miRTarBase - #MIRT658708


—
pre-miRNA Information
pre-miRNA hsa-mir-4796   
Genomic Coordinates chr3: 114743445 - 114743525
Description Homo sapiens miR-4796 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4796-5p
Sequence 9| UGUCUAUACUCUGUCACUUUAC |30
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1466952984 15 dbSNP
rs887451291 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol EMB   
Synonyms GP70
Description embigin
Transcript NM_198449   
Expression
Putative miRNA Targets on EMB
3'UTR of EMB
(miRNA target sites are highlighted)		 
>EMB|NM_198449|3'UTR
   1 ATACAAAACATCATGTCGAGAATCATTGGAAGATATACAGAGTTCGTATTTCAGCTTTGTTTATCCTTCCTGTTAAGAGC
  81 CTCTGAGTTTTTAGTTTTAAAAGGATGAAAAGCTTATGCAACATGCTCAGCAGGAGCTTCATCAACGATATATGTCAGAT
 161 CTAAAGGTATATTTTCATTCTGTAATTATGTTACATAAAAGCAATGTAAATCAGAATAAATATGTTAGACCAGAATAAAA
 241 TTAATTATATTCTGGTCTTCAAAGGACACACAGAACAGATATCAGCAGAATCACTTAATACTTCATAGAACAAAAATCAC
 321 TCAAAACCTGTTTATAACCAAAGAATTCATGAAAAAGAAAGCCTTTGCCATTTGTCTTAGAAAGTTATTTTTTAAAAAAA
 401 AATCATACTTACTATTAGTATCTATGGAAGTATATGTAACAATTTTTATGTAAAGGTCATCTTTCTGTGATAGTGAAAAA
 481 ATATGTCTTTACTAAGTTGAAATGAATACTTTCTGCCTTTGCTAATGATAGTTATTCTACAATCTCCACAAGAAAAATAT
 561 ACCTTTTATCCGGAAATATTGGTTTAAGGCAAATAAATAAAACTGTGCTTGCTCTAAAGCTCTGCACTACAAAAGCAAAT
 641 TTTCCAGTCTTTATTCCACTCATAACCACTGCTTTCCCCACCAGGCTAAAGTGCTTCTTAGTCTTAAATAGGGTTTTTAA
 721 CTTCATAAGGTACACCATTGTTTATGTTTTAGGGTGCAGGTCCATATAGTCGTAATACTTAAAACACTGCTACACTGATG
 801 CTTTTGTGGCTCATGGTTTCCTGGTTCTTTGATTTAACACCTGGCTTCCTGGTATCTATGGCTGGTTAAATATCTAAACC
 881 TGCATTATTAGTGCTTTACAATAATAATTCCCTTGACTGAAGTCCAGAAATACTAAAGCACTTCTTTTTTATTGCTGTGA
 961 ATGCCTTAGACTTATCTTCCAAAATAGGATACTTCGTTTCTATTGCATATATAACTGAAATATTTTATAAACTCACTGTA
1041 ATCAAATCTTATAAAATCTGAATCAACATGAAAAGTTGTCAATGCTTGAATGAATACTAAAATCATACCACAAGATACTA
1121 GATAACATAAATGACCATGAAGTGTCCCACTGCTCAAAGGGCAACAACTTTAAGAACAGAAGCAAAGAGTGGTGGTGTGG
1201 AACCCAAGATTCTTGGCGACTAGGGAATTTAAAGGTTGGGGAGGAGGAATTCAATGATTTGACAAGAAATACTTTATAAA
1281 AATTTGCTCCATGTATTGGCTAAGAAAAATATAATAAAATTTTGGTAGTGAAAATTGTATCACTAATGTTTACCAATATT
1361 ACTAGTATGAATAATACACATAAGGTAGTGACTTGGAAGCTGCTCAATACTTTGTTGCTATAACAAAATGCAATATTTTG
1441 TTGTAAAGCATCTTAACTACACATATAAGTTTGCTGAACTTGAATACATCCCGGTAATGGCAAACTTCATTTTATTCTTG
1521 GTTTTCATTTTATTCTGGTCTCAGGGCCATACATTTATTTTAGTTTAATTAATTATTATTTTGACAACATTACTTGGGTA
1601 ATATCTATATAATGGTAGATAACCAATCAGTTAGCTTAATTAATCTAAGCTATTTGAATTCAGGGAAATATTAGTCAAAT
1681 CTGCTGTTTGACTAAATACAATTCAAAGCAGTGTATTTGTGACTTGGAATATAGAACACAAACAAATGTGTAACCCATCT
1761 GCAGTATGCATTCTTCCATTTTACCACCACTAACCATTGAGGCTCATACAATTTTCAAGCAACAAGCATTGCTTCCCAAA
1841 GGTAAAATAATCAGGAATATTTCTATAGTAAATGGAGTTTTTAATTGGCAATACTGTTTATTTTTTTCTAGCAAAGACAA
1921 TTTATCTCAGTAACCTTAAATAGGAAAAGTACTCAAAAATTAAAGTTGACTTTTGGCTTTTTGTAGTCTCTCTGGAGGAC
