miRTarBase - #MIRT619362


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pre-miRNA Information
pre-miRNA hsa-mir-3120   
Genomic Coordinates chr1: 172138808 - 172138888
Description Homo sapiens miR-3120 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3120-5p
Sequence 13| CCUGUCUGUGCCUGCUGUACA |33
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 19 1 + 172138838 26449202, 27587585 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN26637643 8 COSMIC
COSN31603497 11 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs750386761 8 dbSNP
rs760725207 9 dbSNP
rs766486759 10 dbSNP
rs754055278 12 dbSNP
rs755288536 19 dbSNP
rs754726014 21 dbSNP
Putative Targets

Gene Information
Gene Symbol CFHR5   
Synonyms CFHL5, CFHR5D, FHR-5, FHR5
Description complement factor H related 5
Transcript NM_030787   
Expression
Putative miRNA Targets on CFHR5
3'UTR of CFHR5
(miRNA target sites are highlighted)		 
>CFHR5|NM_030787|3'UTR
   1 AGCAAGCATAATTTTCCTGAATATATTCTTCAAACATCCATCTATGCTAAAAGTAGCCATTATGTAGCCAATTCTGTAGT
  81 TACTTCTTTTATTCTTTCAGGTGTTGTTTAACTCAGTTTTATTTAGAACTCTGGATTTTTAGAGCTTTAGAAATTTGTAA
 161 GCTGAGAGAACAATGTTTCACTTAATAGGAGGGTGTCTTAGTCCATATTACATTGTTATAACAGAGTATCACAGACTGGA
 241 TAACTTCTAACCAATAGTTTATTTGTTTCATAAATCTAAAAGCTGAGAAGTCCAAGATGGTGGGGCTGCCTCTGGTGAGG
 321 GTCTTCTCGAAGCATCATAATATGCTGGAAGGCATCACAACATGGTGGAAGGGATCACGTGGCAAAAGAGCATGTACATG
 401 GGAGTGAGAGAAAAAGAGAGAGAGAGACAGAGTGGCGGGGGCGGGGAGGAGCGCAAACTCATCCTTTATAAAGACACCAC
 481 TCCTGAGATAACAATCCAATCCCATGATAATGACATTAATCCATTCAAGAAGATAGAGCTCTCGTGACTTAATCACCTTC
 561 TAAAGATCTCACCTGACAACACTGTTGCATTGGCAGTTAAGTTTCCACGTAAACTTTCGGGGACACATTCAAACCACAGG
 641 AGAAACTCAAATTGTTCCTGGGCAAATCACAACATGGGGAATTTTATTCATAAATGTCCACAGAAACAGTAAATGTTCTC
 721 GCTTCAGTACTTAATTCATCTAATCCCTCCTGTTTGTCTCAAATTATAGGATAACTTTGAAACTTTCTGAATTAACGTTA
 801 TTTAAAAGGAAATGTAGATGTTATTTTAGTCTCTATCTTCATGTTATTATCACTTAAAAACCTGCGAAAGCTGTCAACTT
 881 TTGTGGTTGTAGCAAGTATTAATAAATATTTATAAATCCTCTAATGTAAGTCTAGCTACCTATCCAATACTAAATACCCC
 961 TTAAAGTATTAAATGCACTATCTGCTGTAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acAUGUCGUC-C---GUGUCUGUCc 5'
            ||:| ||| |   ||||||| | 
Target 5' gtTATAACAGAGTATCACAGACTGg 3'
 215 - 239 131.00 -18.30
2 
miRNA  3' acaUGUCGUCCGUGUCUGUCc 5'
             | || ||  | |||||| 
Target 5' aaaAGAG-AGAGAGAGACAGa 3'
 412 - 431 121.00 -9.10
3 
miRNA  3' acaugucguccGUGUC--UGUCc 5'
                     |||||  |||| 
Target 5' tcataaatgtcCACAGAAACAGt 3'
 688 - 710 110.00 -9.72
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
294553 238 ClinVar
294554 325 ClinVar
294555 363 ClinVar
294556 398 ClinVar
294557 415 ClinVar
294558 503 ClinVar
873697 519 ClinVar
294559 620 ClinVar
873698 655 ClinVar
294560 742 ClinVar
294561 746 ClinVar
294562 803 ClinVar
873699 861 ClinVar
294563 867 ClinVar
874669 931 ClinVar
294564 967 ClinVar
874670 970 ClinVar
874671 975 ClinVar
COSN31612381 3 COSMIC
COSN30114517 11 COSMIC
COSN30507696 13 COSMIC
