miRTarBase - #MIRT676074


—
pre-miRNA Information
pre-miRNA hsa-mir-4680   
Genomic Coordinates chr10: 110898090 - 110898155
Description Homo sapiens miR-4680 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4680-5p
Sequence 5| AGAACUCUUGCAGUCUUAGAUGU |27
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1274530692 2 dbSNP
rs780271274 5 dbSNP
rs1461423681 7 dbSNP
rs749729920 8 dbSNP
rs1252920446 10 dbSNP
rs201739274 11 dbSNP
rs774971106 19 dbSNP
rs748132091 22 dbSNP
rs773643180 22 dbSNP
rs1235425484 23 dbSNP
Putative Targets

Gene Information
Gene Symbol TIMM50   
Synonyms TIM50, TIM50L
Description translocase of inner mitochondrial membrane 50
Transcript NM_001001563   
Expression
Putative miRNA Targets on TIMM50
3'UTR of TIMM50
(miRNA target sites are highlighted)		 
>TIMM50|NM_001001563|3'UTR
   1 ACTCTGGGCCTCCTCAAACTCAGTGCCTGGGTCCAGGGCCCCAGTGCTTCCAGACCAAGACTTGGGCCACCACTTGTCCA
  81 ATAAAGTACATCCCAGACGCCACACCTGCTGTGTCCCGAGAGTCTCCAGATGGGGGCATCAGGGTGAGGTCCGGGACTCT
 161 TGGGTCATCGTCCCACAGTGGCTGATCGGCTGCCAAGCACAGTGGGGGTGCTTTGTTGGATCAGAGCAGATTTTTCACCC
 241 TGGTCTCGGAATCTAAAAACCCTCGCTGTGTCTTCCTGTGTGTTGCGTGATCTGTGAAAAATACATCTCCCTCTGACCAC
 321 AGACTCCTCATCTGTGGAGAAGGGAAGAGAGGATGGCACTTGGCTTTAAAGACAGGTAGCTGCCAGGCTACTGTGGAGAG
 401 AATGTGTTATGGGCCTAGTGGGCCTCTGGTGGACCAGAGATTACCCCTCTCAACAGGCCAGCTGCTGGTTGGCTCCAGCC
 481 AGTGTGGCCCTGGGGTAAAGGGGGCCTGGAGTTGCTTGACACGCCAGTTGTTCAAAAGAAGCAAGAACTTGGGAATATTT
 561 TTTTTTTTTTTTTGAGACAGGGTCTCACTGTTGCCCAGGCTGGAGTGCATTGATGTGATCTTAGCTTACAACAGCCTTGA
 641 CCTCCCGGCTCAAGTGATCTCCAAGTGACCCTCCTGCCTCAGCCTCCTGAGTACCCTCCTGGGGACTACAGGTGCGTGCT
 721 ACCATACCCAGCTAATTTAAACAAATTTTTTTTTTGTAGAGATGGGGTCTTGGTGCCCAAGCTGGTCTCAAACTCCTAGT
 801 CTTAAGCAATCTTCCTGCTTTGGCCTCCCAAAGCGCTAGGATTCCAGGTGTGAGCTACTGTGCCCAGCTAAAATAGGGAT
 881 TTTTATATTAAATCTCCCTATTTTAAAATGTTGGCTCCTAGCGGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTG
 961 GGAGGCTGAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTCAACATGGAGAAACCCCATCTCTACTAAAA
1041 ATACAAAATTAGCTGGGCGTGGTGGAGCATGCCTGTGATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAAC
1121 CTGGGAGGCGGAGGTTGTGGTGAGCCGAGATCGCACCATTGCACTCCAGCCTGGGCAACAGCAGCGAAACTCCATCTCAA
1201 AAAATAAAATAAAATAAAAATAAAATGTTGGCTTCTAACTAAAACAGGCAGATATGTAGCAGTGTTCTCCACTGGAACTT
1281 TCTGTGATGTTTGGTTCATGTTCTAGGTCTGTACTGTCCAGTACAGTAGCCAGTGGCCACATAAACCTTTGTTTTTTTTT
1361 TTTGAGACGGAGTTTCGCTCTTATTGCCCAGGCTGGAGTGCAATGGCACGACGTCGGCTCACCACATCCTCCGCCTCCCG
1441 GGTTCAAGCAATGCTCCCGCCTCAACCTCCCAAGTAGCTGAGATTACAGGCGCACACCACCACGCCCGGCTAATTTTTGT
1521 ATTTTTTTAGTAGAGACAGGGTTTCACCATGTTGGTTAGGCTGGTCTCGAACTCCTGACCTCGTGATCCGCCCGCCTCGG
1601 CCTCCCAAAGTGCTGGGATTGCAGGCATGAGCCACCATGCCTGGCCCCACATAAAGTTTCTGAGCACTTGAAATGTGGCT
1681 AGTGTGACTGAGAAACTGAATTTTTAATTTTGTTTGAGACTGGGCACAGTGGCTCACGCCTGTAATCCTGACACTTTGGG
1761 AGGCCGAAGCAGGAGGATTGCTTGAATCCAGGAGTACGAGACCACCCTGGGCAACATGGTGAAATCCTGCCTCTAAAAAA
1841 AAAACAAAGTAACGAGCCCAGCGAGGTTATGCATACCTGTAGTCCCAGCTACGTGAGAGGCTGAGGTGGGAGGAATCCCT
1921 TGAGCCAAGGAGGTCGTGCGTGGCTGTGATGATCTGTGATCGTGCCGCTAAATTCTAGCCTGGGCAACAGAGCGAGACCC
2001 TGTCTCAAAAAAAAAAAAAAAAAAAAAAAAACCTTAAGATTTTTTTTTGGAGTCAGGGTCTCGCTGTGTCGCCCAGGCTG
2081 GAGCACAGTGGTGTAACTATAGCTCACTGCAGTGTTGAACTTCTGGGCTCAAACAATCTTCCTGCCTTGGCCTCCCCAAA
2161 TGCTGAGATTATAGGAGTGAGCCACTCTGCCCAACTACTTTTAATTAAATAGCCACATGTGTCTCCTGTATTGACAGTAC
2241 CACTGTGTATTAAGAGTATGAGTCCCAGATTGTGTAAGTTCAAATCCAAGCTCTACCACTTCTCGGCTGGCTTGTGATCC
2321 TGTGCAAGTTACTTTACCTCTCAGTGCCTCGGTTTCTACATTTATAAAATAATAACTGGGCAGGCACAGTGGCTCATGGC
2401 TGTCATCCCAACACTTCAGGAGGCCGAGGTGGGAGGATCGCCTGAGGCCAGGAGTTGGAGAGCAGCCTGGGCAACATGGG
2481 AAGAGCCTGTCTCTTGCGGGGGGGGGAGAAGAAAGTTCTTGTCTCAGGCTAGCTTTGGGGACCAAATGAAGCACTCCCAT
2561 GTAGGCACTCAAATGGAACTATGTAAACCTTAGGCAAGGCACCTCTGCCTCAGTTTCCTCATCTCTAAAATGGGGTGATG
2641 GTAGTATGTTAGCAGAGTGGTTGTGAGGAGTGAACGGGACAGTCCGTATGTGGGTTATATGTATATATTCCCAGGTGCTT
2721 GCTGTTACCAGGCCATATGGGTTATTCACAGATTGAAATATCTTAGCTGGGCACGGTGGCTCACCCCTATAATCCCAGCA
2801 CTTTGGGAGACCGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTC
2881 TACTAAAAAAATACAAATAAATTAGCTGGGCATGGTGGTGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGA
2961 GAATCGATTAAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCACACCATTGCACTCCAGCCTGGGCGACAGAGTAAG
3041 GCTCTGTCTCCAAAAAAAAAAAAAAAAAAAAACAAAAAAAAAACCAGTTTGACTTTATCTCCCTCGCCCTGCCTCCATCC
3121 CCACATTGCCCCCCACTATCCCAGTCTCTCCTACTCCAGCCTTCATCTAGTGCTAACTGATTAAATATTCTAAGATGACC
3201 TTCTCTGGTGTGTGTGATGATAATTAAAAGGCATTCAGAACTGTGTGGACCAGACTGAACCTCTGCACTCTAGATTTTTT
3281 TTTTTTTGAAGCCTCTACAAAGGATAATTAAAATTTACACCATGACTCTTTGTCCTGGGGTGCACTGTCTGTAAGCCGGT
3361 GGAGTTATTTCCCAAAATCCTTGGTCCTTCCCAGCTTGAGGAAGTCTGCAGGACTGAGGGAGGGGACCTGTGCTTTTTTT
3441 TTTGTTTTTTTGAGATGGAGTCTCTGTTGCCCAGGCTGGAGTGCAGTGGGGCGATCTCGGCTCACTGCACCCTGCACCTC
3521 CTGGGTTCAAGTGATTCTCCTGCCTCAGGCTCCCAAGTAGCTGGGATTACAGGCGTGTGCCACTGTCAGGCCTCTGAGCC
3601 CAAGCCAAGCCATCGCATCCCCTGTGCCTTGCACATATACACCCAGATGGCCTGAAGTAACTGAAGAATCACAAAAGAAG
