pre-miRNA Information
pre-miRNA hsa-mir-873   
Genomic Coordinates chr9: 28888879 - 28888955
Synonyms MIRN873, hsa-mir-873, MIR873
Description Homo sapiens miR-873 stem-loop
Comment This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-873-3p
Sequence 46| GGAGACUGAUGAGUUCCCGGGA |67
Evidence Not_experimental
Experiments
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs760528397 3 dbSNP
rs773403294 9 dbSNP
rs1273846238 13 dbSNP
rs1339396073 15 dbSNP
rs1247999695 18 dbSNP
rs377380148 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol KNSTRN   
Synonyms C15orf23, HSD11, SKAP, TRAF4AF1
Description kinetochore localized astrin/SPAG5 binding protein
Transcript NM_001142761   
Other Transcripts NM_001142762 , NM_033286   
Expression
Putative miRNA Targets on KNSTRN
3'UTR of KNSTRN
(miRNA target sites are highlighted)
>KNSTRN|NM_001142761|3'UTR
   1 AGGATTTCATCGTTCCAGTTTAGATACAGGAGTCTAGTCCCTCTCTACTACTAGAGGGACAATTCCTAAAACCAGTGCAT
  81 AGAAATAAAATCTAAAATAGAAGATACAGTCTGTTGATACTCCAGTGGTCTTCCTTAGTGGAATAGGAGCATAATGTTCT
 161 GATGTGGGAATTGTGTTTCCTGTTAGTCAAGAGTTTTGTGTATGTGTTGTTTTCTTTTGGAATGTCTTTCCATGCAGGCC
 241 TTAAAGGTAAAGCTGGAGATGAAAGAGGAAAGAGTCCGATTCCTAGAACAGCAAACCTTATGTAACAATCAAGTAAATGA
 321 TTTAACAACAGCCCTTAAGGAAATGGAGCAGCTATTAGAAATGTAAGAAGAAGCAAGTGGCCAGATGGCTCCCTCTTGGG
 401 CATAAAATCTCAGAGGAAGCTACTTAGGACATCATCTTGGCCATGATCTTCTGGGACTCACCATCTCCAGAATGAAAACA
 481 ATTTCTACAGTAGACTTAAGGACAGTTTATGCTGAAATGGCAATTCCTCATTTAAGCAAGTTTTCCCAACCTTCAGGTTG
 561 GTCAGCCCTCCTGAGCCTCACAGGTGGATAATTGAGGCCTACAAGAGAGGGGAGCCTAGGAGCTTGGATTGACCTTCTAG
 641 TCAACCACCTGACTTCAGCACACCATTACAATCGGGAGACTAAACCAACAACCAGAGGATCTAAAATGTCACATTCAGAT
 721 TTTCAGGAAGAAAATCTTCATTACAGTGGAGCACAAATGTTCCATACAAGACATCATTGAGGAGCCATGCTGTCCCCTTC
 801 TAACCTGAAACACATTCTTTCCCATCCTGGTTGGGCTTCTGTACCTCCTTATTAATTTATGAACCTGAAGTTGCTTGAAG
 881 TGTTTTGGGCTTAATAAATGGGGTGAAAGTATAGGTAGCAGTAACACCTACATGAAACAATACACCTTGGATCTTTTAAT
 961 CTAAATTACTTTTCTTTTTTAAGTCTACTTTTAAAATAAATACTTCTGTAAATATTCTGACTGTAACATTGAGGAATGAA
1041 AATAGCCTTTTAACCTAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' agggccCUUGAGUAGUCAGAgg 5'
                |||  :| ||||||  
Target 5' aaaataGAAGATA-CAGTCTgt 3'
94 - 114 127.00 -8.00
2
miRNA  3' agGGCCCUUGAGUAGUCAGAGg 5'
            :| ||:||||| || |||| 
Target 5' ctTCTGGGACTCACCA-TCTCc 3'
448 - 468 124.00 -24.00
3
miRNA  3' agggcCCUUGAGUA-----GUCAGAgg 5'
               ||| :||||     ||||:|  
Target 5' ----aGGATTTCATCGTTCCAGTTTag 3'
1 - 23 121.00 -15.04
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
786753 366 ClinVar
COSN30449409 9 COSMIC
COSN18325575 69 COSMIC
COSN13618052 83 COSMIC
COSN25762928 106 COSMIC
COSN30511453 107 COSMIC
COSN30473649 134 COSMIC
COSN30151120 142 COSMIC
