pre-miRNA Information
pre-miRNA hsa-mir-4680   
Genomic Coordinates chr10: 110898090 - 110898155
Description Homo sapiens miR-4680 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4680-5p
Sequence 5| AGAACUCUUGCAGUCUUAGAUGU |27
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1274530692 2 dbSNP
rs780271274 5 dbSNP
rs1461423681 7 dbSNP
rs749729920 8 dbSNP
rs1252920446 10 dbSNP
rs201739274 11 dbSNP
rs774971106 19 dbSNP
rs748132091 22 dbSNP
rs773643180 22 dbSNP
rs1235425484 23 dbSNP
Putative Targets

Gene Information
Gene Symbol RAB1A   
Synonyms RAB1, YPT1
Description RAB1A, member RAS oncogene family
Transcript NM_004161   
Other Transcripts NM_015543   
Expression
Putative miRNA Targets on RAB1A
3'UTR of RAB1A
(miRNA target sites are highlighted)
>RAB1A|NM_004161|3'UTR
   1 AATTTGCCTCCATCCTTTTCTCACAGCAATGAATTTGCAATCTGAACCCAAGTGAAAAAACAAAATTGCCTGAATTGTAC
  81 TGTATGTAGCTGCACTACAACAGATTCTTACCGTCTCCACAAAGGTCAGAGATTGTAAATGGTCAATACTGACTTTTTTT
 161 TTATTCCCTTGACTCAAGACAGCTAACTTCATTTTCAGAACTGTTTTAAACCTTTGTGTGCTGGTTTATAAAATAATGTG
 241 TGTAATCCTTGTTGCTTTCCTGATACCAGACTGTTTCCCGTGGTTGGTTAGAATATATTTTGTTTTGATGTTTATATTGG
 321 CATGTTTAGATGTCAGGTTTAGTCTTCTGAAGATGAAGTTCAGCCATTTTGTATCAAACAGCACAAGCAGTGTCTGTCAC
 401 TTTCCATGCATAAAGTTTAGTGAGATGTTATATGTAAGATCTGATTTGCTAGTTCTTCCTTGTAGAGTTATAAATGGAAA
 481 GATTACACTATCTGATTAATAGTTTCTTCATACTCTGCATATAATTTGTGGCTGCAGAATATTGTAATTTGTTGCACACT
 561 ATGTAACAAAACAACTGAAGATATGTTTAATAAATATTGTACTTATTGGAAGTAATATCAAACTGTATGGTGATAAGTAT
 641 TGTTTTGATTCTTATGGTTAAAGGGAAATAGAGCCTTGCATTATATTCAACACAGCCATTTGTGTGTGCACAATGCAAAC
 721 TAAGGTATTCTAGACCTATCTTAGAGCAGCATCCAGTATTTGCTTTCTAGATAATATGCCCAATAACATGACCTAGAGGG
 801 GCTTCTGTGCTGTGTAGGGATTTAACCAACTTCAGTGGTTCAGGGAGCTCAAACTATATGTAAAACAAGTTTAGAATGTA
 881 TGCTATCTAGCCCGTTATCTCTGATCCTTCTCTAAAACCATTTGAAATAGCTTCATTGATCAACATTTCATAAATGCATC
 961 TGTGGTAGAGGTAGAAAGCAGCACCTTTCCTAATTGGCAAATGATCAGACTAATGTGTGCTAATGTTTTTCTTCCATGCT
1041 TTCAGTCAGATTCAACTATTTTATCCTCCACAGTTGCTTAACTTGGTGTTGGAGGAGGGTTTAAGCATTAAGATAGGAAG
1121 CAGGAAATTTGATTGCTCTAAATTTAGAAATTATATCCCTAAAAATTAAAACATGAATACTGGGTGGTAATGATAATTGA
1201 GGCAAATGTATTTATTTTGGTGACATTTTGCATATATGAAGATTTTCTGAAATAGGACCTTCAAGATCCTAGGGGGTTTT
1281 GTTTGGTTTTTAATTGTGAGGAATAAAAAATCTTCTGCCCACACTGGCATTTTAAGGTGACTGAGGTCAAACGTTGTTTC
1361 CTTAGGTTGAAATAGCAGCCAAAACATTCTTCACGCAGGGGCTTGGGATATGGCTGCTGGCAACACATTTTGTTGTGGGC
1441 TCCTTAATTTAATGATAAAATTTAAGCTAAACACAAGCCAAAAATGAATAGGTTTTTTTAATTTTTATTTTTCACTAAAC
1521 AGGCAATTGAAATACATGGTACAAAAATAAGTGGTAAGATAATTGTAAAATGAAATGGACAGAATATTCAATTTTCCATC
1601 TATGAAAATTTCACAATAAAAATCATAGTTTACTTTGTAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' uguaGAUUCUGACG----UUCUCAAga 5'
              |||:  || |     ||||||  
Target 5' tttgCTAGTTCTTCCTTGTAGAGTTat 3'
445 - 471 125.00 -7.80
2
miRNA  3' ugUAGAUUCUGACGU--UCUCAAGa 5'
