pre-miRNA Information
pre-miRNA hsa-mir-1245a   
Genomic Coordinates chr2: 188978092 - 188978161
Description Homo sapiens miR-1245a stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-1245a
Sequence 45| AAGUGAUCUAAAGGCCUACAU |65
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN31562560 15 COSMIC
COSN26581044 19 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs906938680 2 dbSNP
rs1159117523 3 dbSNP
rs780486044 6 dbSNP
rs771479866 17 dbSNP
rs1002976932 18 dbSNP
rs1428029219 19 dbSNP
Putative Targets

Gene Information
Gene Symbol FAM9B   
Synonyms TEX39B
Description family with sequence similarity 9 member B
Transcript NM_205849   
Expression
Putative miRNA Targets on FAM9B
3'UTR of FAM9B
(miRNA target sites are highlighted)
>FAM9B|NM_205849|3'UTR
   1 ACATGTTTTTAAATAAAATCATGTCAGAACTCTTTTGGAAAAGTTGGCACTTACCCAGTTGTCTCTTCAACCTCTGTTAT
  81 TCTGATGACTGAAGAAAGAACTTGAACCTATGTTATATGATACAAGCACAACTTGAGCTACAGTAAACTACATGACAGTG
 161 TTTTGATAATTGTTGTATAAATCGGTATAGCTCCTCTGTCACTCGTCTGTTAAATGCCAGACCTCGTTTCTATGATCTGT
 241 TGAATGAATCCTAGACACTTCTGTGAGAAAGCAGGGATTGCATAGTTATGTACACGGTCAATTAAATTTTAACATTAAAG
 321 ATAATTTAGATTTCGATTTGGCCTCTGTGGATTTGTATCAGTTCCAAAAATGTAGAAAGCACAGGCATAGAAAAGTACAT
 401 TTTTCTCTAATAAAAGAAGACAATATCTGCTGGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGG
 481 GAGTGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTGCTAAAAATACCAAAA
 561 TTACCCGGGCGTGGTGGCACGCACGTGTAGTTCCAGCTACTCAGGAAGCTGAGGCAGGAGGATCTCTTGAACCCGGGAGT
 641 TGGAGGTTGCAGTAAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTTTCTCAGAAAACAAGA
 721 AGAAGAAGACAAAAGCTATCTTATCTGTGCGTTCTTTTGTATTTACTCATTAGGATAAAGAGGCAATTCCAATGAAAGTA
 801 GGACTTCAAAAAATAGATATACTCTATGGCCATATCAAAATTATTAAAAGCACCTTACTGTCTGTGTTCTTAAAAAAAAT
 881 TATACTGCTGTAAATGATTAAGGCAACTGAGCAAGATATATTAATATCAGTGCTGAGCCACTGGTTTGTGGGTATGTCAT
 961 TTCCACAGACATCAAAATGCTATTTAGTTTGTTTTGGTCCATCATTCAATGATACCTCCCCTTAGAATTGAATGAAAGCA
1041 TTTTGTTAACATTTATGTATGCTTACAATTATTTCACATCTGTGGCAAGGTAAATTTTGTAGAGTGCTTTGTTTATCCAG
1121 TTTAATATTCGTGGATTATGTGGAAGTTTATATGGACATCTAAAAACTTGAATGATG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' uacaUCCGGAAAUCUAGUGAa 5'
              |||    |:||||||| 
Target 5' gccgAGGGGAGTGGATCACTt 3'
473 - 493 149.00 -14.70
2
miRNA  3' uaCAUCCGGAA-------AUCUA-GUGAa 5'
            ||||| |||       ||||| :||| 
Target 5' aaGTAGGACTTCAAAAAATAGATATACTc 3'
796 - 824 119.00 -11.51
3
miRNA  3' uacaUCCGGAAAUCUAGUGAa 5'
              ||||    :|||| || 
Target 5' gctgAGGCAGGAGGATCTCTt 3'
608 - 628 117.00 -11.70
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1266735096 3 dbSNP
rs767895428 4 dbSNP
rs1194719420 5 dbSNP
rs1420096129 14 dbSNP
rs1409806772 21 dbSNP
rs1160547196 31 dbSNP
rs759735838 32 dbSNP
rs751821791 33 dbSNP
rs1188803402 34 dbSNP
rs371492822 37 dbSNP
rs765528348 39 dbSNP
rs1474366507 44 dbSNP
rs763029165 46 dbSNP
rs748282640 54 dbSNP
rs1167118453 63 dbSNP
rs1369247713 72 dbSNP
rs1020955929 74 dbSNP
rs1296518992 76 dbSNP
rs1373009318 78 dbSNP
rs1410917889 101 dbSNP
rs1312661077 110 dbSNP
