miRTarBase - #MIRT615677


—
pre-miRNA Information
pre-miRNA hsa-mir-2117   
Genomic Coordinates chr17: 43444806 - 43444885
Description Homo sapiens miR-2117 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-2117
Sequence 51| UGUUCUCUUUGCCAAGGACAG |71
Evidence Experimental
Experiments 454
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1255384593 12 dbSNP
rs1227862494 14 dbSNP
rs1458444919 16 dbSNP
rs1309101018 17 dbSNP
rs1159219853 18 dbSNP
rs1344029538 19 dbSNP
rs747666550 20 dbSNP
rs770495894 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol NAV2   
Synonyms HELAD1, POMFIL2, RAINB1, STEERIN2, UNC53H2
Description neuron navigator 2
Transcript NM_001111018   
Other Transcripts NM_001111019 , NM_145117 , NM_182964   
Expression
Putative miRNA Targets on NAV2
3'UTR of NAV2
(miRNA target sites are highlighted)		 
>NAV2|NM_001111018|3'UTR
   1 CAGGGGCCCGGAGCCCAGCGCCCTCCTCTTCTCCTCACCGCATTCCACCTGCATCCCCCACATCACCCTGAAGATGACTT
  81 CCTGAGCCAGCCCCCAGCCACAGCCTTAGAGCTGCGGGAACACCGAGACCCCCCGTCCTTCAGCCTCGACCTGGGTGCAG
 161 GCATCCCGGGCCAGCTGCCTGCGGACCGCTTCCTTCCACAGCGAGAACTGCACTACCTTCTGTTGTACTTTAATTATTGT
 241 TTTGCCTTGTTGCTGTGACCTCCCTAAGACACTGAAGATACTTCTCGGGAAAGGATCATCGCCGTTGAAATGAAAAGAGA
 321 GACAGAGAGAAAAAAAAAAAGAGAACCCACATGAAGCTCTGAAACCAAACAGCATCCTGCCATGAGCTTCCCAGAGACAG
 401 AAGAGACTGGAGCAAAGTCGGAAACACAGAGAAGCACGGCTTCCCCTCAGCACAGACCCTCCAGACTGGGTCTCAGAGCC
 481 GTGCCACCCACCCTCCCACACAGCCGGCCACAGGGAGAACTGGTGCTAACCAGGGTGCTTGCTTTGGTCACGTTCAACGC
 561 ACTACAGAGCTACGACACAGGGAAACCTTAGGAGCAAATAAACCGTGCTTTCATGTTTTTTAAATGGTGCTTTCCTTACC
 641 CGAGAGGTATTTTGCCTGTTCCAATCAAACCACCCCATTCAGGTCCATCAGCCTCTGATTAATATCCGTGAGAGTGAGTG
 721 ACGGAGTGAGAGTGTGAGCGAGTGGATGTGGCTGTCAGTGCAGAACAGCATGTGTCTCTTTCCTTCTGATATATGAATGA
 801 ATCAGGTTTTTTTTTTTTTTTTTCTGCAAACACTGTGTATAGTGAGACTTGTTCTACTTTGGAGAACAGGTTACCTTTTG
 881 AAAATGAGGTTGAGTTTCTTCCTTTCTGATGCATTGATTTTTGAAGATTTTTTTTTCCCCCTTCCCCTCTTGGTCAGAAT
 961 CAATCCTTTGGTGAAAGTAAGAACCGCAGGAGTTGAGTTTTGGTTTGGTCCTGCTCAGTTTTGGTTTTTAGTTGTCCATC
1041 CTCACAGTCCTACACACTCGCCTCCTCCTGCTAGGGCTGGGGGTATCTGTGTCCTTTAAAATGGATGAGGACCTGGTCCT
1121 CGACATGTGGGTGAGCCATGGACCTTGCCTTCCCTTCTCGTCCTTGAGGGTTTAGAACACACACCAACACCTCCAGCGTC
1201 CCCGCCCCAGCTTCCGGTGGGGTGATGCGGTCACCCTGCAAAAGACTTGCACTTTCCTCAGAACCAACATGACGCAGCTC
1281 AATAAGGGTGAGGGTCACTCCCTCCCAGAAGCCCCGTCTGGACGAGCCTTGCCTGACCTCTTCGGTGCTGACCTTCCCAA
1361 AGTGATGCCTTACTGGTTTTGTACTAACTGTGTTCATTTTACATAAGTGTCGTGCCTGCCTGGGGTTTGTTTTTTTTGTC
1441 ATTGTTTTCCCCATTGAAACAAACAGGGCTAAAAAGTCATCTGTTCATTAGGAGAACTCAAGTTGCTGTGACTTTTCTCA
1521 TCCAAAAGACTCATTTGTGTGGATGCGTGACCATGGGAAAAAGAAAAAAAAAAAGATCCATTTTTTAGGTTCTTTTCGGT
1601 CTCCAGCTGACAACCCAACTGGACAATGATCTGTCTGGTGCAGGAGAAGGCAAAAGTTTCTACAAGTCTACATGACCTTG
1681 CTGATACTTGTTCTAATAGAAACCCAGTCTGCTGTGTCTTCAACATACTGGTATTTTCATTACAAAGTATGGTAAATTTT
1761 TGAGTTGTTTGTTTCTGTTTTGTAAAGAGAATCCTTATTGGACACCAGTGAAGGTGTCTCTGTTTTAATGATCAGGGTTT
1841 TTATTCCATCTTTTGCATTTCTTCTATTTCTGAAGGTTTGTCTCTTGGCATCTTTTTTTAGTTTCTTACCATAAGAGTTT
1921 GACCCGAAACTGCTCACTTCACATTGGATGACACCATGTTCTTCCTCTTTGAAAAGAAAAGGGGAATGTGTCCCACTAGT
2001 GAAAGGAAAACTTTTCAACACTATCCCTGCTTTAGTCTCAGCAAACTCAGACTATTCTGCTTAGCCTTCATTAGTCATCT
2081 GGGTGTGAGTGTGTCTTGTTCTGTTTTTCTTTTTAATAAAACTTTTAAACCATATATTTAGCCTGTGACCAGGGGGGCCA
2161 AACCCTAAGATTTCTGGTAAACCTGAAGGGTGGCCCTCCTCAGACAATTTATCTCCCAGCAATGACCCTACTACACTCGC
2241 GTACTGTGAATTTGGGAGGAGGTAAAGTTGACTTCTCCTCGTGGGCAGTTTTCCAATCACCTTGTGAGTAGACACCTGCC
2321 AATATTGTTTGAAACCTTTTTTTAATATGACATCCTCTCTTGTCATTCTCTTCTCCCCTTTCCCACAGACTTCCCTCCTG
2401 GGTCCAGGTTCAGAACCAAGACTTCTGTACCTAGTGCTGCCTGATTGGTGAACATTGACTTCAAGTAGCATAGCCCTTGT
