miRTarBase - #MIRT617186


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pre-miRNA Information
pre-miRNA hsa-mir-6769b   
Genomic Coordinates chr1: 206474803 - 206474864
Description Homo sapiens miR-6769b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6769b-3p
Sequence 42| CCCUCUCUGUCCCACCCAUAG |62
Evidence Experimental
Experiments Meta-analysis
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN26671848 9 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs555627187 3 dbSNP
rs782102173 4 dbSNP
rs201952639 7 dbSNP
rs782001154 9 dbSNP
rs1488064450 15 dbSNP
rs782111367 16 dbSNP
rs370859899 18 dbSNP
rs1305197911 19 dbSNP
Putative Targets

Gene Information
Gene Symbol GOSR2   
Synonyms Bos1, EPM6, GS27
Description golgi SNAP receptor complex member 2
Transcript NM_004287   
Other Transcripts NM_001012511 , NM_054022   
Expression
Putative miRNA Targets on GOSR2
3'UTR of GOSR2
(miRNA target sites are highlighted)		 
>GOSR2|NM_004287|3'UTR
   1 GCCAGCCACGCTCAGTGGCTGAACAGCATTCCCACAGCCTGCAAGTGTGTGTGTGTGTGAAAGAGAGAGGGGGGCCCAGA
  81 GGCCGCCTTTTGAAATGTTTGCCTGTCTGAACTGTGAAGACACTTGGGAGTGATTGTGGTCTAATTTCCAACCTGCTCTG
 161 TTTTCTGTGACATCTTGGAGGGGGAGCTAGTGCCACCACCATGCGCGGTGCTTAGGAAATGAAAGAAGTCCCGGGTCTGT
 241 CTCTCTCACTCTCGCTCTCACTGGGGGAGGGAAAGAATGGCTTTGGTGGCTTTGTTCACATAGCTGATGCGTGCCCTGGG
 321 AAGGTGTCCACAGTGAGCCCTGTGTGCAGGACTGTCCACACGGTTCACACCTTGTCACCATCAGGCCTTTCTGGCTCCTG
 401 ATAGGGTGGAGCAAAAGTGGAAAGGAAAGGAAAGAGGCCTTTTCTCACAGCCATTATATTAAATAGTAGGTCGATTCACA
 481 TCCTCGTGCTCCTGGCCACCCTCCCCTGTGCCTCAGTGACATGTAGATGACTGACTGCCAATACTTGTCACCATTCCCTG
 561 GAAGCAGCTACCTAGGGGAAACAAGATGTAGTGCTATTGCCGATAACAAGTAAGATTTTCCACACTACAGCTGGGTGTTT
 641 CTCTTTTCTAAAGTGAGGCCAGTGTTATTTCCCGGGAGTGTTCAGTCTTGACCCTAGTCACTGATTTTTTCTAGTTGTTA
 721 ATAGAGTGGTTGGCTTTTAAGGTTCAGAGACTGTGGCTTGGCACCTGCGCCCAGGCTTTGTGGGCCTTTGCCCCTTAGAA
 801 AGTAGCTGTAGGCAAAGATTTGTGATTTTCCAATTACAGTCTCAGCTCTAGTTTTAGTATCTCTAATTCTTTGGTTCCCT
 881 TCTCTTCCCTGAAATATATTAGCACCTGCCAGCCAGGCCCTCATTTTGCCCAGCCAGTGTGGGCAGATCCCACCGTGGAG
 961 ACATCTGTAGTGTGTATGTCCTTGTAACACTCTGTTTTCAGGGACTACAACCTTTTTCCTTCTGTGACCAGCCCCGGATT
1041 CAGGCTGTACTAATACCAGGTATATTGTGGAATTTAGTATAAAGGCCAATCTGTCCTGAAGTCCATCTAATGTGGTGAAT
1121 CACTGAAAGTCTCAGAAAGACCTGGTTAGTGTATGTTCTCATTTACCACAGGCCTACCAGCCCTGGGCACAGCAGCTTCA
1201 TGGCAAGACATAAAATGACACTCAAAATCCTTCAGATCTGGAAACCGGCTCAGTATTAACCCTACCTTTGGTTGTCCTGC
1281 CCTACCTGCTCTGTTAGTTTCTTGTTGCTTGAACTGTCTTCTGTCTTATTTCCCTTCCTTTCTGTGTTCCTCTTCACCTC
1361 TCTTGTTCCCCTCCCCGCTGCTCTGTAGTCATGTTGGTCCTTTCAGGCACCTCTGTGGCATAGCTCCCCTTTGGTAAGTT
1441 TTCTTAATTGTCATAGATTAACTGAGTTTCCTGGATGCTAATTTCACACTTTCGGTTGGAGGAGATCTCCATTGTTCCTA
1521 CCCCTCCGGGCCAAATGGGCCCCAGGTTTCCAAGGAAGGAGCAATCTGTGACTCCTAAAATGGGTTGGGGCCCTGCCAGA
1601 GTTAAAGCAGTGACTGGAGGGTGGACTGGGGGGTTGCAGCATCTTTAGACCTAGATCTGTCTAACTCTGGGGAGGCACAT
1681 TGACATTTCCATTACACACAGCACTGCTGCGGTGCCAGGGACCTAGCGCAGGACTTTTGGTAATCCATAAAATGGATTCT
1761 GAGACTGCGACGGCAAGGCTGTCCTGTCCCCCAGGCACCCAAGGATCCTGCCAGACAGCACACTTTGGAGGAAGGTCTGC
1841 AGGGAGCAGCTGAGCCATTTGTTCTTGAACTCTGGGAGGCAGAAGTCCCCGCACCCATCATGCGTGGACTGATAGGACAT
1921 CTTTTCGTGGTGTGCACCAGTGCTTTCCACACTTGACAGTGGTTGGCTTTGATGAACCCTCATGCTGCACCTTCAGAGCC
2001 AGTCCTCTAGTTTGGAATAAAAATTGCAGAGGTGGTTTTTGGGTCTTTACCACCTGCGGCTGGTGGACAGCAGCCAGTGT
2081 GTCTGGACACCCAGGGGCATTGAGACTGCATGTTGTCACATGACCACTTCTCTTCACACATCTGCTTTCAGTGCCTGGTG
2161 AAAAATAGACCTTGGCCTAACAGTGTGACTCTCTCCACCGCCTCAGTGTAGGGAAGGGTCCAGGCCAGGGAAGGAGCACC
2241 CTCTAGTGGAGGCGGGGGTGAATTCTTAGGTCGAGCTGATGCAAGAAACTCCGGTAGCCAGCCTCTGTGACCTTGTACAT
2321 GAGTTTGGTGTGCCTATTGTGATTTAAAACAGGTGGGTTATCAAGAGGAACTTGAGATCTCTTTATTACATGGACATTTA
2401 CTTCAGGGGGACCACTGTAAGAAAAGCCAAACTCCAAGACCAAGTAAGTTAGAGGAGTCTTGATTTTTTAGACTTCACTG
2481 CGGAGTTCTGTACACCCTTTGCCCTGATGAATTTGAATGGGTTTGATTTGCAAATTTGGATTTACACCCATTGTTTTGGA
2561 AGCACATCAGCTGAATAAAGTTGAGGTTTATTTTATTTAGAAAATCACATTTTGTAAAAGAATTCGATATTCATTTTTAT
2641 AACTAATGGCCCCCTTTTTTTATGTTTCTAGGCCAGAGATTCTCAAACACTGCTCCATGGCCAGGGGCTGGGCTGGCTGC
2721 TTCAGAAGCAGTGGGGAAGCTTTTTAAAATTACATATTCCTGGGGCCTACCCCAGATCTGAATTAGAACCTTTTTTAAAT
2801 CTCTAAGGTGATTTTATTTTATTTTTTATTTTTGAGACAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATC
2881 TTGGCTCACTGCATCCTCTGCCTCCTGGGTTCAGGTGATCCTCATACCTCAGCCTCCTGAGTAGCTGGAACTACAAGTGT
2961 GTGCCACCATGTCTGGCTAATTTTTTTTTTTTTTTTGTATTTTTTAGTAGAGACAGGGTTTTACTATGTTGACCAGATTG
3041 GTCTTAAACTCCTGGCCTCAAGTGATCTGCCTGCTTCGGCCTCCCAAAGTTCTAGGGTTACAGGTGTTAGCCACTGTACC
3121 TGGCCTCTAAGGTGATTCTGATGTGTGTATTTTGGAACCACTGTCTCCTAGACAGAAAGCTTCTGTCTCAAAGATGATCA
3201 CATTGGTGTAAAGAGCAAAACTTGTTAAGTCCAAAATAAATTCTTACTGTTTATATCCTAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaUACCCACCCUGUCUCUCCc 5'
