pre-miRNA Information
pre-miRNA hsa-mir-216a   
Genomic Coordinates chr2: 55988950 - 55989059
Description Homo sapiens miR-216a stem-loop
Comment This human miRNA was predicted by computational methods using conservation with mouse and Fugu rubripes sequences .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-216a-5p
Sequence 19| UAAUCUCAGCUGGCAACUGUGA |40
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 15 2 - 55989027 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs757094946 2 dbSNP
rs746980700 8 dbSNP
rs1249388997 12 dbSNP
rs1188616124 15 dbSNP
rs1490501989 19 dbSNP
rs1465789697 20 dbSNP
rs370221981 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
BA0G4V miR-216a Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Tissue .
BA0G4V miR-216a Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Plasma MiRNA qPCR analyses
Gene Information
Gene Symbol NNT   
Synonyms GCCD4
Description nicotinamide nucleotide transhydrogenase
Transcript NM_012343   
Other Transcripts NM_182977   
Expression
Putative miRNA Targets on NNT
3'UTR of NNT
(miRNA target sites are highlighted)
>NNT|NM_012343|3'UTR
   1 ATATTAAGGATCAAGCTGTTAGCTAATAATGCCACCTCTGCAGTTTTGGGAACAGGCAAATAAAGTATCAGTATACATGG
  81 TGATGTACATCTGTAGCAAAGCTCTTGGAGAAAATGAAGACTGAAGAAAGCAAAGCAAAAACTGTATAGAGAGATTTTTC
 161 AAAAGCAGTAATCCCTCAATTTTAAAAAAGGATTGAAAATTCTAAATGTCTTTCTGTGCATATTTTTTGTGTTAGGAATC
 241 AAAAGTATTTTATAAAAGGAGAAAGAACAGCCTCATTTTAGATGTAGTCCTGTTGGATTTTTTATGCCTCCTCAGTAACC
 321 AGAAATGTTTTAAAAAACTAAGTGTTTAGGATTTCAAGACAACATTATACATGGCTCTGAAATATCTGACACAATGTAAA
 401 CATTGCAGGCACCTGCATTTTATGTTTTTTTTTTCAACAAATGTGACTAATTTGAAACTTTTATGAACTTCTGAGCTGTC
 481 CCCTTGCAATTCAACCGCAGTTTGAATTAATCATATCAAATCAGTTTTAATTTTTTAAATTGTACTTCAGAGTCTATATT
 561 TCAAGGGCACATTTTCTCACTACTATTTTAATACATTAAAGGACTAAATAATCTTTCAGAGATGCTGGAAACAAATCATT
 641 TGCTTTATATGTTTCATTAGAATACCAATGAAACATACAACTTGAAAATTAGTAATAGTATTTTTGAAGATCCCATTTCT
 721 AATTGGAGATCTCTTTAATTTCGATCAACTTATAATGTGTAGTACTATATTAAGTGCACTTGAGTGGAATTCAACATTTG
 801 ACTAATAAAATGAGTTCATCATGTTGGCAAGTGATGTGGCAATTATCTCTGGTGACAAAAGAGTAAAATCAAATATTTCT
 881 GCCTGTTACAAATATCAAGGAAGACCTGCTACTATGAAATAGATGACATTAATCTGTCTTCACTGTTTATAATACGGATG
 961 GATTTTTTTTCAAATCAGTGTGTGTTTTGAGGTCTTATGTAATTGATGACATTTGAGAGAAATGGTGGCTTTTTTTAGCT
1041 ACCTCTTTGTTCATTTAAGCACCAGTAAAGATCATGTCTTTTTATAGAAGTGTAGATTTTCTTTGTGACTTTGCTATCGT
1121 GCCTAAAGCTCTAAATATAGGTGAATGTGTGATGAATACTCAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' agUGUCAACGGUCGACUCUaau 5'
            |: | || || :|||||   
Target 5' taATTGATGACATTTGAGAgaa 3'
1000 - 1021 120.00 -6.92
2
miRNA  3' agugucaacggucgaCUCUAAu 5'
                         |||||| 
Target 5' caaaaactgtatagaGAGATTt 3'
136 - 157 120.00 -8.50
3
miRNA  3' aguGUCA-ACGGUCGACUCUAau 5'
             |||| ||:   :||||:|  
Target 5' aatCAGTGTGTGTTTTGAGGTct 3'
973 - 995 119.00 -10.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM240903 1 COSMIC
COSN31502248 7 COSMIC
COSN30497304 13 COSMIC
COSN5076842 26 COSMIC
COSN30535149 68 COSMIC
COSN31509711 70 COSMIC
COSN30191290 88 COSMIC
COSN31502465 167 COSMIC
COSN20101203 190 COSMIC
COSN20101204 435 COSMIC
COSN20566433 506 COSMIC
COSN15734450 559 COSMIC
COSN29618111 618 COSMIC
COSN8631079 1004 COSMIC
COSN14616786 1091 COSMIC
COSN15343447 1286 COSMIC
COSN23106773 1387 COSMIC
COSN25088279 1428 COSMIC
COSN9447607 1527 COSMIC
COSN23228947 1715 COSMIC
COSN27995977 1988 COSMIC
COSN27304089 2074 COSMIC
COSN16501844 2176 COSMIC
COSN17226150 2269 COSMIC
COSN7942993 2331 COSMIC
COSN19552123 2356 COSMIC
COSN28505059 2483 COSMIC
COSN27755851 2848 COSMIC
COSN2107110 2893 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs922340043 5 dbSNP
rs1278045307 10 dbSNP
rs945738367 16 dbSNP
rs1216350199 17 dbSNP
rs750730374 19 dbSNP
rs756238212 23 dbSNP
rs191475277 28 dbSNP
rs754329623 30 dbSNP
rs1269410935 31 dbSNP
rs1163048024 35 dbSNP
rs755463308 36 dbSNP
