miRTarBase - #MIRT641242


—
pre-miRNA Information
pre-miRNA hsa-mir-1303   
Genomic Coordinates chr5: 154685776 - 154685861
Synonyms MIRN1303, hsa-mir-1303, MIR1303
Description Homo sapiens miR-1303 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-1303
Sequence 52| UUUAGAGACGGGGUCUUGCUCU |73
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 5 + 154685830 23291724, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs370437195 6 dbSNP
rs1195001383 7 dbSNP
rs546614687 8 dbSNP
rs762579883 9 dbSNP
rs766041486 10 dbSNP
rs751079975 12 dbSNP
rs888516744 13 dbSNP
rs566454487 14 dbSNP
rs766973220 15 dbSNP
rs1474274822 17 dbSNP
rs753222192 18 dbSNP
rs1230907999 19 dbSNP
rs756552638 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CENPN   
Synonyms BM039, C16orf60, CENP-N, ICEN32
Description centromere protein N
Transcript NM_001100624   
Other Transcripts NM_001100625 , NM_018455   
Expression
Putative miRNA Targets on CENPN
3'UTR of CENPN
(miRNA target sites are highlighted)		 
>CENPN|NM_001100624|3'UTR
   1 GACGTGCGTGGTTTCTTAAGCACAGCTCCTCCTTCTTGATATTGCACATGCACTTCAGTTCATGGCTAGCTGTATAGCTT
  81 CCGTCTGTAAACTTGTATTTTCAAGAATCCTTGGTATTGAATTTTTAGAAATGCTCACATAATTGTTGGGACTGATTCAT
 161 TCCTCCACGATATGCCTCCTCTCTCTGATATCCTGCTAACTGTAGCCGTTGTGGCATTTGAGATGACAGGACATATATAT
 241 ATATGGCCCCACACTTGACCTTGAGTGCCTGAATGCTCTGAAATCAAGCATATGGCACAGCGCTCAAGACTTTTGGGTTT
 321 GTGTCCTTTTTTCTATGGCTGTCTCTTCTCAATTCTGGAGAGGTCTGGTTCCAGTGGCTGGTTTCCAGGGATTGATTCTT
 401 AAGCTCTGGATCACAGAGAGAAGCAACAAGGAACTATACTCAACTCAAAACTTTTTAGGAGAATCATGAAATTGGTCTAT
 481 TCAAAGGATGGAGTTGAGTCCATTCTGTTATTGTTGCAAGAGGTTGCATATTTGGTGAGTCAGTTATATAAAATAGTGTT
 561 CTTATTGTAAATATGATACTTCTCATAATCTATTTTATCATGTGTATAACATTCAAACTGACAAATATATTGACTTATGA
 641 ATAAAGGTGTCAAAAAACTGGCACATCAGTTAATTTTGATCAAAGTACTTCAGTGATCATCACTAAATACCCTATCTTTT
 721 TAAAAATTTTTTCCTTTCTAATTTTTTATTTCTTTATTTATTTATTGAGACAGGGTCTCACTGTGTCACCCAAGCTGGAG
 801 TGCAGTGGCATGATCATGGCTCACTGCAGCCTGGACCTCCCAGGCTCAAGTGATCCTTCCACCTCAGCCTCCCGAATAGC
 881 TGGGATTACAGACGCGCTCCATCCTGCCCAGCTAATTTTTTTTTTGTTTGTTTTTTGTTTTTTGAGACAAGTCTCCTTCT
 961 ATCGCCCAGGCTGGAGTGCAATGGCACAATCTTGGCTCCCTGCAACCTCTGCCTCCTGGGTTGAAGAGATTCTCCTGCCT
1041 CAGCCTCTGAGTAGCTGGGACTACAGGCCTGCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTC
1121 TCCATGTTGCCCAGGCTGATCTCAAACTCCTGGGCTCAAGCAATCTGCCCATTTTAGCCTCCTAAAATGCTGGGATTATA
1201 GGAGTGTATTAGTCTATTCTCATGCTGCTAATAAAGATACCTAAGACTGGGTAATTCACAAAGGAAAGAGGCTTAACTGA
1281 CGCACATTTCCACGTGGCCAGGGAGGCCTCACAATCATGGTGGAAGGCAAATGAGAAGCAAAGTCATGTCTTACATGGCG
1361 GCAGGCAAGAGAGCTTGTGCAGGGAAACTCCCATTTATAAAACCACCAGAGCTCATGAAACTTATTCACTACCATGAGAA
1441 TAGTATGGGGGAAATCGTTCCCATGACTCAAGTATCTCCACCTGGCCCTGCCCTTGTCACATGGGGGTTATTACAATTCA
1521 AGGTGACACTTGTGTGGAGACACAGCCAAACCATATCACAGGCATGAGCTACCACGCCCGCCAGCATGTCTTTTTTAAAC
1601 ATTTTAAAATCTATTCTTTATCTTGTTTCAGAGAGGATTTGGAGTTACAGAAACACATTAGACTGGGCATGGTGGCTCAC
1681 ACTTGTAATCCCAGCACTTCAGGAGGTTTCTCCTAGTGTACTCTCACACTTCTGATACCAGATATGTGGGGGAGGGGGTT
1761 TCCCCCACACATTAAGCAAGTGTGAAACATGATATAGAAAAATGACTTCACTCTGGGCCGGGTGTAGTGGCTCACGCCTG
1841 TAATCCTAGCACTTTGGGAAGCCGAGGTGGGCAGATCACCCGAGGTCAGGAGTTCGAGACCAGCCTAGCCAACATGGCAA
1921 AACCTTGTCTCTACTAAAAATAGAAAAATTAGTTGGGGGTAGTGGCAGCCGCCTGTAATCCCAGCTATTCGAGAGGCTGA
2001 GGCAGGAGAACTGGTTGAACCGGGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACTCTAGCCTGGGTGACA
2081 GAGTGAAACTCTGCCTCAAAAAATAAAATAAAGGCCAGGCATGGTGGCTCACGCCTATAATCCCAGCACTTTCAGAGGCC
2161 AAGGCAGGTGGGTCACAAGGTCAAGAGTTTGAGACTAGCCTTAGCAACATGGTGAAGGTGAACCCCGACTCTACTAAAAA
2241 TACAAAAATTAGCTGGGCCTGGTGGTGTGCACCTGTAATCCCAGCTACTTAGGAGGCTGAGGCAGGAGAATCGCTTGAAC
2321 CCGGGAGACATAGGTTGCAGTGAGCCGAGACTGCACCACTGCACTCCAGCCTAGGTGACAGAGTGAGACTCCATCTTAAA
2401 AAATAAATAAATAAAATAAAATAAATGACATCACTTTGGTTCAGAGCTCTAAAATGGAGGGAGGAAGCCATTCTAAAAAG
2481 GACTCCCTACATGACCTGCAACTTGAAAAAAAATTAAAAGCTCCAAAAAAAAAACAATACAGGAGCTTACCTTGAACCTT
2561 TGAATTGGGCCAAATTGCGATGACCACTGCATCCTGGAAAATTTTATTTCACCAGCACTACAACTCCTCAACAGCACCAA
2641 CCAATAAACTATGGATTTTTGTACTAAGCCAGTTGCCTCTTTCAAAACAACTTGTCAACTTGTCTAATCACCCTCAGCTT
2721 TTTTTAAAAACCCCTCCTCTACCCTCTCTCTTCAGAACACAAGTGGCTTCTAGCTGAATCTGTCTCCCAAATTGCAATTC
2801 CTAAGACCTCAATAAAAACACCTTGTCTTGCTGCAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucUCGUUCUGGGGCAGAGAUuu 5'
            :|||| |||::|||||||  
Target 5' atGGCAAAACCTTGTCTCTAct 3'
 1914 - 1935 160.00 -21.10
2 
miRNA  3' ucuCGU-UCUGGGGCAGAGAUUu 5'
             |:| || ::|||||| ||| 
Target 5' gctGTATAGCTTCCGTCTGTAAa 3'
 69 - 91 135.00 -16.20
3 
miRNA  3' ucucGUUCUG-GGGCAGAGAUUu 5'
              :| | | ||: |||||:| 
Target 5' acgaTATGCCTCCTCTCTCTGAt 3'
 167 - 189 134.00 -12.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26970392 5 COSMIC
COSN1710520 8 COSMIC
COSN15330787 9 COSMIC
COSN30110430 21 COSMIC
COSN30624867 27 COSMIC
COSN30120122 52 COSMIC
COSN30125658 80 COSMIC
COSN30142120 82 COSMIC
COSN31536598 92 COSMIC
COSN30167786 120 COSMIC
