miRTarBase - #MIRT664595


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pre-miRNA Information
pre-miRNA hsa-mir-4793   
Genomic Coordinates chr3: 48644194 - 48644280
Description Homo sapiens miR-4793 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4793-3p
Sequence 58| UCUGCACUGUGAGUUGGCUGGCU |80
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM5899925 14 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs779602935 6 dbSNP
rs757908486 7 dbSNP
rs1422853760 15 dbSNP
rs377721296 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol HSD17B12   
Synonyms KAR, SDR12C1
Description hydroxysteroid 17-beta dehydrogenase 12
Transcript NM_016142   
Expression
Putative miRNA Targets on HSD17B12
3'UTR of HSD17B12
(miRNA target sites are highlighted)		 
>HSD17B12|NM_016142|3'UTR
   1 GCATTGATAACTGCATTGTAACTTGGCCAGATGCTCCAGCATATGCACGTTCACTGCAAAGCACCCTACTGGTTTTGAAA
  81 ATCTGACCTTGTCATTTCAATAGTTATTAACATGACTAAATATTATCTTAATTAAGAGGAAAATAGAAGTTGCTTTTAGG
 161 GGTTTCTGACATATATTCTGGATACTATCCGAGGTAATTTTGAAGTTTAATATAAATGCTCATATCAAATGAATATAGAA
 241 CTAATATTGTCGGGAACACCTAATAGAAAGGAATACTATTATAGCAAATCACAGAATGATAGACTCAAGCATAAAACTTG
 321 GCAGTTTTATCTGCTTCAAAATGCCATTGATCATTATTCCTGTATTTTCTCTGAAACTGATTATAAAAACCAATGTCCAG
 401 CTACTCTTTTGTTTTTGACACTTGAAGAAATGGAGATCGATTTGATTTGTTTATAAGCAGACACACTGCAATTTACAAAG
 481 ATCTCTTTACGGTTTTATAAAATTATCTTCCAGTTTGTACATTTATATGGAATTGTTCTTTATCAAGGGTAGCTAATGAC
 561 ATGAAAATAATTGTGAAATATGGAATTATTTCTGACACATGAAGCCCACTAAACTATGCTTTCTTATAATGCATATTTCT
 641 TCTCAGTTTAAATGTATGTAAATATCGAAGCTATATGGTATGATTTATAAAGATAAATGGGCCAAAGTGTACATTGAGAC
 721 TGGCAGCCATCTATGGTACCACTGAAACCCTGACCCAGAAAAGTGGCTTGCTTGGACACCCAGCTGCCTTTGTTTCTGCA
 801 TTAAACCAATATTGATCACACATATGACACAGGCTAGTCCTATAAAAGTAATGACTTCATAGAAATGGCATTATAATTTT
 881 TAAGTTGATACTCTACAGGTAGCTATTGATATAATTAGTTTTAATAAAACATGCTGCAACCATGGTATACAACAAAAATA
 961 CATTTCTTTGGTGATTGAAATTAAGGCCGTATTTACAATGACTTAATATAAGACTGACTTTTATCCTGCTTCATAACTTG
1041 TATGGAGAACTCACCAAGAAAGAATTCAATACTGTGAAATATGCAGCAAGAAGATTGGTCTTTACCTAGGCTGTGTTTCC
1121 TAAGCTCTGAGTTTTCAGCACCAGTAGATTTGTATTAAAAGAAAAAAAAATGGGGCCTTAGCTTCTGGCTTTTAATTTTG
1201 CCAGCTAAGGACATAAAACAAAAATAAACAAACAAAAACAAATAGCCATCTGCTATCAGCATCATTATGTAAAAGAAAAT
1281 ATATTTTAGCCCCTAAAATTAGGAAGAATGTAATCTCAGAATAAAGGTTGTCATTTAAGTTGAATAAATATATAGCTTTA
1361 TGAAAAACACAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucggUCGGUUGA----GUGUCACGUcu 5'
              || :|| |    || ||||:|  
Target 5' ataaAGATAAATGGGCCAAAGTGTAca 3'
 687 - 713 117.00 -9.20
2 
miRNA  3' ucGGU-CGGUUGAGUGUCACGUcu 5'
            |:| ||:  ||:|:| ||||  
Target 5' aaCTATGCTTTCTTATAATGCAta 3'
 612 - 635 113.00 -12.60
3 
miRNA  3' ucGGUCGGUUGAGU----GUCACGUcu 5'
            |||||  |: ||    || ||||  
Target 5' ctCCAGCATATGCACGTTCACTGCAaa 3'
 34 - 60 111.00 -13.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30145670 78 COSMIC
COSN30171537 78 COSMIC
COSN31554819 111 COSMIC
COSN505734 163 COSMIC
COSN30130079 303 COSMIC
COSN17181619 325 COSMIC
COSN18976139 413 COSMIC
COSN20108166 413 COSMIC
COSN32062544 439 COSMIC
COSN30172050 481 COSMIC
COSN31539157 491 COSMIC
COSN30543462 553 COSMIC
COSN15804837 720 COSMIC
COSN17290300 1251 COSMIC
COSN26157499 1254 COSMIC
COSN1534902 1344 COSMIC