rs55984047 37 dbSNP
rs925578528 43 dbSNP
rs16873502 51 dbSNP
rs1056099615 56 dbSNP
rs147932866 58 dbSNP
rs1225304813 60 dbSNP
rs1357969918 63 dbSNP
rs1288920472 64 dbSNP
rs1244671407 66 dbSNP
rs1317128931 69 dbSNP
rs894431719 71 dbSNP
rs1221722203 76 dbSNP
rs534489214 78 dbSNP
rs1476458045 82 dbSNP
rs1054833510 84 dbSNP
rs1363686799 85 dbSNP
rs184272260 86 dbSNP
rs948794691 89 dbSNP
rs897667100 92 dbSNP
rs1157116177 93 dbSNP
rs1008185384 104 dbSNP
rs1418742046 117 dbSNP
rs1044522730 136 dbSNP
rs1339122870 142 dbSNP
rs907307577 145 dbSNP
rs1019612724 148 dbSNP
rs1268874974 148 dbSNP
rs1333144780 149 dbSNP
rs1027753514 155 dbSNP
rs1261990766 156 dbSNP
rs371409962 161 dbSNP
rs777029045 165 dbSNP
rs538347397 166 dbSNP
rs1283657135 167 dbSNP
rs1225174067 179 dbSNP
rs34053391 184 dbSNP
rs1056248207 193 dbSNP
rs886998545 195 dbSNP
rs558187103 209 dbSNP
rs187591100 217 dbSNP
rs113832882 221 dbSNP
rs1407177291 223 dbSNP
rs34304579 223 dbSNP
rs1016993800 230 dbSNP
rs962447762 232 dbSNP
rs996992904 234 dbSNP
rs1021109684 236 dbSNP
rs1028038942 239 dbSNP
rs1430834954 241 dbSNP
rs1262759896 246 dbSNP
rs1202902062 256 dbSNP
rs1464148520 258 dbSNP
rs1448813717 260 dbSNP
rs955110685 263 dbSNP
rs1191606833 265 dbSNP
rs1380005595 269 dbSNP
rs1321078740 273 dbSNP
rs1263031790 276 dbSNP
rs1228013244 280 dbSNP
rs1328171801 283 dbSNP
rs1293496408 284 dbSNP
rs986942421 294 dbSNP
rs1383794136 295 dbSNP
rs1338872730 297 dbSNP
rs924785805 305 dbSNP
rs1405752193 311 dbSNP
rs1178986143 315 dbSNP
rs1168889254 323 dbSNP
rs1376253083 332 dbSNP
rs977154098 338 dbSNP
rs925746350 339 dbSNP
rs745989161 341 dbSNP
rs956261921 343 dbSNP
rs1448279492 356 dbSNP
rs935663440 361 dbSNP
rs991204921 363 dbSNP
rs1184998443 369 dbSNP
rs1171627324 373 dbSNP
rs1255177142 376 dbSNP
rs1196210174 390 dbSNP
rs1341372225 396 dbSNP
rs915568418 410 dbSNP
rs73753606 411 dbSNP
rs914552447 420 dbSNP
rs1045642830 425 dbSNP
rs138980708 425 dbSNP
rs796540619 425 dbSNP
rs1340145074 426 dbSNP
rs111607585 427 dbSNP
rs770327974 428 dbSNP
rs1394785480 435 dbSNP
rs1339708449 441 dbSNP
rs1167783098 442 dbSNP
rs1425868852 458 dbSNP
rs1405447817 460 dbSNP
rs1385269456 462 dbSNP
rs796462613 464 dbSNP
rs574685772 465 dbSNP
rs540520330 469 dbSNP
rs1007966393 497 dbSNP
rs141702531 498 dbSNP
rs184650537 500 dbSNP
rs886967328 523 dbSNP
rs1294008090 528 dbSNP
rs1243941582 529 dbSNP
rs1355900594 537 dbSNP
rs72760484 538 dbSNP
rs1285441269 557 dbSNP
rs1241463430 577 dbSNP
rs546335560 583 dbSNP
rs1334299334 586 dbSNP
rs1038325107 591 dbSNP
rs368502379 596 dbSNP
rs1368059165 600 dbSNP
rs1304417628 601 dbSNP
rs1403165755 605 dbSNP
rs1412452390 612 dbSNP
rs1021243967 621 dbSNP
rs1470973113 623 dbSNP
rs1361811667 629 dbSNP
rs1181241049 637 dbSNP
rs1265953367 640 dbSNP
rs1480712790 650 dbSNP
rs1271042677 651 dbSNP
rs143831033 652 dbSNP
rs1183001907 656 dbSNP
rs1220162371 669 dbSNP
rs372923830 671 dbSNP
rs1451047493 675 dbSNP
rs1363967283 680 dbSNP
rs751693152 687 dbSNP
rs547287174 688 dbSNP
rs1348861254 690 dbSNP
rs996486777 698 dbSNP
rs1224571947 699 dbSNP
rs966846776 702 dbSNP
rs531818374 711 dbSNP
rs1281860091 716 dbSNP
rs1436410357 725 dbSNP
rs1359324110 731 dbSNP
rs1001072858 732 dbSNP
rs1402058516 734 dbSNP
rs1424805920 739 dbSNP
rs1028424046 743 dbSNP
rs1480600537 744 dbSNP
rs1365415851 755 dbSNP
rs190318810 758 dbSNP
rs116409496 766 dbSNP
rs971052559 776 dbSNP
rs768906780 788 dbSNP
rs1238208509 794 dbSNP
rs1204550443 795 dbSNP
rs562571421 797 dbSNP
rs181406943 803 dbSNP
rs1360241798 804 dbSNP
rs1223955674 805 dbSNP
rs1264142172 808 dbSNP
rs1488452961 814 dbSNP
rs1031824317 821 dbSNP
rs1363326284 836 dbSNP
rs1270251246 838 dbSNP
rs151107527 840 dbSNP
rs760421909 845 dbSNP
rs1196706064 851 dbSNP
rs1432359179 857 dbSNP
rs990798324 862 dbSNP
rs1240379748 877 dbSNP
rs1319398540 882 dbSNP
rs377326235 889 dbSNP
rs566138928 890 dbSNP
rs1021840802 897 dbSNP
