pre-miRNA Information
pre-miRNA hsa-mir-3622b   
Genomic Coordinates chr8: 27701673 - 27701767
Description Homo sapiens miR-3622b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3622b-3p
Sequence 58| UCACCUGAGCUCCCGUGCCUG |78
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1232922758 2 dbSNP
rs530939348 5 dbSNP
rs1439657384 10 dbSNP
rs1157333896 12 dbSNP
rs66683138 14 dbSNP
rs1044808718 15 dbSNP
rs946438979 19 dbSNP
rs551845360 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol DNAJB5   
Synonyms Hsc40
Description DnaJ heat shock protein family (Hsp40) member B5
Transcript NM_001135004   
Other Transcripts NM_001135005 , NM_012266   
Expression
Putative miRNA Targets on DNAJB5
3'UTR of DNAJB5
(miRNA target sites are highlighted)
>DNAJB5|NM_001135004|3'UTR
   1 GCTCTGCCCCAGCCAGTCCAGAGCCTACCACAGCAATACCCCCAACACTCACTCCACTCAATGTGCACCCAGCTTGATGT
  81 CCACTGGACACTGGCAACTTTTTCTAAAATGCAAAAAAAAGCCACTGGTTTTCAGGAAAATGTTCCTGTCCCTGACCCCT
 161 TTTAGAGCTGGGCTGCCTGGGGGGAGTGGGAGGGAGGTGGGGAGAGCTAGCCCAGGCCAGGGGTCAATGTTCATGTCACT
 241 AGCTTTCAATCCAGTTTCCACTGCAGTGGCTGGAGAGTGACCTGAGTGCTACTTGAAGATATGTAGAGATTCCTTATCCA
 321 TGCCTGTACATAGCATGTCCTCCTCCCCTCAGCTTTGCTAATACCAGTCCCCTCCCTTCCCTTTGGCTTCCTGCTGTTGG
 401 GGGTGGAAAAGACTAGAAAGGACATTGCTTTCTCAGCCCCACCCCCAGGTCCACAGTGTCCAAGGTAATGGCACACATAT
 481 TCATGCACAAGAAGCACTCACCTAGAGCTGTCTGTGCCTCTCTGGGAGAAAGGAGAGAGGATAAGAAGGGAAAGTTCACA
 561 ACCTGTGAACAGGGACTTGAGCACGAGACACTTTTCATCTGGAGCAGGGGGGTGAGCTCCTCAGCAGCCTCCGTAACAGC
 641 TGCCCTGCCTACACCTGCAGAGCTGGAGGTTCTGTCCTCCCTGCTGCTCTCAGGAGTGTTCAAGGGTGGAGGGCAGGGAA
 721 TGGGGCCTGAGGTATTAAGGCTAAGAGGTGGGGGACAGGGCCCATCTACCAGCCTTCATCAGGAAGGGAAAGGGCTTTGG
 801 GGTCAGGTGGCAGCTATTCCCCACCAAGAGATTCAGGGTCACAGGTTTTTCCCCACACCTCTGAACTCAGGGCCTAGCCA
 881 CCCCCAAACTTCCAAATCCCACTTTTGTGATATGTGAAGCTACTCATTTCTTACCCTTGGAGGCTGTGTGGGGAATTTCC
 961 AGCCCTTTTATGCCTGTGTGATCCCACCCCACCCCCATAGTTGTATAAAGGTCATAGTGAAGAAGCTGGGGGAAGACTGC
1041 TTCAGCCAGATCCTGGGGTGGGGTCTTTAGGTTTTCTCACTTTGACAACCCCCGAATGTTTTTATAGTAGTTTTTTTGTA
1121 TTTTTTTGTAATGACAGTATTATGTAAAAAATAAAGTATTTTAAAAATATGGCAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' guCCGUGCCCUCGAGUCCACu 5'
            ||| : ||:| ||||||| 
Target 5' agGGCTTTGGGG-TCAGGTGg 3'
791 - 810 158.00 -23.90
2
miRNA  3' guCCGUGCCCUCG-AGUCCAcu 5'
            || ::|||: | |:||||  
Target 5' ctGGGGTGGGGTCTTTAGGTtt 3'
1053 - 1074 123.00 -16.90
3
miRNA  3' guCCGUGCCCUCGAGUCCacu 5'
            | ||| ||  :|||||   
Target 5' aaGCCACTGGTTTTCAGGaaa 3'
119 - 139 119.00 -14.52
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26973735 8 COSMIC
COSN30450408 10 COSMIC
COSN26973736 21 COSMIC
COSN1378300 121 COSMIC
COSN30711457 121 COSMIC
COSN30727328 143 COSMIC
COSN20076771 266 COSMIC
COSN6390030 268 COSMIC
COSN14769963 314 COSMIC
COSN14760468 472 COSMIC
COSN31513665 685 COSMIC
COSN28656328 748 COSMIC
COSN31553747 961 COSMIC
COSN31550275 1081 COSMIC
COSN26559928 1121 COSMIC
COSN31516825 1123 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs373116154 2 dbSNP
rs766874046 4 dbSNP
rs752033759 7 dbSNP
rs1226872177 9 dbSNP
rs1274318724 10 dbSNP
rs755598003 15 dbSNP
rs914891315 16 dbSNP
rs763519432 20 dbSNP
rs753416773 23 dbSNP
rs1299690790 25 dbSNP
rs908530318 26 dbSNP