            | :|:: ::|| |  ||:|||: 
Target 5' taACTTGGTGTTGGAGGAGGGTTTa 3'
1079 - 1103 119.00 -10.20
3
miRNA  3' ugUAGAUU--CUGACGUUC-UCAAGa 5'
            ||:|||   ||| | || :|||| 
Target 5' ggATTTAACCAACTTC-AGTGGTTCa 3'
818 - 842 114.00 -8.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20074432 11 COSMIC
COSN14003094 12 COSMIC
COSN26547594 16 COSMIC
COSN30168076 131 COSMIC
COSN31518915 153 COSMIC
COSN20921966 262 COSMIC
COSN26669297 279 COSMIC
COSN6190397 680 COSMIC
COSN5508723 690 COSMIC
COSN31528285 763 COSMIC
COSN31589442 845 COSMIC
COSN28202089 1236 COSMIC
COSN31518100 1501 COSMIC
COSN31568100 1550 COSMIC
COSN26577326 1614 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1227489017 7 dbSNP
rs751426005 10 dbSNP
rs1369863651 15 dbSNP
rs763943567 18 dbSNP
rs1289725745 20 dbSNP
rs1405445822 24 dbSNP
rs759806008 25 dbSNP
rs755397579 29 dbSNP
rs1402114237 33 dbSNP
rs750059070 35 dbSNP
rs566920211 40 dbSNP
rs1159522600 43 dbSNP
rs369450925 47 dbSNP
rs1410209424 49 dbSNP
rs1358562591 52 dbSNP
rs947790261 61 dbSNP
rs1272606404 62 dbSNP
rs1465549585 75 dbSNP
rs1013327225 76 dbSNP
rs1479070092 77 dbSNP
rs917630989 82 dbSNP
rs764977210 95 dbSNP
rs1369056179 96 dbSNP
rs886880838 99 dbSNP
rs761186202 100 dbSNP
rs1443384907 107 dbSNP
rs938818436 109 dbSNP
rs1205477937 111 dbSNP
rs924919188 112 dbSNP
rs898710762 113 dbSNP
rs1313872835 117 dbSNP
rs1344645645 126 dbSNP
rs760395230 129 dbSNP
rs150872549 135 dbSNP
rs1329882642 140 dbSNP
rs1315966384 141 dbSNP
rs530260936 146 dbSNP
rs1021575731 148 dbSNP
rs1051076490 150 dbSNP
rs946118671 155 dbSNP
rs975350684 159 dbSNP
rs1256569228 162 dbSNP
rs1185657876 163 dbSNP
rs1277519006 163 dbSNP
rs964100076 166 dbSNP
rs1416552887 167 dbSNP
rs913359801 175 dbSNP
rs1361768091 187 dbSNP
rs1452584251 189 dbSNP
rs1342046796 192 dbSNP
rs1303837131 202 dbSNP
rs1331725714 213 dbSNP
rs1404755859 214 dbSNP
rs1395079391 217 dbSNP
rs987928104 221 dbSNP
rs1474346224 223 dbSNP
rs561046036 226 dbSNP
rs1020093668 228 dbSNP
rs1312746582 229 dbSNP
rs1008089773 235 dbSNP
rs886922704 244 dbSNP
rs957867128 247 dbSNP
rs925166736 248 dbSNP
rs1316604668 252 dbSNP
rs544342002 260 dbSNP
rs1256400360 263 dbSNP
rs1346801183 276 dbSNP
rs1208655759 277 dbSNP
rs760664390 279 dbSNP
rs995821367 290 dbSNP
rs1183782815 295 dbSNP
rs1024625141 297 dbSNP
rs1172162757 308 dbSNP
rs1463625462 310 dbSNP
rs898378884 313 dbSNP
rs1422058560 314 dbSNP
rs1170599244 315 dbSNP
rs1433177387 317 dbSNP
rs75669866 318 dbSNP
rs1473297326 327 dbSNP
rs15048 328 dbSNP
rs1013296486 346 dbSNP
rs1371779458 352 dbSNP
rs538067960 359 dbSNP
rs775634911 361 dbSNP
rs1185950580 373 dbSNP
rs1372648623 375 dbSNP
rs569183939 379 dbSNP
rs1442025436 381 dbSNP
rs1044752935 387 dbSNP
rs947676104 390 dbSNP
rs1303601874 391 dbSNP
rs771978220 400 dbSNP
rs1332610590 404 dbSNP