rs970737217 925 dbSNP
rs1176377341 937 dbSNP
rs1379369038 940 dbSNP
rs1048923167 942 dbSNP
rs980099074 949 dbSNP
rs1169721064 950 dbSNP
rs1447663487 952 dbSNP
rs928669823 956 dbSNP
rs943430028 957 dbSNP
rs1241655396 963 dbSNP
rs202207795 963 dbSNP
rs1209921383 965 dbSNP
rs1308591549 966 dbSNP
rs768190254 977 dbSNP
rs1457376191 978 dbSNP
rs1298721585 979 dbSNP
rs1452872956 998 dbSNP
rs1384604946 1000 dbSNP
rs184732363 1004 dbSNP
rs1444376366 1012 dbSNP
rs766180637 1014 dbSNP
rs189141866 1019 dbSNP
rs1172375071 1023 dbSNP
rs1308798601 1024 dbSNP
rs1383817689 1027 dbSNP
rs14491 1030 dbSNP
rs901830628 1030 dbSNP
rs983540716 1036 dbSNP
rs908375322 1037 dbSNP
rs1310700223 1038 dbSNP
rs1411975325 1042 dbSNP
rs750954766 1044 dbSNP
rs776246599 1046 dbSNP
rs997538497 1056 dbSNP
rs1038613433 1064 dbSNP
rs898389247 1065 dbSNP
rs1202983967 1067 dbSNP
rs1042657946 1073 dbSNP
rs932572547 1092 dbSNP
rs1049409430 1094 dbSNP
rs568648829 1096 dbSNP
rs537939919 1103 dbSNP
rs1228762258 1108 dbSNP
rs890817847 1119 dbSNP
rs1007976575 1120 dbSNP
rs1456711013 1122 dbSNP
rs1373729657 1125 dbSNP
rs1031456791 1126 dbSNP
rs1299699808 1129 dbSNP
rs1198411949 1130 dbSNP
rs1032471064 1139 dbSNP
rs891544513 1141 dbSNP
rs554516664 1148 dbSNP
rs1164280990 1149 dbSNP
rs1012640047 1150 dbSNP
rs1011724622 1160 dbSNP
rs1022699473 1174 dbSNP
rs1180529692 1180 dbSNP
rs113936896 1182 dbSNP
rs970323680 1188 dbSNP
rs981114928 1189 dbSNP
rs1489142251 1196 dbSNP
rs980785902 1197 dbSNP
rs112625662 1212 dbSNP
rs1483388425 1227 dbSNP
rs533854658 1230 dbSNP
rs1317187401 1231 dbSNP
rs1183058964 1233 dbSNP
rs1410955171 1243 dbSNP
rs1308855199 1245 dbSNP
rs950603747 1247 dbSNP
rs1349797312 1251 dbSNP
rs1283779586 1252 dbSNP
rs1422782262 1254 dbSNP
rs186242454 1258 dbSNP
rs985118071 1265 dbSNP
rs1171286929 1269 dbSNP
rs1035652394 1281 dbSNP
rs1425772541 1283 dbSNP
rs190725045 1284 dbSNP
rs546247932 1285 dbSNP
rs716960 1286 dbSNP
rs569254928 1306 dbSNP
rs1202164842 1313 dbSNP
rs1431979383 1327 dbSNP
rs974834692 1336 dbSNP
rs1264618564 1362 dbSNP
rs1485984751 1362 dbSNP
rs1269706789 1366 dbSNP
rs200317908 1366 dbSNP
rs1318719390 1368 dbSNP
rs1434676407 1368 dbSNP
rs181517819 1368 dbSNP
rs70997432 1368 dbSNP
rs1407251401 1370 dbSNP
rs138029232 1376 dbSNP
rs923387764 1377 dbSNP
rs1464966396 1384 dbSNP
rs1377618041 1385 dbSNP
rs1428527483 1387 dbSNP
rs963814101 1387 dbSNP
rs397811308 1388 dbSNP
rs973903171 1389 dbSNP
rs1448477549 1390 dbSNP
rs919782806 1398 dbSNP
rs1412012677 1400 dbSNP
rs796364031 1412 dbSNP
rs1042377469 1414 dbSNP
rs933299980 1414 dbSNP
rs1280570087 1420 dbSNP
rs1383736092 1430 dbSNP
rs1339116599 1436 dbSNP
rs902518088 1438 dbSNP
rs936914025 1440 dbSNP
rs1299299172 1444 dbSNP
rs1463955363 1458 dbSNP
rs1264179002 1460 dbSNP
rs1166122884 1469 dbSNP
rs576649903 1470 dbSNP
rs1385402134 1472 dbSNP
rs895304074 1479 dbSNP
rs1440545691 1490 dbSNP
rs1255189474 1492 dbSNP
rs1211773377 1494 dbSNP
rs1235439736 1501 dbSNP
rs186241226 1505 dbSNP
rs1022667070 1509 dbSNP
rs1227682875 1518 dbSNP
rs1360439986 1524 dbSNP
rs1286239060 1528 dbSNP
rs1242861548 1532 dbSNP
rs943650011 1539 dbSNP
rs10069201 1545 dbSNP
rs1308112638 1552 dbSNP
rs1476817864 1560 dbSNP
rs1369188982 1566 dbSNP
rs1002588339 1569 dbSNP
rs141085785 1573 dbSNP
rs1169923255 1575 dbSNP
rs1425578312 1583 dbSNP
rs1428623934 1588 dbSNP
rs891517855 1596 dbSNP
rs1025898200 1597 dbSNP
rs1471587929 1600 dbSNP
rs1011772262 1609 dbSNP
rs1043214033 1612 dbSNP
rs1174212131 1616 dbSNP
rs950455474 1629 dbSNP
rs150309124 1630 dbSNP
rs1473538862 1638 dbSNP
rs137878316 1640 dbSNP
rs1001735752 1652 dbSNP
rs964571277 1653 dbSNP
rs1490549805 1657 dbSNP
rs1339044076 1677 dbSNP
rs541374820 1683 dbSNP
rs556122133 1683 dbSNP
rs1035869548 1685 dbSNP
rs1292081334 1715 dbSNP
rs564408837 1716 dbSNP
rs1208323495 1722 dbSNP
rs1355850203 1730 dbSNP
rs975014237 1731 dbSNP