3681 TGAAAAGGCCCTGCCCCGCCTTAACTGATGACATTCCACCATTGTGATTTGTTCCTGCCCCACCTTAACTGAGTGATTAA
3761 CCCTGCAAATTTCCTTCTCCTGGCTCAGAAGCACCCCCACTGAGCACCTTGCGACCCCCCACTCCTGCCCGCCCTTTGAC
3841 TGTAATTTTCCATTACCTTCCCAAATACTATAAAACAGCCCCACCCCTATCTCCCTTCGCTGACTCTTTTCGGACTCAGC
3921 CCACCTGCACCCAGGTGAAATAAACAGCTTTATTGCTCACACAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugUAGAUUCUGACGUUCUCAAGa 5'
            | ||:||::  ||:|||||| 
Target 5' tcACCTGAGGT--CAGGAGTTCa 3'
 980 - 1000 149.00 -17.10
2 
miRNA  3' ugUAGAUUCUGACGUUCUCAAGa 5'
            | ||:||::  ||:|||||| 
Target 5' tcACCTGAGGT--CAGGAGTTCg 3'
 2825 - 2845 149.00 -17.30
3 
miRNA  3' uguaGAUUCUGACGUUCUCAAga 5'
              ||:||:|  ||:|||||  
Target 5' tcgcCTGAGGC--CAGGAGTTgg 3'
 2438 - 2458 131.00 -16.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20079528 10 COSMIC
COSN30454617 22 COSMIC
COSN30455330 36 COSMIC
COSN30541443 47 COSMIC
COSN30166094 121 COSMIC
COSN30140921 144 COSMIC
COSN31603573 147 COSMIC
COSN28881165 153 COSMIC
COSN31591595 193 COSMIC
COSN28879849 204 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs772487623 5 dbSNP
rs1491150039 6 dbSNP
rs762458645 7 dbSNP
rs11428 12 dbSNP
rs1299995804 14 dbSNP
rs1349080517 15 dbSNP
rs368314509 17 dbSNP
rs1295151695 18 dbSNP
rs769411433 22 dbSNP
rs779430915 23 dbSNP
rs1297728567 26 dbSNP
rs748770732 28 dbSNP
rs1243289624 30 dbSNP
rs1311637248 34 dbSNP
rs772586782 42 dbSNP
rs1164858418 51 dbSNP
rs773667090 52 dbSNP
rs867860454 56 dbSNP
rs576373550 59 dbSNP
rs778255611 69 dbSNP
rs1307966408 73 dbSNP
rs963397787 84 dbSNP
rs1250733729 87 dbSNP
rs1366670633 92 dbSNP
rs763722544 93 dbSNP
rs543496720 99 dbSNP
rs568333999 100 dbSNP
rs1264345796 106 dbSNP
rs1330857554 107 dbSNP
rs1223208539 108 dbSNP
rs1361473965 112 dbSNP
rs1239104843 118 dbSNP
rs576957723 118 dbSNP
rs150062064 119 dbSNP
rs559492314 122 dbSNP
rs1309343924 127 dbSNP
rs530233693 131 dbSNP
rs548463987 136 dbSNP
rs140909439 141 dbSNP
rs1303817983 145 dbSNP
rs76609107 153 dbSNP
rs949656971 160 dbSNP
rs1361573755 161 dbSNP
rs1045758120 163 dbSNP
rs927190048 164 dbSNP
rs1160919621 165 dbSNP
rs1207983893 167 dbSNP
rs905176420 170 dbSNP
rs1266456262 171 dbSNP
rs551921740 175 dbSNP
rs1199465697 182 dbSNP
rs75313376 188 dbSNP
rs534681085 189 dbSNP
rs892550862 194 dbSNP
rs1262260238 202 dbSNP
rs1009644057 205 dbSNP
rs1231405425 206 dbSNP
rs1245750153 208 dbSNP
rs1311798705 216 dbSNP
rs1448364137 220 dbSNP
rs1163736850 230 dbSNP
rs1386558138 238 dbSNP
rs1339113420 248 dbSNP
rs1298055002 249 dbSNP
rs1427156593 260 dbSNP
rs1161957381 263 dbSNP
rs1301438758 265 dbSNP
rs1464265850 266 dbSNP
rs1176543694 269 dbSNP
rs1481097502 280 dbSNP
rs546724028 287 dbSNP
rs890314788 288 dbSNP
rs1447495138 302 dbSNP
rs1007457378 305 dbSNP
rs1383085065 310 dbSNP
rs1198475077 312 dbSNP
rs768431136 314 dbSNP
rs537500451 318 dbSNP
rs1047714607 321 dbSNP
rs891305015 323 dbSNP
rs1363215322 326 dbSNP
rs1316213132 327 dbSNP
rs746935296 328 dbSNP
rs190051576 341 dbSNP
rs1017957857 347 dbSNP
rs767840165 353 dbSNP
rs973486404 355 dbSNP
rs1315904173 357 dbSNP
rs770699317 364 dbSNP
rs1395754216 369 dbSNP
rs1404915123 375 dbSNP
rs1336901181 376 dbSNP
rs1242575417 384 dbSNP
rs1470746027 387 dbSNP
rs950447357 397 dbSNP
rs1397565329 404 dbSNP
rs1264756261 407 dbSNP
rs992614270 411 dbSNP
rs781121244 413 dbSNP
rs949608881 419 dbSNP
rs981016063 421 dbSNP
rs772214478 427 dbSNP
rs926874358 431 dbSNP
rs936644375 436 dbSNP
rs535684527 446 dbSNP
rs1185160646 447 dbSNP
rs1443713200 456 dbSNP
rs892500273 458 dbSNP
rs879878964 463 dbSNP
rs945449882 465 dbSNP
rs1039967587 469 dbSNP
rs1196413421 473 dbSNP
rs1183793762 474 dbSNP
rs1264138814 483 dbSNP
rs1244521059 489 dbSNP
rs1051819968 490 dbSNP
rs1384070738 491 dbSNP
rs890271377 502 dbSNP
rs1454287577 503 dbSNP
rs1374153264 505 dbSNP
rs1327630366 506 dbSNP
rs1007819069 507 dbSNP
rs1017488573 523 dbSNP
rs1385685539 524 dbSNP
rs1185167431 525 dbSNP
rs1438099177 527 dbSNP
rs1368328793 537 dbSNP
rs899080734 542 dbSNP
rs1232463626 545 dbSNP
rs1182632439 555 dbSNP
rs1454640251 557 dbSNP
rs557215371 557 dbSNP
rs1222467877 558 dbSNP
rs1360759536 558 dbSNP
rs56770869 558 dbSNP
rs769055171 558 dbSNP
rs575475069 560 dbSNP
rs1348116443 574 dbSNP
rs1032675112 575 dbSNP
rs537437016 576 dbSNP
rs1009995341 577 dbSNP
rs558644112 579 dbSNP
rs1366070107 582 dbSNP
rs971274283 583 dbSNP
rs1417567434 591 dbSNP
rs994795591 604 dbSNP
rs941536245 605 dbSNP
rs972901312 607 dbSNP
rs1407529400 610 dbSNP
rs981653750 611 dbSNP
rs1471271601 614 dbSNP
rs927243747 621 dbSNP
rs1311942051 626 dbSNP
rs536714918 629 dbSNP
rs1241097629 630 dbSNP
rs958598716 631 dbSNP
rs1214913899 633 dbSNP
rs201527863 636 dbSNP
rs1328203528 638 dbSNP
rs201395290 641 dbSNP
rs1285380286 645 dbSNP
rs144854576 646 dbSNP
rs146433366 647 dbSNP
rs1013995907 648 dbSNP
rs575827874 649 dbSNP
rs1047159306 650 dbSNP
rs1304804797 654 dbSNP
rs1024081520 675 dbSNP
rs1420273761 700 dbSNP
rs944246904 703 dbSNP
