miRTarBase - #MIRT629737


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pre-miRNA Information
pre-miRNA hsa-mir-1273h   
Genomic Coordinates chr16: 24203116 - 24203231
Description Homo sapiens miR-1273h stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-1273h-5p
Sequence 33| CUGGGAGGUCAAGGCUGCAGU |53
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1028034199 14 dbSNP
rs542383563 18 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SCD5   
Synonyms ACOD4, FADS4, HSCD5, SCD2, SCD4
Description stearoyl-CoA desaturase 5
Transcript NM_001037582   
Other Transcripts NM_024906   
Expression
Putative miRNA Targets on SCD5
3'UTR of SCD5
(miRNA target sites are highlighted)		 
>SCD5|NM_001037582|3'UTR
   1 ACTTGGAACAGCCATCCCACATGTCTGCCGTTGCAACCTCGGTTCATGGCTTTGGTTACAATAGCTCTCTTGTACATTGG
  81 ATCGTGGGAGGGGGCAGAGGGTGGGGAAGGAACGAGTCAATGTGGTTTGGGAATGTTTTTGTTTATCTCAAAATAATGTT
 161 GAAATACAATTATCAATGAAAAAACTTTCGTTTTTTTTTTTGTTTGTTTTGTTTTTGAGACAGAGTCTCACTCTGTCACC
 241 CAGGCTGGAGTGCAGTGGCGCAGTCTCGGCTCACTGCAGCCTCCACCTACCTGGTTCAAGCAATTCTCCTGCCTCAGCCT
 321 CCTGAGTAGCTGAGATTACAGGAGCCTGCCACCACACCCAGCTAATTTTTTTGTATTTTTAGTAGAGACAGGGTTTCATC
 401 ATGTTGGCCAGACTGGCCTCGAATTCCTGACCTCAGGCAATCCACCCGCCTCGGCCTCCCAAAGAGCTGGGATTACAGGC
 481 GTGAGCCACCGCACCCTGCCGAAAAAAACTTTTTTTTTTTTGAGACGGAGGCTCGCTCTGTCCCCCAGGCTGGAGTGCAG
 561 TGGCGAGATCTCAGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGA
 641 GCCAGCGCGCCCAGCCTAAAAAACTTTTCAAGTCAATATTACTACGATTTAACATTAGAGTGTGGACATGTGATTTAATC
 721 GCTATAGCTAAAATACGTCAAATATACGTTGTCATGTGCTTGAACATGATGCTAACCCTGACAGGATGAAGGAAAGTAAT
 801 ATTCTTTCAGTGTAGTTCAGGAGAGCATTTGTTTTCTTTTCTACCAATTAACCCATCATTGCTTTTAAACAACCATCTGA
 881 AGGAGCAGAGAGGCAGGGTAGAAGACAGAAGGGGGATCTATGTGGTAACTAAAGAATGTTTCTGTTTTGTTAATTATTGT
 961 GTGTGTGTGGTTTTATTGTTTGCTTAAGAGAATCAAAAACTGAAAAAAATGAGAATACAGGAAATGGCTCTTGTTTATTT
1041 TTTTGCTGTGTTTACAGCTTGTTAATGCTCTACTGTCTTTGTTTCAAGAGAGATTTGTTCACTGCCCAGCTCGTTTTGTG
1121 TCCTGAGCCCTATGGCCAGCCCACCTTATAAATCATGCCTGTTTAGATGTTTGATTTTGTTCTGTTTGCTATTGTTATCT
1201 TAAAGGTGTATAACTCTGACATGCCAGACATCAAATTAAGCTCAAATTAAGCTCTCGTTTAAATGTTTAAGCACCTAATT
1281 TATATTCTAATTGATCCCAGCCACTGATGCATGTACTTTAGCTACTTCTGCTAAATAAGCATATTAATTTTCCACATCAG
1361 ACCATCAGATCTTGAGAACCAACAGTTATCTAGAATTCCGTGTCTACTAATGTTTCACCTGCATGCAGCCTTCATTAATT
1441 TTGTAGCAAAATATAAAGTGATCATTATGTAGCTTCTGGATTAAAAAAATTTGTGTGTGAAGTTGCTTTGTAAAGTGCAT
1521 GTGGAATTAATGGGACAGTGTGCCCTTTGTGTTAGATGTTAGAGCAAAAGAAAGGGCTTATAGTGTTAGTATTGGAGCAC
1601 TTTGAAGATAGATATTTTCAGAAAAGATGTAGGATTTAAAAGTTAAATTTTAAATTTTAGAAAAAGATATGATGGCAATT
1681 GGAAATAGTCACAATGAAGTTCTTCATCCAGTAGGTGTTTAACAGTGTTATTTTGCCACTGGTAATGTGTAAACTGTGAG
1761 TGATTTACAATAAATGATTATGAATTCATTAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugacGUCGGAACUGGAGGGUc 5'
              | |||| |:||||||| 
Target 5' ccacCCGCCTCGGCCTCCCAa 3'
 442 - 462 165.00 -21.60
2 
miRNA  3' ugACGUCGGAACUGGAGGGUc 5'
            ||||  ||  :||||||: 
Target 5' acTGCAAGCTCCGCCTCCCGg 3'
 578 - 598 143.00 -25.20
3 
miRNA  3' ugACGUCGGAACUGGAGGGUc 5'
            | | ||||  :||||||: 
Target 5' tcTCCTGCCTCAGCCTCCCGa 3'
 610 - 630 143.00 -20.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30464992 17 COSMIC
COSN30179254 20 COSMIC
COSN21487932 29 COSMIC
COSN31559156 44 COSMIC
COSN20050972 45 COSMIC
COSN30512100 49 COSMIC
COSN24309935 69 COSMIC
COSN31531267 106 COSMIC
COSN28682351 116 COSMIC
COSN32056931 131 COSMIC
COSN25707917 471 COSMIC
COSN20100273 604 COSMIC
COSN20962360 629 COSMIC
COSN26189052 721 COSMIC
COSN26624443 891 COSMIC
COSN22490829 1111 COSMIC
COSN9243467 1257 COSMIC
COSN5578936 1565 COSMIC
COSN21528538 1605 COSMIC
COSN32058553 1720 COSMIC
rs28476539 189 GWAS
rs553093210 201 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1057474842 6 dbSNP
rs377339242 11 dbSNP
rs747661862 13 dbSNP
rs1372813002 14 dbSNP
rs778475606 20 dbSNP
rs190553289 21 dbSNP
rs369292537 22 dbSNP
rs780011012 24 dbSNP
rs1255866155 29 dbSNP
rs748435446 30 dbSNP
rs1273580627 33 dbSNP
rs1484019138 37 dbSNP
rs115285025 40 dbSNP
rs750709969 41 dbSNP
rs778075280 42 dbSNP
rs767888178 46 dbSNP
rs1212576731 47 dbSNP
rs1269968917 50 dbSNP
rs114652507 58 dbSNP
rs1156637039 60 dbSNP
rs1047858199 62 dbSNP
rs1441317149 63 dbSNP
rs1451866865 67 dbSNP
rs75516791 68 dbSNP
rs1448136728 73 dbSNP
rs1184282454 77 dbSNP
rs1396062171 80 dbSNP
rs547988385 83 dbSNP
rs1171013159 84 dbSNP
rs943239645 87 dbSNP
rs1401391231 90 dbSNP
rs531368075 90 dbSNP
rs910394915 91 dbSNP
rs1046227539 92 dbSNP
rs948721699 93 dbSNP
rs1296685356 105 dbSNP
rs201488721 109 dbSNP
rs145936629 110 dbSNP
rs542423158 113 dbSNP
rs774985823 114 dbSNP
rs72658996 116 dbSNP
rs977317374 120 dbSNP
rs1358009044 122 dbSNP
rs1265729063 126 dbSNP
rs1244794757 134 dbSNP
rs1254070530 145 dbSNP
rs532313878 172 dbSNP
rs922400288 176 dbSNP
rs1015853294 179 dbSNP
rs1470601813 185 dbSNP
rs975120064 188 dbSNP
rs28476539 189 dbSNP
rs540574122 190 dbSNP
rs1388333742 191 dbSNP
rs71305572 191 dbSNP
rs1406945075 192 dbSNP
rs574752810 192 dbSNP
rs1239307111 196 dbSNP
rs1006430162 198 dbSNP
rs879123578 199 dbSNP
rs1424292404 200 dbSNP
rs952294937 201 dbSNP
rs1208445188 202 dbSNP
rs139259208 202 dbSNP
rs1438678114 202 dbSNP
rs1491026910 202 dbSNP
rs35490627 202 dbSNP
rs553093210 202 dbSNP
rs1459331256 204 dbSNP
rs1291631836 206 dbSNP
rs1170612438 210 dbSNP
rs1391660593 210 dbSNP
