miRTarBase - #MIRT619061


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pre-miRNA Information
pre-miRNA hsa-mir-1306   
Genomic Coordinates chr22: 20086058 - 20086142
Synonyms MIRN1306, hsa-mir-1306, MIR1306
Description Homo sapiens miR-1306 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-1306-5p
Sequence 15| CCACCUCCCCUGCAAACGUCCA |36
Evidence Not_experimental
Experiments
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM5858927 8 COSMIC
COSM8222405 15 COSMIC
COSM1032175 17 COSMIC
COSM122562 22 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1197492175 14 dbSNP
rs1245517093 17 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TTC4   
Synonyms CNS1
Description tetratricopeptide repeat domain 4
Transcript NM_004623   
Expression
Putative miRNA Targets on TTC4
3'UTR of TTC4
(miRNA target sites are highlighted)		 
>TTC4|NM_004623|3'UTR
   1 CTAAGCCAGGGCCCCTGGATCTCCTCCCTTACCCTCCTCTGCTGGGAACCTAGCACACCTGAATCAGCTGGACATACTGC
  81 TGGAGTCCAGTGCTTTCTTTCCGTCACCCTGGGGATAGTCCTTCCTGGCATCGTGGTGGGGGAGGAGCCTCTGGCTTCCC
 161 TAAACTGCAGCCTCTCTGGCTGGTCTTCACTTTCCTCAGTTGATATAAAACTCTGGGTCTTGGCCATGATGTCCTTGGAC
 241 TCCATCGCTAAAGGGACCATCTGCTGCAGTTACCACAGCAACTGACCTGAGCGGCACCCTGGTCTGTGGAGATGGACTCA
 321 GGATCCAGTGACATGATTCTGAACTTTTGTGGAGTTTGACACCTTAGAGAAGCTACCCCTCAAACTGCACATCTACACAC
 401 AAACAAACAATGCATAGGATTCCAAGGCTTTAAAGCTGAGAGACCCTGGCCTCAAGTTATTTCATGCGCACAGAGGGAAG
 481 CCATGTGGGGTTGCTGAAGATGCCTTGAGGTGAAATGGGGGCAGGAAAGCCACATCTTGCTCTGCATTTATAAAGACCGT
 561 ACAAACTCAGATCCTTGGTACCCCTAAAAAGATTGCCAATTTTCTTCATCTTTGCCATATGGAGGACTGTGACAGACTTT
 641 GGACAGTGGCCTCTTGAGTTCCTCTGCAGTTTTGACATTTAGGATTTTGTGTCTTTTAAACTGGAAAATCTTCTAGCATG
 721 TTGGGTTGTTACAGAGTATATTTTTGTCTGCAGCTGTTTGTTGCCCCATTCCTAAGAGGAGTTTATCCATCCTGACTTGT
 801 AGCTGTGTGACTTCTTGCAGTGCCCCCACCCCATCCCCCCGGGAGAGTGTACTTCCCTGCTCCCAATGCAGAGGGATATG
 881 CACAGGCATGAGCTGTCCTGCGTCTGACAGAAGCCTGAAGAGTCATGTGTGGTTGGCCTGTGCTCTTCCCTCTGCTGTGA
 961 GAACACATTTCCCACAGAGGAGCCGTTCCATGGAGCCGAGCTACAGCAGCTGGCCTGCAGCCACTGAGTGTCACAGCAAT
1041 GAGAGAGCAATGTTTGCTGTAGTAAGCAGTGAGATTTAGGGGTTGGTTGTTACTATAGCAGAGCTAATACATGAGTAAAC
1121 TGAAGCCAGCTGCTGTCCTTAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acCUGCA--AACGUCCCCUCCACc 5'
            |:| |  | |::||||||| | 
Target 5' ctGGCATCGTGGTGGGGGAGGAGc 3'
 125 - 148 130.00 -20.92
2 
miRNA  3' accugcaaacgucccCUCCACc 5'
                         |||||| 
Target 5' tgctgaagatgccttGAGGTGa 3'
 492 - 513 120.00 -9.10
3 
miRNA  3' accUGCAAAC-GUCCCCUCCACc 5'
             ||  | | | | |||| || 
Target 5' ggcACCCTGGTCTGTGGAGATGg 3'
 293 - 315 115.00 -11.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30523510 10 COSMIC
COSN20073994 11 COSMIC
COSN8862384 31 COSMIC
COSN30475358 33 COSMIC
COSN31486838 37 COSMIC
COSN30534835 66 COSMIC
COSN23014393 107 COSMIC
COSN20600401 201 COSMIC
COSN20094847 408 COSMIC
COSN1105977 508 COSMIC
COSN20094848 641 COSMIC
COSN20851530 941 COSMIC