2001 TTCCAGAAAATTACCACTGTTGGATTTTAATCTGCTTCCATTAACCAATCTTACAGAGATGATAAATGAATTAACTAATA
2081 TTGACCAAATATAAATTGACTGCAAATAATAAGCCGCATAAAAGTTGAAGTAGGAAAACTACTCCAAGTTTATATATTAG
2161 GCACCTTGGGGAATTCTCTTAGTCTTTCCAGCTAACAAGGATTTTCAGCATAATAAGTAGATTTAATGATGGCATAAAAT
2241 TCCCAGATACTTTCATATACATTTTTTGCCAAAGTGTAAATCTTCTCCTTTTGCAGTCTTTTTGTTATTATCCCAACATC
2321 TAGCTGCTCAGGCCCTAATTTAGAACTCATTCTGATATTTTCTTCTTCTGTATTAATTAATACTTATGGGTCATGAATCC
2401 CTGCTCCTTTGACCTTTTTAATAGCTCATGAATCCATCCCATTGCCTCCCCAACTCTGCCCACACCTGCTGCAACACTAA
2481 TGCCTTGATTTTCCTACCTCAGTCTCCTTTTCTATTAATCCCTCTTTTGCGTGGCTGCCTGAGTCCACTTTCTCAAACAC
2561 AAACCTCACTATGCAACTTTGGAATCTCTGTAGGCTCACCTTTGCCATTTCTTAATATTGCATTCTCCAAATTGCTAATC
2641 TCTATCCAGTCTCTTGAACTAGACTTGGCACATGGAGATTCCGCTCAGAAAGTGCTCTTCACACTTCTACCTGCTTGACT
2721 AACCCCAGATTATCTTTCAAGACTTTAATCTGATCTTGTGTCTTAGAGAAGCCCCCATACCTGGTAGAGCATGTACCATC
2801 TTACATGCTTAAATAACTCCACATTTATTTGTGTTTATTACTCTGTGTTATAAATATACATTTGTTGGTCTCTCTCTTGG
2881 ATTATTTTGTTTCTTTGTCCTGTAACTACCACTGAAAGGGTGCAATACAGCTTTCTTGAAATGTGTATTGAACGGATGAA
2961 TGTATAAATAAAAATTAAATTTTGTAAATTTCTGCTTATTCTTAGAAAAAGAATCTAAATTGTGACAAATCAGAATTGAA
3041 AAAAGTATTCTAATAAAGAAAAACAAGCTTTTATAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cauuuCACUG--UCUCAUAUCUgu 5'
               |||||  :|| ||||||  
Target 5' tatttGTGACTTGGAATATAGAac 3'
 1714 - 1737 143.00 -10.70
2 
miRNA  3' caUUUCACUGUCU---CAUAUCUGu 5'
            |::||| |||:    ||||| | 
Target 5' ttAGGGTG-CAGGTCCATATAGTCg 3'
 749 - 772 123.00 -11.80
3 
miRNA  3' caUUUCACUGUCUCAUAUCUgu 5'
            |:||||::  :||:|:||  
Target 5' aaAGAGTGGT--GGTGTGGAac 3'
 1184 - 1203 112.00 -13.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN508078 8 COSMIC
COSN31503691 15 COSMIC
COSN30126222 17 COSMIC
COSN28754661 18 COSMIC
COSN30508599 18 COSMIC
COSN30452410 45 COSMIC
COSN30732070 46 COSMIC
COSN26974926 47 COSMIC
COSN167464 59 COSMIC
COSN30480435 65 COSMIC
COSN30531600 80 COSMIC
COSN30467480 94 COSMIC
COSN7945262 112 COSMIC
COSN30114779 125 COSMIC
COSN26649120 126 COSMIC
COSN30521743 128 COSMIC
COSN30461935 134 COSMIC
COSN19631689 146 COSMIC
COSN20684172 158 COSMIC
COSN31600233 180 COSMIC
COSN30538195 228 COSMIC
COSN20891221 231 COSMIC
COSN31484681 233 COSMIC
COSN28204082 236 COSMIC
COSN1316640 342 COSMIC
COSN30538185 351 COSMIC
COSN28119232 387 COSMIC
COSN31549925 393 COSMIC
COSN23632522 394 COSMIC
COSN8226390 395 COSMIC
COSN31488291 404 COSMIC
COSN9449935 427 COSMIC
COSN17977640 475 COSMIC
COSN31570660 504 COSMIC
COSN2108673 570 COSMIC
COSN2108672 724 COSMIC
COSN8226389 755 COSMIC
COSN216873 841 COSMIC
COSN14882067 972 COSMIC
COSN21390277 995 COSMIC
COSN29334619 1085 COSMIC
COSN9449934 1182 COSMIC
COSN23987691 1342 COSMIC
COSN23987695 1356 COSMIC
COSN15662800 1413 COSMIC
COSN203494 1443 COSMIC
COSN2108671 1680 COSMIC