2481 GTGACTCACAACTCCGTGTCCTTCCTAAAGTTTCGGGAAGCAGGGTTGTCTAATATGCACATTTCTTATTTTGGTCATAT
2561 TTTTACTTTAGTGTCACTCACCTTTTACAAAGTGACTTTGTACTCATTTAGGGCTCTATCGGAAATGCTTCCATTTTGCC
2641 TTTTCTACAGTTAGGCCAATTTTGAAATATATAAATTCTATGCAACATTTATGTTGAGTTACCAATGGAAGCCAAAAGTT
2721 CTCTTCCCAAACTGCCAAGAATGATACAGGCCATAATTGAAATGGGAATACCTTTTAAGTTTCATTAGGGGTGGGGTGGG
2801 AGTGGGACAGGAACAAGACTTGCCTAGATCTTTGTTGTATCTTGGGGACTTTTACTTTGTTGTTTGATGCTTAAACTTCA
2881 AAATTCTCTGTATTCAAATTTGATTGTGGCGAATCTACTTCAAAAAGGAAAAATAATCCAACTTTGTGGATATTAAATGG
2961 AAGGTTTGCTGTTTTGATCTAGTTGTTTCCAGTGGAGCAGTTTTATGAAATATGTTCTATAAGATGTACATTTTTTCATT
3041 GTAACATAGAAATTGTAAATAATTGATTAAAGTGCTGCATTTTGATGAATTTTTTCTAGCCATTTTTAAAGAGAAAACTA
3121 GGAATTGAGTATTTTGTGTACGGTATGTTTCCATCCTCCCTCCCCTTCCTCCTCCCCTCCTCTCTCTCTCTTCCTACCTA
3201 TTTAATTTTCATTTGTCATGAGGTTTTTGGATTTGCCAATGATCTGCTGGACATCATGCCCCATGTCATAGAGAATAAAG
3281 CTGATGATTGTACCAGTCTTAAATTATTCATGATTCAATAAAATTGATGCTTATTTATTCAGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gacaggaaccgUUUCUCUUGu 5'
                     ||||||||| 
Target 5' gagaaaaaaaaAAAGAGAACc 3'
 327 - 347 150.00 -8.90
2 
miRNA  3' gacAGGAACCGUUUCUCUUGu 5'
             | :|| |:||||||||: 
Target 5' ttcTGTTTTGTAAAGAGAATc 3'
 1773 - 1793 150.00 -16.40
3 
miRNA  3' gacaGGAACCGUUUCUCUUGu 5'
              || || || ||||||: 
Target 5' tgccCCATGTCATAGAGAATa 3'
 3257 - 3277 145.00 -12.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26985939 7 COSMIC
COSN30719407 21 COSMIC
COSN31613886 28 COSMIC
COSN30485333 34 COSMIC
COSN13316785 40 COSMIC
COSN13316786 41 COSMIC
COSN31503047 56 COSMIC
COSN26985942 57 COSMIC
COSN30472519 110 COSMIC
COSN30472486 112 COSMIC
COSN30124635 116 COSMIC
COSN31538208 125 COSMIC
COSN30504440 126 COSMIC
COSN30524400 128 COSMIC
COSN31552743 128 COSMIC
COSN28798023 134 COSMIC
COSN20108033 136 COSMIC
COSN31498364 142 COSMIC
COSN31596322 182 COSMIC
COSN30524409 185 COSMIC
COSN1523323 234 COSMIC
COSN5902910 321 COSMIC
COSN20108034 331 COSMIC
COSN28201369 332 COSMIC
COSN27382322 341 COSMIC
COSN28867462 341 COSMIC
COSN5300917 382 COSMIC
COSN17214737 404 COSMIC
COSN27748508 486 COSMIC
COSN26576390 547 COSMIC
COSN195137 568 COSMIC
COSN28735236 584 COSMIC
COSN27699731 609 COSMIC
COSN31536124 617 COSMIC
COSN32063439 732 COSMIC
COSN28273344 805 COSMIC
COSN17841123 815 COSMIC
COSN20108040 823 COSMIC
COSN1130339 824 COSMIC
COSN29540471 825 COSMIC
COSN1130340 831 COSMIC
COSN23035138 937 COSMIC
COSN15662602 941 COSMIC
COSN31541255 1161 COSMIC
COSN1130341 1181 COSMIC
COSN216736 1199 COSMIC
COSN17183030 1274 COSMIC
COSN30539696 1289 COSMIC
COSN6997235 1324 COSMIC
COSN30166654 1348 COSMIC
COSN29199885 1408 COSMIC
COSN30590044 1438 COSMIC
COSN31556110 1438 COSMIC
COSN25533893 1444 COSMIC
COSN31545260 1548 COSMIC
COSN1130342 1575 COSMIC
COSN28189434 1705 COSMIC
COSN30684147 1999 COSMIC
COSN1130343 2024 COSMIC
COSN26772593 2158 COSMIC
COSN2474127 2202 COSMIC
COSN31550926 2217 COSMIC
COSN31545687 2279 COSMIC
COSN30580840 2361 COSMIC
COSN20108044 2400 COSMIC
COSN24779247 2458 COSMIC
COSN20108045 2579 COSMIC
COSN31564677 2622 COSMIC
COSN24304013 2713 COSMIC
COSN19113294 2781 COSMIC
COSN22717277 2889 COSMIC
COSN31529627 2912 COSMIC
COSN31486053 3010 COSMIC
COSN26678042 3042 COSMIC
COSN28201351 3321 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1355527740 5 dbSNP
rs371029759 6 dbSNP
rs575118262 7 dbSNP
rs190558797 10 dbSNP
rs201569868 11 dbSNP
rs1169519526 14 dbSNP
rs960531991 18 dbSNP
rs992366157 20 dbSNP
rs201042317 21 dbSNP
rs1245242172 22 dbSNP
rs776049474 22 dbSNP
rs760922819 26 dbSNP
rs765380099 26 dbSNP