COSN23018512 1068 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs372795381 11 dbSNP
rs1264431704 13 dbSNP
rs927345070 15 dbSNP
rs1323884186 16 dbSNP
rs781029282 18 dbSNP
rs745364705 19 dbSNP
rs755741954 20 dbSNP
rs779722787 22 dbSNP
rs764887122 27 dbSNP
rs372383383 28 dbSNP
rs774154563 29 dbSNP
rs747931957 30 dbSNP
rs41297863 31 dbSNP
rs1470427940 33 dbSNP
rs1471511469 34 dbSNP
rs1175897596 36 dbSNP
rs200376441 37 dbSNP
rs1037954428 38 dbSNP
rs760735709 39 dbSNP
rs766375868 40 dbSNP
rs776701548 42 dbSNP
rs760053092 46 dbSNP
rs536748609 54 dbSNP
rs561140330 59 dbSNP
rs1270019996 62 dbSNP
rs1480552386 77 dbSNP
rs995842404 78 dbSNP
rs916256634 84 dbSNP
rs1357624749 88 dbSNP
rs1409089729 103 dbSNP
rs763631171 104 dbSNP
rs890137117 106 dbSNP
rs948308486 108 dbSNP
rs1338842095 112 dbSNP
rs1008571121 115 dbSNP
rs376699364 117 dbSNP
rs1330953532 124 dbSNP
rs1389853636 127 dbSNP
rs1411634603 133 dbSNP
rs1397078740 134 dbSNP
rs1044376967 139 dbSNP
rs1030713716 141 dbSNP
rs1188299939 142 dbSNP
rs1472252772 143 dbSNP
rs956524654 148 dbSNP
rs1304723237 151 dbSNP
rs1052638716 157 dbSNP
rs1257919988 168 dbSNP
rs901912591 175 dbSNP
rs1337315287 183 dbSNP
rs1367748397 185 dbSNP
rs1274190261 187 dbSNP
rs998030081 188 dbSNP
rs1354475983 189 dbSNP
rs530019461 190 dbSNP
rs1442963364 191 dbSNP
rs1336294071 197 dbSNP
rs1022201826 200 dbSNP
rs889127675 207 dbSNP
rs1006776673 209 dbSNP
rs1165350302 212 dbSNP
rs1016811216 217 dbSNP
rs1411127109 227 dbSNP
rs962644539 227 dbSNP
rs546229754 228 dbSNP
rs980732954 229 dbSNP
rs1177384282 234 dbSNP
rs1450945497 235 dbSNP
rs1254067234 244 dbSNP
rs1025461291 247 dbSNP
rs1450110695 248 dbSNP
rs960469572 262 dbSNP
rs1350133873 267 dbSNP
rs927251517 282 dbSNP
rs1062701 288 dbSNP
rs960036701 293 dbSNP
rs1237931084 294 dbSNP
rs1373053562 296 dbSNP
rs992873273 301 dbSNP
rs1435428886 311 dbSNP
rs1347767974 320 dbSNP
rs1319803849 336 dbSNP
rs907997662 339 dbSNP
rs566506848 348 dbSNP
rs77941984 349 dbSNP
rs17131750 353 dbSNP
rs569086027 355 dbSNP
rs1156277156 367 dbSNP
rs796389755 368 dbSNP
rs1455994202 376 dbSNP
rs534290857 392 dbSNP
rs187324691 395 dbSNP
rs1190997772 399 dbSNP
rs34946952 399 dbSNP
rs1204044756 403 dbSNP
rs935596044 416 dbSNP
rs945 450 dbSNP
rs1050647135 461 dbSNP
rs554756460 465 dbSNP
rs951 468 dbSNP
rs754258939 469 dbSNP
rs1213062145 478 dbSNP
rs948 479 dbSNP
rs1349987149 484 dbSNP
rs1052584942 485 dbSNP
rs1008517297 489 dbSNP
rs1052130302 503 dbSNP
rs933390606 504 dbSNP
rs947 518 dbSNP
rs892241780 531 dbSNP
rs946 538 dbSNP
rs1010722530 547 dbSNP
rs889085716 549 dbSNP
rs191174302 559 dbSNP
rs949 560 dbSNP
rs1442680474 563 dbSNP
rs950 568 dbSNP
rs13046 569 dbSNP
rs748373961 579 dbSNP
rs898406004 582 dbSNP
rs994069337 594 dbSNP
rs1034937527 596 dbSNP
rs150157001 600 dbSNP
rs1187439748 619 dbSNP
rs758444378 620 dbSNP
rs1477635854 625 dbSNP
rs1261239150 628 dbSNP
rs960837510 629 dbSNP
rs1394519820 637 dbSNP
rs35173267 638 dbSNP
rs397864157 638 dbSNP
rs377397102 639 dbSNP
