miRTarBase - #MIRT629867


—
pre-miRNA Information
pre-miRNA hsa-mir-3140   
Genomic Coordinates chr4: 152489327 - 152489416
Description Homo sapiens miR-3140 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3140-5p
Sequence 12| ACCUGAAUUACCAAAAGCUUU |32
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs916622204 2 dbSNP
rs1445802016 3 dbSNP
rs1173519977 6 dbSNP
rs765680332 20 dbSNP
Putative Targets

Gene Information
Gene Symbol GATAD1   
Synonyms CMD2B, ODAG, RG083M05.2
Description GATA zinc finger domain containing 1
Transcript NM_021167   
Expression
Putative miRNA Targets on GATAD1
3'UTR of GATAD1
(miRNA target sites are highlighted)		 
>GATAD1|NM_021167|3'UTR
   1 TTCACAAATTAAAACTGGGTTTCCAGGCCTGGTGTGGTGGCTCACGCCTGTAGCCCCAGCTATTGCACCACTGCTCTCCA
  81 AGCTGGGCAATGGAGTCAGATTCTCTTTCTTAAAAAACCACAAAAAAACTGGATTTCCAGTTCTCTAATATTCTTAGTAC
 161 CACAAGATATGTCATAGGTATCTTTAAATGAAATTCTTAGCTGGAAAAGTGACTAAAAAGTTTTTCTCCTGCTACCTAGT
 241 AATAAACAAATCATTGTTTATTACTGGTCACTTAGAAAATTAAAAGGGATAGGGCCAGGCACAGTGGCTTATGCCTGTAA
 321 TTGCAGCACTTTTAGAGGCCGAGGCAGGCGGATCACCTGAGGTCGGGAAGTGGATCGCCTGAGGTCAGGAGTTCGAGACC
 401 AGCCTGGCCAACATGGCGAAACCCCGTCGCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGCATGTGCCTGTAATCC
 481 CAGCTATTTGGGAGGCTGAGGCAGGAGAATCGCCTAAACCCAGGAGGTGGAGGTTGTAGTGAGCCAAGATTGCACCGCTG
 561 TGCTCCAGCCTGGGCAACAGAGTGAGACTCTTGTCTCGGAAAAAAAAAAAAAAAAAAAAGGCTGGGCACAGTGGCTCACG
 641 CCTTTAATCCCAGCACTTTGGGAGGCTGAGGCAGATGGATCGCCTGAGGTTGGGAGTTCGAGACCAGCCTGGCCAGCATG
 721 GTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGCGCACACCTGTAGTCCCAGCTACTCGGGAGG
 801 CTGAGGCAGGAGAATTGGTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCAGAGATCGTGCCACTGCACTCCAGCCTGGGT
 881 GGACAGAGCAAGACTCCGTCTCAAAGAAACAAACAAAAAATTAAAAGGGATAGAATATAATGAAATATATTTTGAACTTA
 961 AATTATATTCTATATGTGTATCTTCCTAGGCAAAAGCTGTAATTTCCAGAGAGACCATTAGGAACAGGTAGTATCTATTT
1041 TTCTCCATTATTTATTTCTAGAAACTCATAAAATGGATTGTATTTTTCTATAAGAACAAAATATTAATTAAGGTATAGAT
1121 GACTGACCAAGGGCTTAATCAAATAAAATGACTAACAGCATCTATCATAAAGCCACACAAGCCTTATGTTCTCATCTCAA
1201 AAATGCTGTGACAGCTTTTTGGCTGCTTTAACCATAAGAAAAATGATTGGTGGATGATTTTATTAGCCCAGGCTTTTAAA
1281 AACTTTCATCTAGGCCACGTGCGGTGGCTCATGCCTGTAATCCCGGCACTTTGGGAGGCCTGAGTGGATGGATCACTTGA
1361 GGTCAGGAGTTCAGGACCAGCCTGGCCAACATGATGAAACCCTGTCTCTACTAAATATACAAAAATTAGTTGGGTGTTAT
1441 GGTGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACTCGGGAGGTGGAGATTGCAGTAA
1521 GCCGAGATCGTGCCACTGCACTCCAGCCTGGGTGATAGAGCAAGACTGTCTCAAAAAAGAAAAAAAAGAAAAAATTTTAA
1601 TTTAATCCTTCTGTAGAAACAGGCATTCAGAACCATTCCATTGATCTTAATAAAGCTGCTCTTTACTGTTTCTAGTCAAA
1681 AATGAGACTTCGATCAAACCATAAGATTTTATACTGCAGATAGTCAGCTTCACCAAAGCCGCAGAGGAAACATGTCGAGA
1761 TCAGGCTTCCTGCTTGATAGTCTCTTGACTACCATTAAAACGAATATTGGGAGGTCATGAAAGTCATTGGTAGGCCATTA
1841 GCATTGATATCTTTAAAACATCTACCCTAAACCATCTGCTATGGACCCATAATAAGAGGCCTGTTGTATATGAAATTGTC
1921 TAGAATTCAGGTGCAGGTCTTTGCCGGTTAAGTAAGGGAGCAACACGTAAAATGGGAGAGGAGTGGGGTGTACTCACTTG
2001 CCTCCTCTTTTGTCCTGATTTAACCAGCATTTTTCAACCCTGGGAAAATTTGCAGAATCTAAGTTGATTGTAATGATTTT
2081 GAGCTGCAGCAGCTTTAACTCTTACCCTTTTTCCACATAGTTATGGTGTTTGAGTTGGAAAGAAACAACTATAGGTAGCT
2161 ACACGTACATAATTATCTCTTTATTCACAAAGGGTATAGTAAAATTGATTGTAAATAACTTTCTAAGTGCCAATATTCAA
2241 AACTTTTGGATTAAAATGTATTTTTCACCGTGCATTTACTTTGGATGTATTTATTTCATTTAAACAATTTAAATGGGGCT
2321 CTTTAACCAAAAATGGTATTTAAAACCAAAACAGTATCGTACTTAGAATTTGGAGTAGAGGCCGGGCACAGTGGCTCACG
2401 CCTGTAATCCCAGCACTTTGGAAGGCTGAGGCAGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGTCAACATG
2481 AAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGCGTGCGCCTATAATCCCAGCTAGTCTACTCGGGA
2561 GGCTGAGGCAGGAGAATCGCTGGAACTCAGGAGGCAGAGACTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGTCTGG
2641 GTGACGGCATGACTCCATCTCCAAAAAAAAAAAAAAAAGATTTTGGAGTAGATTCATCATTAATAAGTAACAGATTTTAG
2721 GAAAATCAAAAAATGGCTAATAAAATGAACACAATGTAAAACATTTATTAAAATGTAGACTTTTAAAAATCTATAAATTG
2801 ATCATCTGTTTATAAATTGGCAGATGGTTGTGTACCATCTTTTAAAATAAAGATTGAATTTCACCCAGTGTGATGGTTCC