rs1318694743 705 dbSNP
rs1245816246 706 dbSNP
rs1039875632 712 dbSNP
rs1402695813 715 dbSNP
rs970883980 716 dbSNP
rs181896951 717 dbSNP
rs1001108896 725 dbSNP
rs745529378 728 dbSNP
rs1192198557 729 dbSNP
rs1472439792 742 dbSNP
rs1475362485 745 dbSNP
rs1448392133 746 dbSNP
rs892805745 746 dbSNP
rs958522572 746 dbSNP
rs1010294874 747 dbSNP
rs989718697 751 dbSNP
rs79764197 756 dbSNP
rs1323703103 765 dbSNP
rs1212783485 768 dbSNP
rs185666271 769 dbSNP
rs542087589 774 dbSNP
rs1432572167 775 dbSNP
rs1404189900 785 dbSNP
rs971541670 790 dbSNP
rs1470418919 792 dbSNP
rs563993714 795 dbSNP
rs1168582721 805 dbSNP
rs1051769668 810 dbSNP
rs147898412 815 dbSNP
rs1188672556 816 dbSNP
rs1471973934 822 dbSNP
rs958651124 835 dbSNP
rs112040460 836 dbSNP
rs562415814 839 dbSNP
rs116223183 845 dbSNP
rs899033690 846 dbSNP
rs528105543 847 dbSNP
rs1173691714 854 dbSNP
rs537022373 858 dbSNP
rs1306863984 864 dbSNP
rs1273550825 865 dbSNP
rs1216251882 873 dbSNP
rs141671788 880 dbSNP
rs555572221 889 dbSNP
rs1453708427 895 dbSNP
rs1047703330 901 dbSNP
rs886084760 905 dbSNP
rs1461494257 911 dbSNP
rs1355630047 914 dbSNP
rs1173242254 915 dbSNP
rs1404078213 919 dbSNP
rs1232066549 920 dbSNP
rs564206303 923 dbSNP
rs1481315203 924 dbSNP
rs1444890301 927 dbSNP
rs1024016110 928 dbSNP
rs568204976 929 dbSNP
rs944116839 932 dbSNP
rs1232942461 933 dbSNP
rs1482942514 936 dbSNP
rs1001324427 940 dbSNP
rs1357153913 941 dbSNP
rs1290798431 945 dbSNP
rs11083524 946 dbSNP
rs750749519 948 dbSNP
rs921438803 952 dbSNP
rs1305054568 954 dbSNP
rs11083525 956 dbSNP
rs1374213906 957 dbSNP
rs1403678140 962 dbSNP
rs1034250047 963 dbSNP
rs529075269 968 dbSNP
rs1175605779 972 dbSNP
rs1426877046 973 dbSNP
rs1362423377 990 dbSNP
rs1156564444 998 dbSNP
rs958222163 1001 dbSNP
rs1418129052 1005 dbSNP
rs1408130477 1008 dbSNP
rs190381289 1014 dbSNP
rs1268020888 1017 dbSNP
rs914167904 1026 dbSNP
rs1431666273 1027 dbSNP
rs966649304 1032 dbSNP
rs1054058591 1035 dbSNP
rs987435980 1036 dbSNP
rs1369808672 1043 dbSNP
rs911937858 1046 dbSNP
rs569048089 1059 dbSNP
rs1039149287 1060 dbSNP
rs892683024 1062 dbSNP
rs920406314 1063 dbSNP
rs930483987 1065 dbSNP
rs945761815 1071 dbSNP
rs1345440719 1073 dbSNP
rs1047651620 1074 dbSNP
rs1385921196 1078 dbSNP
rs1304351313 1084 dbSNP
rs886356345 1108 dbSNP
rs766839568 1114 dbSNP
rs1225475377 1121 dbSNP
rs1345363915 1128 dbSNP
rs535230148 1130 dbSNP
rs553564558 1131 dbSNP
rs905554388 1132 dbSNP
rs1200130774 1133 dbSNP
rs879727366 1134 dbSNP
rs1248872732 1139 dbSNP
rs1259446889 1143 dbSNP
rs11665897 1147 dbSNP
rs894318485 1147 dbSNP
rs1032779507 1148 dbSNP
rs1262613712 1151 dbSNP
rs1451421529 1153 dbSNP
rs893947924 1154 dbSNP
rs774756917 1157 dbSNP
rs1389622743 1159 dbSNP
rs1021124091 1160 dbSNP
rs1295341592 1161 dbSNP
rs1383069151 1163 dbSNP
rs10402464 1179 dbSNP
rs570472105 1180 dbSNP
rs1347924633 1181 dbSNP
rs113752397 1182 dbSNP
rs1289089113 1186 dbSNP
rs180775352 1187 dbSNP
rs1176481449 1193 dbSNP
rs1432440750 1196 dbSNP
rs964767105 1199 dbSNP
rs771507625 1201 dbSNP
rs965371904 1201 dbSNP
rs975211512 1205 dbSNP
rs1192210185 1211 dbSNP
rs574627799 1215 dbSNP
rs920705317 1216 dbSNP
rs921326047 1217 dbSNP
rs1249649520 1227 dbSNP
rs767887165 1235 dbSNP
rs1461017268 1236 dbSNP
rs145654786 1249 dbSNP
rs1382864417 1251 dbSNP
rs1338029515 1256 dbSNP
rs989634217 1269 dbSNP
rs1229421397 1273 dbSNP
rs151039378 1276 dbSNP
rs1320302050 1280 dbSNP
rs1313343763 1282 dbSNP
rs945617246 1284 dbSNP
rs1381534473 1290 dbSNP
rs1336842479 1303 dbSNP
rs1221217858 1308 dbSNP
rs1041418736 1310 dbSNP
rs906872988 1314 dbSNP
rs372069008 1315 dbSNP
rs1391829573 1318 dbSNP
rs1161401659 1323 dbSNP
rs11880201 1327 dbSNP
rs1243917967 1329 dbSNP
rs1189709737 1339 dbSNP
rs894213919 1343 dbSNP
rs949933169 1344 dbSNP
rs200507175 1346 dbSNP
rs1247544797 1347 dbSNP
rs1245637836 1348 dbSNP
rs575800296 1348 dbSNP
rs1027229600 1352 dbSNP
rs1333530485 1352 dbSNP
rs1358301040 1352 dbSNP
rs143394669 1352 dbSNP
rs546142544 1353 dbSNP
rs887063513 1359 dbSNP
rs1372280036 1363 dbSNP
rs1183557438 1364 dbSNP
rs1301082278 1364 dbSNP
rs1411448914 1365 dbSNP
rs1423162021 1369 dbSNP
rs1165274888 1370 dbSNP
rs1468772820 1371 dbSNP
rs1159650403 1373 dbSNP
rs564813811 1375 dbSNP
rs1363339253 1377 dbSNP
rs1182569402 1378 dbSNP
rs1390527357 1382 dbSNP
rs140858772 1383 dbSNP
rs1222397043 1385 dbSNP
rs375938284 1389 dbSNP
rs1406217660 1395 dbSNP
rs905501217 1398 dbSNP
rs1348057618 1400 dbSNP
rs975382469 1404 dbSNP
rs190833881 1410 dbSNP
rs1228245430 1411 dbSNP
rs1289411656 1413 dbSNP
rs1331635168 1414 dbSNP
rs183888372 1416 dbSNP
rs1267699077 1421 dbSNP
rs1461828768 1423 dbSNP
rs150166353 1433 dbSNP
rs1009981609 1434 dbSNP
rs1399206927 1440 dbSNP
rs1384466435 1447 dbSNP
rs1159230386 1448 dbSNP
rs568912570 1449 dbSNP
rs949768462 1452 dbSNP
rs1009546372 1454 dbSNP
rs1019214024 1459 dbSNP
rs1413938943 1462 dbSNP
rs533160129 1466 dbSNP
rs556070680 1471 dbSNP
rs1027694351 1472 dbSNP