rs1023801623 643 dbSNP
rs1310340746 655 dbSNP
rs992861941 659 dbSNP
rs1218967088 669 dbSNP
rs969199459 682 dbSNP
rs1275843907 685 dbSNP
rs979079385 697 dbSNP
rs1329613801 699 dbSNP
rs1465019585 701 dbSNP
rs1356747029 715 dbSNP
rs1014996493 716 dbSNP
rs1465376094 724 dbSNP
rs1421762455 725 dbSNP
rs962461132 731 dbSNP
rs41297865 733 dbSNP
rs1317731094 736 dbSNP
rs1360643853 738 dbSNP
rs1234481137 756 dbSNP
rs1199046820 757 dbSNP
rs1317146507 760 dbSNP
rs546304854 765 dbSNP
rs1234802726 766 dbSNP
rs138614051 769 dbSNP
rs1311428636 770 dbSNP
rs1481406008 776 dbSNP
rs986356773 781 dbSNP
rs1376183037 783 dbSNP
rs1195933751 785 dbSNP
rs1446687507 789 dbSNP
rs36036202 797 dbSNP
rs879684752 797 dbSNP
rs986304041 797 dbSNP
rs11803547 798 dbSNP
rs11803548 799 dbSNP
rs573209457 808 dbSNP
rs1037648194 809 dbSNP
rs1385726381 811 dbSNP
rs897848471 818 dbSNP
rs765604273 823 dbSNP
rs929867689 824 dbSNP
rs1052076694 826 dbSNP
rs1457246475 830 dbSNP
rs35707547 835 dbSNP
rs149294525 841 dbSNP
rs1168057117 842 dbSNP
rs529941118 853 dbSNP
rs1013828852 856 dbSNP
rs1318269404 863 dbSNP
rs1023497403 866 dbSNP
rs904920523 867 dbSNP
rs1375284739 868 dbSNP
rs1328379168 870 dbSNP
rs1387651859 875 dbSNP
rs1390297750 879 dbSNP
rs1168611714 881 dbSNP
rs756489628 885 dbSNP
rs1401627952 889 dbSNP
rs1381053189 893 dbSNP
rs1158092745 895 dbSNP
rs1439045819 896 dbSNP
rs546911808 901 dbSNP
rs559874729 902 dbSNP
rs1195280097 903 dbSNP
rs1031980968 906 dbSNP
rs1450480383 909 dbSNP
rs1266402290 913 dbSNP
rs956367069 916 dbSNP
rs1486628626 919 dbSNP
rs1339282538 925 dbSNP
rs532160978 927 dbSNP
rs1215207181 935 dbSNP
rs1352171722 938 dbSNP
rs1306190211 941 dbSNP
rs1384090107 951 dbSNP
rs946432083 961 dbSNP
rs1330947780 968 dbSNP
rs1299615852 969 dbSNP
rs1384176446 973 dbSNP
rs1361369444 980 dbSNP
rs769575194 981 dbSNP
rs146616469 983 dbSNP
rs904985988 985 dbSNP
rs955018965 992 dbSNP
rs182864818 993 dbSNP
rs1174314587 996 dbSNP
rs187461226 998 dbSNP
rs193271976 999 dbSNP
rs1320821985 1001 dbSNP
rs1263390641 1002 dbSNP
rs910747575 1005 dbSNP
rs1487062335 1013 dbSNP
rs1281830789 1017 dbSNP
rs12086065 1019 dbSNP
rs757675304 1020 dbSNP
rs1254660125 1029 dbSNP
rs919227407 1031 dbSNP
rs1015314515 1034 dbSNP
rs1277728390 1041 dbSNP
rs962081215 1044 dbSNP
rs973861165 1054 dbSNP
rs773944560 1056 dbSNP
rs1357513415 1060 dbSNP
rs1057165567 1070 dbSNP
rs896377712 1075 dbSNP
rs1263552930 1076 dbSNP
rs975977132 1078 dbSNP
rs1428856257 1082 dbSNP
rs1424070386 1083 dbSNP
rs1476625173 1084 dbSNP
rs1171427217 1088 dbSNP
rs1428784872 1090 dbSNP
rs139115973 1096 dbSNP
rs1178669083 1097 dbSNP
rs905039688 1099 dbSNP
rs1407541053 1101 dbSNP
rs1453647547 1103 dbSNP
rs1187590643 1106 dbSNP
rs1245578135 1111 dbSNP
rs1134128 1114 dbSNP
rs1364561299 1121 dbSNP
rs1383078512 1133 dbSNP
rs1300174374 1134 dbSNP
rs1032095319 1139 dbSNP