COSN30193727 138 COSMIC
COSN30761350 173 COSMIC
COSN29752862 563 COSMIC
COSN29753855 575 COSMIC
COSN18860920 600 COSMIC
COSN31961242 1072 COSMIC
COSN9444076 1444 COSMIC
COSN7274649 1473 COSMIC
COSN26095136 1960 COSMIC
COSN6096193 2120 COSMIC
COSN27508724 2535 COSMIC
COSN7274650 2791 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs749732364 3 dbSNP
rs377398346 4 dbSNP
rs779123055 5 dbSNP
rs1279551008 6 dbSNP
rs1342738996 7 dbSNP
rs201073061 8 dbSNP
rs71400134 9 dbSNP
rs1436346572 18 dbSNP
rs760274680 29 dbSNP
rs770496287 30 dbSNP
rs1218851920 32 dbSNP
rs747794371 32 dbSNP
rs1479194409 33 dbSNP
rs776739470 34 dbSNP
rs370635113 35 dbSNP
rs1452500536 36 dbSNP
rs765130647 37 dbSNP
rs752403628 38 dbSNP
rs1031233884 44 dbSNP
rs958010480 45 dbSNP
rs1393689333 46 dbSNP
rs370371110 47 dbSNP
rs767624758 48 dbSNP
rs1351214079 49 dbSNP
rs374449585 52 dbSNP
rs756194517 53 dbSNP
rs1158891369 55 dbSNP
rs1413484200 56 dbSNP
rs1422480905 58 dbSNP
rs1028892021 69 dbSNP
rs1478054997 71 dbSNP
rs1328663589 73 dbSNP
rs953029561 83 dbSNP
rs184980265 84 dbSNP
rs1287114821 86 dbSNP
rs911681289 88 dbSNP
rs1280969561 94 dbSNP
rs1339933569 98 dbSNP
rs1391852795 103 dbSNP
rs35552248 107 dbSNP
rs762312389 110 dbSNP
rs972279124 137 dbSNP
rs1342151317 140 dbSNP
rs905643383 147 dbSNP
rs1001280689 149 dbSNP
rs1446860808 150 dbSNP
rs1032679883 155 dbSNP
rs1177745941 157 dbSNP
rs920746095 159 dbSNP
rs930782258 164 dbSNP
rs1169178700 169 dbSNP
rs1010169351 170 dbSNP
rs1264378683 174 dbSNP
rs1181691381 175 dbSNP
rs1482463859 176 dbSNP
rs1020647072 179 dbSNP
rs763682606 180 dbSNP
rs774119939 188 dbSNP
rs955306472 189 dbSNP
rs1256167280 193 dbSNP
rs575031262 194 dbSNP
rs950061730 198 dbSNP
rs1319846513 199 dbSNP
rs1260033206 200 dbSNP
rs1046136332 208 dbSNP
rs903291528 209 dbSNP
rs139018356 223 dbSNP
rs1452837956 233 dbSNP
rs146994969 233 dbSNP
rs753886051 233 dbSNP
rs1398926198 236 dbSNP
rs1181730392 239 dbSNP
rs1254516523 245 dbSNP
rs1018106245 247 dbSNP
rs1328629692 247 dbSNP
rs934728651 248 dbSNP
rs964767797 249 dbSNP
rs1164688741 250 dbSNP
rs974764209 251 dbSNP
rs1054517007 253 dbSNP
rs1416339527 258 dbSNP
rs563261288 264 dbSNP
rs1010706604 270 dbSNP
rs761854121 272 dbSNP
rs1028924508 282 dbSNP
rs1200653216 287 dbSNP
rs530412757 289 dbSNP
rs1167952364 299 dbSNP
rs1243959852 301 dbSNP
rs750280202 302 dbSNP
rs755904650 303 dbSNP
rs937080337 304 dbSNP
rs961851947 306 dbSNP
rs189444666 314 dbSNP
rs1302121785 315 dbSNP
rs73595485 318 dbSNP
rs1293476607 321 dbSNP
rs1456782849 322 dbSNP
rs1019942695 330 dbSNP
rs1293655001 332 dbSNP
rs1340171137 337 dbSNP
rs891078554 339 dbSNP
rs1008107544 342 dbSNP
rs1378740251 344 dbSNP
rs1216977449 346 dbSNP
rs1275226081 347 dbSNP
rs1419806193 351 dbSNP
rs1018532087 353 dbSNP
rs1487441459 359 dbSNP
rs1267122374 361 dbSNP
rs1223001993 362 dbSNP
rs1352713704 363 dbSNP
rs1283513178 367 dbSNP
rs963818773 369 dbSNP
rs1209502874 377 dbSNP
rs967152187 383 dbSNP
rs1299946401 385 dbSNP
rs1385619910 388 dbSNP
rs1370418816 395 dbSNP
rs952217540 397 dbSNP
rs974817917 405 dbSNP
rs991584270 406 dbSNP
rs1359004402 407 dbSNP
rs1160695453 410 dbSNP
rs916198776 413 dbSNP
rs1377172231 415 dbSNP
rs1027718066 416 dbSNP
rs1434950299 428 dbSNP
rs1271047721 436 dbSNP
rs950300566 440 dbSNP
rs766525845 442 dbSNP
rs981494464 444 dbSNP
rs952116711 449 dbSNP
rs180956450 461 dbSNP
rs1283537120 466 dbSNP
rs1218380731 468 dbSNP
rs934654946 478 dbSNP
rs1255033131 480 dbSNP
rs1182832813 484 dbSNP
rs1054949440 488 dbSNP
rs1230483816 491 dbSNP
rs185768959 492 dbSNP
rs1284546092 509 dbSNP
rs893191227 514 dbSNP
rs1399870475 523 dbSNP
rs946564408 531 dbSNP
rs1477302615 532 dbSNP
rs117167180 536 dbSNP
rs889057711 542 dbSNP
rs1009219305 556 dbSNP
rs1467701352 565 dbSNP
rs1018836846 574 dbSNP
rs1430007805 576 dbSNP
rs1421028132 579 dbSNP
rs542693603 585 dbSNP
rs1428663067 588 dbSNP
rs548305052 591 dbSNP
rs1357404695 592 dbSNP
rs1436469274 593 dbSNP
rs1313287457 600 dbSNP
rs1359599339 611 dbSNP
rs937466664 613 dbSNP
rs1054617097 615 dbSNP
rs1398388595 616 dbSNP
rs1228698165 623 dbSNP
rs570066534 626 dbSNP
rs114145162 628 dbSNP
rs1397939596 631 dbSNP
rs890764686 635 dbSNP
rs1330708993 639 dbSNP
rs1464114553 648 dbSNP
rs1008574992 652 dbSNP
rs1421445787 652 dbSNP
rs189640488 654 dbSNP
rs1475650465 660 dbSNP
rs1218776106 665 dbSNP
rs1367613826 678 dbSNP
rs1184965142 682 dbSNP
rs1018168510 683 dbSNP
rs1027368791 684 dbSNP
rs1243241848 685 dbSNP
rs951791269 690 dbSNP
rs570601078 693 dbSNP
rs1456066924 694 dbSNP
rs899743084 697 dbSNP
rs995327466 704 dbSNP
rs1356100574 712 dbSNP
rs1282749002 717 dbSNP
rs1299248342 722 dbSNP
rs760335617 722 dbSNP
rs866940626 723 dbSNP
rs1026766868 727 dbSNP
rs971509475 728 dbSNP
rs1330824466 729 dbSNP
rs1235591045 730 dbSNP
rs1015345372 734 dbSNP
rs1389783606 734 dbSNP
rs1285766842 741 dbSNP
rs1161190603 749 dbSNP
rs534894072 751 dbSNP
rs971392239 753 dbSNP