COSN31571781 16 COSMIC
COSN30474692 17 COSMIC
COSN30470915 39 COSMIC
COSN31512117 40 COSMIC
COSN507571 53 COSMIC
COSN30498463 56 COSMIC
COSN30513743 59 COSMIC
COSN30513745 60 COSMIC
COSN8416992 63 COSMIC
COSN2531019 68 COSMIC
COSN31590112 78 COSMIC
COSN30141301 99 COSMIC
COSN30537708 172 COSMIC
COSN31525260 225 COSMIC
COSN9056000 238 COSMIC
COSN17076075 401 COSMIC
COSN8968748 597 COSMIC
COSN26748364 609 COSMIC
COSN28201891 724 COSMIC
COSN28198037 788 COSMIC
COSN6436362 803 COSMIC
COSN27763057 867 COSMIC
COSN25220358 881 COSMIC
rs10922153 803 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs773828786 1 dbSNP
rs761491916 4 dbSNP
rs767151038 8 dbSNP
rs750843342 11 dbSNP
rs1452510442 18 dbSNP
rs1246954022 19 dbSNP
rs1160195549 20 dbSNP
rs760954453 21 dbSNP
rs1453300574 25 dbSNP
rs747312519 40 dbSNP
rs199554431 41 dbSNP
rs369204442 42 dbSNP
rs371795291 43 dbSNP
rs779177613 48 dbSNP
rs752824001 49 dbSNP
rs769122811 50 dbSNP
rs747186769 51 dbSNP
rs769505570 53 dbSNP
rs1382199019 57 dbSNP
rs1295801219 58 dbSNP
rs1462485128 59 dbSNP
rs545416040 60 dbSNP
rs1013440451 64 dbSNP
rs1306027817 64 dbSNP
rs887965185 71 dbSNP
rs1192808438 75 dbSNP
rs1426780698 79 dbSNP
rs948882659 87 dbSNP
rs1211551509 96 dbSNP
rs1285142657 108 dbSNP
rs969338181 110 dbSNP
rs1365361182 113 dbSNP
rs1044682796 116 dbSNP
rs563764666 127 dbSNP
rs984822384 128 dbSNP
rs1277982992 130 dbSNP
rs1308367847 139 dbSNP
rs1226328191 143 dbSNP
rs1324163438 147 dbSNP
rs1302787624 150 dbSNP
rs1015968854 160 dbSNP
rs1370951971 162 dbSNP
rs1324246560 163 dbSNP
rs1467491884 169 dbSNP
rs907442446 176 dbSNP
rs1167551435 181 dbSNP
rs1207518441 192 dbSNP
rs1379383254 195 dbSNP
rs1194341723 197 dbSNP
rs962090799 198 dbSNP
rs1252319004 206 dbSNP
rs1439304308 207 dbSNP
rs1273525600 211 dbSNP
rs1272993767 217 dbSNP
rs1003086533 223 dbSNP
rs559647040 224 dbSNP
rs1337050555 225 dbSNP
rs1257205875 234 dbSNP
rs886045752 238 dbSNP
rs1223630614 239 dbSNP
rs918739168 249 dbSNP
rs1034691277 256 dbSNP
rs986978596 264 dbSNP
rs1336712481 275 dbSNP
rs892107286 278 dbSNP
rs1009337730 282 dbSNP
rs1328617352 284 dbSNP
rs1022032664 291 dbSNP
rs1477294207 295 dbSNP
rs776710591 297 dbSNP
rs942968411 298 dbSNP
rs1044115042 307 dbSNP
rs1393388087 311 dbSNP
rs967934524 318 dbSNP
rs886045753 325 dbSNP
rs1429972804 329 dbSNP
rs1166311598 334 dbSNP
rs903888691 338 dbSNP
rs1471129352 340 dbSNP
rs1369507765 356 dbSNP
rs1233180727 357 dbSNP
rs886045754 363 dbSNP
rs1304664449 377 dbSNP
rs1435667409 378 dbSNP
rs1259152266 384 dbSNP
rs115744316 398 dbSNP
rs1277645719 399 dbSNP
rs1242874906 400 dbSNP
rs1352036126 405 dbSNP
rs769938869 408 dbSNP
rs1435666999 413 dbSNP
rs1052496617 415 dbSNP
rs886045755 415 dbSNP
rs896595622 415 dbSNP
rs1313676001 417 dbSNP
rs1013345783 419 dbSNP
rs148256048 423 dbSNP
rs905103957 425 dbSNP
rs1402336868 430 dbSNP
rs975991539 432 dbSNP
rs1006169245 437 dbSNP
rs562239793 437 dbSNP
rs919273259 441 dbSNP
rs542330909 443 dbSNP
