miRTarBase - #MIRT642735


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pre-miRNA Information
pre-miRNA hsa-mir-6867   
Genomic Coordinates chr17: 40193597 - 40193663
Description Homo sapiens miR-6867 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6867-3p
Sequence 47| CUCUCCCUCUUUACCCACUAG |67
Evidence Experimental
Experiments Meta-analysis
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM7811173 21 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1403216522 1 dbSNP
rs781776276 3 dbSNP
rs202050374 4 dbSNP
rs367842831 5 dbSNP
rs1223489976 6 dbSNP
rs907256096 9 dbSNP
rs753257137 14 dbSNP
rs757843554 17 dbSNP
rs371369162 18 dbSNP
Putative Targets

Gene Information
Gene Symbol TDRD6   
Synonyms CT41.2, NY-CO-45, SPATA36, TDR2, bA446F17.4
Description tudor domain containing 6
Transcript NM_001010870   
Other Transcripts NM_001168359   
Expression
Putative miRNA Targets on TDRD6
3'UTR of TDRD6
(miRNA target sites are highlighted)		 
>TDRD6|NM_001010870|3'UTR
   1 CCGTGGATCTATAGCTGTGGCCAATCAGTCAGAAGCTGCCCTTGAACAAGTGGCATCTTACGCAGACCAACAGAGTATTT
  81 GAGAAAATTGAAAACATGTAACCACAAGAAGTTGTCATTTTCAAAAACTTCTATATAGGTGGAAAACAAATTAGGTCTCA
 161 GGTTGATGGTGGGGTGTGTTTATAGTGATCCTGTTATATATACAGATCTGGGATCTTTCGTCTTTATTGTCTTACGTTTC
 241 TAATTAGTTGGGAGGATTTATTTTGCTAAACAGTTTACTAACACATTACATTTCAAAAACTATTTTGGTACCTTTCAAAT
 321 ACAGTGTTTAAATTAAAATAGAAAAATAAGGGCTCATGACAAGTACATTATTTGATTCTACTTAGGATAGCTTTTTAGCA
 401 GGATCTCCTTCAGAATTTTTGTCTTGACTTTGAATCTTTGCCTGTTTGTCTAAACATTTGACTAACATTCTGTTTGAATT
 481 TGGAAGTATTCTAATACAAGATTTGAATAAAGTTTATCCTTAAATAAAGTTTATCCTTAATATGATGGTCTCATTTTATT
 561 AAAAAGGAAATAGAACTCTTAAATATACTTGGTTCCATCTCTCCTCTGTAATGGAGGATTGGGGAAAGCATAGTAATATT
 641 AAATGTTAGCTCTTATGTATTAGTCACTTAGCTTATACTTTAAATGCATTTTTTCACTTTATTCATCAACTTTGAAGTGC
 721 ATATCAATATTATCCATATTTTATAGGTGAGAAAATTGAAGCTTCATAAAGAGGTTAAATAACTTGCCTAAGGTCAGATA
 801 GCTGATGAGTCTCAGAGGCTTGATCAAACCCAGACCTACCTAACTTTGAAGCCCATGACTTTTTAAACATGATTTTGCAA
 881 AGCATAGATCTTAGCTTTTAGAAACAGATCTGAGCTATATGCTGCTTAACAGATATGTGACATGGGCAAATTATGTAATA
 961 TTTTGAACTTTGATCTTCATCTGTAAAGTGGTGATAATAAAACCTTTCTTGCAGTGTTTTTTTAAGATGAGAAATAATTG
1041 ATATAAAGTCCCTGAAAAGGAGTAGGCATTTGATAAATGTGTCTTTCTTTACCCTGAAAAATACTCAGTGTGCACTATGT
1121 TAGGTTATTTCTTTTTAACCTTAACTTATTAGATATTTTCAATAGTTATTTTCTCCTTTCAGCATCAGCATGCGCCACCA
1201 ACAAAAGACTGTAAAAAACAAACAAACAAAAAAGTGTTGAATGGGACATCCATACAGTTGGAATGCTTATTTCTAAAATG
1281 AATAGGGAAAAGGTTTGCTAAATGAGACTGGGGTAAAGGTGTATCTCTGTGAAGCATTATCAGACTCTGAAGCCTAATGG
1361 AAATAGAATTATGAACCTTAAAAACCCATTATAATTTCCGTAAGTAGAAGGGAGAGAGGTTTGCATTAAAAGTAATTGAG
1441 GTAGATGAGTATATTACTTATTCCTGGAATAATGAATAGACAAGTTTGGCTTACTCATATAGATAATATAATGTGAATTG
1521 CCAGAAGCAAAGCTCAGAGAAGATGCATTAGGATCAGATTATAGGAAGCCTTCAATTTCAAGCTGAGTTTAACTCCCTAT
1601 TTTAAAAAATTTAATCTGAATGGCTACAGAAGTAAAATTTCTCAGAATGAGTGACTTTGCACCTGACACCACTAAGATAG
1681 GACTAGGGTACCAAATGAGTGGTATAAATTTTTATGTCCCCTGGGAAATAAAATCATTTTCCATGATTCCCATATTTATA
1761 AGTATAAATTCTTAAGCTATATTTTTACCTCCATTTAATCGTGTTATTCTGTTTTACTACTACATATAGAATTGAAAACA
1841 TTAAATAAAATTAACTGGAATATGAAGAAGCTAAATGTAATTCTGAATGTTTTATTATCCTTCACAGCCTTTGTGTGAGT
1921 AACTAATGTATTCTAACTGGAATCCCTGCTATATGCTGTAATACCTGTGGAACCTTTCTTTAGCAAGTAGAATGCCTTAA
2001 AGAATTAAAGAAAGTGTCAAAAAATTACCAATTTAATCCACTGCCTTTGCCTCATCTCTAATATTCTTAACCCTTCTCTA
2081 CTCCTTTTAGTCATCATTTGAAATTGTGTAGTACCACCAATCCTGTGCTGAAACAATGGCTTTTGCTTGTTCTAATTTTT
2161 CTTACCGTGACCAAAAGTCAAAGAGAAGAGCTGCCAAATTCTACCTAGAATATCATGTTGCTATAATTAAACTCCACTGC
