miRTarBase - #MIRT615201


—
pre-miRNA Information
pre-miRNA hsa-mir-6769b   
Genomic Coordinates chr1: 206474803 - 206474864
Description Homo sapiens miR-6769b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6769b-3p
Sequence 42| CCCUCUCUGUCCCACCCAUAG |62
Evidence Experimental
Experiments Meta-analysis
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN26671848 9 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs555627187 3 dbSNP
rs782102173 4 dbSNP
rs201952639 7 dbSNP
rs782001154 9 dbSNP
rs1488064450 15 dbSNP
rs782111367 16 dbSNP
rs370859899 18 dbSNP
rs1305197911 19 dbSNP
Putative Targets

Gene Information
Gene Symbol CLUAP1   
Synonyms CFAP22, FAP22, IFT38
Description clusterin associated protein 1
Transcript NM_015041   
Other Transcripts NM_024793   
Expression
Putative miRNA Targets on CLUAP1
3'UTR of CLUAP1
(miRNA target sites are highlighted)		 
>CLUAP1|NM_015041|3'UTR
   1 CCCTTTTGCCAAGGGACCCTGGCAGATTAAAACCCTCAGACTTGTAGGTAAATGGGAACTTAGAAGGTTAGGAAGGTAAC
  81 CCCTGTTTTGTTTACTAAGCTGGCTGGACTCATGATCACTGAAGCAATACTTATTTCTGCTTTAGCCTCCTATGTTTGCA
 161 TTCCATGAAGCTTAAATAAGAATTGAAGCAAATCCCTAAGATTTATTTTTTTCCACCTTATTTATCTTCTAAAACTTGAG
 241 GAATGCATGTGTTCTTAGTGATTCACATCCACGGGACAAAAACTCAAGAAGAAATAAGAGCTGACGCCACACAAGTCTTG
 321 GCTGCTTTTGTTACTATACATTTTCTCTGAGACTCCAGCAGAGTTGGGGCTGGAACTTGGCACTGGGGACTCATGTTTGG
 401 AATCGTAGGGGAACATCTGGCTGTTAATCACTTGCACAGTTGAGAACATTTCCTATACATCGGCTTTTAATTCTAGCTCT
 481 TATTTCATTTTGTAATCTTATTTTCTTTCGTCTGCATGTTCACAATACCAAGCATTAAATGTATTTTAATAACTAAACTT
 561 TTCTGAAAGAAGGTTAGCTAAAGTTAAATGAAAACTTGGTTTCTTTGAAAATCAGGCAATAGAGACAGGCTCCAGATGAG
 641 GAATCCTCCATTTTCTGTCCGAAGCTGACATTCCTCTGGCAGTCCAGTTCACCTTGGATTACAGCCACCTTCATGTTTCC
 721 ACGGTTGGTACTAAATCTGGAAACTCTGGTGACCTGGGCTGCCCTCTCAGAAACTCCAGACTCCCATGGCAATGACAGCC
 801 GGGACACTTTTCTTCCCTCCAGCCAGGGTTTCTCTAAAGGAGCTTTGTTTTGTCTAAAGTGTGGCAAGACATAGTGCACA
 881 ACACAGGGACAAAGGCAGGTTTCCTGCAGCTCGCTACCTAAGTGTTTCTGTAGGGGAAGGAGCCAATTAAGAAAAAGTGT
 961 TGGTACAGATTCATGTTTCTGATTTAAAAAAACAACAACACAGGATTGAATTAAGTAGAGTAATAGCACTAGAAGAATTT
1041 TTCTGTTGTGAAATTAGAAGTGGAGTTGGTTTTTTTCTTTTTTCTTCTTCTTTTTTTTTAATATGAAAAGTACTTAGCTG
1121 GGAGTGGTGGCAAGCGCCCTTGGGTCCAGCTACTCAGGAGGCCAAGGTGGGAGGATCACTTGAGCCCAGGAGTTTTAGAC
1201 TAGCCTGGACAACTAAGTGAGACTCCATCTCTACAAAAAATTAAAAAATTAGCCAGGTGTGGAGGGGCATGCCTGTGGTC
1281 TCAGCTATTCAGGAGGCTGAGGCAGGAGAATCACTTGAGACCAGGAAGTTGAGGCTGCAATGAGCCGTGATCATGCCACT
1361 GCACTCCAGCCTGGGTGACAGAGTGAGACCCTGTCTTTAAAAAAAAGAAAAAGAAAAGCACGCTGCTTGTAAAAAGCGTA
1441 CAGTAGGTCAGGCGTGGTGGCTCATGCCTGTAATCCTAGCACTTTGAGAGGCTGAGGTGGGTAGATCACCTGAGGTCAGG
1521 GGTTTGAGACCAGCCTGGCCAACATGGCGAAACCCCACCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTAGCGCAT
1601 GCCTGTAACCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTAGGAGGCGGAGGTTGCAGTGAGCCGAGA
1681 TGGCGCCACTGCACTCCAGCCTGGGCAGCAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAGCATACAGTAA
1761 ATAAAAAAGCACAAAACAGTTTTCACTTATTTTACAATTAAAAAGTCAGAAGACTTCTGAAGTTACTTATCTTTTAATAC
1841 ATGTATTTAACACCATACTTCATATTATTAAATAGGTTTTACTTAAAAATATAATTATTGTATTTGTACCTGTCAGATAT
1921 AAATACTTATTCAGGAGTTCACAGGTACGAAAAGATACACATAAATTTTAGGAACTTTTGAGTTATTTCTGTCATTTTTG
2001 CTTTTTTCTCTTTCTTTTCCTAAATTTTATGTATAAGATTACCCCTAAAAAAAAAAAAACAGCCAGTATTCAGTGAATTC
2081 ACCAGTAATTTGAAATGCACCATATTGTAAATGATCCACTGACAGGGAAGCCAGCGTGTTGGAGCCATGCCAGCCACCTC
2161 AGACACCGTGGCTCTAAGATGCGGAAGAGTCACTGCATCTTCTTGAATGTTACAGATTTGGTTTGCCTGAATGTGACTTG
2241 ACTTCTGTTTTGAAAAAACATACGAATAGAGTTCTATTTTCCTTATGTGATGCTTTCTTCTAACACACTTTAACACAGAA
2321 GCCTAACCTAGCTACAAAGAGCCTATCCACAGACATAGGCAACAGCTCCAAAGGGTATTTCATTGTGTCACCTGCTTCTA
2401 GATCATCTGTTAGTTAACTGACTTTGTGCAAGGTCTCACCATGTATAGCACTGCCTTGCTTGAGCACGGAAGTTTCTGTC
2481 AACAGCAAGCTTTATGTGCTCTATCATTTTTATTAAAGTATTTCAGTCAATAGTGACCCATTGTAGAATGGATGCAGGAT
2561 TCACATGTGCAAGTGCTTTGTGACCTGGCACCATTTGGTTTTGGCCAAGCAGCAGAGCAGACCTCAGGACCTAACGAGGA
2641 TGGTTGTGATTAGGTCAAATAGAAAACTAGCAGGCCATTGCTGACAATTTTTACTATATAATTAGAGGACTTCCTAAAAT
2721 GCTTTAAAAAAAAATGTGTATGGATGGAAAATACAAAGGAATTTTTCAAATACTCAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gauacccacccuguCUCUCCc 5'
                        |||||| 
Target 5' aatcctagcactttGAGAGGc 3'
 1472 - 1492 120.00 -7.90
2 
miRNA  3' gauACCCACCCUGUCUCUCcc 5'
             |||||  ||||||| |  
Target 5' gccTGGGT--GACAGAGTGag 3'
 1369 - 1387 118.00 -17.90