rs1230550186 1735 dbSNP
rs960284123 1744 dbSNP
rs533432865 1751 dbSNP
rs1288335224 1759 dbSNP
rs923106654 1769 dbSNP
rs933352457 1772 dbSNP
rs1370166778 1774 dbSNP
rs1014891447 1776 dbSNP
rs1324907943 1786 dbSNP
rs1403266789 1791 dbSNP
rs963480981 1808 dbSNP
rs1275985075 1815 dbSNP
rs1159634143 1825 dbSNP
rs978189000 1827 dbSNP
rs973918660 1828 dbSNP
rs1181423429 1840 dbSNP
rs1480702625 1844 dbSNP
rs34289650 1849 dbSNP
rs1196780007 1850 dbSNP
rs1451259815 1851 dbSNP
rs954046858 1861 dbSNP
rs142465518 1865 dbSNP
rs1287497877 1871 dbSNP
rs985296925 1873 dbSNP
rs531311946 1875 dbSNP
rs1487050199 1895 dbSNP
rs936697257 1897 dbSNP
rs912442275 1898 dbSNP
rs1267862181 1922 dbSNP
rs943951304 1932 dbSNP
rs190700755 1935 dbSNP
rs912282013 1935 dbSNP
rs948240691 1935 dbSNP
rs144632030 1936 dbSNP
rs1436796356 1944 dbSNP
rs1386229255 1954 dbSNP
rs1002557034 1970 dbSNP
rs1414988198 1971 dbSNP
rs1189260766 1973 dbSNP
rs1427100028 1973 dbSNP
rs1170739593 1977 dbSNP
rs1026047339 1979 dbSNP
rs1242755703 1989 dbSNP
rs35429460 1999 dbSNP
rs1463681109 2000 dbSNP
rs1420576389 2009 dbSNP
rs947156533 2012 dbSNP
rs554487506 2020 dbSNP
rs1277199884 2025 dbSNP
rs1219141254 2029 dbSNP
rs1043232773 2030 dbSNP
rs905620194 2037 dbSNP
rs182894790 2046 dbSNP
rs1230194820 2047 dbSNP
rs1362514884 2050 dbSNP
rs746565356 2051 dbSNP
rs574967807 2053 dbSNP
rs1359602026 2062 dbSNP
rs1448572761 2062 dbSNP
rs974660159 2062 dbSNP
rs1352130089 2070 dbSNP
rs62368580 2076 dbSNP
rs1030144815 2077 dbSNP
rs954540069 2098 dbSNP
rs1389710173 2109 dbSNP
rs1057248518 2123 dbSNP
rs1484474756 2127 dbSNP
rs1374556599 2129 dbSNP
rs896043195 2131 dbSNP
rs116460111 2133 dbSNP
rs1274755465 2175 dbSNP
rs1206599911 2179 dbSNP
rs1311072440 2179 dbSNP
rs138690778 2183 dbSNP
rs1014908013 2185 dbSNP
rs963746664 2186 dbSNP
rs539734075 2201 dbSNP
rs1381128156 2202 dbSNP
rs1282172726 2218 dbSNP
rs1447230018 2221 dbSNP
rs943790203 2222 dbSNP
rs1309941805 2223 dbSNP
rs989922099 2227 dbSNP
rs994922075 2231 dbSNP
rs1245884518 2232 dbSNP
rs535252358 2233 dbSNP
rs1029455819 2235 dbSNP
rs1165806997 2240 dbSNP
rs1180734847 2245 dbSNP
rs953442930 2248 dbSNP
rs1425746535 2250 dbSNP
rs985264260 2254 dbSNP
rs770323169 2255 dbSNP
rs991059468 2256 dbSNP
rs535618147 2260 dbSNP
rs930166943 2263 dbSNP
rs1047465813 2265 dbSNP
rs1481816115 2268 dbSNP
rs965272324 2269 dbSNP
rs988768892 2271 dbSNP
rs912890742 2281 dbSNP
rs947009588 2282 dbSNP
rs978453382 2289 dbSNP
rs1350878579 2290 dbSNP
rs886219341 2300 dbSNP
rs576338824 2303 dbSNP
rs1294144419 2311 dbSNP
rs1459658318 2317 dbSNP
rs1404062264 2318 dbSNP
rs927012138 2328 dbSNP
rs545501986 2331 dbSNP
rs879873788 2332 dbSNP
rs1323535305 2337 dbSNP
rs1458152625 2339 dbSNP
rs1414625543 2340 dbSNP
rs1057215333 2341 dbSNP
rs1180699720 2351 dbSNP
rs1472528876 2355 dbSNP
rs1454708141 2356 dbSNP
rs1249237427 2361 dbSNP
rs1401463483 2366 dbSNP
rs1191213890 2369 dbSNP
rs1489260099 2370 dbSNP
rs375050183 2371 dbSNP
rs1005974583 2379 dbSNP
rs896010658 2395 dbSNP
rs541965021 2402 dbSNP
rs1037053562 2405 dbSNP
rs1329667304 2406 dbSNP
rs149288188 2408 dbSNP
rs995205017 2425 dbSNP
rs1029011000 2428 dbSNP
rs1237642410 2438 dbSNP
rs1284307072 2449 dbSNP
rs1302084744 2452 dbSNP
rs1357900969 2454 dbSNP
rs889193512 2458 dbSNP
rs1226517628 2460 dbSNP
rs1293211687 2468 dbSNP
rs1436052473 2477 dbSNP
rs1391329588 2478 dbSNP
rs368384741 2483 dbSNP
rs1019458211 2484 dbSNP
rs1378651636 2486 dbSNP
rs1434456758 2491 dbSNP
rs1422416898 2497 dbSNP
rs965242552 2499 dbSNP
rs554065251 2509 dbSNP
rs1200311133 2517 dbSNP
rs1020583394 2526 dbSNP
rs372619819 2530 dbSNP
rs1206523238 2534 dbSNP
rs202239317 2535 dbSNP
rs572355467 2537 dbSNP
rs968683154 2549 dbSNP
rs978804878 2554 dbSNP
rs1229459230 2555 dbSNP
rs1302715540 2558 dbSNP
rs926989622 2559 dbSNP
rs1318968468 2563 dbSNP
rs1434913377 2571 dbSNP
rs1403340810 2572 dbSNP
rs1188555036 2573 dbSNP