rs76069442 1145 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084040. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep1 HITS-CLIP data was present in GSM1084043. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep2 HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084040
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep1
Location of target site ENST00000371281.3 | 3UTR | GGCGGAGGUGGGUGGAUCACCUGAGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084043
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep2
Location of target site ENST00000371281.3 | 3UTR | AGGCGGAGGUGGGUGGAUCACCUGAGGUCAGGAGUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000371281.3 | 3UTR | GGAGGUGGGUGGAUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000371281.3 | 3UTR | AGGCGGAGGUGGGUGGAUCACCUGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1084073
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_AbnovaAb
Location of target site ENST00000371281.3 | 3UTR | GACACUUUGGGAGGCGGAGGUGGGUGGAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000371281.3 | 3UTR | AGGCGGAGGUGGGUGGAUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
184 hsa-miR-1306-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT089458 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT167143 LHFPL2 LHFPL tetraspan subfamily member 2 2 2
MIRT290873 BCL10 B-cell CLL/lymphoma 10 2 2
MIRT320237 CYCS cytochrome c, somatic 2 2
MIRT462980 ZNF784 zinc finger protein 784 2 2
MIRT478039 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT479102 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 4
MIRT482763 TMEM126B transmembrane protein 126B 2 2
MIRT489972 MCC mutated in colorectal cancers 2 4
MIRT495484 TNFAIP2 TNF alpha induced protein 2 2 2
MIRT496148 GPS1 G protein pathway suppressor 1 2 2
MIRT523370 GSR glutathione-disulfide reductase 2 2
MIRT526299 SORCS2 sortilin related VPS10 domain containing receptor 2 2 4
MIRT527427 NRL neural retina leucine zipper 2 2
MIRT527860 SMOC1 SPARC related modular calcium binding 1 2 6
MIRT529685 FBXL19 F-box and leucine rich repeat protein 19 2 2
MIRT531526 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT532461 PLGRKT plasminogen receptor with a C-terminal lysine 2 2
MIRT532519 KCNN1 potassium calcium-activated channel subfamily N member 1 2 2
MIRT532668 APOBEC3D apolipoprotein B mRNA editing enzyme catalytic subunit 3D 2 2
MIRT532718 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT533205 WAPAL WAPL cohesin release factor 2 2
MIRT536480 KIAA1549 KIAA1549 2 2
MIRT537158 GID8 GID complex subunit 8 homolog 2 2
MIRT539307 AKIRIN1 akirin 1 2 2
MIRT539569 CNKSR3 CNKSR family member 3 2 4
MIRT540045 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT540235 SAMD5 sterile alpha motif domain containing 5 2 2
MIRT543016 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT551436 F2 coagulation factor II, thrombin 2 2
MIRT556146 MED12L mediator complex subunit 12 like 2 2
MIRT570714 DGKE diacylglycerol kinase epsilon 2 2