rs1190659978 444 dbSNP
rs1016329170 445 dbSNP
rs909165793 448 dbSNP
rs942042572 451 dbSNP
rs866374508 453 dbSNP
rs1450465022 454 dbSNP
rs866880802 464 dbSNP
rs1221434096 468 dbSNP
rs909289048 474 dbSNP
rs1390906997 486 dbSNP
rs1337395644 493 dbSNP
rs1030056435 497 dbSNP
rs948949776 498 dbSNP
rs1044959777 500 dbSNP
rs561492578 503 dbSNP
rs1186081901 504 dbSNP
rs1389177753 505 dbSNP
rs907333012 507 dbSNP
rs1353836063 509 dbSNP
rs1280122837 516 dbSNP
rs938943284 527 dbSNP
rs1053338748 540 dbSNP
rs1164846795 544 dbSNP
rs892159687 545 dbSNP
rs1317553783 560 dbSNP
rs1404739449 561 dbSNP
rs954452383 563 dbSNP
rs529500424 573 dbSNP
rs1165385575 577 dbSNP
rs1474652746 582 dbSNP
rs745408180 584 dbSNP
rs1318916053 587 dbSNP
rs1346853484 591 dbSNP
rs1437370647 594 dbSNP
rs1475437040 598 dbSNP
rs541811310 606 dbSNP
rs1009223187 609 dbSNP
rs1214253536 610 dbSNP
rs1470227887 619 dbSNP
rs550863021 620 dbSNP
rs1364810357 621 dbSNP
rs1246987507 631 dbSNP
rs986927719 651 dbSNP
rs1215448610 658 dbSNP
rs1354662703 659 dbSNP
rs903596144 662 dbSNP
rs1228061784 668 dbSNP
rs942938695 674 dbSNP
rs1007272466 680 dbSNP
rs1373138355 681 dbSNP
rs979739045 697 dbSNP
rs773449247 702 dbSNP
rs1392067948 721 dbSNP
rs1017863735 722 dbSNP
rs925258037 727 dbSNP
rs1410236364 728 dbSNP
rs965877685 735 dbSNP
rs975990195 736 dbSNP
rs117389812 742 dbSNP
rs886045756 746 dbSNP
rs1254154686 751 dbSNP
rs984749764 752 dbSNP
rs1467414838 757 dbSNP
rs1235019651 762 dbSNP
rs1461520226 764 dbSNP
rs1052401907 767 dbSNP
rs909339861 770 dbSNP
rs970553481 774 dbSNP
rs980180828 775 dbSNP
rs949507855 776 dbSNP
rs1158862629 781 dbSNP
rs1236610762 798 dbSNP
rs10922153 803 dbSNP
rs551890459 807 dbSNP
rs1304023985 810 dbSNP
rs938843083 814 dbSNP
rs905052166 816 dbSNP
rs1299678223 817 dbSNP
rs1442437453 818 dbSNP
rs575601631 820 dbSNP
rs1016157060 824 dbSNP
rs913477499 824 dbSNP
rs897759055 830 dbSNP
rs1395232794 834 dbSNP
rs945062453 836 dbSNP
rs993128688 838 dbSNP
rs775034377 850 dbSNP
rs566913870 853 dbSNP
rs1253017972 854 dbSNP
rs1178171309 856 dbSNP
rs1480401865 858 dbSNP
rs906120832 861 dbSNP
rs1336429482 866 dbSNP
rs534182452 867 dbSNP
rs1279775227 872 dbSNP
rs1233394254 881 dbSNP
rs903485927 898 dbSNP
rs1280448827 920 dbSNP
rs1030005683 928 dbSNP
rs1007735546 931 dbSNP
rs1352932699 933 dbSNP
rs1305792499 941 dbSNP
rs1227058326 942 dbSNP
rs1375461218 944 dbSNP
rs1311750335 947 dbSNP
rs1464948028 947 dbSNP
rs1366081086 952 dbSNP
rs1038758476 953 dbSNP
rs901700469 956 dbSNP
rs1406321839 958 dbSNP
rs1418828902 958 dbSNP
rs997293726 959 dbSNP
rs57315298 964 dbSNP
rs1190308650 966 dbSNP
rs886045757 967 dbSNP
rs1323649338 969 dbSNP
rs115075908 970 dbSNP
rs950635746 971 dbSNP
rs1486919656 985 dbSNP
rs568222338 994 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084068. RNA binding protein: AGO2. Condition:CLIP_noemetine_SigmaAb HITS-CLIP data was present in GSM1084072. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000367414.5 | 3UTR | GAGUGAGAGAAAAAGAGAGAGAGAGACAGAGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000367414.5 | 3UTR | ACAUGGGAGUGAGAGAAAAAGAGAGAGAGAGACA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084068