rs768722671 27 dbSNP
rs1317755704 29 dbSNP
rs1259120471 31 dbSNP
rs371342170 40 dbSNP
rs761742021 41 dbSNP
rs751484035 43 dbSNP
rs776178354 57 dbSNP
rs1266403501 58 dbSNP
rs1283036418 60 dbSNP
rs1448176985 67 dbSNP
rs1384541044 87 dbSNP
rs1490282394 88 dbSNP
rs1200657353 92 dbSNP
rs181514452 95 dbSNP
rs925970251 103 dbSNP
rs1445599380 115 dbSNP
rs935957543 116 dbSNP
rs78757042 117 dbSNP
rs913454394 122 dbSNP
rs1403489871 125 dbSNP
rs1007567541 126 dbSNP
rs1162706472 127 dbSNP
rs1019839494 128 dbSNP
rs1176935558 129 dbSNP
rs901339061 129 dbSNP
rs999613095 130 dbSNP
rs934224142 133 dbSNP
rs3802803 134 dbSNP
rs141058022 135 dbSNP
rs778716534 135 dbSNP
rs771502492 136 dbSNP
rs544433495 138 dbSNP
rs1238924370 148 dbSNP
rs1038095110 149 dbSNP
rs1369565624 153 dbSNP
rs1423528283 154 dbSNP
rs1299649214 156 dbSNP
rs1380461068 159 dbSNP
rs1294855035 160 dbSNP
rs969387184 162 dbSNP
rs980430526 168 dbSNP
rs898186755 169 dbSNP
rs560919771 183 dbSNP
rs113913642 184 dbSNP
rs1367452058 186 dbSNP
rs1025523303 188 dbSNP
rs746706744 189 dbSNP
rs1409049518 192 dbSNP
rs768294237 200 dbSNP
rs972558797 203 dbSNP
rs140305943 204 dbSNP
rs560449738 211 dbSNP
rs1490992866 213 dbSNP
rs1283203334 216 dbSNP
rs186998228 217 dbSNP
rs1223624814 219 dbSNP
rs980604245 222 dbSNP
rs1485134207 229 dbSNP
rs1033069116 233 dbSNP
rs754241487 243 dbSNP
rs1186429130 244 dbSNP
rs1217250559 246 dbSNP
rs369042431 249 dbSNP
rs1366571257 250 dbSNP
rs957358718 260 dbSNP
rs1406649043 286 dbSNP
rs988847424 287 dbSNP
rs1181858106 288 dbSNP
rs1384791127 290 dbSNP
rs913235491 293 dbSNP
rs942339765 298 dbSNP
rs1165134467 301 dbSNP
rs552577401 302 dbSNP
rs1451433051 304 dbSNP
rs2436186 305 dbSNP
rs757920603 312 dbSNP
rs911394214 313 dbSNP
rs942859303 320 dbSNP
rs531825069 322 dbSNP
rs1192291436 324 dbSNP
rs202116788 324 dbSNP
rs1261983923 328 dbSNP
rs1436600403 328 dbSNP
rs1485940383 328 dbSNP
rs1263474743 330 dbSNP
rs1312570797 330 dbSNP
rs764042925 330 dbSNP
rs1038089091 331 dbSNP
rs3839942 331 dbSNP
rs77011659 332 dbSNP
rs898217895 333 dbSNP
rs1290742788 340 dbSNP
rs929718860 368 dbSNP
rs1358857679 371 dbSNP
rs1312311337 380 dbSNP
rs766439207 397 dbSNP
rs901414130 401 dbSNP
rs1381514489 406 dbSNP
rs999685384 410 dbSNP
rs1228542320 411 dbSNP
rs546933264 413 dbSNP
rs1052534061 420 dbSNP
rs1046753812 421 dbSNP
rs766050283 423 dbSNP
rs1179629783 426 dbSNP
rs893920274 434 dbSNP
rs1243416819 435 dbSNP
rs1205318015 436 dbSNP
rs896138077 438 dbSNP
rs548791488 439 dbSNP
rs1315479504 448 dbSNP
rs1297791455 456 dbSNP
rs568556908 470 dbSNP
rs1382307808 478 dbSNP
rs1337705084 482 dbSNP
rs1269270451 488 dbSNP
rs777039310 490 dbSNP
rs1023522006 491 dbSNP
rs1398469391 494 dbSNP
rs1201789290 503 dbSNP
rs1242612862 506 dbSNP
rs905041627 507 dbSNP
rs1000664174 519 dbSNP
rs1032171624 526 dbSNP
rs751048262 536 dbSNP
rs1422798622 546 dbSNP
rs11025395 552 dbSNP
rs1184981616 553 dbSNP
rs1036056140 559 dbSNP
rs765596545 560 dbSNP
rs1196213213 562 dbSNP
rs773613256 565 dbSNP
rs1263683716 566 dbSNP
rs114447066 573 dbSNP
rs1358743577 576 dbSNP
rs3087788 584 dbSNP
rs911439134 587 dbSNP
rs918437908 588 dbSNP
rs964568668 595 dbSNP
rs1334045362 597 dbSNP
rs1404701271 600 dbSNP
rs974245682 605 dbSNP
rs1448181817 606 dbSNP
rs952502597 608 dbSNP
rs984278914 609 dbSNP
rs910939072 616 dbSNP
rs1164958149 622 dbSNP
rs150950128 642 dbSNP
rs920089872 643 dbSNP
rs1182256535 659 dbSNP
rs191786287 662 dbSNP
rs1420718275 665 dbSNP
rs766407138 667 dbSNP
rs894445 668 dbSNP
rs140710106 670 dbSNP
rs1292524477 674 dbSNP
rs1224881653 676 dbSNP
rs1351744326 677 dbSNP