3 
miRNA  3' gauacccaCCCUGUCUCUCCc 5'
                  || :::|||:|| 
Target 5' attagccaGGTGTGGAGGGGc 3'
 1248 - 1268 117.00 -13.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20078710 9 COSMIC
COSN30448240 36 COSMIC
COSN19727390 37 COSMIC
COSN26971062 76 COSMIC
COSN23086682 84 COSMIC
COSN30184715 103 COSMIC
COSN31611759 116 COSMIC
COSN30153871 122 COSMIC
COSN31572825 146 COSMIC
COSN15658365 315 COSMIC
COSN24157713 481 COSMIC
COSN6084874 511 COSMIC
COSN5406831 649 COSMIC
COSN30379427 661 COSMIC
COSN5857286 724 COSMIC
COSN4765254 779 COSMIC
COSN8391443 781 COSMIC
COSN17182216 863 COSMIC
COSN26741591 952 COSMIC
COSN6084875 1312 COSMIC
COSN15597287 1436 COSMIC
COSN5800509 1534 COSMIC
COSN4765255 1689 COSMIC
COSN27198034 2060 COSMIC
COSN27431610 2060 COSMIC
COSN28012067 2061 COSMIC
COSN23509622 2137 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs145278481 3 dbSNP
rs776986723 9 dbSNP
rs1415827579 12 dbSNP
rs762474201 13 dbSNP
rs1207024572 14 dbSNP
rs770248966 16 dbSNP
rs745862135 17 dbSNP
rs773759602 18 dbSNP
rs759227390 20 dbSNP
rs767084888 21 dbSNP
rs752197699 24 dbSNP
rs370663489 25 dbSNP
rs201924645 31 dbSNP
rs757236414 39 dbSNP
rs376816338 49 dbSNP
rs758106510 50 dbSNP
rs1435215673 62 dbSNP
rs1357045850 63 dbSNP
rs1318172977 68 dbSNP
rs1399748355 74 dbSNP
rs960242098 77 dbSNP
rs1164206162 78 dbSNP
rs1473957899 79 dbSNP
rs143456139 84 dbSNP
rs34821558 84 dbSNP
rs1450212201 86 dbSNP
rs1249977232 89 dbSNP
rs759033910 91 dbSNP
rs1339750522 98 dbSNP
rs968285960 104 dbSNP
rs1197511786 105 dbSNP
rs978307460 125 dbSNP
rs978555916 126 dbSNP
rs921714431 131 dbSNP
rs924092018 135 dbSNP
rs1429341640 141 dbSNP
rs1331362319 145 dbSNP
rs953136720 149 dbSNP
rs1407487138 153 dbSNP
rs939463769 155 dbSNP
rs545387773 166 dbSNP
rs1364071300 169 dbSNP
rs1163590838 176 dbSNP
rs1430943904 178 dbSNP
rs992626662 183 dbSNP
rs1166236836 191 dbSNP
rs1186010482 197 dbSNP
rs1475101062 206 dbSNP
rs1368257213 211 dbSNP
rs1475923261 212 dbSNP
rs552382026 215 dbSNP
rs376553240 221 dbSNP
rs916581318 222 dbSNP
rs1489810101 227 dbSNP
rs564495457 230 dbSNP
rs1205854145 235 dbSNP
rs760750991 239 dbSNP
rs527313906 248 dbSNP
rs1213503852 249 dbSNP
rs940944360 267 dbSNP
rs898443655 268 dbSNP
rs1395029807 269 dbSNP
rs547056812 273 dbSNP
rs187831962 274 dbSNP
rs529783076 295 dbSNP
rs905304701 297 dbSNP
rs1007980212 299 dbSNP
rs1018004323 306 dbSNP
rs1311513786 307 dbSNP
rs1056885786 308 dbSNP
rs1479570748 310 dbSNP
rs1428785072 311 dbSNP
rs775643903 315 dbSNP
rs1182632679 324 dbSNP
rs1326822639 325 dbSNP
rs1483886942 332 dbSNP
rs1229399162 335 dbSNP
rs192595616 337 dbSNP
rs370990221 338 dbSNP
rs1021281507 340 dbSNP
rs1280114601 341 dbSNP
rs1281151510 341 dbSNP
rs1221096044 342 dbSNP
rs569788890 356 dbSNP
rs1322411565 357 dbSNP
rs968357572 360 dbSNP
rs1229417135 364 dbSNP
rs1486657892 365 dbSNP
rs1010116652 371 dbSNP
rs1198981119 372 dbSNP
rs113499009 384 dbSNP
rs767122770 393 dbSNP
rs1000007245 395 dbSNP
rs1405658020 396 dbSNP
rs184414370 396 dbSNP
rs1160154186 398 dbSNP
rs1031185847 400 dbSNP
rs961117921 405 dbSNP
rs992262235 406 dbSNP
rs74703634 407 dbSNP
rs548525071 409 dbSNP
rs1388691243 417 dbSNP
rs1239065837 432 dbSNP
rs1201266351 433 dbSNP
rs534199350 435 dbSNP
rs374296198 437 dbSNP
rs1268420538 439 dbSNP
rs987201220 441 dbSNP
rs1174742167 444 dbSNP
rs1319172002 456 dbSNP
rs969428936 460 dbSNP
rs1223517938 462 dbSNP
rs760337967 463 dbSNP
rs554242195 472 dbSNP
rs1450607268 478 dbSNP
rs974074649 478 dbSNP
rs919901104 481 dbSNP
rs1382089667 483 dbSNP
rs1385268544 498 dbSNP
rs1455529082 510 dbSNP
rs929930519 511 dbSNP
rs1158114999 519 dbSNP
rs574160433 531 dbSNP
rs1047383957 537 dbSNP
rs920871754 542 dbSNP
rs1181653929 557 dbSNP
rs1248098150 564 dbSNP
rs1190175362 569 dbSNP
rs1484696492 570 dbSNP
rs376418140 572 dbSNP
rs542795712 574 dbSNP
rs1215557757 575 dbSNP
rs556678540 578 dbSNP
rs751771364 582 dbSNP
rs1294639109 584 dbSNP
rs1244419092 585 dbSNP
rs762162822 589 dbSNP
rs899606669 590 dbSNP
rs1298445365 593 dbSNP
rs1383932317 594 dbSNP
rs1360177675 596 dbSNP
rs1234940235 618 dbSNP
rs193292964 620 dbSNP
rs1436988639 633 dbSNP
rs1042757821 645 dbSNP
rs1045271941 649 dbSNP
rs1423908073 661 dbSNP
rs576564547 662 dbSNP
rs545656950 664 dbSNP
rs1255460487 665 dbSNP