rs756893350 28 dbSNP
rs1261875847 32 dbSNP
rs1451195683 34 dbSNP
rs778591083 36 dbSNP
rs745632299 37 dbSNP
rs368959542 40 dbSNP
rs1430383682 41 dbSNP
rs779994915 43 dbSNP
rs746936238 47 dbSNP
rs1348330966 55 dbSNP
rs534902052 59 dbSNP
rs770051452 62 dbSNP
rs921319578 66 dbSNP
rs1367480334 68 dbSNP
rs1265524389 72 dbSNP
rs910724675 73 dbSNP
rs770118094 74 dbSNP
rs1384257296 76 dbSNP
rs931820652 79 dbSNP
rs780509105 81 dbSNP
rs1288217633 82 dbSNP
rs1325571945 86 dbSNP
rs763366601 90 dbSNP
rs558001237 92 dbSNP
rs759958343 94 dbSNP
rs1263707876 96 dbSNP
rs768131436 98 dbSNP
rs1217751380 103 dbSNP
rs890404627 104 dbSNP
rs1465862475 106 dbSNP
rs759655154 113 dbSNP
rs776616566 113 dbSNP
rs1279638670 115 dbSNP
rs1227781891 117 dbSNP
rs1186193361 121 dbSNP
rs1247341146 127 dbSNP
rs1473110059 132 dbSNP
rs1009219402 137 dbSNP
rs1262240831 138 dbSNP
rs753327078 141 dbSNP
rs1398283796 142 dbSNP
rs1407426717 144 dbSNP
rs1411386666 149 dbSNP
rs756805139 150 dbSNP
rs1426306018 156 dbSNP
rs764830010 159 dbSNP
rs1390853614 160 dbSNP
rs1472613659 163 dbSNP
rs919539948 165 dbSNP
rs1320050442 166 dbSNP
rs1189654835 169 dbSNP
rs902852140 176 dbSNP
rs1461856144 179 dbSNP
rs750098617 180 dbSNP
rs143318274 181 dbSNP
rs929543750 182 dbSNP
rs1378936485 183 dbSNP
rs1195989827 185 dbSNP
rs765433413 185 dbSNP
rs758155863 187 dbSNP
rs887748429 188 dbSNP
rs1288577741 189 dbSNP
rs1330859428 195 dbSNP
rs1246266805 197 dbSNP
rs1252937339 198 dbSNP
rs1206253730 202 dbSNP
rs1382901278 203 dbSNP
rs1013009106 207 dbSNP
rs749499318 223 dbSNP
rs768950473 224 dbSNP
rs1402867797 226 dbSNP
rs1013062520 227 dbSNP
rs1405159519 234 dbSNP
rs750209558 247 dbSNP
rs1165230432 260 dbSNP
rs907280693 266 dbSNP
rs1024416528 269 dbSNP
rs774718576 271 dbSNP
rs1437796347 274 dbSNP
rs971655326 275 dbSNP
rs1182199507 283 dbSNP
rs760077992 285 dbSNP
rs1287233148 286 dbSNP
rs1224323945 291 dbSNP
rs771553658 305 dbSNP
rs983437198 313 dbSNP
rs885451 314 dbSNP
rs772251172 326 dbSNP
rs963045946 330 dbSNP
rs1238578103 333 dbSNP
rs773017644 337 dbSNP
rs1376102046 340 dbSNP
rs1266487369 347 dbSNP
rs974076511 360 dbSNP
rs1489672948 363 dbSNP
rs117178835 370 dbSNP
rs573659909 372 dbSNP
rs1325761527 375 dbSNP
rs760703973 376 dbSNP
rs542392877 378 dbSNP
rs559416357 384 dbSNP
rs1425609068 390 dbSNP
rs139255738 392 dbSNP
rs1465488489 395 dbSNP
rs141639960 397 dbSNP
rs911722798 401 dbSNP
rs1409985444 404 dbSNP
rs1177722497 406 dbSNP
rs944514411 409 dbSNP
rs1477566729 414 dbSNP
rs147075313 416 dbSNP
rs1201092269 422 dbSNP
rs1490424458 426 dbSNP
rs565138942 428 dbSNP
rs1262044195 441 dbSNP
rs1213770696 443 dbSNP
rs1318206115 447 dbSNP
rs181056420 448 dbSNP
rs1000289376 456 dbSNP
rs1343312506 457 dbSNP
rs1370075139 458 dbSNP
rs550193523 460 dbSNP
rs1405756796 461 dbSNP
rs776358163 465 dbSNP
rs41274871 472 dbSNP
rs1012611811 475 dbSNP
rs929576388 485 dbSNP
rs1024467475 488 dbSNP
rs1422770429 489 dbSNP
rs529370593 492 dbSNP
rs1480657037 493 dbSNP
rs1422382392 495 dbSNP
rs1004355534 509 dbSNP
rs1486556174 523 dbSNP
rs1016276769 528 dbSNP
rs1242266825 529 dbSNP
rs1436825081 533 dbSNP
rs962973099 541 dbSNP
rs544727559 543 dbSNP
rs974096665 551 dbSNP
rs1317701462 554 dbSNP
rs1276526100 560 dbSNP