MIRT572037 GRWD1 glutamate rich WD repeat containing 1 2 2
MIRT572409 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT572660 AGMAT agmatinase 2 4
MIRT611450 NRIP3 nuclear receptor interacting protein 3 2 2
MIRT611601 JAKMIP3 Janus kinase and microtubule interacting protein 3 2 4
MIRT612208 TMEM109 transmembrane protein 109 2 2
MIRT612312 VSIG10 V-set and immunoglobulin domain containing 10 2 2
MIRT614146 MAFK MAF bZIP transcription factor K 2 2
MIRT617371 C21orf62 chromosome 21 open reading frame 62 2 2
MIRT617689 MAPKBP1 mitogen-activated protein kinase binding protein 1 2 2
MIRT618495 DENND5B DENN domain containing 5B 2 4
MIRT618802 SPATA21 spermatogenesis associated 21 2 2
MIRT619061 TTC4 tetratricopeptide repeat domain 4 2 2
MIRT619902 NPTXR neuronal pentraxin receptor 2 2
MIRT620080 DZIP1L DAZ interacting zinc finger protein 1 like 2 2
MIRT622233 SLC25A45 solute carrier family 25 member 45 2 2
MIRT625262 ZNF566 zinc finger protein 566 2 2
MIRT625725 CXorf38 chromosome X open reading frame 38 2 2
MIRT625813 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT625839 NXPE2 neurexophilin and PC-esterase domain family member 2 2 2
MIRT626024 XRCC2 X-ray repair cross complementing 2 2 2
MIRT626054 PDE4C phosphodiesterase 4C 2 2
MIRT626082 CWF19L1 CWF19 like 1, cell cycle control (S. pombe) 2 2
MIRT626356 PACS1 phosphofurin acidic cluster sorting protein 1 2 2
MIRT626790 KCNK6 potassium two pore domain channel subfamily K member 6 2 2
MIRT627797 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT628234 FAM212B family with sequence similarity 212 member B 2 2
MIRT628241 FADS1 fatty acid desaturase 1 2 2
MIRT628249 ETF1 eukaryotic translation termination factor 1 2 2
MIRT628799 A2ML1 alpha-2-macroglobulin like 1 2 2
MIRT628879 FAM177A1 family with sequence similarity 177 member A1 2 4
MIRT629333 ZNF487P zinc finger protein 487 1 1
MIRT629435 RPL34 ribosomal protein L34 2 2
MIRT629977 MRPL36 mitochondrial ribosomal protein L36 2 2
MIRT630727 FPR1 formyl peptide receptor 1 2 2
MIRT630776 MSANTD3 Myb/SANT DNA binding domain containing 3 2 2
MIRT631074 ZNF829 zinc finger protein 829 2 2
MIRT633139 C6orf132 chromosome 6 open reading frame 132 2 2
MIRT633178 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT633510 RNF14 ring finger protein 14 2 2
MIRT633613 APCDD1 APC down-regulated 1 2 2
MIRT633668 MYO1F myosin IF 2 2
MIRT633707 LRRC8B leucine rich repeat containing 8 VRAC subunit B 2 2
MIRT633798 SOX7 SRY-box 7 2 2
MIRT634203 TMOD2 tropomodulin 2 2 4
MIRT634297 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT634509 NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2 2
MIRT634518 NKAP NFKB activating protein 2 2
MIRT634754 CRCP CGRP receptor component 2 2
MIRT635741 IFNAR1 interferon alpha and beta receptor subunit 1 2 2
MIRT636480 KLHL7 kelch like family member 7 2 2
MIRT637042 FITM2 fat storage inducing transmembrane protein 2 2 2
MIRT637748 POLR3K RNA polymerase III subunit K 2 2
