miRTarBase - #MIRT658214


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pre-miRNA Information
pre-miRNA hsa-mir-628   
Genomic Coordinates chr15: 55372940 - 55373034
Synonyms MIRN628, hsa-mir-628, MIR628
Description Homo sapiens miR-628 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-628-3p
Sequence 61| UCUAGUAAGAGUGGCAGUCGA |81
Evidence Experimental
Experiments Microarray
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 7 15 - 55372968 29233923 MiREDiBase
A-to-I 8 15 - 55372967 29233923 MiREDiBase
C-to-U 19 15 - 55372956 20591823 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN26969715 1 COSMIC
COSN30123186 10 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1410255602 2 dbSNP
rs1401315366 3 dbSNP
rs1322836365 4 dbSNP
rs1158103480 8 dbSNP
rs1216611749 11 dbSNP
rs749619551 13 dbSNP
rs778157225 18 dbSNP
rs756600789 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol FBXO21   
Synonyms FBX21
Description F-box protein 21
Transcript NM_015002   
Other Transcripts NM_033624   
Expression
Putative miRNA Targets on FBXO21
3'UTR of FBXO21
(miRNA target sites are highlighted)		 
>FBXO21|NM_015002|3'UTR
   1 AGTCTAGAGAGGACATTGCACCTTTGCTGCTGCTGCTATCTTCCAAGAGAACGGGACTCCGGAAGAAGACGTCTCCACGG
  81 AGCCCTCGGGACCTGCTGCACCAGGAAAGCCACTCCACCAGTAGTGCTGGTTGCCTCCTACTAAGTTTAAATACCGTGTG
 161 CTCTTCCCCAGCTGCAAAGACAATGTTGCTCTCCGCCTACACTAGTGAATTAATCTGAAAGGCACTGTGTCAGTGGCATG
 241 GCTTGTATGCTTGTCCTGTGGTGACAGTTTGTGACATTCTGTCTTCATGAGGTCTCACAGTCGACGCTCCTGTAATCATT
 321 CTTTGTATTCACTCCATTCCCCTGTCTGTCTGCATTTGTCTCAGAACATTTCCTTGGCTGGACAGATGGGGTTATGCATT
 401 TGCAATAATTTCCTTCTGATTTCTCTGTGGAACGTGTTCGGTCCCGAGTGAGGACTGTGTGTCTTTTTACCCTGAAGTTA
 481 GTTGCATATTCAGAGGTAAAGTTGTGTGCTATCTTGGCAGCATCTTAGAGATGGAGACATTAACAAGCTAATGGTAATTA
 561 GAATCATTTGAATTTATTTTTTTCTAATATGTGAAACACAGATTTCAAGTGTTTTATCTTTTTTTTTTAAATTTAAATGG
 641 GAATATAACACAGTTTTCCCTTCCATATTCCTCTCTTGAGTTTATGCACATCTCTATAAATCATTAGTTTTCTATTTTAT
 721 TACATAAAATTCTTTTAGAAAATGCAAATAGTGAACTTTGTGAATGGATTTTTCCATACTCATCTACAATTCCTCCATTT
 801 TAAATGACTACTTTTATTTTTTAATTTAAAAAATCTACTTCAGTATCATGAGTAGGTCTTACATCAGTGATGGGTTCTTT
 881 TTGTAGTGAGACATACAAATCTGATGTTAATGTTTGCTCTTAGAAGTCATACTCCATGGTCTTCAAAGACCAAAAAATGA
 961 GGTTTTGCTTTTGTAATCAGGAAAAAAAAAAATTAATGAACCTTAAAAAAAAAAAAAAAGGTTTTGAAGGGAAAAAAAGT
1041 GGTTTCACACCTCTTGTTATTCCTTAGAGTCACTTCAAGGCCTGTTTGAATGTGGCAGGTTAGAAAGAGAGAGAATGTCT
1121 TTCATTTGAAGAGTGTTGGACTTGTGTGAAAGGAGATGTGCGTGTTGGAATCTGCTTTTCCAAGCCGCCAGGGTCCTGAC
1201 GGCAGCAGGACGAAGCCTGTTGTGGCGTCTTCTGGGAAAGCCTGACCGTGTGTTCGGACGGCACTGGCTCCTTTCCGAAG
1281 TTCTCAGTAACTGAGCCCAGAGTAACTGCACGCCTTTGTGCAGCTCTGGAGCTCCACCAACTCTCGGCCTGCCAGTTCTC
1361 AAGCGAGCTAATCTTGTCATTAATCGATAGAAGCTAACTTCCGAAGTTAGGACCTAGTTACTTTGCTCTCAACATTTAAA
1441 ATAATGCAGTTGCTCTAGTGAATGGGGCGTTAGGGGCCTGTCTCTGCACCTGTCTGTCCATCTGCATGCAGTATTCTCAC
1521 CCATGTTGAATGCCTGCTGCTTGTTTACCCTTTGGAAACCCTGGGGTGACCAAGGTTTGGAAAGCCACCTGAGACCACTT
1601 CATAGCAAGGGAAGGCTTTAAGCAGTTACTAGAAAGAGATGGGGATTTGGCCCCTGGCTCCTCCAGCCTGAATGAGCTAT
1681 TTAATCCACTGTCCATGTTCCTCATCAGTCAAATCCAAAGTCAAAGGATTTGAACCTGCATCTGGAAACGTAACCACTCA
1761 CAGCACCTGGCCCGCCAAGGTTGGGAGGATTGTACACTACTTTCATTTAAAGGGGAAAGTTTGATAATACGGAATTAATT
1841 AATATGAATGAGATGCATTAATAAGAACCTGAGCATGCTGAGAGTTGCAATTGTTGGTTTTCTGGTTTGATTGATTTCCT
1921 TTTTTCTTAGACACATCAAAGTCAAGAAAGATGGTTTTACCTTTACTGACCCAGCTGTACATATGTATCTAGACTGTTTT
2001 TAAATGTCTTTCTTCATGAATGCTTCATGGGGCTCCAGGAAGCCTGTATCACCTGTGTAAGTTGGTATTTGGGCACTTTA
2081 TATTTTTCTAAAAACGTGTTTTGGATCCTGTACTCTAATAAATCATAAGTTTCTTTTTAAAAATTTTCCAAAACTTTTCT
2161 CCATTTTAAAAAGCCCTGTTATAAACGTTGAACTTTCACAATGTTAAAATGTTAAATATTTGGATATAGCAACTTCTTTT
2241 CTCTTCAAATGAATGCCAAGATTTTTTTGTACAATGATTAATAAATGGAACTTATCCAGAGAAACCAAAAAAAAAAAAAA
2321 AA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agCUGACGGU-GAGAAUGAUCu 5'
            |:|| : | |  ||||||| 
Target 5' aaGGCTTTAAGCAGTTACTAGa 3'
 1612 - 1633 147.00 -11.00
2 
miRNA  3' agCUGACGGUGAGAAUGAUCu 5'
            ||:| || :|:|| :||| 
Target 5' ttGATTTCCTTTTTTCTTAGa 3'
 1911 - 1931 119.00 -12.20
3 
miRNA  3' agCUGACGGUGAGAAUGAUcu 5'
            |::| ::|| :|||||:  
Target 5' atGGTT-TTACCTTTACTGac 3'
 1951 - 1970 118.00 -10.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26976178 1 COSMIC
COSN31570812 33 COSMIC
COSN20077846 37 COSMIC
COSN30628985 38 COSMIC
COSN31577975 54 COSMIC
COSN13371318 60 COSMIC
COSN30135596 99 COSMIC
COSN30539748 114 COSMIC
COSN31612231 155 COSMIC
COSN31593309 200 COSMIC