rs1245985343 563 dbSNP
rs1028318254 565 dbSNP
rs1302380664 566 dbSNP
rs549173768 568 dbSNP
rs562406314 572 dbSNP
rs986883349 585 dbSNP
rs138273629 586 dbSNP
rs752363852 588 dbSNP
rs938729827 588 dbSNP
rs1056329906 592 dbSNP
rs1168094075 604 dbSNP
rs1429977437 605 dbSNP
rs1419585730 607 dbSNP
rs977260115 608 dbSNP
rs924548359 611 dbSNP
rs757836407 612 dbSNP
rs1054084951 613 dbSNP
rs1206862803 614 dbSNP
rs1361455582 628 dbSNP
rs1308246870 630 dbSNP
rs1009494721 632 dbSNP
rs1241451846 633 dbSNP
rs534842154 634 dbSNP
rs763729483 645 dbSNP
rs948351726 647 dbSNP
rs1258234716 654 dbSNP
rs1399241115 655 dbSNP
rs1045469760 659 dbSNP
rs1463352721 667 dbSNP
rs186297201 669 dbSNP
rs1158184777 672 dbSNP
rs1163642867 682 dbSNP
rs1412419837 692 dbSNP
rs1458565052 693 dbSNP
rs191540392 699 dbSNP
rs1017253772 709 dbSNP
rs1184718013 713 dbSNP
rs965787595 725 dbSNP
rs1236905238 726 dbSNP
rs1004810910 728 dbSNP
rs1265021751 732 dbSNP
rs1219720207 733 dbSNP
rs1015749079 741 dbSNP
rs9608 748 dbSNP
rs1375998289 751 dbSNP
rs1304828342 752 dbSNP
rs1304049047 753 dbSNP
rs1382049499 754 dbSNP
rs1390156065 756 dbSNP
rs1306847971 762 dbSNP
rs950845907 766 dbSNP
rs556901799 769 dbSNP
rs1292577282 777 dbSNP
rs1402760674 785 dbSNP
rs1230581630 793 dbSNP
rs1163614071 795 dbSNP
rs984920107 797 dbSNP
rs1418592479 811 dbSNP
rs1161927924 813 dbSNP
rs182779858 819 dbSNP
rs1056608128 822 dbSNP
rs1261519562 826 dbSNP
rs1420033494 827 dbSNP
rs187429377 833 dbSNP
rs909486543 870 dbSNP
rs995752864 879 dbSNP
rs1028538924 884 dbSNP
rs117965994 885 dbSNP
rs986772200 888 dbSNP
rs1020136550 889 dbSNP
rs1210958867 890 dbSNP
rs1215935370 914 dbSNP
rs966803589 915 dbSNP
rs1241176839 917 dbSNP
rs1479650433 926 dbSNP
rs1176563447 928 dbSNP
rs749630955 941 dbSNP
rs572986461 947 dbSNP
rs1473467244 952 dbSNP
rs924461423 954 dbSNP
rs1346955925 966 dbSNP
rs545212242 968 dbSNP
rs1196992174 976 dbSNP
rs1428216773 980 dbSNP
rs938761110 982 dbSNP
rs1052641 987 dbSNP
rs1414678569 988 dbSNP
rs1382211086 989 dbSNP
rs1177679687 990 dbSNP
rs935957199 994 dbSNP
rs1352279025 996 dbSNP
rs990029271 999 dbSNP
rs755406694 1001 dbSNP
rs1053159872 1002 dbSNP
rs891882813 1010 dbSNP
rs945226523 1029 dbSNP
rs867706133 1037 dbSNP
rs1412117246 1045 dbSNP
rs1281735239 1046 dbSNP
rs565119663 1054 dbSNP
rs1045354322 1062 dbSNP
rs11555365 1081 dbSNP
rs575585834 1086 dbSNP
rs906974502 1090 dbSNP
rs1206798610 1091 dbSNP
rs1017703295 1094 dbSNP
rs779263455 1095 dbSNP
rs1221385094 1105 dbSNP
rs1280931245 1109 dbSNP
rs748445572 1110 dbSNP
rs1283506584 1111 dbSNP
rs901485179 1111 dbSNP
rs997225907 1121 dbSNP
rs1324144497 1144 dbSNP
rs1037643519 1157 dbSNP
rs1382324090 1163 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_124A_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell miR-124 + A ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' guccgUGCCCUCGAGUCCAcu 5'
               | |||  :| :|||  
Target 5' -----AAGGGCUUUGGGGUc- 3'
1 - 15
Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset Chi_124A_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell miR-124 + A