rs952098624 1476 dbSNP
rs983562468 1482 dbSNP
rs1415804543 1483 dbSNP
rs907689889 1483 dbSNP
rs1330673097 1484 dbSNP
rs949932113 1486 dbSNP
rs981735507 1488 dbSNP
rs1222865790 1491 dbSNP
rs927240038 1492 dbSNP
rs1055368348 1493 dbSNP
rs1309114872 1498 dbSNP
rs369829180 1504 dbSNP
rs1319296924 1505 dbSNP
rs1054125328 1508 dbSNP
rs1404052543 1509 dbSNP
rs892838897 1513 dbSNP
rs1287977413 1514 dbSNP
rs1427805230 1522 dbSNP
rs568214225 1522 dbSNP
rs1185149545 1538 dbSNP
rs931054757 1538 dbSNP
rs534683828 1539 dbSNP
rs945787302 1541 dbSNP
rs1041472872 1542 dbSNP
rs552914983 1550 dbSNP
rs570204587 1554 dbSNP
rs1009082491 1560 dbSNP
rs1280561945 1562 dbSNP
rs564082340 1565 dbSNP
rs568140349 1569 dbSNP
rs1040995190 1570 dbSNP
rs1004025255 1571 dbSNP
rs779051936 1572 dbSNP
rs1336181352 1580 dbSNP
rs1233092297 1583 dbSNP
rs900748541 1583 dbSNP
rs996862492 1584 dbSNP
rs1027642072 1590 dbSNP
rs1409872609 1592 dbSNP
rs1269322987 1593 dbSNP
rs952047664 1594 dbSNP
rs901078019 1595 dbSNP
rs535534376 1599 dbSNP
rs1015028406 1600 dbSNP
rs1409997666 1605 dbSNP
rs1169785457 1614 dbSNP
rs1372886745 1620 dbSNP
rs8111260 1622 dbSNP
rs1307852349 1628 dbSNP
rs1357566522 1630 dbSNP
rs1314713041 1640 dbSNP
rs1229092848 1652 dbSNP
rs575741835 1662 dbSNP
rs187197829 1675 dbSNP
rs1296490378 1677 dbSNP
rs958641712 1678 dbSNP
rs1371656065 1680 dbSNP
rs990055415 1693 dbSNP
rs914221389 1708 dbSNP
rs1423058288 1713 dbSNP
rs1384999144 1718 dbSNP
rs1162598796 1735 dbSNP
rs1273264138 1738 dbSNP
rs1344409174 1751 dbSNP
rs1415373355 1754 dbSNP
rs1480276664 1762 dbSNP
rs945736394 1762 dbSNP
rs1252370121 1763 dbSNP
rs1041420991 1765 dbSNP
rs543410688 1766 dbSNP
rs191847853 1767 dbSNP
rs1323684655 1775 dbSNP
rs1304982188 1798 dbSNP
rs967301411 1799 dbSNP
rs1351649003 1800 dbSNP
rs944833484 1802 dbSNP
rs1403621007 1808 dbSNP
rs183036833 1809 dbSNP
rs1294448992 1810 dbSNP
rs1458115843 1815 dbSNP
rs928241371 1816 dbSNP
rs959610651 1820 dbSNP
rs1412050890 1832 dbSNP
rs1267953612 1835 dbSNP
rs1479396366 1835 dbSNP
rs1191499894 1836 dbSNP
rs1489594428 1840 dbSNP
rs1259115158 1842 dbSNP
rs1215324178 1846 dbSNP
rs1329991990 1846 dbSNP
rs900694905 1854 dbSNP
rs540942778 1855 dbSNP
rs1345381809 1860 dbSNP
rs1245700587 1863 dbSNP
rs1360312940 1864 dbSNP
rs1449558825 1867 dbSNP
rs112700531 1870 dbSNP
rs1286818549 1872 dbSNP
rs991147520 1875 dbSNP
rs1387752550 1880 dbSNP
rs1388787655 1884 dbSNP
rs1160683387 1885 dbSNP
rs1468186256 1893 dbSNP
rs915583895 1894 dbSNP
rs996422969 1907 dbSNP
rs561638511 1908 dbSNP
rs1465481579 1914 dbSNP
rs887747937 1924 dbSNP
rs1250006472 1930 dbSNP
rs1201792872 1933 dbSNP
rs573584494 1934 dbSNP
rs1014977565 1936 dbSNP
rs1407370406 1937 dbSNP
rs1321848089 1939 dbSNP
rs971503421 1940 dbSNP
rs543931269 1941 dbSNP
rs1433940017 1947 dbSNP
rs1003404486 1950 dbSNP
rs186961817 1951 dbSNP
rs140329716 1954 dbSNP
rs990003138 1957 dbSNP
rs914505504 1962 dbSNP
rs551197131 1963 dbSNP
rs1191447050 1965 dbSNP
rs966984888 1967 dbSNP
rs191800280 1968 dbSNP
rs1288863521 1971 dbSNP
rs1167677530 1974 dbSNP
rs1450339305 1978 dbSNP
rs1465120917 1986 dbSNP
rs35647910 1987 dbSNP
rs1010876391 1991 dbSNP
rs943787303 1994 dbSNP
rs548870238 1995 dbSNP
rs1251124069 2000 dbSNP
rs1229515931 2001 dbSNP
rs1193108175 2005 dbSNP
rs1299449049 2005 dbSNP
rs1339415698 2006 dbSNP
rs1369495829 2006 dbSNP
rs1397739303 2006 dbSNP
rs1491280987 2006 dbSNP
rs1161959121 2007 dbSNP
rs1189647019 2007 dbSNP
rs1206489343 2007 dbSNP
rs1207741778 2007 dbSNP
rs1251641191 2007 dbSNP
rs1290013265 2007 dbSNP
rs1355159365 2007 dbSNP
rs1394176341 2007 dbSNP
rs1417863824 2007 dbSNP
rs1484273771 2007 dbSNP
rs1491287920 2007 dbSNP
rs35118321 2007 dbSNP
rs767062046 2007 dbSNP
rs775151174 2007 dbSNP
rs1284293418 2008 dbSNP
rs1474054463 2011 dbSNP
rs1246268310 2013 dbSNP
rs1333473785 2018 dbSNP
rs1054766939 2019 dbSNP
rs1004156630 2020 dbSNP
rs1035151049 2021 dbSNP
rs1322748463 2023 dbSNP
rs1391646391 2024 dbSNP
rs1386579852 2025 dbSNP
rs959494625 2026 dbSNP
rs1183595291 2028 dbSNP
rs1313359026 2030 dbSNP
rs1198530254 2031 dbSNP
rs922099769 2031 dbSNP
rs1342252160 2032 dbSNP
rs1290234029 2033 dbSNP
rs1242510704 2038 dbSNP
rs1283432872 2039 dbSNP
rs893025058 2039 dbSNP
rs1228966485 2040 dbSNP
rs1329540411 2040 dbSNP
rs991041065 2040 dbSNP
rs1435403608 2043 dbSNP
rs1229887934 2044 dbSNP
rs932149636 2045 dbSNP
rs1265779257 2050 dbSNP
rs1049306872 2052 dbSNP
rs888031841 2053 dbSNP
rs920818429 2059 dbSNP
rs1159949635 2061 dbSNP
rs940961073 2063 dbSNP
rs1172501362 2064 dbSNP
rs145476011 2067 dbSNP
rs1248799134 2069 dbSNP
rs939777503 2071 dbSNP
rs1463240015 2072 dbSNP
rs907226419 2076 dbSNP
rs1246908218 2078 dbSNP
rs1208749869 2084 dbSNP
rs1331132970 2087 dbSNP
rs1186016065 2094 dbSNP
rs1002941715 2100 dbSNP
rs1034866745 2101 dbSNP
rs894281511 2112 dbSNP
rs1011374088 2122 dbSNP
rs1409955070 2128 dbSNP
rs932437554 2131 dbSNP
rs1433208514 2135 dbSNP
rs1021459658 2137 dbSNP