            :|| |||  | ||||||| 
Target 5' gtGTGTGTGAAAGAGAGAGGg 3'
 51 - 71 159.00 -21.30
2 
miRNA  3' gauacCCACCCUGUCUCUCcc 5'
               |||  | |||:|||  
Target 5' aggaaGGTCTG-CAGGGAGca 3'
 1829 - 1848 115.00 -11.90
3 
miRNA  3' gaUACCCACCCU---GUCUCUCCc 5'
            :|||   |||    | ||||| 
Target 5' aaGTGGAAAGGAAAGGAAAGAGGc 3'
 415 - 438 115.00 -12.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1057497 1 ClinVar
323827 19 ClinVar
323828 287 ClinVar
323829 287 ClinVar
323830 302 ClinVar
323831 333 ClinVar
323832 413 ClinVar
323833 805 ClinVar
323834 1063 ClinVar
323835 1068 ClinVar
323836 1106 ClinVar
323837 1116 ClinVar
323838 1278 ClinVar
323839 1378 ClinVar
323840 1447 ClinVar
323841 1520 ClinVar
323842 1656 ClinVar
323843 1680 ClinVar
323844 1704 ClinVar
323845 1712 ClinVar
323846 1734 ClinVar
585946 1796 ClinVar
383352 1824 ClinVar
323847 2058 ClinVar
323848 2069 ClinVar
323849 2189 ClinVar
323850 2193 ClinVar
323851 2196 ClinVar
323852 2214 ClinVar
323853 2254 ClinVar
323854 2292 ClinVar
323855 2293 ClinVar
323856 2294 ClinVar
323857 2337 ClinVar
323858 2338 ClinVar
323859 2343 ClinVar
323860 2574 ClinVar
323861 2590 ClinVar
COSN30751947 7 COSMIC
COSN31613325 28 COSMIC
COSN30106031 46 COSMIC
COSN30600169 59 COSMIC
COSN30137356 75 COSMIC
COSN31591558 75 COSMIC
COSN31564548 83 COSMIC
COSN30173536 85 COSMIC
COSN13727108 86 COSMIC
COSN30157152 93 COSMIC
COSN31582075 104 COSMIC
COSN30504656 129 COSMIC
COSN20114045 297 COSMIC
COSN15887931 473 COSMIC
COSN20150759 907 COSMIC
COSN20093297 1426 COSMIC
COSN26992629 1667 COSMIC
COSN1720442 1707 COSMIC
COSN28557334 1712 COSMIC
COSN8866304 1734 COSMIC
COSN1197613 1773 COSMIC
COSM4925535 1796 COSMIC
COSM8511796 1810 COSMIC
COSM8369647 1820 COSMIC
COSM5386535 1827 COSMIC
COSM8150643 1843 COSMIC
COSM7436208 1852 COSMIC
COSM7436209 1853 COSMIC
COSN22229121 1856 COSMIC
COSN31569202 1880 COSMIC
COSN26977740 1892 COSMIC
COSN13727116 1905 COSMIC
COSN31506099 1911 COSMIC
COSN30170809 1941 COSMIC
COSN30498686 1976 COSMIC
COSN31525706 2025 COSMIC
COSN7436597 2025 COSMIC
COSN21577811 2189 COSMIC
COSN25099969 2535 COSMIC
COSN17058658 2675 COSMIC
COSN1720443 2806 COSMIC
COSN20150760 3034 COSMIC
rs11874 1068 GWAS
rs1052586 2338 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs762088678 5 dbSNP
rs779509783 10 dbSNP
rs1407750568 11 dbSNP
rs571655190 15 dbSNP
rs772447527 16 dbSNP
rs914681617 18 dbSNP
rs778066395 19 dbSNP
rs1440339547 21 dbSNP
rs1321647935 24 dbSNP
rs774052056 24 dbSNP
rs747240567 25 dbSNP
rs1216769357 29 dbSNP
rs770999907 31 dbSNP
rs776841160 35 dbSNP
rs376614852 36 dbSNP
rs527870181 42 dbSNP
rs571009629 45 dbSNP
rs765433603 45 dbSNP
rs775385642 47 dbSNP
rs762839548 48 dbSNP
rs1162233423 50 dbSNP
rs1474626687 51 dbSNP
rs751372410 52 dbSNP
rs1050239691 55 dbSNP
rs761433402 58 dbSNP
rs1306797323 59 dbSNP
rs1218141598 62 dbSNP
rs1423713817 62 dbSNP
rs1476809349 73 dbSNP
rs910401705 75 dbSNP
rs1256205502 76 dbSNP
rs375452158 81 dbSNP
rs1040340635 85 dbSNP
rs949794175 86 dbSNP
rs1482484484 89 dbSNP
rs566202193 104 dbSNP
rs1213288777 106 dbSNP
rs981195322 107 dbSNP
rs924261034 115 dbSNP
rs766998927 124 dbSNP
rs897736098 125 dbSNP
rs1326386952 134 dbSNP
rs1302549202 144 dbSNP
rs1054141992 150 dbSNP
rs1365910822 154 dbSNP
rs1257510607 155 dbSNP
rs1428419423 170 dbSNP
rs1167997887 182 dbSNP
rs1425132950 184 dbSNP
rs1400503779 195 dbSNP
rs368780514 197 dbSNP
rs184197582 202 dbSNP
rs1463570727 205 dbSNP
rs1372476247 206 dbSNP
rs1048723073 207 dbSNP
rs1434749969 208 dbSNP
rs1175270670 209 dbSNP
rs1458400184 213 dbSNP
rs1240213840 216 dbSNP
rs367735669 233 dbSNP
rs1012679747 234 dbSNP
rs1257157298 235 dbSNP
rs1023112805 237 dbSNP
rs1310887620 240 dbSNP
rs761117888 242 dbSNP
rs1303149471 243 dbSNP
rs891001127 250 dbSNP
rs537489434 253 dbSNP
rs1361233477 255 dbSNP
rs1398068845 258 dbSNP
rs1002984564 260 dbSNP
rs1389231378 261 dbSNP
rs1395130405 263 dbSNP
rs1173159954 265 dbSNP
rs529000124 276 dbSNP
rs1320117562 278 dbSNP
rs1219260534 287 dbSNP
rs78693564 287 dbSNP
rs990769151 288 dbSNP
rs1176987081 291 dbSNP
rs376212419 297 dbSNP
rs139209716 298 dbSNP
rs8078556 302 dbSNP
rs754380153 311 dbSNP
rs985583638 312 dbSNP
rs755362352 324 dbSNP
rs189095245 329 dbSNP
rs886053079 333 dbSNP
rs1265892284 335 dbSNP
rs944554880 335 dbSNP
rs1236429993 337 dbSNP
rs1334740464 338 dbSNP
rs991787122 340 dbSNP
rs1397225296 343 dbSNP
rs1040226915 347 dbSNP
rs1477879223 350 dbSNP
rs1312171737 357 dbSNP
rs919051435 362 dbSNP
rs1190069582 364 dbSNP
rs1023551346 370 dbSNP
rs929244962 388 dbSNP
rs7209721 396 dbSNP
rs1469828275 402 dbSNP
rs1369223323 405 dbSNP
