miRTarBase - #MIRT618519


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pre-miRNA Information
pre-miRNA hsa-mir-4532   
Genomic Coordinates chr20: 57895394 - 57895444
Description Homo sapiens miR-4532 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4532
Sequence 6| CCCCGGGGAGCCCGGCG |22
Evidence Experimental
Experiments Illumina
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SELPLG   
Synonyms CD162, CLA, PSGL-1, PSGL1
Description selectin P ligand
Transcript NM_003006   
Expression
Putative miRNA Targets on SELPLG
3'UTR of SELPLG
(miRNA target sites are highlighted)		 
>SELPLG|NM_003006|3'UTR
   1 CTCACTCTGCCATCTGTTTTGGCAAGACCCCACCTCCACGGGCTCTCCTGGGCCACCCCTGAGTGCCCAGACCCCATTCC
  81 ACAGCTCTGGGCTTCCTCGGAGACCCCTGGGGATGGGGATCTTCAGGGAAGGAACTCTGGCCACCCAAACAGGACAAGAG
 161 CAGCCTGGGGCCAAGCAGACGGGCAAGTGGAGCCACCTCTTTCCTCCCTCCGCGGATGAAGCCCAGCCACATTTCAGCCG
 241 AGGTCCAAGGCAGGAGGCCATTTACTTGAGACAGATTCTCTCCTTTTTCCTGTCCCCCATCTTCTCTGGGTCCCTCTAAC
 321 ATCTCCCATGGCTCTCCCCGCTTCTCCTGGTCACTGGAGTCTCCTCCCCATGTACCCAAGGAAGATGGAGCTCCCCCATC
 401 CCACACGCACTGCACTGCCATTGTCTTTTGGTTGCCATGGTCACCAAACAGGAAGTGGACATTCTAAGGGAGGAGTACTG
 481 AAGAGTGACGGACTTCTGAGGCTGTTTCCTGCTGCTCCTCTGACTTGGGGCAGCTTGGGTCTTCTTGGGCACCTCTCTGG
 561 GAAAACCCAGGGTGAGGTTCAGCCTGTGAGGGCTGGGATGGGTTTCGTGGGCCCAAGGGCAGACCTTTCTTTGGGACTGT
 641 GTGGACCAAGGAGCTTCCATCTAGTGACAAGTGACCCCCAGCTATCGCCTCTTGCCTTCCCCTGTGGCCACTTTCCAGGG
 721 TGGACTCTGTCTTGTTCACTGCAGTATCCCAACTGCAGGTCCAGTGCAGGCAATAAATATGTGATGGACAAACGATAGCG
 801 GAATCCTTCAAGGTTTCAAGGCTGTCTCCTTCAGGCAGCCTTCCCGGAATTCTCCATCCCTCAGTGCAGGATGGGGGCTG
 881 GTCCTCAGCTGTCTGCCCTCAGCCCCTGGCCCCCCAGGAAGCCTCTTTCATGGGCTGTTAGGTTGACTTCAGTTTTGCCT
 961 CTTGGACAACAGGGGGTCTTGTACATCCTTGGGTGACCAGGAAAAGTTCAGGCTATGGGGGGCCAAAGGGAGGGCTGCCC
1041 CTTCCCCACCAGTGACCACTTTATTCCACTTCCTCCATTACCCAGTTTTGGCCCACAGAGTTTGGTCCCCCCCAAACCTC
1121 GGACCAATATCCCTCTAAACATCAATCTATCCTCCTGTTAAAGAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gcGGCC-CGAGGGGCCCc 5'
            :||| |  |||:||| 
Target 5' ccTCGGAGACCCCTGGGg 3'
 95 - 112 131.00 -24.20
2 
miRNA  3' gcgGCCCGA-GGGGCCCc 5'
             |||||| :||:||| 
Target 5' ccaCGGGCTCTCCTGGGc 3'
 36 - 53 130.00 -28.10
3 
miRNA  3' gcGGCCCGAGGGGCCCc 5'
            || ||| |||| || 
Target 5' ccCCTGGCCCCCCAGGa 3'
 903 - 919 127.00 -18.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31575737 14 COSMIC
COSN28646194 39 COSMIC
COSN28648678 42 COSMIC
COSN30172134 47 COSMIC
COSN18858997 127 COSMIC
COSN15694302 181 COSMIC
COSN8339497 208 COSMIC
COSN24183319 218 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1419551842 4 dbSNP
rs112111856 9 dbSNP
rs777349631 13 dbSNP
rs1452589824 16 dbSNP
rs377104727 21 dbSNP
rs1198028698 22 dbSNP
rs770367060 23 dbSNP
rs753105310 27 dbSNP
rs182988667 28 dbSNP
rs1214157156 31 dbSNP
rs1352729362 34 dbSNP
rs755491231 35 dbSNP
rs1236081304 36 dbSNP
rs8179162 39 dbSNP
rs377034787 40 dbSNP
rs7311687 42 dbSNP
rs1364465493 44 dbSNP
rs1263996294 48 dbSNP
rs773569633 51 dbSNP
rs980056318 54 dbSNP
rs756660874 61 dbSNP
rs751915183 63 dbSNP
rs8179143 66 dbSNP
rs536498687 67 dbSNP
rs956140935 76 dbSNP
rs1050666 77 dbSNP
rs1471980781 82 dbSNP
rs753300141 98 dbSNP
rs141841274 99 dbSNP
rs1407635350 125 dbSNP
rs990615454 135 dbSNP
rs1412449962 139 dbSNP
rs1333057944 145 dbSNP