rs774118045 113 dbSNP
rs1353913424 120 dbSNP
rs201668923 124 dbSNP
rs768644471 127 dbSNP
rs1292068421 131 dbSNP
rs1321918542 134 dbSNP
rs1226128571 135 dbSNP
rs1224169113 137 dbSNP
rs1356683401 139 dbSNP
rs1483996339 160 dbSNP
rs1205731109 161 dbSNP
rs748978602 163 dbSNP
rs1484595578 171 dbSNP
rs779881569 182 dbSNP
rs1183348182 200 dbSNP
rs1009543665 206 dbSNP
rs1215129889 209 dbSNP
rs766940658 230 dbSNP
rs1363985737 231 dbSNP
rs893831347 274 dbSNP
rs1430987077 277 dbSNP
rs1268260084 289 dbSNP
rs374113647 290 dbSNP
rs1032221832 294 dbSNP
rs1007923571 297 dbSNP
rs5979007 310 dbSNP
rs745558632 311 dbSNP
rs888951735 331 dbSNP
rs780656931 332 dbSNP
rs1294805946 339 dbSNP
rs1315155911 342 dbSNP
rs1343616094 344 dbSNP
rs1228462635 355 dbSNP
rs933057371 359 dbSNP
rs1310362298 364 dbSNP
rs897549316 367 dbSNP
rs1036087725 368 dbSNP
rs763606123 379 dbSNP
rs941659117 387 dbSNP
rs908876504 390 dbSNP
rs1450224801 395 dbSNP
rs376156664 400 dbSNP
rs756705546 401 dbSNP
rs1416596537 403 dbSNP
rs1164130121 409 dbSNP
rs775047145 415 dbSNP
rs938304676 418 dbSNP
rs541769682 440 dbSNP
rs1185231905 441 dbSNP
rs926795240 446 dbSNP
rs187832815 448 dbSNP
rs970899749 460 dbSNP
rs1302047096 465 dbSNP
rs1201161443 476 dbSNP
rs1489702082 493 dbSNP
rs1220811797 505 dbSNP
rs1279106658 521 dbSNP
rs1316068233 536 dbSNP
rs1206568981 553 dbSNP
rs765591225 554 dbSNP
rs1465513800 558 dbSNP
rs1213212398 566 dbSNP
rs755518796 567 dbSNP
rs988227074 572 dbSNP
rs1192229253 574 dbSNP
rs1407862313 581 dbSNP
rs754152382 582 dbSNP
rs957990648 585 dbSNP
rs182527389 591 dbSNP
rs1032796868 612 dbSNP
rs1438553481 616 dbSNP
rs141248887 630 dbSNP
rs1372492365 635 dbSNP
rs1226424772 643 dbSNP
rs1289972127 646 dbSNP
rs1330085528 646 dbSNP
rs759460615 647 dbSNP
rs1287837925 648 dbSNP
rs1453447127 651 dbSNP
rs773522594 654 dbSNP
rs1222356709 669 dbSNP
rs1407042249 672 dbSNP
rs767884055 673 dbSNP
rs1413073672 675 dbSNP
rs776704467 677 dbSNP
rs1162229794 679 dbSNP
rs1411155382 686 dbSNP
rs953446626 688 dbSNP
rs1030260149 690 dbSNP
rs1353925405 697 dbSNP
rs1407862822 701 dbSNP
rs1309650377 731 dbSNP
rs1350826777 740 dbSNP
rs1232428786 741 dbSNP
rs1293078659 745 dbSNP
rs897663907 746 dbSNP
rs1443041225 752 dbSNP
rs1356288192 754 dbSNP
rs1340666629 755 dbSNP
rs1207870684 764 dbSNP
rs1168995018 774 dbSNP
rs1485579132 775 dbSNP
rs1036034906 794 dbSNP
rs1465519210 795 dbSNP
rs770996827 801 dbSNP
rs761734132 802 dbSNP
rs1430490206 811 dbSNP
rs370614808 825 dbSNP
rs190476968 830 dbSNP
rs1427760110 831 dbSNP
rs1005957421 833 dbSNP
rs1479284739 836 dbSNP
rs1395307040 842 dbSNP
rs887451342 855 dbSNP
rs768465435 856 dbSNP
rs1055893442 857 dbSNP
rs1230673398 865 dbSNP
rs938265699 865 dbSNP
rs926841294 872 dbSNP
rs1347789260 874 dbSNP
rs1199160553 875 dbSNP
rs1281101212 877 dbSNP
rs1443795662 885 dbSNP
rs113971839 896 dbSNP
rs1247002529 897 dbSNP
rs1447174588 906 dbSNP
rs1189932017 914 dbSNP
rs112984214 915 dbSNP
rs1390771266 920 dbSNP
rs747027010 921 dbSNP
rs1170599960 926 dbSNP
rs1404037170 932 dbSNP
rs1415279392 942 dbSNP
