miRTarBase - #MIRT653618


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pre-miRNA Information
pre-miRNA hsa-mir-497   
Genomic Coordinates chr17: 7017911 - 7018022
Synonyms MIRN497, hsa-mir-497, MIR497
Description Homo sapiens miR-497 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-497-3p
Sequence 64| CAAACCACACUGUGGUGUUAGA |85
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 17 - 7017957 29233923 MiREDiBase
A-to-I 4 17 - 7017956 29233923 MiREDiBase
A-to-I 20 17 - 7017940 24964909, 25521855, 27229138, 29165639, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1413601274 5 dbSNP
rs1028648384 6 dbSNP
rs1479092960 9 dbSNP
rs1261056598 10 dbSNP
rs997278260 11 dbSNP
rs1324708562 13 dbSNP
rs755634302 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SLC30A4   
Synonyms ZNT4, znT-4
Description solute carrier family 30 member 4
Transcript NM_013309   
Expression
Putative miRNA Targets on SLC30A4
3'UTR of SLC30A4
(miRNA target sites are highlighted)		 
>SLC30A4|NM_013309|3'UTR
   1 TTTTATGTATTTTGGGAACTCCTGCCTTATTTATCCTGCAGTCACAGACTTGAGAGCAATAAATGCAAACCTAAATGAGA
  81 AAATGGAATCCCTGACAGCTGTGTCCGTATCAAGCATCAGTCTCTCAAACAGTTGCCCCAGCCTGACAGTGCTAGTCTCT
 161 GTTTAATGGTAAAAGGAGACTTTGCCATAATTTTCAGATGAAGATGTTTCCCAAACACTGTTTACAGAATGAGATGTGAC
 241 TCTACAGATACCTCATAGAAGACAATCCAAGATCATACTTCATTAACTTGACAGAGTACGTGTCTTAAAGGAAGCATCAA
 321 GAATTCAATATTTGCATTTAAAAATACTTTTTAAGGCCATTTTATATTAAGCCAGTGCTGGAAAACTGAATTTTTTTTAT
 401 TATGTATAATAATCTCGACACCCAGCTTCTGGAATTGCTGCTTTCTTTTTACAGAAATTACTACCCAACAGATTTCAGGA
 481 AGTACTAGTAGTTATCCCAAAAGTGGAATAAGCATGTATTCCTAAGTGTTTCAGAAATGTTTTATTTCACACATAAGTCT
 561 TAATGTTATTGTTATGATTATACTTTATAAACAACCTTTTCCAGATGCTACAGGGTTTTGAATCTCAAAGTTAACATTTT
 641 TCATTATTTGTAATCTTAGAACCAAATCTTTATTTATTGTGGTCACTGTTATTAAATGATTTAGGAAATACTTTCAATAT
 721 TATTCTGAATGGCTGAAGTTAGTCTTAAACTCAAATTACTATATGATGATTTAAAACAAAATAAAAGAGCGAGGATGGGG
 801 GTTGGAGTTTCAGGTTTATGTCTTCCCGACATCACTTTTATCATTCATGAAATTGTCTTAAAAAAGCAAGAGACTGCAAA
 881 ATGTAAACAGTAATCTTCTGTCCCTTTAAGAACTGCCAACAATTTGTACAAAAAATGTGGTACGTTGGTTCCTGCCTCCA
 961 CTCCAGGTCATCTGTGTGTTTAGCCTTTCAGGGTAAACTCTAGAGGGTTCAGTTTATAATTCCCACCTTTCACATATAGT
1041 TCAACAACATTAATCCAGAGAGAATTTTATGTTTTATGATATGGGTTATGTTTTATTATATATTTTATGTTTTATGATAT
1121 GGGTTAGGGATTCTCCATGGACTCCAGAAACCCTAAAATACAATTTTGAGGTTTTCCAATAATACCATAGCAGAAATGTC
1201 CAAGGGGTTGGGGGAAGATATTACTTTGAGAAAACAGAAATGTAAAGGATTTTTGACCTTATATATGTGTGTGGTTTTGT
1281 TTTTGTTTTTGTTCTTGAGAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGACCTCTGCTCACTGTAACCT
1361 CTGCCTCCTGGGTTCAAGTGATTCTTCTGCCTCAGCCTCCCAACTAGCTGGGACTACAGGTACACCACACCCAGCTCATT
1441 TTTTTGTATTTTTAGTAGAGACAGGGTTTTGCCACATTGGCCTGTCTGGTCTTGAACTCCTGACCTCAGGTGATCCGCCT
1521 GCCTTGGCCTTCCAGAGTGCTGGGATTACAGCATGAGCCACCATGCCTGGCCTGTATGTGTGTGTTTTAAAGCACTAGAT
1601 AGGGATGGACATTAAATCTGTGTTGCAGGGAAACTAAACAGAGGTTTCCAAACTGAAGGCAACCTAATTGTAAATGCCTG
1681 TGTTAAAGAGGCAGCTTGACTGTTCATGTTTCATTTTGCAACCATTGGTTTTGAGATTATCTTTTATGCACATTTGGAGT
1761 CCCTTTTCAACAGTGACAGTTTCTTACACGAAGAATGGATATGGTTATTGGGCTCCTCTAAGAATCAGAGTAGGGTAACA
1841 ATGTACCAGGCAAATTGTAAGTTGAAATTCTAGATAAGCATGCAGATGACTTACAATATAAATGAAGAATAGGAAACATT
1921 TTATCTTCTTACCAAGTACCTTACTATAAGTAAACCTAAGATAAGAAAACCCAGATTTACCTATAAGATTGTTGGGAGTT
2001 AATGGTGTCAATAAAAGGATTGATGGTCCCTCTAATGAAACCCAGTAGATGTTTGTTGAATTGAACTGAAAATTTATGTG
2081 GCCAGACACAGTGGCTCATGCCTGTAATCTCAGCATTTGGGGAGGCAAAGGTGGAAGTATCCCTCGAGGCCAAGAGTTCA
2161 TGACCAGCCTGGTCTTTTGTAGAGACCCTGTCTCTACAAAAATATAAAAATCAGCCAGGCGTCGTGCACACCTGTAGTAT
2241 CAGCTACTTGTAAGGCTGTGGCAGAAGTGCTTTAGCCCAGGAGGTTGAGGCTGCAGTGAGCCATGTCCACACCATTGCAC
2321 TGCAGCCTGAGTAACAAAATGAGACCCTATCTCAAAAACAAAAAGGAAAAGAAAATATACATGATGGGATTCCTATTGTG
2401 AAGTCATTTAAAATAATGACTTGAATTTCTCAGAAATTTCAGGAGCATATAAACTATTTAAATCAAAATATTCTTACATA
2481 TAGAAACCAAGTAAGAATAAATGAGAGATATTTCAGTGGACATCTGGACATATTTATGGACTTTGAGTATCTAGCAAGTA
2561 GAAAGGAAAAAAATATTCATCATACTCTAATCATTTTTTTATATCTATTGAGCTTGTTTCTTGTAAACTTTTCTTTATCT
2641 TATAAAGGCATATCTCGCTTTTGTATCGACCTGTTCCTTAAAAAATGTATTTGATAAAACAGGCTAAAATTCATTTGAGT
2721 ATTGAAAAGAATTCTTTTTTTTTTTTTAAGATGGTGTCTCACTGTCACCCAGGCTGGAGTGCAGTGGCACAGTTGGGCTC
2801 ACTGCAGCCTCTGCCTCCCAGGCTCAAGTGGTCCTCCCATCTCAGCCTCCCAAGTAGCTGGTACCACAGGCATGCACCAC
2881 CACACCCAGCTAATTTTTTGTATTTTTGGTAGACACAGTGTTTCACCATGTTGCCCAGGCTGGTCTTGAACTCCTGAGCT
2961 CAAGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGCTTATGGGCATGAACCACTGTGCCCAGCCAAAAAGAATCCTT
3041 TTGTAAAATACAGAAACACTGCAAACCTTTGTAAATCTTTTTTTTTTTTTTTTTTTTTTTTTTTTAATGAGATGGGGTCT
3121 CCCTATGTTGCCCAGGCTGGTCTTGAGCTCCTGGGCTCAAGAAATCCTTCCACCTCGGGCTCCCAAAGTGCTGAGATTAC
3201 AGGGTGTGAGCTACCGCACCCAGCCATGAAAACTTCTGTAAATCTTAACTATCGTGTTCTGCTTAAAGTGAGGTACACAT
3281 AAAGTTTCCTGTGCTTTGTTTTTGTAGGAAAAAGTACATAGTTTGTATCTTTACCTTACGGAGTCTATGAGATTTGAGAA
3361 TTTGATTTCACTTTTTGTAACTTAACCCACAGAAAAGGACATTAACTTAGCAGATAGGACCAAGGACTGAATGACTTCTG
3441 ACAAAAAGCGTTTGGTCTATCCTTCACTTGTTGAGCTACAACCATGCATTACACTTCTCAGCTGAGCTCTCAAAGAGCTC
3521 TATGCCCTGTGAAAAGCAGTGGCTGAGTTGGATGAACACATAGCATTATTAATTTTGCACTGGGAAAACAGATTATGACA
3601 GGACCACAGACCACAATATAAAAACTTGGCAGTTCTTTGGTGTGATATATTTTAATTAGTATTTGCAAATAATCAGAGTT
3681 ACTTGTGTACATAAACGTGTGTTTCACAACTATGGCCAGATGCAACCTTTTGGTCTGTTTCAGGAAAAGACCTATTATTC
3761 CACTAACAATTATGCTGCCTTAGAAACATAATGGGAGTGTAATTGAAGAAAGCATGTCTCAGAAGGTTTTGATATGCAGA
3841 ACTGGAAGCTATTGTAATTCCTACATACATTTCCATTAGCTATGCCTTATGTAATGTGAGTGCAGATTTTTACAACTTAG
3921 AGTTCCCATCAGTGTTTTTTTGCCACATCACCGGGTTTCTTATTTTACTGTTTTCTTTTCAACTTTGGGTGCTTTATTTC