rs1061810 1137 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs750830046 4 dbSNP
rs753804701 13 dbSNP
rs573019251 14 dbSNP
rs11037683 16 dbSNP
rs751079549 17 dbSNP
rs754668712 25 dbSNP
rs780805754 26 dbSNP
rs1171800028 31 dbSNP
rs11037684 32 dbSNP
rs769508734 42 dbSNP
rs182511068 49 dbSNP
rs187110642 50 dbSNP
rs751153565 53 dbSNP
rs1480383833 56 dbSNP
rs753519790 57 dbSNP
rs1440988974 61 dbSNP
rs563672988 62 dbSNP
rs1380690691 67 dbSNP
rs1226060321 71 dbSNP
rs1245009693 83 dbSNP
rs191217025 85 dbSNP
rs1383214535 91 dbSNP
rs755397213 94 dbSNP
rs552336983 102 dbSNP
rs549013875 104 dbSNP
rs1372063192 112 dbSNP
rs1298255732 117 dbSNP
rs1431042668 122 dbSNP
rs887022493 126 dbSNP
rs1163471985 145 dbSNP
rs781645581 146 dbSNP
rs1272179776 148 dbSNP
rs1016997081 152 dbSNP
rs560951749 162 dbSNP
rs1418731319 164 dbSNP
rs763291488 171 dbSNP
rs1251446235 173 dbSNP
rs898175913 173 dbSNP
rs996573120 191 dbSNP
rs1289552102 192 dbSNP
rs1221619570 208 dbSNP
rs1028077572 214 dbSNP
rs111650837 221 dbSNP
rs1266983141 227 dbSNP
rs1236528321 233 dbSNP
rs748676184 239 dbSNP
rs1204082530 241 dbSNP
rs987364242 251 dbSNP
rs1031880757 252 dbSNP
rs528727998 253 dbSNP
rs1473902429 260 dbSNP
rs990447062 264 dbSNP
rs1180154284 265 dbSNP
rs528539782 266 dbSNP
rs755199252 271 dbSNP
rs1384715942 279 dbSNP
rs1450618389 283 dbSNP
rs1453440998 283 dbSNP
rs948741876 287 dbSNP
rs541334060 297 dbSNP
rs980117950 307 dbSNP
rs938802722 308 dbSNP
rs182661482 318 dbSNP
rs1335292071 319 dbSNP
rs778419070 335 dbSNP
rs1360464312 338 dbSNP
rs1203186701 340 dbSNP
rs1485403944 344 dbSNP
rs1268424887 347 dbSNP
rs1229840663 365 dbSNP
rs551633681 391 dbSNP
rs1445396914 395 dbSNP
rs1282099385 405 dbSNP
rs146635402 407 dbSNP
rs367793452 407 dbSNP
rs768994653 407 dbSNP
rs939902270 410 dbSNP
rs1038307637 411 dbSNP
rs898122097 414 dbSNP
rs996520793 425 dbSNP
rs1322869974 427 dbSNP
rs1468425732 432 dbSNP
rs1028023687 436 dbSNP
rs1230477469 437 dbSNP
rs749441064 440 dbSNP
rs1379340278 451 dbSNP
rs1190909916 460 dbSNP
rs1446272205 461 dbSNP
rs1248407318 464 dbSNP
rs1210293316 472 dbSNP
rs570535682 479 dbSNP
rs1295397174 491 dbSNP
rs1338487393 492 dbSNP
rs1200570038 504 dbSNP
rs762691130 506 dbSNP
rs187660681 543 dbSNP
rs1008003028 546 dbSNP
rs1366456277 549 dbSNP
rs550582224 563 dbSNP
rs1450834000 564 dbSNP
rs1487372611 582 dbSNP
rs569212595 590 dbSNP
rs1335055681 594 dbSNP
rs956247733 599 dbSNP
rs1012219479 610 dbSNP
rs193205496 615 dbSNP
rs1242582030 617 dbSNP
rs1390653847 627 dbSNP
rs1270527990 653 dbSNP
rs1465454459 654 dbSNP
rs1191042468 655 dbSNP
rs1388796682 658 dbSNP
rs1475376278 659 dbSNP
rs1190302880 668 dbSNP
rs969997315 674 dbSNP
rs980065321 675 dbSNP
rs752905430 677 dbSNP
rs1270264284 680 dbSNP
rs928663030 686 dbSNP
rs1343513877 687 dbSNP
rs1277333312 698 dbSNP
rs960387165 702 dbSNP
rs759637391 710 dbSNP
rs1285067630 718 dbSNP
rs1450462614 730 dbSNP
rs983567975 732 dbSNP
rs1328289271 733 dbSNP
rs1430436738 734 dbSNP
rs908347374 734 dbSNP
rs1170385492 738 dbSNP
rs1422564497 739 dbSNP
rs1384361148 752 dbSNP
rs757553876 752 dbSNP
rs1473576610 753 dbSNP
rs1038659465 755 dbSNP
rs554557084 759 dbSNP
rs1483074005 761 dbSNP
rs1254644303 762 dbSNP
rs566482460 767 dbSNP
rs908517665 771 dbSNP
