 1575 dbSNP
rs1359800118 1576 dbSNP
rs574787592 1581 dbSNP
rs981764155 1585 dbSNP
rs16935486 1589 dbSNP
rs760061298 1607 dbSNP
rs1391489272 1622 dbSNP
rs933519645 1623 dbSNP
rs1175114076 1628 dbSNP
rs1376127275 1635 dbSNP
rs990829452 1639 dbSNP
rs1287103741 1641 dbSNP
rs886047277 1641 dbSNP
rs544414095 1643 dbSNP
rs922343084 1644 dbSNP
rs972897855 1651 dbSNP
rs1475103830 1657 dbSNP
rs1416200822 1662 dbSNP
rs774751433 1663 dbSNP
rs772780553 1665 dbSNP
rs909567042 1668 dbSNP
rs80022412 1680 dbSNP
rs1471736915 1682 dbSNP
rs1214470402 1687 dbSNP
rs1201937828 1691 dbSNP
rs558812074 1694 dbSNP
rs61152426 1695 dbSNP
rs1174346996 1696 dbSNP
rs1356809915 1703 dbSNP
rs1306872521 1705 dbSNP
rs1269970308 1706 dbSNP
rs1348154994 1709 dbSNP
rs1003341773 1714 dbSNP
rs573185644 1715 dbSNP
rs796910846 1716 dbSNP
rs1217300033 1717 dbSNP
rs144088118 1718 dbSNP
rs999066082 1720 dbSNP
rs1204271292 1726 dbSNP
rs41274598 1734 dbSNP
rs1482142705 1738 dbSNP
rs893922831 1741 dbSNP
rs1053768852 1749 dbSNP
rs1428750915 1751 dbSNP
rs1021640502 1752 dbSNP
rs1477792635 1756 dbSNP
rs1012050682 1759 dbSNP
rs894582463 1762 dbSNP
rs4979935 1763 dbSNP
rs937860672 1771 dbSNP
rs1168580907 1774 dbSNP
rs889363354 1777 dbSNP
rs1323604522 1781 dbSNP
rs529607825 1781 dbSNP
rs11817392 1782 dbSNP
rs1461427079 1784 dbSNP
rs562406479 1785 dbSNP
rs1046305770 1788 dbSNP
rs929214022 1789 dbSNP
rs1167436563 1794 dbSNP
rs1406679843 1797 dbSNP
rs1365746577 1806 dbSNP
rs886047276 1825 dbSNP
rs1227367567 1829 dbSNP
rs1295366862 1831 dbSNP
rs542602364 1832 dbSNP
rs1240274819 1836 dbSNP
rs1361453601 1844 dbSNP
rs1414093499 1845 dbSNP
rs550631807 1847 dbSNP
rs1447094705 1852 dbSNP
rs11002351 1853 dbSNP
rs186668915 1854 dbSNP
rs12572507 1862 dbSNP
rs1388897739 1863 dbSNP
rs137945349 1867 dbSNP
rs547020650 1868 dbSNP
rs886047275 1869 dbSNP
rs886047274 1873 dbSNP
rs986261398 1874 dbSNP
rs959037407 1876 dbSNP
rs530090478 1878 dbSNP
rs954838362 1879 dbSNP
rs1434132829 1884 dbSNP
rs1318238498 1890 dbSNP
rs1030466344 1895 dbSNP
rs982455098 1896 dbSNP
rs1283518377 1911 dbSNP
rs1344384874 1913 dbSNP
rs1355797797 1915 dbSNP
rs1270300051 1916 dbSNP
rs561154867 1916 dbSNP
rs746845448 1923 dbSNP
rs146925988 1924 dbSNP
rs1208524418 1940 dbSNP
rs1440818146 1941 dbSNP
rs1369443219 1944 dbSNP
rs886047273 1945 dbSNP
rs1237398831 1949 dbSNP
rs1471546167 1952 dbSNP
rs141086010 1953 dbSNP
rs1456326662 1955 dbSNP
rs1437664169 1956 dbSNP
rs1354356172 1959 dbSNP
rs1169284084 1960 dbSNP
rs1408108146 1962 dbSNP
rs2241546 1965 dbSNP
rs1333480843 1978 dbSNP
rs1034472238 1989 dbSNP
rs1391477524 1996 dbSNP
rs1007531980 1997 dbSNP
rs889124633 1998 dbSNP
rs1030560823 2000 dbSNP
rs1330103333 2006 dbSNP
rs1002959334 2015 dbSNP
rs1227946306 2023 dbSNP
rs543289361 2024 dbSNP
rs750111274 2025 dbSNP
rs1046274160 2026 dbSNP
rs1251820833 2030 dbSNP
rs1036921073 2031 dbSNP
rs1471973622 2031 dbSNP
rs35772574 2031 dbSNP
rs929188402 2031 dbSNP
rs897772825 2032 dbSNP
rs1400013203 2033 dbSNP
rs1431491811 2036 dbSNP
rs182178080 2038 dbSNP
rs114774764 2039 dbSNP
rs941747422 2040 dbSNP
rs926293483 2043 dbSNP
rs910213909 2045 dbSNP
rs981828278 2048 dbSNP
rs1333009840 2049 dbSNP
rs765036875 2055 dbSNP
rs1028931702 2056 dbSNP
rs913858369 2057 dbSNP
rs1343498844 2060 dbSNP
rs1207999168 2064 dbSNP
rs1484199344 2065 dbSNP
rs779191872 2067 dbSNP
rs1233683956 2068 dbSNP
rs1482469264 2069 dbSNP
rs756926484 2073 dbSNP
rs1269064883 2074 dbSNP
rs190371858 2085 dbSNP
rs1304007143 2089 dbSNP
rs933085145 2090 dbSNP
rs1220358989 2095 dbSNP
rs1375658741 2120 dbSNP
rs1451094051 2124 dbSNP
rs372763724 2133 dbSNP
rs753333424 2134 dbSNP
rs1429236793 2148 dbSNP
rs145516401 2153 dbSNP