rs137917882 2138 dbSNP
rs1437454868 2148 dbSNP
rs1403987140 2160 dbSNP
rs1404402484 2167 dbSNP
rs1394243045 2168 dbSNP
rs1333385133 2172 dbSNP
rs182610390 2173 dbSNP
rs1019256761 2177 dbSNP
rs965434157 2178 dbSNP
rs1166471090 2185 dbSNP
rs1447302455 2185 dbSNP
rs975159841 2188 dbSNP
rs1229941681 2190 dbSNP
rs116921720 2192 dbSNP
rs902638418 2204 dbSNP
rs1328138945 2210 dbSNP
rs539627512 2215 dbSNP
rs932098599 2220 dbSNP
rs558347438 2221 dbSNP
rs1342193331 2225 dbSNP
rs1341189947 2226 dbSNP
rs1298685850 2228 dbSNP
rs909414050 2231 dbSNP
rs1377122475 2237 dbSNP
rs940910517 2239 dbSNP
rs1199271892 2241 dbSNP
rs1283636013 2242 dbSNP
rs1449431449 2244 dbSNP
rs895332528 2253 dbSNP
rs1306571320 2262 dbSNP
rs1012346004 2263 dbSNP
rs573496817 2266 dbSNP
rs1027885108 2272 dbSNP
rs1450908796 2274 dbSNP
rs1411035038 2275 dbSNP
rs1184854994 2301 dbSNP
rs547983413 2305 dbSNP
rs907179116 2306 dbSNP
rs755054418 2307 dbSNP
rs1176997637 2308 dbSNP
rs1379477900 2315 dbSNP
rs142465251 2318 dbSNP
rs1320094921 2322 dbSNP
rs1312116223 2323 dbSNP
rs894568981 2326 dbSNP
rs1011658760 2329 dbSNP
rs1381417500 2331 dbSNP
rs1021398894 2336 dbSNP
rs1371154836 2341 dbSNP
rs556104480 2346 dbSNP
rs1351527306 2348 dbSNP
rs73037241 2349 dbSNP
rs1019961088 2351 dbSNP
rs1463220065 2352 dbSNP
rs187742625 2353 dbSNP
rs75216761 2370 dbSNP
rs1163467331 2374 dbSNP
rs751509286 2377 dbSNP
rs932489662 2384 dbSNP
rs148192229 2390 dbSNP
rs1231811113 2392 dbSNP
rs1184013681 2393 dbSNP
rs915180304 2396 dbSNP
rs141170864 2400 dbSNP
rs983900329 2403 dbSNP
rs1272995035 2405 dbSNP
rs570491700 2412 dbSNP
rs909361790 2414 dbSNP
rs559870091 2426 dbSNP
rs940858361 2427 dbSNP
rs939320796 2428 dbSNP
rs1431644020 2437 dbSNP
rs1056492887 2440 dbSNP
rs1525 2441 dbSNP
rs1292636057 2443 dbSNP
rs1390834148 2444 dbSNP
rs895216771 2447 dbSNP
rs1527 2463 dbSNP
rs972313493 2464 dbSNP
rs1156642124 2467 dbSNP
rs1396074708 2475 dbSNP
rs377365994 2479 dbSNP
rs1456655715 2488 dbSNP
rs1412541120 2490 dbSNP
rs11459078 2497 dbSNP
rs1027770932 2498 dbSNP
rs1270648384 2498 dbSNP
rs535577501 2498 dbSNP
rs61272508 2498 dbSNP
rs368233007 2499 dbSNP
rs938659132 2499 dbSNP
rs1056198510 2500 dbSNP
rs558329966 2500 dbSNP
rs116675107 2501 dbSNP
rs562080707 2501 dbSNP
rs199865846 2502 dbSNP
rs529246971 2502 dbSNP
rs563154050 2503 dbSNP
rs8100998 2503 dbSNP
rs1056377632 2504 dbSNP
rs1368457510 2504 dbSNP
rs372907391 2504 dbSNP
rs1491530792 2505 dbSNP
rs745617297 2505 dbSNP
rs57658952 2506 dbSNP
rs1040927123 2507 dbSNP
rs1204046461 2507 dbSNP
rs1342378360 2507 dbSNP
rs539911335 2508 dbSNP
rs1294936076 2509 dbSNP
rs551907002 2510 dbSNP
rs567029877 2511 dbSNP
rs534435192 2513 dbSNP
rs1313424616 2516 dbSNP
rs887958927 2534 dbSNP
rs1005431523 2539 dbSNP
rs1297743213 2550 dbSNP
rs901082222 2562 dbSNP
rs1430658061 2563 dbSNP
rs1398820709 2567 dbSNP
rs1161672622 2571 dbSNP
rs753741215 2571 dbSNP
rs1369103541 2573 dbSNP
rs1231299528 2576 dbSNP
rs1295961530 2580 dbSNP
rs996809337 2590 dbSNP
rs1028394370 2603 dbSNP
rs1471875508 2608 dbSNP
rs779898535 2609 dbSNP
rs952381742 2610 dbSNP
rs570373147 2611 dbSNP
rs1438054178 2612 dbSNP
rs748936229 2613 dbSNP
rs555782242 2622 dbSNP
rs574310609 2635 dbSNP
rs1355098710 2636 dbSNP
rs962172052 2640 dbSNP
rs1487653104 2644 dbSNP
rs1273226503 2647 dbSNP
rs972646549 2648 dbSNP
rs773857075 2654 dbSNP
rs953657005 2656 dbSNP
rs762234902 2658 dbSNP
rs960563878 2666 dbSNP
rs1006654835 2667 dbSNP
rs536997988 2668 dbSNP
rs915886537 2671 dbSNP
rs1386392080 2676 dbSNP
rs947401870 2677 dbSNP
rs373822419 2678 dbSNP
rs772531249 2686 dbSNP
rs1043087430 2687 dbSNP
rs185669491 2692 dbSNP
rs978311424 2699 dbSNP
rs1411789373 2701 dbSNP
rs924699736 2706 dbSNP
rs923910134 2713 dbSNP
rs960603787 2724 dbSNP
rs992159119 2726 dbSNP
rs1450635777 2729 dbSNP
rs1253095900 2730 dbSNP
rs1214939573 2733 dbSNP
rs934799998 2747 dbSNP
rs1267488334 2750 dbSNP
rs1224248016 2757 dbSNP
rs1418629487 2759 dbSNP
rs1352618861 2762 dbSNP
rs556097652 2763 dbSNP
rs948022047 2775 dbSNP
rs577570454 2776 dbSNP
rs1433076519 2786 dbSNP
rs190544562 2787 dbSNP
rs1347870122 2794 dbSNP
rs761078753 2801 dbSNP
rs1402920392 2809 dbSNP
rs1320752484 2813 dbSNP
rs940891369 2814 dbSNP
rs1390210748 2817 dbSNP
rs1432191898 2818 dbSNP
rs553493344 2819 dbSNP
rs888084433 2825 dbSNP
rs1447185872 2827 dbSNP
rs193077292 2834 dbSNP
rs1005231496 2840 dbSNP
rs542444765 2845 dbSNP
rs567617784 2846 dbSNP
rs1305972831 2850 dbSNP
rs1226433130 2853 dbSNP
rs902128507 2864 dbSNP
rs561006774 2866 dbSNP
rs997773338 2878 dbSNP
rs961417993 2881 dbSNP
rs1050634840 2885 dbSNP
rs1357865233 2885 dbSNP
rs1334078080 2889 dbSNP
rs1232927606 2894 dbSNP
rs1003330256 2895 dbSNP
rs889469673 2905 dbSNP
rs1377627197 2913 dbSNP
rs1175165885 2919 dbSNP
rs1006540341 2925 dbSNP
rs1389039635 2927 dbSNP
rs1186538108 2933 dbSNP
rs868601348 2934 dbSNP
rs1466317363 2938 dbSNP
rs539538485 2941 dbSNP
rs1485905805 2942 dbSNP
rs960250938 2943 dbSNP