4001 CATTCTCTAAAACTAAGTTTCTTGCTCTTACGAGACTTAGTGTTCCTTTTGAACCCAGGTGTTCCACCTGACAGTGTTTG
4081 TCTTTCATAGACTTTCCAGAATAGACATAGTCAAGATCAGACACGTGAGCTTCTCTCTCATTTTAATGTGAGGAAAATCA
4161 TCTTTCAGAGACAAGGCACCGCTTAGAAATGTATGTCCAGGTATGAAAGAACCTTTTTAAAATGGCTGGTTGTTCCAGAT
4241 CCAGATTTCTCTGCACACTGGACTTCGTAGAGTAAGTGTGGTAGACAAAGAGACTACACTGCACAACCACCAGTGAATAT
4321 CATTGCTAAGAAGACTTTGGGTCGTGTTTCTCAGCCACTCTCACAGCTTTTGTAGACTTATTTGATTTTGAAACAAGCAG
4401 TTAGCTAAATCTATTTTCCTTTTATGCATATATGTTAATTGGCTCAACTTAATATGGTGTTCTTACAGAATATGAGCCCA
4481 TTTGAAATAAGGTTTTAGGCAATTTTGCTGTTGGCTCTGATTTGTATATAGCAAATTTAAAGTTACAGAGTGTTTCCTAG
4561 ATAGAAGATTAGTTCATTTGGTTCATTTTGTCTTTGAAGCAAGCCAAGCTCATGAGCCAGTTGGTTATTTGTCATAAATG
4641 AACACCCATCACTATATGCTATGTTGAGGGGAGGCAAGTCTGATCTTCGAATAATTGATAAAGTTTAATATCTTTGTAGC
4721 CAAAATACAATTTGCAAACCCTAACTCCAGATGTGTCGTATGAATCTTGACAACCAGGTCTTGAGATTTGTTTTACTGAT
4801 TGCCAATCAGGTATATTATTTGTGATGTTCGTGGGAGCATGCAAATTAGAAGACAGTGTTGTGGGAGTTCCTCAGTATTG
4881 AATTACATGTGTGCACTCAGGCCTGCCAGTCACTGAATTCTGACTTGTAAAGGGTTTAACCTGCTGTTCCAATCATTGAG
4961 GACCAATTTGCTTTTTGATAAGATTGGAAAACATTTATGGAGACTTTCCCAGTTAAATCTATGACAGTGTCCACTTAAAT
5041 AGTGCAATTTAGTATATTCTCAGATAACTGCAACACAAAATTGAAATGTGCCAGTATGTCATCTTTCTACCTGGAAGATA
5121 CTGTATATTTGGAAAGTTTATGCTTCTCTCAATAAATACATGTTATTAAATAAGCCATATCACAGTTTAAGAAATTGTAT
5201 ATACTTTATCATATGCCCTTTCAGAAACCAGGTATTTTGCATATGATTGATTTTAGAAAGATTTTGAAGCTGGGGTTTGT
5281 CCATGTTAATTAAGATCAAAGTATATATATATATATATATATGTGCTGTATTTGCAACTTTCACATTGTAATTTCCTATA
5361 CACTTATTAAAGTATTGTTTTGCCATGTGGTTTATTAAATAAAAATGTACAGTCTCTTAAATATCTGCTCTTTTTATTAA
5441 GTAATATTAGTAGGCCTAAAAACATTGTTCTTAAAAGAAAATCTTTTATAATTATAATGTCATTTTATAATGCCCTCTTA
5521 TATGTTTAAGAAATAAAACTGAAAAAAATCAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agAUUGUGGUGU-----CACACCAAAc 5'
            |:|| ::|:|     ||||||||| 
Target 5' ttTGACCTTATATATGTGTGTGGTTTt 3'
 1252 - 1278 160.00 -15.30
2 
miRNA  3' agauuGUGGUGUCACACCAAAc 5'
               ::|||   |||||||| 
Target 5' tgtttTGCCA---TGTGGTTTa 3'
 5376 - 5394 150.00 -10.40
3 
miRNA  3' agaUUGUGGUGUCACACCAAAc 5'
             ||:|| |:  || ||||| 
Target 5' taaAATACAATTTTGAGGTTTt 3'
 1154 - 1175 131.00 -7.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30129967 9 COSMIC
COSN19648781 17 COSMIC
COSN31593622 25 COSMIC
COSN24305234 34 COSMIC
COSN30483309 35 COSMIC
COSN23052969 41 COSMIC
COSN26509227 80 COSMIC
COSN5754693 103 COSMIC
COSN31521117 136 COSMIC
COSN31513495 185 COSMIC
COSN31555285 231 COSMIC
COSN26603935 258 COSMIC
COSN22747956 534 COSMIC
COSN27747427 790 COSMIC
COSN31606143 943 COSMIC
COSN32057498 1039 COSMIC
COSN26595831 1114 COSMIC
COSN22554223 1248 COSMIC
COSN23528969 1630 COSMIC
COSN7045807 1639 COSMIC
COSN18914366 2159 COSMIC
COSN25183769 2221 COSMIC
COSN25054101 2464 COSMIC
COSN9090501 2483 COSMIC
COSN20588855 2633 COSMIC
COSN26455600 2833 COSMIC
COSN19124392 3325 COSMIC
COSN28118089 3931 COSMIC
COSN22101381 4139 COSMIC
COSN16882701 4354 COSMIC
COSN28428391 5165 COSMIC
COSN27578613 5301 COSMIC
COSN23353592 5302 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1486175085 5 dbSNP
rs1243734496 7 dbSNP
rs1342615063 8 dbSNP
rs1196557451 14 dbSNP
rs1153829 17 dbSNP
rs1022471388 22 dbSNP
rs755392997 33 dbSNP
rs747296207 35 dbSNP
rs780297007 37 dbSNP
rs1294280042 39 dbSNP
rs1430899492 39 dbSNP
rs1455769576 63 dbSNP
rs539591897 68 dbSNP
rs959484518 71 dbSNP
rs1390327466 77 dbSNP
rs1430818044 102 dbSNP
rs6413526 103 dbSNP
rs1034204246 106 dbSNP
rs1369315682 107 dbSNP
rs1459879856 114 dbSNP
rs146894383 116 dbSNP
rs1235166716 118 dbSNP
rs1203044371 120 dbSNP
rs928861387 122 dbSNP
rs1227482221 130 dbSNP
rs981663916 132 dbSNP
rs1482982734 133 dbSNP
rs1323479160 141 dbSNP
rs906546295 154 dbSNP
rs1264749731 155 dbSNP
rs775106134 169 dbSNP
rs755785214 186 dbSNP
rs1213420255 187 dbSNP
rs1484369986 187 dbSNP
rs1206324786 197 dbSNP
rs1023084122 217 dbSNP
rs149619863 218 dbSNP
rs1188372164 219 dbSNP
rs534631077 235 dbSNP
rs957331503 238 dbSNP
rs1166117279 241 dbSNP
rs1300144348 246 dbSNP
rs1368342343 248 dbSNP
rs1456510751 251 dbSNP
rs1322642908 258 dbSNP
rs527461512 263 dbSNP
rs78134811 267 dbSNP
rs1389716417 270 dbSNP
rs1434622234 271 dbSNP
rs1318727338 272 dbSNP
rs994092838 277 dbSNP
rs1374879055 286 dbSNP
rs1228603695 287 dbSNP
rs897097058 289 dbSNP
rs1038203182 293 dbSNP
rs941215269 294 dbSNP
rs1229769938 300 dbSNP
rs776985723 300 dbSNP
rs1279169647 302 dbSNP
rs889527317 308 dbSNP
rs1268171326 311 dbSNP
rs1464012065 314 dbSNP
rs1049479992 319 dbSNP
rs933632589 321 dbSNP
rs922273234 334 dbSNP
rs1484450855 365 dbSNP
rs901518200 366 dbSNP
rs1375945167 380 dbSNP
rs1413795337 381 dbSNP
rs562038139 387 dbSNP
rs1018832746 392 dbSNP
rs1007479363 394 dbSNP
rs548220421 398 dbSNP
rs1357700533 399 dbSNP
rs930514859 399 dbSNP
rs898549335 402 dbSNP
rs915520673 403 dbSNP
rs989647705 411 dbSNP
rs959835261 416 dbSNP
rs926700219 417 dbSNP
rs982212206 421 dbSNP
rs1411559519 422 dbSNP
rs1288867680 425 dbSNP
rs531624277 429 dbSNP
rs939978889 432 dbSNP
rs1280371169 444 dbSNP
rs368791964 449 dbSNP
rs948962036 468 dbSNP
rs916187536 469 dbSNP
rs1175508114 479 dbSNP
rs13379863 485 dbSNP
rs1253078921 488 dbSNP
rs970678838 491 dbSNP
rs990700291 494 dbSNP
rs1472570380 504 dbSNP
rs374518063 507 dbSNP
rs1190580237 514 dbSNP
rs1415225027 519 dbSNP
rs993535523 532 dbSNP
rs1341026006 537 dbSNP
rs961299369 538 dbSNP
rs1308575456 539 dbSNP
rs977199712 553 dbSNP
rs1276079605 554 dbSNP