rs1296473961 2169 dbSNP
rs1296876775 2172 dbSNP
rs968020823 2177 dbSNP
rs1407539996 2179 dbSNP
rs1372036179 2182 dbSNP
rs1387498622 2186 dbSNP
rs886047272 2190 dbSNP
rs34076253 2201 dbSNP
rs763641587 2203 dbSNP
rs759985023 2205 dbSNP
rs774802742 2213 dbSNP
rs766736149 2216 dbSNP
rs1231039315 2220 dbSNP
rs986226642 2221 dbSNP
rs576637829 2227 dbSNP
rs1225575484 2235 dbSNP
rs763247235 2238 dbSNP
rs1030727484 2247 dbSNP
rs990552923 2252 dbSNP
rs898061814 2256 dbSNP
rs1433763711 2268 dbSNP
rs1188932968 2275 dbSNP
rs1406979356 2288 dbSNP
rs185660125 2297 dbSNP
rs773553000 2312 dbSNP
rs1484129128 2313 dbSNP
rs1002928051 2315 dbSNP
rs887961786 2327 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084082. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucUCCGUCCAAGGACCUAGUa 5'
            ||||: |    ||||||| 
Target 5' --AGGCGAG----UGGAUCAc 3'
 		1 - 15
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084082
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep2_SigmaAb
Location of target site ENST00000372371.3 | 3UTR | AGGCGAGUGGAUCACCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.527 4.1e-3 0.425 1.9e-2 24 Click to see details
GSE19536 Breast cancer 0.255 5.2e-3 0.218 1.5e-2 100 Click to see details
GSE19783 ER+ ER+ breast cancer 0.467 1.9e-2 0.322 8.3e-2 20 Click to see details
GSE26953 Aortic valvular endothelial cells 0.393 2.9e-2 0.363 4.1e-2 24 Click to see details
GSE28260 Renal cortex and medulla 0.502 4.0e-2 0.565 2.2e-2 13 Click to see details
GSE21849 B cell lymphoma -0.292 6.2e-2 -0.208 1.4e-1 29 Click to see details
GSE19783 ER- ER- breast cancer 0.154 8.8e-2 0.184 5.2e-2 79 Click to see details
GSE42095 Differentiated embryonic stem cells 0.251 1.2e-1 0.000 5.0e-1 23 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.198 1.7e-1 0.393 2.6e-2 25 Click to see details
GSE14794 Lymphoblastoid cells -0.099 1.8e-1 -0.110 1.5e-1 90 Click to see details
GSE27834 Pluripotent stem cells -0.228 2.0e-1 -0.206 2.2e-1 16 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.161 2.5e-1 0.325 8.1e-2 20 Click to see details
GSE21687 Ependynoma primary tumors -0.078 2.7e-1 0.126 1.6e-1 64 Click to see details
GSE19350 CNS germ cell tumors -0.171 3.0e-1 -0.042 4.5e-1 12 Click to see details
GSE38226 Liver fibrosis 0.06 4.0e-1 -0.175 2.2e-1 21 Click to see details
GSE17306 Multiple myeloma -0.019 4.5e-1 0.168 1.2e-1 49 Click to see details
GSE32688 Pancreatic cancer 0.016 4.7e-1 -0.058 3.8e-1 32 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.015 4.7e-1 0.054 4.0e-1 25 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.015 4.7e-1 0.054 4.0e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
194 hsa-miR-640 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT097121 TNPO1 transportin 1 2 2
MIRT115090 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 4
MIRT204603 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT204634 MOB4 MOB family member 4, phocein 2 8
MIRT344451 MTRNR2L1 MT-RNR2-like 1 2 2
MIRT405772 EIF5 eukaryotic translation initiation factor 5 2 2
MIRT445876 SENP6 SUMO1/sentrin specific peptidase 6 2 2
MIRT497418 FAM46A family with sequence similarity 46 member A 2 2
MIRT504394 HMX2 H6 family homeobox 2 2 4
MIRT504691 SLCO2B1 solute carrier organic anion transporter family member 2B1 2 8
MIRT512386 MTRNR2L3 MT-RNR2-like 3 2 6
MIRT513003 MAN1A2 mannosidase alpha class 1A member 2 2 2
MIRT513084 USP9X ubiquitin specific peptidase 9, X-linked 2 2
MIRT519122 ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2 2
MIRT523836 F2RL1 F2R like trypsin receptor 1 2 2
MIRT565356 TMCC1 transmembrane and coiled-coil domain family 1 2 2