2241 CCATAGTAGATAATAAAAGGCAAGAAATTGTTTTTTACTCTATGTTTAGGGAGTCTTGTATCATTGCAACAGGTTTTCAC
2321 TGGGATTTTGCCTGTTTTAATCTACTTGTCTGTCAAAGTAATGTAAAAACAGTTTTTAACTTCGACACTGAAAAGGAATC
2401 ATCTTTAAAATTAAAATTTAGGCTGATATGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gauCACCCAUUUCUCCCUCUc 5'
             ||  |||:| ||||||| 
Target 5' tccGTAAGTAGA-AGGGAGAg 3'
 1397 - 1416 157.00 -17.30
2 
miRNA  3' gaucaccCAUU-UCUCCCUCUc 5'
                 ||||  |||| ||| 
Target 5' attaaaaGTAATTGAGGTAGAt 3'
 1425 - 1446 122.00 -8.30
3 
miRNA  3' gaucacccAUUUCUCCCUCUc 5'
                  |:|| ||||| | 
Target 5' ttctaaaaTGAATAGGGAAAa 3'
 1271 - 1291 121.00 -6.22
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30105155 2 COSMIC
COSN26998201 4 COSMIC
COSM7964518 6 COSMIC
COSN26726532 31 COSMIC
COSN30503040 40 COSMIC
COSN30168922 45 COSMIC
COSN26998203 62 COSMIC
COSN30525686 66 COSMIC
COSN30465261 74 COSMIC
COSN26998202 90 COSMIC
COSN30100664 117 COSMIC
COSN15264395 137 COSMIC
COSN31605181 158 COSMIC
COSN31574326 220 COSMIC
COSN31586139 236 COSMIC
COSN31554560 237 COSMIC
COSN28834501 313 COSMIC
COSN23817841 359 COSMIC
COSN28834309 679 COSMIC
COSN23053711 819 COSMIC
COSN27736056 1220 COSMIC
COSN27921937 1228 COSMIC
COSN17037492 1279 COSMIC
COSN9784672 1388 COSMIC
COSN15149339 1400 COSMIC
COSN31959994 1533 COSMIC
COSN2163610 1628 COSMIC
COSN25298489 1700 COSMIC
COSN23776608 1801 COSMIC
COSN29106420 1895 COSMIC
COSN19290640 2217 COSMIC
COSN21006138 2417 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs769886840 1 dbSNP
rs778116005 3 dbSNP
rs749611205 4 dbSNP
rs1421771332 6 dbSNP
rs774670939 12 dbSNP
rs1241981338 16 dbSNP
rs1193735826 17 dbSNP
rs1368942670 18 dbSNP
rs1379106712 19 dbSNP
rs760216199 22 dbSNP
rs746404292 23 dbSNP
rs772605054 24 dbSNP
rs776094852 25 dbSNP
rs1266508574 27 dbSNP
rs1429999425 27 dbSNP
rs1299461138 40 dbSNP
rs1376540790 41 dbSNP
rs1435607929 42 dbSNP
rs750486925 47 dbSNP
rs764788432 49 dbSNP
rs1384150049 53 dbSNP
rs921093935 61 dbSNP
rs772926474 62 dbSNP
rs762601997 63 dbSNP
rs192738120 87 dbSNP
rs1167037260 92 dbSNP
rs1427205119 98 dbSNP
rs149494397 101 dbSNP
rs1189574645 103 dbSNP
rs1466583678 108 dbSNP
rs1249494645 112 dbSNP
rs1207642572 128 dbSNP
rs1487958749 137 dbSNP
rs1019421551 138 dbSNP
rs372993703 139 dbSNP
rs377160627 140 dbSNP
rs1296837065 153 dbSNP
rs1477237035 155 dbSNP
rs1043366527 161 dbSNP
rs1367020815 168 dbSNP
rs1032046342 171 dbSNP
rs1391747146 174 dbSNP
rs957690126 174 dbSNP
rs990593562 175 dbSNP
rs1427947693 180 dbSNP
rs1390100600 182 dbSNP
rs533930348 191 dbSNP
rs903520604 194 dbSNP
rs916304369 197 dbSNP
rs147188374 198 dbSNP
rs1450637173 201 dbSNP
rs1033424498 210 dbSNP
rs896646448 220 dbSNP
rs748090308 221 dbSNP
rs1273302714 223 dbSNP
rs1166744425 232 dbSNP
rs1409492783 232 dbSNP
rs1272806864 235 dbSNP
rs1370217776 237 dbSNP
rs1410708791 243 dbSNP
rs1303758759 244 dbSNP
rs570415023 250 dbSNP
rs138855105 253 dbSNP
rs60795357 255 dbSNP
rs796269283 269 dbSNP
rs534439855 273 dbSNP
rs1308721031 281 dbSNP
rs1037235543 285 dbSNP
rs985454818 286 dbSNP
rs555863832 289 dbSNP
rs1172338596 290 dbSNP
rs965110532 291 dbSNP
rs1275372382 297 dbSNP
rs758480599 300 dbSNP
rs1377840988 303 dbSNP
rs931293650 311 dbSNP
rs12528857 313 dbSNP
rs1250371409 328 dbSNP
rs746532214 332 dbSNP
rs1356851477 340 dbSNP
rs770641190 352 dbSNP
rs1342229048 356 dbSNP
rs933411208 364 dbSNP
rs1199654224 368 dbSNP
rs986604156 370 dbSNP
rs913733331 372 dbSNP
rs902340654 375 dbSNP
rs1350137498 383 dbSNP