rs191115996 410 dbSNP
rs1056605960 418 dbSNP
rs1456527200 420 dbSNP
rs1257276206 430 dbSNP
rs1342838152 431 dbSNP
rs1228837049 439 dbSNP
rs1249140679 459 dbSNP
rs1358461354 461 dbSNP
rs898682013 468 dbSNP
rs770810440 481 dbSNP
rs1040332039 486 dbSNP
rs1452172912 487 dbSNP
rs938888808 488 dbSNP
rs1391138114 492 dbSNP
rs1377115715 496 dbSNP
rs1332982827 498 dbSNP
rs1354024320 498 dbSNP
rs924773827 500 dbSNP
rs1295355911 502 dbSNP
rs891397304 502 dbSNP
rs1051046187 505 dbSNP
rs1406454102 531 dbSNP
rs1302457420 532 dbSNP
rs1416638936 535 dbSNP
rs1216274671 542 dbSNP
rs1293275010 544 dbSNP
rs946087291 559 dbSNP
rs1221738594 560 dbSNP
rs1266676224 561 dbSNP
rs1212637935 563 dbSNP
rs1466890055 563 dbSNP
rs913287450 567 dbSNP
rs1472688674 568 dbSNP
rs1451657289 572 dbSNP
rs1185289779 575 dbSNP
rs1381109234 576 dbSNP
rs745699162 580 dbSNP
rs1054487105 585 dbSNP
rs977738315 587 dbSNP
rs947647748 597 dbSNP
rs1392332537 599 dbSNP
rs774675538 606 dbSNP
rs1321404987 609 dbSNP
rs1389111662 611 dbSNP
rs1432720764 613 dbSNP
rs1286887707 615 dbSNP
rs1361248966 618 dbSNP
rs565303305 621 dbSNP
rs1437847353 625 dbSNP
rs1228786888 627 dbSNP
rs925125479 630 dbSNP
rs975404401 633 dbSNP
rs1232315167 643 dbSNP
rs969329904 648 dbSNP
rs981034396 648 dbSNP
rs1214162398 651 dbSNP
rs1241866934 652 dbSNP
rs1483885463 654 dbSNP
rs771209043 655 dbSNP
rs1453225785 663 dbSNP
rs544940077 668 dbSNP
rs758933604 671 dbSNP
rs1354149603 674 dbSNP
rs987287004 680 dbSNP
rs951279994 690 dbSNP
rs1310916322 696 dbSNP
rs1025907313 700 dbSNP
rs1316012628 702 dbSNP
rs995297197 708 dbSNP
rs1237489384 711 dbSNP
rs1344346808 722 dbSNP
rs185120684 728 dbSNP
rs1448699368 736 dbSNP
rs898431234 738 dbSNP
rs1023527355 740 dbSNP
rs1375776157 741 dbSNP
rs991788234 744 dbSNP
rs1274890292 747 dbSNP
rs114374370 750 dbSNP
rs1438046979 755 dbSNP
rs7600616 763 dbSNP
rs995269200 769 dbSNP
rs1221681409 780 dbSNP
rs1284042296 783 dbSNP
rs1322182218 793 dbSNP
rs573919976 795 dbSNP
rs777915934 796 dbSNP
rs896137078 814 dbSNP
rs1213654476 821 dbSNP
rs962806145 822 dbSNP
rs762483968 823 dbSNP
rs142285918 825 dbSNP
rs1254033433 827 dbSNP
rs1417317708 834 dbSNP
rs891372138 835 dbSNP
rs182541222 836 dbSNP
rs571130525 838 dbSNP
rs1406994907 848 dbSNP
rs1160889804 850 dbSNP
rs1175275008 855 dbSNP
rs756216859 856 dbSNP
rs947535161 858 dbSNP
rs1433999450 860 dbSNP
rs1308151258 865 dbSNP
rs1336970835 871 dbSNP
rs557753719 876 dbSNP
rs1407585011 880 dbSNP
rs534357331 884 dbSNP
rs748644728 885 dbSNP
rs1244838347 886 dbSNP
rs912545635 888 dbSNP
rs936079194 891 dbSNP
rs567133381 892 dbSNP
rs374680749 893 dbSNP
rs1347843754 894 dbSNP
rs781703250 897 dbSNP
rs986784154 898 dbSNP
rs1275233776 899 dbSNP
rs1488609328 901 dbSNP
rs755301364 904 dbSNP
rs1436095343 905 dbSNP
rs1181366352 907 dbSNP
rs1247579050 918 dbSNP
rs1287887383 929 dbSNP