COSN20110180 618 COSMIC
COSN505736 979 COSMIC
COSN5931793 995 COSMIC
COSN20110176 1031 COSMIC
COSN8960362 1112 COSMIC
COSN6408124 1198 COSMIC
COSN5931792 1307 COSMIC
COSN20092658 1469 COSMIC
COSN14974110 1534 COSMIC
COSN25012126 1555 COSMIC
COSN21495806 1560 COSMIC
COSN20617250 1866 COSMIC
COSN8585418 2020 COSMIC
COSN31520839 2144 COSMIC
COSN15306207 2150 COSMIC
COSN22985907 2159 COSMIC
COSN28679913 2187 COSMIC
COSN31582939 2201 COSMIC
COSN26650111 2256 COSMIC
COSN28733890 2269 COSMIC
COSN26553576 2272 COSMIC
COSN15743991 2276 COSMIC
COSN25709310 2355 COSMIC
COSN22420207 2423 COSMIC
COSN29166889 2427 COSMIC
COSN27770216 2591 COSMIC
COSN15745757 2654 COSMIC
COSN16450128 2787 COSMIC
COSN20599322 2924 COSMIC
COSN6408123 3384 COSMIC
COSN29878581 3391 COSMIC
COSN16333355 3593 COSMIC
COSN5316214 3671 COSMIC
COSN29068602 3768 COSMIC
COSN15747056 3771 COSMIC
COSN7609534 3882 COSMIC
COSN16333552 3939 COSMIC
COSN20602386 4039 COSMIC
rs3741472 3179 GWAS
rs73206033 3350 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1245263965 1 dbSNP
rs776485711 4 dbSNP
rs768635405 5 dbSNP
rs1483582918 7 dbSNP
rs1488846530 8 dbSNP
rs201541949 9 dbSNP
rs1215031228 12 dbSNP
rs780469332 15 dbSNP
rs772245855 17 dbSNP
rs368453191 27 dbSNP
rs1369279148 28 dbSNP
rs1281020640 29 dbSNP
rs779238459 33 dbSNP
rs757795966 38 dbSNP
rs1398902585 41 dbSNP
rs749828449 42 dbSNP
rs1299841168 43 dbSNP
rs1313077437 46 dbSNP
rs778098926 49 dbSNP
rs371485880 52 dbSNP
rs1032588561 53 dbSNP
rs868354353 56 dbSNP
rs1226385244 59 dbSNP
rs745369198 60 dbSNP
rs1317372390 61 dbSNP
rs1241133178 62 dbSNP
rs146699544 66 dbSNP
rs534569031 70 dbSNP
rs1374515379 71 dbSNP
rs1216038669 78 dbSNP
rs912637758 79 dbSNP
rs565656700 87 dbSNP
rs779465939 88 dbSNP
rs552030026 95 dbSNP
rs1051653041 105 dbSNP
rs1160949451 108 dbSNP
rs1379044085 113 dbSNP
rs1418554414 114 dbSNP
rs367549767 120 dbSNP
rs1360471738 124 dbSNP
rs921437326 125 dbSNP
rs1301999646 136 dbSNP
rs1169663046 140 dbSNP
rs974263649 141 dbSNP
rs941629842 147 dbSNP
rs569756225 156 dbSNP
rs771398032 158 dbSNP
rs749666377 161 dbSNP
rs1314097162 163 dbSNP
rs1208322631 171 dbSNP
rs1237215404 176 dbSNP
rs778152956 181 dbSNP
rs887207780 183 dbSNP
rs1047016894 184 dbSNP
rs756326832 188 dbSNP
rs117329242 190 dbSNP
rs980555433 191 dbSNP
rs1196687275 194 dbSNP
rs1426699373 195 dbSNP
rs529954135 198 dbSNP
rs969170579 223 dbSNP
rs1429109379 224 dbSNP
rs189536832 231 dbSNP
rs1250042536 241 dbSNP
rs991363146 249 dbSNP
rs1227324631 250 dbSNP
rs1375986915 265 dbSNP
rs937282797 267 dbSNP
rs560821019 268 dbSNP
rs1336174097 276 dbSNP
rs1275471482 280 dbSNP
rs1294559290 301 dbSNP
rs185116394 302 dbSNP
rs1217583244 306 dbSNP
rs892404739 314 dbSNP
rs1354379172 324 dbSNP
rs1278182746 330 dbSNP
rs1308359751 332 dbSNP
rs1329144353 340 dbSNP
rs1256560752 344 dbSNP
rs4767501 344 dbSNP
rs1194821586 345 dbSNP
rs1249014476 346 dbSNP
rs1476740363 347 dbSNP
rs1190201824 351 dbSNP
rs967115754 367 dbSNP
rs1419777020 372 dbSNP
rs1478608139 376 dbSNP
rs779549151 381 dbSNP
rs1020462338 386 dbSNP
rs1394068499 387 dbSNP
rs1399316292 391 dbSNP
rs1297452306 392 dbSNP
rs998861899 402 dbSNP
rs1391076771 403 dbSNP
rs781548345 404 dbSNP
rs1461878429 409 dbSNP
rs755171668 416 dbSNP
rs932748533 423 dbSNP
rs1220725318 431 dbSNP
rs1167128936 432 dbSNP
rs755592622 433 dbSNP
rs61938670 436 dbSNP
rs371804453 439 dbSNP
rs559689534 440 dbSNP
rs1450456452 446 dbSNP
rs1439834819 469 dbSNP
rs1220115781 470 dbSNP
rs181304606 474 dbSNP
rs1478576334 487 dbSNP
rs1028689339 492 dbSNP
rs1038521547 504 dbSNP
rs997091179 506 dbSNP
rs1164841192 517 dbSNP
rs900096876 530 dbSNP
rs1404698757 532 dbSNP
rs1275623792 536 dbSNP
rs1230863633 538 dbSNP
rs908780451 539 dbSNP
rs1019769362 546 dbSNP
rs1333533165 550 dbSNP
rs1296543860 551 dbSNP
rs1340210522 552 dbSNP
rs1245975143 554 dbSNP
rs1286338458 567 dbSNP
rs1354783264 569 dbSNP
rs1279695556 577 dbSNP
rs1286049597 578 dbSNP
rs1213877320 584 dbSNP
rs773268093 584 dbSNP
rs939028260 585 dbSNP
rs927621758 587 dbSNP
rs980481718 588 dbSNP
rs1008813577 590 dbSNP
rs969137753 620 dbSNP
rs1472395903 627 dbSNP
rs577220783 628 dbSNP
rs1421584513 629 dbSNP
rs200178847 629 dbSNP
rs540355081 629 dbSNP
rs71783953 629 dbSNP
rs956784641 629 dbSNP
rs989292127 629 dbSNP
rs1396518395 631 dbSNP
rs1030917672 632 dbSNP
rs1356538620 637 dbSNP
rs1237249432 645 dbSNP
rs543995331 651 dbSNP
rs1284691566 653 dbSNP
rs931454417 665 dbSNP