COSN5077158 1684 COSMIC
COSN15574353 1909 COSMIC
COSN16621791 2048 COSMIC
COSN6299274 2190 COSMIC
COSN20101206 2476 COSMIC
COSN28361384 2663 COSMIC
COSN16880862 2724 COSMIC
COSN9449933 2988 COSMIC
COSN6299273 2996 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1345112095 1 dbSNP
rs1273303494 10 dbSNP
rs771644442 14 dbSNP
rs778758183 17 dbSNP
rs371398269 18 dbSNP
rs1464501574 20 dbSNP
rs773278365 26 dbSNP
rs1192864870 28 dbSNP
rs1409020010 30 dbSNP
rs1177598812 32 dbSNP
rs781683671 35 dbSNP
rs1422553115 36 dbSNP
rs757508909 37 dbSNP
rs752114034 41 dbSNP
rs778099152 44 dbSNP
rs367704753 45 dbSNP
rs752747919 46 dbSNP
rs565107969 53 dbSNP
rs4030567 59 dbSNP
rs1466276810 65 dbSNP
rs1189457561 74 dbSNP
rs573055621 84 dbSNP
rs1157007590 89 dbSNP
rs1416161931 112 dbSNP
rs1427165453 138 dbSNP
rs1425758008 139 dbSNP
rs1171826617 143 dbSNP
rs16879125 146 dbSNP
rs536543166 150 dbSNP
rs1461401982 151 dbSNP
rs1163357655 153 dbSNP
rs998468467 157 dbSNP
rs369171068 172 dbSNP
rs867200593 176 dbSNP
rs1188822871 185 dbSNP
rs1359425337 189 dbSNP
rs1397605582 195 dbSNP
rs1313133993 201 dbSNP
rs979052770 205 dbSNP
rs1231409284 216 dbSNP
rs573592743 220 dbSNP
rs1239931967 223 dbSNP
rs1331333585 231 dbSNP
rs942633845 241 dbSNP
rs556637015 246 dbSNP
rs537172747 249 dbSNP
rs189963790 254 dbSNP
rs1485005783 256 dbSNP
rs3193458 267 dbSNP
rs1183771755 270 dbSNP
rs1257343199 271 dbSNP
rs1314503732 279 dbSNP
rs1475048015 281 dbSNP
rs1049102474 282 dbSNP
rs1279987010 285 dbSNP
rs1157696434 286 dbSNP
rs930699927 301 dbSNP
rs551045596 313 dbSNP
rs1346182831 315 dbSNP
rs1354583939 317 dbSNP
rs1300189362 327 dbSNP
rs1290199266 338 dbSNP
rs919363785 343 dbSNP
rs1436176406 352 dbSNP
rs1283685123 362 dbSNP
rs1315166236 373 dbSNP
rs1361514000 386 dbSNP
rs972255873 387 dbSNP
rs534914348 393 dbSNP
rs1052977 394 dbSNP
rs200980145 394 dbSNP
rs116032159 395 dbSNP
rs1032626908 396 dbSNP
rs796688887 396 dbSNP
rs529501414 401 dbSNP
rs1405203953 403 dbSNP
rs552039290 403 dbSNP
rs1176347260 412 dbSNP
rs561860038 414 dbSNP
rs967100267 414 dbSNP
rs1432698051 417 dbSNP
rs1020028393 418 dbSNP
rs1370889915 418 dbSNP
rs1441434302 420 dbSNP
rs563701699 424 dbSNP
rs1168988994 432 dbSNP
rs1427604367 439 dbSNP
rs1416904777 453 dbSNP
rs1221006660 464 dbSNP
rs192476716 474 dbSNP
rs1347390614 477 dbSNP
rs1209241592 486 dbSNP
rs1277239175 491 dbSNP
rs1483302052 492 dbSNP
rs533347656 502 dbSNP
rs1039556787 516 dbSNP
rs3933097 524 dbSNP
rs1489207350 525 dbSNP
rs888392048 528 dbSNP
rs1049072622 529 dbSNP
rs930670387 542 dbSNP
rs541536668 546 dbSNP
rs1307176441 552 dbSNP
rs573116277 557 dbSNP
rs1293746972 562 dbSNP
rs1230192708 571 dbSNP
rs919331556 572 dbSNP
rs780330836 577 dbSNP
rs769472499 578 dbSNP
rs777657239 579 dbSNP
rs1438753678 581 dbSNP