rs1367930124 557 dbSNP
rs965823516 560 dbSNP
rs138258443 569 dbSNP
rs570363418 573 dbSNP
rs1207663635 579 dbSNP
rs750053062 602 dbSNP
rs1276042710 608 dbSNP
rs1483012797 610 dbSNP
rs1281561662 626 dbSNP
rs1248504619 635 dbSNP
rs1478368148 635 dbSNP
rs1190834560 638 dbSNP
rs1423258492 643 dbSNP
rs1451163356 649 dbSNP
rs1005353846 650 dbSNP
rs1027588516 652 dbSNP
rs1325391997 656 dbSNP
rs1349997623 660 dbSNP
rs1435039495 662 dbSNP
rs545744087 667 dbSNP
rs1272727813 669 dbSNP
rs191217663 672 dbSNP
rs1049427911 683 dbSNP
rs1036645456 684 dbSNP
rs1342135569 688 dbSNP
rs1194607900 692 dbSNP
rs150122492 707 dbSNP
rs540841523 715 dbSNP
rs1452271289 717 dbSNP
rs574959723 718 dbSNP
rs768913063 730 dbSNP
rs1004293612 743 dbSNP
rs546417201 747 dbSNP
rs555131739 748 dbSNP
rs1378179313 756 dbSNP
rs1289174412 760 dbSNP
rs1474282772 765 dbSNP
rs900966762 778 dbSNP
rs111284170 782 dbSNP
rs1404301769 789 dbSNP
rs767053110 790 dbSNP
rs576007970 791 dbSNP
rs551762076 794 dbSNP
rs1045693097 806 dbSNP
rs1190696710 814 dbSNP
rs1422520163 819 dbSNP
rs1225626612 824 dbSNP
rs544301455 826 dbSNP
rs539399375 828 dbSNP
rs1357666783 833 dbSNP
rs1227853794 835 dbSNP
rs938170687 838 dbSNP
rs1187427395 844 dbSNP
rs1271330350 846 dbSNP
rs926787609 849 dbSNP
rs1466274789 852 dbSNP
rs916135162 853 dbSNP
rs982310288 854 dbSNP
rs771673440 860 dbSNP
rs1247576486 866 dbSNP
rs1445076748 872 dbSNP
rs1189339645 875 dbSNP
rs1238044012 877 dbSNP
rs1054722698 888 dbSNP
rs1162230684 892 dbSNP
rs1413559503 895 dbSNP
rs187910063 902 dbSNP
rs1157964972 903 dbSNP
rs1382311457 909 dbSNP
rs1207619018 915 dbSNP
rs1380952241 920 dbSNP
rs1336523630 921 dbSNP
rs1341646685 926 dbSNP
rs1447976517 935 dbSNP
rs924799860 936 dbSNP
rs2433600 937 dbSNP
rs1274431807 940 dbSNP
rs140773691 943 dbSNP
rs1267804384 944 dbSNP
rs182655205 958 dbSNP
rs1296067593 960 dbSNP
rs1279040720 965 dbSNP
rs1441584063 976 dbSNP
rs1016826690 981 dbSNP
rs1217924961 984 dbSNP
rs1472666969 993 dbSNP
rs1364414562 1000 dbSNP
rs146439024 1012 dbSNP
rs1361745784 1017 dbSNP
rs953036252 1022 dbSNP
rs1403400147 1028 dbSNP
rs1434556294 1029 dbSNP
rs1395324931 1033 dbSNP
rs1352850877 1034 dbSNP
rs1027949705 1036 dbSNP
rs1334250331 1037 dbSNP
rs531509684 1037 dbSNP
rs1235727410 1047 dbSNP
rs375489391 1062 dbSNP
rs1344036603 1068 dbSNP
rs748900607 1070 dbSNP
rs900914664 1078 dbSNP
rs1483324354 1079 dbSNP
rs1014749717 1082 dbSNP
rs1003357658 1086 dbSNP
rs868240598 1090 dbSNP
rs907273366 1095 dbSNP
rs1376661335 1098 dbSNP
rs1368367293 1120 dbSNP
rs1172155588 1127 dbSNP
rs777569091 1136 dbSNP
rs796212548 1168 dbSNP
rs1012836314 1174 dbSNP
rs1394457572 1181 dbSNP
rs1388009226 1187 dbSNP
rs1302262050 1208 dbSNP
rs1370523083 1210 dbSNP
rs1231858468 1215 dbSNP
rs1299521212 1219 dbSNP
rs1342549750 1221 dbSNP
rs1009207421 1232 dbSNP
rs568770173 1240 dbSNP
rs1489185526 1242 dbSNP
rs1054003931 1247 dbSNP
rs1209902734 1250 dbSNP
rs1254361561 1257 dbSNP
rs936257270 1262 dbSNP
rs924885276 1265 dbSNP
rs1392440207 1280 dbSNP
rs1450433591 1283 dbSNP
rs938271831 1285 dbSNP
rs1488141216 1288 dbSNP
rs1041871205 1291 dbSNP
rs1371787402 1294 dbSNP
rs376032255 1298 dbSNP
rs1229418161 1299 dbSNP
rs944872172 1303 dbSNP
rs1394087641 1313 dbSNP
rs190854485 1322 dbSNP
rs1322764950 1324 dbSNP
rs752676081 1327 dbSNP
rs949559887 1337 dbSNP
rs532341305 1338 dbSNP
rs1323424541 1347 dbSNP
rs1244928970 1353 dbSNP
rs972574574 1358 dbSNP
rs1331962854 1359 dbSNP
rs879481549 1360 dbSNP
rs920268290 1364 dbSNP
rs1465642449 1365 dbSNP
rs145249111 1367 dbSNP
rs909211584 1379 dbSNP
rs540404394 1390 dbSNP
rs140213616 1392 dbSNP
rs1028222063 1393 dbSNP
rs1417288818 1394 dbSNP
rs976544284 1397 dbSNP
rs965197199 1400 dbSNP
rs1161669766 1402 dbSNP
rs1389644969 1416 dbSNP
rs1429853078 1419 dbSNP
rs981881589 1427 dbSNP
rs1020638214 1430 dbSNP
rs1396556276 1432 dbSNP
rs1024305420 1435 dbSNP
rs1009734636 1438 dbSNP
rs1353026249 1444 dbSNP
rs893439931 1446 dbSNP
rs60483699 1448 dbSNP
rs1001899086 1456 dbSNP
rs561372114 1459 dbSNP
rs1315959201 1463 dbSNP
rs894584491 1465 dbSNP
rs1454470783 1489 dbSNP
rs544748305 1499 dbSNP
rs1046693503 1512 dbSNP
rs1432082067 1515 dbSNP
rs949507625 1516 dbSNP
rs576019634 1517 dbSNP
rs903411270 1517 dbSNP
rs944820084 1525 dbSNP
rs1157126418 1528 dbSNP
rs890629775 1529 dbSNP
rs1036413500 1534 dbSNP
rs1050618489 1535 dbSNP
rs1421876684 1539 dbSNP
rs931707945 1545 dbSNP
rs1411195337 1555 dbSNP
rs942100935 1574 dbSNP
rs909339766 1578 dbSNP
rs1288405965 1580 dbSNP
rs1482002261 1580 dbSNP
rs920363894 1588 dbSNP
rs1302871446 1605 dbSNP
rs1273683959 1608 dbSNP
rs1211290963 1610 dbSNP
rs1348928834 1618 dbSNP
rs986519590 1624 dbSNP
rs1484961394 1625 dbSNP
rs1305880459 1635 dbSNP
rs932013315 1636 dbSNP
rs940363470 1641 dbSNP
rs1469654015 1643 dbSNP
rs907751413 1647 dbSNP
rs921152128 1659 dbSNP
rs976658807 1660 dbSNP
rs1433615083 1662 dbSNP
rs1023416446 1666 dbSNP
rs1373600295 1671 dbSNP
rs375929054 1700 dbSNP
rs1021216678 1706 dbSNP
rs530351528 1707 dbSNP
rs1033528868 1711 dbSNP
rs958007953 1719 dbSNP
rs761963904 1725 dbSNP
rs1002246708 1727 dbSNP
rs1170445429 1728 dbSNP
rs545837845 1730 dbSNP
rs904876007 1741 dbSNP
rs1231294899 1746 dbSNP
rs1364293521 1747 dbSNP
rs1274237853 1749 dbSNP
rs890742186 1771 dbSNP
rs1025191461 1773 dbSNP
rs1248740407 1783 dbSNP
rs1469052013 1785 dbSNP
rs1193188804 1787 dbSNP
rs1393075333 1788 dbSNP
rs1451027677 1789 dbSNP
rs554650854 1789 dbSNP