rs1344830546 946 dbSNP
rs1320201204 959 dbSNP
rs1386690550 961 dbSNP
rs74802101 985 dbSNP
rs757092822 986 dbSNP
rs74621556 987 dbSNP
rs1298409950 992 dbSNP
rs1370931376 994 dbSNP
rs1231631499 995 dbSNP
rs1276991656 1006 dbSNP
rs1203787855 1009 dbSNP
rs1324142181 1014 dbSNP
rs914081001 1025 dbSNP
rs988220710 1037 dbSNP
rs1210067869 1038 dbSNP
rs958386779 1043 dbSNP
rs1432553527 1048 dbSNP
rs1264850852 1050 dbSNP
rs1221455372 1059 dbSNP
rs1322498079 1070 dbSNP
rs1478257753 1076 dbSNP
rs1158147474 1080 dbSNP
rs866566232 1088 dbSNP
rs925293626 1097 dbSNP
rs749313222 1105 dbSNP
rs1300856097 1123 dbSNP
rs1392141489 1127 dbSNP
rs35296101 1128 dbSNP
rs986507844 1132 dbSNP
rs953422335 1134 dbSNP
rs1030622591 1155 dbSNP
rs997393747 1156 dbSNP
rs1296500224 1157 dbSNP
rs1286777190 1163 dbSNP
rs1326658124 1165 dbSNP
rs961842864 1183 dbSNP
rs775234153 1188 dbSNP
rs769624257 1189 dbSNP
rs1207528654 1190 dbSNP
rs1269444001 1191 dbSNP
rs1407458778 1195 dbSNP
rs887553799 1198 dbSNP
rs1055563453 1199 dbSNP
rs1001585686 1224 dbSNP
rs1473706240 1225 dbSNP
rs906871635 1236 dbSNP
rs1339200702 1237 dbSNP
rs1368097116 1242 dbSNP
rs12393315 1243 dbSNP
rs1165073718 1252 dbSNP
rs1377382709 1256 dbSNP
rs1046650945 1263 dbSNP
rs1420476645 1266 dbSNP
rs949651245 1270 dbSNP
rs892619764 1271 dbSNP
rs370909720 1273 dbSNP
rs1307324869 1280 dbSNP
rs1177465675 1281 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084041. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep1 HITS-CLIP data was present in GSM1084068. RNA binding protein: AGO2. Condition:CLIP_noemetine_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' uacauccggaaAUCUAGUGAa 5'
                     |:||||||| 
Target 5' ---------agUGGAUCACUu 3'
1 - 12
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084041
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep1
Location of target site ENST00000362066.3 | 3UTR | GAGUGGAUCACUUGAGGUCAGGAGUUUGAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084068
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SigmaAb
Location of target site ENST00000362066.3 | 3UTR | AGUGGAUCACUUGAGGUCAGGAGUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
BLCA -0.923 0.13 -1.000 0.5 3 Click to see details
UCEC -0.013 0.5 0.125 0.46 3 Click to see details
UCEC -0.013 0.5 0.125 0.46 3 Click to see details
UCEC -0.013 0.5 0.125 0.46 3 Click to see details
UCEC -0.013 0.5 0.125 0.46 3 Click to see details
UCEC -0.013 0.5 0.125 0.46 3 Click to see details
UCEC -0.013 0.5 0.125 0.46 3 Click to see details
UCEC -0.013 0.5 0.125 0.46 3 Click to see details
109 hsa-miR-1245a Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT006574 BRCA2 BRCA2, DNA repair associated 2 1
MIRT055432 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 2
MIRT063879 RASSF8 Ras association domain family member 8 2 6
MIRT077025 WIPF2 WAS/WASL interacting protein family member 2 2 2
MIRT095775 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT099172 MAP3K4 mitogen-activated protein kinase kinase kinase 4 2 2