rs982118191 755 dbSNP
rs181901938 757 dbSNP
rs958938557 761 dbSNP
rs1234048536 774 dbSNP
rs1183207716 776 dbSNP
rs1288327239 791 dbSNP
rs924847288 791 dbSNP
rs1243544943 795 dbSNP
rs914707917 799 dbSNP
rs1360616219 800 dbSNP
rs186195469 801 dbSNP
rs1238167462 803 dbSNP
rs1375623148 812 dbSNP
rs1041438507 820 dbSNP
rs1442863522 823 dbSNP
rs912234671 825 dbSNP
rs1321474368 828 dbSNP
rs943742742 836 dbSNP
rs990157868 845 dbSNP
rs1365902448 847 dbSNP
rs914696811 853 dbSNP
rs932702402 855 dbSNP
rs1039763052 856 dbSNP
rs899794248 870 dbSNP
rs868460094 874 dbSNP
rs995379798 875 dbSNP
rs1379613195 880 dbSNP
rs2602429 894 dbSNP
rs886906539 896 dbSNP
rs557352256 897 dbSNP
rs1214758221 898 dbSNP
rs1318905168 899 dbSNP
rs944534022 902 dbSNP
rs575249897 910 dbSNP
rs10713656 916 dbSNP
rs1342956765 916 dbSNP
rs368114422 916 dbSNP
rs397855227 916 dbSNP
rs536506124 916 dbSNP
rs544313511 916 dbSNP
rs201156241 917 dbSNP
rs190718987 923 dbSNP
rs201180655 923 dbSNP
rs1373206767 927 dbSNP
rs1235668972 930 dbSNP
rs1309260235 931 dbSNP
rs1346643045 931 dbSNP
rs1159377784 933 dbSNP
rs564177418 940 dbSNP
rs958948513 945 dbSNP
rs572927334 949 dbSNP
rs1179212075 954 dbSNP
rs1048711192 956 dbSNP
rs1423380483 957 dbSNP
rs1192012686 961 dbSNP
rs147211540 962 dbSNP
rs148693197 964 dbSNP
rs183296979 965 dbSNP
rs1250603330 966 dbSNP
rs1469473659 970 dbSNP
rs1225298698 974 dbSNP
rs1310250749 975 dbSNP
rs1277456417 977 dbSNP
rs529061484 979 dbSNP
rs754971119 982 dbSNP
rs912344168 984 dbSNP
rs971974864 985 dbSNP
rs1003007158 990 dbSNP
rs1237549100 996 dbSNP
rs1446745411 998 dbSNP
rs550879147 1006 dbSNP
rs1338067796 1008 dbSNP
rs562636027 1011 dbSNP
rs1400263955 1017 dbSNP
rs956312655 1020 dbSNP
rs990171304 1021 dbSNP
rs1420585620 1024 dbSNP
rs1048267642 1033 dbSNP
rs866298557 1035 dbSNP
rs1471906023 1039 dbSNP
rs367718458 1039 dbSNP
rs1162857581 1052 dbSNP
rs1204433465 1054 dbSNP
rs1457369784 1056 dbSNP
rs939891836 1057 dbSNP
rs954001244 1065 dbSNP
rs1202290842 1068 dbSNP
rs1309040239 1069 dbSNP
rs985563549 1070 dbSNP
rs142142027 1072 dbSNP
rs1380188728 1075 dbSNP
rs1330734590 1078 dbSNP
rs186594846 1081 dbSNP
rs1040200477 1082 dbSNP
rs748579699 1089 dbSNP
rs759030408 1091 dbSNP
rs1378815051 1102 dbSNP
rs1164573757 1111 dbSNP
rs1226960957 1113 dbSNP
rs368242597 1114 dbSNP
rs534760866 1115 dbSNP
rs1048745004 1116 dbSNP
rs1236367029 1125 dbSNP
rs1011854552 1127 dbSNP
rs1021910075 1130 dbSNP
rs887462323 1132 dbSNP
rs968022499 1137 dbSNP
rs1357003523 1140 dbSNP
rs1336467490 1142 dbSNP
rs1293567385 1147 dbSNP
rs1246182981 1151 dbSNP
rs546763339 1155 dbSNP
rs1020198470 1164 dbSNP
rs1012496055 1168 dbSNP
rs1436035799 1172 dbSNP
rs1183834335 1173 dbSNP
rs1233243932 1174 dbSNP
rs1419290007 1175 dbSNP
rs975098858 1176 dbSNP
rs1044131936 1177 dbSNP
rs930955168 1178 dbSNP
rs906941931 1180 dbSNP
rs908483777 1183 dbSNP
rs1003490789 1190 dbSNP
rs1170099911 1191 dbSNP
rs1031818674 1192 dbSNP
rs878878659 1199 dbSNP
rs1222798243 1203 dbSNP
rs1352588385 1205 dbSNP
rs1258547933 1217 dbSNP
rs1240643229 1224 dbSNP
rs1316969021 1228 dbSNP
rs1398140859 1229 dbSNP
rs1403563200 1230 dbSNP
rs1347820676 1231 dbSNP
rs1304084110 1232 dbSNP
rs568669648 1237 dbSNP
rs1399763033 1242 dbSNP
rs371948167 1243 dbSNP
rs1383128810 1247 dbSNP
rs1290853620 1251 dbSNP
rs1454426744 1268 dbSNP
rs956515770 1269 dbSNP
rs1330225456 1271 dbSNP
rs906327898 1273 dbSNP
rs7199631 1282 dbSNP
rs771436233 1283 dbSNP
rs774957177 1284 dbSNP
rs954032106 1286 dbSNP
rs985426119 1294 dbSNP
rs894547055 1295 dbSNP
rs1259299541 1298 dbSNP
rs557678566 1299 dbSNP
rs1485909386 1303 dbSNP
rs1254859833 1306 dbSNP
rs543088375 1307 dbSNP
rs965489754 1308 dbSNP
rs1284452805 1309 dbSNP
rs368002149 1314 dbSNP
rs976345466 1317 dbSNP
rs1298016675 1319 dbSNP
rs1334851450 1322 dbSNP
rs919084314 1322 dbSNP
rs1408293126 1325 dbSNP
rs999473031 1325 dbSNP
rs1177050087 1326 dbSNP
rs1019787330 1327 dbSNP
rs965898362 1329 dbSNP
rs1336799130 1331 dbSNP
rs575971387 1337 dbSNP
rs929108119 1338 dbSNP
rs1428698502 1341 dbSNP
rs150771166 1345 dbSNP
rs139169172 1348 dbSNP
rs562369049 1349 dbSNP
rs572986523 1350 dbSNP
rs540361559 1351 dbSNP
rs561606198 1353 dbSNP
rs571394494 1353 dbSNP
rs371826262 1360 dbSNP
rs906969205 1361 dbSNP
rs1316230226 1363 dbSNP
rs1193144116 1367 dbSNP
rs1371553926 1373 dbSNP
rs938429355 1375 dbSNP
rs1053249504 1376 dbSNP
rs952449817 1377 dbSNP
rs780362692 1378 dbSNP
rs1409257271 1380 dbSNP
rs1394091541 1383 dbSNP
rs983792533 1384 dbSNP
rs532044086 1386 dbSNP
rs1402171949 1388 dbSNP
rs1011715377 1392 dbSNP
rs939963325 1393 dbSNP
rs111407364 1394 dbSNP
rs927837187 1398 dbSNP
rs747421721 1403 dbSNP
rs761646040 1408 dbSNP
rs562809733 1421 dbSNP
rs767372028 1422 dbSNP
rs533030667 1426 dbSNP
rs1006936459 1430 dbSNP
rs1248357177 1437 dbSNP
rs1297268857 1455 dbSNP
rs114422383 1457 dbSNP
rs773145426 1458 dbSNP
rs551962315 1460 dbSNP
rs916033134 1469 dbSNP