rs1253696926 670 dbSNP
rs1460914293 671 dbSNP
rs898483204 677 dbSNP
rs1029632916 678 dbSNP
rs1239924749 684 dbSNP
rs1437766889 687 dbSNP
rs1176787945 689 dbSNP
rs1390086353 695 dbSNP
rs763881928 702 dbSNP
rs1400386725 717 dbSNP
rs1414258215 723 dbSNP
rs937236892 724 dbSNP
rs140806648 732 dbSNP
rs150944126 737 dbSNP
rs1038446891 740 dbSNP
rs1307834596 747 dbSNP
rs1362312005 750 dbSNP
rs1181475817 755 dbSNP
rs1253876839 762 dbSNP
rs1343924262 766 dbSNP
rs775181037 778 dbSNP
rs1259762519 782 dbSNP
rs535319190 792 dbSNP
rs767153142 798 dbSNP
rs34790541 805 dbSNP
rs1197959035 811 dbSNP
rs113955663 818 dbSNP
rs1433814541 823 dbSNP
rs1201179991 826 dbSNP
rs1376075746 828 dbSNP
rs957139822 833 dbSNP
rs939605309 834 dbSNP
rs921566721 835 dbSNP
rs974421442 836 dbSNP
rs1044768866 841 dbSNP
rs964248006 842 dbSNP
rs1464433472 848 dbSNP
rs947723300 851 dbSNP
rs367935689 855 dbSNP
rs538366267 857 dbSNP
rs1387993131 862 dbSNP
rs768168006 862 dbSNP
rs1330083704 867 dbSNP
rs879175681 871 dbSNP
rs989270743 874 dbSNP
rs569700341 877 dbSNP
rs951627596 881 dbSNP
rs1197822375 883 dbSNP
rs923779756 883 dbSNP
rs1265959139 887 dbSNP
rs1489457817 899 dbSNP
rs1234661838 901 dbSNP
rs987379468 902 dbSNP
rs1372899837 903 dbSNP
rs574425114 916 dbSNP
rs1194628830 926 dbSNP
rs1028891166 929 dbSNP
rs1440052724 931 dbSNP
rs1477041208 932 dbSNP
rs996789596 936 dbSNP
rs1025834987 944 dbSNP
rs1369490185 951 dbSNP
rs1459905082 953 dbSNP
rs1319019764 962 dbSNP
rs1402546495 978 dbSNP
rs1389419989 979 dbSNP
rs1382993677 980 dbSNP
rs1158279233 981 dbSNP
rs1435648284 982 dbSNP
rs1299618406 991 dbSNP
rs1217774122 993 dbSNP
rs1338056107 993 dbSNP
rs1397256930 994 dbSNP
rs1192210596 995 dbSNP
rs1477972381 997 dbSNP
rs1243235296 998 dbSNP
rs1313164951 998 dbSNP
rs1194640482 999 dbSNP
rs1444780312 1001 dbSNP
rs1460981698 1004 dbSNP
rs1264842780 1005 dbSNP
rs1283019583 1007 dbSNP
rs12228888 1019 dbSNP
rs1217519890 1020 dbSNP
rs1253755594 1020 dbSNP
rs36075086 1020 dbSNP
rs370693551 1020 dbSNP
rs562134448 1020 dbSNP
rs57717777 1020 dbSNP
rs1211139176 1022 dbSNP
rs201744776 1031 dbSNP
rs142024020 1032 dbSNP
rs398116908 1032 dbSNP
rs964048911 1032 dbSNP
rs995536284 1032 dbSNP
rs898604085 1033 dbSNP
rs1047688632 1036 dbSNP
rs397825210 1039 dbSNP
rs5801216 1039 dbSNP
rs945909738 1040 dbSNP
rs1055683480 1050 dbSNP
rs1003773280 1053 dbSNP
rs1001498756 1054 dbSNP
rs1288254293 1055 dbSNP
rs907248609 1056 dbSNP
rs1256865653 1063 dbSNP
rs1484424969 1067 dbSNP
rs1180546377 1068 dbSNP
rs762239254 1074 dbSNP
rs1243059184 1076 dbSNP
rs1440862955 1079 dbSNP
rs1179924428 1080 dbSNP
rs1046059599 1086 dbSNP
rs12298149 1095 dbSNP
rs1324759475 1102 dbSNP
rs1297723470 1112 dbSNP
rs914915900 1115 dbSNP
rs1335852815 1117 dbSNP
rs1377458807 1121 dbSNP
rs1377545902 1125 dbSNP
rs1053501223 1129 dbSNP
rs1311496169 1131 dbSNP
rs544431879 1134 dbSNP
rs1374739223 1144 dbSNP
rs935089970 1145 dbSNP
rs923775261 1153 dbSNP
rs913046543 1158 dbSNP
rs1420758716 1160 dbSNP
rs759088079 1161 dbSNP
rs1458566017 1162 dbSNP
rs1201047207 1168 dbSNP
rs1474744978 1186 dbSNP
rs188640216 1187 dbSNP
rs974670689 1192 dbSNP
rs1426757228 1198 dbSNP
rs567108494 1200 dbSNP
rs547327760 1201 dbSNP
rs921680735 1207 dbSNP
rs575465626 1211 dbSNP
rs963973859 1212 dbSNP
rs965693434 1219 dbSNP
rs1353937131 1226 dbSNP
rs527578857 1227 dbSNP
rs1060232 1229 dbSNP
rs1221934384 1233 dbSNP
rs562788823 1235 dbSNP
rs913017373 1247 dbSNP
rs911600772 1248 dbSNP
rs987439939 1250 dbSNP
rs544156604 1255 dbSNP
rs951690408 1256 dbSNP
rs1026210304 1259 dbSNP
rs559490760 1260 dbSNP
rs773830855 1264 dbSNP
rs1034389724 1266 dbSNP
rs1247979059 1267 dbSNP
rs1277614462 1269 dbSNP
rs771365920 1270 dbSNP
rs1060233 1275 dbSNP
rs532512293 1276 dbSNP
rs1423949511 1280 dbSNP
rs1478680292 1284 dbSNP
rs893450127 1286 dbSNP
rs1311311356 1295 dbSNP
rs1447655631 1296 dbSNP
rs35295142 1302 dbSNP
rs369653550 1306 dbSNP
rs1355461345 1309 dbSNP
rs1324241713 1310 dbSNP
rs1010543565 1311 dbSNP
rs891727826 1312 dbSNP
rs1302774571 1328 dbSNP
rs1054248993 1336 dbSNP
rs563741666 1340 dbSNP
rs935037012 1345 dbSNP
rs1229414239 1346 dbSNP
rs1339255615 1346 dbSNP
rs1475910364 1347 dbSNP
rs902248733 1354 dbSNP
rs921795536 1362 dbSNP
rs1038798363 1364 dbSNP
rs921770352 1365 dbSNP
rs944461648 1376 dbSNP
rs1234375208 1378 dbSNP
rs543910588 1385 dbSNP
rs764210144 1386 dbSNP
rs1273765650 1389 dbSNP
rs1241340504 1394 dbSNP
rs1214340648 1395 dbSNP