rs559550081 588 dbSNP
rs1412936010 594 dbSNP
rs1036820082 599 dbSNP
rs950183003 602 dbSNP
rs1214335440 605 dbSNP
rs917378275 609 dbSNP
rs1453797757 613 dbSNP
rs1213821012 615 dbSNP
rs1251874214 625 dbSNP
rs1466702072 626 dbSNP
rs1190130399 628 dbSNP
rs1308448867 639 dbSNP
rs991700871 640 dbSNP
rs1461318315 646 dbSNP
rs937577228 668 dbSNP
rs1405906057 671 dbSNP
rs926248618 674 dbSNP
rs1166487145 676 dbSNP
rs1423962979 691 dbSNP
rs1322871488 693 dbSNP
rs1327243111 694 dbSNP
rs1416614956 702 dbSNP
rs75524023 709 dbSNP
rs1268760978 711 dbSNP
rs978392340 712 dbSNP
rs1234449363 721 dbSNP
rs1273046310 725 dbSNP
rs141944359 726 dbSNP
rs758065384 729 dbSNP
rs1474541472 731 dbSNP
rs1284571511 732 dbSNP
rs1446045500 735 dbSNP
rs1190516885 737 dbSNP
rs1239021132 739 dbSNP
rs573826021 746 dbSNP
rs745580622 751 dbSNP
rs1475374315 753 dbSNP
rs113661362 754 dbSNP
rs1019952555 755 dbSNP
rs976882383 759 dbSNP
rs1460002404 767 dbSNP
rs965169083 771 dbSNP
rs752697175 772 dbSNP
rs780779746 787 dbSNP
rs746861818 790 dbSNP
rs1342655259 791 dbSNP
rs1480525179 796 dbSNP
rs1415770680 800 dbSNP
rs1249919969 801 dbSNP
rs1229752248 802 dbSNP
rs1354080700 802 dbSNP
rs1224058494 806 dbSNP
rs556932093 811 dbSNP
rs750579329 812 dbSNP
rs1408038110 825 dbSNP
rs767446877 834 dbSNP
rs112373678 836 dbSNP
rs1231492475 836 dbSNP
rs1352367406 838 dbSNP
rs1288930734 840 dbSNP
rs762125210 841 dbSNP
rs1209880858 850 dbSNP
rs1255366002 852 dbSNP
rs751665062 858 dbSNP
rs1364487508 864 dbSNP
rs956350134 866 dbSNP
rs888361318 873 dbSNP
rs1026937292 880 dbSNP
rs764530448 882 dbSNP
rs1435777429 883 dbSNP
rs1176823281 895 dbSNP
rs897790065 898 dbSNP
rs1373977650 908 dbSNP
rs1295064319 912 dbSNP
rs186860881 919 dbSNP
rs763283195 944 dbSNP
rs1308256194 947 dbSNP
rs1393250569 947 dbSNP
rs577543351 963 dbSNP
rs78531300 964 dbSNP
rs1276315686 970 dbSNP
rs895925123 975 dbSNP
rs796710511 980 dbSNP
rs1458388448 985 dbSNP
rs1411997188 991 dbSNP
rs1277950089 992 dbSNP
rs111391136 995 dbSNP
rs1418939618 996 dbSNP
rs1248945953 1002 dbSNP
rs1249720766 1003 dbSNP
rs1437385915 1009 dbSNP
rs937546439 1010 dbSNP
rs1193276275 1014 dbSNP
rs1469254632 1015 dbSNP
rs148128336 1022 dbSNP
rs370006445 1027 dbSNP
rs1173205837 1029 dbSNP
rs1393664669 1035 dbSNP
rs1463798049 1038 dbSNP
rs926134593 1043 dbSNP
rs1396403980 1051 dbSNP
rs1389217180 1052 dbSNP
rs1327300259 1055 dbSNP
rs1375826351 1058 dbSNP
rs978944997 1059 dbSNP
rs1233146616 1066 dbSNP
rs1268775360 1067 dbSNP
rs1300719935 1069 dbSNP
rs946318108 1082 dbSNP
rs1315042803 1094 dbSNP
rs770322716 1103 dbSNP
rs912858784 1108 dbSNP
rs756837127 1110 dbSNP
rs560418463 1111 dbSNP
rs1468919306 1120 dbSNP
rs1193258937 1133 dbSNP
rs555491559 1137 dbSNP
rs1323509612 1138 dbSNP
rs751489373 1163 dbSNP
rs985283706 1170 dbSNP