rs544139866 153 dbSNP
rs1310406053 155 dbSNP
rs1026888257 158 dbSNP
rs994779611 159 dbSNP
rs575091378 161 dbSNP
rs767414338 163 dbSNP
rs1284069834 164 dbSNP
rs1216055481 168 dbSNP
rs866343004 173 dbSNP
rs890540695 175 dbSNP
rs1269452919 179 dbSNP
rs901335862 180 dbSNP
rs1373270875 181 dbSNP
rs148497077 186 dbSNP
rs1461089093 188 dbSNP
rs1200028897 191 dbSNP
rs1430839566 194 dbSNP
rs940202160 206 dbSNP
rs932170631 209 dbSNP
rs78264936 211 dbSNP
rs549781358 212 dbSNP
rs531186284 213 dbSNP
rs900740027 214 dbSNP
rs1369083149 215 dbSNP
rs1409802382 222 dbSNP
rs538453425 231 dbSNP
rs1332927317 234 dbSNP
rs1434321611 237 dbSNP
rs1192277981 239 dbSNP
rs1274489419 240 dbSNP
rs936938311 241 dbSNP
rs923601709 245 dbSNP
rs978168775 251 dbSNP
rs1191406625 254 dbSNP
rs538987784 266 dbSNP
rs1323694286 271 dbSNP
rs1223170246 273 dbSNP
rs567401572 289 dbSNP
rs917060508 290 dbSNP
rs992625820 295 dbSNP
rs1476223425 297 dbSNP
rs1467769388 304 dbSNP
rs1166309464 307 dbSNP
rs949123861 309 dbSNP
rs1429457309 312 dbSNP
rs548656893 313 dbSNP
rs1393429753 314 dbSNP
rs1404092023 316 dbSNP
rs763280471 322 dbSNP
rs8179144 323 dbSNP
rs1031734660 327 dbSNP
rs959223129 327 dbSNP
rs1206360598 330 dbSNP
rs1364222307 332 dbSNP
rs746804781 334 dbSNP
rs1305543882 339 dbSNP
rs969107334 340 dbSNP
rs1026793520 368 dbSNP
rs973935256 377 dbSNP
rs1350195723 384 dbSNP
rs961601016 392 dbSNP
rs1209151659 396 dbSNP
rs182126081 406 dbSNP
rs1284404349 407 dbSNP
rs997500188 407 dbSNP
rs901392584 411 dbSNP
rs1449245913 430 dbSNP
rs1005333468 436 dbSNP
rs1370549463 441 dbSNP
rs1004313737 444 dbSNP
rs954808783 447 dbSNP
rs1030447384 449 dbSNP
rs775643038 466 dbSNP
rs1458841686 468 dbSNP
rs900646537 472 dbSNP
rs887289104 473 dbSNP
rs1440549305 474 dbSNP
rs1047456455 477 dbSNP
rs1338463626 479 dbSNP
rs1244027608 480 dbSNP
rs1053970661 481 dbSNP
rs572863619 483 dbSNP
rs1001090423 487 dbSNP
rs898820690 489 dbSNP
rs902765491 490 dbSNP
rs1201789666 496 dbSNP
rs571576634 498 dbSNP
rs1042052243 532 dbSNP
rs1177491933 534 dbSNP
rs1187485597 543 dbSNP
rs1364822797 552 dbSNP
rs1473618073 553 dbSNP
rs1044100534 558 dbSNP
rs1411318813 569 dbSNP
rs1437094183 585 dbSNP
rs948396332 585 dbSNP
rs1399839808 589 dbSNP
rs1395191976 594 dbSNP
rs769988184 597 dbSNP
rs917649452 604 dbSNP
rs1054779246 606 dbSNP
rs376560714 607 dbSNP
rs1323577168 609 dbSNP
rs1234995707 610 dbSNP
rs1453196322 613 dbSNP
rs1408345195 614 dbSNP
rs116676407 620 dbSNP
rs973882883 624 dbSNP
rs961317268 638 dbSNP
rs968866050 644 dbSNP
rs908490610 645 dbSNP
rs1028834970 648 dbSNP
rs746001542 649 dbSNP
rs1178536091 650 dbSNP
rs781604909 650 dbSNP
rs1211283144 653 dbSNP
rs1465726712 659 dbSNP
rs1168339100 667 dbSNP
rs781707264 670 dbSNP
rs1486622868 686 dbSNP
rs1407959734 687 dbSNP
rs975401602 688 dbSNP
rs150821083 690 dbSNP
rs771378290 702 dbSNP
rs1030353979 707 dbSNP
rs1298750052 709 dbSNP
rs8179146 724 dbSNP
rs1027146570 729 dbSNP
rs1275859883 742 dbSNP
rs778017416 743 dbSNP
rs1344722951 765 dbSNP
rs1203678715 767 dbSNP
rs994535648 769 dbSNP
rs1309497596 771 dbSNP
rs898878310 783 dbSNP
rs565426408 793 dbSNP
rs1012557539 794 dbSNP
rs543830491 799 dbSNP
rs1057056672 800 dbSNP
rs1427526620 805 dbSNP
rs1001479524 812 dbSNP
rs902752922 826 dbSNP
rs576358489 829 dbSNP
rs924431427 832 dbSNP