rs1422100754 412 dbSNP
rs886053080 413 dbSNP
rs765279001 418 dbSNP
rs1284333904 419 dbSNP
rs1344375994 426 dbSNP
rs924334643 432 dbSNP
rs1349541428 435 dbSNP
rs1273390272 438 dbSNP
rs887467904 445 dbSNP
rs201923580 446 dbSNP
rs955808922 447 dbSNP
rs1353006964 454 dbSNP
rs765576738 455 dbSNP
rs1400714787 457 dbSNP
rs1044181454 471 dbSNP
rs139652892 472 dbSNP
rs1365808370 477 dbSNP
rs1165199917 480 dbSNP
rs1221140741 486 dbSNP
rs1003035029 487 dbSNP
rs1417248721 492 dbSNP
rs1194398576 500 dbSNP
rs1031804398 504 dbSNP
rs775729401 512 dbSNP
rs1240820204 523 dbSNP
rs181200484 528 dbSNP
rs562694673 530 dbSNP
rs1290214555 537 dbSNP
rs1211258827 539 dbSNP
rs1214851533 540 dbSNP
rs1022272650 549 dbSNP
rs1272001900 553 dbSNP
rs867280023 557 dbSNP
rs954097897 559 dbSNP
rs1218659553 573 dbSNP
rs1342325710 589 dbSNP
rs1268313543 591 dbSNP
rs985854411 592 dbSNP
rs1331461685 594 dbSNP
rs143006022 595 dbSNP
rs1325859077 597 dbSNP
rs1438994873 603 dbSNP
rs1288806365 608 dbSNP
rs912384800 612 dbSNP
rs1019748144 623 dbSNP
rs965453562 625 dbSNP
rs1418048977 626 dbSNP
rs972777839 628 dbSNP
rs866232087 630 dbSNP
rs545114578 646 dbSNP
rs1248823207 648 dbSNP
rs1192079502 661 dbSNP
rs1466876435 664 dbSNP
rs929106688 665 dbSNP
rs866284809 672 dbSNP
rs984747848 674 dbSNP
rs375928886 675 dbSNP
rs1270869298 681 dbSNP
rs1213918673 693 dbSNP
rs1345551283 694 dbSNP
rs1276414221 705 dbSNP
rs1478840863 711 dbSNP
rs1191428060 714 dbSNP
rs1370577032 721 dbSNP
rs948448117 722 dbSNP
rs1044037609 727 dbSNP
rs1049522134 735 dbSNP
rs1328185972 750 dbSNP
rs763106058 758 dbSNP
rs1415557881 760 dbSNP
rs906839727 766 dbSNP
rs887821621 769 dbSNP
rs1013566736 770 dbSNP
rs1454084789 776 dbSNP
rs1023245597 777 dbSNP
rs752904810 785 dbSNP
rs1178852780 791 dbSNP
rs886053081 805 dbSNP
rs565223505 812 dbSNP
rs1230686556 817 dbSNP
rs1002973350 821 dbSNP
rs1052775916 826 dbSNP
rs1404667767 826 dbSNP
rs1282338461 834 dbSNP
rs1491331720 836 dbSNP
rs1031804404 837 dbSNP
rs891983328 839 dbSNP
rs955755714 844 dbSNP
rs1438618199 849 dbSNP
rs989950257 852 dbSNP
rs1371382799 857 dbSNP
rs1012142669 867 dbSNP
rs1448798514 870 dbSNP
rs1361450040 878 dbSNP
rs1021909327 880 dbSNP
rs764318232 888 dbSNP
rs953763216 890 dbSNP
rs985769133 899 dbSNP
rs1361571057 903 dbSNP
rs912456841 904 dbSNP
rs890030132 906 dbSNP
rs1176160459 907 dbSNP
rs575866889 911 dbSNP
rs758552649 914 dbSNP
rs1036830924 918 dbSNP
rs1208632908 929 dbSNP
rs1485264328 930 dbSNP
rs918454275 936 dbSNP
rs1019633248 938 dbSNP
rs929377524 939 dbSNP
rs1315385369 946 dbSNP
rs965341818 955 dbSNP
rs527999974 956 dbSNP
rs1357432933 962 dbSNP
rs1452842809 973 dbSNP
rs1292053427 979 dbSNP
rs1414715808 983 dbSNP
rs751298104 990 dbSNP
rs1300460289 991 dbSNP
rs1452033748 993 dbSNP
rs1025715146 1004 dbSNP
rs543193253 1005 dbSNP
rs985021778 1008 dbSNP
rs1456155768 1012 dbSNP
rs1180322183 1021 dbSNP
rs1157893639 1022 dbSNP
rs1380681064 1030 dbSNP
rs909171157 1036 dbSNP
rs948647426 1037 dbSNP
rs1474851594 1041 dbSNP
rs1161393759 1049 dbSNP
rs1012889801 1051 dbSNP
rs1415823886 1051 dbSNP
rs1188091300 1060 dbSNP
rs16941324 1063 dbSNP
rs11874 1068 dbSNP
rs1222583714 1070 dbSNP
rs750940698 1078 dbSNP
rs1444831499 1080 dbSNP
rs528933584 1089 dbSNP
rs549057785 1090 dbSNP
rs780111337 1106 dbSNP
rs1052826518 1107 dbSNP
rs778601184 1107 dbSNP
rs758391 1116 dbSNP
rs1294414568 1117 dbSNP
rs1244438987 1119 dbSNP
rs879295353 1126 dbSNP
rs1043617227 1132 dbSNP
rs185023068 1152 dbSNP
rs1460438098 1161 dbSNP
rs189647673 1169 dbSNP
rs1172430630 1173 dbSNP
rs565433765 1177 dbSNP
rs1426588614 1178 dbSNP
rs1260784522 1182 dbSNP
rs972682826 1208 dbSNP
rs559653076 1211 dbSNP
rs1251333397 1212 dbSNP
rs1256836446 1217 dbSNP
rs146088780 1225 dbSNP
rs534098104 1235 dbSNP
rs140094353 1239 dbSNP
rs1441663056 1247 dbSNP
rs952905657 1248 dbSNP
rs777419699 1249 dbSNP
rs1372773966 1250 dbSNP
rs1185082117 1251 dbSNP
rs747774727 1252 dbSNP
rs1439599227 1256 dbSNP
rs573784384 1266 dbSNP
rs1005594978 1275 dbSNP
rs1396588321 1276 dbSNP
rs577505377 1278 dbSNP
rs556611457 1283 dbSNP
rs969888815 1285 dbSNP
rs948819044 1287 dbSNP
rs1239186778 1289 dbSNP
rs1473065828 1294 dbSNP
rs980007951 1324 dbSNP
rs1176567982 1327 dbSNP
rs576494888 1334 dbSNP
rs1393561309 1335 dbSNP
rs959730636 1338 dbSNP
rs1173103547 1348 dbSNP
rs1252769138 1351 dbSNP
rs1194099408 1362 dbSNP
rs1420327558 1371 dbSNP
rs1480608986 1373 dbSNP
rs1257067757 1377 dbSNP
rs180777362 1378 dbSNP
rs564952656 1386 dbSNP
rs1346152382 1387 dbSNP
rs1300890099 1411 dbSNP
rs912856482 1413 dbSNP
rs1335922786 1422 dbSNP
rs947130675 1427 dbSNP
rs1308546844 1440 dbSNP