rs1388740779 1171 dbSNP
rs1157481808 1172 dbSNP
rs1453753841 1174 dbSNP
rs952489267 1175 dbSNP
rs1026820859 1184 dbSNP
rs994057981 1187 dbSNP
rs1439508537 1198 dbSNP
rs1323561300 1201 dbSNP
rs897099962 1203 dbSNP
rs1382624366 1212 dbSNP
rs536165425 1217 dbSNP
rs770309164 1218 dbSNP
rs1014296431 1221 dbSNP
rs1273673927 1223 dbSNP
rs895882352 1233 dbSNP
rs1213136118 1239 dbSNP
rs1271550286 1240 dbSNP
rs866421312 1241 dbSNP
rs1486958875 1246 dbSNP
rs1187278269 1249 dbSNP
rs1261506432 1250 dbSNP
rs1427037367 1255 dbSNP
rs868506338 1263 dbSNP
rs1190709514 1272 dbSNP
rs570290270 1275 dbSNP
rs937430240 1277 dbSNP
rs1162149587 1291 dbSNP
rs35214698 1304 dbSNP
rs1191988964 1311 dbSNP
rs1454021956 1318 dbSNP
rs904677505 1318 dbSNP
rs550431097 1324 dbSNP
rs1466417806 1325 dbSNP
rs546051391 1327 dbSNP
rs4095443 1337 dbSNP
rs111938832 1339 dbSNP
rs946287458 1340 dbSNP
rs4095444 1342 dbSNP
rs746681951 1343 dbSNP
rs1041104862 1353 dbSNP
rs1234871388 1356 dbSNP
rs943752664 1362 dbSNP
rs1346902349 1371 dbSNP
rs1300902908 1372 dbSNP
rs372525189 1373 dbSNP
rs985168088 1378 dbSNP
rs547921839 1379 dbSNP
rs919746402 1385 dbSNP
rs1403652797 1391 dbSNP
rs1305122399 1395 dbSNP
rs1343067167 1399 dbSNP
rs1436398129 1404 dbSNP
rs777234273 1411 dbSNP
rs1313239417 1413 dbSNP
rs1435807993 1420 dbSNP
rs972586403 1427 dbSNP
rs149422440 1430 dbSNP
rs1024925979 1431 dbSNP
rs1375633394 1433 dbSNP
rs1224392531 1437 dbSNP
rs1172148483 1440 dbSNP
rs1451612596 1448 dbSNP
rs1236717181 1457 dbSNP
rs748024134 1465 dbSNP
rs1485511600 1473 dbSNP
rs960029938 1487 dbSNP
rs1034334012 1492 dbSNP
rs13354069 1493 dbSNP
rs904642907 1494 dbSNP
rs1043187178 1500 dbSNP
rs1455324560 1506 dbSNP
rs1010441245 1525 dbSNP
rs867363650 1526 dbSNP
rs1394253051 1527 dbSNP
rs374172658 1537 dbSNP
rs892034329 1549 dbSNP
rs1211517026 1551 dbSNP
rs542810553 1552 dbSNP
rs1443088945 1553 dbSNP
rs188102267 1555 dbSNP
rs1374714726 1564 dbSNP
rs1443385372 1576 dbSNP
rs753786001 1586 dbSNP
rs182966253 1589 dbSNP
rs139372749 1591 dbSNP
rs1347689139 1607 dbSNP
rs868208523 1624 dbSNP
rs1275767538 1628 dbSNP
rs767364223 1630 dbSNP
rs931032505 1635 dbSNP
rs1269248190 1643 dbSNP
rs577606161 1645 dbSNP
rs1235860977 1649 dbSNP
rs2883164 1649 dbSNP
rs1193889263 1670 dbSNP
rs1251969810 1675 dbSNP
rs1341744085 1677 dbSNP
rs1312799542 1681 dbSNP
rs1415997338 1685 dbSNP
rs1169411263 1699 dbSNP
rs1409339667 1704 dbSNP
rs1419909972 1704 dbSNP
rs1168156281 1710 dbSNP
rs1398219423 1712 dbSNP
rs961204414 1713 dbSNP
rs1204666130 1715 dbSNP
rs1311484631 1717 dbSNP
rs917747262 1720 dbSNP
rs1434821532 1721 dbSNP
rs1272310353 1724 dbSNP
rs866100010 1726 dbSNP
rs1397599484 1729 dbSNP
rs1167570565 1734 dbSNP
rs1323499136 1741 dbSNP
rs1254750547 1743 dbSNP
rs1363043862 1752 dbSNP
rs146325189 1759 dbSNP
