pre-miRNA Information
pre-miRNA hsa-mir-640   
Genomic Coordinates chr19: 19435063 - 19435158
Synonyms MIRN640, hsa-mir-640, MIR640
Description Homo sapiens miR-640 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-640
Sequence 61| AUGAUCCAGGAACCUGCCUCU |81
Evidence Experimental
Experiments RT-PCR
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30153378 1 COSMIC
COSN23015356 12 COSMIC
COSN30513185 19 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs111726405 1 dbSNP
rs765622881 2 dbSNP
rs1249744889 6 dbSNP
rs752995186 12 dbSNP
rs758746736 13 dbSNP
rs918887970 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SLC15A2   
Synonyms PEPT2
Description solute carrier family 15 member 2
Transcript NM_001145998   
Other Transcripts NM_021082   
Expression
Putative miRNA Targets on SLC15A2
3'UTR of SLC15A2
(miRNA target sites are highlighted)
>SLC15A2|NM_001145998|3'UTR
   1 TGACTCCCTAGATTCTGTCCTGACCCCAATTCCTGGCCCTGTCTTGAAGCATTTTTTTTCTTCTACTGGATTAGACAAGA
  81 GAGATAGCAGCATATCAGAGCTGATCTCCTCCACCTTTCTCCAATGACAGAAGTTCCAGGACTGGTTTTCCAGTACATCT
 161 TTAAACAAGGCCCCAGAGACTCTATGTCTGCCCGTCCATCAGTGAACTCATTAAAACTTGTGCAGTGTTGCTGGAGCTGG
 241 CCTGGTGTCTCCAAATGACCATGAAAATACACACGTATAATGGAGATCATTCTCTGTGGGTATGCAAAGTTATGGGAATT
 321 CCTTTATAGGTAACTGCCATTTAGGACTGATGGCCCTAATTTTTGAGGTGCTGATTTAGAGGCAAAATTGCAGAATAACA
 401 AAGAAATGGTATTTCAAGTTTTTTTTTTTATAAGCAATGTAATTATGCTATTCACAGGGGCCTCAAGAATTGGTATGTAT
 481 GATGTGATCTGGTCCAGCCAGGGCCTGGCTTGTCAGCTCTCTAGGTTTGATATGACTTTAGTAAATTTGTCAATATAGAT
 561 GGTAGGAAGCAGAATGCCATTTTATTAAAACACAGGAGAAGTTATATCTCTCTGATTATGATAGTATTTTATTTACTTAT
 641 CCAAACCCTCCTTTCTCAGTATGGATAGATCATGGAAACCAGATTAGAGATAGTAAGCATTAGTAAACATTGTTCTGGAG
 721 AACAGGAACAGGTGTAAGTTGTAGAAATCCTGAAGAGCCAGTCATTCTTTTACAGAGTACATTCTTCTTAGCCTCTATGG
 801 CGCTGGTCTATGCCCTTCAGTGAACAGTTGTATAAACAATAATTATAATTTGCAACCTTGTCTTGTCAACCTTGCTGATC
 881 CAGCTTTTTCTTATTATTACACCTTGTCTTGCTTATTGCAGCAAATATTCAATAACAACAATGTTTCTATAAGTCCAACT
 961 TCCTTTATTAATGTTTCCATTTAGCCTCAAAAATATCAAAGTAGTTCCTTTTTGATGTTGTTTTCCTGATTTACTTTTCC
1041 CATAAGTTTTAAATACCATTTCTGCCTTGAAGCCTAGAAATTTTCTTTTTATTCAAAAAAAGTTACATTAATGCTCTAGG
1121 TTTGAGGTTCTAAAATGGAAATGTCAATAGAGGAGCATGGTCCTATGTGAGGTTCCTATCAAAATTTGTGGGAGTAGGGA
1201 TGGTAGAGCATGAGGGTTTTGTTTGTGTATGTGTATGGTCATGAAAAAAAATTGAGAAACATTACCTCATACACAATGAA
1281 TGAATCAGAGGACAGACACGGGAATGGCACGACTGTGCAGTGTGTTACTAGGAAAAAAGTTCAGAATCACTGTTCTAGAG
1361 AGCTTCATTTCCATTGGTTTTAAAACATTATTCTCATGTAGAACAGTGTTGGGTCTCATACTGTTAATGTTAATACGTAA
1441 CAATGTTCATGTTAACAGGCACCTGTTAATATTAACAGATAATGTTACTGTTAACAGGTAAGAGAAATTGCTCTAAGTGC
1521 CCAAACTTTATATACTTCAGTTTTAATGACAAGCATTTCAGAAATATAAGAGCGGCAGCCAGACCAACCAGTTTTTCCAG
1601 ATATCTTGATGTGAACCTGACCCTACTCCTTTAGAAGACAGCCTGTTCATTTTTAAATAGCTTTAACCCAAACTGTTCTA
1681 TGACCATTGTTTCAAGAGACATTAACACAGTTCTGTAAATAGAAGTGTCTATGGACAAATAAGTTTGGGAAATGTGGCAT
1761 ACTGTATCCTTTTCTTAACATTTGCATATTAAAGACTCTGAGATATCCTGCAGTAAAGACACAAGATACCTTGTTTAAAT
1841 TAACATGTACGCTGCAGAACATTGGTTTGGAAAAAACTGTTGAGCAGTTCTTCCTTGTAAGTGCTGAGCTTCCTCTCTGA
1921 AACCTCCTACCATTGTTTTTTTTCCCCTGTAGCTAACAAGAATAAGTATAACAGCCGGCCAGGCACAGTGGCTCATGCCT
2001 GTAATCCCAGCACTTTGGGAGGCTGAGACAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTG
2081 AAACCGTGTCTCTACTAAAAGTACAAAAATTAGCCAGGTGTGATGGCAGGTGCCTGTAATCCCAGCTACTCGGGAGGCTG
2161 AAGCAGAAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAATGAGCCGAGATCACGCCATCACACTCTAGCCTGGGGGAC
2241 AAGAGTGAGACTTCATCTAAAAAAAAAAAGAAAAGAATATGTATACCCCCTTTTTCATGTGGCAGATGTTTAGCTATTTG
2321 GGGAGAACTTTCATGGCTCTTCCCTAATCATCAAGTATTCAAGGTAAAGATTCTCGGTTCCTGTAATGGTTCCTCACCAG
2401 GCATAATTTGTCCTTTTACCATCCTACTTTCTGTCTTCTGAAAAACATTCTTTATCTGAAATACAGCAATTAATATTAAG
2481 ATATCTTAATATGAAGTGCCTGGAGTCAAATATAACATTCCAAAGTAGTCTGACTGGAAGAACTAGCACCTGCCTTTCTT
2561 CAAACAATGCACTTCTGTTAATGCAGTGTAAGGTAACATGAGTTGTTTTTGGAAACTACATCATAATGTGGGCTTACATT
2641 CTAGCACTTATCACTTAATGACAGGGATACATTTGAGGAATGCATTGTTAGGCAATTTTGTCATTATGCAAACATCATAG
2721 AGTGTACTTACACAAACCTATGGTATAGCCTACTACACATCTAAGTTATATGGTATAGACTGTTTCTCCAGCTATATGGT
2801 GTAGACTGTTTCTCCTAGGCTACAAACCTGCACAGCATGTTACTGTATTAAATGCTGTAGGCAATTGTAACACAATGGTA
2881 TTTTTATACTTAAACATATCTAAACATAGAAACGGTACAAAAAACTTTACACATTATATAGATGTATCAAATTATTCATA
2961 TGTGCTCTGAAAATGTCTATATCTGTTATGTATCAATTTTTTAAAAAGTGAATGACATAATTCATTTGAAAAAATGTGGA
3041 CACACAAATTGGAAAAGAGGTATAAATGCAGTATTATAATCTAATGGGACCACCATCACATATTTGGTCTGTCATTGACT