rs776773766 1795 dbSNP
rs1036937185 1796 dbSNP
rs764512273 1802 dbSNP
rs1006413935 1808 dbSNP
rs1037863793 1816 dbSNP
rs1350163344 1822 dbSNP
rs887846565 1828 dbSNP
rs1050546139 1833 dbSNP
rs940330334 1844 dbSNP
rs907546624 1846 dbSNP
rs1276151777 1859 dbSNP
rs1339297739 1860 dbSNP
rs1199081066 1861 dbSNP
rs146761316 1862 dbSNP
rs1261793591 1864 dbSNP
rs1335506187 1877 dbSNP
rs1213304469 1880 dbSNP
rs760981929 1881 dbSNP
rs559711681 1894 dbSNP
rs1466134755 1895 dbSNP
rs1040908260 1896 dbSNP
rs1348655441 1900 dbSNP
rs1287820145 1903 dbSNP
rs1241489595 1906 dbSNP
rs1474375352 1907 dbSNP
rs1164872310 1912 dbSNP
rs949290113 1914 dbSNP
rs374859881 1916 dbSNP
rs1332504574 1917 dbSNP
rs1162362836 1919 dbSNP
rs1395210867 1925 dbSNP
rs913841816 1927 dbSNP
rs990587743 1928 dbSNP
rs958121099 1932 dbSNP
rs142206199 1936 dbSNP
rs979256601 1944 dbSNP
rs554476018 1948 dbSNP
rs988364281 1962 dbSNP
rs537612747 1979 dbSNP
rs1455591297 1983 dbSNP
rs1356192899 1987 dbSNP
rs1232739031 1988 dbSNP
rs186412013 1990 dbSNP
rs1331450170 2001 dbSNP
rs773935440 2002 dbSNP
rs1475935858 2011 dbSNP
rs1008926953 2013 dbSNP
rs1235361782 2017 dbSNP
rs148671773 2020 dbSNP
rs1258065395 2026 dbSNP
rs1474626630 2032 dbSNP
rs1185151733 2038 dbSNP
rs1413768465 2039 dbSNP
rs770581695 2040 dbSNP
rs1157582410 2041 dbSNP
rs1384707339 2041 dbSNP
rs996328131 2042 dbSNP
rs899333869 2050 dbSNP
rs969008618 2055 dbSNP
rs1414290517 2058 dbSNP
rs1262891859 2076 dbSNP
rs1024638006 2081 dbSNP
rs200349167 2090 dbSNP
rs1352365399 2091 dbSNP
rs962272189 2097 dbSNP
rs1268119931 2098 dbSNP
rs181396556 2100 dbSNP
rs748958940 2108 dbSNP
rs1037913795 2126 dbSNP
rs1358619244 2130 dbSNP
rs1281032374 2137 dbSNP
rs1282608239 2142 dbSNP
rs566569218 2145 dbSNP
rs1253371177 2149 dbSNP
rs1447608252 2151 dbSNP
rs1419082172 2153 dbSNP
rs1015205946 2154 dbSNP
rs1006773816 2186 dbSNP
rs1005033957 2188 dbSNP
rs1361693588 2189 dbSNP
rs886216456 2197 dbSNP
rs1326748582 2202 dbSNP
rs546971360 2215 dbSNP
rs1320050834 2220 dbSNP
rs1432718647 2221 dbSNP
rs1387802775 2224 dbSNP
rs1311556759 2225 dbSNP
rs887970466 2228 dbSNP
rs1136968 2236 dbSNP
rs1050904084 2246 dbSNP
rs1326554106 2250 dbSNP
rs1462529972 2268 dbSNP
rs1136967 2274 dbSNP
rs1046026694 2278 dbSNP
rs1162227374 2279 dbSNP
rs1475544066 2281 dbSNP
rs1235192238 2284 dbSNP
rs996226728 2293 dbSNP
rs1303846525 2300 dbSNP
rs1346818849 2302 dbSNP
rs1232029885 2312 dbSNP
rs949072323 2316 dbSNP
rs901971124 2317 dbSNP
rs1040351437 2331 dbSNP
rs936477990 2345 dbSNP
rs1452956540 2347 dbSNP
rs925104598 2353 dbSNP
rs1254058657 2359 dbSNP
rs1214900610 2370 dbSNP
rs777356850 2372 dbSNP
rs1454054125 2375 dbSNP
rs977984701 2378 dbSNP
rs1317411344 2380 dbSNP
rs967438075 2380 dbSNP
rs776993430 2391 dbSNP
rs1287834653 2407 dbSNP
rs1443411059 2412 dbSNP
rs1227891850 2414 dbSNP
rs1326781309 2447 dbSNP
rs1340319644 2448 dbSNP
rs1369994208 2451 dbSNP
rs190453638 2452 dbSNP
rs1297718261 2454 dbSNP
rs1225873531 2455 dbSNP
rs1307971769 2456 dbSNP
rs954701374 2472 dbSNP
rs1052379471 2481 dbSNP
rs771197021 2496 dbSNP
rs1213930963 2509 dbSNP
rs1272088380 2509 dbSNP
rs1304014376 2511 dbSNP
rs186042528 2523 dbSNP
rs936460688 2525 dbSNP
rs925148274 2541 dbSNP
rs996831186 2544 dbSNP
rs1193042045 2548 dbSNP
rs1371439664 2549 dbSNP
rs963698169 2553 dbSNP
rs1165999097 2557 dbSNP
rs773009293 2559 dbSNP
rs1005074016 2561 dbSNP
rs886163980 2574 dbSNP
rs879819576 2577 dbSNP
rs1381609063 2581 dbSNP
rs1293267316 2582 dbSNP
rs1398165030 2585 dbSNP
rs1013169569 2587 dbSNP
rs1166377121 2591 dbSNP
rs1212265501 2601 dbSNP
rs1332180044 2601 dbSNP
rs181554501 2601 dbSNP
rs969123085 2607 dbSNP
rs1448007000 2623 dbSNP
rs1205065740 2626 dbSNP
rs936576278 2628 dbSNP
rs917694804 2629 dbSNP
rs903793631 2637 dbSNP
rs1188708402 2649 dbSNP
rs1417472319 2650 dbSNP
rs1042591000 2656 dbSNP
rs755907112 2657 dbSNP
rs1452706041 2662 dbSNP
rs1287107499 2663 dbSNP
rs1194747469 2665 dbSNP
rs747942261 2667 dbSNP
rs987558463 2668 dbSNP
rs531099416 2670 dbSNP
rs1015567988 2676 dbSNP
rs1245550802 2677 dbSNP
rs1225148797 2680 dbSNP
rs1307183032 2682 dbSNP
rs1220913690 2692 dbSNP
rs1317913120 2693 dbSNP
rs1006478063 2695 dbSNP
rs933432675 2696 dbSNP
rs565457882 2705 dbSNP
rs974800596 2712 dbSNP
rs1212161325 2713 dbSNP
rs963945189 2717 dbSNP
rs1484692284 2731 dbSNP
rs1179180274 2732 dbSNP
rs1408961204 2733 dbSNP
rs1491589050 2735 dbSNP
rs1491101157 2736 dbSNP
rs371400030 2747 dbSNP
rs1484976100 2748 dbSNP
rs571141405 2748 dbSNP
rs1277001570 2750 dbSNP
rs545752311 2754 dbSNP
rs983994439 2766 dbSNP
rs996341605 2770 dbSNP
rs1223627650 2776 dbSNP
rs901920494 2781 dbSNP
rs1350449801 2792 dbSNP
rs1235671390 2794 dbSNP
rs1280168621 2800 dbSNP
rs1310574023 2817 dbSNP
rs1341134805 2825 dbSNP
rs1024640861 2827 dbSNP
rs1018998095 2828 dbSNP
rs1010167041 2830 dbSNP
rs1176953152 2831 dbSNP
rs891794755 2836 dbSNP
rs1454502030 2845 dbSNP
rs1172952745 2848 dbSNP
rs573573162 2850 dbSNP
rs1411193168 2853 dbSNP
rs553490216 2868 dbSNP
rs370410932 2869 dbSNP
rs540185214 2874 dbSNP
rs1256265730 2880 dbSNP
rs1351836451 2886 dbSNP
rs1303397470 2889 dbSNP
rs945152492 2894 dbSNP
rs574463546 2895 dbSNP
rs890964683 2899 dbSNP
rs1050950914 2903 dbSNP
rs1428725539 2904 dbSNP
rs1205230960 2909 dbSNP
rs554618106 2917 dbSNP
rs1306954288 2918 dbSNP
rs933380356 2926 dbSNP
rs947899079 2929 dbSNP
rs189159662 2931 dbSNP
rs1177241904 2937 dbSNP
rs1192741036 2938 dbSNP
rs975124125 2942 dbSNP