rs533617306 772 dbSNP
rs1359259239 782 dbSNP
rs932592520 783 dbSNP
rs1230333503 786 dbSNP
rs1348842664 786 dbSNP
rs1279151310 789 dbSNP
rs1410562814 804 dbSNP
rs1049407709 810 dbSNP
rs558641381 813 dbSNP
rs1309835820 815 dbSNP
rs1403019569 822 dbSNP
rs1325746163 840 dbSNP
rs1437137607 844 dbSNP
rs1165232148 852 dbSNP
rs890826285 852 dbSNP
rs758525090 853 dbSNP
rs1405380898 857 dbSNP
rs1157916228 861 dbSNP
rs1472666264 868 dbSNP
rs1413527453 871 dbSNP
rs970956242 885 dbSNP
rs1052893358 886 dbSNP
rs891921395 907 dbSNP
rs1221907205 910 dbSNP
rs1224283421 919 dbSNP
rs1011755670 920 dbSNP
rs578099036 929 dbSNP
rs1229226253 931 dbSNP
rs1331389481 932 dbSNP
rs545624373 943 dbSNP
rs1259778429 947 dbSNP
rs1446877168 948 dbSNP
rs1021782625 975 dbSNP
rs1343191667 976 dbSNP
rs557230073 989 dbSNP
rs549385406 990 dbSNP
rs1001770246 997 dbSNP
rs1413638814 1009 dbSNP
rs1173660644 1019 dbSNP
rs11555763 1020 dbSNP
rs1426530811 1032 dbSNP
rs11555765 1041 dbSNP
rs542925576 1042 dbSNP
rs1241890452 1058 dbSNP
rs1209683002 1060 dbSNP
rs1198217945 1066 dbSNP
rs1412172612 1070 dbSNP
rs1261445460 1083 dbSNP
rs1203148829 1092 dbSNP
rs1312816205 1095 dbSNP
rs960085110 1096 dbSNP
rs983901267 1101 dbSNP
rs1359696025 1113 dbSNP
rs1061810 1137 dbSNP
rs144353338 1138 dbSNP
rs1182285910 1145 dbSNP
rs555290841 1148 dbSNP
rs1334247653 1153 dbSNP
rs1465148428 1155 dbSNP
rs1405855068 1157 dbSNP
rs1359218565 1158 dbSNP
rs919779315 1162 dbSNP
rs973896924 1162 dbSNP
rs1189640029 1175 dbSNP
rs1451676063 1194 dbSNP
rs1325526017 1196 dbSNP
rs1181476088 1197 dbSNP
rs1483653303 1210 dbSNP
rs932545345 1212 dbSNP
rs1329125431 1221 dbSNP
rs1404046184 1226 dbSNP
rs1305715349 1227 dbSNP
rs1288756024 1231 dbSNP
rs1228915821 1233 dbSNP
rs1367062541 1234 dbSNP
rs540343616 1235 dbSNP
rs565415301 1249 dbSNP
rs1395083962 1255 dbSNP
rs1230486111 1261 dbSNP
rs1259015745 1265 dbSNP
rs1379364917 1269 dbSNP
rs1304096448 1275 dbSNP
rs1350095584 1294 dbSNP
rs1210950938 1302 dbSNP
rs1292708224 1328 dbSNP
rs1432069202 1340 dbSNP
rs1383759719 1342 dbSNP
rs1164437699 1343 dbSNP
rs1424628959 1343 dbSNP
rs1490006034 1351 dbSNP
rs1258469132 1352 dbSNP
rs1175585672 1353 dbSNP
rs1482750389 1361 dbSNP
rs944381882 1364 dbSNP
rs1205764169 1365 dbSNP
rs1253019421 1368 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucgguCGGUUGAGUGUCACGUCu 5'
               ||||:  :: ||||||| 
Target 5' ---ucGCCAGGCUGGAGUGCAGu 3'
 		1 - 20
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucgGUCGGUUGAGUGUCACGUCu 5'
             || | |:  :: ||||||| 
Target 5' ---CACCGAGGCUGGAGUGCAGu 3'
 		1 - 20
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000278353.4 | 3UTR | UCGCCAGGCUGGAGUGCAGUGGCACGAUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000278353.4 | 3UTR | CACCGAGGCUGGAGUGCAGUGGCGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
296 hsa-miR-4793-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT092332 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 6
MIRT131237 ATG2A autophagy related 2A 2 2
MIRT145926 ANKFY1 ankyrin repeat and FYVE domain containing 1 2 2
MIRT206559 SOCS5 suppressor of cytokine signaling 5 2 8
MIRT226455 TP53INP1 tumor protein p53 inducible nuclear protein 1 2 2