2881 CATTGCTTATATTTCTCCTGCTGAGGCCGGACCTGATATGGCCCTGGTCTGTGTTCCCAGCCTTGTTTCCTCATTACCAC
2961 TAAAATCTTTCCCCTGTATGCCCGCCCAATTTTTCTGGCTCTGAGTCCTTGTTCATACTGTTCTCTCCAATTCTACCTTC
3041 CAAAGGCCTTTCTTAACACCTTCGGATTCTTTCTTTGAGAACTTTCCAGATTCCCATGCCTTTTTGGAATCAATCTCTAT
3121 CCTATTGTCATCACATTTAAGTTTCTACTTCCATCATCCTCACTCCTATCCCTTTGGTCCTGGGATGACAGGGATGCTGT
3201 GTTTTATTTACTCATCTTTGTAACTTCCACATAACCTAACCCCGGTTCTTGCTTATGGGAGATGCTGATTGTAGGGTCTG
3281 AGTTAGATACTGTTAACTAAAATGCTTGTTGATATTTTAGTTATTAATTCATATTAACTTTGGCTGAAACTTTTAAATTC
3361 TATTGTGAATAGTCAAGTAAAATTTAGATTGTTACATTCTGGGTTAGTATTAGATTGTTTTTAAGATTGTTTTAAACAAG
3441 ATGTTTTTAAGATGAGTTTTAAATAGTTCTCTTAACACAAATAAAGCTTAATATGAGTATTTGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuucgaAAACCAUUAAGUCCa 5'
                | | | |||||||| 
Target 5' aaattgTCTAG-AATTCAGGt 3'
 1913 - 1932 146.00 -10.10
2 
miRNA  3' uuucGAAAACCA----UUAAGUCCa 5'
              |||  |||    |:|||||| 
Target 5' atcaCTTGAGGTCAGGAGTTCAGGa 3'
 1352 - 1376 139.00 -13.50
3 
miRNA  3' uuUCGAAAAC--CAU-UAAGUcca 5'
            || |||||  ||| |||||   
Target 5' aaAGATTTTGGAGTAGATTCAtca 3'
 2676 - 2699 129.00 -7.22
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
197844 5 ClinVar
COSN30473727 2 COSMIC
COSN30191778 4 COSMIC
COSN31550532 16 COSMIC
COSN30456331 18 COSMIC
COSN31500884 18 COSMIC
COSN30487566 24 COSMIC
COSN31598304 41 COSMIC
COSN30505277 47 COSMIC
COSN30176449 55 COSMIC
COSN30177368 59 COSMIC
COSN28846114 118 COSMIC
COSN31580949 119 COSMIC
COSN25730291 418 COSMIC
COSN25731485 426 COSMIC
COSN23925064 693 COSMIC
COSN9515927 785 COSMIC
COSN25733267 795 COSMIC
COSN27713406 971 COSMIC
COSN24543862 1304 COSMIC
COSN20104440 1617 COSMIC
COSN16458761 1660 COSMIC
COSN9774111 1713 COSMIC
COSN17828123 1781 COSMIC
COSN21780725 2024 COSMIC
COSN7659708 2245 COSMIC
COSN20091636 2270 COSMIC
COSN8046910 2270 COSMIC
COSN9774112 2566 COSMIC
COSN20104441 2646 COSMIC
COSN20091637 2656 COSMIC
COSN8046911 2714 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs768338694 5 dbSNP
rs776572083 6 dbSNP
rs1441703333 8 dbSNP
rs1172019632 14 dbSNP
rs933689397 18 dbSNP
rs1466641691 19 dbSNP
rs1337076822 21 dbSNP
rs1305074542 24 dbSNP
rs1395033317 29 dbSNP
rs1464922722 30 dbSNP
rs201484113 33 dbSNP
rs1172124956 34 dbSNP
rs1428558049 37 dbSNP
rs1412503077 42 dbSNP
rs765227703 46 dbSNP
rs373951368 47 dbSNP
rs759662364 49 dbSNP
rs1302267586 50 dbSNP
rs368432655 51 dbSNP
rs1234834943 53 dbSNP
rs891634172 54 dbSNP
rs1205551845 61 dbSNP
rs747154768 63 dbSNP
rs1343534228 68 dbSNP
rs1287905753 70 dbSNP
rs1453120737 77 dbSNP
rs1010065606 84 dbSNP
rs374444749 91 dbSNP
rs954989187 102 dbSNP
rs988996607 108 dbSNP
rs1319855249 110 dbSNP
rs1374433879 112 dbSNP
rs1299500739 114 dbSNP
rs1462225489 116 dbSNP
rs188184603 119 dbSNP
rs1454433146 120 dbSNP
rs1426017032 122 dbSNP
rs527279475 122 dbSNP
rs907102137 133 dbSNP
rs1178613044 139 dbSNP
rs1438200793 147 dbSNP
rs1312666343 158 dbSNP
rs1378092150 164 dbSNP
rs1177994139 165 dbSNP
rs554422926 166 dbSNP
rs1488243502 168 dbSNP
rs1020892708 172 dbSNP
rs1224755317 173 dbSNP
rs1308661691 176 dbSNP
rs968875581 177 dbSNP
rs532959055 180 dbSNP
rs1292365859 189 dbSNP
rs1001566433 200 dbSNP
rs1351210452 201 dbSNP
rs1034364484 215 dbSNP
rs1214448705 218 dbSNP
rs6945183 221 dbSNP
rs925092424 232 dbSNP
rs1291451215 244 dbSNP
rs1406216576 247 dbSNP
rs1365713749 250 dbSNP
rs750513279 256 dbSNP
rs534021139 265 dbSNP
rs917575247 269 dbSNP
rs1418480767 283 dbSNP
rs1463059997 284 dbSNP
rs1366066828 291 dbSNP
rs1160221343 295 dbSNP
rs949294909 301 dbSNP
rs962556294 302 dbSNP
rs976273264 304 dbSNP
rs1262635857 305 dbSNP
rs1490527169 305 dbSNP
rs1047654825 313 dbSNP
rs1179223041 314 dbSNP
rs886271595 317 dbSNP
rs1406025998 323 dbSNP
rs1311421225 326 dbSNP
rs150695878 341 dbSNP
rs1225030467 349 dbSNP
rs1177232864 351 dbSNP
rs1408321552 362 dbSNP
rs1397609187 365 dbSNP
rs577230002 366 dbSNP
rs1465825479 367 dbSNP
rs900622613 367 dbSNP
rs1376330760 373 dbSNP
rs1470920637 374 dbSNP