rs1389137492 1443 dbSNP
rs572361575 1447 dbSNP
rs1313390193 1454 dbSNP
rs1436422289 1460 dbSNP
rs1022231663 1462 dbSNP
rs541327375 1465 dbSNP
rs1470646577 1489 dbSNP
rs561470914 1493 dbSNP
rs185331275 1494 dbSNP
rs550139085 1495 dbSNP
rs972630836 1495 dbSNP
rs1484939270 1496 dbSNP
rs901416881 1512 dbSNP
rs562578450 1513 dbSNP
rs1217745078 1518 dbSNP
rs4968286 1520 dbSNP
rs1262094115 1523 dbSNP
rs1236319330 1525 dbSNP
rs983930988 1535 dbSNP
rs1293290543 1540 dbSNP
rs1047508698 1545 dbSNP
rs888420782 1566 dbSNP
rs1416553551 1577 dbSNP
rs1353428886 1580 dbSNP
rs551363541 1592 dbSNP
rs1401042828 1595 dbSNP
rs916408040 1609 dbSNP
rs1157031515 1610 dbSNP
rs1453230661 1611 dbSNP
rs1023697304 1617 dbSNP
rs1343825118 1626 dbSNP
rs1418671866 1628 dbSNP
rs1198554315 1629 dbSNP
rs571274611 1630 dbSNP
rs1001312571 1632 dbSNP
rs1194900886 1633 dbSNP
rs1192868961 1639 dbSNP
rs1263486710 1640 dbSNP
rs1203005219 1643 dbSNP
rs1349430576 1645 dbSNP
rs928622225 1648 dbSNP
rs1234543395 1651 dbSNP
rs373602816 1655 dbSNP
rs116123534 1656 dbSNP
rs117210496 1660 dbSNP
rs536431584 1665 dbSNP
rs1315866775 1669 dbSNP
rs149765350 1680 dbSNP
rs552799196 1681 dbSNP
rs745773590 1692 dbSNP
rs1433573932 1700 dbSNP
rs144662292 1704 dbSNP
rs11657819 1712 dbSNP
rs758598475 1713 dbSNP
rs889988218 1724 dbSNP
rs1435666003 1726 dbSNP
rs1168578385 1729 dbSNP
rs758392 1734 dbSNP
rs1192814234 1746 dbSNP
rs1464251827 1749 dbSNP
rs148511622 1753 dbSNP
rs1437859879 1759 dbSNP
rs767214928 1766 dbSNP
rs374383310 1769 dbSNP
rs755660289 1771 dbSNP
rs377308635 1772 dbSNP
rs369557972 1773 dbSNP
rs1214642191 1774 dbSNP
rs758885350 1774 dbSNP
rs778355377 1777 dbSNP
rs747267756 1780 dbSNP
rs1019401230 1782 dbSNP
rs1226288180 1786 dbSNP
rs1372129726 1787 dbSNP
rs766295758 1787 dbSNP
rs757651569 1790 dbSNP
rs1348551415 1791 dbSNP
rs751561082 1793 dbSNP
rs1416447582 1795 dbSNP
rs147434599 1796 dbSNP
rs1354465457 1799 dbSNP
rs140685046 1801 dbSNP
rs1330220539 1802 dbSNP
rs1252646889 1805 dbSNP
rs1394476738 1807 dbSNP
rs1411713322 1807 dbSNP
rs1167520050 1808 dbSNP
rs746138669 1809 dbSNP
rs1194735899 1812 dbSNP
rs1274628174 1817 dbSNP
rs769834243 1821 dbSNP
rs142261376 1824 dbSNP
rs749239417 1827 dbSNP
rs1195272876 1834 dbSNP
rs768422581 1835 dbSNP
rs774352164 1836 dbSNP
rs1205194071 1837 dbSNP
rs767466315 1838 dbSNP
rs575057184 1840 dbSNP
rs941354762 1841 dbSNP
rs760466734 1842 dbSNP
rs765974207 1846 dbSNP
rs753229227 1850 dbSNP
rs1313366080 1856 dbSNP
rs1374646378 1858 dbSNP
rs1394005184 1865 dbSNP
rs1005916066 1870 dbSNP
rs1232541593 1871 dbSNP
rs1297364152 1873 dbSNP
rs754519349 1874 dbSNP
rs1226123732 1888 dbSNP
rs764465941 1891 dbSNP
rs752132148 1892 dbSNP
rs1280620376 1893 dbSNP
rs969218389 1895 dbSNP
rs757598206 1901 dbSNP
rs373654893 1902 dbSNP
rs1483130222 1904 dbSNP
rs746086938 1905 dbSNP
rs756390829 1906 dbSNP
rs1432607041 1908 dbSNP
rs369846922 1912 dbSNP
rs1221648069 1920 dbSNP
rs928695868 1926 dbSNP
rs1035492845 1928 dbSNP
rs1230615095 1931 dbSNP
rs1180829314 1939 dbSNP
rs1218941030 1940 dbSNP
rs1262512186 1962 dbSNP
rs895622094 1963 dbSNP
rs1208336650 1966 dbSNP
rs1432881074 1982 dbSNP
rs371640338 1988 dbSNP
rs960134992 1989 dbSNP
rs1010586280 2002 dbSNP
rs1225920970 2020 dbSNP
rs1371820514 2021 dbSNP
rs988735525 2026 dbSNP
rs1020181282 2033 dbSNP
rs968816926 2038 dbSNP
rs913255711 2054 dbSNP
rs368549324 2058 dbSNP
rs1311256668 2059 dbSNP
rs774617192 2069 dbSNP
rs886053082 2069 dbSNP
rs1358308669 2079 dbSNP
rs1159578092 2083 dbSNP
rs1379546260 2089 dbSNP
rs1405694008 2090 dbSNP
rs1158405902 2094 dbSNP
rs1018075758 2100 dbSNP
rs749194360 2103 dbSNP
rs911380299 2110 dbSNP
rs1242992995 2121 dbSNP
rs1218380990 2141 dbSNP
rs1315565826 2167 dbSNP
rs1454997135 2167 dbSNP
rs1268029634 2169 dbSNP
rs976463573 2172 dbSNP
rs1234483469 2173 dbSNP
rs942816225 2174 dbSNP
rs182061396 2184 dbSNP
rs1395609467 2188 dbSNP
rs553512648 2189 dbSNP
rs886053083 2189 dbSNP
rs900883895 2189 dbSNP
rs1432616946 2192 dbSNP
rs993925648 2192 dbSNP
rs545130658 2193 dbSNP
rs888149319 2194 dbSNP
rs565638240 2196 dbSNP
rs754879964 2200 dbSNP
rs983463506 2201 dbSNP
rs886053084 2214 dbSNP
rs1422052174 2218 dbSNP
rs1485079394 2229 dbSNP
rs1247832620 2233 dbSNP
rs527270223 2237 dbSNP
rs1214809960 2238 dbSNP
rs111422753 2246 dbSNP
rs969291639 2247 dbSNP
rs1244150259 2250 dbSNP
rs1389401271 2252 dbSNP
rs1213065392 2253 dbSNP
rs1003308685 2254 dbSNP
rs886053085 2254 dbSNP
rs960082404 2258 dbSNP
rs964099817 2260 dbSNP
rs1045072046 2273 dbSNP
rs778733242 2274 dbSNP
rs1172034579 2278 dbSNP
rs1426391243 2278 dbSNP
rs939448245 2282 dbSNP
rs1056448481 2283 dbSNP