rs1260428611 681 dbSNP
rs1240190232 682 dbSNP
rs1337836904 684 dbSNP
rs922867714 688 dbSNP
rs935572401 690 dbSNP
rs755306476 694 dbSNP
rs917585208 702 dbSNP
rs1223526651 705 dbSNP
rs949055136 708 dbSNP
rs184226098 709 dbSNP
rs187564710 711 dbSNP
rs1222216857 713 dbSNP
rs1158727359 717 dbSNP
rs1455024774 719 dbSNP
rs1263127204 723 dbSNP
rs1198442363 724 dbSNP
rs1480709522 726 dbSNP
rs1443053018 727 dbSNP
rs1212386042 728 dbSNP
rs540377373 735 dbSNP
rs1001189573 738 dbSNP
rs560471208 740 dbSNP
rs150076892 741 dbSNP
rs756093501 760 dbSNP
rs546253823 763 dbSNP
rs1010341165 765 dbSNP
rs1324886843 765 dbSNP
rs1285817499 768 dbSNP
rs1045592890 771 dbSNP
rs189848851 773 dbSNP
rs1318439340 782 dbSNP
rs1383503039 784 dbSNP
rs1174150339 786 dbSNP
rs1175404784 792 dbSNP
rs955559901 793 dbSNP
rs1008195996 795 dbSNP
rs1431332420 802 dbSNP
rs1003977003 803 dbSNP
rs116049111 805 dbSNP
rs1491307284 806 dbSNP
rs1217293132 807 dbSNP
rs140657102 807 dbSNP
rs141876107 807 dbSNP
rs1491535829 807 dbSNP
rs57178955 807 dbSNP
rs755200867 807 dbSNP
rs776290566 807 dbSNP
rs1339327288 811 dbSNP
rs1035016699 812 dbSNP
rs1441032018 813 dbSNP
rs1338332289 814 dbSNP
rs1335740510 815 dbSNP
rs962012643 816 dbSNP
rs1452931213 821 dbSNP
rs77071529 822 dbSNP
rs1308327013 823 dbSNP
rs1352699345 824 dbSNP
rs1403542436 825 dbSNP
rs1283171971 826 dbSNP
rs200271101 827 dbSNP
rs1220970641 828 dbSNP
rs1270993469 832 dbSNP
rs1307072778 834 dbSNP
rs1420189102 837 dbSNP
rs1168567136 843 dbSNP
rs994105848 845 dbSNP
rs1383479137 847 dbSNP
rs1183152327 854 dbSNP
rs964363736 857 dbSNP
rs1025530171 870 dbSNP
rs79257174 871 dbSNP
rs920122335 875 dbSNP
rs983960560 882 dbSNP
rs1274403548 886 dbSNP
rs951519902 902 dbSNP
rs1018477865 908 dbSNP
rs982512005 914 dbSNP
rs1353573037 923 dbSNP
rs141703512 928 dbSNP
rs563549947 928 dbSNP
rs770224936 928 dbSNP
rs1306770391 930 dbSNP
rs182453871 932 dbSNP
rs1355029043 933 dbSNP
rs1246001665 935 dbSNP
rs1330748146 936 dbSNP
rs1363750813 937 dbSNP
rs1478322533 937 dbSNP
rs527880985 938 dbSNP
rs1377412302 939 dbSNP
rs2436185 940 dbSNP
rs570821909 942 dbSNP
rs1175843163 948 dbSNP
rs758327580 970 dbSNP
rs1233828895 971 dbSNP
rs936603641 986 dbSNP
rs1290373227 987 dbSNP
rs988361928 990 dbSNP
rs1053676599 991 dbSNP
rs915487057 1003 dbSNP
rs1372068962 1005 dbSNP
rs1373706827 1011 dbSNP
rs1281104415 1024 dbSNP
rs779607338 1032 dbSNP
rs946914742 1034 dbSNP
rs1302947671 1035 dbSNP
rs892323014 1037 dbSNP
rs1332127553 1044 dbSNP
rs1302588835 1046 dbSNP
rs1439230801 1060 dbSNP
rs1269004010 1061 dbSNP
rs1367667647 1061 dbSNP
rs539726122 1065 dbSNP
rs1157119600 1070 dbSNP
rs1400343542 1075 dbSNP
rs138674275 1076 dbSNP
rs1160704257 1079 dbSNP
rs771225719 1084 dbSNP
rs1199493413 1095 dbSNP
rs1042202837 1105 dbSNP
rs142871451 1116 dbSNP
rs905306393 1119 dbSNP
rs939466946 1122 dbSNP
rs1276984691 1123 dbSNP
rs1056930380 1130 dbSNP
rs1283912859 1144 dbSNP
rs537809209 1150 dbSNP
rs897834192 1160 dbSNP
rs554371786 1161 dbSNP
rs1346057043 1170 dbSNP
rs1025599141 1171 dbSNP
rs1452032626 1173 dbSNP
rs1177702483 1181 dbSNP
rs1200898988 1182 dbSNP
rs11547103 1192 dbSNP
rs1018299429 1197 dbSNP
rs964378526 1198 dbSNP
rs995727472 1199 dbSNP
rs367805278 1204 dbSNP
rs951549304 1205 dbSNP
rs1201520613 1208 dbSNP
rs768097752 1215 dbSNP
rs540071172 1216 dbSNP
rs1263531982 1221 dbSNP
rs1225223920 1229 dbSNP
rs976546351 1229 dbSNP
rs112840242 1230 dbSNP
rs1162971591 1238 dbSNP
rs1362908539 1245 dbSNP
rs956408741 1251 dbSNP
rs970528055 1257 dbSNP
rs11547104 1258 dbSNP
rs1450732430 1260 dbSNP
rs1405760335 1268 dbSNP
rs1337832767 1271 dbSNP