rs780292239 377 dbSNP
rs181373976 378 dbSNP
rs1423186072 380 dbSNP
rs1442619905 389 dbSNP
rs768520972 395 dbSNP
rs185650494 396 dbSNP
rs1227335082 412 dbSNP
rs370668157 413 dbSNP
rs1020501883 414 dbSNP
rs1482798988 417 dbSNP
rs969368278 418 dbSNP
rs978993381 419 dbSNP
rs370697560 426 dbSNP
rs1224565209 427 dbSNP
rs1207059376 429 dbSNP
rs1231452986 430 dbSNP
rs959138053 435 dbSNP
rs1404352928 448 dbSNP
rs1339026220 450 dbSNP
rs1470514542 454 dbSNP
rs1399772002 456 dbSNP
rs1480439442 459 dbSNP
rs1312321990 462 dbSNP
rs1373777467 471 dbSNP
rs1193808550 475 dbSNP
rs990539481 481 dbSNP
rs1241214544 482 dbSNP
rs374078447 493 dbSNP
rs1461632099 495 dbSNP
rs576005246 512 dbSNP
rs138977267 513 dbSNP
rs1174236224 514 dbSNP
rs1424362416 515 dbSNP
rs1410378034 517 dbSNP
rs1054169644 522 dbSNP
rs970340233 523 dbSNP
rs143316680 528 dbSNP
rs1352477926 529 dbSNP
rs1408870894 530 dbSNP
rs189237292 533 dbSNP
rs541255027 534 dbSNP
rs1346901774 535 dbSNP
rs1402521759 538 dbSNP
rs941938098 545 dbSNP
rs1162681298 547 dbSNP
rs945895812 550 dbSNP
rs567260225 553 dbSNP
rs1165441744 556 dbSNP
rs564412708 557 dbSNP
rs1271335222 558 dbSNP
rs1179216349 561 dbSNP
rs1439120072 564 dbSNP
rs907002171 567 dbSNP
rs1001471523 568 dbSNP
rs1341851490 573 dbSNP
rs1356683568 578 dbSNP
rs1223532367 580 dbSNP
rs1247407815 590 dbSNP
rs367987228 591 dbSNP
rs1278081557 598 dbSNP
rs763393241 598 dbSNP
rs1444832076 599 dbSNP
rs1055680688 600 dbSNP
rs1156528641 600 dbSNP
rs1304868133 600 dbSNP
rs1336529894 600 dbSNP
rs1471051701 600 dbSNP
rs1491076553 600 dbSNP
rs35310565 600 dbSNP
rs397889621 600 dbSNP
rs397889850 600 dbSNP
rs71528045 600 dbSNP
rs1025297577 601 dbSNP
rs1489898597 602 dbSNP
rs1197770239 606 dbSNP
rs1489625005 607 dbSNP
rs887786058 613 dbSNP
rs75869278 620 dbSNP
rs1242713725 621 dbSNP
rs1006217750 622 dbSNP
rs1475702671 623 dbSNP
rs1169536759 624 dbSNP
rs867950604 631 dbSNP
rs951066696 633 dbSNP
rs1417154428 640 dbSNP
rs1015461561 641 dbSNP
rs1163874623 644 dbSNP
rs932088531 646 dbSNP
rs962133224 652 dbSNP
rs1051759679 657 dbSNP
rs28392652 659 dbSNP
rs1010227581 666 dbSNP
rs1042108524 673 dbSNP
rs1344482232 679 dbSNP
rs181872371 682 dbSNP
rs1000841075 683 dbSNP
rs1268886050 685 dbSNP
rs1175245118 693 dbSNP
rs373025534 700 dbSNP
rs1430993328 701 dbSNP
rs1199449923 708 dbSNP
rs1247165780 717 dbSNP
rs958836112 721 dbSNP
rs1294290318 729 dbSNP
rs1240834409 737 dbSNP
rs1218620892 745 dbSNP
rs1357568185 749 dbSNP
rs570035983 750 dbSNP
rs1024693250 751 dbSNP
rs1202170878 755 dbSNP
rs1209395511 757 dbSNP
rs1325855000 762 dbSNP
rs1284187076 763 dbSNP
rs763886126 767 dbSNP
rs1360002560 770 dbSNP
rs1448760456 770 dbSNP
rs529318998 771 dbSNP
rs907513021 772 dbSNP
rs963341045 775 dbSNP
rs1448717219 776 dbSNP
rs1183956953 780 dbSNP
rs1386799836 783 dbSNP
rs1335772162 786 dbSNP
rs957076113 787 dbSNP
rs989815971 791 dbSNP
rs1442403011 793 dbSNP
rs973707407 795 dbSNP
rs186546798 796 dbSNP
rs1401920418 803 dbSNP
rs1475987162 810 dbSNP
rs1243082876 818 dbSNP
rs1253658050 819 dbSNP
rs1420564675 820 dbSNP
rs1316920376 831 dbSNP
rs1462958585 832 dbSNP
rs1263954185 833 dbSNP
rs1285612336 834 dbSNP
rs566214031 835 dbSNP
rs533956099 845 dbSNP
rs1453931670 855 dbSNP
rs147516879 858 dbSNP
rs796572357 859 dbSNP
rs6946180 860 dbSNP
rs6945918 861 dbSNP
rs1441118382 862 dbSNP
rs1352408448 863 dbSNP
rs1171830514 864 dbSNP
rs1410059570 865 dbSNP
rs1385111371 866 dbSNP
rs1162266273 885 dbSNP
rs1446797698 888 dbSNP
rs762505687 890 dbSNP
rs1041750612 893 dbSNP
rs1244194898 896 dbSNP
rs183734072 897 dbSNP
rs1352984012 898 dbSNP
rs541495400 899 dbSNP
rs1358868673 907 dbSNP
rs1000470399 910 dbSNP
rs1266227526 915 dbSNP
rs1243764596 929 dbSNP
rs1361329295 933 dbSNP
rs555418017 934 dbSNP
rs376027789 940 dbSNP
rs1315401219 949 dbSNP
rs1223008551 950 dbSNP
rs894652062 953 dbSNP
rs1370657457 957 dbSNP
rs1299555155 958 dbSNP
rs1055754845 960 dbSNP
rs1364463470 974 dbSNP
rs571829339 975 dbSNP
rs541193531 979 dbSNP