rs1351743348 674 dbSNP
rs145429006 681 dbSNP
rs1056516712 686 dbSNP
rs1191383393 688 dbSNP
rs1489050687 693 dbSNP
rs1271479051 696 dbSNP
rs866438862 697 dbSNP
rs1464696997 704 dbSNP
rs1359360209 705 dbSNP
rs867146316 708 dbSNP
rs1275928550 710 dbSNP
rs565254079 716 dbSNP
rs1194822507 723 dbSNP
rs1305819247 724 dbSNP
rs1295171952 735 dbSNP
rs1255493664 741 dbSNP
rs1431911578 742 dbSNP
rs892536538 744 dbSNP
rs1404034624 753 dbSNP
rs371122237 759 dbSNP
rs1031634684 765 dbSNP
rs960978897 767 dbSNP
rs188712361 782 dbSNP
rs1371997754 787 dbSNP
rs1455039402 790 dbSNP
rs1023747170 793 dbSNP
rs1176411771 794 dbSNP
rs73503381 799 dbSNP
rs1366941866 801 dbSNP
rs1490275501 802 dbSNP
rs560593619 804 dbSNP
rs142644469 806 dbSNP
rs1327644626 817 dbSNP
rs146916040 825 dbSNP
rs1009140746 828 dbSNP
rs1018738414 829 dbSNP
rs1222693123 835 dbSNP
rs961773688 844 dbSNP
rs1317524484 846 dbSNP
rs1241484701 848 dbSNP
rs951425615 857 dbSNP
rs1328721845 859 dbSNP
rs971753093 862 dbSNP
rs982796013 865 dbSNP
rs569783872 867 dbSNP
rs1487823809 870 dbSNP
rs1480339075 878 dbSNP
rs981007656 891 dbSNP
rs192551576 905 dbSNP
rs568366408 910 dbSNP
rs939568316 913 dbSNP
rs1039586058 914 dbSNP
rs992733353 915 dbSNP
rs1462669890 919 dbSNP
rs1261553757 931 dbSNP
rs1203269188 940 dbSNP
rs1329682553 947 dbSNP
rs1262283579 952 dbSNP
rs1236530619 953 dbSNP
rs1335136090 955 dbSNP
rs1313286252 956 dbSNP
rs1454165444 958 dbSNP
rs1250622847 961 dbSNP
rs1457428114 963 dbSNP
rs914009194 965 dbSNP
rs1160656565 972 dbSNP
rs1452027281 976 dbSNP
rs1363750261 983 dbSNP
rs562521439 986 dbSNP
rs921069425 986 dbSNP
rs1228630608 991 dbSNP
rs947139149 991 dbSNP
rs1043718142 996 dbSNP
rs1410833490 997 dbSNP
rs1461611978 1000 dbSNP
rs1349660443 1001 dbSNP
rs1042786337 1002 dbSNP
rs1266006579 1005 dbSNP
rs565964157 1007 dbSNP
rs536524852 1014 dbSNP
rs1248080448 1019 dbSNP
rs902854468 1021 dbSNP
rs534944442 1030 dbSNP
rs1313750850 1031 dbSNP
rs1435101673 1034 dbSNP
rs1056796240 1038 dbSNP
rs143243334 1041 dbSNP
rs757055627 1052 dbSNP
rs1315729149 1054 dbSNP
rs74906935 1056 dbSNP
rs905332320 1062 dbSNP
rs995557523 1070 dbSNP
rs1164843610 1071 dbSNP
rs536705600 1071 dbSNP
rs1050401619 1078 dbSNP
rs1298639582 1082 dbSNP
rs1383858317 1082 dbSNP
rs1374176137 1085 dbSNP
rs1393260377 1088 dbSNP
rs556405465 1089 dbSNP
rs1286494991 1090 dbSNP
rs1008757175 1091 dbSNP
rs1244108764 1091 dbSNP
rs576548250 1091 dbSNP
rs889030549 1091 dbSNP
rs1446281713 1094 dbSNP
rs1019182054 1100 dbSNP
rs1027518505 1100 dbSNP
rs1350170767 1101 dbSNP
rs1234113311 1102 dbSNP
rs1489839481 1103 dbSNP
rs1295517504 1104 dbSNP
rs1320225039 1105 dbSNP
rs538834071 1108 dbSNP
rs558756675 1123 dbSNP
rs897592137 1124 dbSNP
rs1340832786 1131 dbSNP
rs993223129 1132 dbSNP
rs1226233080 1136 dbSNP
rs1027325477 1137 dbSNP
rs951658747 1138 dbSNP
rs1407107668 1142 dbSNP
rs1364276824 1153 dbSNP
rs1303055551 1168 dbSNP
rs1252359145 1188 dbSNP
rs1410645567 1193 dbSNP
rs983213393 1193 dbSNP
rs1019597107 1205 dbSNP
rs980836443 1207 dbSNP
rs1481893938 1208 dbSNP
rs1202461527 1226 dbSNP
rs1213943954 1235 dbSNP
rs1201352824 1237 dbSNP
rs150425402 1244 dbSNP
rs975303846 1245 dbSNP
rs961226986 1251 dbSNP
rs1475365431 1253 dbSNP
rs138228342 1258 dbSNP
rs1411395756 1268 dbSNP
rs1270290851 1272 dbSNP
rs1194670746 1279 dbSNP
rs1323853660 1283 dbSNP
rs1422977442 1296 dbSNP
rs947167146 1299 dbSNP
rs978607501 1302 dbSNP
rs945479401 1304 dbSNP
rs1274851071 1309 dbSNP
rs979453712 1316 dbSNP
rs1170853988 1322 dbSNP
rs113520372 1328 dbSNP
rs1409408978 1334 dbSNP
rs1407138944 1336 dbSNP
rs925364774 1337 dbSNP
rs934407858 1338 dbSNP
rs8052563 1341 dbSNP
rs895462066 1347 dbSNP
rs1050174804 1353 dbSNP
rs1471122763 1357 dbSNP
rs1231063440 1358 dbSNP
rs1446858209 1363 dbSNP
rs1461360859 1365 dbSNP
rs1264665464 1367 dbSNP
rs1369961607 1373 dbSNP
rs543475457 1375 dbSNP
rs1415634458 1377 dbSNP
rs1295311649 1378 dbSNP
rs1377467104 1379 dbSNP
rs1228163639 1380 dbSNP
rs1278381063 1382 dbSNP
rs563252786 1390 dbSNP
rs771977973 1391 dbSNP
rs1278240328 1392 dbSNP
rs1309854693 1393 dbSNP
rs1226821695 1394 dbSNP
rs1446191771 1398 dbSNP
rs1339017285 1399 dbSNP
rs1468419113 1399 dbSNP
rs532268086 1399 dbSNP
rs1405548008 1402 dbSNP
rs1485689036 1404 dbSNP
rs1402182889 1407 dbSNP
rs552378597 1408 dbSNP