rs895674554 2284 dbSNP
rs1306774732 2286 dbSNP
rs186093347 2292 dbSNP
rs79673308 2293 dbSNP
rs77706742 2294 dbSNP
rs1158810347 2295 dbSNP
rs1488201676 2300 dbSNP
rs746719239 2303 dbSNP
rs1304534382 2306 dbSNP
rs1000481244 2307 dbSNP
rs1372978203 2313 dbSNP
rs1299067579 2316 dbSNP
rs1041200558 2320 dbSNP
rs1373365051 2329 dbSNP
rs1299396814 2333 dbSNP
rs569751775 2337 dbSNP
rs1052586 2338 dbSNP
rs61745471 2343 dbSNP
rs1029401139 2365 dbSNP
rs1441863978 2368 dbSNP
rs1393697166 2378 dbSNP
rs1198722468 2379 dbSNP
rs1252679973 2382 dbSNP
rs1160472234 2391 dbSNP
rs142588426 2398 dbSNP
rs1482804168 2405 dbSNP
rs1455956255 2406 dbSNP
rs951662692 2412 dbSNP
rs1164475135 2429 dbSNP
rs982964579 2431 dbSNP
rs1349735662 2435 dbSNP
rs1254051150 2449 dbSNP
rs561744945 2455 dbSNP
rs1005603447 2464 dbSNP
rs1044755161 2464 dbSNP
rs565869072 2465 dbSNP
rs543252765 2466 dbSNP
rs1034811729 2472 dbSNP
rs369035114 2480 dbSNP
rs941625762 2482 dbSNP
rs374027388 2483 dbSNP
rs1172370302 2485 dbSNP
rs776008064 2493 dbSNP
rs1157651887 2495 dbSNP
rs1366049187 2495 dbSNP
rs1010305900 2497 dbSNP
rs926642278 2498 dbSNP
rs939335218 2518 dbSNP
rs554685692 2520 dbSNP
rs968848300 2529 dbSNP
rs1311949629 2531 dbSNP
rs1319830224 2533 dbSNP
rs1242751378 2535 dbSNP
rs1199656552 2537 dbSNP
rs1351201752 2545 dbSNP
rs1262395289 2549 dbSNP
rs1226534830 2563 dbSNP
rs979130567 2564 dbSNP
rs1327817160 2565 dbSNP
rs1056500586 2572 dbSNP
rs1275121888 2572 dbSNP
rs886053086 2574 dbSNP
rs1234679540 2578 dbSNP
rs1338335069 2580 dbSNP
rs913978618 2581 dbSNP
rs886053087 2590 dbSNP
rs945908979 2604 dbSNP
rs1387648293 2607 dbSNP
rs1319083542 2619 dbSNP
rs1457198820 2620 dbSNP
rs528859500 2626 dbSNP
rs904321403 2627 dbSNP
rs922747146 2631 dbSNP
rs1000130393 2635 dbSNP
rs1178093503 2640 dbSNP
rs1447330955 2646 dbSNP
rs1263617744 2647 dbSNP
rs1206684730 2649 dbSNP
rs1464392380 2650 dbSNP
rs1256134270 2655 dbSNP
rs1039618782 2656 dbSNP
rs930165998 2662 dbSNP
rs1422553525 2663 dbSNP
rs1166382764 2665 dbSNP
rs543771907 2668 dbSNP
rs1464598085 2669 dbSNP
rs1168102361 2673 dbSNP
rs557484958 2675 dbSNP
rs1328518366 2676 dbSNP
rs760047379 2679 dbSNP
rs765683708 2683 dbSNP
rs997839169 2687 dbSNP
rs577512323 2697 dbSNP
rs1462348773 2698 dbSNP
rs951162894 2707 dbSNP
rs1434923785 2713 dbSNP
rs1395850539 2714 dbSNP
rs1328586374 2722 dbSNP
rs1403652023 2732 dbSNP
rs1390153695 2735 dbSNP
rs941124149 2741 dbSNP
rs1168667234 2753 dbSNP
rs1302011529 2754 dbSNP
rs1476524489 2755 dbSNP
rs1391718052 2759 dbSNP
rs546460488 2762 dbSNP
rs1017112806 2764 dbSNP
rs1253528338 2768 dbSNP
rs939251667 2771 dbSNP
rs1449336373 2772 dbSNP
rs1288557189 2773 dbSNP
rs1195963192 2792 dbSNP
rs963178207 2797 dbSNP
rs564958170 2800 dbSNP
rs1272117687 2803 dbSNP
rs1228108205 2804 dbSNP
rs1372243554 2805 dbSNP
rs892395336 2811 dbSNP
rs1009790183 2816 dbSNP
rs1434981057 2817 dbSNP
rs1330541629 2822 dbSNP
rs1329634796 2839 dbSNP
rs1411796625 2842 dbSNP
rs763378903 2843 dbSNP
rs191980794 2845 dbSNP
rs540994552 2846 dbSNP
rs960726930 2853 dbSNP
rs1000319845 2864 dbSNP
rs1245557204 2870 dbSNP
rs1190714570 2873 dbSNP
rs550727825 2875 dbSNP
rs1477228524 2876 dbSNP
rs913852678 2879 dbSNP
rs142652226 2890 dbSNP
rs1428738870 2896 dbSNP
rs1348995095 2905 dbSNP
rs1175162278 2908 dbSNP
rs1029891529 2919 dbSNP
rs1357228147 2932 dbSNP
rs34758846 2933 dbSNP
rs549803134 2951 dbSNP
rs1444441763 2954 dbSNP
rs935815384 2957 dbSNP
rs1039671694 2958 dbSNP
rs1348754776 2960 dbSNP
rs535222911 2961 dbSNP
rs1052574156 2967 dbSNP
rs1307609931 2970 dbSNP
rs1415651013 2971 dbSNP
rs1313440302 2972 dbSNP
rs577066118 2979 dbSNP
rs1412609269 2981 dbSNP
rs1491065712 2981 dbSNP
rs199529204 2981 dbSNP
rs556885353 2981 dbSNP
rs566143081 2981 dbSNP
rs1402773318 2988 dbSNP
rs983317860 2993 dbSNP
rs1276353373 2996 dbSNP
rs761382200 2997 dbSNP
rs914079290 2998 dbSNP
rs1442258008 2999 dbSNP
rs1285543312 3000 dbSNP
rs945748365 3000 dbSNP
rs1287823481 3003 dbSNP
rs1300785103 3007 dbSNP
rs1357601825 3008 dbSNP
rs1310817890 3009 dbSNP
rs910062061 3009 dbSNP
rs1213420407 3027 dbSNP
rs1445509653 3035 dbSNP
rs1281697218 3037 dbSNP
rs1318840449 3038 dbSNP
rs751819235 3050 dbSNP
rs201728209 3056 dbSNP
rs1409052171 3065 dbSNP
rs1488230812 3070 dbSNP
rs1475283687 3078 dbSNP
rs151011422 3079 dbSNP
rs1243328522 3085 dbSNP
rs997892827 3087 dbSNP
rs142169063 3088 dbSNP
rs1190276646 3093 dbSNP
rs1047779 3118 dbSNP
rs1463939536 3125 dbSNP
rs1268123749 3130 dbSNP
rs938989984 3131 dbSNP
rs1323629989 3135 dbSNP
rs1310808721 3140 dbSNP
rs1227991393 3144 dbSNP
rs1378106970 3148 dbSNP
rs1056074141 3153 dbSNP
rs1003981117 3155 dbSNP
rs182911438 3169 dbSNP