rs1450245682 401 dbSNP
rs1289014667 403 dbSNP
rs1198534537 405 dbSNP
rs1339195316 416 dbSNP
rs945276675 422 dbSNP
rs1415559833 448 dbSNP
rs999482056 454 dbSNP
rs1157439283 463 dbSNP
rs1044076438 467 dbSNP
rs1032243650 475 dbSNP
rs1410826989 481 dbSNP
rs184008275 498 dbSNP
rs1389681415 504 dbSNP
rs1344044309 506 dbSNP
rs1442942617 506 dbSNP
rs903512316 506 dbSNP
rs1328728016 513 dbSNP
rs937709678 519 dbSNP
rs1269055041 524 dbSNP
rs990497167 525 dbSNP
rs1354406677 530 dbSNP
rs1283679583 534 dbSNP
rs1449346555 543 dbSNP
rs1430468213 549 dbSNP
rs1342803067 557 dbSNP
rs776379249 558 dbSNP
rs896215082 562 dbSNP
rs1387445418 573 dbSNP
rs970886276 585 dbSNP
rs1402095930 586 dbSNP
rs1410906705 595 dbSNP
rs981849627 596 dbSNP
rs1323909944 606 dbSNP
rs928827738 607 dbSNP
rs749568079 612 dbSNP
rs189084970 618 dbSNP
rs1026446778 632 dbSNP
rs553989959 633 dbSNP
rs142861338 643 dbSNP
rs1296768127 644 dbSNP
rs769041285 651 dbSNP
rs886608735 653 dbSNP
rs1218130812 664 dbSNP
rs972980966 666 dbSNP
rs1289178878 674 dbSNP
rs1006469901 680 dbSNP
rs1365378431 682 dbSNP
rs1362176439 689 dbSNP
rs181589760 692 dbSNP
rs1296127680 695 dbSNP
rs1228105170 710 dbSNP
rs35740067 711 dbSNP
rs773582855 717 dbSNP
rs1228892724 721 dbSNP
rs931543727 722 dbSNP
rs45568343 724 dbSNP
rs1432412055 730 dbSNP
rs964693835 734 dbSNP
rs1322285815 736 dbSNP
rs1405487407 739 dbSNP
rs1387010705 744 dbSNP
rs944155838 759 dbSNP
rs974719054 763 dbSNP
rs1188068796 768 dbSNP
rs80194411 768 dbSNP
rs1041133130 780 dbSNP
rs902371864 789 dbSNP
rs564627650 796 dbSNP
rs954743542 818 dbSNP
rs1490876458 820 dbSNP
rs373248322 823 dbSNP
rs1274238534 826 dbSNP
rs988896747 845 dbSNP
rs1053589969 851 dbSNP
rs1470086489 854 dbSNP
rs1217888836 856 dbSNP
rs1365014120 860 dbSNP
rs913735378 870 dbSNP
rs762629723 873 dbSNP
rs1273951246 878 dbSNP
rs1436559077 879 dbSNP
rs774617613 880 dbSNP
rs1247940763 897 dbSNP
rs531689979 913 dbSNP
rs1428972069 927 dbSNP
rs1195345516 935 dbSNP
rs148705738 937 dbSNP
rs925216803 938 dbSNP
rs1412607088 966 dbSNP
rs1424706205 971 dbSNP
rs1164028546 973 dbSNP
rs562057015 983 dbSNP
rs937947050 985 dbSNP
rs1481542824 988 dbSNP
rs368956838 988 dbSNP
rs551546254 988 dbSNP
rs1003741090 994 dbSNP
rs1455440081 994 dbSNP
rs1253640701 995 dbSNP
rs1208456731 996 dbSNP
rs867675617 1000 dbSNP
rs1279802065 1001 dbSNP
rs1389219410 1008 dbSNP
rs961550962 1015 dbSNP
rs917588947 1018 dbSNP
rs1285882846 1023 dbSNP
rs1383441699 1028 dbSNP
rs949097978 1036 dbSNP
rs1047975332 1045 dbSNP
rs1373960435 1045 dbSNP
rs1299871817 1046 dbSNP
rs972887391 1050 dbSNP
rs1245124718 1051 dbSNP
rs766007287 1060 dbSNP
rs762303593 1067 dbSNP
rs554965660 1078 dbSNP
rs1207141165 1079 dbSNP
rs768069436 1084 dbSNP
rs1037938072 1096 dbSNP
rs530066183 1100 dbSNP
rs369057586 1104 dbSNP
rs45448098 1104 dbSNP
rs900728306 1107 dbSNP
rs548508455 1110 dbSNP
rs372989467 1116 dbSNP
rs944035740 1116 dbSNP
rs566730240 1118 dbSNP
rs1206021042 1119 dbSNP
rs1238360448 1119 dbSNP
rs1254215874 1123 dbSNP
rs1325206398 1137 dbSNP
rs758855307 1140 dbSNP
rs935378621 1141 dbSNP
rs1053621484 1146 dbSNP
rs893609119 1150 dbSNP
rs78501345 1154 dbSNP
rs185073065 1162 dbSNP
rs906213446 1163 dbSNP
rs1454416855 1170 dbSNP
rs1386727023 1178 dbSNP
rs1003196030 1183 dbSNP
rs1457977893 1185 dbSNP
rs1014513437 1191 dbSNP
rs190320430 1194 dbSNP
rs1020818995 1195 dbSNP
rs994514221 1196 dbSNP
rs1421371 1199 dbSNP
rs1463867831 1202 dbSNP
rs1247809415 1210 dbSNP