rs1157900944 1409 dbSNP
rs1444789424 1422 dbSNP
rs1244435298 1423 dbSNP
rs944593326 1424 dbSNP
rs573828101 1425 dbSNP
rs559633777 1430 dbSNP
rs1482704150 1435 dbSNP
rs1027137671 1438 dbSNP
rs887219094 1439 dbSNP
rs897623373 1442 dbSNP
rs1360332136 1444 dbSNP
rs993254052 1446 dbSNP
rs1167814480 1447 dbSNP
rs1378748046 1448 dbSNP
rs1004270636 1450 dbSNP
rs1389667698 1454 dbSNP
rs1343213676 1455 dbSNP
rs528354211 1461 dbSNP
rs1425242975 1465 dbSNP
rs1336226675 1467 dbSNP
rs548508139 1468 dbSNP
rs750373503 1469 dbSNP
rs1447569375 1493 dbSNP
rs965332674 1501 dbSNP
rs1443424622 1505 dbSNP
rs777723139 1506 dbSNP
rs975333294 1510 dbSNP
rs1028275728 1515 dbSNP
rs34107792 1518 dbSNP
rs1487092337 1523 dbSNP
rs1240704742 1528 dbSNP
rs1216271165 1535 dbSNP
rs1490657415 1539 dbSNP
rs746877518 1545 dbSNP
rs184904335 1550 dbSNP
rs1296646970 1559 dbSNP
rs979024227 1560 dbSNP
rs1360065337 1562 dbSNP
rs1297364516 1583 dbSNP
rs1297449963 1585 dbSNP
rs1349203205 1586 dbSNP
rs536267802 1590 dbSNP
rs1235901285 1597 dbSNP
rs1021079836 1598 dbSNP
rs924441812 1602 dbSNP
rs1215989849 1604 dbSNP
rs550184985 1610 dbSNP
rs1193421718 1620 dbSNP
rs189789035 1620 dbSNP
rs1480955967 1637 dbSNP
rs1271733700 1639 dbSNP
rs925396538 1643 dbSNP
rs1488232164 1644 dbSNP
rs1206635754 1646 dbSNP
rs1306018317 1647 dbSNP
rs1463347640 1648 dbSNP
rs1277745337 1653 dbSNP
rs1223938176 1654 dbSNP
rs1187879066 1660 dbSNP
rs59650409 1661 dbSNP
rs985492051 1665 dbSNP
rs1397050724 1666 dbSNP
rs1455508253 1677 dbSNP
rs1459990137 1685 dbSNP
rs1399157194 1686 dbSNP
rs912531124 1689 dbSNP
rs1470547208 1690 dbSNP
rs1174462656 1691 dbSNP
rs1423141946 1692 dbSNP
rs1414137230 1694 dbSNP
rs1160049512 1699 dbSNP
rs558713699 1712 dbSNP
rs1391314200 1714 dbSNP
rs1179046549 1717 dbSNP
rs1479683890 1721 dbSNP
rs1433408149 1727 dbSNP
rs1244384433 1728 dbSNP
rs1309030574 1728 dbSNP
rs1336309297 1728 dbSNP
rs1337052823 1728 dbSNP
rs1375516604 1728 dbSNP
rs1389219738 1728 dbSNP
rs34360832 1728 dbSNP
rs527631148 1728 dbSNP
rs769197760 1728 dbSNP
rs1454261790 1735 dbSNP
rs1403365453 1736 dbSNP
rs1320266227 1737 dbSNP
rs1171226649 1738 dbSNP
rs1372445800 1739 dbSNP
rs1465816671 1739 dbSNP
rs1161870362 1742 dbSNP
rs1364924280 1742 dbSNP
rs1437976406 1750 dbSNP
rs1476041858 1751 dbSNP
rs1272585730 1752 dbSNP
rs1366204971 1754 dbSNP
rs12596887 1755 dbSNP
rs1224026063 1756 dbSNP
rs568352312 1758 dbSNP
rs1326616260 1759 dbSNP
rs1207923308 1763 dbSNP
rs1254290479 1763 dbSNP
rs572313136 1764 dbSNP
rs1469816320 1770 dbSNP
rs1196591495 1771 dbSNP
rs1245062345 1773 dbSNP
rs146038717 1775 dbSNP
rs1236778941 1790 dbSNP
rs12596890 1798 dbSNP
rs1315149955 1800 dbSNP
rs1454084562 1804 dbSNP
rs919167502 1810 dbSNP
rs1333065883 1812 dbSNP
rs1395845837 1814 dbSNP
rs1414511742 1825 dbSNP
rs1386124646 1827 dbSNP
rs1291201960 1832 dbSNP
rs776480886 1836 dbSNP
rs1044037684 1840 dbSNP
rs905477701 1842 dbSNP
rs1446469786 1845 dbSNP
rs1366981695 1850 dbSNP
rs1048906503 1853 dbSNP
rs887562663 1855 dbSNP
rs931553589 1862 dbSNP
rs1263602865 1863 dbSNP
rs574339422 1867 dbSNP
rs1054815048 1872 dbSNP
rs1292352165 1875 dbSNP
rs1247602971 1880 dbSNP
rs75684939 1896 dbSNP
rs60140661 1901 dbSNP
rs180816815 1903 dbSNP
rs1327769930 1912 dbSNP
rs1298189738 1913 dbSNP
rs1348819233 1915 dbSNP
rs1398498696 1919 dbSNP
rs1360473882 1926 dbSNP
rs545923845 1927 dbSNP
rs1442366607 1930 dbSNP
rs537866202 1931 dbSNP
rs1426699723 1946 dbSNP
rs901248178 1949 dbSNP
rs183753111 1950 dbSNP
rs1028308264 1955 dbSNP
rs189240799 1959 dbSNP
rs554519725 1962 dbSNP
rs561820165 1971 dbSNP
rs1477362534 1973 dbSNP
rs1000095902 1976 dbSNP
rs912573783 1981 dbSNP
rs965793007 1993 dbSNP
rs1449429780 1997 dbSNP
rs1195805189 1998 dbSNP
rs1289117286 2001 dbSNP
rs1438289054 2002 dbSNP
rs1341079035 2005 dbSNP
rs1217238607 2009 dbSNP
rs972725520 2009 dbSNP
rs1205389182 2011 dbSNP
rs1340293355 2013 dbSNP
rs919198651 2015 dbSNP
rs1407311241 2021 dbSNP
rs1329786216 2028 dbSNP
rs1323004869 2033 dbSNP
rs781452756 2034 dbSNP
rs1410552949 2043 dbSNP
rs1254052211 2046 dbSNP
rs1398965778 2047 dbSNP
rs1450636301 2047 dbSNP
rs570322073 2047 dbSNP
rs530864577 2048 dbSNP
rs1181933813 2054 dbSNP
rs1439021050 2056 dbSNP
rs1255805266 2057 dbSNP
rs1165993702 2060 dbSNP
rs59258212 2060 dbSNP
rs1393447574 2061 dbSNP