rs1256648883 1764 dbSNP
rs571776488 1766 dbSNP
rs1213764134 1778 dbSNP
rs555553698 1782 dbSNP
rs1272195513 1787 dbSNP
rs1449540530 1793 dbSNP
rs199814350 1794 dbSNP
rs1194831254 1802 dbSNP
rs535700729 1806 dbSNP
rs1242496542 1809 dbSNP
rs1474927230 1817 dbSNP
rs1191494057 1818 dbSNP
rs1419936244 1821 dbSNP
rs1188733034 1822 dbSNP
rs1165718261 1826 dbSNP
rs570231775 1828 dbSNP
rs1403844470 1838 dbSNP
rs1255285433 1839 dbSNP
rs556626644 1840 dbSNP
rs1184212370 1841 dbSNP
rs1320458749 1847 dbSNP
rs1034298108 1865 dbSNP
rs1438192797 1873 dbSNP
rs1430441619 1889 dbSNP
rs1276934940 1891 dbSNP
rs1271937700 1900 dbSNP
rs1193782395 1909 dbSNP
rs1357877562 1910 dbSNP
rs1234386942 1911 dbSNP
rs1358009083 1916 dbSNP
rs1273320726 1919 dbSNP
rs752526751 1920 dbSNP
rs1353570139 1922 dbSNP
rs1232117184 1924 dbSNP
rs1284503118 1928 dbSNP
rs540086724 1929 dbSNP
rs570863147 1934 dbSNP
rs1021696122 1942 dbSNP
rs1336738223 1954 dbSNP
rs751642190 1975 dbSNP
rs547783988 1976 dbSNP
rs1367969281 1980 dbSNP
rs1471818287 1997 dbSNP
rs1160569467 2000 dbSNP
rs891922326 2007 dbSNP
rs1419520444 2011 dbSNP
rs544342791 2013 dbSNP
rs568602419 2016 dbSNP
rs548641667 2019 dbSNP
rs1377612928 2025 dbSNP
rs1461003866 2034 dbSNP
rs1008449837 2044 dbSNP
rs529121272 2045 dbSNP
rs890065556 2048 dbSNP
rs1338250142 2056 dbSNP
rs1415689892 2066 dbSNP
rs1049420926 2074 dbSNP
rs1279813432 2078 dbSNP
rs1349477884 2080 dbSNP
rs1237443089 2091 dbSNP
rs1282239250 2092 dbSNP
rs1485837599 2096 dbSNP
rs970119220 2103 dbSNP
rs115932865 2105 dbSNP
rs1253977137 2107 dbSNP
rs898172592 2113 dbSNP
rs1184038268 2115 dbSNP
rs765011362 2116 dbSNP
rs1439355372 2118 dbSNP
rs1157014382 2130 dbSNP
rs939785829 2133 dbSNP
rs1435716956 2148 dbSNP
rs1179359919 2150 dbSNP
rs1453023144 2153 dbSNP
rs917731903 2162 dbSNP
rs937921850 2163 dbSNP
rs1332037200 2164 dbSNP
rs926580067 2166 dbSNP
rs1305099958 2168 dbSNP
rs1348395961 2178 dbSNP
rs1233281462 2179 dbSNP
rs1269415371 2180 dbSNP
rs1254214849 2188 dbSNP
rs1341357803 2189 dbSNP
rs192079496 2200 dbSNP
rs1196253949 2217 dbSNP
rs980062299 2220 dbSNP
rs370797827 2221 dbSNP
rs760886258 2229 dbSNP
rs533009444 2232 dbSNP
rs1279376697 2238 dbSNP
rs1021582306 2244 dbSNP
rs576692473 2248 dbSNP
rs1376236501 2257 dbSNP
rs956331730 2259 dbSNP
rs1168928266 2261 dbSNP
rs1398932905 2263 dbSNP
rs1019762661 2271 dbSNP
rs1327580772 2273 dbSNP
rs1371237219 2280 dbSNP
rs1440377795 2283 dbSNP
rs1298951005 2286 dbSNP
rs1327911785 2287 dbSNP
rs1008851434 2293 dbSNP
rs1392451431 2298 dbSNP
rs200159148 2307 dbSNP
rs1250679232 2308 dbSNP
rs1317445007 2313 dbSNP
rs1196797863 2316 dbSNP
rs890035813 2319 dbSNP
rs1161461580 2323 dbSNP
rs186684847 2335 dbSNP
rs1209428259 2343 dbSNP
rs1401261489 2345 dbSNP
rs1430602394 2348 dbSNP
rs995762617 2357 dbSNP