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SigmaAb
Location of target site ENST00000367414.5 | 3UTR | AAAAGAGAGAGAGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1084072
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_AbnovaAb
Location of target site ENST00000367414.5 | 3UTR | ACAUGGGAGUGAGAGAAAAAGAGAGAGAGAGACAGAGUGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1084073
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_AbnovaAb
Location of target site ENST00000367414.5 | 3UTR | GAGAGAAAAAGAGAGAGAGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000367414.5 | 3UTR | AAAAAGAGAGAGAGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
134 hsa-miR-3120-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT096972 BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 2 2
MIRT442624 LOX lysyl oxidase 2 2
MIRT473438 MDM4 MDM4, p53 regulator 2 2
MIRT490011 KIFC2 kinesin family member C2 2 2
MIRT496449 N6AMT1 N-6 adenine-specific DNA methyltransferase 1 2 2
MIRT496752 TGIF2 TGFB induced factor homeobox 2 2 2
MIRT497721 CYP1A1 cytochrome P450 family 1 subfamily A member 1 2 2
MIRT498287 PADI3 peptidyl arginine deiminase 3 2 2
MIRT503195 ACVR1B activin A receptor type 1B 2 4
MIRT504760 TEP1 telomerase associated protein 1 2 4
MIRT517810 UGDH UDP-glucose 6-dehydrogenase 2 6
MIRT519686 ZNF622 zinc finger protein 622 2 4
MIRT520263 URGCP upregulator of cell proliferation 2 2
MIRT523051 ICMT isoprenylcysteine carboxyl methyltransferase 2 2
MIRT525601 OLR1 oxidized low density lipoprotein receptor 1 2 4
MIRT526995 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT528699 TRAF3IP2 TRAF3 interacting protein 2 2 4
MIRT533142 WNT10A Wnt family member 10A 2 2
MIRT537618 ERI1 exoribonuclease 1 2 2
MIRT539707 EIF3H eukaryotic translation initiation factor 3 subunit H 2 2
MIRT539752 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT539808 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT539941 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT540424 FAM83F family with sequence similarity 83 member F 2 2
MIRT540509 CXCL10 C-X-C motif chemokine ligand 10 2 2
MIRT540720 GUF1 GUF1 homolog, GTPase 2 2
MIRT541630 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT542286 POLR3K RNA polymerase III subunit K 2 2
MIRT542456 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT542550 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT542771 PPAP2B phospholipid phosphatase 3 2 2
MIRT550085 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT551458 CARKD NAD(P)HX dehydratase 2 2
MIRT555622 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 2
MIRT569136 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT572328 HSPB6 heat shock protein family B (small) member 6 2 2