rs1370244178 2574 dbSNP
rs1471884547 2585 dbSNP
rs1391560445 2588 dbSNP
rs937073568 2593 dbSNP
rs1163183444 2611 dbSNP
rs1256562066 2612 dbSNP
rs1272100746 2614 dbSNP
rs1424971300 2615 dbSNP
rs1467454369 2622 dbSNP
rs1169009463 2623 dbSNP
rs1397621250 2626 dbSNP
rs1344400623 2631 dbSNP
rs1390433432 2633 dbSNP
rs1334461070 2644 dbSNP
rs1226940269 2651 dbSNP
rs992576590 2653 dbSNP
rs1341732619 2656 dbSNP
rs572572728 2657 dbSNP
rs1292529834 2661 dbSNP
rs546080096 2662 dbSNP
rs1402046464 2663 dbSNP
rs1220189603 2670 dbSNP
rs940826694 2680 dbSNP
rs1036533030 2681 dbSNP
rs1255955202 2682 dbSNP
rs899387731 2683 dbSNP
rs954510662 2685 dbSNP
rs1201233547 2692 dbSNP
rs1368855922 2694 dbSNP
rs999398639 2701 dbSNP
rs541253228 2703 dbSNP
rs958330566 2706 dbSNP
rs187918518 2707 dbSNP
rs533494108 2708 dbSNP
rs1272534080 2713 dbSNP
rs916546539 2713 dbSNP
rs1186946496 2715 dbSNP
rs1264462584 2716 dbSNP
rs1267615630 2717 dbSNP
rs1289583109 2717 dbSNP
rs397997610 2717 dbSNP
rs564776546 2717 dbSNP
rs70997433 2717 dbSNP
rs889162510 2718 dbSNP
rs1008980763 2722 dbSNP
rs1351834963 2722 dbSNP
rs1019005703 2724 dbSNP
rs1164633688 2724 dbSNP
rs1456251670 2730 dbSNP
rs892557002 2736 dbSNP
rs1169209808 2742 dbSNP
rs1159869404 2746 dbSNP
rs1473508581 2751 dbSNP
rs928257794 2754 dbSNP
rs543664621 2757 dbSNP
rs1466932107 2761 dbSNP
rs1047637756 2774 dbSNP
rs1452409076 2775 dbSNP
rs562156247 2785 dbSNP
rs910052633 2787 dbSNP
rs576750568 2791 dbSNP
rs191223856 2792 dbSNP
rs1230801147 2795 dbSNP
rs1412211304 2795 dbSNP
rs1327630968 2799 dbSNP
rs1277270546 2802 dbSNP
rs1440927520 2810 dbSNP
rs1037468721 2811 dbSNP
rs1020130624 2818 dbSNP
rs553315800 2824 dbSNP
rs1438218288 2828 dbSNP
rs1393496192 2831 dbSNP
rs1320922200 2847 dbSNP
rs752584791 2848 dbSNP
rs1409574201 2852 dbSNP
rs900153454 2859 dbSNP
rs1379417712 2865 dbSNP
rs1197066900 2881 dbSNP
rs1341009530 2883 dbSNP
rs969025501 2884 dbSNP
rs1249053672 2885 dbSNP
rs1245633299 2898 dbSNP
rs375405207 2907 dbSNP
rs1401741945 2908 dbSNP
rs1284251718 2910 dbSNP
rs1220293207 2938 dbSNP
rs1000140021 2942 dbSNP
rs1345157735 2961 dbSNP
rs1276289701 2968 dbSNP
rs1231652548 2969 dbSNP
rs995866055 2973 dbSNP
rs1298061658 2978 dbSNP
rs1033974022 2980 dbSNP
rs958398983 2981 dbSNP
rs568177629 2982 dbSNP
rs1317608100 2984 dbSNP
rs1414933779 2987 dbSNP
rs916955575 2987 dbSNP
rs1404474833 2990 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084078. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' agugucaacggucGACUCUAAu 5'
                       |||||||| 
Target 5' -------------CUGAGAUUa 3'
1 - 9
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000264663.5 | 3UTR | UUAAGAUCUGUGUAUGUGUGUGUGUGUGUGUGUGCGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084078
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep2_AbnovaAb
Location of target site ENST00000264663.5 | 3UTR | CUGAGAUUAAGAUCUGUGUAUGUGUGUGUGUGUGUGUGUGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer -0.611 7.6e-4 -0.619 6.3e-4 24 Click to see details
GSE28260 Renal cortex and medulla 0.582 1.8e-2 0.444 6.4e-2 13 Click to see details
GSE42095 Differentiated embryonic stem cells 0.253 1.2e-1 0.354 4.9e-2 23 Click to see details
GSE17306 Multiple myeloma -0.142 1.7e-1 0.327 1.1e-2 49 Click to see details
GSE26953 Aortic valvular endothelial cells -0.187 1.9e-1 -0.272 9.9e-2 24 Click to see details
GSE32688 Pancreatic cancer -0.152 2.0e-1 -0.174 1.7e-1 32 Click to see details
GSE21849 B cell lymphoma 0.147 2.2e-1 0.258 8.8e-2 29 Click to see details
GSE38226 Liver fibrosis 0.161 2.4e-1 0.311 8.5e-2 21 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.154 2.6e-1 -0.376 5.1e-2 20 Click to see details
GSE19350 CNS germ cell tumors -0.176 2.9e-1 0.226 2.4e-1 12 Click to see details
GSE14794 Lymphoblastoid cells 0.054 3.1e-1 -0.055 3.0e-1 90 Click to see details