rs1048936894 2063 dbSNP
rs1323727007 2065 dbSNP
rs955867746 2066 dbSNP
rs1473952150 2069 dbSNP
rs1221251992 2077 dbSNP
rs909013802 2086 dbSNP
rs1274750676 2092 dbSNP
rs748500165 2098 dbSNP
rs937776263 2099 dbSNP
rs993063298 2103 dbSNP
rs1161804403 2106 dbSNP
rs917035801 2120 dbSNP
rs549907298 2121 dbSNP
rs1412495660 2122 dbSNP
rs1390694414 2127 dbSNP
rs1159044893 2128 dbSNP
rs969761741 2136 dbSNP
rs570076526 2137 dbSNP
rs949081478 2138 dbSNP
rs1368102790 2148 dbSNP
rs1042026050 2152 dbSNP
rs920231951 2154 dbSNP
rs931574479 2165 dbSNP
rs1224817892 2166 dbSNP
rs115308832 2168 dbSNP
rs908711436 2169 dbSNP
rs940234385 2170 dbSNP
rs539660679 2176 dbSNP
rs1304788077 2181 dbSNP
rs1283373608 2183 dbSNP
rs1445595919 2183 dbSNP
rs552253588 2184 dbSNP
rs1230446268 2187 dbSNP
rs1318658037 2190 dbSNP
rs996919554 2193 dbSNP
rs1276869270 2206 dbSNP
rs1157549289 2212 dbSNP
rs1049777395 2215 dbSNP
rs965472901 2217 dbSNP
rs1179746737 2230 dbSNP
rs904487086 2233 dbSNP
rs556309814 2239 dbSNP
rs1025620149 2248 dbSNP
rs1031624159 2255 dbSNP
rs565905252 2258 dbSNP
rs1489576139 2261 dbSNP
rs181953331 2264 dbSNP
rs74779991 2265 dbSNP
rs1226834691 2269 dbSNP
rs1024081075 2270 dbSNP
rs369858816 2274 dbSNP
rs917690191 2277 dbSNP
rs754509353 2283 dbSNP
rs372838087 2284 dbSNP
rs1476037747 2291 dbSNP
rs568637601 2292 dbSNP
rs537794819 2297 dbSNP
rs936934307 2300 dbSNP
rs1351098250 2301 dbSNP
rs1054480881 2306 dbSNP
rs142173701 2307 dbSNP
rs1173678797 2309 dbSNP
rs758128501 2323 dbSNP
rs576911597 2329 dbSNP
rs1019767432 2334 dbSNP
rs1261706846 2344 dbSNP
rs140530883 2354 dbSNP
rs1193572530 2355 dbSNP
rs940247712 2368 dbSNP
rs1267307571 2369 dbSNP
rs1219413249 2375 dbSNP
rs1321372694 2376 dbSNP
rs1273946313 2377 dbSNP
rs1041261852 2390 dbSNP
rs1333278255 2404 dbSNP
rs1326735739 2412 dbSNP
rs1220279415 2426 dbSNP
rs1338138515 2431 dbSNP
rs1203350553 2442 dbSNP
rs1405501371 2446 dbSNP
rs1437226282 2463 dbSNP
rs535738918 2468 dbSNP
rs932726864 2469 dbSNP
rs1354803584 2472 dbSNP
rs1172337285 2478 dbSNP
rs1049808452 2479 dbSNP
rs1421920290 2479 dbSNP
rs1193312575 2480 dbSNP
rs1481068156 2481 dbSNP
rs1270033123 2486 dbSNP
rs746777658 2487 dbSNP
rs1488178819 2494 dbSNP
rs554597332 2496 dbSNP
rs757157447 2497 dbSNP
rs553120338 2498 dbSNP
rs573010775 2502 dbSNP
rs1233730315 2526 dbSNP
rs1053513275 2531 dbSNP
rs1347474346 2532 dbSNP
rs1257199123 2533 dbSNP
rs984112408 2540 dbSNP
rs1313905458 2541 dbSNP
rs891742593 2544 dbSNP
rs1014099109 2550 dbSNP
rs1198890963 2568 dbSNP
rs1255913291 2570 dbSNP
rs1465600468 2571 dbSNP
rs1333020214 2581 dbSNP
rs959307146 2587 dbSNP
rs1399042064 2591 dbSNP
rs1246767759 2593 dbSNP
rs1466852639 2594 dbSNP
rs1462778887 2596 dbSNP
rs61535266 2606 dbSNP
rs781184020 2609 dbSNP
rs1173779065 2611 dbSNP
rs1432731360 2616 dbSNP
rs917736837 2621 dbSNP
rs1180509995 2628 dbSNP
rs557209759 2630 dbSNP
rs771714159 2636 dbSNP
rs1237748089 2637 dbSNP
rs1378800736 2641 dbSNP
rs1001245472 2645 dbSNP
rs1204119095 2657 dbSNP
rs1484095142 2661 dbSNP
rs745849388 2662 dbSNP
rs949141923 2664 dbSNP
rs1317385318 2667 dbSNP
rs977777834 2668 dbSNP
rs1237262296 2675 dbSNP
rs923686418 2676 dbSNP
rs577165067 2677 dbSNP
rs936381670 2682 dbSNP
rs1053436896 2695 dbSNP
rs150737134 2698 dbSNP
rs1301397146 2699 dbSNP
rs951884499 2700 dbSNP
rs1465980702 2702 dbSNP
rs1381434197 2704 dbSNP
rs983160916 2706 dbSNP
rs1385429235 2711 dbSNP
rs377270930 2711 dbSNP
rs1437886212 2715 dbSNP
rs1041626012 2720 dbSNP
rs549886685 2726 dbSNP
rs901300508 2726 dbSNP
rs961662099 2726 dbSNP
rs1199598147 2727 dbSNP
rs774295870 2736 dbSNP
rs775102531 2740 dbSNP
rs922774720 2741 dbSNP
rs1213875315 2745 dbSNP
rs1318262409 2751 dbSNP
rs67733706 2754 dbSNP
rs763905466 2754 dbSNP
rs1246549880 2762 dbSNP
rs1005996190 2771 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084066. RNA binding protein: AGO2. Condition:CLIP_noemetine_SantaCruzAb HITS-CLIP data was present in GSM1084067. RNA binding protein: AGO2. Condition:CLIP_emetine_SantaCruzAb HITS-CLIP data was present in GSM1084068. RNA binding protein: AGO2. Condition:CLIP_noemetine_SigmaAb HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084081. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SantaCruzAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000576634.1 | 3UTR | GAAAAGGGAGAGAGGGAGGACUCUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084066