MIRT574607 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT575583 Mcm8 minichromosome maintenance 8 homologous recombination repair factor 2 4
MIRT576125 Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) 2 5
MIRT576657 Fam216a family with sequence similarity 216, member A 2 2
MIRT607222 ACSM2A acyl-CoA synthetase medium chain family member 2A 2 4
MIRT607292 CD300E CD300e molecule 2 6
MIRT607746 ANGPT4 angiopoietin 4 2 2
MIRT607905 SPRYD4 SPRY domain containing 4 2 2
MIRT608159 HRK harakiri, BCL2 interacting protein 2 7
MIRT608657 ABCF3 ATP binding cassette subfamily F member 3 2 4
MIRT609115 ZNF703 zinc finger protein 703 2 6
MIRT610231 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT610870 NUDCD3 NudC domain containing 3 2 2
MIRT611217 MC2R melanocortin 2 receptor 2 2
MIRT614858 PLEKHA6 pleckstrin homology domain containing A6 2 2
MIRT616966 LMX1A LIM homeobox transcription factor 1 alpha 2 2
MIRT617258 GLIPR1L2 GLI pathogenesis related 1 like 2 2 2
MIRT618009 SLC9A3R2 SLC9A3 regulator 2 2 2
MIRT619067 BSND barttin CLCNK type accessory beta subunit 2 4
MIRT619295 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT619348 GINM1 glycoprotein integral membrane 1 2 2
MIRT619362 CFHR5 complement factor H related 5 2 2
MIRT619541 PIWIL2 piwi like RNA-mediated gene silencing 2 2 2
MIRT619782 NRIP2 nuclear receptor interacting protein 2 2 2
MIRT619994 NPAP1 nuclear pore associated protein 1 2 2
MIRT621030 CDC14B cell division cycle 14B 2 2
MIRT622033 STAT5A signal transducer and activator of transcription 5A 2 2
MIRT622728 PITPNM3 PITPNM family member 3 2 2
MIRT623144 NAV2 neuron navigator 2 2 2
MIRT623600 IPO9 importin 9 2 2
MIRT624608 B3GALT5 beta-1,3-galactosyltransferase 5 2 2
MIRT624905 CTCFL CCCTC-binding factor like 2 2
MIRT625030 SPC24 SPC24, NDC80 kinetochore complex component 2 2
MIRT625688 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 5
MIRT626531 EMCN endomucin 2 2
MIRT627204 ZDHHC20 zinc finger DHHC-type containing 20 2 2
MIRT628033 LSAMP limbic system-associated membrane protein 2 2
MIRT628203 FREM2 FRAS1 related extracellular matrix protein 2 2 2
MIRT631012 LINS lines homolog 1 2 2
MIRT633195 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT633890 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT634023 MOB4 MOB family member 4, phocein 2 2
MIRT634416 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 2 2
MIRT636866 ARSE arylsulfatase E (chondrodysplasia punctata 1) 2 2
MIRT642527 ANKRD9 ankyrin repeat domain 9 2 2
MIRT645408 FAM110A family with sequence similarity 110 member A 2 2
MIRT645635 SYTL4 synaptotagmin like 4 2 2
MIRT646013 TNFAIP8L2 TNF alpha induced protein 8 like 2 2 2
MIRT646686 ASGR2 asialoglycoprotein receptor 2 2 2
MIRT652838 TACO1 translational activator of cytochrome c oxidase I 2 2
MIRT655156 PHF21B PHD finger protein 21B 2 2