rs952909872 1216 dbSNP
rs979650117 1223 dbSNP
rs561065211 1232 dbSNP
rs1261917872 1268 dbSNP
rs1242048059 1284 dbSNP
rs986139691 1287 dbSNP
rs1315731065 1294 dbSNP
rs925129725 1298 dbSNP
rs959246109 1299 dbSNP
rs990697521 1314 dbSNP
rs1455321957 1316 dbSNP
rs1300985360 1330 dbSNP
rs917579467 1348 dbSNP
rs949089771 1352 dbSNP
rs1047460329 1353 dbSNP
rs181004810 1359 dbSNP
rs1018515888 1363 dbSNP
rs907639020 1366 dbSNP
rs142272845 1367 dbSNP
rs1314332331 1370 dbSNP
rs1457527803 1373 dbSNP
rs1366719028 1378 dbSNP
rs777470534 1385 dbSNP
rs567714542 1386 dbSNP
rs1348176881 1390 dbSNP
rs923896884 1400 dbSNP
rs535036331 1401 dbSNP
rs1317862587 1402 dbSNP
rs1241882745 1403 dbSNP
rs989555676 1404 dbSNP
rs996429072 1409 dbSNP
rs1340011672 1414 dbSNP
rs947892315 1416 dbSNP
rs1052053237 1417 dbSNP
rs1328420040 1419 dbSNP
rs1299538698 1420 dbSNP
rs890450398 1422 dbSNP
rs1386436253 1423 dbSNP
rs1346151560 1426 dbSNP
rs1010678100 1429 dbSNP
rs1428322924 1435 dbSNP
rs529960458 1436 dbSNP
rs1370532462 1437 dbSNP
rs1020304079 1439 dbSNP
rs1463914204 1448 dbSNP
rs1374424876 1455 dbSNP
rs1196241643 1456 dbSNP
rs1479909270 1467 dbSNP
rs1268930161 1474 dbSNP
rs906461823 1474 dbSNP
rs969177440 1476 dbSNP
rs1035995922 1478 dbSNP
rs1196145662 1482 dbSNP
rs1341140820 1484 dbSNP
rs1000292088 1490 dbSNP
rs755197760 1492 dbSNP
rs1232752824 1495 dbSNP
rs1032094663 1500 dbSNP
rs959234833 1502 dbSNP
rs765079709 1510 dbSNP
rs1408125164 1511 dbSNP
rs186035649 1517 dbSNP
rs1018836532 1524 dbSNP
rs965658828 1528 dbSNP
rs1172393067 1536 dbSNP
rs1468923123 1539 dbSNP
rs1429618459 1541 dbSNP
rs1482176190 1542 dbSNP
rs1471356645 1551 dbSNP
rs1231826197 1562 dbSNP
rs976967942 1563 dbSNP
rs752601242 1571 dbSNP
rs369767010 1583 dbSNP
rs983497493 1598 dbSNP
rs190888526 1599 dbSNP
rs1173946320 1600 dbSNP
rs1376929299 1610 dbSNP
rs1226638477 1612 dbSNP
rs941736876 1614 dbSNP
rs753664633 1617 dbSNP
rs117591321 1621 dbSNP
rs1368348944 1624 dbSNP
rs1241755209 1625 dbSNP
rs114374752 1627 dbSNP
rs866194795 1638 dbSNP
rs915314219 1645 dbSNP
rs10498771 1649 dbSNP
rs980646413 1664 dbSNP
rs927754397 1672 dbSNP
rs747159935 1676 dbSNP
rs1455320497 1679 dbSNP
rs1406551756 1681 dbSNP
rs1158660660 1688 dbSNP
rs939319530 1705 dbSNP
rs1366685538 1706 dbSNP
rs1182749640 1707 dbSNP
rs1036237042 1708 dbSNP
rs897521527 1710 dbSNP
rs1206990914 1713 dbSNP
rs1446669971 1715 dbSNP
rs930299507 1726 dbSNP
rs543551723 1730 dbSNP
rs1207024446 1731 dbSNP
rs890688545 1734 dbSNP
rs1354826680 1737 dbSNP
rs1247362049 1741 dbSNP
rs746479224 1753 dbSNP
rs1295902575 1757 dbSNP
rs1385353454 1757 dbSNP
rs1432373851 1759 dbSNP
rs1344286210 1766 dbSNP
rs45578734 1769 dbSNP
rs1402005501 1771 dbSNP
rs1388475867 1772 dbSNP
rs1042075403 1773 dbSNP
rs139299644 1778 dbSNP
rs780614907 1779 dbSNP
rs1018451970 1780 dbSNP
rs1247562204 1782 dbSNP
rs745500542 1793 dbSNP
rs1252103711 1797 dbSNP
rs894968290 1801 dbSNP
rs555353451 1802 dbSNP
rs1291134004 1804 dbSNP
rs774764265 1808 dbSNP
rs1362248539 1814 dbSNP
rs1272902955 1820 dbSNP
rs971018648 1822 dbSNP
rs1270473641 1823 dbSNP
rs983391132 1825 dbSNP
rs144326947 1829 dbSNP
rs1302021878 1831 dbSNP
rs1195391798 1833 dbSNP
rs552996402 1842 dbSNP
rs1367430214 1843 dbSNP
rs1409227000 1846 dbSNP
rs45536035 1846 dbSNP
rs1419976483 1852 dbSNP
rs973138438 1854 dbSNP
rs921705351 1856 dbSNP
rs960512708 1858 dbSNP
rs931740348 1863 dbSNP
rs1200290236 1864 dbSNP
rs1490974707 1874 dbSNP
rs971985876 1876 dbSNP
rs919189839 1894 dbSNP