rs74381372 2946 dbSNP
rs916168002 2954 dbSNP
rs968658678 2962 dbSNP
rs1411384036 2966 dbSNP
rs543372233 2967 dbSNP
rs999401256 2969 dbSNP
rs144797345 2977 dbSNP
rs1159464371 2979 dbSNP
rs934723666 2983 dbSNP
rs533373097 2992 dbSNP
rs1455314510 2999 dbSNP
rs2060272 3000 dbSNP
rs1162633227 3001 dbSNP
rs1475471784 3009 dbSNP
rs932519491 3013 dbSNP
rs1449432841 3014 dbSNP
rs1179662790 3015 dbSNP
rs1049633129 3016 dbSNP
rs1233721755 3017 dbSNP
rs888371060 3018 dbSNP
rs1023477322 3020 dbSNP
rs969376852 3022 dbSNP
rs1289358242 3023 dbSNP
rs1337515061 3026 dbSNP
rs567017718 3028 dbSNP
rs1409675783 3030 dbSNP
rs1222245612 3031 dbSNP
rs1283711284 3033 dbSNP
rs1298441892 3037 dbSNP
rs1312797600 3039 dbSNP
rs546299189 3045 dbSNP
rs1443885682 3047 dbSNP
rs1347644452 3048 dbSNP
rs1156839024 3051 dbSNP
rs1212190987 3051 dbSNP
rs1420018618 3051 dbSNP
rs1461898087 3051 dbSNP
rs111798921 3052 dbSNP
rs1160941677 3052 dbSNP
rs1246232366 3052 dbSNP
rs1318503434 3052 dbSNP
rs1345585246 3052 dbSNP
rs1394781417 3052 dbSNP
rs1396002832 3052 dbSNP
rs1431666784 3052 dbSNP
rs1441078828 3052 dbSNP
rs1452916040 3052 dbSNP
rs1455678221 3052 dbSNP
rs1464004621 3052 dbSNP
rs59596478 3052 dbSNP
rs74178080 3052 dbSNP
rs985176759 3052 dbSNP
rs1486452961 3054 dbSNP
rs1235607883 3056 dbSNP
rs1208546565 3057 dbSNP
rs1485297209 3057 dbSNP
rs1311959264 3058 dbSNP
rs1372574955 3058 dbSNP
rs909325238 3058 dbSNP
rs1290561145 3059 dbSNP
rs1362487115 3059 dbSNP
rs1381591873 3059 dbSNP
rs1192492001 3060 dbSNP
rs1388422153 3060 dbSNP
rs1464409908 3060 dbSNP
rs1429634593 3061 dbSNP
rs940761166 3061 dbSNP
rs954010989 3061 dbSNP
rs1271861233 3062 dbSNP
rs1354616510 3062 dbSNP
rs1410874594 3063 dbSNP
rs1475137361 3063 dbSNP
rs868858093 3063 dbSNP
rs1252518261 3064 dbSNP
rs1475416892 3064 dbSNP
rs1242545172 3065 dbSNP
rs1348369463 3065 dbSNP
rs1007172952 3066 dbSNP
rs757274056 3066 dbSNP
rs1180689416 3067 dbSNP
rs1366925822 3067 dbSNP
rs866114145 3068 dbSNP
rs923443647 3068 dbSNP
rs1215449401 3069 dbSNP
rs1273788550 3069 dbSNP
rs1278684964 3070 dbSNP
rs933448750 3070 dbSNP
rs1240040046 3071 dbSNP
rs1253669767 3071 dbSNP
rs1337686174 3071 dbSNP
rs1440332535 3072 dbSNP
rs1395286869 3073 dbSNP
rs1471435433 3073 dbSNP
rs111756852 3074 dbSNP
rs1159452213 3074 dbSNP
rs1372524356 3074 dbSNP
rs1338238386 3075 dbSNP
rs1408489384 3075 dbSNP
rs1365251890 3076 dbSNP
rs1191348066 3077 dbSNP
rs1157586691 3078 dbSNP
rs941290315 3079 dbSNP
rs1215509144 3084 dbSNP
rs1253035246 3084 dbSNP
rs1425303309 3084 dbSNP
rs1050686289 3085 dbSNP
rs1036694116 3092 dbSNP
rs1352552605 3093 dbSNP
rs1278522733 3098 dbSNP
rs942411517 3100 dbSNP
rs896840376 3106 dbSNP
rs1305664939 3110 dbSNP
rs1043776250 3114 dbSNP
rs1326287646 3116 dbSNP
rs73551844 3117 dbSNP
rs1402869267 3119 dbSNP
rs1034797296 3121 dbSNP
rs1171394853 3129 dbSNP
rs1433661327 3130 dbSNP
rs1395172830 3131 dbSNP
rs895934668 3135 dbSNP
rs903641439 3137 dbSNP
rs1013048123 3140 dbSNP
rs1193778891 3145 dbSNP
rs1030674282 3150 dbSNP
rs1255092313 3152 dbSNP
rs1210470096 3160 dbSNP
rs1348804821 3171 dbSNP
rs1023124972 3175 dbSNP
rs1212951241 3183 dbSNP
rs1440318384 3185 dbSNP
rs1279145698 3196 dbSNP
rs571902671 3203 dbSNP
rs979007038 3207 dbSNP
rs1221071164 3209 dbSNP
rs1278277118 3215 dbSNP
rs868283295 3216 dbSNP
rs1347108197 3218 dbSNP
rs549521560 3221 dbSNP
rs1205755062 3222 dbSNP
rs1312590056 3225 dbSNP
rs567785891 3228 dbSNP
rs28562071 3239 dbSNP
rs1276533601 3242 dbSNP
rs1032076543 3244 dbSNP
rs569608851 3247 dbSNP
rs1168458587 3254 dbSNP
rs969262347 3267 dbSNP
rs1255157583 3269 dbSNP
rs977218656 3271 dbSNP
rs1478800919 3274 dbSNP
rs557015429 3275 dbSNP
rs57882551 3275 dbSNP
rs984840881 3275 dbSNP
rs556590313 3276 dbSNP
rs962039478 3285 dbSNP
rs1393924708 3289 dbSNP
rs1333245393 3293 dbSNP
rs972573201 3295 dbSNP
rs1357732008 3301 dbSNP
rs1304266857 3303 dbSNP
rs139935598 3306 dbSNP
rs933501237 3310 dbSNP
rs986285713 3310 dbSNP
rs538296188 3312 dbSNP
rs1164114468 3313 dbSNP
rs985282185 3314 dbSNP
rs909754247 3316 dbSNP
rs947623728 3319 dbSNP
rs1408507443 3321 dbSNP
rs1469765315 3325 dbSNP
rs1233528732 3329 dbSNP
rs941237951 3336 dbSNP
rs1043275858 3338 dbSNP
rs1036976967 3340 dbSNP
rs1467181200 3350 dbSNP
rs903525496 3356 dbSNP
rs896793751 3357 dbSNP
rs939035175 3358 dbSNP
rs1337441059 3359 dbSNP
rs1056584715 3364 dbSNP
rs894888536 3365 dbSNP
rs1011992235 3369 dbSNP
rs1023071160 3375 dbSNP
rs904729993 3376 dbSNP
rs1372083101 3378 dbSNP
rs553431932 3380 dbSNP
rs1448426889 3381 dbSNP
rs1031941381 3385 dbSNP
rs896220095 3385 dbSNP
rs956194694 3388 dbSNP
rs1325187575 3394 dbSNP
rs976786841 3422 dbSNP
rs1351416764 3423 dbSNP
rs1013399556 3425 dbSNP
rs1023414898 3426 dbSNP
rs905145446 3431 dbSNP
rs1195073610 3433 dbSNP
rs1006561005 3434 dbSNP
rs1016156706 3434 dbSNP
rs368325472 3434 dbSNP
rs1030109170 3443 dbSNP
rs1215611941 3444 dbSNP
rs1317882944 3444 dbSNP
rs1241831310 3445 dbSNP
rs1284580585 3445 dbSNP