rs1386414272 986 dbSNP
rs1204147729 987 dbSNP
rs1024474284 988 dbSNP
rs1417736348 1001 dbSNP
rs1410405188 1010 dbSNP
rs1244783192 1012 dbSNP
rs1178048106 1014 dbSNP
rs970487520 1015 dbSNP
rs1266950383 1018 dbSNP
rs1224827982 1022 dbSNP
rs1490804763 1035 dbSNP
rs1265980038 1048 dbSNP
rs1214753765 1066 dbSNP
rs1314949684 1075 dbSNP
rs1421787247 1081 dbSNP
rs1224048085 1082 dbSNP
rs564350195 1083 dbSNP
rs1006248807 1090 dbSNP
rs1005013066 1091 dbSNP
rs897789497 1098 dbSNP
rs1186464069 1102 dbSNP
rs1452053720 1103 dbSNP
rs1347377977 1104 dbSNP
rs1364012193 1113 dbSNP
rs1160103008 1116 dbSNP
rs1480196676 1119 dbSNP
rs573126382 1120 dbSNP
rs111671363 1122 dbSNP
rs1427483374 1126 dbSNP
rs370361135 1127 dbSNP
rs1014611731 1139 dbSNP
rs1156314606 1141 dbSNP
rs963336564 1144 dbSNP
rs1470606282 1149 dbSNP
rs1204532484 1160 dbSNP
rs533401128 1163 dbSNP
rs1484762203 1165 dbSNP
rs1262336717 1166 dbSNP
rs1209126535 1167 dbSNP
rs1322323235 1191 dbSNP
rs544094535 1194 dbSNP
rs1028900905 1201 dbSNP
rs770392610 1204 dbSNP
rs997627738 1209 dbSNP
rs1030789811 1216 dbSNP
rs550071097 1216 dbSNP
rs534359179 1223 dbSNP
rs1007681208 1227 dbSNP
rs1364707456 1228 dbSNP
rs1329874538 1233 dbSNP
rs1032581268 1234 dbSNP
rs1237082627 1247 dbSNP
rs987290679 1248 dbSNP
rs1178896938 1249 dbSNP
rs1287814524 1250 dbSNP
rs529274207 1251 dbSNP
rs1470330249 1253 dbSNP
rs911714201 1255 dbSNP
rs958271244 1258 dbSNP
rs946164969 1266 dbSNP
rs549139067 1270 dbSNP
rs1426596052 1278 dbSNP
rs1264905843 1284 dbSNP
rs566142457 1288 dbSNP
rs1482178079 1293 dbSNP
rs1188922756 1296 dbSNP
rs186193815 1299 dbSNP
rs1250896928 1300 dbSNP
rs1205243560 1304 dbSNP
rs1345108396 1307 dbSNP
rs764386383 1309 dbSNP
rs1224633621 1310 dbSNP
rs1019968540 1313 dbSNP
rs935965592 1318 dbSNP
rs1299027783 1321 dbSNP
rs1055793897 1323 dbSNP
rs981222702 1324 dbSNP
rs547565517 1325 dbSNP
rs950260933 1326 dbSNP
rs1166172748 1333 dbSNP
rs1045959768 1340 dbSNP
rs1463611298 1348 dbSNP
rs1179258413 1353 dbSNP
rs1374695119 1356 dbSNP
rs1169198103 1362 dbSNP
rs887251092 1365 dbSNP
rs1443769215 1373 dbSNP
rs1241115800 1378 dbSNP
rs1185207527 1380 dbSNP
rs909157119 1390 dbSNP
rs941969794 1392 dbSNP
rs1465905879 1398 dbSNP
rs754208386 1401 dbSNP
rs1015054285 1412 dbSNP
rs540527810 1417 dbSNP
rs1307601437 1418 dbSNP
rs1346287579 1428 dbSNP
rs1406817011 1433 dbSNP
rs1357732316 1435 dbSNP
rs1285190010 1437 dbSNP
rs1317525404 1440 dbSNP
rs10257981 1441 dbSNP
rs889182839 1445 dbSNP
rs1327151462 1449 dbSNP
rs1393191483 1458 dbSNP
rs1028599873 1464 dbSNP
rs749132112 1465 dbSNP
rs987321928 1466 dbSNP
rs1018750665 1468 dbSNP
rs1308559570 1469 dbSNP
rs1423857063 1472 dbSNP
rs1032486742 1473 dbSNP
rs1251702987 1481 dbSNP
rs893953101 1485 dbSNP
rs1473024265 1490 dbSNP
rs145462751 1491 dbSNP
rs144270677 1492 dbSNP
rs1420335842 1493 dbSNP
rs1251987080 1494 dbSNP
rs1221097459 1495 dbSNP
rs535401606 1500 dbSNP
rs189648294 1501 dbSNP
rs1210768608 1503 dbSNP
rs1350468178 1507 dbSNP
rs1277991890 1508 dbSNP
rs1241531526 1513 dbSNP
rs936097147 1517 dbSNP
rs1351345619 1520 dbSNP
rs182671831 1524 dbSNP
rs540731965 1525 dbSNP
rs950299683 1528 dbSNP
rs557603419 1530 dbSNP
rs557478055 1555 dbSNP
rs1384042469 1557 dbSNP
rs887291544 1561 dbSNP
rs1412271079 1564 dbSNP
rs1375249110 1565 dbSNP
rs1479188971 1566 dbSNP
rs1446781548 1573 dbSNP
rs909062794 1573 dbSNP
rs941817042 1573 dbSNP
rs577809482 1576 dbSNP
rs1411940090 1578 dbSNP
rs7784223 1579 dbSNP
rs1221727154 1580 dbSNP
rs1262783817 1580 dbSNP
rs1330030525 1580 dbSNP
rs1347525358 1580 dbSNP
rs7784597 1580 dbSNP
rs919168199 1587 dbSNP
rs7784226 1588 dbSNP
rs7784605 1589 dbSNP
rs543691952 1592 dbSNP
rs7784228 1595 dbSNP
rs1315891718 1598 dbSNP
rs1458639242 1601 dbSNP
rs1388866238 1608 dbSNP
rs181265496 1616 dbSNP
rs75613288 1616 dbSNP
rs113105390 1617 dbSNP
rs1175315936 1617 dbSNP
rs1426739748 1620 dbSNP
rs1172657689 1624 dbSNP
rs1475339545 1628 dbSNP
rs1240885219 1630 dbSNP
rs751771751 1631 dbSNP