MIRT337662 ZNF695 zinc finger protein 695 2 2
MIRT405828 SIX4 SIX homeobox 4 2 2
MIRT455113 RILPL1 Rab interacting lysosomal protein like 1 2 2
MIRT456756 TMEM239 transmembrane protein 239 2 4
MIRT457974 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT458173 LYRM4 LYR motif containing 4 2 4
MIRT458245 SLC9A7 solute carrier family 9 member A7 2 2
MIRT466145 TMEM120B transmembrane protein 120B 2 2
MIRT474981 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT475601 HMGB2 high mobility group box 2 2 4
MIRT480759 BMP3 bone morphogenetic protein 3 2 4
MIRT481156 AVL9 AVL9 cell migration associated 2 2
MIRT482155 AK2 adenylate kinase 2 2 2
MIRT488386 VAV3 vav guanine nucleotide exchange factor 3 2 6
MIRT496575 KIF18B kinesin family member 18B 2 2
MIRT498411 TXNDC16 thioredoxin domain containing 16 2 4
MIRT504547 ZNF417 zinc finger protein 417 2 6
MIRT505417 TCF7L2 transcription factor 7 like 2 2 2
MIRT509349 ALDH9A1 aldehyde dehydrogenase 9 family member A1 2 6
MIRT512164 CD164 CD164 molecule 2 6
MIRT517238 PRIM1 DNA primase subunit 1 2 2
MIRT518671 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 2
MIRT519298 MLH1 mutL homolog 1 2 2
MIRT523662 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 2
MIRT525452 GPATCH2L G-patch domain containing 2 like 2 2
MIRT539847 ZNF766 zinc finger protein 766 2 2
MIRT540076 SSH3 slingshot protein phosphatase 3 2 2
MIRT540320 PIGR polymeric immunoglobulin receptor 2 2
MIRT540548 MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 2 2
MIRT540759 UTP6 UTP6, small subunit processome component 2 2
MIRT541545 HIATL2 major facilitator superfamily domain containing 14C 2 2
MIRT541553 SLC35E1 solute carrier family 35 member E1 2 2
MIRT541666 ATP8B3 ATPase phospholipid transporting 8B3 2 4
MIRT541722 TFDP2 transcription factor Dp-2 2 2
MIRT541800 DUSP28 dual specificity phosphatase 28 2 2
MIRT541816 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT541907 VWA7 von Willebrand factor A domain containing 7 2 2
MIRT542154 UGDH UDP-glucose 6-dehydrogenase 2 2
MIRT542207 C14orf142 GON7, KEOPS complex subunit homolog 2 2
MIRT542233 FUT9 fucosyltransferase 9 2 2
MIRT542320 SERPING1 serpin family G member 1 2 2
MIRT542369 PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 2
MIRT542476 APOC3 apolipoprotein C3 2 2
MIRT542641 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT542660 TAF11 TATA-box binding protein associated factor 11 2 2
MIRT542749 PRRG4 proline rich and Gla domain 4 2 4
MIRT542789 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT545442 FGFRL1 fibroblast growth factor receptor like 1 2 2
MIRT546206 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT552270 RAB3D RAB3D, member RAS oncogene family 2 2
MIRT552655 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT554134 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT556795 KIAA1958 KIAA1958 2 2
MIRT564762 ZHX3 zinc fingers and homeoboxes 3 2 2
MIRT569428 STX7 syntaxin 7 2 2
MIRT573245 ZBTB46 zinc finger and BTB domain containing 46 2 2
MIRT607390 LANCL3 LanC like 3 2 2
MIRT607430 NOTCH2NL notch 2 N-terminal like 2 2
MIRT607452 ZNF543 zinc finger protein 543 2 2
MIRT607580 TANGO2 transport and golgi organization 2 homolog 2 2