Location of target site ENST00000545841.1 | 3UTR | AAGGGCUUUGGGGUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000545841.1 | 3UTR | GAAGGGAAAGGGCUUUGGGGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000545841.1 | 3UTR | GAAAGGGCUUUGGGGUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
THCA -0.218 0.32 -0.179 0.35 7 Click to see details
THCA -0.218 0.32 -0.179 0.35 7 Click to see details
THCA -0.218 0.32 -0.179 0.35 7 Click to see details
THCA -0.218 0.32 -0.179 0.35 7 Click to see details
THCA -0.218 0.32 -0.179 0.35 7 Click to see details
THCA -0.218 0.32 -0.179 0.35 7 Click to see details
102 hsa-miR-3622b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT076713 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT080212 PRKACB protein kinase cAMP-activated catalytic subunit beta 2 2
MIRT081398 GTPBP3 GTP binding protein 3, mitochondrial 2 2
MIRT107158 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT254071 BACH1 BTB domain and CNC homolog 1 2 2
MIRT409790 FOXO3 forkhead box O3 2 2
MIRT448679 MAPK9 mitogen-activated protein kinase 9 2 2
MIRT450206 ABHD15 abhydrolase domain containing 15 2 2
MIRT486621 PDK3 pyruvate dehydrogenase kinase 3 2 2
MIRT489267 TTLL1 tubulin tyrosine ligase like 1 2 2
MIRT493117 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 4
MIRT494570 BAK1 BCL2 antagonist/killer 1 2 2
MIRT497395 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT504900 CCDC86 coiled-coil domain containing 86 2 2
MIRT505192 USP46 ubiquitin specific peptidase 46 2 4
MIRT506522 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 6
MIRT508162 ABCC5 ATP binding cassette subfamily C member 5 2 8
MIRT508545 PARVG parvin gamma 2 4
MIRT509850 BIRC5 baculoviral IAP repeat containing 5 2 6
MIRT510088 PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2 8
MIRT512094 CRK CRK proto-oncogene, adaptor protein 2 4
MIRT515381 RPL7 ribosomal protein L7 2 2
MIRT519176 SCO1 SCO1, cytochrome c oxidase assembly protein 2 2
MIRT519964 ZCCHC8 zinc finger CCHC-type containing 8 2 2
MIRT522292 NKAP NFKB activating protein 2 2
MIRT523160 HMGB2 high mobility group box 2 2 4
MIRT525314 FANCA Fanconi anemia complementation group A 2 2
MIRT528194 PLEKHM2 pleckstrin homology and RUN domain containing M2 2 2
MIRT532885 ZNF451 zinc finger protein 451 2 2
MIRT538209 CYR61 cysteine rich angiogenic inducer 61 2 2
MIRT539497 ACTN4 actinin alpha 4 2 2
MIRT554600 RRAGC Ras related GTP binding C 2 2
MIRT562444 DCTN6 dynactin subunit 6 2 2
MIRT562748 AOC3 amine oxidase, copper containing 3 2 2
MIRT565798 SEC14L5 SEC14 like lipid binding 5 2 2
MIRT565838 SCML2 Scm polycomb group protein like 2 2 2
MIRT566072 RCC2 regulator of chromosome condensation 2 2 2
MIRT566104 RBPJ recombination signal binding protein for immunoglobulin kappa J region 2 2
MIRT572407 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT576198 Vsig2 V-set and immunoglobulin domain containing 2 2 2
MIRT576313 Acbd7 acyl-Coenzyme A binding domain containing 7 2 2
MIRT576651 Mill2 MHC I like leukocyte 2 1 1
MIRT576859 Socs6 suppressor of cytokine signaling 6 2 2
MIRT606819 BICD2 BICD cargo adaptor 2 2 2
MIRT610738 NUDT16 nudix hydrolase 16 2 4
MIRT614798 RORA RAR related orphan receptor A 2 2
MIRT619006 NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 2 2