rs546937502 933 dbSNP
rs1195317457 946 dbSNP
rs11884205 956 dbSNP
rs973914819 957 dbSNP
rs778379087 958 dbSNP
rs1278924419 964 dbSNP
rs1398018933 968 dbSNP
rs1407785197 969 dbSNP
rs879147058 978 dbSNP
rs1220415583 983 dbSNP
rs1350162158 986 dbSNP
rs1364882142 989 dbSNP
rs917799397 992 dbSNP
rs992096131 994 dbSNP
rs1370654198 1000 dbSNP
rs1229805732 1002 dbSNP
rs1273528205 1006 dbSNP
rs1272364357 1009 dbSNP
rs1338013572 1019 dbSNP
rs1023581585 1022 dbSNP
rs1470024021 1024 dbSNP
rs1012169747 1025 dbSNP
rs1212011443 1037 dbSNP
rs1250928113 1039 dbSNP
rs929600609 1044 dbSNP
rs566816269 1054 dbSNP
rs974170034 1058 dbSNP
rs960438411 1062 dbSNP
rs1474375284 1069 dbSNP
rs1018477735 1073 dbSNP
rs985614645 1085 dbSNP
rs1035106918 1086 dbSNP
rs999164025 1087 dbSNP
rs955543354 1091 dbSNP
rs1029839301 1094 dbSNP
rs1394212609 1097 dbSNP
rs1436363015 1100 dbSNP
rs565463078 1106 dbSNP
rs902281424 1112 dbSNP
rs1227301949 1119 dbSNP
rs567529027 1124 dbSNP
rs550614244 1129 dbSNP
rs1272862881 1140 dbSNP
rs893301824 1143 dbSNP
rs1039965126 1157 dbSNP
rs756944908 1158 dbSNP
rs912772058 1163 dbSNP
rs531050039 1176 dbSNP
rs1416183269 1181 dbSNP
rs753219163 1183 dbSNP
rs1000639279 1194 dbSNP
rs1423132840 1197 dbSNP
rs1175876146 1206 dbSNP
rs1162163356 1209 dbSNP
rs1416789129 1216 dbSNP
rs1478088860 1225 dbSNP
rs929963542 1226 dbSNP
rs565269611 1229 dbSNP
rs1160693333 1232 dbSNP
rs1383202769 1234 dbSNP
rs905913280 1245 dbSNP
rs1044876768 1258 dbSNP
rs1357449163 1269 dbSNP
rs1413077068 1272 dbSNP
rs918695647 1274 dbSNP
rs36072792 1276 dbSNP
rs962577299 1277 dbSNP
rs916410755 1282 dbSNP
rs990619641 1297 dbSNP
rs1487858749 1299 dbSNP
rs960911044 1309 dbSNP
rs1204484881 1311 dbSNP
rs1258223558 1313 dbSNP
rs1034923279 1316 dbSNP
rs929860717 1317 dbSNP
rs1256156447 1322 dbSNP
rs1310138100 1330 dbSNP
rs1183470467 1352 dbSNP
rs1362432633 1353 dbSNP
rs1453407931 1354 dbSNP
rs1174645471 1355 dbSNP
rs1277295083 1365 dbSNP
rs749087321 1367 dbSNP
rs760319470 1379 dbSNP
rs1319187171 1380 dbSNP
rs966391668 1385 dbSNP
rs1022026256 1386 dbSNP
rs1010602261 1387 dbSNP
rs900225642 1389 dbSNP
rs11884049 1394 dbSNP
rs1361709331 1395 dbSNP
rs910936046 1400 dbSNP
rs1007035308 1413 dbSNP
rs1350013137 1416 dbSNP
rs1194448134 1417 dbSNP
rs891385487 1418 dbSNP
rs767595124 1427 dbSNP
rs1279016866 1432 dbSNP
rs985625202 1432 dbSNP
rs191217466 1435 dbSNP
rs1197184259 1437 dbSNP
rs929990585 1438 dbSNP
rs1418131743 1443 dbSNP
rs1194700722 1445 dbSNP
rs1357684708 1453 dbSNP
rs542949916 1462 dbSNP
rs1173500852 1466 dbSNP
rs552982555 1466 dbSNP
rs1463654761 1474 dbSNP
rs1296511292 1481 dbSNP
rs1466227289 1488 dbSNP
rs1425637449 1491 dbSNP
rs555788919 1499 dbSNP
rs1441875239 1500 dbSNP
rs11546467 1507 dbSNP
rs897153220 1512 dbSNP
rs1372848393 1513 dbSNP
rs186268150 1517 dbSNP
rs1232003306 1525 dbSNP