COSN30151051 157 COSMIC
COSN31511494 184 COSMIC
COSN26563589 201 COSMIC
COSN30515896 224 COSMIC
COSN31567331 227 COSMIC
COSM5097163 234 COSMIC
COSM5082548 239 COSMIC
COSM274217 253 COSMIC
COSM9529328 262 COSMIC
COSM4054354 278 COSMIC
COSM9086081 279 COSMIC
COSM9748753 286 COSMIC
COSM4572849 300 COSMIC
COSM256445 317 COSMIC
COSM3987926 364 COSMIC
COSN31510306 416 COSMIC
COSN30163000 456 COSMIC
COSN28878502 459 COSMIC
COSN31601629 544 COSMIC
COSN6272639 988 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs776493263 6 dbSNP
rs748097193 12 dbSNP
rs769517906 13 dbSNP
rs376425558 16 dbSNP
rs766641415 19 dbSNP
rs1221563886 22 dbSNP
rs1477077545 23 dbSNP
rs774708387 25 dbSNP
rs1490403917 26 dbSNP
rs1255927781 27 dbSNP
rs759592377 28 dbSNP
rs1255183512 31 dbSNP
rs1266442830 31 dbSNP
rs1439501853 34 dbSNP
rs767611992 37 dbSNP
rs1266650470 43 dbSNP
rs753180572 45 dbSNP
rs756600383 46 dbSNP
rs1165521182 47 dbSNP
rs563646616 49 dbSNP
rs754141045 51 dbSNP
rs1318056919 57 dbSNP
rs1006120600 59 dbSNP
rs879065223 60 dbSNP
rs1278534385 61 dbSNP
rs1218193064 65 dbSNP
rs8037941 77 dbSNP
rs758266561 88 dbSNP
rs1363942733 92 dbSNP
rs181989004 106 dbSNP
rs1455090605 107 dbSNP
rs1345783679 112 dbSNP
rs994229109 118 dbSNP
rs917683022 126 dbSNP
rs955390235 132 dbSNP
rs1194287493 137 dbSNP
rs1449105410 140 dbSNP
rs1246350760 142 dbSNP
rs1467384596 146 dbSNP
rs970343600 147 dbSNP
rs1171766508 151 dbSNP
rs980454084 160 dbSNP
rs1440600935 162 dbSNP
rs1281866949 166 dbSNP
rs1018646586 171 dbSNP
rs56317498 182 dbSNP
rs1292990647 186 dbSNP
rs775993148 187 dbSNP
rs758054217 189 dbSNP
rs1362361000 198 dbSNP
rs1399002944 199 dbSNP
rs779750968 201 dbSNP
rs1328849903 203 dbSNP
rs1412882647 203 dbSNP
rs913768148 204 dbSNP
rs1171489993 205 dbSNP
rs751216309 207 dbSNP
rs200872015 210 dbSNP
rs748068908 213 dbSNP
rs1359744330 218 dbSNP
rs769806376 221 dbSNP
rs1289324769 222 dbSNP
rs1444336176 223 dbSNP
rs1429186788 225 dbSNP
rs777713107 230 dbSNP
rs201042301 233 dbSNP
rs201289104 235 dbSNP
rs774761615 236 dbSNP
rs1185531562 237 dbSNP
rs1243764094 239 dbSNP
rs565554379 240 dbSNP
rs1161975612 259 dbSNP
rs201814444 263 dbSNP
rs1462862636 264 dbSNP
rs1180428241 270 dbSNP
rs1255937036 270 dbSNP
rs775588585 275 dbSNP
rs761096365 277 dbSNP
rs369930942 278 dbSNP
rs200025938 279 dbSNP
rs186157950 283 dbSNP
rs765884043 286 dbSNP
rs1249306919 289 dbSNP
rs1310207988 290 dbSNP
rs749911100 293 dbSNP
rs927580566 293 dbSNP
rs748267102 296 dbSNP
rs1307669959 299 dbSNP
rs1327807283 300 dbSNP
rs375197641 302 dbSNP
rs770205245 303 dbSNP
rs751211021 308 dbSNP
rs1337393292 309 dbSNP
rs1205413472 318 dbSNP
rs1231156437 320 dbSNP
rs754619508 323 dbSNP
rs1460975827 324 dbSNP
rs752195768 329 dbSNP