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SantaCruzAb
Location of target site ENST00000576634.1 | 3UTR | GAGAGAGGGAGGACUCUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084067
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_SantaCruzAb
Location of target site ENST00000576634.1 | 3UTR | AAAAGGGAGAGAGGGAGGACUCUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1084068
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SigmaAb
Location of target site ENST00000576634.1 | 3UTR | AGGGAGAGAGGGAGGACUCUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000576634.1 | 3UTR | AAAGGGAGAGAGGGAGGACUCUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084081
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_SantaCruzAb
Location of target site ENST00000576634.1 | 3UTR | AAAAGGGAGAGAGGGAGGACUCUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
209 hsa-miR-6769b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT181753 UHMK1 U2AF homology motif kinase 1 2 2
MIRT287119 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT395372 CDC42EP4 CDC42 effector protein 4 2 4
MIRT472533 NACC1 nucleus accumbens associated 1 2 4
MIRT472611 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT482405 ADRB1 adrenoceptor beta 1 2 10
MIRT492330 SETD1B SET domain containing 1B 2 2
MIRT499238 VAV3 vav guanine nucleotide exchange factor 3 2 6
MIRT512274 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT534548 RUNX1 runt related transcription factor 1 2 2
MIRT535374 PEX5L peroxisomal biogenesis factor 5 like 2 2
MIRT535424 PDZD8 PDZ domain containing 8 2 2
MIRT539329 AHSA2 activator of HSP90 ATPase homolog 2 2 4
MIRT569350 EFHC1 EF-hand domain containing 1 2 2
MIRT576116 Klf6 Kruppel-like factor 6 2 2
MIRT607241 LINS lines homolog 1 2 4
MIRT607364 ASAH2 N-acylsphingosine amidohydrolase 2 2 4
MIRT609572 CATSPER4 cation channel sperm associated 4 2 2
MIRT610045 SERPINA3 serpin family A member 3 2 2
MIRT610284 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 2 2
MIRT610302 KLHL21 kelch like family member 21 2 2
MIRT610393 FOXE1 forkhead box E1 2 2
MIRT610432 ASAH2B N-acylsphingosine amidohydrolase 2B 2 2
MIRT610510 BARHL2 BarH like homeobox 2 2 2
MIRT611818 FCRL4 Fc receptor like 4 2 2
MIRT612755 MYOCD myocardin 2 2
MIRT613698 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT613917 POU3F1 POU class 3 homeobox 1 2 2
MIRT615153 URGCP-MRPS24 URGCP-MRPS24 readthrough 2 2
MIRT615201 CLUAP1 clusterin associated protein 1 2 2
MIRT615338 ABCC12 ATP binding cassette subfamily C member 12 2 2
MIRT616706 UBXN2A UBX domain protein 2A 2 2
MIRT617186 GOSR2 golgi SNAP receptor complex member 2 2 4
MIRT617526 SORCS2 sortilin related VPS10 domain containing receptor 2 2 2
MIRT617596 NUDT5 nudix hydrolase 5 2 4
MIRT617763 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT618613 SHOX short stature homeobox 2 2
MIRT619301 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT619515 TXLNB taxilin beta 2 2
MIRT619925 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT619942 C8orf33 chromosome 8 open reading frame 33 2 2
MIRT620025 NFAM1 NFAT activating protein with ITAM motif 1 2 2
MIRT620554 C10orf10 chromosome 10 open reading frame 10 2 4
MIRT620752 CCR5 C-C motif chemokine receptor 5 (gene/pseudogene) 2 2
MIRT621798 TMEM233 transmembrane protein 233 2 2
MIRT621843 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT622693 PLSCR1 phospholipid scramblase 1 2 2
MIRT622733 PITPNM3 PITPNM family member 3 2 2
MIRT623004 ONECUT3 one cut homeobox 3 2 2
MIRT623211 MTFR1L mitochondrial fission regulator 1 like 2 2
MIRT623771 GPR37L1 G protein-coupled receptor 37 like 1 2 2
MIRT624119 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT624150 DIAPH1 diaphanous related formin 1 2 2
MIRT624443 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT624855 ABI2 abl interactor 2 2 2
MIRT625311 SHISA6 shisa family member 6 2 2
MIRT625741 MTSS1 MTSS1, I-BAR domain containing 2 2
MIRT626292 ZNF85 zinc finger protein 85 2 2
MIRT627400 TMEM170A transmembrane protein 170A 2 2
MIRT627464 SYNRG synergin gamma 2 2
MIRT627913 KANSL1 KAT8 regulatory NSL complex subunit 1 2 2