rs941965380 1402 dbSNP
rs1291573556 1403 dbSNP
rs909861377 1405 dbSNP
rs983151020 1406 dbSNP
rs575129326 1410 dbSNP
rs184708731 1425 dbSNP
rs1361331259 1430 dbSNP
rs541366736 1434 dbSNP
rs962850092 1448 dbSNP
rs1034505725 1452 dbSNP
rs1026140018 1462 dbSNP
rs1449271399 1467 dbSNP
rs770141983 1468 dbSNP
rs980145468 1469 dbSNP
rs970853924 1473 dbSNP
rs1023823622 1475 dbSNP
rs971521521 1477 dbSNP
rs572662151 1488 dbSNP
rs111627657 1490 dbSNP
rs1024706553 1500 dbSNP
rs558283915 1514 dbSNP
rs894045017 1521 dbSNP
rs1032624896 1522 dbSNP
rs527306864 1523 dbSNP
rs1463538288 1524 dbSNP
rs763302152 1532 dbSNP
rs891670537 1533 dbSNP
rs1032920349 1541 dbSNP
rs193063380 1544 dbSNP
rs1163521019 1554 dbSNP
rs1189426276 1565 dbSNP
rs999590541 1587 dbSNP
rs1000152550 1598 dbSNP
rs748514817 1603 dbSNP
rs900317868 1609 dbSNP
rs1381024719 1610 dbSNP
rs933078775 1611 dbSNP
rs1157016066 1613 dbSNP
rs1384610306 1622 dbSNP
rs1415390672 1625 dbSNP
rs189858062 1629 dbSNP
rs185778889 1633 dbSNP
rs1404463053 1637 dbSNP
rs1452593828 1639 dbSNP
rs1038861217 1647 dbSNP
rs3741468 1650 dbSNP
rs112840969 1653 dbSNP
rs1467117634 1655 dbSNP
rs755226859 1664 dbSNP
rs1047814355 1666 dbSNP
rs983420310 1668 dbSNP
rs1261056141 1673 dbSNP
rs148490942 1679 dbSNP
rs1317690482 1682 dbSNP
rs1286625330 1691 dbSNP
rs553858978 1692 dbSNP
rs974278734 1700 dbSNP
rs1363381263 1703 dbSNP
rs1478484455 1706 dbSNP
rs941647538 1710 dbSNP
rs1174640483 1711 dbSNP
rs927438818 1722 dbSNP
rs1427670694 1731 dbSNP
rs1304701264 1732 dbSNP
rs980260157 1737 dbSNP
rs971845887 1738 dbSNP
rs1403154299 1746 dbSNP
rs534351027 1749 dbSNP
rs757146114 1750 dbSNP
rs1024399386 1753 dbSNP
rs989334045 1754 dbSNP
rs753751174 1761 dbSNP
rs866171360 1764 dbSNP
rs1234987201 1766 dbSNP
rs1281033748 1767 dbSNP
rs1322521967 1768 dbSNP
rs1219083765 1770 dbSNP
rs3741469 1773 dbSNP
rs1000101860 1774 dbSNP
rs552308151 1775 dbSNP
rs1452357779 1777 dbSNP
rs1201835231 1779 dbSNP
rs759559698 1785 dbSNP
rs572636766 1792 dbSNP
rs532565637 1795 dbSNP
rs1156504835 1802 dbSNP
rs1033003917 1804 dbSNP
rs773096491 1806 dbSNP
rs900433961 1808 dbSNP
rs999785007 1815 dbSNP
rs570048061 1816 dbSNP
rs1418767733 1821 dbSNP
rs966744102 1824 dbSNP
rs1030011718 1825 dbSNP
rs1008739290 1830 dbSNP
rs1388048084 1831 dbSNP
rs1300900545 1837 dbSNP
rs890319641 1838 dbSNP
rs1344541068 1843 dbSNP
rs763925603 1845 dbSNP
rs1400320784 1848 dbSNP
rs756005158 1853 dbSNP
rs866840303 1854 dbSNP
rs1305658211 1868 dbSNP
rs1226637404 1873 dbSNP
rs550346570 1875 dbSNP
rs993676402 1881 dbSNP
rs898821144 1887 dbSNP
rs1266965308 1888 dbSNP
rs1266613927 1890 dbSNP
rs1490248154 1896 dbSNP
rs557910766 1897 dbSNP
rs1486237445 1906 dbSNP
rs1194785941 1912 dbSNP
rs530172102 1924 dbSNP
rs1038786484 1926 dbSNP
rs1193060746 1932 dbSNP
rs1369612852 1935 dbSNP
rs1425992203 1937 dbSNP
rs1005999678 1939 dbSNP
rs1364497232 1949 dbSNP
rs1419964499 1954 dbSNP
rs887655420 1966 dbSNP
rs1359582017 1968 dbSNP
rs941590406 1970 dbSNP
rs1342206734 1981 dbSNP
rs1248175581 1982 dbSNP
rs927549520 1984 dbSNP
rs1358935059 1989 dbSNP
rs1310911130 1998 dbSNP
rs752459771 1999 dbSNP
rs1382236678 2009 dbSNP
rs1363454220 2010 dbSNP
rs1186362673 2015 dbSNP
rs1257410937 2016 dbSNP
rs950240618 2017 dbSNP
rs917447434 2024 dbSNP
rs1046414430 2025 dbSNP
rs949395256 2027 dbSNP
rs1343142468 2038 dbSNP
rs374444272 2041 dbSNP
rs1452706279 2044 dbSNP
rs1303212496 2048 dbSNP
rs988893871 2050 dbSNP
rs1450380153 2061 dbSNP
rs561479387 2067 dbSNP
rs916660347 2069 dbSNP
rs956349430 2095 dbSNP
rs767208315 2096 dbSNP
rs568206851 2097 dbSNP
rs964589627 2109 dbSNP
rs1017525647 2114 dbSNP
rs1256985392 2115 dbSNP
rs1463009279 2126 dbSNP
rs548235508 2126 dbSNP
rs1202310698 2129 dbSNP
rs925482285 2138 dbSNP
rs1457820862 2142 dbSNP
rs762216825 2143 dbSNP
rs1376931758 2144 dbSNP
rs1405255732 2145 dbSNP
rs954549652 2152 dbSNP
rs541582587 2154 dbSNP
rs527999269 2163 dbSNP
rs193008368 2167 dbSNP
rs1176455573 2169 dbSNP
rs1431126197 2170 dbSNP
rs1468075567 2173 dbSNP
rs1263918433 2177 dbSNP
rs1401013459 2178 dbSNP
rs993230855 2182 dbSNP
rs545362716 2183 dbSNP
rs898935886 2186 dbSNP
rs1258517797 2187 dbSNP
rs1213398054 2197 dbSNP
rs1031024376 2201 dbSNP
rs1482485949 2211 dbSNP
rs773885915 2215 dbSNP
rs997123629 2217 dbSNP
rs964378093 2223 dbSNP
rs1263051620 2225 dbSNP
rs1255846535 2259 dbSNP
rs1037287897 2260 dbSNP
rs1205956546 2262 dbSNP
rs1228760797 2262 dbSNP
rs1230696931 2269 dbSNP