MIRT619420 NOS1AP nitric oxide synthase 1 adaptor protein 2 2
MIRT620405 MYO1H myosin IH 2 2
MIRT624869 ABHD13 abhydrolase domain containing 13 2 2
MIRT633527 ZFP30 ZFP30 zinc finger protein 2 2
MIRT633927 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT636611 CLIC5 chloride intracellular channel 5 2 2
MIRT640616 MIOX myo-inositol oxygenase 2 2
MIRT642605 C14orf180 chromosome 14 open reading frame 180 2 2
MIRT644624 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT655113 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT658976 DNAJB5 DnaJ heat shock protein family (Hsp40) member B5 2 4
MIRT661495 CHMP1B charged multivesicular body protein 1B 2 2
MIRT662996 TMEM59 transmembrane protein 59 2 2
MIRT663075 SFR1 SWI5 dependent homologous recombination repair protein 1 2 2
MIRT665405 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT666106 SSR1 signal sequence receptor subunit 1 2 2
MIRT669562 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT670070 ZNF783 zinc finger family member 783 2 2
MIRT671192 ZNF891 zinc finger protein 891 2 2
MIRT675361 KLHL26 kelch like family member 26 2 2
MIRT678857 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT679443 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT684163 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT684543 ZNF460 zinc finger protein 460 2 2
MIRT684674 SLC2A11 solute carrier family 2 member 11 2 2
MIRT684971 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT686006 NEK4 NIMA related kinase 4 2 2
MIRT687758 KIAA1328 KIAA1328 2 2
MIRT688961 ATXN3 ataxin 3 2 2
MIRT689409 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT690001 MMP17 matrix metallopeptidase 17 2 2
MIRT690165 ELP3 elongator acetyltransferase complex subunit 3 2 2
MIRT690202 C5orf45 MRN complex interacting protein 2 2
MIRT690477 ZNF33A zinc finger protein 33A 2 2
MIRT690566 MICA MHC class I polypeptide-related sequence A 2 2
MIRT692160 C10orf111 chromosome 10 open reading frame 111 2 2
MIRT693430 PLGLB2 plasminogen-like B2 2 2
MIRT693547 ZNF708 zinc finger protein 708 2 2
MIRT693697 PLGLB1 plasminogen-like B1 2 2
MIRT695006 HSPA6 heat shock protein family A (Hsp70) member 6 2 2
MIRT698525 TFRC transferrin receptor 2 2
MIRT699574 SIKE1 suppressor of IKBKE 1 2 2
MIRT703446 FYTTD1 forty-two-three domain containing 1 2 2
MIRT704397 CTSS cathepsin S 2 2
MIRT704485 CPT1A carnitine palmitoyltransferase 1A 2 2
MIRT709822 STPG1 sperm tail PG-rich repeat containing 1 2 2
MIRT710859 COQ7 coenzyme Q7, hydroxylase 2 2
MIRT711893 INSIG2 insulin induced gene 2 2 2
MIRT713796 CPLX2 complexin 2 2 2
MIRT718800 C1GALT1C1 C1GALT1 specific chaperone 1 2 2
MIRT719501 SEC24B SEC24 homolog B, COPII coat complex component 2 2
MIRT719722 PDE6B phosphodiesterase 6B 2 2
MIRT722204 URM1 ubiquitin related modifier 1 2 2
MIRT723523 CLPTM1L CLPTM1 like 2 2
MIRT725471 GRAP2 GRB2-related adaptor protein 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3622b-3p Platinum 23939 sensitive tissue
hsa-miR-3622b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3622b-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-3622b-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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