MIRT636508 GDAP1L1 ganglioside induced differentiation associated protein 1 like 1 2 2
MIRT636910 KIAA0408 KIAA0408 2 2
MIRT637302 ACTN2 actinin alpha 2 2 2
MIRT638230 SOGA3 SOGA family member 3 2 2
MIRT639880 STC1 stanniocalcin 1 2 2
MIRT639999 PHF21B PHD finger protein 21B 2 2
MIRT640149 CEP104 centrosomal protein 104 2 2
MIRT640699 SKI SKI proto-oncogene 2 2
MIRT640911 RAB13 RAB13, member RAS oncogene family 2 2
MIRT641518 CREBBP CREB binding protein 2 2
MIRT641990 OXSR1 oxidative stress responsive 1 2 2
MIRT642635 EPPIN epididymal peptidase inhibitor 2 2
MIRT642744 TDRD6 tudor domain containing 6 2 2
MIRT642759 SDHAF2 succinate dehydrogenase complex assembly factor 2 2 2
MIRT642787 CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 2 2
MIRT643054 EPPIN-WFDC6 EPPIN-WFDC6 readthrough 2 2
MIRT643104 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT643316 TMEM151B transmembrane protein 151B 2 2
MIRT643715 ITK IL2 inducible T-cell kinase 2 2
MIRT644087 A4GALT alpha 1,4-galactosyltransferase (P blood group) 2 2
MIRT644112 SEL1L3 SEL1L family member 3 2 2
MIRT644377 ZNF286A zinc finger protein 286A 2 2
MIRT644408 FRMD6 FERM domain containing 6 2 2
MIRT644684 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT644744 CCDC174 coiled-coil domain containing 174 2 2
MIRT644876 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT645417 FAM110A family with sequence similarity 110 member A 2 2
MIRT645928 PLXNA3 plexin A3 2 2
MIRT646181 PTPN14 protein tyrosine phosphatase, non-receptor type 14 2 2
MIRT646554 TMCC2 transmembrane and coiled-coil domain family 2 2 2
MIRT647235 OR6A2 olfactory receptor family 6 subfamily A member 2 2 2
MIRT647263 PTGDR2 prostaglandin D2 receptor 2 2 2
MIRT647660 FOXL1 forkhead box L1 2 2
MIRT648284 TRAPPC2L trafficking protein particle complex 2 like 2 2
MIRT648493 CMBL carboxymethylenebutenolidase homolog 2 2
MIRT648963 TMEM45B transmembrane protein 45B 2 2
MIRT649511 RAB17 RAB17, member RAS oncogene family 2 2
MIRT650446 CPXM2 carboxypeptidase X, M14 family member 2 2 2
MIRT650712 KRT32 keratin 32 2 2
MIRT651069 ZNF518B zinc finger protein 518B 2 4
MIRT651090 ZNF516 zinc finger protein 516 2 2
MIRT651193 ZNF281 zinc finger protein 281 2 2
MIRT651330 ZCCHC2 zinc finger CCHC-type containing 2 2 2
MIRT651445 XKR4 XK related 4 2 2
MIRT651517 WNT4 Wnt family member 4 2 4
MIRT651694 VPS13D vacuolar protein sorting 13 homolog D 2 2
MIRT652173 TRIM66 tripartite motif containing 66 2 2
MIRT652432 TMEM239 transmembrane protein 239 2 2
MIRT652656 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT652707 THBS2 thrombospondin 2 2 2
MIRT652812 TBL2 transducin beta like 2 2 2
MIRT653350 SMG7 SMG7, nonsense mediated mRNA decay factor 2 2
MIRT653471 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT653658 SLC27A4 solute carrier family 27 member 4 2 2
MIRT654691 PSMB5 proteasome subunit beta 5 2 2
MIRT654735 PRLR prolactin receptor 2 2
MIRT654931 POLR3D RNA polymerase III subunit D 2 2
MIRT655209 PHAX phosphorylated adaptor for RNA export 2 2
MIRT655346 PCP4L1 Purkinje cell protein 4 like 1 2 2
MIRT655404 PANK1 pantothenate kinase 1 2 2
MIRT655482 PAK3 p21 (RAC1) activated kinase 3 2 2
MIRT655964 NDNF neuron derived neurotrophic factor 2 2
MIRT656017 MYPN myopalladin 2 2
MIRT656491 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT657151 ITGA1 integrin subunit alpha 1 2 2
MIRT657411 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 2
MIRT657608 GRID1 glutamate ionotropic receptor delta type subunit 1 2 2
MIRT658181 FBXO9 F-box protein 9 2 2
MIRT658932 DPY19L1 dpy-19 like C-mannosyltransferase 1 2 2
MIRT659028 DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2 2
MIRT659092 DENR density regulated re-initiation and release factor 2 2
MIRT659204 CYBB cytochrome b-245 beta chain 2 2
MIRT659718 CCDC93 coiled-coil domain containing 93 2 2
MIRT660185 BNC2 basonuclin 2 2 2
MIRT660805 AIFM2 apoptosis inducing factor, mitochondria associated 2 2 2
MIRT660900 ADCY6 adenylate cyclase 6 2 2
MIRT660925 ADAM19 ADAM metallopeptidase domain 19 2 2
MIRT661741 DTHD1 death domain containing 1 2 2
MIRT661998 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT662639 PKHD1L1 PKHD1 like 1 2 2
MIRT664338 RAB8A RAB8A, member RAS oncogene family 2 2