rs1309822117 2269 dbSNP
rs1191380636 2271 dbSNP
rs1017303846 2272 dbSNP
rs1005928070 2279 dbSNP
rs1424170987 2296 dbSNP
rs1001835734 2308 dbSNP
rs1217503465 2320 dbSNP
rs904903684 2329 dbSNP
rs1172560736 2330 dbSNP
rs1355632212 2332 dbSNP
rs1314335508 2334 dbSNP
rs1441622720 2347 dbSNP
rs1044651794 2358 dbSNP
rs1303981862 2358 dbSNP
rs866742885 2360 dbSNP
rs950375619 2363 dbSNP
rs1393992990 2375 dbSNP
rs1047577349 2383 dbSNP
rs1340612790 2385 dbSNP
rs917412107 2386 dbSNP
rs1053710319 2396 dbSNP
rs1306410218 2401 dbSNP
rs1463434417 2406 dbSNP
rs1293419180 2416 dbSNP
rs1349577639 2430 dbSNP
rs1489723377 2434 dbSNP
rs934710041 2434 dbSNP
rs1371299940 2438 dbSNP
rs926029360 2439 dbSNP
rs1045713903 2442 dbSNP
rs531790459 2452 dbSNP
rs575672870 2453 dbSNP
rs1164313690 2458 dbSNP
rs1190331396 2463 dbSNP
rs964703585 2476 dbSNP
rs765852458 2477 dbSNP
rs910578790 2480 dbSNP
rs987391216 2488 dbSNP
rs1327354945 2492 dbSNP
rs1433409062 2494 dbSNP
rs954799722 2495 dbSNP
rs1026121516 2499 dbSNP
rs763388366 2508 dbSNP
rs1361884274 2510 dbSNP
rs993737289 2513 dbSNP
rs569079931 2515 dbSNP
rs1356766754 2519 dbSNP
rs1015961345 2521 dbSNP
rs1221250821 2523 dbSNP
rs1001950379 2524 dbSNP
rs904851362 2525 dbSNP
rs1481876692 2526 dbSNP
rs1448519022 2528 dbSNP
rs1025091898 2543 dbSNP
rs1241393356 2548 dbSNP
rs1473089695 2551 dbSNP
rs1034419975 2555 dbSNP
rs1256730721 2559 dbSNP
rs1184230864 2562 dbSNP
rs1387139578 2564 dbSNP
rs1014481138 2566 dbSNP
rs1163168631 2569 dbSNP
rs34882593 2585 dbSNP
rs896075332 2593 dbSNP
rs936781872 2597 dbSNP
rs1402743410 2598 dbSNP
rs1053253003 2600 dbSNP
rs934808245 2604 dbSNP
rs904731041 2609 dbSNP
rs967307850 2611 dbSNP
rs1242132517 2612 dbSNP
rs1279760013 2615 dbSNP
rs542316127 2616 dbSNP
rs1221793779 2619 dbSNP
rs976342965 2621 dbSNP
rs964305557 2623 dbSNP
rs1017239747 2624 dbSNP
rs573360510 2626 dbSNP
rs149725284 2627 dbSNP
rs1183075016 2634 dbSNP
rs1330603808 2643 dbSNP
rs1471297751 2647 dbSNP
rs1157143521 2648 dbSNP
rs1461946150 2651 dbSNP
rs984483212 2653 dbSNP
rs770166013 2654 dbSNP
rs1404614481 2655 dbSNP
rs1451208860 2663 dbSNP
rs1328957176 2668 dbSNP
rs1337124410 2679 dbSNP
rs910523850 2681 dbSNP
rs1439538101 2684 dbSNP
rs1278628312 2685 dbSNP
rs1395301401 2686 dbSNP
rs1323983904 2687 dbSNP
rs987893973 2688 dbSNP
rs1165127845 2690 dbSNP
rs1471907475 2697 dbSNP
rs1225175180 2700 dbSNP
rs933210789 2708 dbSNP
rs919173274 2714 dbSNP
rs1199902713 2719 dbSNP
rs1251365069 2724 dbSNP
rs951813686 2724 dbSNP
rs748569848 2728 dbSNP
rs3741470 2734 dbSNP
rs1251450446 2736 dbSNP
rs1480962462 2738 dbSNP
rs993338160 2745 dbSNP
rs116960429 2746 dbSNP
rs186689325 2748 dbSNP
rs980477266 2750 dbSNP
rs183599993 2752 dbSNP
rs969124041 2755 dbSNP
rs1055146897 2756 dbSNP
rs936690743 2764 dbSNP
rs1406469048 2769 dbSNP
rs1024620384 2774 dbSNP
rs1013672969 2777 dbSNP
rs570070147 2781 dbSNP
rs1228038224 2787 dbSNP
rs1253048260 2790 dbSNP
rs896036324 2791 dbSNP
rs1194212744 2794 dbSNP
rs1032337311 2795 dbSNP
rs999130794 2796 dbSNP
rs1201997806 2797 dbSNP
rs1240847675 2798 dbSNP
rs747159841 2799 dbSNP
rs368104451 2807 dbSNP
rs1433006032 2815 dbSNP
rs550161100 2824 dbSNP
rs945560131 2825 dbSNP
rs1459970363 2829 dbSNP
rs779594452 2834 dbSNP
rs1308343724 2843 dbSNP
rs191874492 2844 dbSNP
rs1441501707 2862 dbSNP
rs1373134222 2863 dbSNP
rs140781202 2873 dbSNP
rs1364699497 2874 dbSNP
rs1382639673 2875 dbSNP
rs1043258940 2877 dbSNP
rs147273113 2878 dbSNP
rs910829781 2881 dbSNP
rs1297008086 2882 dbSNP
rs532676958 2883 dbSNP
rs1390218563 2885 dbSNP
rs1488349995 2887 dbSNP
rs1206102657 2888 dbSNP
rs772251411 2889 dbSNP
rs1427290398 2893 dbSNP
rs889201166 2896 dbSNP
rs1159354603 2897 dbSNP
rs1421826286 2898 dbSNP
rs745931273 2910 dbSNP
rs1349003917 2912 dbSNP
rs933307027 2922 dbSNP
rs919306855 2929 dbSNP
rs777806577 2937 dbSNP
rs1382648020 2941 dbSNP
rs527922072 2945 dbSNP
rs971939753 2946 dbSNP
rs569167354 2947 dbSNP
rs1381607871 2948 dbSNP
rs1337370126 2952 dbSNP
rs1383607235 2962 dbSNP
rs1248333124 2964 dbSNP
rs1378822524 2969 dbSNP
rs1026062270 2974 dbSNP
rs565328973 2977 dbSNP
rs756025016 2978 dbSNP
rs1244366155 2979 dbSNP
rs557372567 2981 dbSNP
rs752513036 2986 dbSNP
rs1255475694 2987 dbSNP
rs969125966 2990 dbSNP
rs749990893 2991 dbSNP
rs780928403 2995 dbSNP
rs545730361 3005 dbSNP
rs1160964233 3008 dbSNP
rs894377190 3009 dbSNP
rs1032957666 3010 dbSNP
rs1261887868 3011 dbSNP
rs1000865147 3022 dbSNP