rs1476012531 211 dbSNP
rs1242101354 212 dbSNP
rs1191475929 217 dbSNP
rs758746139 226 dbSNP
rs866703251 241 dbSNP
rs1243249659 245 dbSNP
rs1221213351 250 dbSNP
rs1340471747 251 dbSNP
rs561402024 255 dbSNP
rs566012442 256 dbSNP
rs907344086 259 dbSNP
rs1011646761 260 dbSNP
rs758987370 267 dbSNP
rs1012984416 268 dbSNP
rs1162566363 273 dbSNP
rs748617232 280 dbSNP
rs185748411 285 dbSNP
rs1268281352 288 dbSNP
rs1368320594 306 dbSNP
rs1408778352 313 dbSNP
rs1039694306 317 dbSNP
rs1380700673 323 dbSNP
rs1331426244 325 dbSNP
rs1394840973 326 dbSNP
rs1302347580 329 dbSNP
rs1404539509 333 dbSNP
rs894485092 337 dbSNP
rs752067599 341 dbSNP
rs1309915305 343 dbSNP
rs1410667105 347 dbSNP
rs1418897640 349 dbSNP
rs779452468 352 dbSNP
rs575886897 354 dbSNP
rs559227118 356 dbSNP
rs1199196385 360 dbSNP
rs1489712661 364 dbSNP
rs1272844715 367 dbSNP
rs755365709 368 dbSNP
rs903140819 372 dbSNP
rs1042008529 387 dbSNP
rs933868606 393 dbSNP
rs922399708 398 dbSNP
rs1181306430 403 dbSNP
rs1255428219 403 dbSNP
rs1436667225 414 dbSNP
rs1270304426 421 dbSNP
rs1220838043 429 dbSNP
rs995332467 430 dbSNP
rs754169036 440 dbSNP
rs897821721 444 dbSNP
rs1282377009 447 dbSNP
rs1190290850 448 dbSNP
rs1388077448 450 dbSNP
rs1428780973 452 dbSNP
rs539329081 453 dbSNP
rs1360436241 459 dbSNP
rs1464122288 461 dbSNP
rs1343866195 466 dbSNP
rs942413748 467 dbSNP
rs909558864 476 dbSNP
rs983784345 478 dbSNP
rs1295954108 479 dbSNP
rs1443220443 480 dbSNP
rs766693442 481 dbSNP
rs573623538 483 dbSNP
rs1326967570 486 dbSNP
rs971800679 490 dbSNP
rs963063438 491 dbSNP
rs1036802008 493 dbSNP
rs1407546744 495 dbSNP
rs1261327950 497 dbSNP
rs1465335565 500 dbSNP
rs376769627 503 dbSNP
rs1246006524 506 dbSNP
rs1448620693 508 dbSNP
rs553391835 511 dbSNP
rs1431024171 512 dbSNP
rs1174755925 518 dbSNP
rs1345252634 522 dbSNP
rs1392986712 522 dbSNP
rs1459325464 522 dbSNP
rs763398348 522 dbSNP
rs1479623776 527 dbSNP
rs1414674326 531 dbSNP
rs972710393 532 dbSNP
rs971599998 534 dbSNP
rs533741794 535 dbSNP
rs1211685956 537 dbSNP
rs1461699529 543 dbSNP
rs1013015538 544 dbSNP
rs894599683 546 dbSNP
rs1262502961 547 dbSNP
rs62311446 552 dbSNP
rs1248176718 554 dbSNP
rs1487331989 563 dbSNP
rs1201693294 566 dbSNP
rs28483107 570 dbSNP
rs11943634 582 dbSNP
rs547023516 589 dbSNP
rs903170889 594 dbSNP
rs1041649285 597 dbSNP
rs1326014876 603 dbSNP
rs1277830935 604 dbSNP
rs760101058 604 dbSNP
rs34428564 605 dbSNP
rs537576272 605 dbSNP
rs771720182 605 dbSNP
rs893188196 607 dbSNP
rs745733778 612 dbSNP
rs568023769 613 dbSNP
rs1408110979 615 dbSNP
rs1287730169 616 dbSNP
rs1328406517 621 dbSNP
rs568702753 629 dbSNP
rs1291838817 641 dbSNP
rs1220497736 646 dbSNP
rs1252132666 647 dbSNP
rs1039477630 648 dbSNP
rs1336584353 649 dbSNP
rs1179411755 650 dbSNP
rs113631458 651 dbSNP
rs200585894 651 dbSNP
rs1391243176 667 dbSNP
rs942528220 670 dbSNP
rs1241092388 672 dbSNP
rs909673377 674 dbSNP
rs552002366 676 dbSNP
rs1169575204 678 dbSNP
rs1372646574 685 dbSNP
rs532178920 686 dbSNP
rs1405420354 694 dbSNP
rs1183087801 701 dbSNP
rs983815515 703 dbSNP
rs1307556610 708 dbSNP
rs929684800 721 dbSNP
rs1444637928 723 dbSNP
rs918215864 724 dbSNP
rs1285911886 729 dbSNP
rs1376839862 730 dbSNP
rs1227540182 733 dbSNP
rs1052098805 734 dbSNP
rs972347822 736 dbSNP
rs1202582388 741 dbSNP
rs1466222239 745 dbSNP
rs1273338075 746 dbSNP
rs1261060335 748 dbSNP
rs972024214 749 dbSNP
rs933223868 754 dbSNP
rs1188962952 771 dbSNP
rs566719462 777 dbSNP
rs375206102 781 dbSNP
rs184058425 783 dbSNP
rs1316551393 789 dbSNP
rs1472718114 792 dbSNP
rs1189622807 793 dbSNP
rs991696733 797 dbSNP
rs1392398733 798 dbSNP
rs958843966 801 dbSNP
rs1282342402 809 dbSNP
rs547719766 816 dbSNP
rs1360196906 817 dbSNP
rs1416277156 819 dbSNP
rs376701470 821 dbSNP
rs1332203558 825 dbSNP
rs1314501635 827 dbSNP
rs1357375923 838 dbSNP
rs561155198 845 dbSNP
rs1451061521 847 dbSNP
rs1327525401 858 dbSNP
rs1298154250 865 dbSNP
rs903202902 885 dbSNP
rs1020665303 888 dbSNP
rs1367055593 898 dbSNP
rs1225788219 900 dbSNP
rs544679076 905 dbSNP
rs941821654 910 dbSNP
rs531064978 911 dbSNP
rs767581194 916 dbSNP
rs535024375 917 dbSNP
rs1289807272 918 dbSNP
rs991196908 921 dbSNP
rs565474480 925 dbSNP
rs1343805664 942 dbSNP
rs1250330756 944 dbSNP
rs140708601 952 dbSNP
rs1188287944 959 dbSNP
rs1424924139 966 dbSNP
rs1384032601 967 dbSNP
rs1479098238 968 dbSNP
rs928299332 970 dbSNP
rs1469265461 975 dbSNP
rs1161174189 977 dbSNP
rs1039592729 989 dbSNP
rs967623358 991 dbSNP
rs1451230718 1003 dbSNP
rs1020468602 1015 dbSNP
rs1185863768 1017 dbSNP
rs1317290568 1033 dbSNP
rs1331340602 1036 dbSNP
rs990315415 1037 dbSNP
rs1248266859 1045 dbSNP
rs1272637890 1045 dbSNP
rs957476564 1047 dbSNP
rs1270614462 1049 dbSNP
rs1463885439 1057 dbSNP
rs1006701145 1060 dbSNP
rs1360492287 1066 dbSNP
rs1453609390 1071 dbSNP
rs545568682 1072 dbSNP
rs1246250742 1080 dbSNP
rs75286236 1081 dbSNP
rs929690010 1084 dbSNP
rs1161410965 1090 dbSNP
rs918268978 1102 dbSNP
rs553595118 1106 dbSNP
rs1046523445 1107 dbSNP
rs1309782941 1109 dbSNP
rs542973643 1112 dbSNP
rs3733230 1135 dbSNP
rs991729201 1146 dbSNP
rs1360247287 1149 dbSNP
rs554302064 1152 dbSNP
rs1289619569 1156 dbSNP
rs191818672 1157 dbSNP
rs763923910 1164 dbSNP
rs749152300 1177 dbSNP
rs762725806 1177 dbSNP
rs568567515 1178 dbSNP
rs997844981 1179 dbSNP
rs558240307 1191 dbSNP
rs1266978468 1195 dbSNP
rs1483466434 1197 dbSNP