rs1476363355 2959 dbSNP
rs1416575688 2960 dbSNP
rs1423657462 2970 dbSNP
rs1418168240 2971 dbSNP
rs1407653663 2979 dbSNP
rs796367634 2980 dbSNP
rs575128796 2985 dbSNP
rs1394753319 2990 dbSNP
rs1462335656 2991 dbSNP
rs1325630567 2997 dbSNP
rs909419148 2998 dbSNP
rs1433541835 3000 dbSNP
rs558319901 3006 dbSNP
rs1180211256 3012 dbSNP
rs1216860756 3019 dbSNP
rs940311492 3033 dbSNP
rs983668423 3034 dbSNP
rs1213247564 3036 dbSNP
rs907545362 3038 dbSNP
rs1448446496 3041 dbSNP
rs573912168 3052 dbSNP
rs865854260 3057 dbSNP
rs1241432105 3058 dbSNP
rs952328851 3066 dbSNP
rs893993395 3071 dbSNP
rs1281392769 3075 dbSNP
rs1211954204 3077 dbSNP
rs1418188293 3078 dbSNP
rs1474691375 3079 dbSNP
rs1161056825 3081 dbSNP
rs1389033277 3086 dbSNP
rs1402746606 3086 dbSNP
rs951007481 3091 dbSNP
rs1345111527 3094 dbSNP
rs1310265442 3098 dbSNP
rs1029225009 3099 dbSNP
rs1398281130 3102 dbSNP
rs1314866016 3103 dbSNP
rs1356124692 3105 dbSNP
rs1184982641 3106 dbSNP
rs1212879396 3106 dbSNP
rs1224121895 3106 dbSNP
rs1232904543 3106 dbSNP
rs1257643446 3106 dbSNP
rs1282581121 3106 dbSNP
rs1283521473 3106 dbSNP
rs1306061278 3106 dbSNP
rs1352643002 3106 dbSNP
rs1365171521 3106 dbSNP
rs1380021494 3106 dbSNP
rs1439239571 3106 dbSNP
rs1454173930 3106 dbSNP
rs1471399653 3106 dbSNP
rs1485022481 3106 dbSNP
rs1487257152 3106 dbSNP
rs559201832 3106 dbSNP
rs57854212 3106 dbSNP
rs71114347 3106 dbSNP
rs1277787758 3107 dbSNP
rs1332517520 3107 dbSNP
rs1491198556 3108 dbSNP
rs1491369831 3109 dbSNP
rs1285919624 3110 dbSNP
rs56329106 3111 dbSNP
rs1355683671 3113 dbSNP
rs1304278973 3114 dbSNP
rs1450596472 3116 dbSNP
rs1278765845 3117 dbSNP
rs1357818996 3119 dbSNP
rs1175915286 3122 dbSNP
rs1458241727 3124 dbSNP
rs747122016 3125 dbSNP
rs1157027599 3139 dbSNP
rs1472336800 3145 dbSNP
rs1346601567 3148 dbSNP
rs966198418 3153 dbSNP
rs1198227918 3155 dbSNP
rs992314903 3157 dbSNP
rs1438068403 3158 dbSNP
rs56134232 3161 dbSNP
rs1180596946 3169 dbSNP
rs1237957933 3176 dbSNP
rs566715135 3177 dbSNP
rs1018944127 3182 dbSNP
rs368012699 3188 dbSNP
rs56196857 3195 dbSNP
rs780996053 3196 dbSNP
rs1236697671 3201 dbSNP
rs754842605 3209 dbSNP
rs1033012016 3215 dbSNP
rs1000905015 3216 dbSNP
rs1330857928 3228 dbSNP
rs1021080975 3236 dbSNP
rs185614651 3240 dbSNP
rs903758736 3251 dbSNP
rs1230502146 3252 dbSNP
rs1252585992 3253 dbSNP
rs1339395907 3254 dbSNP
rs891078265 3268 dbSNP
rs536616570 3271 dbSNP
rs1456767342 3284 dbSNP
rs1195854185 3286 dbSNP
rs567676841 3292 dbSNP
rs1334963905 3293 dbSNP
rs1045017916 3298 dbSNP
rs1314385223 3307 dbSNP
rs900554217 3309 dbSNP
rs765284927 3311 dbSNP
rs941984014 3313 dbSNP
rs909212071 3318 dbSNP
rs1047754033 3320 dbSNP
rs1462858412 3321 dbSNP
rs1326309711 3325 dbSNP
rs947845820 3327 dbSNP
rs115498843 3335 dbSNP
rs918191515 3337 dbSNP
rs992259324 3338 dbSNP
rs1326563453 3340 dbSNP
rs959575785 3349 dbSNP
rs1275951122 3352 dbSNP
rs1336460668 3386 dbSNP
rs1213872848 3387 dbSNP
rs1274236086 3392 dbSNP
rs1056194821 3403 dbSNP
rs926326258 3411 dbSNP
rs1208598115 3420 dbSNP
rs1302637946 3421 dbSNP
rs940446401 3426 dbSNP
rs1193001653 3429 dbSNP
rs1421823231 3430 dbSNP
rs6493153 3436 dbSNP
rs1165840528 3439 dbSNP
rs374266822 3440 dbSNP
rs968238546 3449 dbSNP
rs1020622249 3450 dbSNP
rs1009262201 3451 dbSNP
rs1456743093 3452 dbSNP
rs1398897250 3455 dbSNP
rs370942543 3459 dbSNP
rs1356767356 3462 dbSNP
rs1369155918 3462 dbSNP
rs1233533519 3470 dbSNP
rs1295060560 3477 dbSNP
rs1167113843 3481 dbSNP
rs1321559565 3484 dbSNP
rs1422294067 3498 dbSNP
rs754055892 3499 dbSNP
rs764267603 3506 dbSNP
rs1029597237 3507 dbSNP
rs1243068376 3507 dbSNP
rs997048463 3518 dbSNP
rs1559892 3522 dbSNP
rs1466127676 3532 dbSNP
rs1246086086 3543 dbSNP
rs1188991257 3547 dbSNP
rs1255731221 3548 dbSNP
rs1208064875 3560 dbSNP
rs1468500553 3562 dbSNP
rs1266711507 3565 dbSNP
rs1160986429 3571 dbSNP
rs1218838667 3574 dbSNP
rs551956314 3579 dbSNP
rs144995517 3581 dbSNP
rs768002150 3583 dbSNP
rs887887526 3589 dbSNP
rs1047700747 3594 dbSNP
rs1301968384 3606 dbSNP
rs559961625 3609 dbSNP
rs1309635791 3618 dbSNP
rs1019062144 3626 dbSNP
rs989424110 3629 dbSNP
rs1295361072 3638 dbSNP
rs1284486344 3639 dbSNP
rs956130235 3642 dbSNP
rs539867267 3647 dbSNP
rs1210866915 3658 dbSNP
rs1237165550 3668 dbSNP
rs180762892 3669 dbSNP
rs1179125736 3674 dbSNP
rs938303061 3682 dbSNP
rs926806598 3691 dbSNP
rs1176766860 3696 dbSNP
rs760064230 3697 dbSNP
rs1396813426 3701 dbSNP
rs775057853 3712 dbSNP
rs1169510430 3727 dbSNP
rs967806657 3770 dbSNP
rs1298335742 3773 dbSNP
rs1378186388 3788 dbSNP
rs1446502703 3793 dbSNP
rs1451057224 3793 dbSNP
rs1307765979 3798 dbSNP
rs1388115996 3803 dbSNP
rs970065582 3808 dbSNP
rs560703609 3813 dbSNP
rs1354715523 3833 dbSNP
rs955030637 3834 dbSNP
rs1206909537 3843 dbSNP
rs1012179640 3853 dbSNP
rs1457209475 3857 dbSNP
rs1196498143 3862 dbSNP
rs1269455928 3863 dbSNP
rs1478328293 3864 dbSNP
rs996771762 3865 dbSNP
rs896440762 3869 dbSNP
rs1170787091 3882 dbSNP
rs964339170 3885 dbSNP
rs1465477331 3886 dbSNP
rs543942034 3890 dbSNP
rs1397085009 3893 dbSNP
rs1005820982 3896 dbSNP
rs140849287 3898 dbSNP
rs374896139 3898 dbSNP
rs775651459 3898 dbSNP
rs1005148625 3900 dbSNP
rs886179056 3911 dbSNP
rs1216401630 3915 dbSNP
rs150021790 3916 dbSNP
rs896488032 3922 dbSNP
rs1196930951 3925 dbSNP
rs1274849037 3926 dbSNP
rs749746349 3933 dbSNP
rs938265759 3935 dbSNP
rs1332168914 3942 dbSNP
rs1304119913 3943 dbSNP
rs558336349 3945 dbSNP