rs1423526879 2358 dbSNP
rs558409138 2364 dbSNP
rs1166438259 2370 dbSNP
rs370001997 2372 dbSNP
rs1156694187 2382 dbSNP
rs1478904818 2387 dbSNP
rs1386941925 2389 dbSNP
rs1382569212 2390 dbSNP
rs1277534146 2407 dbSNP
rs1395385456 2407 dbSNP
rs1338312095 2408 dbSNP
rs183327744 2413 dbSNP
rs1322332756 2414 dbSNP
rs1221125310 2419 dbSNP
rs1487090686 2421 dbSNP
rs1206055983 2424 dbSNP
rs1263162217 2427 dbSNP
rs1487606387 2429 dbSNP
rs1190645730 2432 dbSNP
rs939775591 2438 dbSNP
rs896245899 2457 dbSNP
rs1422717836 2463 dbSNP
rs1023028839 2466 dbSNP
rs1466847080 2475 dbSNP
rs145999923 2476 dbSNP
rs35327819 2477 dbSNP
rs937878553 2478 dbSNP
rs926464120 2483 dbSNP
rs1380050174 2487 dbSNP
rs142365370 2512 dbSNP
rs946653335 2515 dbSNP
rs1318934673 2516 dbSNP
rs1350527944 2516 dbSNP
rs914545094 2517 dbSNP
rs989247381 2519 dbSNP
rs1351875999 2521 dbSNP
rs1213717928 2522 dbSNP
rs1482667050 2530 dbSNP
rs561496333 2531 dbSNP
rs1251993800 2534 dbSNP
rs1419338918 2537 dbSNP
rs1290763223 2559 dbSNP
rs541900831 2563 dbSNP
rs1378263490 2564 dbSNP
rs1020151291 2571 dbSNP
rs986912596 2574 dbSNP
rs954155747 2579 dbSNP
rs1301190172 2590 dbSNP
rs1316138150 2594 dbSNP
rs1436445447 2595 dbSNP
rs1395519287 2600 dbSNP
rs576572502 2608 dbSNP
rs1375233985 2610 dbSNP
rs1236914208 2612 dbSNP
rs1280013123 2614 dbSNP
rs1312150701 2615 dbSNP
rs1208594570 2616 dbSNP
rs1252562185 2620 dbSNP
rs1452226555 2622 dbSNP
rs1177684265 2629 dbSNP
rs1235970598 2639 dbSNP
rs540058924 2640 dbSNP
rs1194001182 2642 dbSNP
rs1424146007 2645 dbSNP
rs995731480 2658 dbSNP
rs1172360453 2659 dbSNP
rs1474811158 2664 dbSNP
rs1466206913 2682 dbSNP
rs753105797 2683 dbSNP
rs1214357560 2684 dbSNP
rs556672516 2687 dbSNP
rs1486940318 2691 dbSNP
rs1443316405 2697 dbSNP
rs1275846661 2714 dbSNP
rs1367265794 2717 dbSNP
rs1217996449 2730 dbSNP
rs1004323233 2738 dbSNP
rs1281547444 2741 dbSNP
rs1210591685 2746 dbSNP
rs1346112932 2752 dbSNP
rs896227242 2761 dbSNP
rs1298042241 2762 dbSNP
rs767537284 2772 dbSNP
rs1056580134 2774 dbSNP
rs1001911147 2777 dbSNP
rs375770882 2779 dbSNP
rs1188279892 2782 dbSNP
rs905009897 2784 dbSNP
rs138387505 2789 dbSNP
rs946622349 2790 dbSNP
rs1398157789 2792 dbSNP
rs1463219235 2796 dbSNP
rs1312100810 2798 dbSNP
rs1349725310 2799 dbSNP
rs577579584 2803 dbSNP
rs1432650741 2804 dbSNP
rs1291184542 2808 dbSNP
rs1341652661 2827 dbSNP
rs1218506726 2828 dbSNP
rs1275790461 2831 dbSNP
rs1336211081 2844 dbSNP
rs59884381 2845 dbSNP
rs1288682293 2851 dbSNP
rs1170710313 2859 dbSNP
rs1217653084 2871 dbSNP
rs1053117163 2874 dbSNP
rs1191336451 2876 dbSNP
rs1421598122 2878 dbSNP
rs1473811616 2879 dbSNP
rs1164121981 2880 dbSNP
rs1413302534 2889 dbSNP
rs534211817 2895 dbSNP
rs1403997811 2926 dbSNP
rs1189412868 2928 dbSNP
rs1320713795 2936 dbSNP
rs572740666 2953 dbSNP