rs1036184959 1199 dbSNP
rs1249695171 1225 dbSNP
rs1471605591 1229 dbSNP
rs1180958071 1232 dbSNP
rs1300731120 1232 dbSNP
rs1463013810 1233 dbSNP
rs372861957 1252 dbSNP
rs1161177636 1255 dbSNP
rs1459266942 1255 dbSNP
rs941854106 1256 dbSNP
rs1368905421 1257 dbSNP
rs887549225 1268 dbSNP
rs538412601 1269 dbSNP
rs3821974 1271 dbSNP
rs1314095705 1276 dbSNP
rs1426692423 1286 dbSNP
rs1342743325 1297 dbSNP
rs546852788 1298 dbSNP
rs1243074183 1299 dbSNP
rs1426967824 1301 dbSNP
rs11552968 1304 dbSNP
rs981093346 1324 dbSNP
rs946322234 1339 dbSNP
rs1482754515 1341 dbSNP
rs913479098 1344 dbSNP
rs1256788217 1355 dbSNP
rs1425428469 1356 dbSNP
rs1065403 1361 dbSNP
rs770526715 1362 dbSNP
rs998631984 1364 dbSNP
rs1449741448 1382 dbSNP
rs1170073496 1399 dbSNP
rs957507908 1400 dbSNP
rs1461073032 1404 dbSNP
rs1302849692 1407 dbSNP
rs1404999159 1410 dbSNP
rs1394787097 1421 dbSNP
rs1314871828 1423 dbSNP
rs569910190 1429 dbSNP
rs201794424 1434 dbSNP
rs965330279 1438 dbSNP
rs985956527 1445 dbSNP
rs1307093426 1453 dbSNP
rs1210932732 1460 dbSNP
rs1251991191 1461 dbSNP
rs1018174034 1467 dbSNP
rs1006730801 1469 dbSNP
rs6840 1473 dbSNP
rs1030115449 1478 dbSNP
rs1306311409 1487 dbSNP
rs1465201158 1490 dbSNP
rs994172631 1490 dbSNP
rs1224571956 1493 dbSNP
rs1048672202 1497 dbSNP
rs1176227258 1500 dbSNP
rs1378856725 1508 dbSNP
rs1014773677 1512 dbSNP
rs1280909233 1517 dbSNP
rs1392794605 1537 dbSNP
rs1437762734 1542 dbSNP
rs1318870654 1549 dbSNP
rs117694935 1556 dbSNP
rs779548226 1557 dbSNP
rs1396539489 1562 dbSNP
rs755085023 1570 dbSNP
rs1220035663 1577 dbSNP
rs1297140718 1581 dbSNP
rs1303554534 1591 dbSNP
rs1310496433 1592 dbSNP
rs1006068600 1595 dbSNP
rs752016320 1598 dbSNP
rs867489731 1609 dbSNP
rs1329706015 1610 dbSNP
rs887626765 1611 dbSNP
rs1408280830 1614 dbSNP
rs1240129036 1625 dbSNP
rs994009561 1632 dbSNP
rs1176874364 1651 dbSNP
rs896938218 1653 dbSNP
rs1479947407 1656 dbSNP
rs1046130901 1663 dbSNP
rs1479180512 1668 dbSNP
rs949062746 1670 dbSNP
rs1157495512 1671 dbSNP
rs1426963649 1671 dbSNP
rs916221545 1673 dbSNP
rs1056077577 1678 dbSNP
rs937538273 1679 dbSNP
rs1295528339 1681 dbSNP
rs926150691 1685 dbSNP
rs1404418442 1686 dbSNP
rs979373091 1688 dbSNP
rs540657144 1699 dbSNP
rs766920300 1712 dbSNP
rs1479937084 1717 dbSNP
rs1265615913 1721 dbSNP
rs945682895 1724 dbSNP
rs1266871082 1741 dbSNP
rs1323212346 1742 dbSNP
rs1489680571 1744 dbSNP
rs967567832 1747 dbSNP
rs1251908236 1764 dbSNP
rs1473883207 1767 dbSNP
rs913510226 1769 dbSNP
rs1261693797 1781 dbSNP
rs1407831865 1782 dbSNP
rs1406349991 1783 dbSNP
rs755459751 1787 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084044. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep3 HITS-CLIP data was present in GSM1084045. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep3 HITS-CLIP data was present in GSM1084046. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep4 HITS-CLIP data was present in GSM1084047. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep4 HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084068. RNA binding protein: AGO2. Condition:CLIP_noemetine_SigmaAb HITS-CLIP data was present in GSM1084072. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084076. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084044
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep3
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUACAGGCGUGAGCCACC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084045
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep3
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUACAGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084046
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep4
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUACAGGCGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1084047
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep4
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUACAGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUACAGGCGUGAGCCACC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1084068
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SigmaAb
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUACAGGCGUGAGCCAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1084072
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_AbnovaAb
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUACAGGCGUGAGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM1084073
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_AbnovaAb
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUACAGGCGUGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 10 for dataset GSM1084076
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_SigmaAb
Location of target site ENST00000319540.4 | 3UTR | CAAAGAGCUGGGAUUACAGGCGUGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
494 hsa-miR-1273h-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT074355 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT100721 TJAP1 tight junction associated protein 1 2 2
MIRT115545 MAZ MYC associated zinc finger protein 2 2
MIRT124982 XIAP X-linked inhibitor of apoptosis 2 4
MIRT139911 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT177183 ARL5B ADP ribosylation factor like GTPase 5B 2 4
MIRT187994 MBD6 methyl-CpG binding domain protein 6 2 2