rs1385124593 3953 dbSNP
rs905468443 3958 dbSNP
rs1476651957 3962 dbSNP
rs921608062 3968 dbSNP
rs1038707817 3970 dbSNP
rs1166563212 3975 dbSNP
rs1308812319 3982 dbSNP
rs944956857 3989 dbSNP
rs373047932 3996 dbSNP
rs1348620386 4005 dbSNP
rs1167721619 4009 dbSNP
rs912169739 4011 dbSNP
rs76255178 4026 dbSNP
rs139307794 4030 dbSNP
rs147472374 4031 dbSNP
rs1295291878 4032 dbSNP
rs143014862 4034 dbSNP
rs1227497833 4036 dbSNP
rs748790246 4037 dbSNP
rs1251929761 4040 dbSNP
rs1183817834 4042 dbSNP
rs933765706 4043 dbSNP
rs1217193613 4046 dbSNP
rs1261836921 4053 dbSNP
rs1486987163 4057 dbSNP
rs772898834 4059 dbSNP
rs1473355453 4069 dbSNP
rs1163021938 4071 dbSNP
rs1412018159 4082 dbSNP
rs1422094943 4086 dbSNP
rs140682920 4087 dbSNP
rs1359997906 4088 dbSNP
rs565543928 4091 dbSNP
rs1341269986 4095 dbSNP
rs1346205186 4096 dbSNP
rs189278247 4100 dbSNP
rs184820155 4104 dbSNP
rs1035379743 4124 dbSNP
rs571728604 4125 dbSNP
rs1289070982 4127 dbSNP
rs1004694143 4133 dbSNP
rs886273106 4148 dbSNP
rs1048766800 4150 dbSNP
rs994535678 4158 dbSNP
rs900299113 4171 dbSNP
rs1278958737 4175 dbSNP
rs1441512703 4176 dbSNP
rs983940777 4179 dbSNP
rs951220517 4180 dbSNP
rs1441869046 4181 dbSNP
rs1025472669 4193 dbSNP
rs576482078 4195 dbSNP
rs993535840 4213 dbSNP
rs944403850 4215 dbSNP
rs912117284 4218 dbSNP
rs1417991586 4227 dbSNP
rs1307711805 4229 dbSNP
rs896605529 4233 dbSNP
rs1053799244 4235 dbSNP
rs1153830 4237 dbSNP
rs926122531 4249 dbSNP
rs1337368115 4255 dbSNP
rs1404118317 4257 dbSNP
rs1170689209 4260 dbSNP
rs978987047 4266 dbSNP
rs1308502340 4267 dbSNP
rs528656270 4268 dbSNP
rs905416946 4269 dbSNP
rs970129386 4292 dbSNP
rs11554174 4301 dbSNP
rs916023409 4305 dbSNP
rs1160728091 4343 dbSNP
rs992817530 4344 dbSNP
rs960043331 4351 dbSNP
rs768496333 4352 dbSNP
rs1459425152 4358 dbSNP
rs1199638508 4363 dbSNP
rs1237901191 4364 dbSNP
rs113261769 4381 dbSNP
rs1438418082 4381 dbSNP
rs60951957 4381 dbSNP
rs200122678 4382 dbSNP
rs1187853801 4386 dbSNP
rs1378287506 4390 dbSNP
rs892632888 4402 dbSNP
rs983780012 4403 dbSNP
rs1052635749 4405 dbSNP
rs950695516 4413 dbSNP
rs1199179094 4417 dbSNP
rs192787221 4424 dbSNP
rs1330458113 4426 dbSNP
rs1397804755 4428 dbSNP
rs1388451939 4432 dbSNP
rs562993816 4439 dbSNP
rs922369484 4440 dbSNP
rs1271617811 4447 dbSNP
rs1269382753 4454 dbSNP
rs1318180931 4462 dbSNP
rs994653125 4473 dbSNP
rs1217589347 4474 dbSNP
rs1257827011 4478 dbSNP
rs1456675982 4489 dbSNP
rs900248590 4503 dbSNP
rs975081798 4508 dbSNP
rs1268661186 4512 dbSNP
rs1451147782 4513 dbSNP
rs549682996 4514 dbSNP
rs1008494056 4517 dbSNP
rs890121826 4518 dbSNP
rs909762046 4520 dbSNP
rs1327211161 4524 dbSNP
rs1459241142 4532 dbSNP
rs1279142351 4543 dbSNP
rs1053340860 4552 dbSNP
rs984442730 4560 dbSNP
rs934900391 4566 dbSNP
rs1399027145 4578 dbSNP
rs1275897921 4584 dbSNP
rs1306187720 4600 dbSNP
rs951334325 4607 dbSNP
rs904814802 4609 dbSNP
rs1395302230 4611 dbSNP
rs1043230810 4612 dbSNP
rs1389263354 4615 dbSNP
rs948896080 4616 dbSNP
rs915971037 4617 dbSNP
rs992914032 4620 dbSNP
rs1356288881 4621 dbSNP
rs1208536770 4627 dbSNP
rs1322519603 4654 dbSNP
rs1265433730 4656 dbSNP
rs918407384 4658 dbSNP
rs1193293165 4660 dbSNP
rs1261304640 4665 dbSNP
rs752331895 4678 dbSNP
rs1165242896 4679 dbSNP
rs1410615397 4688 dbSNP
rs938629159 4689 dbSNP
rs187510707 4695 dbSNP
rs908528348 4697 dbSNP
rs1473578597 4702 dbSNP
rs1398843237 4708 dbSNP
rs1296003261 4719 dbSNP
rs982840283 4730 dbSNP
rs1035529519 4731 dbSNP
rs560983904 4746 dbSNP
rs746942115 4749 dbSNP
rs8034420 4753 dbSNP
rs973181516 4755 dbSNP
rs964532277 4757 dbSNP
rs1017269446 4758 dbSNP
rs1022332873 4765 dbSNP
rs1215950769 4766 dbSNP
rs1011153091 4778 dbSNP
rs1463557564 4781 dbSNP
rs572459605 4783 dbSNP
rs757333890 4785 dbSNP
rs892749016 4788 dbSNP
rs890245433 4802 dbSNP
rs1031752246 4804 dbSNP
rs998557655 4813 dbSNP
rs1421816219 4817 dbSNP
rs1358726736 4825 dbSNP
rs904763096 4826 dbSNP
rs1380804944 4827 dbSNP
rs28404754 4830 dbSNP
rs1282696116 4831 dbSNP
rs371644720 4838 dbSNP
rs998373161 4840 dbSNP
rs753807846 4855 dbSNP
rs552892585 4858 dbSNP
rs1301841501 4877 dbSNP
rs1402021016 4879 dbSNP
rs900890791 4886 dbSNP
rs534478436 4887 dbSNP
rs1378271464 4888 dbSNP
rs1240004334 4889 dbSNP
rs1304960575 4894 dbSNP
rs1432828933 4901 dbSNP
rs1153831 4913 dbSNP
rs894653469 4926 dbSNP
rs909532234 4934 dbSNP
rs1459844041 4936 dbSNP
rs564606455 4950 dbSNP
rs1057353653 4952 dbSNP
rs1048088666 4971 dbSNP
rs1176628423 4980 dbSNP
rs1426683338 4983 dbSNP
rs938760434 4984 dbSNP
rs544829018 4991 dbSNP
rs918523793 5005 dbSNP
rs1375544211 5012 dbSNP
rs545857467 5018 dbSNP
rs1391189583 5019 dbSNP
rs983175721 5025 dbSNP
rs1401393306 5044 dbSNP
rs558410602 5050 dbSNP
rs373026102 5052 dbSNP
rs928029641 5054 dbSNP
rs920488299 5076 dbSNP
rs1369900319 5081 dbSNP
rs973295491 5090 dbSNP
rs78382605 5098 dbSNP
rs369371340 5099 dbSNP
rs969531922 5111 dbSNP
rs1321696213 5116 dbSNP
rs552876572 5121 dbSNP
rs114062426 5122 dbSNP
rs1242109666 5125 dbSNP
rs1457109120 5128 dbSNP
rs987305547 5137 dbSNP
rs1453443154 5148 dbSNP
rs954594934 5152 dbSNP
rs1470852364 5161 dbSNP
rs1422389898 5162 dbSNP
rs1478599381 5164 dbSNP
rs1222058340 5170 dbSNP
rs1031450570 5174 dbSNP
rs752983818 5176 dbSNP
rs956918322 5199 dbSNP
rs147332709 5213 dbSNP
rs968434574 5239 dbSNP
rs1021850052 5243 dbSNP
rs901335919 5248 dbSNP
rs555724664 5256 dbSNP
rs540315110 5258 dbSNP
rs1225989166 5268 dbSNP
rs1013164006 5270 dbSNP