rs1302499087 1530 dbSNP
rs557212318 1533 dbSNP
rs1168452316 1535 dbSNP
rs1038498808 1536 dbSNP
rs1480126832 1543 dbSNP
rs543511407 1548 dbSNP
rs1427643565 1558 dbSNP
rs1255300733 1563 dbSNP
rs181533930 1567 dbSNP
rs1414237399 1569 dbSNP
rs557598369 1577 dbSNP
rs1193399472 1589 dbSNP
rs1430787742 1591 dbSNP
rs1168475053 1598 dbSNP
rs990673548 1605 dbSNP
rs1462184904 1609 dbSNP
rs956282613 1615 dbSNP
rs138999104 1616 dbSNP
rs1396411832 1617 dbSNP
rs1183453879 1620 dbSNP
rs571987447 1623 dbSNP
rs1242203669 1625 dbSNP
rs1198673502 1628 dbSNP
rs1216220076 1639 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' uguagaUUCUGACGUUCUCAAga 5'
                |||:  | |||||||  
Target 5' ----uaAAGGGGGAAAGAGUU-- 3'
1 - 17
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000409892.1 | 3UTR | UAAAGGGGGAAAGAGUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
133 hsa-miR-4680-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT378771 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT393867 ZDHHC21 zinc finger DHHC-type containing 21 2 4
MIRT446684 C2CD2 C2 calcium dependent domain containing 2 2 2
MIRT447600 MRPL3 mitochondrial ribosomal protein L3 2 2
MIRT450708 RNF152 ring finger protein 152 2 2
MIRT450784 PAPOLG poly(A) polymerase gamma 2 2
MIRT454623 COL23A1 collagen type XXIII alpha 1 chain 2 8
MIRT461620 PTCD3 pentatricopeptide repeat domain 3 2 2
MIRT462695 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT475530 HOXA3 homeobox A3 2 8
MIRT475739 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 2 4
MIRT489676 CYP1A1 cytochrome P450 family 1 subfamily A member 1 2 2
MIRT490610 SLC47A1 solute carrier family 47 member 1 2 2
MIRT493628 HIC2 HIC ZBTB transcriptional repressor 2 2 2
MIRT496152 RPS15A ribosomal protein S15a 2 2
MIRT499232 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT501496 PRICKLE2 prickle planar cell polarity protein 2 2 2
MIRT507163 GAS2L3 growth arrest specific 2 like 3 2 2
MIRT512389 MTRNR2L1 MT-RNR2-like 1 2 4
MIRT514626 MTRNR2L7 MT-RNR2-like 7 2 2
MIRT517474 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT525332 CNGB1 cyclic nucleotide gated channel beta 1 2 2
MIRT526685 BAK1 BCL2 antagonist/killer 1 2 2
MIRT527317 CCR2 C-C motif chemokine receptor 2 2 2
MIRT527608 EYS eyes shut homolog (Drosophila) 2 2
MIRT528794 RAB32 RAB32, member RAS oncogene family 2 2
MIRT531048 TIPARP TCDD inducible poly(ADP-ribose) polymerase 2 2
MIRT532254 TBPL2 TATA-box binding protein like 2 2 2
MIRT533801 TMED7 transmembrane p24 trafficking protein 7 2 4
MIRT535887 MLEC malectin 2 2
MIRT540704 PDPK1 3-phosphoinositide dependent protein kinase 1 2 4
MIRT544645 PHF8 PHD finger protein 8 2 4
MIRT545760 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT555310 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 2