rs987610672 1902 dbSNP
rs930538637 1905 dbSNP
rs1215921841 1922 dbSNP
rs867670500 1924 dbSNP
rs552383174 1926 dbSNP
rs1405075592 1927 dbSNP
rs946249913 1949 dbSNP
rs1463874185 1954 dbSNP
rs943166731 1955 dbSNP
rs1441392030 1960 dbSNP
rs1354855066 1962 dbSNP
rs564116426 1965 dbSNP
rs1040524550 1969 dbSNP
rs1412960322 1973 dbSNP
rs1428906767 1978 dbSNP
rs1177238822 1986 dbSNP
rs772496729 1996 dbSNP
rs901364860 2007 dbSNP
rs1409869464 2012 dbSNP
rs1367311258 2016 dbSNP
rs1042009766 2017 dbSNP
rs998338842 2019 dbSNP
rs904512809 2021 dbSNP
rs181300850 2026 dbSNP
rs1262195573 2028 dbSNP
rs892739113 2031 dbSNP
rs578037509 2033 dbSNP
rs1304267332 2039 dbSNP
rs1363194899 2041 dbSNP
rs1227667045 2051 dbSNP
rs1273986738 2052 dbSNP
rs1022331063 2061 dbSNP
rs1405604320 2063 dbSNP
rs773736903 2067 dbSNP
rs1055787093 2073 dbSNP
rs1309430721 2081 dbSNP
rs969793152 2089 dbSNP
rs549467056 2091 dbSNP
rs894539487 2095 dbSNP
rs1219145452 2099 dbSNP
rs1014305148 2109 dbSNP
rs760694469 2116 dbSNP
rs1444474806 2134 dbSNP
rs1203860315 2153 dbSNP
rs1468731124 2154 dbSNP
rs1462391006 2167 dbSNP
rs1258405694 2168 dbSNP
rs1214503819 2180 dbSNP
rs906406409 2181 dbSNP
rs185269722 2196 dbSNP
rs377071747 2209 dbSNP
rs1243698965 2218 dbSNP
rs951973643 2220 dbSNP
rs1315509703 2221 dbSNP
rs1215546016 2222 dbSNP
rs1454739061 2224 dbSNP
rs1383137330 2225 dbSNP
rs1288335754 2227 dbSNP
rs1005199496 2229 dbSNP
rs985103518 2231 dbSNP
rs1014873918 2234 dbSNP
rs1163223477 2241 dbSNP
rs1424618467 2246 dbSNP
rs910255818 2248 dbSNP
rs943008592 2250 dbSNP
rs572115341 2262 dbSNP
rs1040151523 2265 dbSNP
rs923028146 2266 dbSNP
rs1185417526 2271 dbSNP
rs1485875090 2277 dbSNP
rs1184925840 2281 dbSNP
rs1261975030 2281 dbSNP
rs545335732 2282 dbSNP
rs973043340 2286 dbSNP
rs60803626 2290 dbSNP
rs934374021 2296 dbSNP
rs370944499 2311 dbSNP
rs1052606522 2312 dbSNP
rs76447483 2327 dbSNP
rs1295202301 2329 dbSNP
rs1421247166 2341 dbSNP
rs747425172 2345 dbSNP
rs953072389 2350 dbSNP
rs1424555388 2364 dbSNP
rs987221206 2366 dbSNP
rs1163610031 2367 dbSNP
rs563883849 2368 dbSNP
rs566397854 2369 dbSNP
rs539737657 2370 dbSNP
rs111472465 2372 dbSNP
rs1011203747 2373 dbSNP
rs559433848 2373 dbSNP
rs561725590 2373 dbSNP
rs1372881810 2376 dbSNP
rs1169226452 2381 dbSNP
rs558379008 2384 dbSNP
rs905222048 2385 dbSNP
rs1196715480 2388 dbSNP
rs978064120 2396 dbSNP
rs926248937 2399 dbSNP
rs1224430630 2402 dbSNP
rs1337142234 2405 dbSNP
rs1430129983 2406 dbSNP
rs148774457 2422 dbSNP
rs1250557476 2430 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gaucacccauUUCUCCCUCUc 5'
                    |: ||||||| 
Target 5' ----------AGAAGGGAGAg 3'
 		1 - 11
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000544460.1 | 3UTR | AGAAGGGAGAGAGGUUUGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
203 hsa-miR-6867-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT078229 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT107799 SLC1A1 solute carrier family 1 member 1 2 2
MIRT115808 CAPN15 calpain 15 2 2
MIRT137570 RCOR1 REST corepressor 1 2 2
MIRT161372 MBNL1 muscleblind like splicing regulator 1 2 2
MIRT320477 HOXA10 homeobox A10 2 2
MIRT444449 PTPRG protein tyrosine phosphatase, receptor type G 2 2
MIRT461305 MRPS27 mitochondrial ribosomal protein S27 2 6
MIRT470306 PPP6R1 protein phosphatase 6 regulatory subunit 1 2 2
MIRT471679 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT475546 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 2 2