MIRT607748 ANGPT4 angiopoietin 4 2 2
MIRT607907 SPRYD4 SPRY domain containing 4 2 2
MIRT608703 GMPR guanosine monophosphate reductase 2 2
MIRT612127 NDUFA10 NADH:ubiquinone oxidoreductase subunit A10 2 2
MIRT612786 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 4
MIRT616692 LPL lipoprotein lipase 2 2
MIRT617045 ZNF610 zinc finger protein 610 2 2
MIRT617091 ZNF43 zinc finger protein 43 2 2
MIRT617314 MBOAT1 membrane bound O-acyltransferase domain containing 1 2 2
MIRT617355 MELK maternal embryonic leucine zipper kinase 2 2
MIRT617486 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT617579 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT617669 RSRC1 arginine and serine rich coiled-coil 1 2 2
MIRT617722 TRAPPC2 trafficking protein particle complex 2 2 4
MIRT617893 PTCHD3 patched domain containing 3 2 2
MIRT617982 ZNF234 zinc finger protein 234 2 4
MIRT618434 MYLK3 myosin light chain kinase 3 2 4
MIRT618732 HIST1H2AH histone cluster 1 H2A family member h 2 2
MIRT619045 CASS4 Cas scaffolding protein family member 4 2 2
MIRT619573 ATAT1 alpha tubulin acetyltransferase 1 2 4
MIRT619671 CYP1A2 cytochrome P450 family 1 subfamily A member 2 2 2
MIRT619887 ABHD17B abhydrolase domain containing 17B 2 2
MIRT620519 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 4
MIRT620535 AVPR1A arginine vasopressin receptor 1A 2 2
MIRT620996 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT621304 YIPF4 Yip1 domain family member 4 2 2
MIRT622086 SRPX2 sushi repeat containing protein, X-linked 2 2 2
MIRT622168 SMYD1 SET and MYND domain containing 1 2 2
MIRT622543 PXMP4 peroxisomal membrane protein 4 2 2
MIRT622761 PGM3 phosphoglucomutase 3 2 2
MIRT622885 PDCL3 phosducin like 3 2 4
MIRT623130 NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 2 2
MIRT624840 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2 2
MIRT625047 MBD3 methyl-CpG binding domain protein 3 2 2
MIRT625059 ZNF556 zinc finger protein 556 2 2
MIRT625508 PPAPDC1A phospholipid phosphatase 4 2 2
MIRT625573 ANKRD42 ankyrin repeat domain 42 2 2
MIRT626133 SNRNP48 small nuclear ribonucleoprotein U11/U12 subunit 48 2 2
MIRT626327 LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2 2
MIRT626765 CDC14B cell division cycle 14B 2 2
MIRT626798 CSE1L chromosome segregation 1 like 2 2
MIRT627212 ZC3H12B zinc finger CCCH-type containing 12B 2 2
MIRT627225 ZBTB8B zinc finger and BTB domain containing 8B 2 4
MIRT627256 XKR4 XK related 4 2 2
MIRT628190 GATSL2 cytosolic arginine sensor for mTORC1 subunit 2 2 2
MIRT628466 AHSA2 activator of HSP90 ATPase homolog 2 2 2
MIRT628627 CCT4 chaperonin containing TCP1 subunit 4 2 2
MIRT629040 KLLN killin, p53-regulated DNA replication inhibitor 2 2
MIRT630847 ACACB acetyl-CoA carboxylase beta 2 2
MIRT631721 RNASEH2B ribonuclease H2 subunit B 2 2
MIRT632264 USP1 ubiquitin specific peptidase 1 2 4
MIRT632571 POLQ DNA polymerase theta 2 2
MIRT633992 SLC35E2 solute carrier family 35 member E2 2 2
MIRT635211 ZNF286A zinc finger protein 286A 2 4
MIRT635249 ELOVL6 ELOVL fatty acid elongase 6 2 4
MIRT635261 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT635283 GK5 glycerol kinase 5 (putative) 2 2