3121 GAAACTGCAATATAGAGTTTTTCTTAACATTTGCATATTAAAGACTCTGACTATATATGG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' ucUCCGUCCAAGGACCUAGUa 5'
            || ||||    ||||||| 
Target 5' tgAGACAGG----TGGATCAc 3'
2024 - 2040 153.00 -15.70
2
miRNA  3' ucuccguccAAG--GACCUAGUa 5'
                   |||  ||||||:| 
Target 5' ttttttttcTTCTACTGGATTAg 3'
52 - 74 134.00 -9.20
3
miRNA  3' ucuccgUCCAAGGACCU-AGUa 5'
                | || |||||| ||| 
Target 5' aatatgAAGTGCCTGGAGTCAa 3'
2488 - 2509 127.00 -11.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30531632 3 COSMIC
COSN30118412 9 COSMIC
COSN30496403 33 COSMIC
COSN31531512 38 COSMIC
COSN19525165 42 COSMIC
COSN30509435 48 COSMIC
COSN28862370 60 COSMIC
COSN30480616 64 COSMIC
COSN1911263 78 COSMIC
COSN27306425 430 COSMIC
COSN8362064 468 COSMIC
COSN25388969 475 COSMIC
COSN20954535 1004 COSMIC
COSN1266278 1048 COSMIC
COSN26764335 1151 COSMIC
COSN20215654 1410 COSMIC
COSN9234267 1544 COSMIC
COSN21534312 1826 COSMIC
COSN14968512 1862 COSMIC
COSN26700485 1983 COSMIC
COSN25860221 2110 COSMIC
COSN1266280 2758 COSMIC
COSN16679159 3051 COSMIC
rs4285028 811 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1236805984 1 dbSNP
rs756335354 4 dbSNP
rs376337534 6 dbSNP
rs1920313 7 dbSNP
rs1451053926 10 dbSNP
rs768742539 15 dbSNP
rs778904221 17 dbSNP
rs748657034 22 dbSNP
rs772562183 24 dbSNP
rs527863503 25 dbSNP
rs1400209176 28 dbSNP
rs1318732225 39 dbSNP
rs1036035419 51 dbSNP
rs1159003988 52 dbSNP
rs755630690 52 dbSNP
rs777613903 52 dbSNP
rs761079256 53 dbSNP
rs1462696442 62 dbSNP
rs1452296032 68 dbSNP
rs1168264312 75 dbSNP
rs1379412210 76 dbSNP
rs79639971 77 dbSNP
rs1251436979 89 dbSNP
rs72551379 91 dbSNP
rs1465132599 97 dbSNP
rs1307392514 98 dbSNP
rs559591002 104 dbSNP
rs1203272659 122 dbSNP
rs528336333 126 dbSNP
rs114413458 130 dbSNP
rs1231970030 134 dbSNP
rs1008934377 141 dbSNP
rs778136112 142 dbSNP
rs4388019 147 dbSNP
rs867271060 151 dbSNP
rs893581232 152 dbSNP
rs1040894644 154 dbSNP
rs892558344 160 dbSNP
rs1010562370 162 dbSNP
rs1009943265 172 dbSNP
rs1366320797 175 dbSNP
rs1318118208 177 dbSNP
rs1022311674 181 dbSNP
rs1405054539 189 dbSNP
rs1253417062 191 dbSNP
rs904408185 194 dbSNP
rs1000141095 195 dbSNP
rs1204925057 199 dbSNP
rs1039398864 212 dbSNP
rs1450355791 223 dbSNP
rs900058598 227 dbSNP
rs60598279 236 dbSNP
rs1030210398 241 dbSNP
rs1256861017 246 dbSNP
rs1486946008 265 dbSNP
rs1199808264 272 dbSNP
rs138962289 275 dbSNP
rs1228642334 276 dbSNP
rs1180126117 285 dbSNP
rs529243087 290 dbSNP
rs550247692 301 dbSNP
rs1269963079 304 dbSNP
rs1429331658 308 dbSNP
rs992572181 314 dbSNP
rs1024442405 327 dbSNP
rs961825599 328 dbSNP
rs972117428 329 dbSNP
rs1414733604 338 dbSNP
rs920287985 350 dbSNP
rs1309984090 352 dbSNP
rs1311789235 381 dbSNP
rs1430623388 392 dbSNP
rs1419153575 394 dbSNP
rs1165939374 397 dbSNP
rs930883393 404 dbSNP
rs371138496 410 dbSNP
rs1186693710 412 dbSNP
rs910712167 417 dbSNP
rs370093110 419 dbSNP
rs748506460 419 dbSNP
rs944840959 419 dbSNP
rs991426947 419 dbSNP
rs1167761154 429 dbSNP
rs1270365951 430 dbSNP
rs530221312 433 dbSNP
rs1358846770 436 dbSNP
rs1285187555 440 dbSNP
rs762138549 446 dbSNP
rs766029633 449 dbSNP
rs969678400 451 dbSNP
rs942849972 453 dbSNP
rs756354407 463 dbSNP
rs1300564065 467 dbSNP
rs1400921275 474 dbSNP
rs982045798 485 dbSNP
rs1382417254 494 dbSNP
rs546837114 495 dbSNP
rs945492700 500 dbSNP
rs935132138 504 dbSNP
rs751250602 506 dbSNP
rs567058006 512 dbSNP
rs1469126846 520 dbSNP
rs914963083 522 dbSNP
rs946466056 525 dbSNP
rs903876589 526 dbSNP
rs1039346773 529 dbSNP
rs754443512 530 dbSNP
rs1034303774 532 dbSNP
rs1208719318 534 dbSNP
rs894406532 535 dbSNP
rs1486261869 542 dbSNP
rs780701550 547 dbSNP
rs752572222 548 dbSNP
rs1229563345 550 dbSNP
rs1014466184 552 dbSNP
rs1372639386 559 dbSNP
rs1277887636 561 dbSNP
rs1438839971 563 dbSNP
rs1024162050 565 dbSNP
rs1206993802 577 dbSNP
rs998293419 603 dbSNP
rs1390578705 611 dbSNP
rs114029015 619 dbSNP
rs1449095718 622 dbSNP
rs142177281 635 dbSNP
rs1004309059 651 dbSNP
rs867414732 672 dbSNP
rs756081770 710 dbSNP
rs1191372326 712 dbSNP
rs1017076416 713 dbSNP
rs1434807017 719 dbSNP
rs1173927785 723 dbSNP
rs951749059 724 dbSNP
rs1377025945 727 dbSNP
rs985767613 728 dbSNP
rs910764340 735 dbSNP
rs944976594 739 dbSNP
rs976625956 756 dbSNP
rs1321981957 759 dbSNP
rs1439008233 775 dbSNP
rs1367039301 781 dbSNP
rs1321020416 782 dbSNP