MIRT480901 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT489368 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT489557 PLD6 phospholipase D family member 6 2 2
MIRT494969 TMEM233 transmembrane protein 233 2 2
MIRT496634 SLC46A1 solute carrier family 46 member 1 2 2
MIRT500259 ZNF788 zinc finger family member 788 2 6
MIRT500272 ZNF781 zinc finger protein 781 2 8
MIRT500328 ZNF487P zinc finger protein 487 1 3
MIRT504012 ACSL6 acyl-CoA synthetase long chain family member 6 2 2
MIRT504830 EREG epiregulin 2 2
MIRT513588 DCTN6 dynactin subunit 6 2 2
MIRT520896 STMN1 stathmin 1 2 2
MIRT525275 C18orf32 chromosome 18 open reading frame 32 2 2
MIRT526166 ANKRD65 ankyrin repeat domain 65 2 2
MIRT526582 CCDC43 coiled-coil domain containing 43 2 2
MIRT527812 TMEM74B transmembrane protein 74B 2 2
MIRT528141 LRRC38 leucine rich repeat containing 38 2 2
MIRT529903 C1orf64 steroid receptor associated and regulated protein 2 4
MIRT531980 SLCO1B3 solute carrier organic anion transporter family member 1B3 2 2
MIRT532251 TBPL2 TATA-box binding protein like 2 2 2
MIRT534300 SKIDA1 SKI/DACH domain containing 1 2 2
MIRT534879 QKI QKI, KH domain containing RNA binding 2 2
MIRT538305 CSNK2A1 casein kinase 2 alpha 1 2 2
MIRT539385 ADRB1 adrenoceptor beta 1 2 2
MIRT541304 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT543960 RNF20 ring finger protein 20 2 2
MIRT544380 ZNF266 zinc finger protein 266 2 2
MIRT544451 KRBOX4 KRAB box domain containing 4 2 2
MIRT545783 ZNF791 zinc finger protein 791 2 4
MIRT548156 FRAT2 FRAT2, WNT signaling pathway regulator 2 2
MIRT556660 KMT2D lysine methyltransferase 2D 2 4
MIRT557715 GABARAPL1 GABA type A receptor associated protein like 1 2 2
MIRT562701 ZNF415 zinc finger protein 415 2 2
MIRT563050 ZNF138 zinc finger protein 138 2 2
MIRT564307 CCNT1 cyclin T1 2 2
MIRT568333 BACH1 BTB domain and CNC homolog 1 2 2
MIRT570864 ZNF525 zinc finger protein 525 2 2
MIRT570874 ZFP1 ZFP1 zinc finger protein 2 2
MIRT571516 ZNF625 zinc finger protein 625 2 2
MIRT572470 MTMR10 myotubularin related protein 10 2 2
MIRT572898 RUNDC3B RUN domain containing 3B 2 2
MIRT573084 APLN apelin 2 2
MIRT575251 Timp3 tissue inhibitor of metalloproteinase 3 2 2
MIRT575275 Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 2 2
MIRT607230 LINS lines homolog 1 2 4
MIRT611803 FCRL4 Fc receptor like 4 2 2
MIRT612669 POU2F1 POU class 2 homeobox 1 2 4
MIRT612739 MYOCD myocardin 2 2
MIRT613409 CDH8 cadherin 8 2 4
MIRT614007 PAOX polyamine oxidase 2 2
MIRT615188 CLUAP1 clusterin associated protein 1 2 2
MIRT616497 ATP6AP1L ATPase H+ transporting accessory protein 1 like 2 2
MIRT616524 URM1 ubiquitin related modifier 1 2 2
MIRT617066 SPIB Spi-B transcription factor 2 2
MIRT617813 EMX2 empty spiracles homeobox 2 2 2
MIRT619291 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT619375 KLHL12 kelch like family member 12 2 2
MIRT619499 TXLNB taxilin beta 2 2
MIRT619601 MKKS McKusick-Kaufman syndrome 2 2
MIRT619754 MYO1F myosin IF 2 2
MIRT619976 ZSCAN22 zinc finger and SCAN domain containing 22 2 2
MIRT620743 CCR5 C-C motif chemokine receptor 5 (gene/pseudogene) 2 2
MIRT620871 KCTD7 potassium channel tetramerization domain containing 7 2 2
MIRT621380 CLNK cytokine dependent hematopoietic cell linker 2 2
MIRT621511 ZNF638 zinc finger protein 638 2 2
MIRT621537 ZNF500 zinc finger protein 500 2 2
MIRT621772 TMEM87B transmembrane protein 87B 2 2