MIRT635663 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT636251 SEC63 SEC63 homolog, protein translocation regulator 2 2
MIRT636564 EPB41 erythrocyte membrane protein band 4.1 2 2
MIRT636814 TBC1D24 TBC1 domain family member 24 2 2
MIRT637358 ZNF460 zinc finger protein 460 2 2
MIRT637473 DEFB105B defensin beta 105B 2 4
MIRT637505 DEFB105A defensin beta 105A 2 4
MIRT637861 SC5D sterol-C5-desaturase 2 2
MIRT638080 ZNF652 zinc finger protein 652 2 2
MIRT638096 ZBTB8A zinc finger and BTB domain containing 8A 2 2
MIRT638174 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT638201 TAF13 TATA-box binding protein associated factor 13 2 2
MIRT638278 SH2B3 SH2B adaptor protein 3 2 2
MIRT638714 FUT11 fucosyltransferase 11 2 2
MIRT638852 CLMP CXADR like membrane protein 2 2
MIRT639815 TMED8 transmembrane p24 trafficking protein family member 8 2 2
MIRT640879 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT640937 FAM129A family with sequence similarity 129 member A 2 2
MIRT640971 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT641642 GNAZ G protein subunit alpha z 2 2
MIRT641931 SLC25A16 solute carrier family 25 member 16 2 2
MIRT642136 CRY2 cryptochrome circadian clock 2 2 2
MIRT643199 JAK3 Janus kinase 3 2 2
MIRT643256 ZNF566 zinc finger protein 566 2 2
MIRT643378 TRIM16L tripartite motif containing 16 like 2 2
MIRT643683 AMER3 APC membrane recruitment protein 3 2 2
MIRT643728 MCMDC2 minichromosome maintenance domain containing 2 2 2
MIRT643949 CCDC141 coiled-coil domain containing 141 2 2
MIRT644915 SERF1B small EDRK-rich factor 1B 2 2
MIRT645163 NOL9 nucleolar protein 9 2 2
MIRT645547 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 2
MIRT645550 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 2
MIRT645572 TACR2 tachykinin receptor 2 2 2
MIRT646697 SERF1A small EDRK-rich factor 1A 2 2
MIRT647806 FRMD8 FERM domain containing 8 2 2
MIRT647903 CIRH1A UTP4, small subunit processome component 2 2
MIRT648978 ACAD8 acyl-CoA dehydrogenase family member 8 2 2
MIRT649907 SLFN12L schlafen family member 12 like 2 2
MIRT650224 SIGLEC9 sialic acid binding Ig like lectin 9 2 4
MIRT651880 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT651935 UBN1 ubinuclein 1 2 2
MIRT652839 TACO1 translational activator of cytochrome c oxidase I 2 2
MIRT652994 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT654800 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT655591 OTUD7B OTU deubiquitinase 7B 2 2
MIRT658760 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT659358 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT660717 AMER1 APC membrane recruitment protein 1 2 2
MIRT660737 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT661088 TMEM145 transmembrane protein 145 2 2
MIRT661176 S1PR2 sphingosine-1-phosphate receptor 2 2 2
MIRT662005 ZNF445 zinc finger protein 445 2 2
MIRT662178 KIAA1210 KIAA1210 2 2
MIRT662270 OR51E2 olfactory receptor family 51 subfamily E member 2 2 2
MIRT663046 SLC16A4 solute carrier family 16 member 4 2 2
MIRT663476 POFUT2 protein O-fucosyltransferase 2 2 2
MIRT664039 RPL27A ribosomal protein L27a 2 2
MIRT664096 ZDHHC24 zinc finger DHHC-type containing 24 2 2
MIRT664109 FUT1 fucosyltransferase 1 (H blood group) 2 2