rs980918249 1271 dbSNP
rs987765683 1272 dbSNP
rs186899984 1274 dbSNP
rs915518180 1275 dbSNP
rs1428650969 1276 dbSNP
rs926324219 1283 dbSNP
rs1421040883 1293 dbSNP
rs1391901852 1295 dbSNP
rs1181297415 1301 dbSNP
rs1443663753 1305 dbSNP
rs1243472555 1307 dbSNP
rs1205375337 1309 dbSNP
rs936300784 1316 dbSNP
rs989399916 1317 dbSNP
rs546115448 1319 dbSNP
rs1345146557 1320 dbSNP
rs939477943 1325 dbSNP
rs945269221 1328 dbSNP
rs1051644533 1346 dbSNP
rs1056571166 1357 dbSNP
rs1382375987 1361 dbSNP
rs562910227 1377 dbSNP
rs1398221740 1383 dbSNP
rs929330142 1389 dbSNP
rs1298046378 1390 dbSNP
rs944164956 1402 dbSNP
rs146992823 1404 dbSNP
rs1161157462 1412 dbSNP
rs548965232 1413 dbSNP
rs888392054 1413 dbSNP
rs1249564483 1419 dbSNP
rs899862942 1419 dbSNP
rs866938222 1422 dbSNP
rs542158148 1426 dbSNP
rs899666681 1426 dbSNP
rs113950159 1430 dbSNP
rs1292847313 1430 dbSNP
rs747749000 1430 dbSNP
rs995425512 1438 dbSNP
rs1334278618 1445 dbSNP
rs1027199104 1450 dbSNP
rs1464406904 1454 dbSNP
rs113879881 1455 dbSNP
rs1300742206 1461 dbSNP
rs1004417054 1465 dbSNP
rs1403863262 1466 dbSNP
rs1249355772 1474 dbSNP
rs1365676778 1476 dbSNP
rs1164574501 1487 dbSNP
rs1442316660 1488 dbSNP
rs1362962744 1490 dbSNP
rs1159631606 1505 dbSNP
rs527748481 1510 dbSNP
rs1021931954 1511 dbSNP
rs770104416 1512 dbSNP
rs1490189663 1517 dbSNP
rs1388133971 1521 dbSNP
rs980567683 1524 dbSNP
rs773593243 1536 dbSNP
rs1211817763 1540 dbSNP
rs926836398 1544 dbSNP
rs1368737685 1547 dbSNP
rs547616019 1548 dbSNP
rs1331825999 1555 dbSNP
rs1157208701 1558 dbSNP
rs960936707 1562 dbSNP
rs113739584 1564 dbSNP
rs1223447532 1564 dbSNP
rs929359883 1564 dbSNP
rs992322583 1564 dbSNP
rs1383845514 1565 dbSNP
rs989180793 1566 dbSNP
rs1458668560 1570 dbSNP
rs1426953554 1571 dbSNP
rs1175532735 1575 dbSNP
rs913569021 1578 dbSNP
rs2246077 1580 dbSNP
rs1201154716 1593 dbSNP
rs533488040 1598 dbSNP
rs987780181 1599 dbSNP
rs1323216695 1600 dbSNP
rs911741681 1602 dbSNP
rs943173557 1607 dbSNP
rs1452069454 1609 dbSNP
rs10833249 1611 dbSNP
rs899892012 1613 dbSNP
rs771452357 1614 dbSNP
rs774937310 1616 dbSNP
rs931388229 1626 dbSNP
rs570284497 1653 dbSNP
rs1223385817 1660 dbSNP
rs1039631463 1668 dbSNP
rs1277571491 1671 dbSNP
rs191749440 1678 dbSNP
rs1224699645 1684 dbSNP
rs997998435 1688 dbSNP
rs1048420232 1694 dbSNP
rs1436832469 1711 dbSNP
rs1403579557 1712 dbSNP
rs1335863855 1713 dbSNP
rs1050872865 1724 dbSNP
rs548135697 1726 dbSNP
rs1474434770 1727 dbSNP
rs878955537 1733 dbSNP
rs1372583875 1734 dbSNP
rs1004483620 1735 dbSNP
rs1025626227 1739 dbSNP
rs906707235 1743 dbSNP
rs1002750471 1745 dbSNP
rs767668802 1753 dbSNP
rs1203480119 1765 dbSNP
rs11025396 1769 dbSNP
rs1443798750 1772 dbSNP
rs967750711 1788 dbSNP
rs1338096503 1793 dbSNP
rs1010642910 1794 dbSNP
rs760931413 1799 dbSNP
rs1380184258 1815 dbSNP
rs1314069268 1818 dbSNP
rs1453189898 1837 dbSNP
rs764983046 1841 dbSNP
rs1342057556 1854 dbSNP
rs1326695735 1857 dbSNP
rs1180020624 1864 dbSNP
rs750230218 1871 dbSNP
rs911759132 1876 dbSNP
rs1431831852 1877 dbSNP
rs964581222 1891 dbSNP
rs1183358416 1900 dbSNP
rs1473295104 1901 dbSNP
rs1033973215 1905 dbSNP
rs1180232616 1908 dbSNP
rs1437780527 1917 dbSNP
rs866352618 1926 dbSNP
rs992355012 1927 dbSNP
rs919437627 1933 dbSNP
rs1290653256 1936 dbSNP
rs143601868 1938 dbSNP
rs984875575 1957 dbSNP
rs1441366996 1971 dbSNP
rs564183112 1979 dbSNP
rs554055018 1980 dbSNP
rs909254135 1998 dbSNP
rs2246191 2007 dbSNP
rs1048436782 2012 dbSNP
rs1363808932 2012 dbSNP
rs1163091867 2014 dbSNP
rs1406200718 2021 dbSNP
rs1389896231 2024 dbSNP
rs544842991 2026 dbSNP