MIRT638568 IFNE interferon epsilon 2 2
MIRT639155 TMEM167A transmembrane protein 167A 2 2
MIRT639848 ZBTB20 zinc finger and BTB domain containing 20 2 2
MIRT641770 ZNF207 zinc finger protein 207 2 2
MIRT642285 ZNF99 zinc finger protein 99 2 2
MIRT642685 KRT74 keratin 74 2 2
MIRT643530 ERAP2 endoplasmic reticulum aminopeptidase 2 2 2
MIRT643742 ZNF284 zinc finger protein 284 2 4
MIRT643945 WIPF3 WAS/WASL interacting protein family member 3 2 2
MIRT644320 NFKBID NFKB inhibitor delta 2 2
MIRT644383 ZNF286A zinc finger protein 286A 2 2
MIRT645130 HES2 hes family bHLH transcription factor 2 2 2
MIRT645607 PCDH11X protocadherin 11 X-linked 2 2
MIRT647121 ZNF446 zinc finger protein 446 2 2
MIRT648484 CMBL carboxymethylenebutenolidase homolog 2 2
MIRT648549 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT649252 TRIM65 tripartite motif containing 65 2 2
MIRT649468 SLC10A7 solute carrier family 10 member 7 2 2
MIRT650013 KLB klotho beta 2 2
MIRT650068 CCDC134 coiled-coil domain containing 134 2 2
MIRT650325 RTN2 reticulon 2 2 2
MIRT651093 ZNF516 zinc finger protein 516 2 2
MIRT651265 ZKSCAN4 zinc finger with KRAB and SCAN domains 4 2 2
MIRT651272 ZKSCAN1 zinc finger with KRAB and SCAN domains 1 2 2
MIRT651402 ZBTB16 zinc finger and BTB domain containing 16 2 2
MIRT652163 TRIM66 tripartite motif containing 66 2 2
MIRT653153 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 2 2
MIRT653477 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT653922 SERPINC1 serpin family C member 1 2 2
MIRT654243 RNF115 ring finger protein 115 2 2
MIRT655354 PCDH11Y protocadherin 11 Y-linked 2 2
MIRT655958 NDST1 N-deacetylase and N-sulfotransferase 1 2 2
MIRT656318 MESDC1 talin rod domain containing 1 2 2
MIRT656578 LSM10 LSM10, U7 small nuclear RNA associated 2 2
MIRT657210 IKZF2 IKAROS family zinc finger 2 2 2
MIRT657856 GJB1 gap junction protein beta 1 2 2
MIRT658207 FBXO44 F-box protein 44 2 2
MIRT659003 DIAPH1 diaphanous related formin 1 2 2
MIRT659349 CSRP1 cysteine and glycine rich protein 1 2 2
MIRT659501 CISD3 CDGSH iron sulfur domain 3 2 2
MIRT659761 CCDC171 coiled-coil domain containing 171 2 2
MIRT660149 BRD4 bromodomain containing 4 2 2
MIRT661582 EPHX2 epoxide hydrolase 2 2 2
MIRT661753 ATM ATM serine/threonine kinase 2 2
MIRT662223 CCRL2 C-C motif chemokine receptor like 2 2 2
MIRT663883 CXorf56 chromosome X open reading frame 56 2 2
MIRT664308 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT664649 GALM galactose mutarotase 2 2
MIRT664671 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 2
MIRT665050 C3 complement C3 2 2
MIRT666467 SCRG1 stimulator of chondrogenesis 1 2 2
MIRT666529 RNF170 ring finger protein 170 2 2
MIRT669118 CDC42BPG CDC42 binding protein kinase gamma 2 2
MIRT669311 C17orf75 chromosome 17 open reading frame 75 2 2
MIRT669358 BHLHE22 basic helix-loop-helix family member e22 2 2
MIRT669691 ABLIM1 actin binding LIM protein 1 2 2