MIRT664317 CD209 CD209 molecule 2 2
MIRT664455 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT664595 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 4
MIRT664694 DBF4 DBF4 zinc finger 2 2
MIRT665162 SF3A1 splicing factor 3a subunit 1 2 2
MIRT665214 RBM22 RNA binding motif protein 22 2 2
MIRT665254 ZNF286B zinc finger protein 286B 2 2
MIRT665268 ZFP69B ZFP69 zinc finger protein B 2 2
MIRT665606 TTC39A tetratricopeptide repeat domain 39A 2 2
MIRT665830 TIMELESS timeless circadian clock 2 2
MIRT666201 SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 2 2
MIRT666546 RNF115 ring finger protein 115 2 2
MIRT666602 REEP3 receptor accessory protein 3 2 2
MIRT666862 POU2F3 POU class 2 homeobox 3 2 4
MIRT666886 POLA2 DNA polymerase alpha 2, accessory subunit 2 2
MIRT667158 NRXN3 neurexin 3 2 2
MIRT667252 NEK9 NIMA related kinase 9 2 2
MIRT667419 MFSD2A major facilitator superfamily domain containing 2A 2 2
MIRT667434 METTL8 methyltransferase like 8 2 2
MIRT668023 HAUS3 HAUS augmin like complex subunit 3 2 2
MIRT668062 GPR75 G protein-coupled receptor 75 2 2
MIRT668070 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT668607 EHD4 EH domain containing 4 2 4
MIRT668694 DNAL1 dynein axonemal light chain 1 2 2
MIRT668782 DAAM1 dishevelled associated activator of morphogenesis 1 2 2
MIRT669037 CHEK1 checkpoint kinase 1 2 2
MIRT669044 CHAF1B chromatin assembly factor 1 subunit B 2 4
MIRT669156 CCNG1 cyclin G1 2 2
MIRT670090 ABCF3 ATP binding cassette subfamily F member 3 2 4
MIRT670206 SLC24A4 solute carrier family 24 member 4 2 2
MIRT672488 FUS FUS RNA binding protein 2 2
MIRT673830 SLC11A2 solute carrier family 11 member 2 2 2
MIRT675481 VEGFC vascular endothelial growth factor C 2 2
MIRT675634 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2 2
MIRT677913 HIST1H2BN histone cluster 1 H2B family member n 2 2
MIRT678420 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678626 OLFML2A olfactomedin like 2A 2 2
MIRT678791 NUPL2 nucleoporin like 2 2 2
MIRT679561 LIN9 lin-9 DREAM MuvB core complex component 2 2
MIRT680743 CA5B carbonic anhydrase 5B 2 2
MIRT682481 LIX1L limb and CNS expressed 1 like 2 4
MIRT682701 PSMD9 proteasome 26S subunit, non-ATPase 9 2 2
MIRT682759 MDM2 MDM2 proto-oncogene 2 2
MIRT682811 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT682847 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT682896 XIAP X-linked inhibitor of apoptosis 2 2
MIRT682916 FAM73A mitoguardin 1 2 2
MIRT682935 ZNF292 zinc finger protein 292 2 2
MIRT682953 RPL12 ribosomal protein L12 2 2
MIRT682972 NF2 neurofibromin 2 2 2
MIRT683033 SUSD5 sushi domain containing 5 2 2
MIRT683081 A1BG alpha-1-B glycoprotein 2 2
MIRT683105 TIMM10B translocase of inner mitochondrial membrane 10B 2 2
MIRT686640 TMEM184C transmembrane protein 184C 2 2
MIRT687444 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT688401 EMC8 ER membrane protein complex subunit 8 2 2
MIRT688886 C3orf70 chromosome 3 open reading frame 70 2 2
MIRT689148 IRAK1BP1 interleukin 1 receptor associated kinase 1 binding protein 1 2 2
MIRT689234 RPS19 ribosomal protein S19 2 2
MIRT689306 C5AR2 complement component 5a receptor 2 2 2
MIRT689364 ZNF101 zinc finger protein 101 2 2
