miRTarBase - #MIRT619741


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pre-miRNA Information
pre-miRNA hsa-mir-6819   
Genomic Coordinates chr22: 36286847 - 36286907
Description Homo sapiens miR-6819 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6819-3p
Sequence 41| AAGCCUCUGUCCCCACCCCAG |61
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1279530967 2 dbSNP
rs967579979 3 dbSNP
rs776891214 4 dbSNP
rs771166635 8 dbSNP
rs747037324 9 dbSNP
rs879248090 11 dbSNP
rs1485325191 12 dbSNP
rs778157316 16 dbSNP
Putative Targets

Gene Information
Gene Symbol SRFBP1   
Synonyms BUD22, P49, Rlb1, STRAP, p49/STRAP
Description serum response factor binding protein 1
Transcript NM_152546   
Expression
Putative miRNA Targets on SRFBP1
3'UTR of SRFBP1
(miRNA target sites are highlighted)		 
>SRFBP1|NM_152546|3'UTR
   1 TTAGTGCCTCTTTCTGCAAACTTTTCCATCTAAAAAAAAAAATGTTTTTTTTAAGACAGGATCTCATTCTGTTGCCCAGA
  81 CTAGAGTACAATATTGCAATCACAGCTCACTGCAGCCTCAAACTCCTGGGCTCAAGTGATCCTCCCACCTCTGCCTCCCA
 161 AAGGGCTGGGACTGCAGGTGCATGCACTACCATGCCCAGCTTTCTCACCCCAGGCTCTGCAGCTATTACTTAAACTCGTA
 241 TTTGAATAAGTCTCTTGGGGAGAATTATAGAATGTTTGTTTTTGTATTTTTTTTTAAAGTAAATTCAACTTACGCTTATA
 321 TAAGCCTTTCACAAATCCAATATGTACTTAAATTGATTTTTAATAATATCCCTCAGACTGTTTCCCTTATGAAGTAATTT
 401 GGGGATTTTAGTGATCTCATATTTTCTCTTTAGTGCTTATCATGAAATGTGCTTCACTGGTTCAGCTCTGTTGTTTCCTT
 481 AAACATAAATGTCAATATATATTTAAAATAATAATGGAAACATAGGAAATCAGCTATTTAAACCAGATCACCCTTGTTAA
 561 AAATCATTCTTGTTAGCAAACTAAAATAGTAACTTTTATTATGGATGTACAGATAAATATTAATTTTATTATAGTTTTAA
 641 GTACTTGTGATCATGTACTTTTTGATTCTAAAATAGTTGTCTAGGACAATTTTGGGATTCTTAATTATATTTTAGTTAAG
 721 AAAATTGTTTAAATATAGCAATACAACCAATAATTTGTTTTATGTTTCACTGCATATAAATATTTCCATTAAATCAAGAA
 801 TGTATATTATCTAGTTTTTACTATACTTATTTTAAAATTTTTGAGGAATCATAGATTCTAATTTTTAAGAACAAATTCTG
 881 AAGGTGGTAGGATTAAAAGAATATTTCCACTGATGGCTAAGCAAAGAAGTTGTAAGATGACTCACTGAGGAAGGGACTGC
 961 TTTATACATCACAGTACTGCTATTTAAAAGGAAAACAGAAATTTTTAAATCCCTTCAAATGTTTCACTTTTGCTATGCTG
1041 GGAAAAATTTTGAAGTTCTTGGTAAACTGAATAATGCTAATCCATGTTTCCTGCACATTAGTTCCTTTAATGGCAGGGAA
1121 GGCCATCTGGTTAACCTGTATTCACAAACTCTCAAGAGTTTCTACTTATTTCAGGAGCTTAAGAATTTAGATAACTCAGC
1201 CGGGCGTGGTGACTCATGCCTATAATCCCAGCACTTTGGGAGGCTGAGGCGGGTAGATCGCTAGAGGCAAGGAGTTCAAA
1281 ACCAGCCTGGGCAACATGGTGAAACCCTGTCTCTACTAAAAATACAGAAAATTATCCAGGCGTGGTGGCCGGCATCTGTA
1361 ATTCCAGCTACTCAGAAGGCTGAGGCATAAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATTGCACC
1441 ACTGCACTCCAGCCTGGGTGACAGAGTATGACTG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gacCCCACC--CCUGUCUCCGaa 5'
             |||| |   | :||||||  
Target 5' ggcGGGTAGATCGCTAGAGGCaa 3'
 1248 - 1270 132.00 -13.80
2 
miRNA  3' gaccccACCC-CUGUCUCCGAa 5'