MIRT207410 MAT2A methionine adenosyltransferase 2A 2 6
MIRT241928 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT260110 KLHL21 kelch like family member 21 2 2
MIRT260358 XRCC6 X-ray repair cross complementing 6 2 6
MIRT266428 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT294663 ZNF548 zinc finger protein 548 2 2
MIRT351039 PLEKHB2 pleckstrin homology domain containing B2 2 2
MIRT379943 PRRG4 proline rich and Gla domain 4 2 2
MIRT398983 KAT7 lysine acetyltransferase 7 2 2
MIRT441465 BEST3 bestrophin 3 2 2
MIRT446750 ZNF491 zinc finger protein 491 2 2
MIRT449224 RAD51B RAD51 paralog B 2 2
MIRT450623 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT451090 ZNF584 zinc finger protein 584 2 2
MIRT451558 CIAPIN1 cytokine induced apoptosis inhibitor 1 2 2
MIRT451736 CES3 carboxylesterase 3 2 2
MIRT452411 QDPR quinoid dihydropteridine reductase 2 2
MIRT452559 ZFP69B ZFP69 zinc finger protein B 2 2
MIRT452851 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT452922 DISC1 disrupted in schizophrenia 1 2 2
MIRT453043 TANGO2 transport and golgi organization 2 homolog 2 4
MIRT453097 HOXC4 homeobox C4 2 2
MIRT453297 ZNF394 zinc finger protein 394 2 2
MIRT453593 ZNF557 zinc finger protein 557 2 2
MIRT453787 KBTBD12 kelch repeat and BTB domain containing 12 2 2
MIRT453987 CECR1 adenosine deaminase 2 2 2
MIRT454083 TMEM209 transmembrane protein 209 2 2
MIRT454652 FBXL18 F-box and leucine rich repeat protein 18 2 2
MIRT454753 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2 2
MIRT455311 TTLL9 tubulin tyrosine ligase like 9 2 2
MIRT456468 SERAC1 serine active site containing 1 2 2
MIRT456554 TOMM20 translocase of outer mitochondrial membrane 20 2 2
MIRT456716 TMEM239 transmembrane protein 239 2 4
MIRT456796 SIGLEC14 sialic acid binding Ig like lectin 14 2 2
MIRT457487 SLC35F6 solute carrier family 35 member F6 2 2
MIRT457999 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT458130 TLCD2 TLC domain containing 2 2 2
MIRT459027 ZNF490 zinc finger protein 490 2 4
MIRT459119 FADS6 fatty acid desaturase 6 2 2
MIRT459315 HAVCR2 hepatitis A virus cellular receptor 2 2 2
MIRT459385 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT459412 FAM83B family with sequence similarity 83 member B 2 2
MIRT459974 RFT1 RFT1 homolog 2 2
MIRT460480 FAM105A family with sequence similarity 105 member A 2 6
MIRT460586 FEM1A fem-1 homolog A 2 2
MIRT460920 NOA1 nitric oxide associated 1 2 4
MIRT461072 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT461590 DPH2 DPH2 homolog 2 2
MIRT461854 ZNF317 zinc finger protein 317 2 2
MIRT462176 ACADL acyl-CoA dehydrogenase, long chain 2 2
MIRT462446 GCDH glutaryl-CoA dehydrogenase 2 2
MIRT463854 WNT7B Wnt family member 7B 2 2
MIRT464310 UST uronyl 2-sulfotransferase 2 2
MIRT464815 UBE2B ubiquitin conjugating enzyme E2 B 2 2
MIRT465453 TOR2A torsin family 2 member A 2 2
MIRT466073 TMEM184C transmembrane protein 184C 2 2
MIRT466514 TBXA2R thromboxane A2 receptor 2 2
MIRT467072 SRRD SRR1 domain containing 2 2
MIRT469551 RARA retinoic acid receptor alpha 2 2
MIRT469741 RAB2B RAB2B, member RAS oncogene family 2 2
MIRT470759 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT470875 PLXND1 plexin D1 2 2
MIRT470976 PITPNA phosphatidylinositol transfer protein alpha 2 2
MIRT471048 PIM3 Pim-3 proto-oncogene, serine/threonine kinase 2 2
MIRT471215 PHAX phosphorylated adaptor for RNA export 2 2
MIRT471246 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT471286 PGAM4 phosphoglycerate mutase family member 4 2 2
MIRT471467 PDE7B phosphodiesterase 7B 2 2
MIRT473069 MORN4 MORN repeat containing 4 2 4
MIRT473989 LRRC20 leucine rich repeat containing 20 2 2
MIRT474518 KLHDC8A kelch domain containing 8A 2 2
MIRT474990 KANSL1 KAT8 regulatory NSL complex subunit 1 2 2
MIRT475547 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 2 2
MIRT476350 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT477298 EPHB2 EPH receptor B2 2 2
MIRT477933 DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory 2 2
MIRT478282 DDX19A DEAD-box helicase 19A 2 4
MIRT478472 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT478559 CTNND1 catenin delta 1 2 2
MIRT478618 CTDNEP1 CTD nuclear envelope phosphatase 1 2 2
MIRT478834 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT479007 COL5A1 collagen type V alpha 1 chain 2 2
MIRT479166 CLSPN claspin 2 2
MIRT482454 ADAR adenosine deaminase, RNA specific 2 4
MIRT483019 KHSRP KH-type splicing regulatory protein 2 4
MIRT483798 CYP2W1 cytochrome P450 family 2 subfamily W member 1 2 6
MIRT486087 SLC7A5 solute carrier family 7 member 5 2 4
MIRT486304 SIPA1 signal-induced proliferation-associated 1 2 2
MIRT486490 MYH11 myosin heavy chain 11 2 2
MIRT486881 TSPYL4 TSPY like 4 2 2
MIRT487125 NCOR2 nuclear receptor corepressor 2 2 2
MIRT487542 TM6SF2 transmembrane 6 superfamily member 2 2 4
MIRT487676 B3GALT5 beta-1,3-galactosyltransferase 5 2 4
MIRT489251 TTLL1 tubulin tyrosine ligase like 1 2 4
MIRT489276 RBM8A RNA binding motif protein 8A 2 8
MIRT489496 CRLF3 cytokine receptor like factor 3 2 4
MIRT489571 SSBP2 single stranded DNA binding protein 2 2 2
MIRT489694 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT490166 TMEM63C transmembrane protein 63C 2 2
MIRT491199 MLLT1 MLLT1, super elongation complex subunit 2 4