rs755678785 331 dbSNP
rs777913445 332 dbSNP
rs749214550 334 dbSNP
rs1038308234 335 dbSNP
rs1217575509 338 dbSNP
rs1371644864 341 dbSNP
rs770890334 343 dbSNP
rs897172783 344 dbSNP
rs778725206 352 dbSNP
rs746096458 353 dbSNP
rs569657077 355 dbSNP
rs1363676460 357 dbSNP
rs139286584 366 dbSNP
rs369469587 372 dbSNP
rs768711798 374 dbSNP
rs1225104902 375 dbSNP
rs777174472 378 dbSNP
rs1163225303 379 dbSNP
rs189861256 381 dbSNP
rs1051616770 390 dbSNP
rs200552828 392 dbSNP
rs1262523057 394 dbSNP
rs1486326327 396 dbSNP
rs1204702302 400 dbSNP
rs376622940 401 dbSNP
rs369417225 404 dbSNP
rs1200570619 408 dbSNP
rs1429249173 411 dbSNP
rs1196973508 412 dbSNP
rs373391184 416 dbSNP
rs11541643 419 dbSNP
rs1336651191 430 dbSNP
rs1424595945 432 dbSNP
rs1293876886 442 dbSNP
rs115872791 446 dbSNP
rs766983922 447 dbSNP
rs1333856165 463 dbSNP
rs142745139 468 dbSNP
rs1391966517 470 dbSNP
rs61298638 482 dbSNP
rs1270459091 505 dbSNP
rs12595509 509 dbSNP
rs536862947 515 dbSNP
rs970480931 521 dbSNP
rs991921109 522 dbSNP
rs1469066544 530 dbSNP
rs1025180379 546 dbSNP
rs980413186 548 dbSNP
rs1212659934 551 dbSNP
rs531911239 555 dbSNP
rs1419145048 556 dbSNP
rs1033387747 562 dbSNP
rs971577281 569 dbSNP
rs1191329521 576 dbSNP
rs1291768392 577 dbSNP
rs1273601485 579 dbSNP
rs1207813774 580 dbSNP
rs764242371 581 dbSNP
rs775192611 588 dbSNP
rs1262413944 596 dbSNP
rs1322195348 608 dbSNP
rs980703867 618 dbSNP
rs557070430 621 dbSNP
rs1330571245 623 dbSNP
rs150753348 630 dbSNP
rs1443411249 638 dbSNP
rs1371929830 640 dbSNP
rs941585374 646 dbSNP
rs913810370 654 dbSNP
rs11541641 656 dbSNP
rs1453906957 657 dbSNP
rs976567482 658 dbSNP
rs1171142760 662 dbSNP
rs918546499 663 dbSNP
rs922675422 671 dbSNP
rs932763204 674 dbSNP
rs1051179169 675 dbSNP
rs1263828659 677 dbSNP
rs1049715039 702 dbSNP
rs1205612908 706 dbSNP
rs137878630 711 dbSNP
rs1241810341 712 dbSNP
rs1236503855 720 dbSNP
rs941367526 721 dbSNP
rs1037248831 728 dbSNP
rs942530558 735 dbSNP
rs573300179 740 dbSNP
rs897420061 747 dbSNP
rs1395984722 749 dbSNP
rs1374112244 756 dbSNP
rs1171202112 758 dbSNP
rs903696566 761 dbSNP
rs78181034 762 dbSNP
rs1395362320 763 dbSNP
rs571726708 775 dbSNP
rs1014404823 778 dbSNP
rs1024508810 780 dbSNP
rs906277033 786 dbSNP
rs545390461 790 dbSNP
rs1193563798 791 dbSNP
rs565588986 791 dbSNP
rs753552809 798 dbSNP
rs1000746002 801 dbSNP
rs1033852784 806 dbSNP
rs1421053247 815 dbSNP
rs531185176 835 dbSNP
rs892124684 848 dbSNP
rs1213065084 853 dbSNP
rs989569368 855 dbSNP
rs1344169158 860 dbSNP
rs544578212 862 dbSNP
rs1428232393 868 dbSNP
rs966626726 882 dbSNP
rs1375488059 889 dbSNP
rs1327553388 896 dbSNP
rs139964319 897 dbSNP
rs1407881761 897 dbSNP
rs561572320 903 dbSNP
rs530219538 904 dbSNP
rs976536150 906 dbSNP