rs1157239868 2029 dbSNP
rs2246192 2036 dbSNP
rs1046650418 2045 dbSNP
rs1253249546 2049 dbSNP
rs575314042 2052 dbSNP
rs933923708 2061 dbSNP
rs1267597165 2078 dbSNP
rs1410264812 2086 dbSNP
rs556499690 2088 dbSNP
rs1221784911 2090 dbSNP
rs1050948657 2099 dbSNP
rs1002458774 2103 dbSNP
rs1009323440 2104 dbSNP
rs1055326378 2105 dbSNP
rs893963791 2107 dbSNP
rs1193702850 2111 dbSNP
rs1043519638 2118 dbSNP
rs1010672084 2124 dbSNP
rs1020690975 2127 dbSNP
rs966403499 2143 dbSNP
rs1351876454 2147 dbSNP
rs1316673294 2151 dbSNP
rs569915029 2152 dbSNP
rs1008946160 2154 dbSNP
rs1018604276 2157 dbSNP
rs1479756256 2158 dbSNP
rs965025085 2159 dbSNP
rs1427964895 2162 dbSNP
rs1191311648 2163 dbSNP
rs1489256703 2165 dbSNP
rs1267324926 2166 dbSNP
rs1240063014 2170 dbSNP
rs1214655045 2183 dbSNP
rs1013863460 2184 dbSNP
rs974611977 2189 dbSNP
rs779981541 2196 dbSNP
rs1201634821 2202 dbSNP
rs761028576 2212 dbSNP
rs1300638558 2221 dbSNP
rs576257014 2223 dbSNP
rs1460584365 2238 dbSNP
rs984173713 2239 dbSNP
rs541871189 2240 dbSNP
rs1389781510 2241 dbSNP
rs940114596 2242 dbSNP
rs1468668480 2246 dbSNP
rs1176136531 2253 dbSNP
rs1046875550 2258 dbSNP
rs1371450388 2262 dbSNP
rs1430126957 2274 dbSNP
rs1185536026 2278 dbSNP
rs531476194 2282 dbSNP
rs938293161 2286 dbSNP
rs923284440 2293 dbSNP
rs1386134919 2297 dbSNP
rs931897170 2300 dbSNP
rs1256578505 2304 dbSNP
rs1055354747 2307 dbSNP
rs1212171208 2310 dbSNP
rs1051589523 2315 dbSNP
rs933286328 2323 dbSNP
rs748655100 2337 dbSNP
rs893994467 2356 dbSNP
rs986689850 2374 dbSNP
rs1301964624 2381 dbSNP
rs1332293861 2388 dbSNP
rs117525441 2390 dbSNP
rs199803985 2394 dbSNP
rs945253298 2396 dbSNP
rs72510027 2397 dbSNP
rs10528545 2398 dbSNP
rs3842256 2398 dbSNP
rs66483453 2399 dbSNP
rs1468054115 2423 dbSNP
rs1352215321 2428 dbSNP
rs572497289 2429 dbSNP
rs1169198477 2439 dbSNP
rs113971350 2447 dbSNP
rs1043929369 2450 dbSNP
rs903628296 2454 dbSNP
rs1443723267 2456 dbSNP
rs1256601678 2460 dbSNP
rs1207669232 2463 dbSNP
rs1183486163 2469 dbSNP
rs1479645472 2473 dbSNP
rs185011013 2496 dbSNP
rs543049378 2497 dbSNP
rs1343121378 2498 dbSNP
rs369356478 2512 dbSNP
rs765985049 2516 dbSNP
rs1210948643 2518 dbSNP
rs1019049405 2525 dbSNP
rs1398286688 2530 dbSNP
rs147535802 2531 dbSNP
rs896155240 2531 dbSNP
rs1188045267 2534 dbSNP
rs1371885380 2547 dbSNP
rs1161213427 2550 dbSNP
rs1423642106 2551 dbSNP
rs900151478 2553 dbSNP
rs1166702950 2554 dbSNP
rs1267156534 2557 dbSNP
rs996069199 2559 dbSNP
rs1390953583 2561 dbSNP
rs1407239568 2565 dbSNP
rs533353385 2566 dbSNP
rs1182826868 2567 dbSNP
rs1027490924 2568 dbSNP
rs147786889 2574 dbSNP
rs1483383606 2574 dbSNP
rs1220467013 2581 dbSNP
rs1488309089 2581 dbSNP
rs951889185 2582 dbSNP
rs144289302 2606 dbSNP
rs1266375969 2620 dbSNP
rs77513637 2621 dbSNP
rs114061720 2622 dbSNP
rs188678034 2625 dbSNP
rs568045295 2628 dbSNP
rs1229554629 2629 dbSNP
rs1351757127 2631 dbSNP
rs964885265 2632 dbSNP
rs1392830969 2640 dbSNP
rs78606106 2645 dbSNP
rs1030384139 2650 dbSNP
rs1295055066 2656 dbSNP
rs879222521 2670 dbSNP
rs1451281713 2671 dbSNP
rs954745824 2676 dbSNP
rs749674609 2679 dbSNP
rs547522272 2681 dbSNP
rs913842611 2695 dbSNP
rs927966879 2706 dbSNP
rs1197417976 2714 dbSNP
rs979343435 2721 dbSNP
rs1268394235 2722 dbSNP
rs925124274 2723 dbSNP
rs1485059955 2724 dbSNP
rs937818823 2731 dbSNP
rs1209853503 2738 dbSNP
rs1331893465 2739 dbSNP
rs1280801785 2754 dbSNP
rs938001805 2758 dbSNP
rs1331190728 2772 dbSNP
rs1302867542 2773 dbSNP
rs1380196215 2777 dbSNP
rs1387569542 2778 dbSNP
rs74499419 2794 dbSNP
rs1310213360 2803 dbSNP
rs896228770 2805 dbSNP