MIRT491260 DHX40 DEAH-box helicase 40 2 2
MIRT491385 HAUS3 HAUS augmin like complex subunit 3 2 2
MIRT491548 YAE1D1 Yae1 domain containing 1 2 2
MIRT492722 PHF12 PHD finger protein 12 2 2
MIRT493866 FAM73B mitoguardin 2 2 4
MIRT494549 BAK1 BCL2 antagonist/killer 1 2 2
MIRT498586 KRT8 keratin 8 2 2
MIRT498722 SNTN sentan, cilia apical structure protein 2 6
MIRT499982 HIST1H2BD histone cluster 1 H2B family member d 2 4
MIRT503414 SLC25A45 solute carrier family 25 member 45 2 6
MIRT508491 FTO FTO, alpha-ketoglutarate dependent dioxygenase 2 2
MIRT508877 METTL14 methyltransferase like 14 2 2
MIRT509622 RRP7A ribosomal RNA processing 7 homolog A 2 4
MIRT510104 IRAK3 interleukin 1 receptor associated kinase 3 2 8
MIRT510139 PDGFRA platelet derived growth factor receptor alpha 2 4
MIRT510353 ZNF703 zinc finger protein 703 2 6
MIRT510620 TMEM167A transmembrane protein 167A 2 4
MIRT510786 SF3B3 splicing factor 3b subunit 3 2 6
MIRT511021 NRF1 nuclear respiratory factor 1 2 2
MIRT513925 GHITM growth hormone inducible transmembrane protein 2 2
MIRT514342 DNAH17 dynein axonemal heavy chain 17 2 4
MIRT515015 SUMF2 sulfatase modifying factor 2 2 2
MIRT515246 DUSP28 dual specificity phosphatase 28 2 2
MIRT516202 RPP30 ribonuclease P/MRP subunit p30 2 2
MIRT516435 ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 2 4
MIRT516666 ZNF860 zinc finger protein 860 2 4
MIRT518373 ZNF250 zinc finger protein 250 2 2
MIRT518930 LSG1 large 60S subunit nuclear export GTPase 1 2 2
MIRT519676 ZNF70 zinc finger protein 70 2 2
MIRT519902 ZFAND4 zinc finger AN1-type containing 4 2 4
MIRT519945 ZCCHC8 zinc finger CCHC-type containing 8 2 2
MIRT520321 UBXN2A UBX domain protein 2A 2 2
MIRT520606 TMEM41B transmembrane protein 41B 2 2
MIRT520663 TMEM11 transmembrane protein 11 2 2
MIRT520852 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT521443 RAD51 RAD51 recombinase 2 2
MIRT521671 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 2
MIRT522281 NKAP NFKB activating protein 2 2
MIRT522333 NCKIPSD NCK interacting protein with SH3 domain 2 8
MIRT522535 MED28 mediator complex subunit 28 2 6
MIRT523478 GNG4 G protein subunit gamma 4 2 2
MIRT523672 FOPNL FGFR1OP N-terminal like 2 2
MIRT523715 FBXW2 F-box and WD repeat domain containing 2 2 4
MIRT523867 ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 2 4
MIRT524043 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT524167 DFFA DNA fragmentation factor subunit alpha 2 2
MIRT524928 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT526825 PHC1 polyhomeotic homolog 1 2 2
MIRT531017 TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3 2 2
MIRT536085 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT540681 BMP3 bone morphogenetic protein 3 2 2
MIRT541708 TMEM33 transmembrane protein 33 2 2
MIRT541755 KLF8 Kruppel like factor 8 2 2
MIRT541888 LY6G5B lymphocyte antigen 6 family member G5B 2 2
MIRT545714 SPTLC2 serine palmitoyltransferase long chain base subunit 2 2 2
MIRT559054 C19orf47 chromosome 19 open reading frame 47 2 4
MIRT561748 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT562365 ETV3 ETS variant 3 2 2
MIRT562821 GCFC2 GC-rich sequence DNA-binding factor 2 2 2
MIRT562900 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT564452 SLC35E2 solute carrier family 35 member E2 2 5
MIRT569111 ONECUT3 one cut homeobox 3 2 2
MIRT569224 SUSD1 sushi domain containing 1 2 2
MIRT570271 ARPC3 actin related protein 2/3 complex subunit 3 2 2
MIRT570498 TFIP11 tuftelin interacting protein 11 2 2
MIRT570844 GPRC5C G protein-coupled receptor class C group 5 member C 2 2
MIRT571311 TPCN2 two pore segment channel 2 2 2
MIRT572077 EXOC8 exocyst complex component 8 2 2
MIRT572116 DNAJC24 DnaJ heat shock protein family (Hsp40) member C24 2 2
MIRT573054 TRIB1 tribbles pseudokinase 1 2 2
MIRT573483 IQSEC3 IQ motif and Sec7 domain 3 2 2
MIRT573656 HES6 hes family bHLH transcription factor 6 2 2
MIRT574343 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT576494 Slc35e2 solute carrier family 35, member E2 2 4
MIRT608033 UBLCP1 ubiquitin like domain containing CTD phosphatase 1 2 2
MIRT611326 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT613660 KIAA1210 KIAA1210 2 2
MIRT615638 ATF6 activating transcription factor 6 2 2
MIRT618573 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT618865 MBL2 mannose binding lectin 2 2 2
MIRT618962 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT619172 SLC16A4 solute carrier family 16 member 4 2 2
MIRT620298 AQP6 aquaporin 6 2 2
MIRT620683 RFTN2 raftlin family member 2 2 2
MIRT621637 UBXN2B UBX domain protein 2B 2 2
MIRT621993 STK4 serine/threonine kinase 4 2 2
MIRT622421 NUDT19 nudix hydrolase 19 2 2
MIRT622804 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 4
MIRT624786 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 2
MIRT624968 ZNF665 zinc finger protein 665 2 4
MIRT625479 SMAD9 SMAD family member 9 2 2
MIRT626594 ACAA2 acetyl-CoA acyltransferase 2 2 4
MIRT626708 TRIM65 tripartite motif containing 65 2 2
MIRT626975 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT627489 STRIP2 striatin interacting protein 2 2 2
MIRT628505 ZNF878 zinc finger protein 878 2 2
MIRT628533 ZNF701 zinc finger protein 701 2 2
MIRT628591 TMEM251 transmembrane protein 251 2 2
MIRT628818 SLC25A34 solute carrier family 25 member 34 2 2