MIRT575895 Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 2 3
MIRT576894 Poteg POTE ankyrin domain family, member G 2 2
MIRT613780 RPS6 ribosomal protein S6 2 2
MIRT613934 POLR3A RNA polymerase III subunit A 2 2
MIRT614348 LOH12CR1 BLOC-1 related complex subunit 5 2 2
MIRT614534 NOA1 nitric oxide associated 1 2 2
MIRT617019 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT618247 MANEAL mannosidase endo-alpha like 2 2
MIRT619051 TTC4 tetratricopeptide repeat domain 4 2 2
MIRT619442 ZNF517 zinc finger protein 517 2 2
MIRT619723 FPR2 formyl peptide receptor 2 2 2
MIRT620179 TRIM72 tripartite motif containing 72 2 2
MIRT620370 ANKRD62 ankyrin repeat domain 62 2 2
MIRT621263 RTN2 reticulon 2 2 2
MIRT621463 APOH apolipoprotein H 2 2
MIRT621571 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT621683 TSPYL1 TSPY like 1 2 2
MIRT622866 PDE7A phosphodiesterase 7A 2 2
MIRT624669 ARHGEF39 Rho guanine nucleotide exchange factor 39 2 2
MIRT625607 ZNF84 zinc finger protein 84 2 2
MIRT626111 IL23R interleukin 23 receptor 2 2
MIRT628380 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 2 2
MIRT628553 MELK maternal embryonic leucine zipper kinase 2 2
MIRT628671 C2orf72 chromosome 2 open reading frame 72 2 2
MIRT628747 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT628776 TMEM154 transmembrane protein 154 2 2
MIRT628918 ZNF430 zinc finger protein 430 2 2
MIRT629174 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT629209 C12orf66 chromosome 12 open reading frame 66 2 2
MIRT629267 SLC5A8 solute carrier family 5 member 8 2 2
MIRT629498 AS3MT arsenite methyltransferase 2 2
MIRT629665 USP1 ubiquitin specific peptidase 1 2 2
MIRT629760 STK25 serine/threonine kinase 25 2 2
MIRT630899 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT631105 SLC15A2 solute carrier family 15 member 2 2 2
MIRT631112 ATCAY ATCAY, caytaxin 2 2
MIRT631450 DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 2 2
MIRT631505 FFAR4 free fatty acid receptor 4 2 2
MIRT631580 ITGAL integrin subunit alpha L 2 2
MIRT631836 CMBL carboxymethylenebutenolidase homolog 2 2
MIRT632342 SWSAP1 SWIM-type zinc finger 7 associated protein 1 2 2
MIRT633214 ZNF584 zinc finger protein 584 2 2
MIRT633223 ZNF43 zinc finger protein 43 2 2
MIRT633480 ARIH2OS ariadne RBR E3 ubiquitin protein ligase 2 opposite strand 2 2
MIRT633511 LRRC27 leucine rich repeat containing 27 2 2
MIRT633615 CWF19L1 CWF19 like 1, cell cycle control (S. pombe) 2 2
MIRT633652 SLC28A1 solute carrier family 28 member 1 2 2
MIRT633677 ZNF576 zinc finger protein 576 2 2
MIRT634196 TMOD2 tropomodulin 2 2 4
MIRT634388 PLSCR1 phospholipid scramblase 1 2 2
MIRT635817 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT635962 TTC31 tetratricopeptide repeat domain 31 2 2
MIRT636114 YPEL1 yippee like 1 2 2
MIRT636164 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT636768 CLUAP1 clusterin associated protein 1 2 2
MIRT637092 CXorf23 BCLAF1 and THRAP3 family member 3 2 2
MIRT637316 FAM9B family with sequence similarity 9 member B 2 2
MIRT637540 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT637628 ZNF431 zinc finger protein 431 2 2
MIRT637826 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT637945 IVD isovaleryl-CoA dehydrogenase 2 2
MIRT637968 IRF1 interferon regulatory factor 1 2 2
MIRT638321 RNF11 ring finger protein 11 2 2
MIRT638386 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT639244 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT642608 APOPT1 apoptogenic 1, mitochondrial 2 2
MIRT642793 SLC1A5 solute carrier family 1 member 5 2 2
MIRT643847 LACTB lactamase beta 2 4
MIRT644705 ZNF321P zinc finger protein 321, pseudogene 2 2