rs1375167869 1634 dbSNP
rs186994003 1641 dbSNP
rs367677614 1645 dbSNP
rs1202079475 1648 dbSNP
rs1168246513 1661 dbSNP
rs898936561 1668 dbSNP
rs34343533 1678 dbSNP
rs994535367 1683 dbSNP
rs1366428252 1690 dbSNP
rs563989578 1693 dbSNP
rs1291859108 1694 dbSNP
rs888756834 1699 dbSNP
rs1268376388 1702 dbSNP
rs1436969131 1706 dbSNP
rs943475657 1715 dbSNP
rs1335667967 1719 dbSNP
rs1366946204 1722 dbSNP
rs1386159080 1726 dbSNP
rs1296178599 1728 dbSNP
rs1360551761 1737 dbSNP
rs1053760038 1741 dbSNP
rs574276877 1742 dbSNP
rs1417950061 1746 dbSNP
rs148717683 1746 dbSNP
rs1385080314 1751 dbSNP
rs559783173 1757 dbSNP
rs1238292459 1758 dbSNP
rs893984226 1778 dbSNP
rs1270771201 1779 dbSNP
rs1230606390 1784 dbSNP
rs1342790662 1790 dbSNP
rs747959207 1792 dbSNP
rs1243527000 1793 dbSNP
rs1018782100 1794 dbSNP
rs1303105600 1801 dbSNP
rs967310455 1802 dbSNP
rs769530251 1803 dbSNP
rs1021246357 1805 dbSNP
rs1430886877 1806 dbSNP
rs1365526931 1821 dbSNP
rs1273540535 1822 dbSNP
rs906760062 1828 dbSNP
rs1032826843 1833 dbSNP
rs1002570074 1840 dbSNP
rs867643251 1842 dbSNP
rs777739151 1848 dbSNP
rs915917244 1850 dbSNP
rs1205971705 1851 dbSNP
rs971355222 1856 dbSNP
rs1483312949 1862 dbSNP
rs981433547 1863 dbSNP
rs561085755 1875 dbSNP
rs1265545953 1882 dbSNP
rs1323330383 1886 dbSNP
rs770429958 1890 dbSNP
rs940269522 1893 dbSNP
rs1222922797 1904 dbSNP
rs773865764 1911 dbSNP
rs1370736040 1921 dbSNP
rs1038973862 1923 dbSNP
rs1409930638 1935 dbSNP
rs1345393430 1937 dbSNP
rs191480624 1946 dbSNP
rs552759747 1947 dbSNP
rs1350890757 1964 dbSNP
rs551892949 1967 dbSNP
rs776577594 1968 dbSNP
rs1182937414 1969 dbSNP
rs1480172436 1974 dbSNP
rs930415634 1977 dbSNP
rs1268065499 1981 dbSNP
rs34606827 1985 dbSNP
rs1050095487 1986 dbSNP
rs1489335797 1987 dbSNP
rs1265747110 1989 dbSNP
rs745459455 1990 dbSNP
rs1326587601 1998 dbSNP
rs1162881446 2002 dbSNP
rs1349420102 2015 dbSNP
rs1344376587 2018 dbSNP
rs1454345678 2024 dbSNP
rs371632143 2030 dbSNP
rs183702741 2040 dbSNP
rs1289443255 2047 dbSNP
rs1368931618 2048 dbSNP
rs1288603613 2051 dbSNP
rs1390724771 2059 dbSNP
rs919212143 2069 dbSNP
rs1296606265 2075 dbSNP
rs1469340286 2076 dbSNP
rs1383207060 2077 dbSNP
rs888787863 2080 dbSNP
rs573181080 2091 dbSNP
rs1310111830 2101 dbSNP
rs1434782968 2103 dbSNP
rs1268001204 2104 dbSNP
rs1185677435 2105 dbSNP
rs1463411016 2106 dbSNP
rs1249481634 2108 dbSNP
rs1320637600 2111 dbSNP
rs549731604 2113 dbSNP
rs1209030523 2116 dbSNP
rs188250836 2125 dbSNP
rs535394734 2128 dbSNP
rs998768784 2140 dbSNP
rs1263082112 2147 dbSNP
rs1033270772 2152 dbSNP
rs1463935067 2160 dbSNP
rs1208601563 2163 dbSNP
rs1244152615 2164 dbSNP
rs957189336 2165 dbSNP
rs548525500 2166 dbSNP
rs1321459863 2167 dbSNP
rs1452101602 2170 dbSNP
rs1462915168 2174 dbSNP
rs1304614514 2176 dbSNP
rs1466646384 2177 dbSNP
rs1378105614 2178 dbSNP
rs1013015200 2180 dbSNP
rs1169714603 2180 dbSNP
rs1447421200 2183 dbSNP
rs1391857829 2186 dbSNP
rs376068569 2190 dbSNP
rs565335378 2194 dbSNP
rs1023089561 2195 dbSNP
rs971468493 2197 dbSNP
rs981466488 2198 dbSNP
rs1483317540 2199 dbSNP
rs1419807788 2202 dbSNP
rs1251229040 2205 dbSNP
rs908528284 2212 dbSNP
rs1053833041 2213 dbSNP
rs961944811 2215 dbSNP
rs915309687 2217 dbSNP
rs945588452 2219 dbSNP
rs1045701 2221 dbSNP
rs974329921 2234 dbSNP
rs920089051 2247 dbSNP
rs1315158292 2250 dbSNP
rs1396658200 2252 dbSNP
rs77607170 2267 dbSNP
rs796333236 2268 dbSNP
rs540316918 2270 dbSNP
rs1055343923 2271 dbSNP
rs944441460 2273 dbSNP
rs1012578543 2274 dbSNP
rs1366328059 2280 dbSNP
rs1449920522 2285 dbSNP
rs1189255792 2288 dbSNP
rs557418474 2291 dbSNP
rs142251156 2294 dbSNP
rs1202420650 2297 dbSNP
rs999196305 2306 dbSNP
rs1054347235 2308 dbSNP
rs1276019441 2313 dbSNP
rs1222179364 2315 dbSNP
rs893052326 2318 dbSNP
rs1026586352 2319 dbSNP
rs954530115 2322 dbSNP
rs1326397144 2325 dbSNP
rs1245889963 2329 dbSNP
rs1335403608 2330 dbSNP
rs1286471553 2333 dbSNP
rs1228369346 2334 dbSNP
rs368448866 2336 dbSNP