rs1429907340 782 dbSNP
rs1385920508 788 dbSNP
rs1343424676 794 dbSNP
rs914101768 798 dbSNP
rs945432555 799 dbSNP
rs1043858485 802 dbSNP
rs549316174 803 dbSNP
rs189331203 804 dbSNP
rs981871233 805 dbSNP
rs4285028 811 dbSNP
rs575030069 814 dbSNP
rs1055133387 816 dbSNP
rs1212876670 820 dbSNP
rs779247161 831 dbSNP
rs915079514 839 dbSNP
rs1232323939 840 dbSNP
rs946413831 841 dbSNP
rs1298041215 843 dbSNP
rs1014186215 844 dbSNP
rs1359614933 847 dbSNP
rs1045962231 852 dbSNP
rs1448697957 859 dbSNP
rs540732902 881 dbSNP
rs921051746 884 dbSNP
rs897681117 885 dbSNP
rs993645851 901 dbSNP
rs1169314392 903 dbSNP
rs1428229075 913 dbSNP
rs1247046285 922 dbSNP
rs1489313125 935 dbSNP
rs531812216 940 dbSNP
rs772806361 941 dbSNP
rs1208890872 944 dbSNP
rs1484158322 944 dbSNP
rs1419618374 948 dbSNP
rs887345416 949 dbSNP
rs1027326529 950 dbSNP
rs1233793163 959 dbSNP
rs1354798786 962 dbSNP
rs1290891901 968 dbSNP
rs1411055966 972 dbSNP
rs552847936 973 dbSNP
rs757417534 977 dbSNP
rs1297197984 978 dbSNP
rs573015969 987 dbSNP
rs544941945 997 dbSNP
rs1007155873 1002 dbSNP
rs1456347596 1005 dbSNP
rs1017235187 1007 dbSNP
rs1013080367 1015 dbSNP
rs1023033109 1017 dbSNP
rs907308038 1019 dbSNP
rs1417855454 1021 dbSNP
rs966251295 1021 dbSNP
rs1293310412 1027 dbSNP
rs1473582723 1030 dbSNP
rs565220482 1032 dbSNP
rs1251363766 1035 dbSNP
rs976382919 1038 dbSNP
rs530405533 1052 dbSNP
rs1482588043 1054 dbSNP
rs956568808 1057 dbSNP
rs988063612 1061 dbSNP
rs1214161698 1065 dbSNP
rs1022254893 1067 dbSNP
rs1271128466 1075 dbSNP
rs1230170909 1076 dbSNP
rs1286499537 1086 dbSNP
rs1305720953 1090 dbSNP
rs966940963 1098 dbSNP
rs746126829 1107 dbSNP
rs967871051 1112 dbSNP
rs778872054 1115 dbSNP
rs1257376544 1126 dbSNP
rs925320808 1127 dbSNP
rs1234003975 1128 dbSNP
rs975675382 1134 dbSNP
rs1394224689 1148 dbSNP
rs920994819 1153 dbSNP
rs192450987 1156 dbSNP
rs1364430257 1157 dbSNP
rs1055103497 1159 dbSNP
rs1417546671 1161 dbSNP
rs933753378 1165 dbSNP
rs1194515982 1166 dbSNP
rs1219043021 1170 dbSNP
rs1245974119 1187 dbSNP
rs185103906 1193 dbSNP
rs1184304493 1197 dbSNP
rs1248955282 1198 dbSNP
rs908227150 1199 dbSNP
rs1236336527 1203 dbSNP
rs1471948885 1207 dbSNP
rs1313443397 1208 dbSNP
rs1188086662 1211 dbSNP
rs1303616488 1221 dbSNP
rs1439738241 1228 dbSNP
rs949990896 1230 dbSNP
rs1415428430 1233 dbSNP
rs529693887 1235 dbSNP
rs1384400780 1238 dbSNP
rs1386389825 1240 dbSNP
rs1288361279 1241 dbSNP
rs1451645463 1244 dbSNP
rs939724354 1244 dbSNP
rs1045689374 1251 dbSNP
rs897743771 1260 dbSNP
rs1393013447 1262 dbSNP
rs775728795 1266 dbSNP
rs1447508414 1284 dbSNP
rs898777047 1286 dbSNP
rs1203332988 1288 dbSNP
rs1483919383 1293 dbSNP
rs1280459908 1295 dbSNP
rs546696556 1300 dbSNP
rs887498613 1301 dbSNP
rs1007291681 1302 dbSNP
rs948900426 1303 dbSNP
rs1044968254 1304 dbSNP
rs907259580 1311 dbSNP
rs1003370320 1320 dbSNP
rs555691789 1324 dbSNP
rs1313608584 1326 dbSNP
rs1434327137 1328 dbSNP
rs891793282 1338 dbSNP
rs1169875240 1340 dbSNP
rs965777475 1341 dbSNP
rs1011623786 1347 dbSNP
rs1425529691 1351 dbSNP
rs1257578309 1356 dbSNP
rs1022202672 1361 dbSNP
rs1484485533 1362 dbSNP
rs1377228455 1363 dbSNP
rs967971262 1367 dbSNP
rs998165928 1375 dbSNP
rs370769120 1379 dbSNP
rs1340443244 1385 dbSNP
rs760729736 1389 dbSNP
rs1225842387 1398 dbSNP
rs148590480 1405 dbSNP
rs955118062 1416 dbSNP
rs1207067135 1424 dbSNP
rs1272341844 1429 dbSNP
rs979573620 1436 dbSNP
rs141615516 1437 dbSNP
rs1210139768 1438 dbSNP
rs1471948760 1445 dbSNP
rs1238761977 1452 dbSNP
rs552570472 1453 dbSNP
rs1331080347 1458 dbSNP
rs990927312 1460 dbSNP
rs1410774798 1461 dbSNP
rs1395465506 1466 dbSNP
rs769190266 1476 dbSNP
rs1165990876 1484 dbSNP
rs1462940097 1489 dbSNP
rs908341053 1490 dbSNP
rs571776597 1492 dbSNP
rs949380076 1499 dbSNP
rs569616194 1509 dbSNP
rs1390427251 1514 dbSNP
rs1473907777 1515 dbSNP
rs1253380137 1520 dbSNP
rs1436910796 1522 dbSNP
rs1451672590 1523 dbSNP
rs538236066 1525 dbSNP
rs777050322 1529 dbSNP
rs762204947 1552 dbSNP
rs1159319843 1553 dbSNP
rs13860 1558 dbSNP
rs1274288655 1560 dbSNP
rs1920312 1565 dbSNP
rs1336238000 1567 dbSNP
rs1332718083 1568 dbSNP
rs1048866331 1571 dbSNP
rs746320200 1573 dbSNP
rs1281390953 1574 dbSNP
rs751162905 1575 dbSNP
rs759200218 1577 dbSNP
rs1326605082 1580 dbSNP
rs1357544839 1583 dbSNP
rs1394962352 1588 dbSNP
rs772490919 1602 dbSNP
rs1459845137 1610 dbSNP