rs1170885078 2807 dbSNP
rs915460544 2809 dbSNP
rs946944487 2812 dbSNP
rs1426986560 2822 dbSNP
rs775033349 2823 dbSNP
rs1047416307 2829 dbSNP
rs752258904 2837 dbSNP
rs1466628641 2841 dbSNP
rs1267717083 2846 dbSNP
rs539663990 2853 dbSNP
rs556357313 2854 dbSNP
rs1345056687 2856 dbSNP
rs1257262787 2863 dbSNP
rs1224758201 2868 dbSNP
rs1364064420 2869 dbSNP
rs72927483 2873 dbSNP
rs1380329967 2889 dbSNP
rs1248714949 2890 dbSNP
rs1037918556 2909 dbSNP
rs77373075 2911 dbSNP
rs777792088 2912 dbSNP
rs1169200415 2924 dbSNP
rs555521322 2930 dbSNP
rs1181953462 2934 dbSNP
rs1428059803 2943 dbSNP
rs1389846077 2947 dbSNP
rs995765007 2949 dbSNP
rs1169479339 2950 dbSNP
rs996352688 2952 dbSNP
rs1413392711 2958 dbSNP
rs1422985622 2961 dbSNP
rs550865298 2971 dbSNP
rs139512158 2983 dbSNP
rs764365148 2984 dbSNP
rs1455582739 2996 dbSNP
rs1257616920 3003 dbSNP
rs1193645175 3006 dbSNP
rs753949458 3021 dbSNP
rs193094908 3025 dbSNP
rs1230171121 3030 dbSNP
rs757153526 3046 dbSNP
rs1004741196 3053 dbSNP
rs1388717037 3056 dbSNP
rs1283407132 3057 dbSNP
rs1448642661 3060 dbSNP
rs1020252338 3062 dbSNP
rs1015202911 3064 dbSNP
rs1408013128 3066 dbSNP
rs868129347 3089 dbSNP
rs1370031135 3090 dbSNP
rs971228433 3090 dbSNP
rs8526 3091 dbSNP
rs1412043559 3093 dbSNP
rs1035070243 3099 dbSNP
rs766113647 3106 dbSNP
rs1229203311 3107 dbSNP
rs1315272051 3109 dbSNP
rs1327603802 3114 dbSNP
rs751546938 3117 dbSNP
rs1228302396 3121 dbSNP
rs1251948248 3122 dbSNP
rs754877332 3130 dbSNP
rs915242020 3142 dbSNP
rs780744828 3143 dbSNP
rs1228729823 3166 dbSNP
rs530687729 3175 dbSNP
rs978353543 3175 dbSNP
rs1349892045 3177 dbSNP
rs1331285884 3180 dbSNP
rs557853550 3188 dbSNP
rs569461361 3194 dbSNP
rs753582745 3197 dbSNP
rs941672942 3199 dbSNP
rs1406266187 3208 dbSNP
rs1040536135 3209 dbSNP
rs1237069844 3211 dbSNP
rs1483708849 3213 dbSNP
rs1038395639 3216 dbSNP
rs900753393 3219 dbSNP
rs996774109 3222 dbSNP
rs757083321 3224 dbSNP
rs1183765302 3227 dbSNP
rs1471521339 3230 dbSNP
rs1476835296 3239 dbSNP
rs900284084 3240 dbSNP
rs1221854258 3242 dbSNP
rs1051864932 3254 dbSNP
rs1266032561 3262 dbSNP
rs1208004080 3270 dbSNP
rs890591918 3271 dbSNP
rs931732087 3283 dbSNP
rs1010293141 3288 dbSNP
rs1020284856 3291 dbSNP
rs1048741769 3293 dbSNP
rs1158308689 3304 dbSNP
rs577681989 3309 dbSNP
rs969130063 3318 dbSNP
rs1457147455 3337 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084066. RNA binding protein: AGO2. Condition:CLIP_noemetine_SantaCruzAb HITS-CLIP data was present in GSM1084067. RNA binding protein: AGO2. Condition:CLIP_emetine_SantaCruzAb HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084081. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SantaCruzAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000360655.4 | 3UTR | AAAAGAGAGACAGAGAGAAAAAAAAAAAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000360655.4 | 3UTR | GAGAGAAAAAAAAAAAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084066
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SantaCruzAb
Location of target site ENST00000360655.4 | 3UTR | GAGAGAAAAAAAAAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1084067
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_SantaCruzAb
Location of target site ENST00000360655.4 | 3UTR | GAGAGAAAAAAAAAAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000360655.4 | 3UTR | CAGAGAGAAAAAAAAAAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084081
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_SantaCruzAb
Location of target site ENST00000360655.4 | 3UTR | GAAAAAAAAAAAGAGAAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