rs534809599 3175 dbSNP
rs1043942303 3181 dbSNP
rs1296488483 3191 dbSNP
rs1002318416 3192 dbSNP
rs1000670523 3193 dbSNP
rs1404410192 3196 dbSNP
rs1431493686 3197 dbSNP
rs1190904738 3200 dbSNP
rs144457797 3201 dbSNP
rs1365698385 3203 dbSNP
rs960946778 3208 dbSNP
rs1247925416 3215 dbSNP
rs992336185 3216 dbSNP
rs913974876 3217 dbSNP
rs1039840325 3222 dbSNP
rs1263778332 3222 dbSNP
rs899931912 3226 dbSNP
rs1237006779 3231 dbSNP
rs1308302248 3232 dbSNP
rs1277117100 3233 dbSNP
rs568368193 3235 dbSNP
rs537502331 3243 dbSNP
rs1362821296 3244 dbSNP
rs147793949 3248 dbSNP
rs531169787 3249 dbSNP
rs1029672742 3259 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_ControlB_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell Control B ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gaUACCCACCCUGUCUCUCcc 5'
            :|| ||| || ||||||  
Target 5' guGUGUGUGUGAAAGAGAGag 3'
 		3 - 23
Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084078. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset Chi_ControlB_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell Control B
Location of target site ENST00000576910.2 | 3UTR | GUGUGUGUGUGUGAAAGAGAGAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000576910.2 | 3UTR | UGCAAGUGUGUGUGUGUGUGAAAGAGAGAGGGGGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000576910.2 | 3UTR | UGCAAGUGUGUGUGUGUGUGAAAGAGAGAGGGGGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1084073
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_AbnovaAb
Location of target site ENST00000576910.2 | 3UTR | UGCAAGUGUGUGUGUGUGUGAAAGAGAGAGGGGGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1084078
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep2_AbnovaAb
Location of target site ENST00000576910.2 | 3UTR | GCAAGUGUGUGUGUGUGUGAAAGAGAGAGGGGGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000576910.2 | 3UTR | GCAAGUGUGUGUGUGUGUGAAAGAGAGAGGGGGGCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
209 hsa-miR-6769b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT181753 UHMK1 U2AF homology motif kinase 1 2 2
MIRT287119 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT395372 CDC42EP4 CDC42 effector protein 4 2 4
MIRT472533 NACC1 nucleus accumbens associated 1 2 4
MIRT472611 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT482405 ADRB1 adrenoceptor beta 1 2 10
MIRT492330 SETD1B SET domain containing 1B 2 2
MIRT499238 VAV3 vav guanine nucleotide exchange factor 3 2 6
MIRT512274 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT534548 RUNX1 runt related transcription factor 1 2 2
MIRT535374 PEX5L peroxisomal biogenesis factor 5 like 2 2
MIRT535424 PDZD8 PDZ domain containing 8 2 2
MIRT539329 AHSA2 activator of HSP90 ATPase homolog 2 2 4
MIRT569350 EFHC1 EF-hand domain containing 1 2 2
MIRT576116 Klf6 Kruppel-like factor 6 2 2
MIRT607241 LINS lines homolog 1 2 4
MIRT607364 ASAH2 N-acylsphingosine amidohydrolase 2 2 4
MIRT609572 CATSPER4 cation channel sperm associated 4 2 2
MIRT610045 SERPINA3 serpin family A member 3 2 2
MIRT610284 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 2 2
MIRT610302 KLHL21 kelch like family member 21 2 2
MIRT610393 FOXE1 forkhead box E1 2 2
MIRT610432 ASAH2B N-acylsphingosine amidohydrolase 2B 2 2
MIRT610510 BARHL2 BarH like homeobox 2 2 2
MIRT611818 FCRL4 Fc receptor like 4 2 2
MIRT612755 MYOCD myocardin 2 2
MIRT613698 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT613917 POU3F1 POU class 3 homeobox 1 2 2
MIRT615153 URGCP-MRPS24 URGCP-MRPS24 readthrough 2 2
MIRT615201 CLUAP1 clusterin associated protein 1 2 2
MIRT615338 ABCC12 ATP binding cassette subfamily C member 12 2 2
MIRT616706 UBXN2A UBX domain protein 2A 2 2
MIRT617186 GOSR2 golgi SNAP receptor complex member 2 2 4
MIRT617526 SORCS2 sortilin related VPS10 domain containing receptor 2 2 2
MIRT617596 NUDT5 nudix hydrolase 5 2 4
MIRT617763 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT618613 SHOX short stature homeobox 2 2
MIRT619301 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT619515 TXLNB taxilin beta 2 2
MIRT619925 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT619942 C8orf33 chromosome 8 open reading frame 33 2 2
MIRT620025 NFAM1 NFAT activating protein with ITAM motif 1 2 2
MIRT620554 C10orf10 chromosome 10 open reading frame 10 2 4
MIRT620752 CCR5 C-C motif chemokine receptor 5 (gene/pseudogene) 2 2
MIRT621798 TMEM233 transmembrane protein 233 2 2
MIRT621843 TGFBR3 transforming growth factor beta receptor 3 2 2
MIRT622693 PLSCR1 phospholipid scramblase 1 2 2
MIRT622733 PITPNM3 PITPNM family member 3 2 2