rs928802868 1612 dbSNP
rs1158700061 1615 dbSNP
rs1469305400 1617 dbSNP
rs1230753141 1618 dbSNP
rs1270945525 1623 dbSNP
rs752200009 1630 dbSNP
rs150509976 1676 dbSNP
rs1254057123 1692 dbSNP
rs1038791210 1701 dbSNP
rs1295149098 1702 dbSNP
rs901599424 1709 dbSNP
rs1213582224 1711 dbSNP
rs1341355874 1726 dbSNP
rs780352121 1727 dbSNP
rs1136995 1744 dbSNP
rs1011571414 1745 dbSNP
rs1440147157 1746 dbSNP
rs1021059689 1753 dbSNP
rs1371418530 1756 dbSNP
rs1325028489 1767 dbSNP
rs868239053 1770 dbSNP
rs753762104 1790 dbSNP
rs1465984650 1798 dbSNP
rs1346957807 1802 dbSNP
rs1187048808 1803 dbSNP
rs1399554447 1813 dbSNP
rs1405189922 1814 dbSNP
rs1001146764 1821 dbSNP
rs1478622731 1823 dbSNP
rs540357170 1830 dbSNP
rs959567322 1851 dbSNP
rs1028276279 1852 dbSNP
rs1487789646 1853 dbSNP
rs189039600 1856 dbSNP
rs1217155373 1869 dbSNP
rs1423716772 1871 dbSNP
rs1008088057 1877 dbSNP
rs1413942577 1882 dbSNP
rs990894710 1895 dbSNP
rs1213256431 1897 dbSNP
rs769402552 1904 dbSNP
rs1302404625 1906 dbSNP
rs1231719512 1908 dbSNP
rs1363830566 1911 dbSNP
rs572938112 1914 dbSNP
rs1015287199 1916 dbSNP
rs1270644204 1923 dbSNP
rs1429973023 1929 dbSNP
rs1433244109 1935 dbSNP
rs961122335 1936 dbSNP
rs973684910 1936 dbSNP
rs559986684 1941 dbSNP
rs558418994 1944 dbSNP
rs1431749769 1946 dbSNP
rs980752931 1949 dbSNP
rs1187575482 1954 dbSNP
rs1475400947 1970 dbSNP
rs575153648 1973 dbSNP
rs1261103905 1974 dbSNP
rs1190231466 1975 dbSNP
rs1233735559 1977 dbSNP
rs181632804 1978 dbSNP
rs972729537 1980 dbSNP
rs918611120 1984 dbSNP
rs938829453 1986 dbSNP
rs1273495600 1998 dbSNP
rs560519467 1999 dbSNP
rs1053308542 2001 dbSNP
rs929205031 2002 dbSNP
rs1359856451 2005 dbSNP
rs757039060 2007 dbSNP
rs574386831 2008 dbSNP
rs374035960 2012 dbSNP
rs1354287420 2014 dbSNP
rs1268272950 2023 dbSNP
rs1330764779 2026 dbSNP
rs1310652154 2030 dbSNP
rs1463232391 2047 dbSNP
rs1356613874 2055 dbSNP
rs9856253 2057 dbSNP
rs1038848097 2058 dbSNP
rs900495615 2076 dbSNP
rs746034249 2078 dbSNP
rs560218637 2079 dbSNP
rs1256935978 2080 dbSNP
rs780477412 2081 dbSNP
rs891076016 2086 dbSNP
rs1007988896 2087 dbSNP
rs1042044029 2088 dbSNP
rs995222790 2090 dbSNP
rs532593042 2091 dbSNP
rs1159986049 2100 dbSNP
rs1333478177 2105 dbSNP
rs902201480 2117 dbSNP
rs1001115425 2121 dbSNP
rs1455813296 2122 dbSNP
rs147809456 2126 dbSNP
rs979814537 2131 dbSNP
rs1391761793 2137 dbSNP
rs895402495 2149 dbSNP
rs1398585184 2150 dbSNP
rs1036339436 2151 dbSNP
rs1325292481 2152 dbSNP
rs566390843 2153 dbSNP
rs1435752476 2164 dbSNP
rs564727531 2165 dbSNP
rs531998014 2183 dbSNP
rs1176854303 2184 dbSNP
rs867010572 2185 dbSNP
rs1254693585 2195 dbSNP
rs548923534 2200 dbSNP
rs762353138 2208 dbSNP
rs768655399 2209 dbSNP
rs973250645 2216 dbSNP
rs1025640227 2217 dbSNP
rs947570460 2221 dbSNP
rs1226069915 2224 dbSNP
rs1316998810 2229 dbSNP
rs952746343 2232 dbSNP
rs1237546013 2234 dbSNP
rs377397800 2234 dbSNP
rs1328402220 2236 dbSNP
rs984092105 2239 dbSNP
rs978839974 2247 dbSNP
rs909096278 2248 dbSNP
rs943310324 2250 dbSNP
rs1455360615 2252 dbSNP
rs1364484380 2258 dbSNP
rs113345338 2259 dbSNP
rs1350156712 2259 dbSNP
rs931965276 2260 dbSNP
rs974576100 2264 dbSNP
rs923128804 2268 dbSNP
rs777153408 2269 dbSNP
rs1451535417 2270 dbSNP
rs748622799 2272 dbSNP
rs186321233 2277 dbSNP
rs189679175 2279 dbSNP
rs770413756 2281 dbSNP
rs1053466357 2282 dbSNP
rs773737871 2284 dbSNP
rs1181556270 2287 dbSNP
rs535433796 2290 dbSNP
rs995337304 2295 dbSNP
rs1229054236 2304 dbSNP
rs1330900649 2305 dbSNP
rs895371334 2307 dbSNP
rs547552360 2309 dbSNP
rs1012531694 2319 dbSNP
rs1164773485 2330 dbSNP
rs1046540513 2338 dbSNP
rs1388354031 2345 dbSNP
rs570973048 2353 dbSNP
rs905640839 2364 dbSNP
rs1297717173 2372 dbSNP
rs1001579143 2376 dbSNP
rs906732174 2377 dbSNP
rs558673030 2382 dbSNP
rs1352296513 2386 dbSNP
rs1433811847 2389 dbSNP
rs1407382994 2390 dbSNP
rs1195199521 2391 dbSNP
rs1305693830 2397 dbSNP
rs770085522 2398 dbSNP
rs1260414329 2399 dbSNP
rs960245618 2400 dbSNP
rs773569375 2401 dbSNP
rs1486369281 2402 dbSNP
rs1280529568 2405 dbSNP
rs989055330 2407 dbSNP
rs763375102 2411 dbSNP
rs1344709070 2413 dbSNP
rs1254670524 2417 dbSNP
rs1020589500 2431 dbSNP
rs1327593035 2437 dbSNP
rs968857235 2454 dbSNP
rs978955232 2465 dbSNP
rs1357467529 2466 dbSNP
rs555732549 2472 dbSNP
rs921984233 2476 dbSNP
rs1282755765 2478 dbSNP
rs1005487645 2481 dbSNP