GSE17498 Multiple myeloma 0.079 3.1e-1 0.067 3.4e-1 40 Click to see details
GSE27834 Pluripotent stem cells 0.064 4.1e-1 0.359 8.6e-2 16 Click to see details
GSE21687 Ependynoma primary tumors 0.02 4.4e-1 -0.227 3.6e-2 64 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.033 4.4e-1 0.463 9.9e-3 25 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.032 4.4e-1 0.218 1.5e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
PAAD 0.886 0.06 1.000 0.5 4 Click to see details
ESCA 0.673 0.16 0.800 0.1 4 Click to see details
LIHC 0.134 0.19 0.102 0.25 45 Click to see details
KICH -0.258 0.22 -0.318 0.17 11 Click to see details
UCEC -0.262 0.23 -0.297 0.2 10 Click to see details
BRCA 0.145 0.24 0.166 0.21 25 Click to see details
KIRC 0.11 0.29 0.028 0.44 29 Click to see details
LUSC -0.125 0.3 -0.066 0.39 20 Click to see details
KIRP 0.115 0.32 0.121 0.32 18 Click to see details
HNSC -0.086 0.35 -0.107 0.31 23 Click to see details
CHOL 0.119 0.39 0.024 0.48 8 Click to see details
PRAD 0.052 0.39 0.050 0.39 31 Click to see details
BLCA -0.04 0.46 -0.139 0.35 10 Click to see details
STAD 0.025 0.46 0.224 0.17 20 Click to see details
THCA -0.009 0.48 0.055 0.36 47 Click to see details
LUAD 0.022 0.48 0.350 0.18 9 Click to see details
LUAD 0.022 0.48 0.350 0.18 9 Click to see details
LUAD 0.022 0.48 0.350 0.18 9 Click to see details
148 hsa-miR-216a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000534 PTEN phosphatase and tensin homolog 4 3
MIRT005018 SIRT1 sirtuin 1 3 1
MIRT005964 CDC42 cell division cycle 42 2 1
MIRT005969 CD44 CD44 molecule (Indian blood group) 2 1
MIRT007154 SMAD7 SMAD family member 7 1 1
MIRT054887 BECN1 beclin 1 5 3
MIRT067588 METAP2 methionyl aminopeptidase 2 2 6
MIRT099144 MYLIP myosin regulatory light chain interacting protein 2 12
MIRT162313 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT230668 DFFA DNA fragmentation factor subunit alpha 2 2
MIRT256274 PHAX phosphorylated adaptor for RNA export 2 2
MIRT386817 RAD51L3-RFFL RAD51L3-RFFL readthrough 2 2
MIRT386825 RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase 2 2
MIRT438816 HNF4A hepatocyte nuclear factor 4 alpha 1 1
MIRT464699 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465962 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466046 TMEM189 transmembrane protein 189 2 2
MIRT466482 TECPR2 tectonin beta-propeller repeat containing 2 2 7
MIRT472209 NGFRAP1 brain expressed X-linked 3 2 4
MIRT472562 NACC1 nucleus accumbens associated 1 2 4
MIRT478921 CPS1 carbamoyl-phosphate synthase 1 2 2
MIRT480121 CALR calreticulin 2 2
MIRT497754 OXGR1 oxoglutarate receptor 1 2 2
MIRT497967 TWISTNB TWIST neighbor 2 2
MIRT502882 CDK4 cyclin dependent kinase 4 2 8
MIRT510191 MON1B MON1 homolog B, secretory trafficking associated 2 4
MIRT512407 CD84 CD84 molecule 2 2
MIRT513739 PSD3 pleckstrin and Sec7 domain containing 3 2 4
MIRT526257 DROSHA drosha ribonuclease III 2 2
MIRT528968 FAM19A3 family with sequence similarity 19 member A3, C-C motif chemokine like 2 2
MIRT529599 C6orf132 chromosome 6 open reading frame 132 2 2
MIRT529776 ZNF486 zinc finger protein 486 2 2
MIRT530110 PSAPL1 prosaposin like 1 (gene/pseudogene) 2 2
MIRT530504 FADS6 fatty acid desaturase 6 2 2
MIRT531437 PAK1 p21 (RAC1) activated kinase 1 2 2
MIRT534445 SDR16C5 short chain dehydrogenase/reductase family 16C member 5 2 2
MIRT537286 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT538451 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT543085 ACTB actin beta 2 2
MIRT550982 ZNF254 zinc finger protein 254 2 2
MIRT556259 MAPRE2 microtubule associated protein RP/EB family member 2 2 2
MIRT556639 LAMC1 laminin subunit gamma 1 2 2
MIRT559127 C11orf57 chromosome 11 open reading frame 57 2 2
MIRT561405 TUBB2A tubulin beta 2A class IIa 2 2
MIRT569677 SEC23B Sec23 homolog B, coat complex II component 2 4