rs1043057834 839 dbSNP
rs1312796877 844 dbSNP
rs1433619999 845 dbSNP
rs1363851084 846 dbSNP
rs1013856258 858 dbSNP
rs1042878082 868 dbSNP
rs1274361994 873 dbSNP
rs1322910799 877 dbSNP
rs1224394345 891 dbSNP
rs896126960 909 dbSNP
rs531782506 910 dbSNP
rs947212521 911 dbSNP
rs1406724079 913 dbSNP
rs921336586 914 dbSNP
rs1447437477 916 dbSNP
rs1187773858 925 dbSNP
rs754605140 926 dbSNP
rs1425538418 929 dbSNP
rs965392700 933 dbSNP
rs937726130 937 dbSNP
rs191006450 943 dbSNP
rs1348830601 959 dbSNP
rs1457268997 961 dbSNP
rs1322154645 962 dbSNP
rs1385907281 984 dbSNP
rs1433884454 988 dbSNP
rs919718190 992 dbSNP
rs912585867 1000 dbSNP
rs1380306401 1002 dbSNP
rs1230556482 1007 dbSNP
rs1311144492 1013 dbSNP
rs982992771 1015 dbSNP
rs1476028209 1017 dbSNP
rs748947309 1019 dbSNP
rs951663323 1021 dbSNP
rs939875980 1022 dbSNP
rs1463760037 1023 dbSNP
rs1027199117 1029 dbSNP
rs1237883504 1033 dbSNP
rs1210058933 1045 dbSNP
rs143141074 1046 dbSNP
rs572274326 1047 dbSNP
rs553983048 1053 dbSNP
rs1472637019 1061 dbSNP
rs139125470 1062 dbSNP
rs577895599 1065 dbSNP
rs987096168 1070 dbSNP
rs1022701038 1074 dbSNP
rs371915948 1077 dbSNP
rs1334352118 1098 dbSNP
rs537886948 1100 dbSNP
rs1450562848 1105 dbSNP
rs779752615 1107 dbSNP
rs1229536157 1110 dbSNP
rs1056855901 1111 dbSNP
rs903064517 1112 dbSNP
rs1235599172 1113 dbSNP
rs1313757599 1114 dbSNP
rs964786087 1115 dbSNP
rs1207682430 1117 dbSNP
rs1236678430 1120 dbSNP
rs1043014322 1121 dbSNP
rs1032460855 1128 dbSNP
rs146994584 1130 dbSNP
rs967257401 1131 dbSNP
rs1471948039 1132 dbSNP
rs1172813895 1133 dbSNP
rs548669266 1141 dbSNP
rs921125191 1147 dbSNP
rs1039770793 1149 dbSNP
rs944157193 1153 dbSNP
rs755609864 1154 dbSNP
rs1441500412 1155 dbSNP
rs1387724654 1159 dbSNP
rs1290136926 1163 dbSNP
rs1347489256 1164 dbSNP
rs1207233137 1175 dbSNP
rs1217664067 1175 dbSNP
rs1342555303 1175 dbSNP
rs35331463 1175 dbSNP
rs58120028 1175 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gcggcccgagggGCCcc 5'
                      |||  
Target 5' ---------aagCGGag 3'
 		1 - 8
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000388962.3 | 3UTR | AAGCGGAGGGAGGUUGCAGUGAGCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
119 hsa-miR-4532 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT451366 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT451448 ZNF556 zinc finger protein 556 2 4
MIRT458550 CYP2B6 cytochrome P450 family 2 subfamily B member 6 2 2
MIRT460274 SLC26A2 solute carrier family 26 member 2 2 2
MIRT460365 TXNDC16 thioredoxin domain containing 16 2 4
MIRT460539 TM4SF5 transmembrane 4 L six family member 5 2 2
MIRT463626 YY1 YY1 transcription factor 2 2
MIRT468524 SERTAD2 SERTA domain containing 2 2 4
MIRT469966 PTPRF protein tyrosine phosphatase, receptor type F 2 8
MIRT470076 PTGES2 prostaglandin E synthase 2 2 2
MIRT474926 KCTD20 potassium channel tetramerization domain containing 20 2 2
MIRT479976 CARD10 caspase recruitment domain family member 10 2 2
MIRT485533 GPRIN1 G protein regulated inducer of neurite outgrowth 1 2 2
MIRT485939 ECSIT ECSIT signalling integrator 2 4
MIRT486421 RXRA retinoid X receptor alpha 2 2
MIRT487665 HPCAL1 hippocalcin like 1 2 4
MIRT488113 POU3F1 POU class 3 homeobox 1 2 4
MIRT490648 FEM1A fem-1 homolog A 2 2