                |||| |:::||||:| 
Target 5' tgaaccTGGGAGGTGGAGGTTg 3'
 1399 - 1420 127.00 -17.20
3 
miRNA  3' gaccccaccccugUCUCCGAa 5'
                       :|||||| 
Target 5' tcccagcactttgGGAGGCTg 3'
 1226 - 1246 124.00 -9.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30475179 15 COSMIC
COSN1306133 43 COSMIC
COSN5068092 44 COSMIC
COSN20047293 53 COSMIC
COSN28840869 53 COSMIC
COSN18729941 54 COSMIC
COSN28568786 54 COSMIC
COSN28570874 55 COSMIC
COSN30460316 66 COSMIC
COSN30534243 67 COSMIC
COSN16825944 98 COSMIC
COSN9402298 162 COSMIC
COSN22403933 225 COSMIC
COSN20939063 297 COSMIC
COSN6860112 298 COSMIC
COSN8201858 414 COSMIC
COSN21832866 464 COSMIC
COSN22993705 527 COSMIC
COSN21204727 735 COSMIC
COSN2065706 1349 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs374967989 3 dbSNP
rs765375214 7 dbSNP
rs1482066080 8 dbSNP
rs1046733923 9 dbSNP
rs1189906386 12 dbSNP
rs1233347618 14 dbSNP
rs1257606266 15 dbSNP
rs753011232 17 dbSNP
rs1185372540 18 dbSNP
rs1421266700 20 dbSNP
rs1410149541 22 dbSNP
rs143730965 23 dbSNP
rs202198019 25 dbSNP
rs757270066 26 dbSNP
rs780777954 29 dbSNP
rs1305368909 31 dbSNP
rs539546273 32 dbSNP
rs745609254 32 dbSNP
rs770458096 32 dbSNP
rs747071598 33 dbSNP
rs1450553279 36 dbSNP
rs779553609 38 dbSNP
rs1271981041 41 dbSNP
rs1408479379 43 dbSNP
rs1337456644 44 dbSNP
rs769742884 45 dbSNP
rs898882403 45 dbSNP
rs1362968063 46 dbSNP
rs749012114 47 dbSNP
rs1294600227 52 dbSNP
rs772289428 53 dbSNP
rs1342975541 59 dbSNP
rs983857472 62 dbSNP
rs1156707025 63 dbSNP
rs1017196317 66 dbSNP
rs961198121 82 dbSNP
rs973068920 83 dbSNP
rs1420604999 85 dbSNP
rs1408646639 86 dbSNP
rs1182839726 89 dbSNP
rs922512418 92 dbSNP
rs1307106779 98 dbSNP
rs1183641947 99 dbSNP
rs771176630 100 dbSNP
rs1218405926 106 dbSNP
rs1317832865 116 dbSNP
rs1028780383 121 dbSNP
rs1291503645 122 dbSNP
rs1264796603 127 dbSNP
rs538421146 128 dbSNP
rs1459782478 134 dbSNP
rs1142708 137 dbSNP
rs953652602 141 dbSNP
rs1315872346 142 dbSNP
rs556808695 143 dbSNP
rs1248552583 145 dbSNP
rs1360162469 147 dbSNP
rs559258724 147 dbSNP
rs985407682 148 dbSNP
rs1019586259 158 dbSNP
rs1184223100 161 dbSNP
rs1360069007 162 dbSNP
rs1042092932 166 dbSNP
rs746114870 167 dbSNP
rs946811538 169 dbSNP
rs1043780269 171 dbSNP
rs1414702206 172 dbSNP
rs977350983 176 dbSNP
rs1408768558 182 dbSNP
rs1468516087 183 dbSNP
rs924115093 187 dbSNP
rs575410516 189 dbSNP
rs1056773978 195 dbSNP
rs528333117 196 dbSNP
rs1220684011 197 dbSNP
rs1362261523 202 dbSNP
rs536296847 210 dbSNP
rs529583733 211 dbSNP
rs916027670 212 dbSNP
rs1226805254 215 dbSNP
rs1305770911 218 dbSNP
rs947853533 219 dbSNP
rs151058304 232 dbSNP
rs1044098125 238 dbSNP
rs1367143690 239 dbSNP
rs1302349337 244 dbSNP