rs1391817663 1471 dbSNP
rs1364668523 1473 dbSNP
rs1270237489 1474 dbSNP
rs947449625 1479 dbSNP
rs71400135 1480 dbSNP
rs116475344 1482 dbSNP
rs1468152274 1483 dbSNP
rs1235155762 1494 dbSNP
rs368922513 1502 dbSNP
rs1282214640 1505 dbSNP
rs984579610 1508 dbSNP
rs1267158938 1513 dbSNP
rs75597714 1520 dbSNP
rs948619625 1524 dbSNP
rs1041667159 1547 dbSNP
rs980201806 1555 dbSNP
rs1352921962 1558 dbSNP
rs1281229577 1560 dbSNP
rs928331867 1564 dbSNP
rs765216102 1565 dbSNP
rs1344673073 1569 dbSNP
rs534826063 1576 dbSNP
rs761732076 1577 dbSNP
rs891506758 1580 dbSNP
rs115350560 1581 dbSNP
rs75100204 1582 dbSNP
rs1453135809 1589 dbSNP
rs1159683573 1594 dbSNP
rs1480366017 1597 dbSNP
rs1202099500 1606 dbSNP
rs1490615527 1609 dbSNP
rs1241805883 1614 dbSNP
rs1005227398 1617 dbSNP
rs890066993 1623 dbSNP
rs569591723 1632 dbSNP
rs1284999123 1633 dbSNP
rs1396202436 1637 dbSNP
rs1322799198 1638 dbSNP
rs1281293726 1649 dbSNP
rs534832745 1658 dbSNP
rs1225177695 1659 dbSNP
rs1020257873 1665 dbSNP
rs1367970154 1669 dbSNP
rs901176547 1670 dbSNP
rs961313191 1675 dbSNP
rs1346476059 1679 dbSNP
rs1419537388 1686 dbSNP
rs778368246 1694 dbSNP
rs1382372514 1696 dbSNP
rs927900080 1698 dbSNP
rs1318431391 1699 dbSNP
rs959269683 1699 dbSNP
rs183024143 1704 dbSNP
rs1480977394 1707 dbSNP
rs113830911 1708 dbSNP
rs558471794 1712 dbSNP
rs952795355 1718 dbSNP
rs1419176397 1721 dbSNP
rs984610779 1728 dbSNP
rs947459393 1729 dbSNP
rs1348477962 1731 dbSNP
rs1016036975 1739 dbSNP
rs969833487 1746 dbSNP
rs1239210500 1747 dbSNP
rs1183109251 1749 dbSNP
rs1258698848 1754 dbSNP
rs1460026607 1754 dbSNP
rs372649385 1755 dbSNP
rs1271960236 1756 dbSNP
rs1205884195 1759 dbSNP
rs1363682126 1759 dbSNP
rs1297877443 1760 dbSNP
rs1451360314 1762 dbSNP
rs924650999 1763 dbSNP
rs1339277483 1764 dbSNP
rs980059691 1765 dbSNP
rs928505946 1768 dbSNP
rs934681227 1777 dbSNP
rs566502059 1779 dbSNP
rs77325073 1780 dbSNP
rs1420563016 1789 dbSNP
rs988876638 1792 dbSNP
rs913026467 1795 dbSNP
rs1195562260 1803 dbSNP
rs555478772 1805 dbSNP
rs1254228769 1811 dbSNP
rs1439586893 1817 dbSNP
rs187560137 1819 dbSNP
rs1365857803 1820 dbSNP
rs544419618 1821 dbSNP
rs13333603 1823 dbSNP
rs942822693 1826 dbSNP
rs1202261921 1827 dbSNP
rs1041308118 1828 dbSNP
rs12931867 1831 dbSNP
rs12932907 1832 dbSNP
rs1309028899 1836 dbSNP
rs888586840 1837 dbSNP
rs1005319772 1838 dbSNP
rs1327294598 1840 dbSNP
rs577400691 1841 dbSNP
rs1396085370 1844 dbSNP
rs748874233 1844 dbSNP
rs994218229 1848 dbSNP
rs865906169 1850 dbSNP
rs544930819 1851 dbSNP
rs12932924 1853 dbSNP
rs961143721 1856 dbSNP
rs1003656230 1859 dbSNP
rs143186729 1861 dbSNP
rs1371485230 1864 dbSNP
rs528510242 1865 dbSNP
rs1422917984 1871 dbSNP
rs1034690676 1880 dbSNP
rs1390702918 1882 dbSNP
rs1407245528 1883 dbSNP
rs1175353973 1891 dbSNP
rs540223645 1896 dbSNP
rs1221310800 1897 dbSNP
rs1489748617 1899 dbSNP
rs1293454796 1901 dbSNP
rs1337243912 1906 dbSNP
rs1023650404 1908 dbSNP
rs1305497223 1913 dbSNP
rs1225936313 1914 dbSNP
rs969869574 1925 dbSNP
rs146864999 1930 dbSNP
rs1403454963 1932 dbSNP
rs915089247 1938 dbSNP
rs1294323233 1953 dbSNP
rs1035647994 1954 dbSNP
rs1332922821 1955 dbSNP
rs1362069754 1956 dbSNP
rs960228846 1958 dbSNP
rs967848108 1963 dbSNP
rs977932739 1968 dbSNP
rs1269481094 1970 dbSNP
rs8058979 1971 dbSNP
rs912890578 1972 dbSNP
rs1270672839 1975 dbSNP
rs968344863 1976 dbSNP
rs1209992821 1985 dbSNP
rs934753946 1986 dbSNP
rs978526151 1991 dbSNP
rs910940188 1992 dbSNP
rs977195976 1994 dbSNP
rs922572796 1996 dbSNP
rs1175931922 1998 dbSNP
rs149007234 1999 dbSNP
rs1041606374 2000 dbSNP
rs1420123211 2003 dbSNP
rs1187255186 2007 dbSNP
rs1290761579 2011 dbSNP
rs1416769983 2021 dbSNP
rs35633157 2022 dbSNP
rs771588177 2022 dbSNP
rs930205240 2023 dbSNP
rs1394505374 2024 dbSNP
rs941557156 2026 dbSNP
rs1259187806 2031 dbSNP
rs1047272943 2039 dbSNP
rs569503925 2041 dbSNP
rs1005468029 2043 dbSNP
rs1464944545 2046 dbSNP
rs1296452230 2052 dbSNP
rs879646524 2053 dbSNP
rs1003256598 2054 dbSNP
rs1326143776 2056 dbSNP
rs773090270 2057 dbSNP
rs1227131006 2058 dbSNP
rs905281418 2068 dbSNP
rs1001416173 2071 dbSNP
rs1382053734 2072 dbSNP
rs1336035092 2073 dbSNP
rs1468121411 2082 dbSNP
rs1353829903 2088 dbSNP
rs1235312515 2089 dbSNP
rs1172984244 2090 dbSNP
rs1461287520 2096 dbSNP
rs894782485 2097 dbSNP
rs1170030463 2098 dbSNP
rs1012187743 2110 dbSNP
rs1241946267 2113 dbSNP
rs1022242074 2114 dbSNP
rs760645398 2115 dbSNP
rs1257443406 2116 dbSNP
rs1337841823 2117 dbSNP
rs960013495 2118 dbSNP
rs533541193 2119 dbSNP
rs1202520022 2127 dbSNP
rs1010584495 2128 dbSNP
rs1253646348 2129 dbSNP
rs1020190699 2131 dbSNP
rs143842885 2132 dbSNP
rs1200273596 2133 dbSNP
rs567161491 2134 dbSNP
rs1018075858 2135 dbSNP
rs776545224 2137 dbSNP
rs538563734 2138 dbSNP
rs796572271 2143 dbSNP
rs1427473724 2148 dbSNP
rs922623621 2150 dbSNP
rs1161180171 2151 dbSNP
rs1473491163 2153 dbSNP
rs1369607829 2157 dbSNP