MIRT628896 IGSF6 immunoglobulin superfamily member 6 2 2
MIRT628958 UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) 2 2
MIRT629005 OSBPL10 oxysterol binding protein like 10 2 2
MIRT629059 KIF1C kinesin family member 1C 2 2
MIRT629192 PAPOLA poly(A) polymerase alpha 2 2
MIRT629346 TMPRSS11BNL TMPRSS11B N-terminal like, pseudogene 2 2
MIRT629447 WIZ widely interspaced zinc finger motifs 2 2
MIRT629696 XKR4 XK related 4 2 2
MIRT629737 SCD5 stearoyl-CoA desaturase 5 2 2
MIRT629896 SPATA5 spermatogenesis associated 5 2 2
MIRT629953 GLP2R glucagon like peptide 2 receptor 2 2
MIRT630023 MTL5 testis expressed metallothionein like protein 2 2
MIRT630181 TLN1 talin 1 2 2
MIRT630325 PAQR5 progestin and adipoQ receptor family member 5 2 2
MIRT630389 MYH9 myosin heavy chain 9 2 4
MIRT630695 EXTL3 exostosin like glycosyltransferase 3 2 2
MIRT631054 LINC00346 long intergenic non-protein coding RNA 346 2 2
MIRT631130 SYNJ2 synaptojanin 2 2 2
MIRT631374 COL4A3BP collagen type IV alpha 3 binding protein 2 2
MIRT631557 TRAF3IP2 TRAF3 interacting protein 2 2 2
MIRT631615 PCDHB11 protocadherin beta 11 2 2
MIRT631935 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 4
MIRT632109 SSR1 signal sequence receptor subunit 1 2 2
MIRT632168 CCL22 C-C motif chemokine ligand 22 2 2
MIRT632445 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 2
MIRT632652 NAV1 neuron navigator 1 2 2
MIRT632688 MTMR10 myotubularin related protein 10 2 2
MIRT632828 IGF1 insulin like growth factor 1 2 2
MIRT632905 FRRS1 ferric chelate reductase 1 2 2
MIRT633027 DNAL1 dynein axonemal light chain 1 2 2
MIRT633379 FBXW8 F-box and WD repeat domain containing 8 2 2
MIRT633440 KLLN killin, p53-regulated DNA replication inhibitor 2 2
MIRT633726 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT633832 WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 2 2
MIRT633862 ATP6V1A ATPase H+ transporting V1 subunit A 2 2
MIRT634042 NUP155 nucleoporin 155 2 2
MIRT634266 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT634374 RAP2B RAP2B, member of RAS oncogene family 2 2
MIRT634439 PDE7A phosphodiesterase 7A 2 2
MIRT634573 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT634620 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT634693 DSEL dermatan sulfate epimerase-like 2 2
MIRT634768 CD3D CD3d molecule 2 2
MIRT635024 WWTR1 WW domain containing transcription regulator 1 2 2
MIRT635384 NHLRC2 NHL repeat containing 2 2 2
MIRT635577 TTC9C tetratricopeptide repeat domain 9C 2 2
MIRT635793 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT635837 ZNF264 zinc finger protein 264 2 2
MIRT636043 ZSCAN29 zinc finger and SCAN domain containing 29 2 4
MIRT636070 ZNF280C zinc finger protein 280C 2 2
MIRT636697 ARSK arylsulfatase family member K 2 2
MIRT637438 ZNF324B zinc finger protein 324B 2 2
MIRT637582 PLD6 phospholipase D family member 6 2 2
MIRT637672 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D 2 2
MIRT637887 SLC19A3 solute carrier family 19 member 3 2 4
MIRT638353 RBMS2 RNA binding motif single stranded interacting protein 2 2 4
MIRT638597 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT638821 CRTAP cartilage associated protein 2 2
MIRT638871 CEP97 centrosomal protein 97 2 4
MIRT639660 PPEF2 protein phosphatase with EF-hand domain 2 2 4
MIRT640200 TIMM50 translocase of inner mitochondrial membrane 50 2 2
MIRT641592 TNS4 tensin 4 2 2
MIRT644993 POLR2J3 RNA polymerase II subunit J3 2 2
MIRT645059 UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII 2 2
MIRT646948 UPK3BL uroplakin 3B like 1 2 2
MIRT647306 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT648300 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 4
MIRT649043 SLC1A2 solute carrier family 1 member 2 2 2
MIRT649884 SLFN12L schlafen family member 12 like 2 2
MIRT650196 DOCK7 dedicator of cytokinesis 7 2 2
MIRT654789 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT655667 NUP43 nucleoporin 43 2 2
MIRT655925 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT656433 MARCH6 membrane associated ring-CH-type finger 6 2 2
MIRT657713 GPC4 glypican 4 2 2
MIRT659302 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT659844 CAPZB capping actin protein of muscle Z-line beta subunit 2 2
MIRT660660 ANKFY1 ankyrin repeat and FYVE domain containing 1 2 2
MIRT661308 CPM carboxypeptidase M 2 2
MIRT661473 CHMP1B charged multivesicular body protein 1B 2 2
MIRT661906 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT662064 ZNF284 zinc finger protein 284 2 2
MIRT662491 ANGPT4 angiopoietin 4 2 2
MIRT662657 LRRC47 leucine rich repeat containing 47 2 2
MIRT662804 MSRB2 methionine sulfoxide reductase B2 2 2
MIRT663164 FGFR1OP FGFR1 oncogene partner 2 2
MIRT663376 ZNF770 zinc finger protein 770 2 4
MIRT663418 ZNF607 zinc finger protein 607 2 2
MIRT663990 WDR75 WD repeat domain 75 2 2
MIRT664157 APOBEC3F apolipoprotein B mRNA editing enzyme catalytic subunit 3F 2 4
MIRT664489 POLR3K RNA polymerase III subunit K 2 2
MIRT665058 CCDC77 coiled-coil domain containing 77 2 2
MIRT665080 CRIPT CXXC repeat containing interactor of PDZ3 domain 2 2
MIRT665420 WDR55 WD repeat domain 55 2 2
MIRT665716 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT665923 TBC1D19 TBC1 domain family member 19 2 4