rs905503565 252 dbSNP
rs1265167102 258 dbSNP
rs1005714811 260 dbSNP
rs140843578 261 dbSNP
rs1461419513 263 dbSNP
rs1370902345 269 dbSNP
rs770014382 275 dbSNP
rs1428793191 278 dbSNP
rs993956519 283 dbSNP
rs1428118083 286 dbSNP
rs1036315623 287 dbSNP
rs11392277 287 dbSNP
rs898828406 294 dbSNP
rs1213494551 295 dbSNP
rs1241046089 296 dbSNP
rs1253194466 301 dbSNP
rs1029556025 302 dbSNP
rs1323126398 304 dbSNP
rs1281555347 309 dbSNP
rs955276551 310 dbSNP
rs769559965 312 dbSNP
rs200435602 314 dbSNP
rs1299418689 315 dbSNP
rs985322610 316 dbSNP
rs1314015445 318 dbSNP
rs888883201 319 dbSNP
rs1481210037 321 dbSNP
rs540547871 325 dbSNP
rs1181507368 328 dbSNP
rs565168654 333 dbSNP
rs1253231979 341 dbSNP
rs1196474508 345 dbSNP
rs979960095 358 dbSNP
rs924047599 367 dbSNP
rs935521450 369 dbSNP
rs1205881821 378 dbSNP
rs1019112584 381 dbSNP
rs967567388 387 dbSNP
rs1238014650 396 dbSNP
rs1333931928 398 dbSNP
rs1308988053 402 dbSNP
rs1344690737 417 dbSNP
rs1437265033 419 dbSNP
rs1056634036 420 dbSNP
rs188470083 422 dbSNP
rs1033250050 427 dbSNP
rs918061929 433 dbSNP
rs1334102815 439 dbSNP
rs948302752 443 dbSNP
rs1470778918 456 dbSNP
rs1045301383 462 dbSNP
rs1222719952 465 dbSNP
rs1158384251 469 dbSNP
rs905533847 469 dbSNP
rs1288770501 482 dbSNP
rs1005210012 486 dbSNP
rs1038564057 487 dbSNP
rs1241416846 490 dbSNP
rs1185465509 508 dbSNP
rs896881876 509 dbSNP
rs1283772442 512 dbSNP
rs1222006744 515 dbSNP
rs991521652 523 dbSNP
rs1262268591 529 dbSNP
rs1240856901 532 dbSNP
rs1381917030 533 dbSNP
rs150145387 535 dbSNP
rs1224069737 536 dbSNP
rs950166793 537 dbSNP
rs982319842 548 dbSNP
rs1317121646 550 dbSNP
rs1266383799 551 dbSNP
rs1029462732 552 dbSNP
rs770468420 553 dbSNP
rs1490078515 564 dbSNP
rs955171345 567 dbSNP
rs562230021 575 dbSNP
rs1471323785 583 dbSNP
rs1383890864 586 dbSNP
rs1157396861 587 dbSNP
rs1018186226 594 dbSNP
rs1407886291 602 dbSNP
rs1241750501 608 dbSNP
rs1191389932 619 dbSNP
rs1448945249 621 dbSNP
rs1263643769 632 dbSNP
rs1217026593 633 dbSNP
rs968495332 639 dbSNP
rs562881205 647 dbSNP
rs1425424163 649 dbSNP
rs1036262014 652 dbSNP
rs1305006751 653 dbSNP
rs920538131 654 dbSNP
rs930266564 665 dbSNP
rs1050114577 666 dbSNP
rs773952998 669 dbSNP
rs1327800824 676 dbSNP
rs1299228875 677 dbSNP
rs1404671243 677 dbSNP
rs1364270115 682 dbSNP
rs1305421413 684 dbSNP
rs138787980 689 dbSNP
rs924049784 693 dbSNP
rs1476535723 694 dbSNP
rs1337321850 696 dbSNP
rs1008653995 698 dbSNP
rs1278960386 701 dbSNP
rs1356930542 702 dbSNP
rs1247601325 704 dbSNP
rs1288988344 705 dbSNP
rs956826569 708 dbSNP
rs866534134 716 dbSNP
rs1224711370 724 dbSNP
rs1358058091 736 dbSNP
rs1271730132 738 dbSNP
rs992221072 742 dbSNP
rs35281500 744 dbSNP