MIRT491313 LRFN1 leucine rich repeat and fibronectin type III domain containing 1 2 2
MIRT491345 CPNE5 copine 5 2 2
MIRT492688 PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2 2
MIRT496879 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT499243 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT508211 SLC35E1 solute carrier family 35 member E1 2 2
MIRT532712 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT540807 SLC35F5 solute carrier family 35 member F5 2 2
MIRT563529 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT607723 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT608089 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT618519 SELPLG selectin P ligand 2 2
MIRT624702 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT624769 AKR1D1 aldo-keto reductase family 1 member D1 2 2
MIRT629974 MRPL36 mitochondrial ribosomal protein L36 2 2
MIRT631355 ZFP82 ZFP82 zinc finger protein 2 2
MIRT631425 CDNF cerebral dopamine neurotrophic factor 2 2
MIRT631664 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT631734 SF3B1 splicing factor 3b subunit 1 2 2
MIRT632333 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT632418 SLC30A5 solute carrier family 30 member 5 2 2
MIRT632530 PSMB2 proteasome subunit beta 2 2 2
MIRT633263 LDLR low density lipoprotein receptor 2 2
MIRT634326 SLC43A2 solute carrier family 43 member 2 2 2
MIRT634752 CRCP CGRP receptor component 2 2
MIRT635411 KIAA1614 KIAA1614 2 2
MIRT636280 RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase 2 2
MIRT636290 RAD51L3-RFFL RAD51L3-RFFL readthrough 2 2
MIRT641737 TXNL1 thioredoxin like 1 2 2
MIRT643527 ERAP2 endoplasmic reticulum aminopeptidase 2 2 2
MIRT643554 C11orf70 chromosome 11 open reading frame 70 2 2
MIRT647026 NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 2 2
MIRT647297 RBM43 RNA binding motif protein 43 2 2
MIRT648123 SEMA3E semaphorin 3E 2 4
MIRT648610 TPCN2 two pore segment channel 2 2 2
MIRT648716 IL10RB interleukin 10 receptor subunit beta 2 2
MIRT649424 CDC14B cell division cycle 14B 2 2
MIRT650028 DSG3 desmoglein 3 2 2
MIRT650280 TAS2R5 taste 2 receptor member 5 2 2
MIRT654238 RNF115 ring finger protein 115 2 2
MIRT657031 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT658406 FAM212B family with sequence similarity 212 member B 2 2
MIRT661079 FFAR2 free fatty acid receptor 2 2 2
MIRT661528 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT661875 PDLIM5 PDZ and LIM domain 5 2 2
MIRT662099 ZNF419 zinc finger protein 419 2 2
MIRT663637 HM13 histocompatibility minor 13 2 2
MIRT663702 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663844 TRIM72 tripartite motif containing 72 2 2
MIRT664768 MESDC2 mesoderm development LRP chaperone 2 2
MIRT665480 VSTM4 V-set and transmembrane domain containing 4 2 2
MIRT666532 RNF157 ring finger protein 157 2 2
MIRT668106 GK5 glycerol kinase 5 (putative) 2 2
MIRT669741 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT671009 MOB4 MOB family member 4, phocein 2 2
MIRT671582 SPIRE2 spire type actin nucleation factor 2 2 2
MIRT673260 INO80 INO80 complex subunit 2 2
MIRT673532 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT674713 FAM73A mitoguardin 1 2 2
MIRT675204 ZNF554 zinc finger protein 554 2 2