rs1351100504 3023 dbSNP
rs991961886 3035 dbSNP
rs956555258 3043 dbSNP
rs531836616 3047 dbSNP
rs999078273 3048 dbSNP
rs1234796549 3049 dbSNP
rs945458806 3061 dbSNP
rs1315501868 3063 dbSNP
rs968975852 3064 dbSNP
rs1349886635 3070 dbSNP
rs1021760357 3074 dbSNP
rs1007738004 3076 dbSNP
rs377529232 3076 dbSNP
rs574218070 3076 dbSNP
rs1236412919 3077 dbSNP
rs186936711 3080 dbSNP
rs1319113115 3083 dbSNP
rs1402054626 3084 dbSNP
rs542181609 3085 dbSNP
rs1176886911 3086 dbSNP
rs3741471 3087 dbSNP
rs1468186337 3090 dbSNP
rs1175333115 3095 dbSNP
rs930287317 3100 dbSNP
rs918926909 3109 dbSNP
rs1300104114 3112 dbSNP
rs1427796492 3126 dbSNP
rs1348880015 3131 dbSNP
rs897809028 3134 dbSNP
rs183585739 3139 dbSNP
rs1284365331 3140 dbSNP
rs1478024571 3145 dbSNP
rs1373117300 3148 dbSNP
rs1195268973 3149 dbSNP
rs1347890953 3152 dbSNP
rs749875588 3153 dbSNP
rs765793391 3163 dbSNP
rs796738441 3174 dbSNP
rs560120368 3178 dbSNP
rs3741472 3179 dbSNP
rs1482540825 3184 dbSNP
rs557623139 3185 dbSNP
rs1270749273 3193 dbSNP
rs1000521567 3194 dbSNP
rs1218544879 3197 dbSNP
rs1340046706 3198 dbSNP
rs1270796401 3199 dbSNP
rs1368908817 3200 dbSNP
rs1429375276 3201 dbSNP
rs1367819303 3212 dbSNP
rs968041534 3212 dbSNP
rs947873408 3213 dbSNP
rs917780946 3216 dbSNP
rs36046246 3221 dbSNP
rs1338623199 3222 dbSNP
rs1294794812 3224 dbSNP
rs992304127 3225 dbSNP
rs956495035 3226 dbSNP
rs538149338 3228 dbSNP
rs923577535 3231 dbSNP
rs901923687 3232 dbSNP
rs1489793843 3234 dbSNP
rs1040472948 3235 dbSNP
rs191929630 3236 dbSNP
rs1242566778 3237 dbSNP
rs1486826178 3240 dbSNP
rs968923464 3241 dbSNP
rs777138587 3242 dbSNP
rs1415686516 3255 dbSNP
rs1021874341 3258 dbSNP
rs1332650906 3259 dbSNP
rs556619823 3260 dbSNP
rs536674029 3263 dbSNP
rs370225153 3264 dbSNP
rs1346255110 3268 dbSNP
rs1433474192 3269 dbSNP
rs1319178308 3274 dbSNP
rs1476564222 3285 dbSNP
rs918906644 3293 dbSNP
rs1316642523 3295 dbSNP
rs1030530042 3307 dbSNP
rs997982383 3311 dbSNP
rs1036419454 3314 dbSNP
rs1227492006 3323 dbSNP
rs77840118 3328 dbSNP
rs1036281496 3333 dbSNP
rs1448571943 3335 dbSNP
rs1213520944 3337 dbSNP
rs1006186436 3339 dbSNP
rs752919011 3342 dbSNP
rs73206033 3350 dbSNP
rs143937326 3352 dbSNP
rs1471944440 3359 dbSNP
rs1209190527 3375 dbSNP
rs1438284127 3376 dbSNP
rs1259918098 3377 dbSNP
rs1409133812 3377 dbSNP
rs1200543559 3378 dbSNP
rs561495337 3383 dbSNP
rs369471898 3384 dbSNP
rs61938669 3389 dbSNP
rs1234093853 3390 dbSNP
rs12824193 3390 dbSNP
rs28524926 3391 dbSNP
rs150469882 3392 dbSNP
rs1282733889 3394 dbSNP
rs78605938 3394 dbSNP
rs1447772504 3396 dbSNP
rs1338171503 3402 dbSNP
rs1336814088 3410 dbSNP
rs1333941924 3412 dbSNP
rs1168906135 3414 dbSNP
rs1187093233 3414 dbSNP
rs1204345352 3414 dbSNP
rs1226415162 3414 dbSNP
rs1267368320 3414 dbSNP
rs1279819268 3414 dbSNP
rs1280790121 3414 dbSNP
rs1324219790 3414 dbSNP
rs1338293421 3414 dbSNP
rs1352552570 3414 dbSNP
rs1399402371 3414 dbSNP
rs1413465585 3414 dbSNP
rs1422982771 3414 dbSNP
rs1446790052 3414 dbSNP
rs1471324273 3414 dbSNP
rs761025781 3414 dbSNP
rs1008385697 3416 dbSNP
rs112159160 3420 dbSNP
rs571813677 3427 dbSNP
rs551518453 3434 dbSNP
rs1407717481 3440 dbSNP
rs1056318017 3445 dbSNP
rs1287528445 3445 dbSNP
rs935034171 3446 dbSNP
rs11068363 3448 dbSNP
rs1411225029 3449 dbSNP
rs188253376 3453 dbSNP
rs967701118 3457 dbSNP
rs1239837566 3458 dbSNP
rs776746605 3459 dbSNP
rs369864131 3464 dbSNP
rs796362536 3464 dbSNP
rs1273906842 3467 dbSNP
rs910916005 3471 dbSNP
rs1203406535 3477 dbSNP
rs986777658 3482 dbSNP
rs184056609 3483 dbSNP
rs978671061 3493 dbSNP
rs953669384 3499 dbSNP
rs1486148197 3501 dbSNP
rs1222424917 3502 dbSNP
rs191815400 3508 dbSNP
rs1020230632 3517 dbSNP
rs976281238 3522 dbSNP
rs966058109 3523 dbSNP
rs1374508507 3529 dbSNP
rs1365952295 3532 dbSNP
rs1311972517 3534 dbSNP
rs746010880 3535 dbSNP
rs1445188655 3539 dbSNP
rs1224362825 3546 dbSNP
rs1018945964 3553 dbSNP
rs1270875532 3553 dbSNP
rs1344456677 3553 dbSNP
rs1241358143 3555 dbSNP
rs1014955077 3558 dbSNP
rs1376842560 3559 dbSNP
rs1212005168 3561 dbSNP
rs1007606422 3564 dbSNP
rs1451573536 3564 dbSNP
rs778810720 3576 dbSNP
rs1049715178 3577 dbSNP
rs1447200967 3579 dbSNP
rs1437992143 3580 dbSNP
rs887765588 3589 dbSNP
rs769756659 3590 dbSNP
rs1012553878 3591 dbSNP
rs528888193 3593 dbSNP
rs138285940 3594 dbSNP
rs1291593392 3595 dbSNP
rs748015118 3596 dbSNP
rs898058423 3599 dbSNP
rs1320263835 3602 dbSNP
rs116420127 3615 dbSNP
rs1297052174 3617 dbSNP