MIRT175616 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT456518 LYPLAL1 lysophospholipase like 1 2 2
MIRT464457 UGCG UDP-glucose ceramide glucosyltransferase 2 2
MIRT465747 TMPPE transmembrane protein with metallophosphoesterase domain 2 2
MIRT468257 SFXN4 sideroflexin 4 2 2
MIRT469216 RICTOR RPTOR independent companion of MTOR complex 2 2 2
MIRT472045 NPAT nuclear protein, coactivator of histone transcription 2 2
MIRT481795 APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 2 2
MIRT500154 CREBBP CREB binding protein 2 2
MIRT506514 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 4
MIRT506915 KBTBD8 kelch repeat and BTB domain containing 8 2 6
MIRT513901 GRB10 growth factor receptor bound protein 10 2 6
MIRT519128 ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2 2
MIRT528121 FOXH1 forkhead box H1 2 2
MIRT528942 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT540580 CEP89 centrosomal protein 89 2 2
MIRT545858 ZNF264 zinc finger protein 264 2 4
MIRT547147 PGM3 phosphoglucomutase 3 2 2
MIRT547434 MED4 mediator complex subunit 4 2 2
MIRT554650 ROBO1 roundabout guidance receptor 1 2 2
MIRT558524 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT559762 ABHD5 abhydrolase domain containing 5 2 2
MIRT560438 GOLGA7B golgin A7 family member B 2 2
MIRT561974 LRRC59 leucine rich repeat containing 59 2 2
MIRT562442 DDIT4 DNA damage inducible transcript 4 2 2
MIRT563489 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT568265 BMP2K BMP2 inducible kinase 2 2
MIRT572522 KIAA0232 KIAA0232 2 2
MIRT612801 LSM14A LSM14A, mRNA processing body assembly factor 2 2
MIRT621533 ZNF507 zinc finger protein 507 2 2
MIRT625205 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT625615 ZNF84 zinc finger protein 84 2 2
MIRT629215 C12orf66 chromosome 12 open reading frame 66 2 2
MIRT629509 AS3MT arsenite methyltransferase 2 2
MIRT629769 STK25 serine/threonine kinase 25 2 2
MIRT630908 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT632508 RAB13 RAB13, member RAS oncogene family 2 2
MIRT636871 ARSE arylsulfatase E (chondrodysplasia punctata 1) 2 2
MIRT637106 CXorf23 BCLAF1 and THRAP3 family member 3 2 2
MIRT637332 FAM9B family with sequence similarity 9 member B 2 2
MIRT637553 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT637639 ZNF431 zinc finger protein 431 2 2
MIRT637836 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT638326 RNF11 ring finger protein 11 2 2
MIRT638393 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT642450 CLUAP1 clusterin associated protein 1 2 2
MIRT642616 APOPT1 apoptogenic 1, mitochondrial 2 2
MIRT643133 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT644324 NFKBID NFKB inhibitor delta 2 2
MIRT645150 DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 2 2
MIRT645673 ADK adenosine kinase 2 2
MIRT646091 MGST3 microsomal glutathione S-transferase 3 2 2
MIRT646858 SLC35E4 solute carrier family 35 member E4 2 2
MIRT650153 ZNF426 zinc finger protein 426 2 2