rs932105810 2494 dbSNP
rs1920311 2497 dbSNP
rs1462429855 2498 dbSNP
rs964587793 2499 dbSNP
rs1168463173 2510 dbSNP
rs911903543 2516 dbSNP
rs1257643262 2528 dbSNP
rs1186746883 2546 dbSNP
rs1920310 2547 dbSNP
rs767375557 2554 dbSNP
rs1254499838 2567 dbSNP
rs1198000439 2577 dbSNP
rs760202543 2583 dbSNP
rs180751034 2584 dbSNP
rs1257919673 2585 dbSNP
rs977960249 2587 dbSNP
rs1036905490 2593 dbSNP
rs1336998184 2594 dbSNP
rs1294034497 2598 dbSNP
rs1447557842 2599 dbSNP
rs1338994260 2606 dbSNP
rs923661196 2607 dbSNP
rs1391700259 2610 dbSNP
rs897100720 2616 dbSNP
rs554474411 2618 dbSNP
rs572102629 2621 dbSNP
rs1048237150 2642 dbSNP
rs1053435422 2644 dbSNP
rs1471605625 2648 dbSNP
rs139641465 2669 dbSNP
rs916272135 2673 dbSNP
rs752517456 2679 dbSNP
rs948326497 2684 dbSNP
rs1237992820 2685 dbSNP
rs116726781 2693 dbSNP
rs1185743791 2696 dbSNP
rs1470263418 2701 dbSNP
rs906789875 2713 dbSNP
rs994702642 2714 dbSNP
rs1443744586 2715 dbSNP
rs760615804 2718 dbSNP
rs764401126 2724 dbSNP
rs1354349563 2749 dbSNP
rs1281441413 2772 dbSNP
rs1240071532 2780 dbSNP
rs770085405 2781 dbSNP
rs1047246643 2787 dbSNP
rs1168998285 2790 dbSNP
rs1306872427 2792 dbSNP
rs374168152 2795 dbSNP
rs775841949 2797 dbSNP
rs1018214777 2802 dbSNP
rs538110514 2811 dbSNP
rs757277800 2813 dbSNP
rs1297103202 2816 dbSNP
rs1030629356 2831 dbSNP
rs1402348541 2834 dbSNP
rs557684452 2837 dbSNP
rs765061553 2841 dbSNP
rs1203477183 2844 dbSNP
rs978299901 2846 dbSNP
rs576833949 2856 dbSNP
rs545917825 2858 dbSNP
rs923798567 2859 dbSNP
rs1247743869 2862 dbSNP
rs1381589267 2865 dbSNP
rs1221508654 2866 dbSNP
rs1449899353 2868 dbSNP
rs577727865 2876 dbSNP
rs1286480996 2879 dbSNP
rs750243872 2882 dbSNP
rs189813159 2890 dbSNP
rs1300332527 2894 dbSNP
rs570746718 2900 dbSNP
rs1029163004 2902 dbSNP
rs766034587 2902 dbSNP
rs1236142240 2907 dbSNP
rs78573588 2914 dbSNP
rs1434264197 2915 dbSNP
rs1228360649 2917 dbSNP
rs139263922 2919 dbSNP
rs987564008 2933 dbSNP
rs1418709814 2935 dbSNP
rs780389434 2937 dbSNP
rs1175142572 2939 dbSNP
rs912015172 2942 dbSNP
rs916239558 2950 dbSNP
rs961999121 2951 dbSNP
rs1191093762 2952 dbSNP
rs1477355635 2966 dbSNP
rs199705222 2973 dbSNP
rs200774493 2975 dbSNP
rs1255657525 2976 dbSNP
rs947675293 2976 dbSNP
rs972067340 2980 dbSNP
rs1488008457 2992 dbSNP
rs1284080614 2995 dbSNP
rs754056587 3003 dbSNP
rs981800591 3003 dbSNP
rs918474412 3004 dbSNP
rs1217391993 3005 dbSNP
rs1188957433 3007 dbSNP
rs928180346 3008 dbSNP
rs1391859003 3010 dbSNP
rs1270700985 3029 dbSNP
rs930258056 3035 dbSNP
rs757426996 3037 dbSNP
rs1337805893 3043 dbSNP
rs1314290553 3046 dbSNP
rs1415063244 3046 dbSNP
rs1360089069 3047 dbSNP
rs112532686 3050 dbSNP
rs1378157058 3053 dbSNP
rs1467069780 3057 dbSNP
rs1300582038 3065 dbSNP
rs1404882602 3069 dbSNP
rs888640384 3070 dbSNP
rs1477511465 3077 dbSNP
rs1261171518 3078 dbSNP
rs927141654 3091 dbSNP
rs1322928557 3092 dbSNP
rs941446659 3094 dbSNP
rs1483733292 3095 dbSNP
rs376667157 3101 dbSNP
rs145263025 3103 dbSNP
rs76033877 3112 dbSNP
rs1309051372 3126 dbSNP
rs2689275 3136 dbSNP
rs998555143 3137 dbSNP
rs895598713 3139 dbSNP
rs1029676313 3149 dbSNP
rs1217971423 3150 dbSNP
rs890355808 3151 dbSNP
rs1041424510 3158 dbSNP
rs1330083469 3165 dbSNP
rs999471664 3172 dbSNP
rs1210868726 3176 dbSNP
rs1249641606 3182 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' ucUCCGUCCAAGGACCUAGUa 5'
            || ||||    ||||||| 
Target 5' -gAGACAGG----UGGAUCAc 3'
1 - 16
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000489711.1 | 3UTR | ACAGGUGGAUCACCUGAGGUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084073
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_AbnovaAb
Location of target site ENST00000489711.1 | 3UTR | GAGACAGGUGGAUCACCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.549 2.7e-3 0.508 5.6e-3 24 Click to see details
GSE27834 Pluripotent stem cells 0.493 2.6e-2 0.406 5.9e-2 16 Click to see details
GSE19783 ER+ ER+ breast cancer -0.439 2.6e-2 -0.510 1.1e-2 20 Click to see details
GSE21849 B cell lymphoma 0.363 2.6e-2 0.438 8.7e-3 29 Click to see details
GSE17498 Multiple myeloma 0.229 7.8e-2 0.130 2.1e-1 40 Click to see details
GSE42095 Differentiated embryonic stem cells -0.291 8.9e-2 0.000 5.0e-1 23 Click to see details
GSE14794 Lymphoblastoid cells 0.101 1.7e-1 0.096 1.8e-1 90 Click to see details