MIRT666743 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT667070 PANK3 pantothenate kinase 3 2 2
MIRT667925 IGLON5 IgLON family member 5 2 2
MIRT668488 ETV3 ETS variant 3 2 2
MIRT668610 EHD4 EH domain containing 4 2 2
MIRT669419 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT669652 ACSBG1 acyl-CoA synthetase bubblegum family member 1 2 2
MIRT674005 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT680447 SLCO5A1 solute carrier organic anion transporter family member 5A1 2 2
MIRT684326 GTF3C4 general transcription factor IIIC subunit 4 2 2
MIRT685625 C12orf49 chromosome 12 open reading frame 49 2 2
MIRT689978 ZNF185 zinc finger protein 185 with LIM domain 2 2
MIRT693962 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT698543 TFRC transferrin receptor 2 2
MIRT699982 RREB1 ras responsive element binding protein 1 2 2
MIRT702898 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT707383 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT708312 CDH8 cadherin 8 2 2
MIRT708406 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT709299 LDLRAD4 low density lipoprotein receptor class A domain containing 4 2 2
MIRT710326 STK40 serine/threonine kinase 40 2 2
MIRT710729 C19orf68 zinc finger SWIM-type containing 9 2 2
MIRT710970 CMKLR1 chemerin chemokine-like receptor 1 2 2
MIRT711178 EMCN endomucin 2 2
MIRT711590 SETD1A SET domain containing 1A 2 2
MIRT711611 LHX5 LIM homeobox 5 2 2
MIRT711701 GMPR guanosine monophosphate reductase 2 2
MIRT711850 AMOTL2 angiomotin like 2 2 2
MIRT712358 NAT14 N-acetyltransferase 14 (putative) 2 2
MIRT712377 MTPN myotrophin 2 2
MIRT712469 KCNC3 potassium voltage-gated channel subfamily C member 3 2 2
MIRT712839 RHOA ras homolog family member A 2 2
MIRT713592 ANKMY1 ankyrin repeat and MYND domain containing 1 2 2
MIRT713982 ASIC4 acid sensing ion channel subunit family member 4 2 2
MIRT714534 ZBTB39 zinc finger and BTB domain containing 39 2 2
MIRT714570 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 2 2
MIRT714610 EXO5 exonuclease 5 2 2
MIRT714943 ZNF330 zinc finger protein 330 2 2
MIRT715132 ACADL acyl-CoA dehydrogenase, long chain 2 2
MIRT716018 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT716204 TYW3 tRNA-yW synthesizing protein 3 homolog 2 2
MIRT716674 PPP6R1 protein phosphatase 6 regulatory subunit 1 2 2
MIRT717366 EDN2 endothelin 2 2 2
MIRT718110 CRTC1 CREB regulated transcription coactivator 1 2 2
MIRT718502 GYS1 glycogen synthase 1 2 2
MIRT719146 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT719415 B4GALNT3 beta-1,4-N-acetyl-galactosaminyltransferase 3 2 2
MIRT719986 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT720347 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT720452 SLC16A5 solute carrier family 16 member 5 2 2
MIRT720493 TMEM178B transmembrane protein 178B 2 2
MIRT720666 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT721091 CCBE1 collagen and calcium binding EGF domains 1 2 2
MIRT721334 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT721384 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT721508 CARHSP1 calcium regulated heat stable protein 1 2 2
MIRT721827 POU6F1 POU class 6 homeobox 1 2 2
MIRT722136 TTLL11 tubulin tyrosine ligase like 11 2 2
MIRT723070 GGA1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 2 2
MIRT723115 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT723374 ZNF470 zinc finger protein 470 2 2
MIRT724446 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT724528 ATP2B1 ATPase plasma membrane Ca2+ transporting 1 2 2
MIRT724643 PKDREJ polycystin family receptor for egg jelly 2 2
MIRT724711 CRAMP1L cramped chromatin regulator homolog 1 2 2
MIRT724750 ZNF391 zinc finger protein 391 2 2
MIRT724770 PSG4 pregnancy specific beta-1-glycoprotein 4 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6769b Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-mir-6769b Docetaxel+Cisplatin+5-Fluorouracil sensitive tissue (hypopharyngeal squamous cell carcinoma)
hsa-miR-6769b-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-6769b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-6769b-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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