MIRT574660 KLHL15 kelch like family member 15 2 2
MIRT575030 Tecpr2 tectonin beta-propeller repeat containing 2 2 5
MIRT617683 JRKL JRK like 2 2
MIRT618540 SEMA5A semaphorin 5A 2 2
MIRT620805 C1orf27 chromosome 1 open reading frame 27 2 2
MIRT621569 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT622133 SP4 Sp4 transcription factor 2 2
MIRT624913 CTCFL CCCTC-binding factor like 2 2
MIRT625010 PAK4 p21 (RAC1) activated kinase 4 2 2
MIRT626644 ZNF551 zinc finger protein 551 2 2
MIRT626646 ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 2 2
MIRT626672 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT627945 NNT nicotinamide nucleotide transhydrogenase 2 2
MIRT627963 NLK nemo like kinase 2 2
MIRT628767 SRSF7 serine and arginine rich splicing factor 7 2 2
MIRT629261 KDM2B lysine demethylase 2B 2 2
MIRT629422 ADM2 adrenomedullin 2 2 2
MIRT630238 SORD sorbitol dehydrogenase 2 2
MIRT631272 CENPM centromere protein M 2 4
MIRT631793 CLK4 CDC like kinase 4 2 2
MIRT632058 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT632485 RPS15A ribosomal protein S15a 2 2
MIRT632611 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT632708 MTA3 metastasis associated 1 family member 3 2 2
MIRT632815 INO80 INO80 complex subunit 2 2
MIRT635956 PLA2G12A phospholipase A2 group XIIA 2 2
MIRT636152 UBXN2A UBX domain protein 2A 2 2
MIRT636899 C5orf45 MRN complex interacting protein 2 4
MIRT636930 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 2
MIRT637457 ZNF324B zinc finger protein 324B 2 2
MIRT637900 SLC19A3 solute carrier family 19 member 3 2 2
MIRT639826 ZNF638 zinc finger protein 638 2 2
MIRT640445 ERVMER34-1 endogenous retrovirus group MER34 member 1, envelope 2 2
MIRT640681 ARSK arylsulfatase family member K 2 2
MIRT641611 CAPN7 calpain 7 2 2
MIRT641676 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT646786 IL23R interleukin 23 receptor 2 2
MIRT648352 A2ML1 alpha-2-macroglobulin like 1 2 2
MIRT649144 SPATA5 spermatogenesis associated 5 2 2
MIRT649254 TRIM65 tripartite motif containing 65 2 2
MIRT652491 TMEM178B transmembrane protein 178B 2 2
MIRT653308 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT653945 SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 2 2
MIRT654212 RNF19B ring finger protein 19B 2 2
MIRT654839 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT655159 PHF21A PHD finger protein 21A 2 2
MIRT655316 PDCD11 programmed cell death 11 2 2
MIRT655375 PAX3 paired box 3 2 2
MIRT657301 HOXB5 homeobox B5 2 2
MIRT657593 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT658460 FAM117B family with sequence similarity 117 member B 2 2
MIRT658716 ELOVL4 ELOVL fatty acid elongase 4 2 2
MIRT661640 UGT2B28 UDP glucuronosyltransferase family 2 member B28 2 2
MIRT661712 MTO1 mitochondrial tRNA translation optimization 1 2 4
MIRT661833 ZNF793 zinc finger protein 793 2 2
MIRT663805 BET1L Bet1 golgi vesicular membrane trafficking protein like 2 2
MIRT663884 CXorf56 chromosome X open reading frame 56 2 2
MIRT664672 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 2
MIRT665814 TMEM168 transmembrane protein 168 2 2
MIRT668159 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT668430 FAM20B FAM20B, glycosaminoglycan xylosylkinase 2 2
MIRT672306 GP2 glycoprotein 2 2 2
MIRT673101 SYNPO2L synaptopodin 2 like 2 2
MIRT673437 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT673584 KDELC2 KDEL motif containing 2 2 2
MIRT673718 SLU7 SLU7 homolog, splicing factor 2 2
MIRT673777 MRPL17 mitochondrial ribosomal protein L17 2 2
MIRT674316 IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2 2
MIRT674820 FAM229B family with sequence similarity 229 member B 2 2
MIRT675179 BPTF bromodomain PHD finger transcription factor 2 2
MIRT675586 WWC1 WW and C2 domain containing 1 2 2
MIRT675812 MED28 mediator complex subunit 28 2 2
MIRT677632 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2 2