GSE28260 Renal cortex and medulla 0.249 2.1e-1 0.227 2.3e-1 13 Click to see details
GSE38226 Liver fibrosis -0.144 2.7e-1 -0.225 1.6e-1 21 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.123 2.8e-1 -0.138 2.6e-1 25 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.123 3.0e-1 -0.026 4.6e-1 20 Click to see details
GSE26953 Aortic valvular endothelial cells 0.109 3.1e-1 0.017 4.7e-1 24 Click to see details
GSE17306 Multiple myeloma -0.069 3.2e-1 0.057 3.5e-1 49 Click to see details
GSE21687 Ependynoma primary tumors -0.047 3.6e-1 -0.049 3.5e-1 64 Click to see details
GSE19536 Breast cancer -0.036 3.6e-1 0.011 4.6e-1 100 Click to see details
GSE32688 Pancreatic cancer 0.054 3.8e-1 0.103 2.9e-1 32 Click to see details
GSE19350 CNS germ cell tumors 0.071 4.1e-1 0.580 2.4e-2 12 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.019 4.6e-1 0.051 4.0e-1 25 Click to see details
GSE19783 ER- ER- breast cancer 0.004 4.9e-1 0.062 2.9e-1 79 Click to see details
GSE19783 ER- ER- breast cancer 0.004 4.9e-1 0.062 2.9e-1 79 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
194 hsa-miR-640 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT097121 TNPO1 transportin 1 2 2
MIRT115090 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 4
MIRT204603 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT204634 MOB4 MOB family member 4, phocein 2 8
MIRT344451 MTRNR2L1 MT-RNR2-like 1 2 2
MIRT405772 EIF5 eukaryotic translation initiation factor 5 2 2
MIRT445876 SENP6 SUMO1/sentrin specific peptidase 6 2 2
MIRT497418 FAM46A family with sequence similarity 46 member A 2 2
MIRT504394 HMX2 H6 family homeobox 2 2 4
MIRT504691 SLCO2B1 solute carrier organic anion transporter family member 2B1 2 8
MIRT512386 MTRNR2L3 MT-RNR2-like 3 2 6
MIRT513003 MAN1A2 mannosidase alpha class 1A member 2 2 2
MIRT513084 USP9X ubiquitin specific peptidase 9, X-linked 2 2
MIRT519122 ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2 2
MIRT523836 F2RL1 F2R like trypsin receptor 1 2 2
MIRT565356 TMCC1 transmembrane and coiled-coil domain family 1 2 2
MIRT575895 Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 2 3
MIRT576894 Poteg POTE ankyrin domain family, member G 2 2
MIRT613780 RPS6 ribosomal protein S6 2 2
MIRT613934 POLR3A RNA polymerase III subunit A 2 2
MIRT614348 LOH12CR1 BLOC-1 related complex subunit 5 2 2
MIRT614534 NOA1 nitric oxide associated 1 2 2
MIRT617019 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT618247 MANEAL mannosidase endo-alpha like 2 2
MIRT619051 TTC4 tetratricopeptide repeat domain 4 2 2
MIRT619442 ZNF517 zinc finger protein 517 2 2
MIRT619723 FPR2 formyl peptide receptor 2 2 2
MIRT620179 TRIM72 tripartite motif containing 72 2 2
MIRT620370 ANKRD62 ankyrin repeat domain 62 2 2
MIRT621263 RTN2 reticulon 2 2 2
MIRT621463 APOH apolipoprotein H 2 2
MIRT621571 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT621683 TSPYL1 TSPY like 1 2 2
MIRT622866 PDE7A phosphodiesterase 7A 2 2
MIRT624669 ARHGEF39 Rho guanine nucleotide exchange factor 39 2 2
MIRT625607 ZNF84 zinc finger protein 84 2 2
MIRT626111 IL23R interleukin 23 receptor 2 2
MIRT628380 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 2 2
MIRT628553 MELK maternal embryonic leucine zipper kinase 2 2
MIRT628671 C2orf72 chromosome 2 open reading frame 72 2 2
MIRT628747 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT628776 TMEM154 transmembrane protein 154 2 2
MIRT628918 ZNF430 zinc finger protein 430 2 2
MIRT629174 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT629209 C12orf66 chromosome 12 open reading frame 66 2 2
MIRT629267 SLC5A8 solute carrier family 5 member 8 2 2
MIRT629498 AS3MT arsenite methyltransferase 2 2
MIRT629665 USP1 ubiquitin specific peptidase 1 2 2
MIRT629760 STK25 serine/threonine kinase 25 2 2
MIRT630899 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT631105 SLC15A2 solute carrier family 15 member 2 2 2
MIRT631112 ATCAY ATCAY, caytaxin 2 2
MIRT631450 DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 2 2
MIRT631505 FFAR4 free fatty acid receptor 4 2 2
MIRT631580 ITGAL integrin subunit alpha L 2 2
MIRT631836 CMBL carboxymethylenebutenolidase homolog 2 2
MIRT632342 SWSAP1 SWIM-type zinc finger 7 associated protein 1 2 2
MIRT633214 ZNF584 zinc finger protein 584 2 2
MIRT633223 ZNF43 zinc finger protein 43 2 2