50 hsa-miR-2117 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT080059 TGIF1 TGFB induced factor homeobox 1 2 2
MIRT253245 ZNF264 zinc finger protein 264 2 4
MIRT279706 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT359344 TMEM167A transmembrane protein 167A 2 2
MIRT465598 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT479860 CCDC6 coiled-coil domain containing 6 2 2
MIRT512413 KIAA0391 KIAA0391 2 2
MIRT525342 TUBGCP4 tubulin gamma complex associated protein 4 2 2
MIRT528092 UCHL3 ubiquitin C-terminal hydrolase L3 2 2
MIRT529254 TRIM4 tripartite motif containing 4 2 4
MIRT550782 VAV3 vav guanine nucleotide exchange factor 3 2 2
MIRT554467 SAMD12 sterile alpha motif domain containing 12 2 2
MIRT560164 ZNF286A zinc finger protein 286A 2 2
MIRT562613 BTF3L4 basic transcription factor 3 like 4 2 2
MIRT568507 ARF1 ADP ribosylation factor 1 2 2
MIRT571536 ZNF286B zinc finger protein 286B 2 2
MIRT609660 ITIH5 inter-alpha-trypsin inhibitor heavy chain family member 5 2 2
MIRT612022 PAK6 p21 (RAC1) activated kinase 6 2 8
MIRT615677 NAV2 neuron navigator 2 2 2
MIRT616035 SCO1 SCO1, cytochrome c oxidase assembly protein 2 2
MIRT617771 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT628757 MX2 MX dynamin like GTPase 2 2 4
MIRT635089 AKIRIN1 akirin 1 2 2
MIRT638261 SIX1 SIX homeobox 1 2 2
MIRT638492 NNT nicotinamide nucleotide transhydrogenase 2 2
MIRT639400 NEURL1B neuralized E3 ubiquitin protein ligase 1B 2 2
MIRT641791 USP32 ubiquitin specific peptidase 32 2 2
MIRT642309 FPR1 formyl peptide receptor 1 2 2
MIRT645902 LRIF1 ligand dependent nuclear receptor interacting factor 1 2 2
MIRT649701 ZNF175 zinc finger protein 175 2 2
MIRT656848 KLF13 Kruppel like factor 13 2 2
MIRT659911 CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 2 2
MIRT667275 NAV1 neuron navigator 1 2 2
MIRT674145 ZNF793 zinc finger protein 793 2 2
MIRT692839 C1orf50 chromosome 1 open reading frame 50 2 2
MIRT698520 TFRC transferrin receptor 2 2
MIRT698731 STX6 syntaxin 6 2 4
MIRT700931 PDPK1 3-phosphoinositide dependent protein kinase 1 2 2
MIRT706080 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 2
MIRT710008 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 2
MIRT711059 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT711285 PSME3 proteasome activator subunit 3 2 2
MIRT716172 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT716761 TRABD2A TraB domain containing 2A 2 2
MIRT718683 FZD2 frizzled class receptor 2 2 2
MIRT719675 SPDYE1 speedy/RINGO cell cycle regulator family member E1 2 2
MIRT721610 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT722188 DNAJC9 DnaJ heat shock protein family (Hsp40) member C9 2 2
MIRT725156 SEC62 SEC62 homolog, preprotein translocation factor 2 2
MIRT725239 PDE1B phosphodiesterase 1B 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-2117 Ascorbate approved 54670067 Microarray Metastatic melanoma cell lines 25202679 2014 up-regualted
miR-2117 Ascorbate approved 54670067 Microarray Metastatic melanoma cell lines 25202679 2014 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-2117 Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-2117 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-2117 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM43)
hsa-miR-2117 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-2117 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-2117 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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