rs1360450341 3619 dbSNP
rs935168899 3623 dbSNP
rs902384791 3624 dbSNP
rs1206228546 3627 dbSNP
rs1043475245 3628 dbSNP
rs937085209 3638 dbSNP
rs946479342 3639 dbSNP
rs749714385 3649 dbSNP
rs925783563 3657 dbSNP
rs1162306793 3659 dbSNP
rs1253576736 3664 dbSNP
rs1367651023 3669 dbSNP
rs1454169666 3669 dbSNP
rs540368956 3672 dbSNP
rs1386363260 3689 dbSNP
rs185468745 3698 dbSNP
rs780981917 3702 dbSNP
rs1383676334 3710 dbSNP
rs976642655 3713 dbSNP
rs1221073649 3716 dbSNP
rs1354751659 3722 dbSNP
rs1340246360 3724 dbSNP
rs1240217060 3727 dbSNP
rs180863654 3730 dbSNP
rs1327732469 3735 dbSNP
rs1018914849 3738 dbSNP
rs962183117 3739 dbSNP
rs1015074723 3744 dbSNP
rs1353533597 3753 dbSNP
rs1179738632 3757 dbSNP
rs544298978 3761 dbSNP
rs866541419 3768 dbSNP
rs1221489665 3769 dbSNP
rs1364868082 3789 dbSNP
rs1409596249 3795 dbSNP
rs952147975 3796 dbSNP
rs1024017314 3800 dbSNP
rs1467710878 3802 dbSNP
rs11068362 3805 dbSNP
rs898032626 3807 dbSNP
rs761667588 3809 dbSNP
rs1014519401 3810 dbSNP
rs1034938299 3825 dbSNP
rs575489977 3829 dbSNP
rs754830101 3830 dbSNP
rs895452783 3832 dbSNP
rs1228294897 3842 dbSNP
rs902337338 3846 dbSNP
rs1296068714 3848 dbSNP
rs1418868652 3853 dbSNP
rs1395524744 3862 dbSNP
rs1254990049 3871 dbSNP
rs1480765047 3874 dbSNP
rs1178136854 3875 dbSNP
rs1431410974 3877 dbSNP
rs1043594698 3878 dbSNP
rs946426919 3881 dbSNP
rs937021358 3882 dbSNP
rs1488717199 3884 dbSNP
rs889548307 3885 dbSNP
rs1214829590 3897 dbSNP
rs575528447 3899 dbSNP
rs555734210 3904 dbSNP
rs190355051 3905 dbSNP
rs1369081192 3915 dbSNP
rs1409671172 3916 dbSNP
rs913073023 3920 dbSNP
rs751276462 3921 dbSNP
rs1311002512 3926 dbSNP
rs976610019 3927 dbSNP
rs922300079 3935 dbSNP
rs1216919422 3946 dbSNP
rs1300024670 3947 dbSNP
rs1307626372 3970 dbSNP
rs151066771 3971 dbSNP
rs376974121 3974 dbSNP
rs372996038 3975 dbSNP
rs1248339871 3976 dbSNP
rs5801215 3976 dbSNP
rs940959723 3983 dbSNP
rs1190589300 3984 dbSNP
rs1341911759 3991 dbSNP
rs574025908 3992 dbSNP
rs1170710714 3995 dbSNP
rs1388554690 4003 dbSNP
rs757936524 4005 dbSNP
rs1275902311 4009 dbSNP
rs553832634 4011 dbSNP
rs867339722 4015 dbSNP
rs1352080195 4016 dbSNP
rs1434897952 4024 dbSNP
rs749978695 4025 dbSNP
rs1293521445 4026 dbSNP
rs1399089324 4028 dbSNP
rs1375807403 4032 dbSNP
rs534308255 4036 dbSNP
rs1294877208 4038 dbSNP
rs533173345 4039 dbSNP
rs185640525 4060 dbSNP
rs764582477 4087 dbSNP
rs1175368787 4088 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000427718.2 | 3UTR | GAAAGAGAUGGGGAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.588 1.3e-3 0.553 2.5e-3 24 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.517 4.1e-3 0.595 8.5e-4 25 Click to see details
GSE21687 Ependynoma primary tumors -0.277 1.3e-2 -0.340 3.0e-3 64 Click to see details
GSE19783 ER+ ER+ breast cancer -0.478 1.7e-2 -0.547 6.3e-3 20 Click to see details
GSE19783 ER- ER- breast cancer 0.229 2.1e-2 0.213 3.0e-2 79 Click to see details
GSE17306 Multiple myeloma 0.235 5.2e-2 0.154 1.5e-1 49 Click to see details
GSE42095 Differentiated embryonic stem cells 0.321 6.8e-2 0.295 8.6e-2 23 Click to see details
GSE21849 B cell lymphoma 0.274 7.5e-2 0.253 9.3e-2 29 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.269 1.3e-1 0.355 6.2e-2 20 Click to see details
GSE27834 Pluripotent stem cells 0.297 1.3e-1 0.162 2.7e-1 16 Click to see details
GSE28260 Renal cortex and medulla -0.265 1.9e-1 -0.275 1.8e-1 13 Click to see details
GSE26953 Aortic valvular endothelial cells 0.187 1.9e-1 0.248 1.2e-1 24 Click to see details
GSE19536 Breast cancer 0.073 2.4e-1 0.017 4.3e-1 100 Click to see details
GSE17498 Multiple myeloma -0.103 2.6e-1 -0.050 3.8e-1 40 Click to see details
GSE19350 CNS germ cell tumors 0.184 2.8e-1 0.098 3.8e-1 12 Click to see details
GSE32688 Pancreatic cancer -0.073 3.5e-1 0.005 4.9e-1 32 Click to see details
GSE14794 Lymphoblastoid cells -0.017 4.4e-1 -0.049 3.2e-1 90 Click to see details
GSE38226 Liver fibrosis 0.006 4.9e-1 -0.047 4.2e-1 21 Click to see details
GSE38226 Liver fibrosis 0.006 4.9e-1 -0.047 4.2e-1 21 Click to see details
GSE38226 Liver fibrosis 0.006 4.9e-1 -0.047 4.2e-1 21 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
PAAD -0.995 0 -1.000 0.5 4 Click to see details
KICH 0.382 0.04 0.343 0.06 22 Click to see details
KIRP -0.253 0.09 -0.293 0.06 29 Click to see details
STAD -0.255 0.1 -0.357 0.03 28 Click to see details