MIRT633480 ARIH2OS ariadne RBR E3 ubiquitin protein ligase 2 opposite strand 2 2
MIRT633511 LRRC27 leucine rich repeat containing 27 2 2
MIRT633615 CWF19L1 CWF19 like 1, cell cycle control (S. pombe) 2 2
MIRT633652 SLC28A1 solute carrier family 28 member 1 2 2
MIRT633677 ZNF576 zinc finger protein 576 2 2
MIRT634196 TMOD2 tropomodulin 2 2 4
MIRT634388 PLSCR1 phospholipid scramblase 1 2 2
MIRT635817 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT635962 TTC31 tetratricopeptide repeat domain 31 2 2
MIRT636114 YPEL1 yippee like 1 2 2
MIRT636164 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT636768 CLUAP1 clusterin associated protein 1 2 2
MIRT637092 CXorf23 BCLAF1 and THRAP3 family member 3 2 2
MIRT637316 FAM9B family with sequence similarity 9 member B 2 2
MIRT637540 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT637628 ZNF431 zinc finger protein 431 2 2
MIRT637826 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT637945 IVD isovaleryl-CoA dehydrogenase 2 2
MIRT637968 IRF1 interferon regulatory factor 1 2 2
MIRT638321 RNF11 ring finger protein 11 2 2
MIRT638386 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT639244 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT642608 APOPT1 apoptogenic 1, mitochondrial 2 2
MIRT642793 SLC1A5 solute carrier family 1 member 5 2 2
MIRT643847 LACTB lactamase beta 2 4
MIRT644705 ZNF321P zinc finger protein 321, pseudogene 2 2
MIRT645148 DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 2 3
MIRT646671 CCDC69 coiled-coil domain containing 69 2 2
MIRT647780 ASB8 ankyrin repeat and SOCS box containing 8 2 2
MIRT648554 WDR92 WD repeat domain 92 2 2
MIRT648990 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT649099 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 2
MIRT650141 ZNF426 zinc finger protein 426 2 2
MIRT650791 GSR glutathione-disulfide reductase 2 2
MIRT654967 PLEKHA2 pleckstrin homology domain containing A2 2 2
MIRT655099 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT655516 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 2
MIRT656289 METTL14 methyltransferase like 14 2 2
MIRT656497 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT657074 JPH2 junctophilin 2 2 2
MIRT657314 HOOK3 hook microtubule tethering protein 3 2 2
MIRT657419 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 2 4
MIRT659032 DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2 2
MIRT659535 CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2 2
MIRT661532 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT662029 FUT2 fucosyltransferase 2 2 2
MIRT663206 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT663357 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT663557 CCR6 C-C motif chemokine receptor 6 2 2
MIRT663650 POLM DNA polymerase mu 2 2
MIRT663694 ABHD17B abhydrolase domain containing 17B 2 2
MIRT664370 CYB5A cytochrome b5 type A 2 2
MIRT664783 LIAS lipoic acid synthetase 2 4
MIRT665561 TXNL1 thioredoxin like 1 2 2
MIRT665950 TAOK1 TAO kinase 1 2 2
MIRT667338 MSANTD3 Myb/SANT DNA binding domain containing 3 2 2
MIRT667804 ITIH5 inter-alpha-trypsin inhibitor heavy chain family member 5 2 2
MIRT668804 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT669470 ARPC2 actin related protein 2/3 complex subunit 2 2 2
MIRT669599 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT669806 STOML1 stomatin like 1 2 2
MIRT669944 FBXL2 F-box and leucine rich repeat protein 2 2 2
MIRT670292 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT670381 EMP2 epithelial membrane protein 2 2 2
MIRT670481 DCUN1D2 defective in cullin neddylation 1 domain containing 2 2 2
MIRT670531 KIF1C kinesin family member 1C 2 4
MIRT670565 GLTP glycolipid transfer protein 2 2
MIRT670603 NPHP1 nephrocystin 1 2 2
MIRT670880 CYTIP cytohesin 1 interacting protein 2 2
MIRT670931 LIPG lipase G, endothelial type 2 2
MIRT671261 MTRNR2L5 MT-RNR2-like 5 2 2
MIRT671794 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT671897 GBP4 guanylate binding protein 4 2 2
MIRT672000 SLC35F6 solute carrier family 35 member F6 2 4
MIRT672074 KIR3DX1 killer cell immunoglobulin like receptor, three Ig domains X1 2 2
MIRT672319 C9orf3 chromosome 9 open reading frame 3 2 2
MIRT672853 C22orf29 retrotransposon Gag like 10 2 2
MIRT673395 WNT7B Wnt family member 7B 2 2
MIRT673537 DEGS1 delta 4-desaturase, sphingolipid 1 2 2