rs1181648055 2158 dbSNP
rs932678334 2161 dbSNP
rs1167669989 2180 dbSNP
rs1206284293 2181 dbSNP
rs985416104 2183 dbSNP
rs1289857903 2199 dbSNP
rs1357069510 2201 dbSNP
rs765434602 2208 dbSNP
rs1238195340 2209 dbSNP
rs910171682 2213 dbSNP
rs1309678589 2214 dbSNP
rs1462394727 2226 dbSNP
rs976975108 2227 dbSNP
rs752877748 2228 dbSNP
rs930133707 2229 dbSNP
rs982996019 2234 dbSNP
rs1373328627 2235 dbSNP
rs1416859451 2240 dbSNP
rs533791855 2244 dbSNP
rs897286010 2253 dbSNP
rs1158517453 2255 dbSNP
rs939109657 2262 dbSNP
rs555014639 2273 dbSNP
rs1183438475 2275 dbSNP
rs941401266 2282 dbSNP
rs1045043431 2285 dbSNP
rs1011947905 2291 dbSNP
rs905300874 2294 dbSNP
rs1297764666 2296 dbSNP
rs1223961950 2299 dbSNP
rs1452284399 2302 dbSNP
rs558303930 2306 dbSNP
rs763078757 2309 dbSNP
rs1234131542 2313 dbSNP
rs1056524762 2314 dbSNP
rs192635005 2323 dbSNP
rs537579153 2324 dbSNP
rs555817913 2325 dbSNP
rs1438120503 2331 dbSNP
rs904438453 2332 dbSNP
rs534545134 2333 dbSNP
rs965884089 2338 dbSNP
rs370350666 2340 dbSNP
rs963716152 2341 dbSNP
rs1407753344 2345 dbSNP
rs1427588075 2346 dbSNP
rs976924959 2347 dbSNP
rs1172862659 2348 dbSNP
rs1478509092 2355 dbSNP
rs1241716456 2359 dbSNP
rs1191210992 2363 dbSNP
rs1466297886 2366 dbSNP
rs954123770 2370 dbSNP
rs1393187352 2373 dbSNP
rs1029372136 2379 dbSNP
rs1174006771 2380 dbSNP
rs554636447 2381 dbSNP
rs963298248 2382 dbSNP
rs1269214807 2384 dbSNP
rs553661377 2388 dbSNP
rs982907571 2395 dbSNP
rs918768071 2409 dbSNP
rs1321839349 2413 dbSNP
rs1452483234 2414 dbSNP
rs867191355 2415 dbSNP
rs1178745993 2423 dbSNP
rs1415403524 2430 dbSNP
rs373648659 2435 dbSNP
rs574492367 2440 dbSNP
rs910176756 2441 dbSNP
rs939556909 2442 dbSNP
rs572201650 2445 dbSNP
rs1248682158 2446 dbSNP
rs1048194 2447 dbSNP
rs183167813 2451 dbSNP
rs947782056 2452 dbSNP
rs1350658194 2462 dbSNP
rs1271852088 2471 dbSNP
rs1235533237 2483 dbSNP
rs1343705200 2494 dbSNP
rs1283961544 2496 dbSNP
rs1043413613 2498 dbSNP
rs903490847 2500 dbSNP
rs999868842 2506 dbSNP
rs1052387970 2511 dbSNP
rs1449230964 2517 dbSNP
rs1354244680 2525 dbSNP
rs145084979 2525 dbSNP
rs901744805 2525 dbSNP
rs997341193 2531 dbSNP
rs1465010946 2536 dbSNP
rs1411552488 2544 dbSNP
rs980770043 2552 dbSNP
rs573959749 2555 dbSNP
rs1232042000 2556 dbSNP
rs556690207 2558 dbSNP
rs756445562 2559 dbSNP
rs148137235 2566 dbSNP
rs892518840 2568 dbSNP
rs945902022 2570 dbSNP
rs533607882 2572 dbSNP
rs1399176693 2576 dbSNP
rs904469172 2579 dbSNP
rs918872137 2580 dbSNP
rs576774482 2584 dbSNP
rs141061694 2585 dbSNP
rs899498842 2589 dbSNP
rs565605816 2598 dbSNP
rs1373874492 2614 dbSNP
rs187645366 2618 dbSNP
rs916710774 2620 dbSNP
rs1166856773 2621 dbSNP
rs947791843 2627 dbSNP
rs1411103262 2628 dbSNP
rs1179833278 2634 dbSNP
rs1473443458 2636 dbSNP
rs1252105886 2652 dbSNP
rs1029863070 2653 dbSNP
rs771536776 2660 dbSNP
rs777313214 2662 dbSNP
rs1043473572 2664 dbSNP
rs1316908854 2675 dbSNP
rs1004364427 2680 dbSNP
rs1230632505 2683 dbSNP
rs935041896 2685 dbSNP
rs527945702 2691 dbSNP
rs554278929 2693 dbSNP
rs901801621 2705 dbSNP
rs1225828907 2711 dbSNP
rs1285984045 2718 dbSNP
rs138237252 2719 dbSNP
rs1453143820 2719 dbSNP
rs962822925 2720 dbSNP
rs78866913 2724 dbSNP
rs926857292 2726 dbSNP
rs537845797 2728 dbSNP
rs549508021 2733 dbSNP
rs1197755710 2737 dbSNP
rs570972061 2742 dbSNP
rs1050229339 2744 dbSNP
rs770965853 2768 dbSNP
rs888921829 2769 dbSNP
rs192169326 2771 dbSNP
rs1330270035 2780 dbSNP
rs913996526 2790 dbSNP
rs577787931 2793 dbSNP
rs1409035045 2797 dbSNP
rs879505446 2803 dbSNP
rs12456 2804 dbSNP
rs1302231892 2806 dbSNP
rs994211763 2809 dbSNP
rs1363040435 2815 dbSNP
rs925792183 2821 dbSNP
rs1026062703 2822 dbSNP
rs935778830 2828 dbSNP
rs1040033427 2829 dbSNP
rs992376297 2831 dbSNP
rs1379015829 2832 dbSNP
rs899738773 2833 dbSNP
rs998301383 2835 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084066. RNA binding protein: AGO2. Condition:CLIP_noemetine_SantaCruzAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000305850.5 | 3UTR | AAAUGGAGGGAGGAAGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000305850.5 | 3UTR | AAAAUGGAGGGAGGAAGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084066
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SantaCruzAb
Location of target site ENST00000305850.5 | 3UTR | AAAAUGGAGGGAGGAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE38226 Liver fibrosis 0.618 1.4e-3 0.484 1.3e-2 21 Click to see details
GSE42095 Differentiated embryonic stem cells 0.581 1.8e-3 0.668 2.5e-4 23 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.41 2.1e-2 0.345 4.6e-2 25 Click to see details
GSE26953 Aortic valvular endothelial cells -0.309 7.1e-2 -0.392 2.9e-2 24 Click to see details
GSE28260 Renal cortex and medulla -0.358 1.1e-1 -0.407 8.4e-2 13 Click to see details
GSE32688 Pancreatic cancer 0.1 2.9e-1 -0.005 4.9e-1 32 Click to see details