MIRT645148 DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 2 3
MIRT646671 CCDC69 coiled-coil domain containing 69 2 2
MIRT647780 ASB8 ankyrin repeat and SOCS box containing 8 2 2
MIRT648554 WDR92 WD repeat domain 92 2 2
MIRT648990 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT649099 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 2
MIRT650141 ZNF426 zinc finger protein 426 2 2
MIRT650791 GSR glutathione-disulfide reductase 2 2
MIRT654967 PLEKHA2 pleckstrin homology domain containing A2 2 2
MIRT655099 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT655516 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 2
MIRT656289 METTL14 methyltransferase like 14 2 2
MIRT656497 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT657074 JPH2 junctophilin 2 2 2
MIRT657314 HOOK3 hook microtubule tethering protein 3 2 2
MIRT657419 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 2 4
MIRT659032 DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2 2
MIRT659535 CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2 2
MIRT661532 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT662029 FUT2 fucosyltransferase 2 2 2
MIRT663206 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT663357 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT663557 CCR6 C-C motif chemokine receptor 6 2 2
MIRT663650 POLM DNA polymerase mu 2 2
MIRT663694 ABHD17B abhydrolase domain containing 17B 2 2
MIRT664370 CYB5A cytochrome b5 type A 2 2
MIRT664783 LIAS lipoic acid synthetase 2 4
MIRT665561 TXNL1 thioredoxin like 1 2 2
MIRT665950 TAOK1 TAO kinase 1 2 2
MIRT667338 MSANTD3 Myb/SANT DNA binding domain containing 3 2 2
MIRT667804 ITIH5 inter-alpha-trypsin inhibitor heavy chain family member 5 2 2
MIRT668804 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT669470 ARPC2 actin related protein 2/3 complex subunit 2 2 2
MIRT669599 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT669806 STOML1 stomatin like 1 2 2
MIRT669944 FBXL2 F-box and leucine rich repeat protein 2 2 2
MIRT670292 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT670381 EMP2 epithelial membrane protein 2 2 2
MIRT670481 DCUN1D2 defective in cullin neddylation 1 domain containing 2 2 2
MIRT670531 KIF1C kinesin family member 1C 2 4
MIRT670565 GLTP glycolipid transfer protein 2 2
MIRT670603 NPHP1 nephrocystin 1 2 2
MIRT670880 CYTIP cytohesin 1 interacting protein 2 2
MIRT670931 LIPG lipase G, endothelial type 2 2
MIRT671261 MTRNR2L5 MT-RNR2-like 5 2 2
MIRT671794 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT671897 GBP4 guanylate binding protein 4 2 2
MIRT672000 SLC35F6 solute carrier family 35 member F6 2 4
MIRT672074 KIR3DX1 killer cell immunoglobulin like receptor, three Ig domains X1 2 2
MIRT672319 C9orf3 chromosome 9 open reading frame 3 2 2
MIRT672853 C22orf29 retrotransposon Gag like 10 2 2
MIRT673395 WNT7B Wnt family member 7B 2 2
MIRT673537 DEGS1 delta 4-desaturase, sphingolipid 1 2 2
MIRT674285 ZNF724P zinc finger protein 724 2 2
MIRT674494 TIRAP TIR domain containing adaptor protein 2 2
MIRT675460 NUBPL nucleotide binding protein like 2 2
MIRT675569 TRIP11 thyroid hormone receptor interactor 11 2 2
MIRT676068 TIMM50 translocase of inner mitochondrial membrane 50 2 2
MIRT676254 PBOV1 prostate and breast cancer overexpressed 1 2 2
MIRT676377 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT676758 SNX2 sorting nexin 2 2 2
MIRT676773 NPHS1 NPHS1, nephrin 2 2
MIRT676874 ENSA endosulfine alpha 2 2
MIRT676918 KLHDC8A kelch domain containing 8A 2 2
MIRT676944 S1PR3 sphingosine-1-phosphate receptor 3 2 2
MIRT676957 HFE hemochromatosis 2 2