MIRT623004 ONECUT3 one cut homeobox 3 2 2
MIRT623211 MTFR1L mitochondrial fission regulator 1 like 2 2
MIRT623771 GPR37L1 G protein-coupled receptor 37 like 1 2 2
MIRT624119 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT624150 DIAPH1 diaphanous related formin 1 2 2
MIRT624443 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT624855 ABI2 abl interactor 2 2 2
MIRT625311 SHISA6 shisa family member 6 2 2
MIRT625741 MTSS1 MTSS1, I-BAR domain containing 2 2
MIRT626292 ZNF85 zinc finger protein 85 2 2
MIRT627400 TMEM170A transmembrane protein 170A 2 2
MIRT627464 SYNRG synergin gamma 2 2
MIRT627913 KANSL1 KAT8 regulatory NSL complex subunit 1 2 2
MIRT636508 GDAP1L1 ganglioside induced differentiation associated protein 1 like 1 2 2
MIRT636910 KIAA0408 KIAA0408 2 2
MIRT637302 ACTN2 actinin alpha 2 2 2
MIRT638230 SOGA3 SOGA family member 3 2 2
MIRT639880 STC1 stanniocalcin 1 2 2
MIRT639999 PHF21B PHD finger protein 21B 2 2
MIRT640149 CEP104 centrosomal protein 104 2 2
MIRT640699 SKI SKI proto-oncogene 2 2
MIRT640911 RAB13 RAB13, member RAS oncogene family 2 2
MIRT641518 CREBBP CREB binding protein 2 2
MIRT641990 OXSR1 oxidative stress responsive 1 2 2
MIRT642635 EPPIN epididymal peptidase inhibitor 2 2
MIRT642744 TDRD6 tudor domain containing 6 2 2
MIRT642759 SDHAF2 succinate dehydrogenase complex assembly factor 2 2 2
MIRT642787 CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 2 2
MIRT643054 EPPIN-WFDC6 EPPIN-WFDC6 readthrough 2 2
MIRT643104 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT643316 TMEM151B transmembrane protein 151B 2 2
MIRT643715 ITK IL2 inducible T-cell kinase 2 2
MIRT644087 A4GALT alpha 1,4-galactosyltransferase (P blood group) 2 2
MIRT644112 SEL1L3 SEL1L family member 3 2 2
MIRT644377 ZNF286A zinc finger protein 286A 2 2
MIRT644408 FRMD6 FERM domain containing 6 2 2
MIRT644684 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT644744 CCDC174 coiled-coil domain containing 174 2 2
MIRT644876 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT645417 FAM110A family with sequence similarity 110 member A 2 2
MIRT645928 PLXNA3 plexin A3 2 2
MIRT646181 PTPN14 protein tyrosine phosphatase, non-receptor type 14 2 2
MIRT646554 TMCC2 transmembrane and coiled-coil domain family 2 2 2
MIRT647235 OR6A2 olfactory receptor family 6 subfamily A member 2 2 2
MIRT647263 PTGDR2 prostaglandin D2 receptor 2 2 2
MIRT647660 FOXL1 forkhead box L1 2 2
MIRT648284 TRAPPC2L trafficking protein particle complex 2 like 2 2
MIRT648493 CMBL carboxymethylenebutenolidase homolog 2 2
MIRT648963 TMEM45B transmembrane protein 45B 2 2
MIRT649511 RAB17 RAB17, member RAS oncogene family 2 2
MIRT650446 CPXM2 carboxypeptidase X, M14 family member 2 2 2
MIRT650712 KRT32 keratin 32 2 2
MIRT651069 ZNF518B zinc finger protein 518B 2 4
MIRT651090 ZNF516 zinc finger protein 516 2 2
MIRT651193 ZNF281 zinc finger protein 281 2 2
MIRT651330 ZCCHC2 zinc finger CCHC-type containing 2 2 2
MIRT651445 XKR4 XK related 4 2 2
MIRT651517 WNT4 Wnt family member 4 2 4
MIRT651694 VPS13D vacuolar protein sorting 13 homolog D 2 2
MIRT652173 TRIM66 tripartite motif containing 66 2 2
MIRT652432 TMEM239 transmembrane protein 239 2 2
MIRT652656 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT652707 THBS2 thrombospondin 2 2 2
MIRT652812 TBL2 transducin beta like 2 2 2
MIRT653350 SMG7 SMG7, nonsense mediated mRNA decay factor 2 2
MIRT653471 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT653658 SLC27A4 solute carrier family 27 member 4 2 2
MIRT654691 PSMB5 proteasome subunit beta 5 2 2
MIRT654735 PRLR prolactin receptor 2 2
MIRT654931 POLR3D RNA polymerase III subunit D 2 2
MIRT655209 PHAX phosphorylated adaptor for RNA export 2 2
MIRT655346 PCP4L1 Purkinje cell protein 4 like 1 2 2
MIRT655404 PANK1 pantothenate kinase 1 2 2
MIRT655482 PAK3 p21 (RAC1) activated kinase 3 2 2
MIRT655964 NDNF neuron derived neurotrophic factor 2 2
MIRT656017 MYPN myopalladin 2 2
MIRT656491 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT657151 ITGA1 integrin subunit alpha 1 2 2
MIRT657411 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 2
MIRT657608 GRID1 glutamate ionotropic receptor delta type subunit 1 2 2
MIRT658181 FBXO9 F-box protein 9 2 2
MIRT658932 DPY19L1 dpy-19 like C-mannosyltransferase 1 2 2
MIRT659028 DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2 2
MIRT659092 DENR density regulated re-initiation and release factor 2 2
MIRT659204 CYBB cytochrome b-245 beta chain 2 2
MIRT659718 CCDC93 coiled-coil domain containing 93 2 2
MIRT660185 BNC2 basonuclin 2 2 2