GSE28544 Breast cancer 0.009 4.8e-1 0.004 4.9e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
186 hsa-miR-1303 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT035871 SOAT1 sterol O-acyltransferase 1 1 1
MIRT035872 FHOD3 formin homology 2 domain containing 3 1 1
MIRT035873 RPL7A ribosomal protein L7a 1 1
MIRT035874 NCAPD2 non-SMC condensin I complex subunit D2 1 1
MIRT035875 RPS8 ribosomal protein S8 1 1
MIRT035876 AHNAK AHNAK nucleoprotein 1 1
MIRT035877 ACTB actin beta 1 1
MIRT035878 DEF8 differentially expressed in FDCP 8 homolog 1 1
MIRT035879 MET MET proto-oncogene, receptor tyrosine kinase 1 1
MIRT035880 MED13 mediator complex subunit 13 1 1
MIRT035881 FAT3 FAT atypical cadherin 3 1 1
MIRT035882 HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 1 1
MIRT035883 RPS16 ribosomal protein S16 1 1
MIRT035884 CDK6 cyclin dependent kinase 6 1 1
MIRT035885 GEMIN5 gem nuclear organelle associated protein 5 1 1
MIRT035886 PITRM1 pitrilysin metallopeptidase 1 1 1
MIRT035887 PRRC2A proline rich coiled-coil 2A 1 1
MIRT035888 KIAA0226 RUN and cysteine rich domain containing beclin 1 interacting protein 1 1
MIRT035889 MLLT6 MLLT6, PHD finger containing 1 1
MIRT035890 EIF3I eukaryotic translation initiation factor 3 subunit I 1 1
MIRT035891 FASN fatty acid synthase 1 1
MIRT035892 LEPREL4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 1 1
MIRT035893 HSCB HscB mitochondrial iron-sulfur cluster cochaperone 1 1
MIRT035894 PSME4 proteasome activator subunit 4 1 1
MIRT035895 FRS2 fibroblast growth factor receptor substrate 2 1 1
MIRT035896 ZNF264 zinc finger protein 264 1 1
MIRT035897 HYLS1 HYLS1, centriolar and ciliogenesis associated 1 1
MIRT035898 USP54 ubiquitin specific peptidase 54 1 1
MIRT035899 L1TD1 LINE1 type transposase domain containing 1 1 1
MIRT035900 OR51E2 olfactory receptor family 51 subfamily E member 2 1 1
MIRT053762 CLDN18 claudin 18 3 1
MIRT060730 RPS3 ribosomal protein S3 2 2
MIRT083986 RAB22A RAB22A, member RAS oncogene family 2 2
MIRT098550 TBPL1 TATA-box binding protein like 1 2 6
MIRT134983 TWF1 twinfilin actin binding protein 1 2 4
MIRT136956 FNDC3A fibronectin type III domain containing 3A 2 2
MIRT222065 PURB purine rich element binding protein B 2 2
MIRT239574 UBN2 ubinuclein 2 2 4
MIRT261820 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT264698 C11ORF57 chromosome 11 open reading frame 57 2 4
MIRT308476 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT377481 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT442304 NEU3 neuraminidase 3 2 2
MIRT446083 SLC30A10 solute carrier family 30 member 10 2 2
MIRT449606 PRPF4 pre-mRNA processing factor 4 2 2
MIRT453767 NUCB1 nucleobindin 1 2 10
MIRT455603 SRSF3 serine and arginine rich splicing factor 3 2 2
MIRT455913 KIF2C kinesin family member 2C 2 2
MIRT460091 ZYG11B zyg-11 family member B, cell cycle regulator 2 4
MIRT460866 UBE2S ubiquitin conjugating enzyme E2 S 2 2
MIRT461339 NUP133 nucleoporin 133 2 2
MIRT463769 YOD1 YOD1 deubiquitinase 2 2
MIRT466368 THAP1 THAP domain containing 1 2 4
MIRT467168 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT468703 SDHD succinate dehydrogenase complex subunit D 2 2
MIRT469122 RNF126 ring finger protein 126 2 2
MIRT472426 NCBP2 nuclear cap binding protein subunit 2 2 4
MIRT479420 CDKN1B cyclin dependent kinase inhibitor 1B 2 8
MIRT484260 FAM177A1 family with sequence similarity 177 member A1 2 2
MIRT485468 IL6ST interleukin 6 signal transducer 2 10
MIRT490237 H2AFZ H2A histone family member Z 2 6
MIRT491002 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT492127 SUMO2 small ubiquitin-like modifier 2 2 2
MIRT499169 RBPJL recombination signal binding protein for immunoglobulin kappa J region like 2 2
MIRT499825 PCSK9 proprotein convertase subtilisin/kexin type 9 2 8
MIRT501794 NRAS NRAS proto-oncogene, GTPase 2 2
MIRT503441 GINS4 GINS complex subunit 4 2 4
MIRT503688 MAVS mitochondrial antiviral signaling protein 2 5
MIRT506926 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT511430 HOXA10 homeobox A10 2 6
MIRT512415 LAYN layilin 2 4
MIRT513791 NIPAL3 NIPA like domain containing 3 2 4
MIRT516163 NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 2 4
MIRT516513 PARK2 parkin RBR E3 ubiquitin protein ligase 2 2
MIRT516915 HINFP histone H4 transcription factor 2 2
MIRT517102 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT517350 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT518019 ABHD15 abhydrolase domain containing 15 2 2
MIRT520945 SRSF10 serine and arginine rich splicing factor 10 2 2
MIRT525250 RNF213 ring finger protein 213 2 2
MIRT530634 PPIC peptidylprolyl isomerase C 2 4
MIRT530671 CHRNB1 cholinergic receptor nicotinic beta 1 subunit 2 4
MIRT531563 ILDR1 immunoglobulin like domain containing receptor 1 2 2
MIRT538205 CYR61 cysteine rich angiogenic inducer 61 2 2
MIRT538419 COLEC10 collectin subfamily member 10 2 2