rs1343647466 5271 dbSNP
rs1039907649 5272 dbSNP
rs894767641 5282 dbSNP
rs1275414870 5294 dbSNP
rs1007038902 5299 dbSNP
rs1317144548 5300 dbSNP
rs888227676 5303 dbSNP
rs1057300394 5310 dbSNP
rs1048028280 5311 dbSNP
rs1328880384 5318 dbSNP
rs1003071628 5320 dbSNP
rs887161776 5321 dbSNP
rs1430012695 5322 dbSNP
rs1194012776 5323 dbSNP
rs1220691882 5323 dbSNP
rs1266164309 5323 dbSNP
rs139116750 5323 dbSNP
rs766957144 5323 dbSNP
rs878955472 5323 dbSNP
rs1406467657 5326 dbSNP
rs929658460 5326 dbSNP
rs1371485130 5328 dbSNP
rs1363853337 5337 dbSNP
rs918471417 5341 dbSNP
rs1170871508 5367 dbSNP
rs1428279624 5370 dbSNP
rs1419390004 5371 dbSNP
rs1285767565 5374 dbSNP
rs1379548784 5375 dbSNP
rs557399875 5377 dbSNP
rs931267242 5383 dbSNP
rs938649472 5395 dbSNP
rs1355273856 5407 dbSNP
rs1216675105 5418 dbSNP
rs1284625381 5421 dbSNP
rs1444953951 5426 dbSNP
rs1245069422 5428 dbSNP
rs1189109333 5455 dbSNP
rs927109077 5488 dbSNP
rs1473323703 5495 dbSNP
rs1183586418 5496 dbSNP
rs1383895267 5499 dbSNP
rs1441680983 5499 dbSNP
rs1159356031 5508 dbSNP
rs919935943 5512 dbSNP
rs979986329 5514 dbSNP
rs1359592527 5519 dbSNP
rs1446971686 5520 dbSNP
rs1202732610 5521 dbSNP
rs1039713311 5523 dbSNP
rs943288911 5534 dbSNP
rs1240735647 5539 dbSNP
rs910494125 5543 dbSNP
rs75539303 5548 dbSNP
rs767983894 5549 dbSNP
rs915346845 5549 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agauuguggugucACACCAAAc 5'
                       |||||||| 
Target 5' -------------UGUGGUUUu 3'
 		1 - 9
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000261867.4 | 3UTR | UGUGGUUUUGUUUUUGUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer -0.635 4.3e-4 -0.521 4.5e-3 24 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.551 2.2e-3 0.587 1.0e-3 25 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.357 6.1e-2 0.044 4.3e-1 20 Click to see details
GSE19350 CNS germ cell tumors 0.454 6.9e-2 0.573 2.6e-2 12 Click to see details
GSE32688 Pancreatic cancer 0.177 1.7e-1 0.171 1.7e-1 32 Click to see details
GSE28260 Renal cortex and medulla -0.095 3.8e-1 -0.056 4.3e-1 13 Click to see details
GSE21687 Ependynoma primary tumors -0.029 4.1e-1 -0.087 2.5e-1 64 Click to see details
GSE38226 Liver fibrosis -0.038 4.4e-1 0.099 3.3e-1 21 Click to see details
GSE17498 Multiple myeloma -0.014 4.7e-1 0.115 2.4e-1 40 Click to see details
GSE26953 Aortic valvular endothelial cells 0.012 4.8e-1 -0.003 4.9e-1 24 Click to see details
GSE26953 Aortic valvular endothelial cells 0.012 4.8e-1 -0.003 4.9e-1 24 Click to see details
GSE26953 Aortic valvular endothelial cells 0.012 4.8e-1 -0.003 4.9e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
STAD -0.396 0.04 -0.412 0.03 21 Click to see details
PRAD -0.206 0.08 -0.156 0.15 46 Click to see details
BRCA -0.14 0.19 -0.268 0.04 42 Click to see details
LIHC -0.167 0.19 -0.107 0.29 30 Click to see details
HNSC 0.18 0.24 0.397 0.05 18 Click to see details
PAAD 0.508 0.25 0.400 0.3 4 Click to see details
LUAD 0.473 0.26 0.400 0.3 4 Click to see details
KICH 0.156 0.29 0.307 0.13 15 Click to see details
CHOL 0.262 0.31 0.429 0.2 6 Click to see details
UCEC 0.111 0.34 0.188 0.24 16 Click to see details
KIRP 0.076 0.37 0.164 0.24 21 Click to see details
LUSC 0.053 0.39 0.196 0.15 30 Click to see details
BLCA -0.209 0.4 -0.200 0.4 4 Click to see details
THCA 0.036 0.41 0.087 0.28 45 Click to see details
KIRC -0.022 0.44 -0.001 0.5 43 Click to see details
ESCA -0.018 0.48 0.115 0.38 10 Click to see details
ESCA -0.018 0.48 0.115 0.38 10 Click to see details
ESCA -0.018 0.48 0.115 0.38 10 Click to see details
ESCA -0.018 0.48 0.115 0.38 10 Click to see details
95 hsa-miR-497-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT092955 CYP2U1 cytochrome P450 family 2 subfamily U member 1 2 4
MIRT124568 PRRC2B proline rich coiled-coil 2B 2 2
MIRT125196 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 4
MIRT147296 KPNA2 karyopherin subunit alpha 2 2 8
MIRT163999 KIAA1109 KIAA1109 2 4
MIRT252495 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT357969 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT443007 TRIOBP TRIO and F-actin binding protein 2 2
MIRT443524 NETO1 neuropilin and tolloid like 1 2 2
MIRT443573 EVX2 even-skipped homeobox 2 2 2
MIRT443656 BACH1 BTB domain and CNC homolog 1 2 2
MIRT460670 KRT10 keratin 10 2 8
MIRT464761 UBE2N ubiquitin conjugating enzyme E2 N 2 2
MIRT465032 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT465040 TTC39C tetratricopeptide repeat domain 39C 2 2
MIRT468667 SEC62 SEC62 homolog, preprotein translocation factor 2 2
MIRT473694 MAPK8 mitogen-activated protein kinase 8 2 4
MIRT477618 EFNA3 ephrin A3 2 2
MIRT480506 C11orf57 chromosome 11 open reading frame 57 2 2
MIRT480592 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT486915 ZNF398 zinc finger protein 398 2 6
MIRT487770 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 16
MIRT493265 MDFIC MyoD family inhibitor domain containing 2 2
MIRT495271 SLC1A2 solute carrier family 1 member 2 2 4
MIRT495309 CHST12 carbohydrate sulfotransferase 12 2 2
MIRT496681 DPP6 dipeptidyl peptidase like 6 2 4
MIRT496891 FOXP1 forkhead box P1 2 2
MIRT497330 IRF4 interferon regulatory factor 4 2 2
MIRT498272 KIAA1644 KIAA1644 2 2
MIRT498634 CHD4 chromodomain helicase DNA binding protein 4 2 10
MIRT500581 USP53 ubiquitin specific peptidase 53 2 2
MIRT500751 TMPPE transmembrane protein with metallophosphoesterase domain 2 6