rs918091374 744 dbSNP
rs1223286758 748 dbSNP
rs1252156146 751 dbSNP
rs879719123 764 dbSNP
rs1437871387 769 dbSNP
rs1040560874 776 dbSNP
rs981054652 777 dbSNP
rs568367571 792 dbSNP
rs181201784 796 dbSNP
rs1033197671 803 dbSNP
rs957639510 804 dbSNP
rs1013295638 805 dbSNP
rs1427009475 811 dbSNP
rs1192683167 814 dbSNP
rs1478334800 815 dbSNP
rs1232859146 819 dbSNP
rs1038024843 824 dbSNP
rs1438980858 824 dbSNP
rs896784118 831 dbSNP
rs971837766 834 dbSNP
rs1320945865 835 dbSNP
rs929744849 839 dbSNP
rs1383462313 845 dbSNP
rs981548376 854 dbSNP
rs185761095 856 dbSNP
rs1444463295 864 dbSNP
rs961858898 874 dbSNP
rs971903575 876 dbSNP
rs890995121 877 dbSNP
rs1468476999 878 dbSNP
rs920487127 888 dbSNP
rs1006678399 891 dbSNP
rs17148713 894 dbSNP
rs903757328 903 dbSNP
rs1414768242 905 dbSNP
rs1001163206 908 dbSNP
rs1031021448 914 dbSNP
rs775508141 918 dbSNP
rs1441452654 926 dbSNP
rs552631117 933 dbSNP
rs992251858 936 dbSNP
rs1025055462 940 dbSNP
rs969584293 947 dbSNP
rs944408248 950 dbSNP
rs1040112666 953 dbSNP
rs1454543834 961 dbSNP
rs571105763 965 dbSNP
rs1316631126 966 dbSNP
rs17148715 968 dbSNP
rs570895783 969 dbSNP
rs1355018710 977 dbSNP
rs1228488716 979 dbSNP
rs17148718 983 dbSNP
rs1450480478 997 dbSNP
rs764045962 998 dbSNP
rs536372632 1004 dbSNP
rs1013160913 1005 dbSNP
rs1194825008 1006 dbSNP
rs918268720 1007 dbSNP
rs1272777602 1011 dbSNP
rs866822284 1018 dbSNP
rs1050842854 1021 dbSNP
rs1344449192 1022 dbSNP
rs1430278693 1022 dbSNP
rs890860170 1031 dbSNP
rs753437139 1036 dbSNP
rs1380799741 1041 dbSNP
rs191462734 1051 dbSNP
rs1241817845 1056 dbSNP
rs566506372 1058 dbSNP
rs1015656780 1068 dbSNP
rs1039551839 1074 dbSNP
rs181930778 1079 dbSNP
rs558625543 1080 dbSNP
rs17352041 1090 dbSNP
rs765342679 1096 dbSNP
rs1355078037 1103 dbSNP
rs1460681575 1105 dbSNP
rs1167517071 1106 dbSNP
rs1406550560 1112 dbSNP
rs1291622522 1113 dbSNP
rs1031300808 1114 dbSNP
rs1361770684 1117 dbSNP
rs1334682281 1128 dbSNP
rs1313517322 1138 dbSNP
rs1214256789 1139 dbSNP
rs1360097998 1140 dbSNP
rs1381907470 1144 dbSNP
rs1286935390 1147 dbSNP
rs1401562994 1148 dbSNP
rs1361103199 1150 dbSNP
rs952003551 1160 dbSNP
rs892503177 1165 dbSNP
rs1422663890 1178 dbSNP
rs1369750418 1191 dbSNP
rs574593811 1192 dbSNP
rs555944239 1200 dbSNP
rs574265395 1202 dbSNP
rs141443881 1203 dbSNP
rs560199112 1204 dbSNP
rs750544165 1206 dbSNP
rs1016449002 1207 dbSNP
rs1220978408 1210 dbSNP
rs758183991 1213 dbSNP
rs975740946 1217 dbSNP
rs1266155502 1218 dbSNP
rs1203862784 1221 dbSNP
rs375856994 1223 dbSNP
rs963839952 1232 dbSNP
rs972378730 1238 dbSNP
rs919509111 1250 dbSNP
rs1205958484 1251 dbSNP
rs1261863837 1260 dbSNP
rs527710037 1261 dbSNP
rs948924704 1269 dbSNP