rs1264265314 2337 dbSNP
rs1012796414 2339 dbSNP
rs1352222327 2349 dbSNP
rs1308609169 2355 dbSNP
rs1022786670 2357 dbSNP
rs987358041 2359 dbSNP
rs537626577 2360 dbSNP
rs1164783023 2372 dbSNP
rs1458040874 2379 dbSNP
rs910461579 2383 dbSNP
rs1253141859 2384 dbSNP
rs907317209 2384 dbSNP
rs989421705 2385 dbSNP
rs1450235247 2392 dbSNP
rs1292385626 2398 dbSNP
rs1237204151 2400 dbSNP
rs915358209 2401 dbSNP
rs1266516059 2402 dbSNP
rs1230276650 2407 dbSNP
rs1329991676 2410 dbSNP
rs538201902 2413 dbSNP
rs1249745571 2417 dbSNP
rs574224998 2419 dbSNP
rs1329282109 2426 dbSNP
rs1325221140 2436 dbSNP
rs193277491 2437 dbSNP
rs1156572475 2438 dbSNP
rs961364001 2439 dbSNP
rs974735977 2442 dbSNP
rs928124362 2446 dbSNP
rs1158391881 2447 dbSNP
rs939464219 2450 dbSNP
rs1429905107 2451 dbSNP
rs1477294241 2452 dbSNP
rs1416021067 2453 dbSNP
rs1248990732 2456 dbSNP
rs1027270412 2460 dbSNP
rs954289943 2461 dbSNP
rs985614132 2470 dbSNP
rs1455107463 2478 dbSNP
rs762205240 2479 dbSNP
rs1465515063 2486 dbSNP
rs1262523457 2488 dbSNP
rs1217565558 2489 dbSNP
rs1309443925 2493 dbSNP
rs1276589860 2496 dbSNP
rs560127916 2497 dbSNP
rs201438839 2498 dbSNP
rs1364272093 2507 dbSNP
rs369669125 2512 dbSNP
rs573257364 2515 dbSNP
rs1436742639 2517 dbSNP
rs565018140 2520 dbSNP
rs1370378837 2521 dbSNP
rs924280382 2528 dbSNP
rs1427838966 2529 dbSNP
rs1173733124 2532 dbSNP
rs1278398422 2533 dbSNP
rs532505956 2537 dbSNP
rs763382237 2538 dbSNP
rs1272717459 2544 dbSNP
rs1037788719 2549 dbSNP
rs898809540 2554 dbSNP
rs1482809857 2555 dbSNP
rs893083259 2558 dbSNP
rs151245478 2560 dbSNP
rs1201035937 2572 dbSNP
rs1271073934 2575 dbSNP
rs1044265790 2579 dbSNP
rs1295055971 2580 dbSNP
rs907012891 2584 dbSNP
rs1365424016 2590 dbSNP
rs1283285076 2593 dbSNP
rs1017498840 2595 dbSNP
rs1478973067 2601 dbSNP
rs1003373614 2603 dbSNP
rs964586018 2606 dbSNP
rs989328826 2613 dbSNP
rs1015642944 2614 dbSNP
rs897222406 2615 dbSNP
rs530924680 2619 dbSNP
rs1170826983 2620 dbSNP
rs774804335 2621 dbSNP
rs995558030 2622 dbSNP
rs1450528227 2623 dbSNP
rs1026921524 2633 dbSNP
rs1022734918 2646 dbSNP
rs112382994 2646 dbSNP
rs1473817292 2647 dbSNP
rs1410289885 2648 dbSNP
rs954323043 2650 dbSNP
rs1368303097 2651 dbSNP
rs1428641182 2655 dbSNP
rs549908154 2656 dbSNP
rs1332279275 2661 dbSNP
rs1434976816 2662 dbSNP
rs1158513853 2663 dbSNP
rs1284219935 2663 dbSNP
rs1471343552 2663 dbSNP
rs562577926 2663 dbSNP
rs60647232 2663 dbSNP
rs749916478 2663 dbSNP
rs1274756216 2664 dbSNP
rs1363144819 2665 dbSNP
rs1349136730 2670 dbSNP
rs1310444479 2678 dbSNP
rs1430792922 2679 dbSNP
rs372474938 2680 dbSNP
rs1163132090 2681 dbSNP
rs1295754502 2681 dbSNP
rs1019758375 2684 dbSNP
rs1414828947 2685 dbSNP
rs1223425439 2688 dbSNP
rs1292138546 2692 dbSNP
rs1449912446 2693 dbSNP
rs1219330126 2696 dbSNP
rs1158471572 2697 dbSNP
rs1246049706 2698 dbSNP
rs1475651059 2699 dbSNP
rs1471675120 2700 dbSNP
rs1190286134 2701 dbSNP
rs1388016407 2702 dbSNP
rs1448532965 2704 dbSNP
rs1200877656 2727 dbSNP
rs978587545 2728 dbSNP
rs1055960 2729 dbSNP
rs1392318543 2734 dbSNP
rs1219132029 2736 dbSNP
rs141117337 2739 dbSNP
rs928060623 2739 dbSNP
rs1227223537 2740 dbSNP
rs1323560004 2745 dbSNP
rs867347760 2750 dbSNP
rs990974858 2755 dbSNP
rs965477411 2757 dbSNP
rs1292100457 2763 dbSNP
rs1367536641 2763 dbSNP
rs978657897 2766 dbSNP
rs941613929 2769 dbSNP
rs1437833940 2775 dbSNP
rs558142084 2784 dbSNP
rs529135154 2785 dbSNP
rs1318971639 2797 dbSNP
rs924425572 2798 dbSNP
rs1414190135 2801 dbSNP
rs1160017649 2805 dbSNP
rs1364873937 2807 dbSNP
rs934387575 2808 dbSNP
rs1189212527 2810 dbSNP
rs1489367178 2817 dbSNP
rs1253228275 2820 dbSNP
rs548857713 2827 dbSNP
rs1463275968 2837 dbSNP
rs1038580792 2839 dbSNP
rs1239167035 2846 dbSNP
rs1312083376 2850 dbSNP
rs898835076 2867 dbSNP
rs989861744 2870 dbSNP
rs1368824996 2875 dbSNP
rs1320311427 2876 dbSNP
rs1433095606 2878 dbSNP
rs1286141630 2882 dbSNP
rs914214412 2884 dbSNP
rs948638493 2887 dbSNP
rs1321251106 2890 dbSNP
rs1044298499 2909 dbSNP