MIRT652483 TMEM181 transmembrane protein 181 2 2
MIRT653790 SIRPA signal regulatory protein alpha 2 2
MIRT655526 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 2
MIRT657077 JPH2 junctophilin 2 2 2
MIRT657322 HOOK3 hook microtubule tethering protein 3 2 2
MIRT662036 FUT2 fucosyltransferase 2 2 2
MIRT662322 ADM2 adrenomedullin 2 2 2
MIRT663211 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT663559 CCR6 C-C motif chemokine receptor 6 2 2
MIRT663937 ZNF554 zinc finger protein 554 2 2
MIRT664689 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT664709 PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 2
MIRT665291 ZFP14 ZFP14 zinc finger protein 2 2
MIRT665572 TXNL1 thioredoxin like 1 2 2
MIRT667068 PAOX polyamine oxidase 2 2
MIRT667304 MYO5A myosin VA 2 2
MIRT667442 METTL14 methyltransferase like 14 2 2
MIRT668048 GTPBP10 GTP binding protein 10 2 2
MIRT669604 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT671088 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT674361 SLC35E3 solute carrier family 35 member E3 2 2
MIRT674962 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT676394 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT676819 AGMAT agmatinase 2 2
MIRT676891 ENSA endosulfine alpha 2 2
MIRT677059 ZNF34 zinc finger protein 34 2 2
MIRT678424 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678735 SRCAP Snf2 related CREBBP activator protein 2 2
MIRT678930 XPOT exportin for tRNA 2 2
MIRT678954 MYADM myeloid associated differentiation marker 2 2
MIRT679228 MAN2A2 mannosidase alpha class 2A member 2 2 2
MIRT679765 TLR6 toll like receptor 6 2 2
MIRT681992 HRH4 histamine receptor H4 2 2
MIRT687405 NSUN4 NOP2/Sun RNA methyltransferase family member 4 2 2
MIRT694570 RBMXL1 RNA binding motif protein, X-linked like 1 2 2
MIRT698449 TM4SF1 transmembrane 4 L six family member 1 2 2
MIRT706406 HAS2 hyaluronan synthase 2 2 2
MIRT706582 ZNF432 zinc finger protein 432 2 2
MIRT706838 VHLL VHL like 2 2
MIRT706909 DVL3 dishevelled segment polarity protein 3 2 2
MIRT707052 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT708583 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT708988 CABP4 calcium binding protein 4 2 2
MIRT713041 ADRA2B adrenoceptor alpha 2B 2 2
MIRT713731 SUCO SUN domain containing ossification factor 2 2
MIRT714968 RAB21 RAB21, member RAS oncogene family 2 2
MIRT717485 PDE4DIP phosphodiesterase 4D interacting protein 2 2
MIRT722826 KLK2 kallikrein related peptidase 2 2 2
MIRT723305 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-1245a Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (M14) (500nM)
hsa-miR-1245a Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (M14) (500nM)
hsa-miR-1245a Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (M14) (1uM)
hsa-miR-1245a Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (M14) (1uM)
hsa-miR-1245a Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-1245a Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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