rs546177735 1276 dbSNP
rs1172458920 1278 dbSNP
rs1477936391 1281 dbSNP
rs986416861 1286 dbSNP
rs777823407 1288 dbSNP
rs1429091414 1289 dbSNP
rs1197679130 1292 dbSNP
rs942483855 1295 dbSNP
rs564669797 1302 dbSNP
rs1002851799 1308 dbSNP
rs1430230213 1310 dbSNP
rs757363458 1311 dbSNP
rs137950049 1312 dbSNP
rs758422437 1314 dbSNP
rs202029617 1318 dbSNP
rs200344561 1319 dbSNP
rs550175882 1327 dbSNP
rs995581538 1342 dbSNP
rs1454274420 1343 dbSNP
rs114092556 1351 dbSNP
rs951893576 1352 dbSNP
rs1382155107 1353 dbSNP
rs529493343 1364 dbSNP
rs1404855999 1369 dbSNP
rs1046444064 1371 dbSNP
rs1174759560 1372 dbSNP
rs986383723 1378 dbSNP
rs1303448071 1386 dbSNP
rs879720596 1394 dbSNP
rs879794251 1395 dbSNP
rs879515821 1396 dbSNP
rs1017499969 1398 dbSNP
rs879613116 1399 dbSNP
rs1181799688 1404 dbSNP
rs770072510 1406 dbSNP
rs1417835963 1412 dbSNP
rs1262955842 1413 dbSNP
rs966361845 1415 dbSNP
rs905169284 1416 dbSNP
rs1002293530 1436 dbSNP
rs975688822 1442 dbSNP
rs1198521634 1458 dbSNP
rs1490908270 1459 dbSNP
rs752130652 1465 dbSNP
rs1256356566 1467 dbSNP
rs1238303807 1470 dbSNP
rs1310859423 1473 dbSNP
rs1351382497 1473 dbSNP
rs1446821722 1475 dbSNP
rs1197484911 1476 dbSNP
rs1331712731 1478 dbSNP
rs1159350482 1479 dbSNP
rs1382658602 1479 dbSNP
rs1397410428 1479 dbSNP
rs1403422654 1479 dbSNP
rs557790595 1479 dbSNP
rs548331932 1494 dbSNP
rs934368130 1495 dbSNP
rs963620729 1498 dbSNP
rs1256644837 1503 dbSNP
rs1393383514 1505 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gaccccaccccuGUCUCCGAa 5'
                      :||||||| 
Target 5' ------------UAGAGGCUu 3'
 		1 - 9
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000339397.4 | 3UTR | UAGAGGCUUUUUUUUUUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
108 hsa-miR-6819-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT358318 PANK3 pantothenate kinase 3 2 2
MIRT454719 UBQLNL ubiquilin like 2 2
MIRT471362 PEG10 paternally expressed 10 2 2
MIRT478101 DLG5 discs large MAGUK scaffold protein 5 2 4
MIRT495554 GOLGA6L4 golgin A6 family-like 4 2 2
MIRT495587 GOLGA6L10 golgin A6 family-like 10 2 2
MIRT508315 RPL18 ribosomal protein L18 2 4
MIRT529183 ADAM33 ADAM metallopeptidase domain 33 2 2
MIRT532035 FHDC1 FH2 domain containing 1 2 2
MIRT545131 ANXA5 annexin A5 2 2
MIRT567288 HNRNPL heterogeneous nuclear ribonucleoprotein L 2 2
MIRT568094 CEBPG CCAAT/enhancer binding protein gamma 2 2
MIRT573291 DLX4 distal-less homeobox 4 2 2
MIRT575169 Fam120c family with sequence similarity 120, member C 2 2
MIRT609495 DNASE1L3 deoxyribonuclease 1 like 3 2 2
MIRT611264 EHD3 EH domain containing 3 2 2
MIRT613580 POC5 POC5 centriolar protein 2 2
MIRT616520 C9orf170 chromosome 9 open reading frame 170 2 2