MIRT689498 SCARF1 scavenger receptor class F member 1 2 2
MIRT689655 RBM23 RNA binding motif protein 23 2 2
MIRT689897 SOD2 superoxide dismutase 2 2 2
MIRT690150 PPIL6 peptidylprolyl isomerase like 6 2 2
MIRT690601 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT690805 FAHD1 fumarylacetoacetate hydrolase domain containing 1 2 2
MIRT690946 GLG1 golgi glycoprotein 1 2 2
MIRT691388 ATP13A4 ATPase 13A4 2 2
MIRT691408 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT692175 LRRC3C leucine rich repeat containing 3C 2 2
MIRT692235 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT693283 GINM1 glycoprotein integral membrane 1 2 2
MIRT693439 TPGS1 tubulin polyglutamylase complex subunit 1 2 2
MIRT693460 HIST1H2AG histone cluster 1 H2A family member g 2 2
MIRT693768 ZNF383 zinc finger protein 383 2 2
MIRT694018 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT694236 ZNF749 zinc finger protein 749 2 2
MIRT694321 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT694347 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT694430 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT695763 WDR35 WD repeat domain 35 2 2
MIRT696167 TIPIN TIMELESS interacting protein 2 2
MIRT696417 DOCK7 dedicator of cytokinesis 7 2 2
MIRT696543 C3 complement C3 2 2
MIRT696998 CCDC80 coiled-coil domain containing 80 2 2
MIRT697232 ZYG11A zyg-11 family member A, cell cycle regulator 2 2
MIRT697806 UBXN2A UBX domain protein 2A 2 2
MIRT697944 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT698161 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT698778 STK4 serine/threonine kinase 4 2 2
MIRT700259 RBM12B RNA binding motif protein 12B 2 2
MIRT700970 PDK3 pyruvate dehydrogenase kinase 3 2 2
MIRT701251 NUP35 nucleoporin 35 2 2
MIRT701607 MYPN myopalladin 2 2
MIRT702457 KIAA1467 family with sequence similarity 234 member B 2 2
MIRT702613 ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein like 2 2 2
MIRT702691 IRGQ immunity related GTPase Q 2 2
MIRT702934 HMX3 H6 family homeobox 3 2 2
MIRT702991 HERPUD2 HERPUD family member 2 2 2
MIRT703148 GPR137C G protein-coupled receptor 137C 2 2
MIRT703980 EMC1 ER membrane protein complex subunit 1 2 2
MIRT704569 CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2 2
MIRT705065 C4orf32 family with sequence similarity 241 member A 2 2
MIRT705447 ATL2 atlastin GTPase 2 2 2
MIRT705856 AFF3 AF4/FMR2 family member 3 2 2
MIRT705886 ADIPOR2 adiponectin receptor 2 2 2
MIRT714370 HP1BP3 heterochromatin protein 1 binding protein 3 2 2
MIRT715784 PHF12 PHD finger protein 12 2 2
MIRT715864 KIAA0101 PCNA clamp associated factor 2 2
MIRT715947 NUP93 nucleoporin 93 2 2
MIRT716132 THOC5 THO complex 5 2 2
MIRT717084 EBF4 early B-cell factor 4 2 2
MIRT725424 HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 2 2
MIRT736091 GREM1 gremlin 1, DAN family BMP antagonist 3 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4793 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-miR-4793-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4793-3p Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4793-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)

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