MIRT555877 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 4
MIRT559507 ARID5B AT-rich interaction domain 5B 2 2
MIRT560448 SLC30A7 solute carrier family 30 member 7 2 2
MIRT561262 ZIK1 zinc finger protein interacting with K protein 1 2 2
MIRT561795 PAWR pro-apoptotic WT1 regulator 2 2
MIRT567007 KLHL15 kelch like family member 15 2 2
MIRT569298 SURF6 surfeit 6 2 2
MIRT570606 MTRNR2L11 MT-RNR2-like 11 2 2
MIRT572888 ADCY2 adenylate cyclase 2 2 2
MIRT573119 ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 2 2
MIRT608332 ZNF670 zinc finger protein 670 2 6
MIRT614942 KCNK5 potassium two pore domain channel subfamily K member 5 2 2
MIRT615324 ERN1 endoplasmic reticulum to nucleus signaling 1 2 2
MIRT618441 ZNF800 zinc finger protein 800 2 2
MIRT620110 HARBI1 harbinger transposase derived 1 2 2
MIRT626008 ZNF517 zinc finger protein 517 2 2
MIRT626626 SLC30A6 solute carrier family 30 member 6 2 2
MIRT627842 POU3F1 POU class 3 homeobox 1 2 2
MIRT628386 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 2 2
MIRT629305 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT629864 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT630444 IDE insulin degrading enzyme 2 2
MIRT631854 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT633173 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT633477 ZNF724P zinc finger protein 724 2 2
MIRT634395 PLSCR1 phospholipid scramblase 1 2 2
MIRT635538 TRIM72 tripartite motif containing 72 2 2
MIRT635821 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT636169 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT636797 CYB5D1 cytochrome b5 domain containing 1 2 2
MIRT637952 IVD isovaleryl-CoA dehydrogenase 2 2
MIRT645136 HES2 hes family bHLH transcription factor 2 2 2
MIRT645667 ADK adenosine kinase 2 2
MIRT646148 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT647004 NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 2 2
MIRT648187 C2orf68 chromosome 2 open reading frame 68 2 2
MIRT650090 TERF2 telomeric repeat binding factor 2 2 2
MIRT650329 RTN2 reticulon 2 2 2
MIRT654224 RNF165 ring finger protein 165 2 2
MIRT654545 RAB1A RAB1A, member RAS oncogene family 2 2
MIRT656457 MAPK14 mitogen-activated protein kinase 14 2 2
MIRT656828 KLF8 Kruppel like factor 8 2 2
MIRT657112 ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein like 2 2 2
MIRT657930 GATSL2 cytosolic arginine sensor for mTORC1 subunit 2 2 2
MIRT659375 CREG2 cellular repressor of E1A stimulated genes 2 2 2
MIRT659833 CARHSP1 calcium regulated heat stable protein 1 2 2
MIRT662108 LACTB lactamase beta 2 4
MIRT662789 TBC1D25 TBC1 domain family member 25 2 2
MIRT669501 ARL3 ADP ribosylation factor like GTPase 3 2 2
MIRT669759 ZNF101 zinc finger protein 101 2 4
MIRT669800 GAN gigaxonin 2 2