BLCA -0.258 0.16 -0.402 0.05 17 Click to see details
PCPG 0.878 0.16 1.000 0.5 3 Click to see details
LUAD 0.268 0.23 0.055 0.44 10 Click to see details
BRCA -0.097 0.29 -0.273 0.06 34 Click to see details
LUSC -0.074 0.34 -0.020 0.45 35 Click to see details
PRAD 0.056 0.37 -0.026 0.44 36 Click to see details
ESCA -0.085 0.4 0.227 0.25 11 Click to see details
UCEC 0.053 0.42 0.079 0.38 18 Click to see details
KIRC 0.032 0.42 0.136 0.2 40 Click to see details
CHOL 0.066 0.44 0.464 0.15 7 Click to see details
HNSC -0.015 0.47 -0.174 0.16 35 Click to see details
LIHC 0.011 0.47 -0.011 0.47 49 Click to see details
THCA 0.003 0.49 -0.022 0.43 58 Click to see details
CESC 0.001 0.5 0.500 0.33 3 Click to see details
CESC 0.001 0.5 0.500 0.33 3 Click to see details
27 hsa-miR-628-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT039584 CDC14A cell division cycle 14A 1 1
MIRT039585 AGO1 argonaute 1, RISC catalytic component 2 3
MIRT039586 TGFBRAP1 transforming growth factor beta receptor associated protein 1 1 1
MIRT039587 LRP6 LDL receptor related protein 6 1 1
MIRT071876 BTF3L4 basic transcription factor 3 like 4 2 2
MIRT097443 JMY junction mediating and regulatory protein, p53 cofactor 2 4
MIRT100100 ABT1 activator of basal transcription 1 2 8
MIRT147692 CBX4 chromobox 4 2 2
MIRT408248 PURA purine rich element binding protein A 2 2
MIRT442047 LRAT lecithin retinol acyltransferase 2 2
MIRT444412 RAB3IP RAB3A interacting protein 2 2
MIRT452599 REPIN1 replication initiator 1 2 2
MIRT469515 RBFOX2 RNA binding protein, fox-1 homolog 2 2 8
MIRT498192 AKR1B10 aldo-keto reductase family 1 member B10 2 2
MIRT500151 CREBBP CREB binding protein 2 2
MIRT507319 FAM60A SIN3-HDAC complex associated factor 2 6
MIRT508343 ZNF273 zinc finger protein 273 2 6
MIRT520480 TRIM13 tripartite motif containing 13 2 2
MIRT522461 MMP16 matrix metallopeptidase 16 2 4
MIRT547116 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 2
MIRT548675 CRNKL1 crooked neck pre-mRNA splicing factor 1 2 2
MIRT553756 TARBP2 TARBP2, RISC loading complex RNA binding subunit 2 4
MIRT559437 ARSJ arylsulfatase family member J 2 2
MIRT610490 GPC4 glypican 4 2 2
MIRT644682 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT658214 FBXO21 F-box protein 21 2 2
MIRT756083 TP53 tumor protein p53 4 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-628 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-628-3p Cisplatin 5460033 NSC119875 approved resistant High Tongue Squamous Cell Carcinoma cell line (Tca8113)
hsa-miR-628-3p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7, LY2)
hsa-miR-628-3p Erlotinib 176870 NSC718781 approved sensitive High Epithelial Cancer cell line (A549, UKY-29, H460, H1975, H1650, H3255, PC-9, H358)
hsa-miR-628-3p Siop Treatment Protocol sensitive High Nephroblastoma tissue
hsa-miR-628-3p Sunitinib 5329102 NSC750690 approved resistant High Metastatic Renal Cell Carcinoma tissue and cell line (Caki-2)
hsa-miR-628-3p Chemotherapy sensitive High Epithelial Ovarian Cancer tissue
hsa-miR-628-3p Platinum-based doublet chemotherapy resistant Low Lung Adenocarcinoma tissue
hsa-miR-628-3p Doxorubicin 31703 NSC123127 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-miR-628-3p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (TAMR8)
hsa-miR-628-3p Aromatase Inhibitor sensitive Low Breast Cancer cell line (MCF-7)
hsa-miR-628-3p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-628-3p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-628-3p Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-628-3p Platinum 23939 sensitive High High-Grade Serous Ovarian Cancer tissue
hsa-miR-628-3p Cisplatin 5460033 NSC119875 approved sensitive High Bladder Cancer cell line (CDDP-R-BOY, CDDP-R-T24)
hsa-miR-628-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-628-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-628-3p Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-miR-628-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-628-3p Tamoxifen 2733525 NSC180973 approved resistant cell line (TamR8)
hsa-miR-628-3p Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-628-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-628-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-628-3p Docetaxel+Cisplatin+5-Fluorouracil sensitive tissue (hypopharyngeal squamous cell carcinoma)

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