MIRT617098 ZNF667 zinc finger protein 667 2 2
MIRT618268 DDX51 DEAD-box helicase 51 2 2
MIRT618294 ZNF682 zinc finger protein 682 2 2
MIRT618617 SHOX short stature homeobox 2 2
MIRT619741 SRFBP1 serum response factor binding protein 1 2 2
MIRT619784 NRIP2 nuclear receptor interacting protein 2 2 2
MIRT621119 SP110 SP110 nuclear body protein 2 2
MIRT622530 RAD51 RAD51 recombinase 2 2
MIRT623088 NME6 NME/NM23 nucleoside diphosphate kinase 6 2 2
MIRT623938 FKBP14 FK506 binding protein 14 2 2
MIRT624389 CD84 CD84 molecule 2 2
MIRT624860 ABI2 abl interactor 2 2 2
MIRT628752 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT632243 VTA1 vesicle trafficking 1 2 2
MIRT632987 E2F2 E2F transcription factor 2 2 2
MIRT633695 RBM43 RNA binding motif protein 43 2 2
MIRT633766 CENPBD1 CENPB DNA-binding domain containing 1 2 2
MIRT633808 ZNF91 zinc finger protein 91 2 2
MIRT638914 CBLN2 cerebellin 2 precursor 2 2
MIRT641298 SLAMF1 signaling lymphocytic activation molecule family member 1 2 2
MIRT642123 SRCAP Snf2 related CREBBP activator protein 2 2
MIRT642179 HEBP2 heme binding protein 2 2 2
MIRT642617 CDKN3 cyclin dependent kinase inhibitor 3 2 2
MIRT643325 TMEM151B transmembrane protein 151B 2 2
MIRT644534 TMEM134 transmembrane protein 134 2 2
MIRT645820 OMA1 OMA1 zinc metallopeptidase 2 2
MIRT646093 MGST3 microsomal glutathione S-transferase 3 2 2
MIRT646861 SLC35E4 solute carrier family 35 member E4 2 2
MIRT647466 DZIP1L DAZ interacting zinc finger protein 1 like 2 2
MIRT647702 NADSYN1 NAD synthetase 1 2 2
MIRT648082 ZMIZ2 zinc finger MIZ-type containing 2 2 2
MIRT648547 TMEM169 transmembrane protein 169 2 2
MIRT648690 AP1M1 adaptor related protein complex 1 mu 1 subunit 2 2
MIRT649747 GNB5 G protein subunit beta 5 2 2
MIRT650154 ZNF426 zinc finger protein 426 2 2
MIRT650450 CPXM2 carboxypeptidase X, M14 family member 2 2 2
MIRT650943 CTNS cystinosin, lysosomal cystine transporter 2 2
MIRT651544 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT652304 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT652890 SYVN1 synoviolin 1 2 2
MIRT654222 RNF19B ring finger protein 19B 2 2
MIRT654676 PSMB5 proteasome subunit beta 5 2 2
MIRT658249 FAXC failed axon connections homolog 2 2
MIRT658363 FAM65B RHO family interacting cell polarization regulator 2 2 2
MIRT659622 CELF1 CUGBP Elav-like family member 1 2 2
MIRT660171 BNIP3L BCL2 interacting protein 3 like 2 2
MIRT660634 ANKRD52 ankyrin repeat domain 52 2 2
MIRT662428 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT662984 PAK3 p21 (RAC1) activated kinase 3 2 2
MIRT663939 ZNF554 zinc finger protein 554 2 2
MIRT666960 PKHD1 PKHD1, fibrocystin/polyductin 2 2