MIRT670050 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT670299 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT670388 EMP2 epithelial membrane protein 2 2 2
MIRT672862 C22orf29 retrotransposon Gag like 10 2 2
MIRT672890 FXN frataxin 2 2
MIRT673210 C10orf76 chromosome 10 open reading frame 76 2 2
MIRT674001 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT674163 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 2 2
MIRT674502 TIRAP TIR domain containing adaptor protein 2 2
MIRT675470 NUBPL nucleotide binding protein like 2 2
MIRT675671 TMOD2 tropomodulin 2 2 2
MIRT676006 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT676074 TIMM50 translocase of inner mitochondrial membrane 50 2 2
MIRT676386 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT676764 SNX2 sorting nexin 2 2 2
MIRT676896 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT676978 ZNF708 zinc finger protein 708 2 2
MIRT677236 C15orf40 chromosome 15 open reading frame 40 2 2
MIRT677369 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT677464 PDLIM3 PDZ and LIM domain 3 2 2
MIRT678081 EIF2A eukaryotic translation initiation factor 2A 2 2
MIRT678093 ATCAY ATCAY, caytaxin 2 2
MIRT678324 FBLIM1 filamin binding LIM protein 1 2 2
MIRT678417 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678521 ZNF347 zinc finger protein 347 2 2
MIRT678700 TRIP11 thyroid hormone receptor interactor 11 2 2
MIRT678829 PDE6A phosphodiesterase 6A 2 2
MIRT679991 RUNDC1 RUN domain containing 1 2 2
MIRT680751 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT681249 ZNF383 zinc finger protein 383 2 2
MIRT681422 GTF3C6 general transcription factor IIIC subunit 6 2 2
MIRT681948 SLC19A3 solute carrier family 19 member 3 2 2
MIRT689278 C5AR2 complement component 5a receptor 2 2 2
MIRT690389 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT691845 OSCAR osteoclast associated, immunoglobulin-like receptor 2 2
MIRT693863 IYD iodotyrosine deiodinase 2 2
MIRT696002 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT701930 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT702341 KLHL7 kelch like family member 7 2 2
MIRT703557 FKBP14 FK506 binding protein 14 2 2
MIRT705033 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT706341 STAC2 SH3 and cysteine rich domain 2 2 2
MIRT709671 RGP1 RGP1 homolog, RAB6A GEF complex partner 1 2 2
MIRT711212 EFHB EF-hand domain family member B 2 2
MIRT718342 PURA purine rich element binding protein A 2 2
MIRT722755 SIRPB2 signal regulatory protein beta 2 2 2
MIRT723535 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 2 2
MIRT724498 BFAR bifunctional apoptosis regulator 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4680-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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