rs922479466 916 dbSNP
rs1168353605 924 dbSNP
rs954120725 928 dbSNP
rs985529697 936 dbSNP
rs765021335 939 dbSNP
rs1312901463 941 dbSNP
rs1355939694 942 dbSNP
rs941348502 943 dbSNP
rs980557897 951 dbSNP
rs1034443860 956 dbSNP
rs962851959 957 dbSNP
rs1273967457 962 dbSNP
rs974291795 965 dbSNP
rs918872603 966 dbSNP
rs929979632 966 dbSNP
rs1234474014 978 dbSNP
rs1445442918 984 dbSNP
rs1212548316 985 dbSNP
rs987228866 992 dbSNP
rs1278451167 1000 dbSNP
rs1238380169 1002 dbSNP
rs1037455767 1007 dbSNP
rs1329094302 1016 dbSNP
rs1461182545 1022 dbSNP
rs1460767759 1025 dbSNP
rs1392066256 1028 dbSNP
rs912582307 1029 dbSNP
rs1182270786 1030 dbSNP
rs1407071698 1041 dbSNP
rs1175621099 1046 dbSNP
rs1382774458 1047 dbSNP
rs918834634 1051 dbSNP
rs950317160 1056 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' agggcccuugaguagUCAGAGg 5'
                         |||||| 
Target 5' ---------------AGUCUCa 3'
1 - 7
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions Prostate Tissue
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRX1760630. RNA binding protein: AGO2. Condition:AGO-CLIP-22RV1_A ...

- Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al., 2016, Neoplasia (New York, N.Y.).

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' agggcccuugaguagUCAGAGg 5'
                         |||||| 
Target 5' ---------------AGUCUCa 3'
1 - 7
Article - Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al.
- Neoplasia (New York, N.Y.), 2016
MicroRNA (miRNA) deregulation in prostate cancer (PCa) contributes to PCa initiation and metastatic progression. To comprehensively define the cancer-associated changes in miRNA targeting and function in commonly studied models of PCa, we performed photoactivatable ribonucleoside-enhanced cross-linking immunoprecipitation of the Argonaute protein in a panel of PCa cell lines modeling different stages of PCa progression. Using this comprehensive catalogue of miRNA targets, we analyzed miRNA targeting on known drivers of PCa and examined tissue-specific and stage-specific pathway targeting by miRNAs. We found that androgen receptor is the most frequently targeted PCa oncogene and that miR-148a targets the largest number of known PCa drivers. Globally, tissue-specific and stage-specific changes in miRNA targeting are driven by homeostatic response to active oncogenic pathways. Our findings indicate that, even in advanced PCa, the miRNA pool adapts to regulate continuing alterations in the cancer genome to balance oncogenic molecular changes. These findings are important because they are the first to globally characterize miRNA changes in PCa and demonstrate how the miRNA target spectrum responds to staged tumorigenesis.