MIRT658491 EXOC7 exocyst complex component 7 2 2
MIRT659398 CORO2A coronin 2A 2 2
MIRT666825 PRCP prolylcarboxypeptidase 2 2
MIRT666866 POU2F2 POU class 2 homeobox 2 2 2
MIRT668224 GABRA1 gamma-aminobutyric acid type A receptor alpha1 subunit 2 2
MIRT673288 PDE3A phosphodiesterase 3A 2 2
MIRT673878 KLF2 Kruppel like factor 2 2 2
MIRT681721 KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 2 2
MIRT682406 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT684109 MCM10 minichromosome maintenance 10 replication initiation factor 2 2
MIRT684423 TUFT1 tuftelin 1 2 2
MIRT684684 OR7D2 olfactory receptor family 7 subfamily D member 2 2 2
MIRT686638 TMEM184C transmembrane protein 184C 2 2
MIRT689457 NXN nucleoredoxin 2 2
MIRT689627 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT690773 PLA2G2C phospholipase A2 group IIC 2 2
MIRT690822 SGSM2 small G protein signaling modulator 2 2 2
MIRT693669 MXRA7 matrix remodeling associated 7 2 2
MIRT695553 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT695872 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT698160 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT699933 RUFY2 RUN and FYVE domain containing 2 2 2
MIRT708639 UBE2W ubiquitin conjugating enzyme E2 W 2 2
MIRT710816 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT711242 TRAT1 T-cell receptor associated transmembrane adaptor 1 2 2
MIRT711542 MSH3 mutS homolog 3 2 2
MIRT711749 DTX1 deltex E3 ubiquitin ligase 1 2 2
MIRT712303 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT712922 RPF2 ribosome production factor 2 homolog 2 2
MIRT714027 SYDE2 synapse defective Rho GTPase homolog 2 2 2
MIRT714768 TERF1 telomeric repeat binding factor 1 2 2
MIRT714844 ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 2 2
MIRT715223 NPVF neuropeptide VF precursor 2 2
MIRT716110 GMPS guanine monophosphate synthase 2 2
MIRT716174 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT716383 C6orf223 chromosome 6 open reading frame 223 2 2
MIRT716527 KSR2 kinase suppressor of ras 2 2 2
MIRT716962 P2RY6 pyrimidinergic receptor P2Y6 2 2
MIRT717605 DSTYK dual serine/threonine and tyrosine protein kinase 2 2
MIRT717696 PTGS1 prostaglandin-endoperoxide synthase 1 2 2
MIRT721360 ENTHD1 ENTH domain containing 1 2 2
MIRT721381 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT721935 RASSF2 Ras association domain family member 2 2 2
MIRT722094 SUSD1 sushi domain containing 1 2 2
MIRT722837 C17orf102 chromosome 17 open reading frame 102 2 2
MIRT722990 TOR1A torsin family 1 member A 2 2
MIRT724174 ABCF2 ATP binding cassette subfamily F member 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3120-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-3120-5p Prednisone/Azathioprine/Methotrexate/Cyclophosphamide/Mycophenolate mofetil sensitive tissue (myasthenia gravis)
hsa-miR-3120-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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