MIRT667945 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2 2
MIRT668847 CYCS cytochrome c, somatic 2 2
MIRT671792 RGS17 regulator of G protein signaling 17 2 2
MIRT672382 RPL37 ribosomal protein L37 2 2
MIRT673516 TNFAIP8L1 TNF alpha induced protein 8 like 1 2 4
MIRT674716 FAM73A mitoguardin 1 2 2
MIRT676352 KLF8 Kruppel like factor 8 2 2
MIRT677820 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT678440 PDE4C phosphodiesterase 4C 2 2
MIRT678499 ARHGEF39 Rho guanine nucleotide exchange factor 39 2 2
MIRT679243 LRP10 LDL receptor related protein 10 2 2
MIRT693607 SLC39A1 solute carrier family 39 member 1 2 2
MIRT695927 ZNF174 zinc finger protein 174 2 2
MIRT697987 TSPAN6 tetraspanin 6 2 2
MIRT700821 PHLDA2 pleckstrin homology like domain family A member 2 2 2
MIRT701350 NR4A3 nuclear receptor subfamily 4 group A member 3 2 2
MIRT702348 KLHL7 kelch like family member 7 2 2
MIRT703387 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT703883 ERBB2IP erbb2 interacting protein 2 2
MIRT708237 PPP1R26 protein phosphatase 1 regulatory subunit 26 2 2
MIRT708629 NUDT18 nudix hydrolase 18 2 2
MIRT708990 CABP4 calcium binding protein 4 2 2
MIRT709804 FOXE1 forkhead box E1 2 2
MIRT710203 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT710248 VAMP1 vesicle associated membrane protein 1 2 2
MIRT710281 FGF1 fibroblast growth factor 1 2 2
MIRT712992 IRGQ immunity related GTPase Q 2 2
MIRT713887 MOB3A MOB kinase activator 3A 2 2
MIRT715600 ADAM17 ADAM metallopeptidase domain 17 2 2
MIRT715639 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT715686 FRK fyn related Src family tyrosine kinase 2 2
MIRT717053 WIZ widely interspaced zinc finger motifs 2 2
MIRT717611 DSTYK dual serine/threonine and tyrosine protein kinase 2 2
MIRT721539 DKK3 dickkopf WNT signaling pathway inhibitor 3 2 2
MIRT722096 SUSD1 sushi domain containing 1 2 2
MIRT722435 HRNR hornerin 2 2
MIRT722855 NEGR1 neuronal growth regulator 1 2 2
MIRT724621 SNAP25 synaptosome associated protein 25 2 2
MIRT724777 PSG4 pregnancy specific beta-1-glycoprotein 4 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6819 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-6819-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-6819-3p Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-miR-6819-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-6819-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-6819-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-6819-3p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-6819-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)

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