rs1296823846 2960 dbSNP
rs1258855736 2963 dbSNP
rs912567543 2967 dbSNP
rs1448086157 2976 dbSNP
rs761912801 2980 dbSNP
rs1283288627 2984 dbSNP
rs1484898476 2988 dbSNP
rs1353846053 2995 dbSNP
rs986860700 3001 dbSNP
rs1286483681 3008 dbSNP
rs548433222 3011 dbSNP
rs1214436526 3014 dbSNP
rs1259527759 3016 dbSNP
rs1307131579 3022 dbSNP
rs1271019737 3031 dbSNP
rs1236922832 3034 dbSNP
rs1471949263 3041 dbSNP
rs1160611310 3042 dbSNP
rs534244205 3044 dbSNP
rs1235187879 3045 dbSNP
rs1356114282 3049 dbSNP
rs1419466534 3055 dbSNP
rs1292627991 3062 dbSNP
rs62365876 3064 dbSNP
rs1415498681 3065 dbSNP
rs569751561 3072 dbSNP
rs549918310 3081 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cauUUCACUGUCUCAUAUCUgu 5'
             :||  | |||  ||:||  
Target 5' -uuGAGAAAAAGAAAAUGGAac 3'
 		1 - 21
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000303221.5 | 3UTR | UUGAGAAAAAGAAAAUGGAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
29 hsa-miR-4796-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT446014 VNN1 vanin 1 2 2
MIRT493828 FRS2 fibroblast growth factor receptor substrate 2 2 6
MIRT506324 ONECUT2 one cut homeobox 2 2 2
MIRT515488 PRKCD protein kinase C delta 2 4
MIRT515543 KRT222 keratin 222 2 4
MIRT518502 DEPTOR DEP domain containing MTOR interacting protein 2 6
MIRT519278 DDX55 DEAD-box helicase 55 2 2
MIRT528638 SENP6 SUMO1/sentrin specific peptidase 6 2 2
MIRT532130 NOL11 nucleolar protein 11 2 2
MIRT558240 EDA2R ectodysplasin A2 receptor 2 2
MIRT562293 GLO1 glyoxalase I 2 2
MIRT575346 Cacul1 CDK2 associated, cullin domain 1 2 2
MIRT610250 SLC35B4 solute carrier family 35 member B4 2 2
MIRT616752 SVOP SV2 related protein 2 2
MIRT627810 PTCHD1 patched domain containing 1 2 4
MIRT643062 CCDC149 coiled-coil domain containing 149 2 2
MIRT652031 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT658708 EMB embigin 2 2
MIRT687624 LRRC40 leucine rich repeat containing 40 2 2
MIRT692723 INPP5B inositol polyphosphate-5-phosphatase B 2 2
MIRT697508 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT702301 LAMP3 lysosomal associated membrane protein 3 2 2
MIRT718288 MINA ribosomal oxygenase 2 2 2
MIRT755767 BRCC3 BRCA1/BRCA2-containing complex subunit 3 5 1
MIRT755769 BARD1 BRCA1 associated RING domain 1 5 1
MIRT755770 ATM ATM serine/threonine kinase 5 1
MIRT755771 PARP14 poly(ADP-ribose) polymerase family member 14 5 1
MIRT755775 PARP2 poly(ADP-ribose) polymerase 2 5 1
MIRT755777 PARP11 poly(ADP-ribose) polymerase family member 11 5 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4796-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4796-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-4796-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)

Error report submission