MIRT509668 ZNF354B zinc finger protein 354B 2 10
MIRT510919 PSMA2 proteasome subunit alpha 2 2 4
MIRT519118 CEP76 centrosomal protein 76 2 2
MIRT526193 ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) 2 2
MIRT526746 HLA-DOB major histocompatibility complex, class II, DO beta 2 2
MIRT527270 FBLN2 fibulin 2 2 2
MIRT528198 PLEKHM2 pleckstrin homology and RUN domain containing M2 2 2
MIRT528330 TBC1D22B TBC1 domain family member 22B 2 2
MIRT530346 GABRB3 gamma-aminobutyric acid type A receptor beta3 subunit 2 2
MIRT533627 TMX3 thioredoxin related transmembrane protein 3 2 2
MIRT533738 TMEM200C transmembrane protein 200C 2 2
MIRT533779 TMEM133 transmembrane protein 133 2 2
MIRT534317 SKIDA1 SKI/DACH domain containing 1 2 2
MIRT538438 COG5 component of oligomeric golgi complex 5 2 2
MIRT539156 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2 2
MIRT539474 ADARB2 adenosine deaminase, RNA specific B2 (inactive) 2 2
MIRT539620 SHISA9 shisa family member 9 2 2
MIRT539650 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT540346 OPHN1 oligophrenin 1 2 2
MIRT540412 PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 2 2
MIRT541200 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 2
MIRT541395 CDC27 cell division cycle 27 2 2
MIRT546443 SNX5 sorting nexin 5 2 2
MIRT547369 MSI2 musashi RNA binding protein 2 2 2
MIRT553288 TSPAN3 tetraspanin 3 2 2
MIRT554402 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT557822 FOXN2 forkhead box N2 2 2
MIRT568530 ANP32E acidic nuclear phosphoprotein 32 family member E 2 2
MIRT569508 THYN1 thymocyte nuclear protein 1 2 2
MIRT570707 FAM69A family with sequence similarity 69 member A 2 2
MIRT608376 PIWIL2 piwi like RNA-mediated gene silencing 2 2 2
MIRT608483 NKTR natural killer cell triggering receptor 2 6
MIRT613533 TRA2B transformer 2 beta homolog 2 2
MIRT616601 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT618166 DUSP18 dual specificity phosphatase 18 2 2
MIRT632059 CEP135 centrosomal protein 135 2 2
MIRT647379 ZDHHC23 zinc finger DHHC-type containing 23 2 2
MIRT648366 POTED POTE ankyrin domain family member D 2 2
MIRT651075 ZNF518B zinc finger protein 518B 2 4
MIRT653618 SLC30A4 solute carrier family 30 member 4 2 2
MIRT653636 SLC30A1 solute carrier family 30 member 1 2 2
MIRT654895 POU2F1 POU class 2 homeobox 1 2 2
MIRT656232 MFSD6 major facilitator superfamily domain containing 6 2 2
MIRT659880 CAPRIN1 cell cycle associated protein 1 2 2
MIRT660526 ARL4C ADP ribosylation factor like GTPase 4C 2 2
MIRT666286 SLC30A3 solute carrier family 30 member 3 2 2
MIRT686808 SNX2 sorting nexin 2 2 4
MIRT695302 TK1 thymidine kinase 1 2 2
MIRT699737 SERINC3 serine incorporator 3 2 2
MIRT700794 PIAS2 protein inhibitor of activated STAT 2 2 2
MIRT712270 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT712617 KNSTRN kinetochore localized astrin/SPAG5 binding protein 2 2
MIRT714264 RPL10A ribosomal protein L10a 2 2
MIRT715072 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT715386 TADA3 transcriptional adaptor 3 2 2
MIRT716397 NPAS1 neuronal PAS domain protein 1 2 2
MIRT725328 NFASC neurofascin 2 2
MIRT725503 GANAB glucosidase II alpha subunit 2 2
MIRT732913 IRAK2 interleukin 1 receptor associated kinase 2 3 0
MIRT734890 SMAD3 SMAD family member 3 3 0
MIRT737328 LINC02476 long intergenic non-protein coding RNA 2476 3 0
MIRT737544 MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 4 0
MIRT755545 PAK1 p21 (RAC1) activated kinase 1 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-497 Bufalin NULL 9547215 Quantitative real-time PCR colorectal cancer HCT116 cells 24375248 2014 up-regulated
miR-497 Diethylstilbestrol approved 448537 Microarray mammosphere-derived epithelial cells (MDEC) 19549897 2009 up-regulated
miR-497 Ethanol NULL 702 Quantitative real-time PCR CIE10 22141737 2012 up-regulated
miR-497 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 up-regulated
miR-497 Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-497 Tamoxifen 2733525 NSC180973 approved sensitive Low Breast Cancer cell line (MCF-7, T47D)
hsa-mir-497 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-497 Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-497 Androstenedione+Letrozole sensitive cell line (MCF-7)
hsa-mir-497 Tamoxifen 2733525 NSC180973 approved sensitive cell line (MCF7)
hsa-mir-497 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-497-3p Mitoxantrone 4212 NSC279836 approved sensitive High Breast Cancer cell line (BT-20, BT-474, BT-549, CAMA-1, HCC1143, HCC1395, HCC1569, HCC1806, HCC-1937, HCC1954, HCC202, HCC38, HCC70, Hs578T, MCF-7, MDA-MB-175VII, MDA-MB-231, MDA-MB-361, MDA-MB-415, MDA-MB-436, MDA-MB-468, SKBR3, T47D, UACC812, EVSA-T, MPE-600 , SK-BR-
hsa-miR-497-3p Docetaxel 148124 NSC628503 approved resistant High Breast Cancer cell line (MDA-MB-231, MCF-7)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549, PC-9)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved resistant Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-497-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-497-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved resistant tissue
hsa-miR-497-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-497-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)

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