MIRT683914 PSMB9 proteasome subunit beta 9 2 2
MIRT687135 QPCTL glutaminyl-peptide cyclotransferase like 2 2
MIRT691973 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 2 2
MIRT693078 AS3MT arsenite methyltransferase 2 2
MIRT694084 RNASEH2B ribonuclease H2 subunit B 2 2
MIRT696292 IER3IP1 immediate early response 3 interacting protein 1 2 2
MIRT696541 C3 complement C3 2 2
MIRT701955 MITF melanogenesis associated transcription factor 2 2
MIRT703276 GNG12 G protein subunit gamma 12 2 2
MIRT706852 DNAJB13 DnaJ heat shock protein family (Hsp40) member B13 2 2
MIRT706993 XPO5 exportin 5 2 2
MIRT710716 KRTAP6-1 keratin associated protein 6-1 2 2
MIRT711305 ACOX1 acyl-CoA oxidase 1 2 2
MIRT711514 ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 2 2
MIRT711648 LIPG lipase G, endothelial type 2 2
MIRT711772 CCDC59 coiled-coil domain containing 59 2 2
MIRT714280 COQ7 coenzyme Q7, hydroxylase 2 2
MIRT715048 PRPF38A pre-mRNA processing factor 38A 2 2
MIRT716934 INCENP inner centromere protein 2 2
MIRT717220 OTUD3 OTU deubiquitinase 3 2 2
MIRT717865 BICD2 BICD cargo adaptor 2 2 2
MIRT718836 SNX20 sorting nexin 20 2 2
MIRT720243 GPBP1 GC-rich promoter binding protein 1 2 2
MIRT721969 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT724000 LMTK2 lemur tyrosine kinase 2 2 2
MIRT725193 SDAD1 SDA1 domain containing 1 2 2
MIRT731669 CBL Cbl proto-oncogene 3 1
MIRT732776 AQP4 aquaporin 4 3 0
MIRT733158 ITGA5 integrin subunit alpha 5 1 0
MIRT735623 TLR4 toll like receptor 4 4 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-216a Curcumin NULL 969516 Quantitative real-time PCR Y79 RB cells. 22510010 2012 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-216a Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-216a-5p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3, 2008, OVCAR10, OVCAR3, HeLa, MCF7, MDA-MB-468)
hsa-miR-216a-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-216a-5p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-216a-5p Doxorubicin 31703 NSC123127 approved sensitive High Small Cell Lung Cancer cell line (NCI-H69)
hsa-miR-216a-5p Sorafenib 216239 NSC747971 approved resistant Low Hepatocellular Carcinoma tissue and cell line (HepG2, Hep3B, Huh-7, PLC/PRF/5, HCCLM3, Bel-7404, HLE, SK-HEP-1, SNU-449)
hsa-miR-216a-5p Fluorouracil 3385 NSC19893 approved resistant High Colorectal Cancer tissue
hsa-miR-216a-5p Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer tissue
hsa-miR-216a-5p Sorafenib 216239 NSC747971 approved resistant High Hepatocellular Carcinoma cell line (Huh-7)
hsa-miR-216a-5p Doxorubicin 31703 NSC123127 approved resistant Low Small Cell Lung Cancer cell line (H69, H446)
hsa-miR-216a-5p Cisplatin 5460033 NSC119875 approved resistant Low Ovarian Cancer cell line (SKOV3, OVCA433)
hsa-miR-216a-5p Oxaliplatin 6857599 NSC266046 approved resistant Low Gastric Cancer cell line (MGC, SGC)
hsa-miR-216a-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-216a-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-216a-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-216a-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-216a-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM11)
hsa-miR-216a-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-216a-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-216a-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM43)
hsa-miR-216a-5p Exemestane 60198 NSC713563 approved sensitive cell line (MCF-7)
hsa-miR-216a-5p Testosterone+Tamoxifen sensitive cell line (MCF-7)
hsa-miR-216a-5p Cisplatin 5460033 NSC119875 approved resistant cell line (RPMI2650)
hsa-miR-216a-5p Tamoxifen 2733525 NSC180973 approved sensitive cell line (TamR8)
hsa-miR-216a-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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