MIRT660805 AIFM2 apoptosis inducing factor, mitochondria associated 2 2 2
MIRT660900 ADCY6 adenylate cyclase 6 2 2
MIRT660925 ADAM19 ADAM metallopeptidase domain 19 2 2
MIRT661741 DTHD1 death domain containing 1 2 2
MIRT661998 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT662639 PKHD1L1 PKHD1 like 1 2 2
MIRT664338 RAB8A RAB8A, member RAS oncogene family 2 2
MIRT666743 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT667070 PANK3 pantothenate kinase 3 2 2
MIRT667925 IGLON5 IgLON family member 5 2 2
MIRT668488 ETV3 ETS variant 3 2 2
MIRT668610 EHD4 EH domain containing 4 2 2
MIRT669419 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT669652 ACSBG1 acyl-CoA synthetase bubblegum family member 1 2 2
MIRT674005 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT680447 SLCO5A1 solute carrier organic anion transporter family member 5A1 2 2
MIRT684326 GTF3C4 general transcription factor IIIC subunit 4 2 2
MIRT685625 C12orf49 chromosome 12 open reading frame 49 2 2
MIRT689978 ZNF185 zinc finger protein 185 with LIM domain 2 2
MIRT693962 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT698543 TFRC transferrin receptor 2 2
MIRT699982 RREB1 ras responsive element binding protein 1 2 2
MIRT702898 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT707383 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT708312 CDH8 cadherin 8 2 2
MIRT708406 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT709299 LDLRAD4 low density lipoprotein receptor class A domain containing 4 2 2
MIRT710326 STK40 serine/threonine kinase 40 2 2
MIRT710729 C19orf68 zinc finger SWIM-type containing 9 2 2
MIRT710970 CMKLR1 chemerin chemokine-like receptor 1 2 2
MIRT711178 EMCN endomucin 2 2
MIRT711590 SETD1A SET domain containing 1A 2 2
MIRT711611 LHX5 LIM homeobox 5 2 2
MIRT711701 GMPR guanosine monophosphate reductase 2 2
MIRT711850 AMOTL2 angiomotin like 2 2 2
MIRT712358 NAT14 N-acetyltransferase 14 (putative) 2 2
MIRT712377 MTPN myotrophin 2 2
MIRT712469 KCNC3 potassium voltage-gated channel subfamily C member 3 2 2
MIRT712839 RHOA ras homolog family member A 2 2
MIRT713592 ANKMY1 ankyrin repeat and MYND domain containing 1 2 2
MIRT713982 ASIC4 acid sensing ion channel subunit family member 4 2 2
MIRT714534 ZBTB39 zinc finger and BTB domain containing 39 2 2
MIRT714570 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 2 2
MIRT714610 EXO5 exonuclease 5 2 2
MIRT714943 ZNF330 zinc finger protein 330 2 2
MIRT715132 ACADL acyl-CoA dehydrogenase, long chain 2 2
MIRT716018 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT716204 TYW3 tRNA-yW synthesizing protein 3 homolog 2 2
MIRT716674 PPP6R1 protein phosphatase 6 regulatory subunit 1 2 2
MIRT717366 EDN2 endothelin 2 2 2
MIRT718110 CRTC1 CREB regulated transcription coactivator 1 2 2
MIRT718502 GYS1 glycogen synthase 1 2 2
MIRT719146 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT719415 B4GALNT3 beta-1,4-N-acetyl-galactosaminyltransferase 3 2 2
MIRT719986 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT720347 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT720452 SLC16A5 solute carrier family 16 member 5 2 2
MIRT720493 TMEM178B transmembrane protein 178B 2 2
MIRT720666 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT721091 CCBE1 collagen and calcium binding EGF domains 1 2 2
MIRT721334 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT721384 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT721508 CARHSP1 calcium regulated heat stable protein 1 2 2
MIRT721827 POU6F1 POU class 6 homeobox 1 2 2
MIRT722136 TTLL11 tubulin tyrosine ligase like 11 2 2
MIRT723070 GGA1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 2 2
MIRT723115 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT723374 ZNF470 zinc finger protein 470 2 2
MIRT724446 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT724528 ATP2B1 ATPase plasma membrane Ca2+ transporting 1 2 2
MIRT724643 PKDREJ polycystin family receptor for egg jelly 2 2
MIRT724711 CRAMP1L cramped chromatin regulator homolog 1 2 2
MIRT724750 ZNF391 zinc finger protein 391 2 2
MIRT724770 PSG4 pregnancy specific beta-1-glycoprotein 4 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6769b Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-mir-6769b Docetaxel+Cisplatin+5-Fluorouracil sensitive tissue (hypopharyngeal squamous cell carcinoma)
hsa-miR-6769b-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-6769b-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-6769b-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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