MIRT676967 RNF19B ring finger protein 19B 2 2
MIRT676972 ZNF708 zinc finger protein 708 2 2
MIRT677042 ZNF34 zinc finger protein 34 2 2
MIRT677070 VMAC vimentin type intermediate filament associated coiled-coil protein 2 2
MIRT677093 MFSD11 major facilitator superfamily domain containing 11 2 4
MIRT677134 P2RX7 purinergic receptor P2X 7 2 2
MIRT677179 ZNF786 zinc finger protein 786 2 2
MIRT677228 C15orf40 chromosome 15 open reading frame 40 2 2
MIRT677320 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 2
MIRT677455 PDLIM3 PDZ and LIM domain 3 2 2
MIRT677809 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT677937 ZNF519 zinc finger protein 519 2 2
MIRT678063 UBN2 ubinuclein 2 2 4
MIRT678072 EIF2A eukaryotic translation initiation factor 2A 2 2
MIRT678252 FXN frataxin 2 2
MIRT678315 FBLIM1 filamin binding LIM protein 1 2 2
MIRT678367 XIAP X-linked inhibitor of apoptosis 2 4
MIRT678372 RNF115 ring finger protein 115 2 2
MIRT678410 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678518 ZNF347 zinc finger protein 347 2 2
MIRT678566 CDK4 cyclin dependent kinase 4 2 2
MIRT678580 PPP1R3B protein phosphatase 1 regulatory subunit 3B 2 2
MIRT678820 PDE6A phosphodiesterase 6A 2 2
MIRT678917 XPOT exportin for tRNA 2 2
MIRT679217 MAN2A2 mannosidase alpha class 2A member 2 2 2
MIRT679437 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT679595 HILPDA hypoxia inducible lipid droplet associated 2 2
MIRT679755 TLR6 toll like receptor 6 2 2
MIRT679800 APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A 2 2
MIRT680057 CD96 CD96 molecule 2 2
MIRT680116 CCDC30 coiled-coil domain containing 30 2 4
MIRT680181 ZNF554 zinc finger protein 554 2 2
MIRT680439 WDR12 WD repeat domain 12 2 2
MIRT680789 ZNF578 zinc finger protein 578 2 2
MIRT692464 APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 2 2
MIRT702952 HIP1 huntingtin interacting protein 1 2 2
MIRT706016 ZSCAN2 zinc finger and SCAN domain containing 2 2 2
MIRT706032 F2R coagulation factor II thrombin receptor 2 2
MIRT706135 MTRNR2L10 MT-RNR2-like 10 2 2
MIRT706394 HAS2 hyaluronan synthase 2 2 2
MIRT713293 DCP2 decapping mRNA 2 2 2
MIRT716583 BRAP BRCA1 associated protein 2 2
MIRT720433 C19orf47 chromosome 19 open reading frame 47 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-640 Paclitaxel 36314 NSC125973 approved resistant High Ovarian Cancer tissue and cell line (SKOV3)
hsa-miR-640 Cetuximab resistant High Colon Cancer cell line
hsa-miR-640 Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (WM266) (1uM)
hsa-miR-640 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (WM266) (1uM)
hsa-miR-640 Mitoxantrone 4212 NSC279836 approved resistant High Breast Cancer cell line (BT-20, BT-474, BT-549, CAMA-1, HCC1143, HCC1395, HCC1569, HCC1806, HCC-1937, HCC1954, HCC202, HCC38, HCC70, Hs578T, MCF-7, MDA-MB-175VII, MDA-MB-231, MDA-MB-361, MDA-MB-415, MDA-MB-436, MDA-MB-468, SKBR3, T47D, UACC812, EVSA-T, MPE-600 , SK-BR-
hsa-miR-640 Sorafenib 216239 NSC747971 approved sensitive Low Clear Cell Renal Cell Carcinoma cell line (786-O)
hsa-mir-640 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-640 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-640 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-640 Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-640 Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-640 Tamoxifen 2733525 NSC180973 approved sensitive cell line (TamR8)
hsa-miR-640 Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-640 Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-640 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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