LinkOut: [PMID: 27292025]
CLIP-seq Support 1 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000608100.1 | 3UTR | AGUCUCACUCUGUUGCCUAGGCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
108 hsa-miR-873-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081178 MIDN midnolin 2 4
MIRT109809 ZFX zinc finger protein, X-linked 2 4
MIRT242383 TMC5 transmembrane channel like 5 2 4
MIRT444003 METRN meteorin, glial cell differentiation regulator 2 4
MIRT444097 SEPHS1 selenophosphate synthetase 1 2 2
MIRT446158 RPL12 ribosomal protein L12 2 2
MIRT446859 SAMD9L sterile alpha motif domain containing 9 like 2 2
MIRT447275 FZD5 frizzled class receptor 5 2 2
MIRT447391 TMPRSS15 transmembrane protease, serine 15 2 2
MIRT448817 FKBP1A FK506 binding protein 1A 2 4
MIRT450582 HIST1H2BG histone cluster 1 H2B family member g 2 2
MIRT451776 USP36 ubiquitin specific peptidase 36 2 2
MIRT457961 ABCC5 ATP binding cassette subfamily C member 5 2 4
MIRT458424 KLHL38 kelch like family member 38 2 4
MIRT461383 SLFN12L schlafen family member 12 like 2 2
MIRT467793 SLC2A14 solute carrier family 2 member 14 2 2
MIRT476517 GABRB1 gamma-aminobutyric acid type A receptor beta1 subunit 2 2
MIRT480290 C7orf73 short transmembrane mitochondrial protein 1 2 4
MIRT482745 HES7 hes family bHLH transcription factor 7 2 10
MIRT483189 HIST1H2AH histone cluster 1 H2A family member h 2 6
MIRT486545 DCTN4 dynactin subunit 4 2 2
MIRT486581 ZNF619 zinc finger protein 619 2 2
MIRT492604 POLR3E RNA polymerase III subunit E 2 2
MIRT494130 DCAF7 DDB1 and CUL4 associated factor 7 2 6
MIRT496023 ZBED3 zinc finger BED-type containing 3 2 2
MIRT497121 NBEAL1 neurobeachin like 1 2 2
MIRT497400 TMEM245 transmembrane protein 245 2 2
MIRT501410 RANBP10 RAN binding protein 10 2 2
MIRT510947 PPTC7 PTC7 protein phosphatase homolog 2 6
MIRT512494 ARID2 AT-rich interaction domain 2 2 2
MIRT512595 ZNF783 zinc finger family member 783 2 2
MIRT512612 CNTN4 contactin 4 2 2
MIRT517808 UGDH UDP-glucose 6-dehydrogenase 2 6
MIRT520686 TMED7 transmembrane p24 trafficking protein 7 2 4
MIRT526179 HEPH hephaestin 2 2
MIRT532568 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT533979 TADA2A transcriptional adaptor 2A 2 2
MIRT538622 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT539703 EIF3H eukaryotic translation initiation factor 3 subunit H 2 2
MIRT539806 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT540422 FAM83F family with sequence similarity 83 member F 2 2
MIRT540506 CXCL10 C-X-C motif chemokine ligand 10 2 2
MIRT540619 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT542423 ZNF331 zinc finger protein 331 2 2
MIRT542454 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT543383 CC2D2A coiled-coil and C2 domain containing 2A 2 2
MIRT544777 CSTF2T cleavage stimulation factor subunit 2 tau variant 2 4
MIRT544923 ERCC4 ERCC excision repair 4, endonuclease catalytic subunit 2 2
MIRT549768 ZNF611 zinc finger protein 611 2 4
MIRT551242 COLEC10 collectin subfamily member 10 2 2
MIRT560474 ENSA endosulfine alpha 2 2
MIRT569738 GPR173 G protein-coupled receptor 173 2 2
MIRT571297 CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 2 2
MIRT572345 CKAP2L cytoskeleton associated protein 2 like 2 2
MIRT573112 ERBB2IP erbb2 interacting protein 2 2
MIRT607744 ANGPT4 angiopoietin 4 2 2
MIRT607903 SPRYD4 SPRY domain containing 4 2 2
MIRT611744 SERPING1 serpin family G member 1 2 4
MIRT615101 BNC2 basonuclin 2 2 2
MIRT619124 CD40LG CD40 ligand 2 2
MIRT625572 ANKRD42 ankyrin repeat domain 42 2 2
MIRT629038 KLLN killin, p53-regulated DNA replication inhibitor 2 2
MIRT633986 SLC35E2 solute carrier family 35 member E2 2 2