rs962372517 3445 dbSNP
rs1441549074 3446 dbSNP
rs1369722054 3449 dbSNP
rs1287028862 3450 dbSNP
rs993497268 3453 dbSNP
rs954106894 3457 dbSNP
rs1160712682 3461 dbSNP
rs1433037100 3465 dbSNP
rs1030450529 3467 dbSNP
rs954770707 3471 dbSNP
rs377050408 3472 dbSNP
rs571840569 3476 dbSNP
rs542326492 3482 dbSNP
rs968880434 3492 dbSNP
rs909701793 3493 dbSNP
rs865791568 3494 dbSNP
rs972607884 3501 dbSNP
rs1189780843 3505 dbSNP
rs979436751 3508 dbSNP
rs184640973 3510 dbSNP
rs924863578 3511 dbSNP
rs1345208843 3519 dbSNP
rs918520709 3526 dbSNP
rs935014488 3530 dbSNP
rs1167737509 3537 dbSNP
rs1234452365 3540 dbSNP
rs1313417705 3546 dbSNP
rs1414948397 3553 dbSNP
rs11881791 3562 dbSNP
rs1324084186 3564 dbSNP
rs1056131400 3575 dbSNP
rs916256648 3576 dbSNP
rs1299750206 3581 dbSNP
rs1413174699 3583 dbSNP
rs1375142468 3587 dbSNP
rs1174484213 3597 dbSNP
rs947793892 3599 dbSNP
rs576159048 3605 dbSNP
rs543659210 3606 dbSNP
rs1170403506 3611 dbSNP
rs949134112 3612 dbSNP
rs189146459 3615 dbSNP
rs145291188 3616 dbSNP
rs1211117364 3618 dbSNP
rs545446110 3624 dbSNP
rs1358144925 3627 dbSNP
rs1231108269 3636 dbSNP
rs897730147 3637 dbSNP
rs1307939863 3638 dbSNP
rs181127852 3639 dbSNP
rs765244630 3643 dbSNP
rs1030335988 3648 dbSNP
rs954655348 3657 dbSNP
rs1464968010 3661 dbSNP
rs1007656370 3667 dbSNP
rs1394451774 3667 dbSNP
rs201476366 3673 dbSNP
rs142464577 3675 dbSNP
rs1462555123 3694 dbSNP
rs969308855 3698 dbSNP
rs1445821889 3699 dbSNP
rs978933100 3706 dbSNP
rs1187839497 3713 dbSNP
rs1247811099 3716 dbSNP
rs924883728 3716 dbSNP
rs1194801078 3717 dbSNP
rs1457812909 3722 dbSNP
rs892038833 3727 dbSNP
rs998880825 3732 dbSNP
rs956306856 3733 dbSNP
rs1333935084 3734 dbSNP
rs1238442349 3736 dbSNP
rs987803380 3738 dbSNP
rs1247281281 3740 dbSNP
rs1029643685 3745 dbSNP
rs1334270055 3746 dbSNP
rs917583984 3752 dbSNP
rs954053167 3753 dbSNP
rs1392081910 3757 dbSNP
rs949030131 3758 dbSNP
rs1324507485 3772 dbSNP
rs6508865 3774 dbSNP
rs926376450 3775 dbSNP
rs941888986 3780 dbSNP
rs1037533398 3782 dbSNP
rs1361763312 3784 dbSNP
rs1017035145 3785 dbSNP
rs897776453 3794 dbSNP
rs1439816032 3796 dbSNP
rs962505581 3797 dbSNP
rs1191696293 3799 dbSNP
rs1467933461 3800 dbSNP
rs1290497009 3802 dbSNP
rs1211473833 3803 dbSNP
rs549214455 3813 dbSNP
rs918457631 3814 dbSNP
rs1260397765 3815 dbSNP
rs1241095473 3816 dbSNP
rs960639907 3819 dbSNP
rs567808028 3821 dbSNP
rs531853336 3829 dbSNP
rs1007541754 3831 dbSNP
rs1384660697 3832 dbSNP
rs916220022 3833 dbSNP
rs1018127986 3837 dbSNP
rs761019456 3841 dbSNP
rs1409875608 3848 dbSNP
rs550449412 3851 dbSNP
rs35726280 3860 dbSNP
rs1342046866 3868 dbSNP
rs1247265668 3881 dbSNP
rs1200868233 3883 dbSNP
rs1000803942 3885 dbSNP
rs185731941 3890 dbSNP
rs956166723 3891 dbSNP
rs1292443700 3899 dbSNP
rs993046014 3901 dbSNP
rs1233738478 3904 dbSNP
rs766850009 3907 dbSNP
rs1277159655 3909 dbSNP
rs925041475 3910 dbSNP
rs1319328653 3912 dbSNP
rs1326236291 3912 dbSNP
rs142291327 3913 dbSNP
rs1362125863 3915 dbSNP
rs926401484 3918 dbSNP
rs1310673967 3921 dbSNP
rs1053287153 3922 dbSNP
rs891981929 3930 dbSNP
rs146747328 3933 dbSNP
rs1174267929 3934 dbSNP
rs1474352411 3935 dbSNP
rs1372292549 3936 dbSNP
rs1051795053 3937 dbSNP
rs1489141811 3939 dbSNP
rs1257402498 3948 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084040. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep1 HITS-CLIP data was present in GSM1084041. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep1 HITS-CLIP data was present in GSM1084042. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep2 HITS-CLIP data was present in GSM1084043. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep2 ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084040
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep1
Location of target site ENST00000599794.1 | 3UTR | AGGCUGAGGUGGGUGGAUCACCUGAGGUCAGGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084041
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep1
Location of target site ENST00000599794.1 | 3UTR | GGAGGCUGAGGUGGGUGGAUCACCUGAGGUCAGGAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084042
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep2
Location of target site ENST00000599794.1 | 3UTR | GGAGGCUGAGGUGGGUGGAUCACCUGAGGUCAGGAGUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1084043
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep2
Location of target site ENST00000599794.1 | 3UTR | GGGAGGCUGAGGUGGGUGGAUCACCUGAGGUCAGGAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
133 hsa-miR-4680-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT378771 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT393867 ZDHHC21 zinc finger DHHC-type containing 21 2 4
MIRT446684 C2CD2 C2 calcium dependent domain containing 2 2 2
MIRT447600 MRPL3 mitochondrial ribosomal protein L3 2 2
MIRT450708 RNF152 ring finger protein 152 2 2
MIRT450784 PAPOLG poly(A) polymerase gamma 2 2