MIRT622193 SLC5A12 solute carrier family 5 member 12 2 2
MIRT622319 SEC63 SEC63 homolog, protein translocation regulator 2 2
MIRT622738 PITPNM3 PITPNM family member 3 2 2
MIRT622996 ONECUT3 one cut homeobox 3 2 2
MIRT625301 SHISA6 shisa family member 6 2 2
MIRT625637 KCNQ3 potassium voltage-gated channel subfamily Q member 3 2 2
MIRT627698 RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase 2 2
MIRT627751 RAD51L3-RFFL RAD51L3-RFFL readthrough 2 2
MIRT628438 ANTXR2 anthrax toxin receptor 2 2 2
MIRT635440 SLC25A44 solute carrier family 25 member 44 2 2
MIRT637166 TMEM50A transmembrane protein 50A 2 2
MIRT638207 SPTLC2 serine palmitoyltransferase long chain base subunit 2 2 2
MIRT639288 TFAP2A transcription factor AP-2 alpha 2 4
MIRT639398 NEURL1B neuralized E3 ubiquitin protein ligase 1B 2 2
MIRT641230 SEMA3E semaphorin 3E 2 2
MIRT641501 STC2 stanniocalcin 2 2 2
MIRT642577 PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2 2
MIRT642735 TDRD6 tudor domain containing 6 2 2
MIRT644001 PPP1R3G protein phosphatase 1 regulatory subunit 3G 2 2
MIRT644210 CBS cystathionine-beta-synthase 2 2
MIRT645405 FAM110A family with sequence similarity 110 member A 2 2
MIRT645685 TBC1D13 TBC1 domain family member 13 2 2
MIRT645699 C1orf50 chromosome 1 open reading frame 50 2 2
MIRT645761 SURF6 surfeit 6 2 2
MIRT645826 INADL PATJ, crumbs cell polarity complex component 2 2
MIRT645914 PLXNA3 plexin A3 2 2
MIRT646167 PTPN14 protein tyrosine phosphatase, non-receptor type 14 2 2
MIRT646634 COA4 cytochrome c oxidase assembly factor 4 homolog 2 2
MIRT647547 CYP2B6 cytochrome P450 family 2 subfamily B member 6 2 2
MIRT648262 ZNF582 zinc finger protein 582 2 2
MIRT648385 ZNF22 zinc finger protein 22 2 2
MIRT648629 LEMD2 LEM domain containing 2 2 2
MIRT649353 SLC27A2 solute carrier family 27 member 2 2 2
MIRT649395 SH2D4A SH2 domain containing 4A 2 2
MIRT650241 CD68 CD68 molecule 2 2
MIRT650379 PTGIS prostaglandin I2 synthase 2 2
MIRT650705 KRT32 keratin 32 2 2
MIRT650854 UNC13D unc-13 homolog D 2 2
MIRT651042 ZNF644 zinc finger protein 644 2 2
MIRT651102 ZNF48 zinc finger protein 48 2 2
MIRT651130 ZNF398 zinc finger protein 398 2 2
MIRT652089 TSKU tsukushi, small leucine rich proteoglycan 2 2
MIRT652200 TRIM33 tripartite motif containing 33 2 2
MIRT652422 TMEM239 transmembrane protein 239 2 2
MIRT652755 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT653201 SP9 Sp9 transcription factor 2 2
MIRT653338 SMG7 SMG7, nonsense mediated mRNA decay factor 2 2
MIRT653715 SLC25A32 solute carrier family 25 member 32 2 2
MIRT654456 RAP2B RAP2B, member of RAS oncogene family 2 2
MIRT654499 RABIF RAB interacting factor 2 2
MIRT654678 PSMB5 proteasome subunit beta 5 2 2
MIRT655162 PHF20L1 PHD finger protein 20 like 1 2 2
MIRT655540 PADI2 peptidyl arginine deiminase 2 2 4
MIRT655850 NFE2L1 nuclear factor, erythroid 2 like 1 2 2
MIRT656248 MEX3A mex-3 RNA binding family member A 2 2
MIRT656581 LSAMP limbic system-associated membrane protein 2 2
MIRT657597 GRID1 glutamate ionotropic receptor delta type subunit 1 2 2
MIRT657824 GJD3 gap junction protein delta 3 2 2
MIRT658466 FAM102B family with sequence similarity 102 member B 2 2
MIRT659083 DENR density regulated re-initiation and release factor 2 2
MIRT659196 CYBB cytochrome b-245 beta chain 2 2
MIRT659558 CGGBP1 CGG triplet repeat binding protein 1 2 2
MIRT659860 CAPRIN1 cell cycle associated protein 1 2 2
MIRT660172 BNC2 basonuclin 2 2 2