MIRT635675 COX18 COX18, cytochrome c oxidase assembly factor 2 4
MIRT637471 DEFB105B defensin beta 105B 2 4
MIRT637503 DEFB105A defensin beta 105A 2 4
MIRT639735 MAP2K2 mitogen-activated protein kinase kinase 2 2 2
MIRT640730 C9orf64 chromosome 9 open reading frame 64 2 2
MIRT645364 C9orf47 chromosome 9 open reading frame 47 2 2
MIRT647938 RNF152 ring finger protein 152 2 2
MIRT649400 SH2D4A SH2 domain containing 4A 2 2
MIRT656860 KIN Kin17 DNA and RNA binding protein 2 2
MIRT663470 POFUT2 protein O-fucosyltransferase 2 2 2
MIRT663507 NKAPL NFKB activating protein like 2 4
MIRT667690 KNSTRN kinetochore localized astrin/SPAG5 binding protein 2 2
MIRT677403 PCNP PEST proteolytic signal containing nuclear protein 2 2
MIRT678682 SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 2 2
MIRT678789 NUPL2 nucleoporin like 2 2 2
MIRT680649 KIAA1456 KIAA1456 2 2
MIRT682450 MTX3 metaxin 3 2 2
MIRT682740 CA6 carbonic anhydrase 6 2 2
MIRT684421 TUFT1 tuftelin 1 2 2
MIRT690535 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT690595 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT690771 PLA2G2C phospholipase A2 group IIC 2 2
MIRT692233 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT693667 MXRA7 matrix remodeling associated 7 2 2
MIRT695551 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT695870 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT696214 LYZ lysozyme 2 2
MIRT698368 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT700795 PHTF2 putative homeodomain transcription factor 2 2 2
MIRT701640 MYLK3 myosin light chain kinase 3 2 2
MIRT702989 HERPUD2 HERPUD family member 2 2 2
MIRT703627 FBXL3 F-box and leucine rich repeat protein 3 2 2
MIRT703783 FAM102B family with sequence similarity 102 member B 2 2
MIRT704293 DDX19B DEAD-box helicase 19B 2 2
MIRT704828 CDC73 cell division cycle 73 2 2
MIRT705014 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT708480 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT710770 PHF7 PHD finger protein 7 2 2
MIRT718918 TRIM66 tripartite motif containing 66 2 2
MIRT720390 ZNF549 zinc finger protein 549 2 2
MIRT720593 TTC39C tetratricopeptide repeat domain 39C 2 2
MIRT723515 SIGLEC8 sialic acid binding Ig like lectin 8 2 2
MIRT724458 PRKX protein kinase, X-linked 2 2
MIRT737267 UMAD1 UBAP1-MVB12-associated (UMA) domain containing 1 3 0
MIRT737356 ZIC2 Zic family member 2 4 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-873 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-873 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-873 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-873 Cisplatin 5460033 NSC119875 approved resistant cell line (OE19)
hsa-mir-873 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-mir-873 Decitabine 451668 approved sensitive tissue (esopheageal cancer)
hsa-miR-873-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-873-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-873-3p Cisplatin 5460033 NSC119875 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-873-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-873-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-873-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-873-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)
hsa-miR-873-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-873-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-873-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-873-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-873-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-873-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

Error report submission