MIRT541964 ZNF485 zinc finger protein 485 2 2
MIRT543088 KNSTRN kinetochore localized astrin/SPAG5 binding protein 2 2
MIRT543257 ZNF662 zinc finger protein 662 2 2
MIRT543589 KIAA1549 KIAA1549 2 2
MIRT543955 RNF20 ring finger protein 20 2 2
MIRT544043 C9orf64 chromosome 9 open reading frame 64 2 4
MIRT548064 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT548240 FBXW7 F-box and WD repeat domain containing 7 2 2
MIRT548442 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 2
MIRT548623 DAZAP1 DAZ associated protein 1 2 4
MIRT548770 COLEC12 collectin subfamily member 12 2 2
MIRT549506 HDDC2 HD domain containing 2 2 4
MIRT551924 AKAP8 A-kinase anchoring protein 8 2 4
MIRT555656 PGRMC1 progesterone receptor membrane component 1 2 2
MIRT556286 MAP3K5 mitogen-activated protein kinase kinase kinase 5 2 2
MIRT557012 HOXD13 homeobox D13 2 4
MIRT563907 CLSPN claspin 2 2
MIRT565527 SON SON DNA binding protein 2 2
MIRT568000 COMMD2 COMM domain containing 2 2 2
MIRT569831 PLA2G16 phospholipase A2 group XVI 2 4
MIRT573905 PARP1 poly(ADP-ribose) polymerase 1 2 2
MIRT616589 KLHL9 kelch like family member 9 2 2
MIRT617137 ZNF556 zinc finger protein 556 2 2
MIRT617400 API5 apoptosis inhibitor 5 2 2
MIRT617455 CCS copper chaperone for superoxide dismutase 2 2
MIRT617799 ZNF793 zinc finger protein 793 2 2
MIRT618190 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT618303 GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 2 2
MIRT618329 ZNF813 zinc finger protein 813 2 2
MIRT618820 PHF20 PHD finger protein 20 2 2
MIRT619153 PPDPF pancreatic progenitor cell differentiation and proliferation factor 2 2
MIRT619530 ZNF708 zinc finger protein 708 2 2
MIRT619849 KIR3DX1 killer cell immunoglobulin like receptor, three Ig domains X1 2 2
MIRT620806 SLC26A2 solute carrier family 26 member 2 2 2
MIRT621312 YIPF4 Yip1 domain family member 4 2 2
MIRT621358 GUCA1B guanylate cyclase activator 1B 2 2
MIRT621366 ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2 2
MIRT621547 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT621883 TAOK1 TAO kinase 1 2 2
MIRT622451 RNF19B ring finger protein 19B 2 2
MIRT623404 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT623587 IPO9 importin 9 2 2
MIRT623974 FAM63A MINDY lysine 48 deubiquitinase 1 2 2
MIRT624086 DPP8 dipeptidyl peptidase 8 2 2
MIRT624108 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT632486 RNF8 ring finger protein 8 2 2
MIRT634057 PLIN3 perilipin 3 2 2
MIRT634657 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT640682 MCUR1 mitochondrial calcium uniporter regulator 1 2 2
MIRT641242 CENPN centromere protein N 2 2
MIRT642260 ZNF677 zinc finger protein 677 2 2
MIRT642954 RELA RELA proto-oncogene, NF-kB subunit 2 2
MIRT644326 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT644632 ICA1L islet cell autoantigen 1 like 2 2
MIRT645721 POLR3A RNA polymerase III subunit A 2 2
MIRT647850 LYPLA1 lysophospholipase I 2 2
MIRT649281 NEK8 NIMA related kinase 8 2 2
MIRT650038 VHL von Hippel-Lindau tumor suppressor 2 2
MIRT650354 RRP36 ribosomal RNA processing 36 2 2
MIRT651144 ZNF384 zinc finger protein 384 2 2
MIRT651778 UTP6 UTP6, small subunit processome component 2 2
MIRT652576 TLCD2 TLC domain containing 2 2 2
MIRT654621 PTPRJ protein tyrosine phosphatase, receptor type J 2 2
MIRT656023 MYO5A myosin VA 2 2
MIRT656105 MSRB3 methionine sulfoxide reductase B3 2 2
MIRT657749 GMEB1 glucocorticoid modulatory element binding protein 1 2 2
MIRT657924 GATSL2 cytosolic arginine sensor for mTORC1 subunit 2 2 2
MIRT658848 DUSP19 dual specificity phosphatase 19 2 2
MIRT659100 DENND6A DENN domain containing 6A 2 2
MIRT659153 DCX doublecortin 2 2
MIRT660870 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT661941 FAHD1 fumarylacetoacetate hydrolase domain containing 1 2 2
MIRT663577 C10orf32 BLOC-1 related complex subunit 7 2 2
MIRT664625 WDPCP WD repeat containing planar cell polarity effector 2 4
MIRT666562 RHOBTB3 Rho related BTB domain containing 3 2 2
MIRT669992 GPR156 G protein-coupled receptor 156 2 4
MIRT670445 RSBN1L round spermatid basic protein 1 like 2 2
MIRT670853 IFNAR1 interferon alpha and beta receptor subunit 1 2 4
MIRT671942 SPPL3 signal peptide peptidase like 3 2 2
MIRT674269 LMOD3 leiomodin 3 2 2
MIRT674424 MIOX myo-inositol oxygenase 2 4
MIRT674982 ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C1 (subunit 9) 2 2
MIRT675038 BACE2 beta-site APP-cleaving enzyme 2 2 4
MIRT675309 C2orf68 chromosome 2 open reading frame 68 2 2
MIRT675641 TTPAL alpha tocopherol transfer protein like 2 2
MIRT688688 CPS1 carbamoyl-phosphate synthase 1 2 2
MIRT689369 ZNF101 zinc finger protein 101 2 2
MIRT689605 AKAP6 A-kinase anchoring protein 6 2 2
MIRT691715 LARS leucyl-tRNA synthetase 2 2
MIRT695473 TRAT1 T-cell receptor associated transmembrane adaptor 1 2 2