rs1354411742 2910 dbSNP
rs1173940354 2918 dbSNP
rs111773098 2919 dbSNP
rs1434687081 2919 dbSNP
rs1008713366 2920 dbSNP
rs1284975606 2924 dbSNP
rs1447234372 2926 dbSNP
rs770334876 2936 dbSNP
rs1465294794 2937 dbSNP
rs1210468642 2940 dbSNP
rs928461700 2942 dbSNP
rs10265704 2948 dbSNP
rs534298717 2950 dbSNP
rs1212774048 2961 dbSNP
rs1349251063 2968 dbSNP
rs1297261255 2971 dbSNP
rs550986404 2974 dbSNP
rs755163265 2976 dbSNP
rs1226682681 2977 dbSNP
rs1367577889 2978 dbSNP
rs10250187 2982 dbSNP
rs867588671 2984 dbSNP
rs978113987 2985 dbSNP
rs995981698 2988 dbSNP
rs536748122 2990 dbSNP
rs1167686514 3000 dbSNP
rs889760981 3001 dbSNP
rs1007097247 3012 dbSNP
rs1019859403 3020 dbSNP
rs1422882876 3028 dbSNP
rs1253388191 3031 dbSNP
rs557062075 3038 dbSNP
rs567747214 3039 dbSNP
rs1407996637 3040 dbSNP
rs1274598810 3050 dbSNP
rs916755084 3054 dbSNP
rs966013037 3057 dbSNP
rs1252103779 3058 dbSNP
rs1244255418 3060 dbSNP
rs1314887198 3061 dbSNP
rs755903200 3068 dbSNP
rs1355979145 3074 dbSNP
rs1307396349 3080 dbSNP
rs1388411919 3097 dbSNP
rs1453828292 3100 dbSNP
rs567493875 3104 dbSNP
rs1168293438 3107 dbSNP
rs1366385767 3112 dbSNP
rs777454244 3114 dbSNP
rs185478319 3117 dbSNP
rs188425105 3118 dbSNP
rs749194574 3125 dbSNP
rs1484327042 3126 dbSNP
rs1251622745 3132 dbSNP
rs1209646322 3133 dbSNP
rs1230205019 3136 dbSNP
rs191396047 3139 dbSNP
rs1267499280 3140 dbSNP
rs1328301424 3141 dbSNP
rs969680500 3148 dbSNP
rs1276747596 3155 dbSNP
rs1328650863 3157 dbSNP
rs1200809118 3159 dbSNP
rs928988959 3161 dbSNP
rs1337486764 3166 dbSNP
rs78009265 3169 dbSNP
rs1386046741 3171 dbSNP
rs928574809 3181 dbSNP
rs1251941213 3184 dbSNP
rs938577597 3186 dbSNP
rs1461502126 3189 dbSNP
rs1410492534 3193 dbSNP
rs1036894315 3195 dbSNP
rs1473831785 3198 dbSNP
rs1473266909 3199 dbSNP
rs1364915495 3205 dbSNP
rs1198559405 3209 dbSNP
rs944477501 3212 dbSNP
rs372732646 3223 dbSNP
rs1214627889 3225 dbSNP
rs1411852094 3227 dbSNP
rs900351416 3228 dbSNP
rs1266262555 3236 dbSNP
rs1230339358 3240 dbSNP
rs375971710 3244 dbSNP
rs1470554873 3245 dbSNP
rs1010729169 3251 dbSNP
rs1174682128 3257 dbSNP
rs1400464525 3259 dbSNP
rs1329197579 3266 dbSNP
rs1305359919 3279 dbSNP
rs1441114070 3285 dbSNP
rs559000831 3286 dbSNP
rs1387484061 3287 dbSNP
rs1044073037 3291 dbSNP
rs1317910630 3292 dbSNP
rs1414142170 3298 dbSNP
rs902408530 3307 dbSNP
rs999821999 3318 dbSNP
rs918387284 3324 dbSNP
rs575648424 3327 dbSNP
rs931433253 3339 dbSNP
rs1194675736 3342 dbSNP
rs1048424947 3344 dbSNP
rs889790792 3345 dbSNP
rs1006886089 3346 dbSNP
rs1041006199 3351 dbSNP
rs1286443688 3351 dbSNP
rs1349812912 3352 dbSNP
rs1284863595 3355 dbSNP
rs1233803511 3357 dbSNP
rs1342800705 3377 dbSNP
rs1282137923 3384 dbSNP
rs1012348097 3391 dbSNP
rs901454763 3393 dbSNP
rs1342557867 3394 dbSNP
rs1199574968 3395 dbSNP
rs1295015449 3399 dbSNP
rs1432277925 3403 dbSNP
rs1326577370 3412 dbSNP
rs544377780 3418 dbSNP
rs1031189365 3423 dbSNP
rs1413213107 3427 dbSNP
rs958409882 3434 dbSNP
rs1011340125 3438 dbSNP
rs778889970 3442 dbSNP
rs969791684 3450 dbSNP
rs1179401140 3451 dbSNP
rs1188574873 3456 dbSNP
rs1250354352 3466 dbSNP
rs1475866637 3469 dbSNP
rs1236917601 3472 dbSNP
rs1434277401 3472 dbSNP
rs773559851 3472 dbSNP
rs979786268 3476 dbSNP
rs928273475 3477 dbSNP
rs1211304511 3491 dbSNP
rs1341275949 3495 dbSNP
rs1376325728 3498 dbSNP
rs561474424 3503 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084074. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_SantaCruzAb HITS-CLIP data was present in GSM1084076. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_021167 | 3UTR | CCAUCUGCUAUGGACCCAUAAUAAGAGGCCUGUUGUAUAUGAAAUUGUCUAGAAUUCAGGUGCAGGUCUUUGCCGGUUAAGUAAGGGAGCAACACGUAAAAUGGGAGAGGAGUGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_021167 | 3UTR | GUAUAUGAAAUUGUCUAGAAUUCAGGUGCAGGUCUUUGCCGGUUAAGUAAGGGAGCAACACGUAAAAUGGGAGAGGAGUGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_021167 | 3UTR | CAUCUGCUAUGGACCCAUAAUAAGAGGCCUGUUGUAUAUGAAAUUGUCUAGAAUUCAGGUGCAGGUCUUUGCCGGUUAAGUAAGGGAGCAACACGUAAAAUGGGAGAGGAGUGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_021167 | 3UTR | CCCAUAAUAAGAGGCCUGUUGUAUAUGAAAUUGUCUAGAAUUCAGGUGCAGGUCUUUGCCGGUUAAGUAAGGGAGCAACACGUAAAAUGGGAGAGGAGUGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_021167 | 3UTR | ACCCUAAACCAUCUGCUAUGGACCCAUAAUAAGAGGCCUGUUGUAUAUGAAAUUGUCUAGAAUUCAGGUGCAGGUCUUUGCCGGUUAAGUAAGGGAGCAACACGUAAAAUGGGAGAGGAGUGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_021167 | 3UTR | UCAGGUGCAGGUCUUUGCCGGUUAAGUAAGGGAGCAACACGUAAAAUGGGAGAGGAGUGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1084074
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_SantaCruzAb
Location of target site ENST00000287957.3 | 3UTR | GAUGGAUCACUUGAGGUCAGGAGUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1084076
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_SigmaAb
Location of target site ENST00000287957.3 | 3UTR | UCAGGACCAGCCUGGCCAACAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
47 hsa-miR-3140-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT104285 CLDN12 claudin 12 2 2
MIRT255698 BHLHE40 basic helix-loop-helix family member e40 2 6
MIRT442182 SRP68 signal recognition particle 68 2 6
MIRT446582 FPR2 formyl peptide receptor 2 2 2
MIRT458038 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT463006 ZNF740 zinc finger protein 740 2 2
MIRT468535 SERPINH1 serpin family H member 1 2 4
MIRT468783 SCD stearoyl-CoA desaturase 2 2
MIRT482133 AKIRIN1 akirin 1 2 2
MIRT492057 TMEM59 transmembrane protein 59 2 2
MIRT492858 NRARP NOTCH regulated ankyrin repeat protein 2 2
MIRT497701 ARL6IP6 ADP ribosylation factor like GTPase 6 interacting protein 6 2 2
MIRT498157 FEM1C fem-1 homolog C 2 8
MIRT506244 PEX13 peroxisomal biogenesis factor 13 2 6
MIRT506291 PDPK1 3-phosphoinositide dependent protein kinase 1 2 4
MIRT534293 SKIL SKI like proto-oncogene 2 4
MIRT546463 SLC39A14 solute carrier family 39 member 14 2 2
MIRT565507 SP1 Sp1 transcription factor 2 2
MIRT572485 PRR14L proline rich 14 like 2 2
MIRT573398 DLC1 DLC1 Rho GTPase activating protein 2 2
MIRT610713 POU3F3 POU class 3 homeobox 3 2 2
MIRT611829 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 4
MIRT615701 NEGR1 neuronal growth regulator 1 2 2
MIRT621788 TMEM55A phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2 2
MIRT624127 HID1 HID1 domain containing 2 2
MIRT626051 PDE4C phosphodiesterase 4C 2 2
MIRT629867 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT630544 LGALS8 galectin 8 2 4
MIRT630952 PANK1 pantothenate kinase 1 2 2
MIRT634793 ENTHD1 ENTH domain containing 1 2 2
MIRT640130 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT652784 TEAD1 TEA domain transcription factor 1 2 2
MIRT654472 RANBP2 RAN binding protein 2 2 2
MIRT658126 FNBP1L formin binding protein 1 like 2 2
MIRT666203 SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 2 2
MIRT667083 OTOG otogelin 2 2
MIRT673472 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT693340 E2F2 E2F transcription factor 2 2 2
MIRT700796 PHTF2 putative homeodomain transcription factor 2 2 2
MIRT703115 GPRC5A G protein-coupled receptor class C group 5 member A 2 2
MIRT714839 SCAMP2 secretory carrier membrane protein 2 2 2
MIRT715244 DHODH dihydroorotate dehydrogenase (quinone) 2 2
MIRT717863 BICD2 BICD cargo adaptor 2 2 2
MIRT722764 SIRPB2 signal regulatory protein beta 2 2 2
MIRT723303 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
MIRT724049 GABRB1 gamma-aminobutyric acid type A receptor beta1 subunit 2 2
MIRT724219 RAB6B RAB6B, member RAS oncogene family 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-3140 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-3140-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-3140-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-3140-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

Error report submission