MIRT666239 SLC38A7 solute carrier family 38 member 7 2 4
MIRT666840 PPTC7 PTC7 protein phosphatase homolog 2 2
MIRT667378 MOB1B MOB kinase activator 1B 2 2
MIRT667573 LONRF2 LON peptidase N-terminal domain and ring finger 2 2 2
MIRT667894 ING1 inhibitor of growth family member 1 2 2
MIRT667977 HECTD3 HECT domain E3 ubiquitin protein ligase 3 2 2
MIRT668197 GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2 2
MIRT668279 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 2
MIRT668386 FAT3 FAT atypical cadherin 3 2 2
MIRT668444 FAM208A family with sequence similarity 208 member A 2 2
MIRT668998 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT669180 CCNF cyclin F 2 2
MIRT669444 ATL3 atlastin GTPase 3 2 2
MIRT669661 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2 2
MIRT669890 KIAA0754 KIAA0754 2 4
MIRT669973 SSR3 signal sequence receptor subunit 3 2 2
MIRT670153 SLC29A4 solute carrier family 29 member 4 2 2
MIRT670240 TRIM13 tripartite motif containing 13 2 2
MIRT670274 CBY3 chibby family member 3 2 2
MIRT670358 ULBP3 UL16 binding protein 3 2 4
MIRT670627 BVES blood vessel epicardial substance 2 2
MIRT670731 HOOK3 hook microtubule tethering protein 3 2 2
MIRT670770 TRIM66 tripartite motif containing 66 2 2
MIRT670913 DESI1 desumoylating isopeptidase 1 2 2
MIRT671216 CLSTN1 calsyntenin 1 2 2
MIRT671398 ERCC6L2 ERCC excision repair 6 like 2 2 2
MIRT671427 TOX4 TOX high mobility group box family member 4 2 2
MIRT671654 TRUB2 TruB pseudouridine synthase family member 2 2 4
MIRT671702 PMPCA peptidase, mitochondrial processing alpha subunit 2 2
MIRT672136 PLEKHH1 pleckstrin homology, MyTH4 and FERM domain containing H1 2 2
MIRT672395 SLC10A6 solute carrier family 10 member 6 2 2
MIRT672508 GGCX gamma-glutamyl carboxylase 2 2
MIRT672572 RNF24 ring finger protein 24 2 2
MIRT672789 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT673019 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT673190 C10orf76 chromosome 10 open reading frame 76 2 2
MIRT673372 ZNF124 zinc finger protein 124 2 2
MIRT673495 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT673852 CAPN7 calpain 7 2 2
MIRT673929 ZNF500 zinc finger protein 500 2 2
MIRT673986 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT674076 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT674123 RPL7L1 ribosomal protein L7 like 1 2 2
MIRT674297 THAP5 THAP domain containing 5 2 2
MIRT674370 POLR3D RNA polymerase III subunit D 2 2
MIRT674641 NKRF NFKB repressing factor 2 2
MIRT674665 PLCE1 phospholipase C epsilon 1 2 2
MIRT674725 ZNF451 zinc finger protein 451 2 4
MIRT674779 NPR1 natriuretic peptide receptor 1 2 2
MIRT674889 RASSF9 Ras association domain family member 9 2 2
MIRT675017 SNX1 sorting nexin 1 2 2
MIRT675341 KLHL26 kelch like family member 26 2 2
MIRT675416 CLEC7A C-type lectin domain containing 7A 2 2
MIRT675497 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 2
MIRT675615 EHD2 EH domain containing 2 2 2
MIRT675735 AHR aryl hydrocarbon receptor 2 2
MIRT675857 ATP1B4 ATPase Na+/K+ transporting family member beta 4 2 2
MIRT675990 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT676213 TMEM91 transmembrane protein 91 2 2
MIRT676406 MRO maestro 2 2
MIRT677299 CPSF2 cleavage and polyadenylation specific factor 2 2 2
MIRT677387 PCNP PEST proteolytic signal containing nuclear protein 2 2
MIRT677859 ABI2 abl interactor 2 2 2
MIRT677965 ITGB3 integrin subunit beta 3 2 2
MIRT678175 CRCP CGRP receptor component 2 2
MIRT678273 PTRH2 peptidyl-tRNA hydrolase 2 2 2
MIRT678665 SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 2 2
MIRT679003 TTC39B tetratricopeptide repeat domain 39B 2 2
MIRT679053 RMDN1 regulator of microtubule dynamics 1 2 2
MIRT679461 RHOF ras homolog family member F, filopodia associated 2 2
MIRT679513 RAB36 RAB36, member RAS oncogene family 2 2
MIRT679914 ZKSCAN3 zinc finger with KRAB and SCAN domains 3 2 2
MIRT680029 OSBPL2 oxysterol binding protein like 2 2 4
MIRT680245 NDUFA7 NADH:ubiquinone oxidoreductase subunit A7 2 2
MIRT680279 AKIP1 A-kinase interacting protein 1 2 2
MIRT680499 PRIM2 DNA primase subunit 2 2 2
MIRT680586 ZNF573 zinc finger protein 573 2 2
MIRT680629 KIAA1456 KIAA1456 2 2
MIRT680819 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT680998 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT681122 INTS7 integrator complex subunit 7 2 2
MIRT681161 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT681221 DUSP19 dual specificity phosphatase 19 2 2
MIRT681304 IKZF3 IKAROS family zinc finger 3 2 2
MIRT681341 BRI3BP BRI3 binding protein 2 2
MIRT681608 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT681779 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681892 SLC11A2 solute carrier family 11 member 2 2 2
MIRT682084 ITGA3 integrin subunit alpha 3 2 4
MIRT682139 SMS spermine synthase 2 2
MIRT682217 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682367 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682535 EXOSC2 exosome component 2 2 2
MIRT682618 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT683643 ZNF695 zinc finger protein 695 2 2
MIRT684008 FOLR1 folate receptor 1 2 2
MIRT684442 MFSD4 major facilitator superfamily domain containing 4A 2 2
MIRT684855 ZNF749 zinc finger protein 749 2 2