MIRT695530 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 2
MIRT695878 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT696586 ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2 2
MIRT703007 HEATR5A HEAT repeat containing 5A 2 2
MIRT707942 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 2
MIRT709765 GPR183 G protein-coupled receptor 183 2 2
MIRT710332 ZNF669 zinc finger protein 669 2 2
MIRT713249 ZFP30 ZFP30 zinc finger protein 2 2
MIRT716613 RBM18 RNA binding motif protein 18 2 2
MIRT733414 BAG2 BCL2 associated athanogene 2 2 0
MIRT756135 THSD7A thrombospondin type 1 domain containing 7A 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-1 Anthocyanin NULL 145858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Caffeic acid NULL 689043 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Catechin approved 9064 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Ferulic acid NULL 445858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Hesperidin NULL 10621 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Quercetin NULL 5280343 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 up-regulated
miR-1 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Quantitative real-time PCR myocardial differentiation of mouse ES cells 19521018 2009 down-regulated
miR-1 Sulfonyl-hydrazone-1 (SHZ) NULL NULL Quantitative real-time PCR Murine broblast-derived Induced pluripotent stem cells 21445862 2011 up-regulated
miR-1 Cocaine NULL 446220 Next-generation sequencing ventral striatum 21708909 2011 up-regulated
miR-1 Atorvastatin approved 60823 Quantitative real-time PCR Cardiomyocyte 23860036 2013 down-regualted
miR-1 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-1 Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 Palmitic acid approved 985 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miR-1 Essential amino acids (EAA) NULL NULL Quantitative real-time PCR skeletal muscle of young adults 19828686 2009 up-regulated
miR-1 Hydrogen peroxide (H2O2) NULL 784 Quantitative real-time PCR Human umbilical vein endothelial cells 21527937 2011 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Microarray apoptosis-resistant breast cancer cells 21971930 2011 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-1 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-1 Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR cardia 22889704 2012 up-regulated
miR-1 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-1 Quinidine approved 441074 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 up-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 down-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR post-infarction rat cardiomyocytes 21220930 2011 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miR-1 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-1303 Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (RKO)
hsa-miR-1303 Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-miR-1303 Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-1303 Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-1303 Rituximab sensitive High Diffuse Large B-Cell Lymphoma cell line (DB, NU-DHL-1, NU-DUL-1, MC-116, SU-DHL-4, SU-DHL-5, FARAGE, HBL-1, OCI-Ly3, OCI-Ly7, OCI-Ly8, OCI-Ly19, RIVA, SU-DHL-8, U2932)
hsa-miR-1303 Etoposide 36462 NSC141540 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-miR-1303 Doxorubicin 31703 NSC123127 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-miR-1303 Vinorelbine 44424639 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-miR-1303 Vincristine 5978 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-miR-1303 Paclitaxel 36314 NSC125973 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-mir-1303 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-1303 Cisplatin 5460033 NSC119875 approved resistant cell line (W1)
hsa-mir-1303 Topotecan 60699 NSC609699 approved resistant cell line (W1)
hsa-mir-1303 Androstenedione+Letrozole resistant cell line (MCF-7)
hsa-miR-1303 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-1303 Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-1303 Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-1303 Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-1303 Palbociclib 5330286 NSC758247 approved resistant tissue (breast cancer)
hsa-miR-1303 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-1303 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-1303 Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-1303 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-1303 Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-1303 Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)
hsa-miR-1303 Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-1303 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

Error report submission