MIRT674285 ZNF724P zinc finger protein 724 2 2
MIRT674494 TIRAP TIR domain containing adaptor protein 2 2
MIRT675460 NUBPL nucleotide binding protein like 2 2
MIRT675569 TRIP11 thyroid hormone receptor interactor 11 2 2
MIRT676068 TIMM50 translocase of inner mitochondrial membrane 50 2 2
MIRT676254 PBOV1 prostate and breast cancer overexpressed 1 2 2
MIRT676377 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT676758 SNX2 sorting nexin 2 2 2
MIRT676773 NPHS1 NPHS1, nephrin 2 2
MIRT676874 ENSA endosulfine alpha 2 2
MIRT676918 KLHDC8A kelch domain containing 8A 2 2
MIRT676944 S1PR3 sphingosine-1-phosphate receptor 3 2 2
MIRT676957 HFE hemochromatosis 2 2
MIRT676967 RNF19B ring finger protein 19B 2 2
MIRT676972 ZNF708 zinc finger protein 708 2 2
MIRT677042 ZNF34 zinc finger protein 34 2 2
MIRT677070 VMAC vimentin type intermediate filament associated coiled-coil protein 2 2
MIRT677093 MFSD11 major facilitator superfamily domain containing 11 2 4
MIRT677134 P2RX7 purinergic receptor P2X 7 2 2
MIRT677179 ZNF786 zinc finger protein 786 2 2
MIRT677228 C15orf40 chromosome 15 open reading frame 40 2 2
MIRT677320 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 2
MIRT677455 PDLIM3 PDZ and LIM domain 3 2 2
MIRT677809 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT677937 ZNF519 zinc finger protein 519 2 2
MIRT678063 UBN2 ubinuclein 2 2 4
MIRT678072 EIF2A eukaryotic translation initiation factor 2A 2 2
MIRT678252 FXN frataxin 2 2
MIRT678315 FBLIM1 filamin binding LIM protein 1 2 2
MIRT678367 XIAP X-linked inhibitor of apoptosis 2 4
MIRT678372 RNF115 ring finger protein 115 2 2
MIRT678410 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678518 ZNF347 zinc finger protein 347 2 2
MIRT678566 CDK4 cyclin dependent kinase 4 2 2
MIRT678580 PPP1R3B protein phosphatase 1 regulatory subunit 3B 2 2
MIRT678820 PDE6A phosphodiesterase 6A 2 2
MIRT678917 XPOT exportin for tRNA 2 2
MIRT679217 MAN2A2 mannosidase alpha class 2A member 2 2 2
MIRT679437 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT679595 HILPDA hypoxia inducible lipid droplet associated 2 2
MIRT679755 TLR6 toll like receptor 6 2 2
MIRT679800 APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A 2 2
MIRT680057 CD96 CD96 molecule 2 2
MIRT680116 CCDC30 coiled-coil domain containing 30 2 4
MIRT680181 ZNF554 zinc finger protein 554 2 2
MIRT680439 WDR12 WD repeat domain 12 2 2
MIRT680789 ZNF578 zinc finger protein 578 2 2
MIRT692464 APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 2 2
MIRT702952 HIP1 huntingtin interacting protein 1 2 2
MIRT706016 ZSCAN2 zinc finger and SCAN domain containing 2 2 2
MIRT706032 F2R coagulation factor II thrombin receptor 2 2
MIRT706135 MTRNR2L10 MT-RNR2-like 10 2 2
MIRT706394 HAS2 hyaluronan synthase 2 2 2
MIRT713293 DCP2 decapping mRNA 2 2 2
MIRT716583 BRAP BRCA1 associated protein 2 2
MIRT720433 C19orf47 chromosome 19 open reading frame 47 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-640 Paclitaxel 36314 NSC125973 approved resistant High Ovarian Cancer tissue and cell line (SKOV3)
hsa-miR-640 Cetuximab resistant High Colon Cancer cell line
hsa-miR-640 Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (WM266) (1uM)
hsa-miR-640 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (WM266) (1uM)
hsa-miR-640 Mitoxantrone 4212 NSC279836 approved resistant High Breast Cancer cell line (BT-20, BT-474, BT-549, CAMA-1, HCC1143, HCC1395, HCC1569, HCC1806, HCC-1937, HCC1954, HCC202, HCC38, HCC70, Hs578T, MCF-7, MDA-MB-175VII, MDA-MB-231, MDA-MB-361, MDA-MB-415, MDA-MB-436, MDA-MB-468, SKBR3, T47D, UACC812, EVSA-T, MPE-600 , SK-BR-
hsa-miR-640 Sorafenib 216239 NSC747971 approved sensitive Low Clear Cell Renal Cell Carcinoma cell line (786-O)
hsa-mir-640 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-640 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-640 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-640 Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-640 Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-640 Tamoxifen 2733525 NSC180973 approved sensitive cell line (TamR8)
hsa-miR-640 Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-640 Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-640 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

Error report submission