MIRT684956 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT685044 GEMIN4 gem nuclear organelle associated protein 4 2 2
MIRT685095 DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 2 2
MIRT685382 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT685456 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT685810 SLC27A1 solute carrier family 27 member 1 2 2
MIRT685913 MOCS3 molybdenum cofactor synthesis 3 2 2
MIRT686665 TMEM120B transmembrane protein 120B 2 2
MIRT686955 SFT2D2 SFT2 domain containing 2 2 2
MIRT687118 QPCTL glutaminyl-peptide cyclotransferase like 2 2
MIRT687739 KIAA1328 KIAA1328 2 2
MIRT688063 GLUL glutamate-ammonia ligase 2 2
MIRT688191 FNIP1 folliculin interacting protein 1 2 2
MIRT688769 CDH7 cadherin 7 2 2
MIRT688979 ATP6AP1 ATPase H+ transporting accessory protein 1 2 2
MIRT689572 NUDT7 nudix hydrolase 7 2 2
MIRT689683 TMPRSS12 transmembrane protease, serine 12 2 2
MIRT689930 MANSC1 MANSC domain containing 1 2 2
MIRT690089 PNMA2 paraneoplastic Ma antigen 2 2 2
MIRT690190 C5orf45 MRN complex interacting protein 2 2
MIRT690246 CAMLG calcium modulating ligand 2 2
MIRT690411 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT690840 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT690889 FUT2 fucosyltransferase 2 2 2
MIRT691107 ADIPOQ adiponectin, C1Q and collagen domain containing 2 2
MIRT691229 DFNB59 pejvakin 2 2
MIRT691300 ZNF681 zinc finger protein 681 2 2
MIRT691366 GP5 glycoprotein V platelet 2 2
MIRT691797 WARS tryptophanyl-tRNA synthetase 2 2
MIRT692142 CEP104 centrosomal protein 104 2 2
MIRT692572 NCMAP non-compact myelin associated protein 2 2
MIRT692649 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT692744 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 2 2
MIRT693092 SCNM1 sodium channel modifier 1 2 2
MIRT693296 SYTL3 synaptotagmin like 3 2 2
MIRT693392 ZNF460 zinc finger protein 460 2 2
MIRT693530 ZNF708 zinc finger protein 708 2 2
MIRT693562 PIGR polymeric immunoglobulin receptor 2 2
MIRT694492 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT694722 LLGL1 LLGL1, scribble cell polarity complex component 2 2
MIRT694866 ZNF417 zinc finger protein 417 2 2
MIRT695070 ZNF17 zinc finger protein 17 2 2
MIRT695451 COX18 COX18, cytochrome c oxidase assembly factor 2 2
MIRT695724 ZNF117 zinc finger protein 117 2 2
MIRT695898 MED16 mediator complex subunit 16 2 2
MIRT696244 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT696259 TACO1 translational activator of cytochrome c oxidase I 2 2
MIRT696512 C3 complement C3 2 2
MIRT696560 TTC21B tetratricopeptide repeat domain 21B 2 2
MIRT696643 AGXT2 alanine--glyoxylate aminotransferase 2 2 2
MIRT696791 DHODH dihydroorotate dehydrogenase (quinone) 2 2
MIRT696819 PLLP plasmolipin 2 2
MIRT697088 GPKOW G-patch domain and KOW motifs 2 2
MIRT697153 INMT indolethylamine N-methyltransferase 2 2
MIRT697202 ZYG11A zyg-11 family member A, cell cycle regulator 2 2
MIRT697322 ZNF641 zinc finger protein 641 2 2
MIRT697578 YME1L1 YME1 like 1 ATPase 2 2
MIRT697619 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT698619 TES testin LIM domain protein 2 2
MIRT698804 STK38 serine/threonine kinase 38 2 2
MIRT698949 SPAST spastin 2 2
MIRT699083 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT699430 SLC1A5 solute carrier family 1 member 5 2 2
MIRT699550 SIT1 signaling threshold regulating transmembrane adaptor 1 2 2
MIRT700324 RAB4A RAB4A, member RAS oncogene family 2 2
MIRT700360 RAB33B RAB33B, member RAS oncogene family 2 2
MIRT700462 PURB purine rich element binding protein B 2 2
MIRT701677 MYADM myeloid associated differentiation marker 2 2
MIRT701757 MSL2 MSL complex subunit 2 2 2
MIRT701977 MIER3 MIER family member 3 2 2
MIRT703178 GPBP1 GC-rich promoter binding protein 1 2 2
MIRT703203 GOLGA3 golgin A3 2 2
MIRT703359 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT703425 FYTTD1 forty-two-three domain containing 1 2 2
MIRT703484 FNDC3B fibronectin type III domain containing 3B 2 2
MIRT703590 FBXO45 F-box protein 45 2 2
MIRT703806 EVI5 ecotropic viral integration site 5 2 2
MIRT703915 EPG5 ectopic P-granules autophagy protein 5 homolog 2 2
MIRT704234 DHDDS dehydrodolichyl diphosphate synthase subunit 2 2
MIRT704646 CLCC1 chloride channel CLIC like 1 2 2
MIRT705151 C11orf58 chromosome 11 open reading frame 58 2 2
MIRT705480 ASXL2 additional sex combs like 2, transcriptional regulator 2 2
MIRT705530 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT705661 ANKRD40 ankyrin repeat domain 40 2 2
MIRT706144 ZNF674 zinc finger protein 674 2 2
MIRT706473 SNX27 sorting nexin family member 27 2 2
MIRT708254 PGPEP1 pyroglutamyl-peptidase I 2 2
MIRT708838 SCAND3 zinc finger BED-type containing 9 1 1
MIRT710437 BTNL3 butyrophilin like 3 2 2
MIRT711325 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT716151 RBM48 RNA binding motif protein 48 2 2
MIRT717402 ZCCHC24 zinc finger CCHC-type containing 24 2 2
MIRT720866 ADCY5 adenylate cyclase 5 2 2
MIRT722226 ZNF503 zinc finger protein 503 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-1273h-5p Paclitaxel 36314 NSC125973 approved sensitive High Ovarian Cancer cell line (SKOV3)
hsa-miR-1273h-5p Tripterygium wilfordii Hook F resistant tissue
hsa-miR-1273h-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)

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