MIRT660626 ANKRD52 ankyrin repeat domain 52 2 2
MIRT660917 ADAM19 ADAM metallopeptidase domain 19 2 2
MIRT660979 ABHD2 abhydrolase domain containing 2 2 2
MIRT661564 EPHX2 epoxide hydrolase 2 2 2
MIRT662214 CCRL2 C-C motif chemokine receptor like 2 2 2
MIRT662246 C15orf52 chromosome 15 open reading frame 52 2 2
MIRT662560 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT662591 MAGEB4 MAGE family member B4 2 2
MIRT663294 TECPR2 tectonin beta-propeller repeat containing 2 2 2
MIRT663437 FBXO2 F-box protein 2 2 2
MIRT663811 RNF128 ring finger protein 128, E3 ubiquitin protein ligase 2 2
MIRT663821 NLRP12 NLR family pyrin domain containing 12 2 2
MIRT665959 SZRD1 SUZ RNA binding domain containing 1 2 2
MIRT666115 SRRM4 serine/arginine repetitive matrix 4 2 2
MIRT667448 MAPK14 mitogen-activated protein kinase 14 2 2
MIRT669330 BSND barttin CLCNK type accessory beta subunit 2 2
MIRT669409 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT669641 ACSBG1 acyl-CoA synthetase bubblegum family member 1 2 2
MIRT672663 GTF2H5 general transcription factor IIH subunit 5 2 2
MIRT673266 RUNDC1 RUN domain containing 1 2 2
MIRT676995 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT679290 SSBP2 single stranded DNA binding protein 2 2 2
MIRT687508 NCKAP1 NCK associated protein 1 2 2
MIRT698932 SPATA2 spermatogenesis associated 2 2 2
MIRT700852 PERP PERP, TP53 apoptosis effector 2 2
MIRT702426 KIAA1958 KIAA1958 2 2
MIRT703939 EPB41L1 erythrocyte membrane protein band 4.1 like 1 2 2
MIRT708962 SLC12A3 solute carrier family 12 member 3 2 2
MIRT709742 UBD ubiquitin D 2 2
MIRT709946 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT711121 CYYR1 cysteine and tyrosine rich 1 2 2
MIRT711217 RETSAT retinol saturase 2 2
MIRT711576 ASPA aspartoacylase 2 2
MIRT711599 LHX5 LIM homeobox 5 2 2
MIRT712232 RCC2 regulator of chromosome condensation 2 2 2
MIRT713317 TMEM44 transmembrane protein 44 2 2
MIRT713510 PAFAH2 platelet activating factor acetylhydrolase 2 2 2
MIRT713543 GJB1 gap junction protein beta 1 2 2
MIRT713621 MED8 mediator complex subunit 8 2 2
MIRT714988 TSPAN11 tetraspanin 11 2 2
MIRT715449 PTCD1 pentatricopeptide repeat domain 1 2 2
MIRT715575 ATP5J2-PTCD1 ATP5J2-PTCD1 readthrough 2 2
MIRT715771 DDX42 DEAD-box helicase 42 2 2
MIRT715887 GNG2 G protein subunit gamma 2 2 2
MIRT716091 HARS histidyl-tRNA synthetase 2 2
MIRT717403 ZCCHC24 zinc finger CCHC-type containing 24 2 2
MIRT717965 PXMP4 peroxisomal membrane protein 4 2 2
MIRT718324 METTL7A methyltransferase like 7A 2 2
MIRT718628 DIP2A disco interacting protein 2 homolog A 2 2
MIRT719213 CAMK4 calcium/calmodulin dependent protein kinase IV 2 2
MIRT719234 CYSLTR2 cysteinyl leukotriene receptor 2 2 2
MIRT719817 LRRC4 leucine rich repeat containing 4 2 2
MIRT719978 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT720480 TMEM178B transmembrane protein 178B 2 2
MIRT720713 RAPGEF6 Rap guanine nucleotide exchange factor 6 2 2
MIRT721006 ZNF619 zinc finger protein 619 2 2
MIRT721741 SDK2 sidekick cell adhesion molecule 2 2 2
MIRT723547 ZDHHC22 zinc finger DHHC-type containing 22 2 2
MIRT723596 FKRP fukutin related protein 2 2
MIRT723746 AIFM2 apoptosis inducing factor, mitochondria associated 2 2 2
MIRT724784 C1D C1D nuclear receptor corepressor 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6867-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)

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