MIRT676487 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT676704 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT676850 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT676854 RAB3B RAB3B, member RAS oncogene family 2 2
MIRT676914 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT676999 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT677187 PDE12 phosphodiesterase 12 2 2
MIRT677472 SLC7A11 solute carrier family 7 member 11 2 2
MIRT677561 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT677778 FKTN fukutin 2 2
MIRT677895 DCP1A decapping mRNA 1A 2 2
MIRT677995 GATC glutamyl-tRNA amidotransferase subunit C 2 2
MIRT678238 HMGB1 high mobility group box 1 2 4
MIRT678312 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT678436 PDE4C phosphodiesterase 4C 2 2
MIRT678479 RNF222 ring finger protein 222 2 2
MIRT678590 ZNF91 zinc finger protein 91 2 2
MIRT678862 SLC7A14 solute carrier family 7 member 14 2 2
MIRT679240 LRP10 LDL receptor related protein 10 2 2
MIRT679387 WDR92 WD repeat domain 92 2 2
MIRT679500 ZNF106 zinc finger protein 106 2 2
MIRT679580 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT679826 TMEM106B transmembrane protein 106B 2 2
MIRT679859 ZFP30 ZFP30 zinc finger protein 2 2
MIRT680472 C3 complement C3 2 2
MIRT683698 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT684267 PRPF4 pre-mRNA processing factor 4 2 2
MIRT689404 ZNF573 zinc finger protein 573 2 2
MIRT694756 ZNF843 zinc finger protein 843 2 2
MIRT695955 FANCM Fanconi anemia complementation group M 2 2
MIRT696365 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT700681 PPAP2B phospholipid phosphatase 3 2 2
MIRT701214 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT702195 LRRC58 leucine rich repeat containing 58 2 2
MIRT706799 RAI1 retinoic acid induced 1 2 2
MIRT711086 NEUROD2 neuronal differentiation 2 2 2
MIRT715997 RGS12 regulator of G protein signaling 12 2 2
MIRT716399 SEPT5 septin 5 2 2
MIRT718442 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT722159 ARHGAP40 Rho GTPase activating protein 40 2 2
MIRT724960 PTK6 protein tyrosine kinase 6 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4532 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4532 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant High Gallbladder Cancer cell line (GBC-SD, NOZ)
hsa-miR-4532 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4532 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4532 Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4532 Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4532 Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4532 Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer tissue
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4532 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4532 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (mitochondrial RNA)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-4532 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4532 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-4532 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4532 Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4532 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (OVSAHO)

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