MIRT674223 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT674766 QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 2 2
MIRT675207 ZNF554 zinc finger protein 554 2 2
MIRT675271 ZNF431 zinc finger protein 431 2 2
MIRT676265 PBOV1 prostate and breast cancer overexpressed 1 2 2
MIRT676573 VSIG1 V-set and immunoglobulin domain containing 1 2 2
MIRT677566 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT677631 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2 2
MIRT678115 MICA MHC class I polypeptide-related sequence A 2 2
MIRT678694 RNF157 ring finger protein 157 2 2
MIRT679583 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT679621 MED28 mediator complex subunit 28 2 2
MIRT683700 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT683721 LACTB lactamase beta 2 2
MIRT690967 APOL1 apolipoprotein L1 2 2
MIRT691611 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT702524 KCND3 potassium voltage-gated channel subfamily D member 3 2 2
MIRT704762 CDKN2AIPNL CDKN2A interacting protein N-terminal like 2 2
MIRT708738 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT708898 SKIDA1 SKI/DACH domain containing 1 2 2
MIRT709965 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT710373 GM2A GM2 ganglioside activator 2 2
MIRT710533 TMEM201 transmembrane protein 201 2 2
MIRT710582 HLCS holocarboxylase synthetase 2 2
MIRT711030 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT712200 SHROOM4 shroom family member 4 2 2
MIRT713798 CPLX2 complexin 2 2 2
MIRT714096 ZNF486 zinc finger protein 486 2 2
MIRT714923 PPP1R12C protein phosphatase 1 regulatory subunit 12C 2 2
MIRT716518 TNPO2 transportin 2 2 2
MIRT716701 HLA-B major histocompatibility complex, class I, B 2 2
MIRT717070 MTMR6 myotubularin related protein 6 2 2
MIRT719561 CBL Cbl proto-oncogene 2 2
MIRT719688 ALDH1L2 aldehyde dehydrogenase 1 family member L2 2 2
MIRT720134 RIMKLA ribosomal modification protein rimK like family member A 2 2
MIRT720222 IPPK inositol-pentakisphosphate 2-kinase 2 2
MIRT720982 METTL21A methyltransferase like 21A 2 2
MIRT723821 PDS5A PDS5 cohesin associated factor A 2 2
MIRT723999 LMTK2 lemur tyrosine kinase 2 2 2
MIRT724963 PTK6 protein tyrosine kinase 6 2 2
MIRT725217 PEA15 phosphoprotein enriched in astrocytes 15 2 2
MIRT725262 PARVB parvin beta 2 2
MIRT755883 METTL14 methyltransferase like 14 3 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-1306 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-mir-1306 Fluorouracil 3385 NSC19893 approved resistant cell line (KYSE)
hsa-miR-1306-5p Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia tissue
hsa-miR-1306-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (HS578T)
hsa-miR-1306-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-1306-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-1306-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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