MIRT454623 COL23A1 collagen type XXIII alpha 1 chain 2 8
MIRT461620 PTCD3 pentatricopeptide repeat domain 3 2 2
MIRT462695 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT475530 HOXA3 homeobox A3 2 8
MIRT475739 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 2 4
MIRT489676 CYP1A1 cytochrome P450 family 1 subfamily A member 1 2 2
MIRT490610 SLC47A1 solute carrier family 47 member 1 2 2
MIRT493628 HIC2 HIC ZBTB transcriptional repressor 2 2 2
MIRT496152 RPS15A ribosomal protein S15a 2 2
MIRT499232 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT501496 PRICKLE2 prickle planar cell polarity protein 2 2 2
MIRT507163 GAS2L3 growth arrest specific 2 like 3 2 2
MIRT512389 MTRNR2L1 MT-RNR2-like 1 2 4
MIRT514626 MTRNR2L7 MT-RNR2-like 7 2 2
MIRT517474 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT525332 CNGB1 cyclic nucleotide gated channel beta 1 2 2
MIRT526685 BAK1 BCL2 antagonist/killer 1 2 2
MIRT527317 CCR2 C-C motif chemokine receptor 2 2 2
MIRT527608 EYS eyes shut homolog (Drosophila) 2 2
MIRT528794 RAB32 RAB32, member RAS oncogene family 2 2
MIRT531048 TIPARP TCDD inducible poly(ADP-ribose) polymerase 2 2
MIRT532254 TBPL2 TATA-box binding protein like 2 2 2
MIRT533801 TMED7 transmembrane p24 trafficking protein 7 2 4
MIRT535887 MLEC malectin 2 2
MIRT540704 PDPK1 3-phosphoinositide dependent protein kinase 1 2 4
MIRT544645 PHF8 PHD finger protein 8 2 4
MIRT545760 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT555310 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 2
MIRT555877 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 4
MIRT559507 ARID5B AT-rich interaction domain 5B 2 2
MIRT560448 SLC30A7 solute carrier family 30 member 7 2 2
MIRT561262 ZIK1 zinc finger protein interacting with K protein 1 2 2
MIRT561795 PAWR pro-apoptotic WT1 regulator 2 2
MIRT567007 KLHL15 kelch like family member 15 2 2
MIRT569298 SURF6 surfeit 6 2 2
MIRT570606 MTRNR2L11 MT-RNR2-like 11 2 2
MIRT572888 ADCY2 adenylate cyclase 2 2 2
MIRT573119 ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 2 2
MIRT608332 ZNF670 zinc finger protein 670 2 6
MIRT614942 KCNK5 potassium two pore domain channel subfamily K member 5 2 2
MIRT615324 ERN1 endoplasmic reticulum to nucleus signaling 1 2 2
MIRT618441 ZNF800 zinc finger protein 800 2 2
MIRT620110 HARBI1 harbinger transposase derived 1 2 2
MIRT626008 ZNF517 zinc finger protein 517 2 2
MIRT626626 SLC30A6 solute carrier family 30 member 6 2 2
MIRT627842 POU3F1 POU class 3 homeobox 1 2 2
MIRT628386 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 2 2
MIRT629305 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT629864 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT630444 IDE insulin degrading enzyme 2 2
MIRT631854 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT633173 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT633477 ZNF724P zinc finger protein 724 2 2
MIRT634395 PLSCR1 phospholipid scramblase 1 2 2
MIRT635538 TRIM72 tripartite motif containing 72 2 2
MIRT635821 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT636169 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT636797 CYB5D1 cytochrome b5 domain containing 1 2 2
MIRT637952 IVD isovaleryl-CoA dehydrogenase 2 2
MIRT645136 HES2 hes family bHLH transcription factor 2 2 2
MIRT645667 ADK adenosine kinase 2 2
MIRT646148 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT647004 NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 2 2
MIRT648187 C2orf68 chromosome 2 open reading frame 68 2 2
MIRT650090 TERF2 telomeric repeat binding factor 2 2 2
MIRT650329 RTN2 reticulon 2 2 2
MIRT654224 RNF165 ring finger protein 165 2 2
MIRT654545 RAB1A RAB1A, member RAS oncogene family 2 2
MIRT656457 MAPK14 mitogen-activated protein kinase 14 2 2
MIRT656828 KLF8 Kruppel like factor 8 2 2
MIRT657112 ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein like 2 2 2
MIRT657930 GATSL2 cytosolic arginine sensor for mTORC1 subunit 2 2 2
MIRT659375 CREG2 cellular repressor of E1A stimulated genes 2 2 2
MIRT659833 CARHSP1 calcium regulated heat stable protein 1 2 2
MIRT662108 LACTB lactamase beta 2 4
MIRT662789 TBC1D25 TBC1 domain family member 25 2 2
MIRT669501 ARL3 ADP ribosylation factor like GTPase 3 2 2
MIRT669759 ZNF101 zinc finger protein 101 2 4
MIRT669800 GAN gigaxonin 2 2
MIRT670050 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT670299 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT670388 EMP2 epithelial membrane protein 2 2 2
MIRT672862 C22orf29 retrotransposon Gag like 10 2 2
MIRT672890 FXN frataxin 2 2
MIRT673210 C10orf76 chromosome 10 open reading frame 76 2 2
MIRT674001 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT674163 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 2 2
MIRT674502 TIRAP TIR domain containing adaptor protein 2 2
MIRT675470 NUBPL nucleotide binding protein like 2 2
MIRT675671 TMOD2 tropomodulin 2 2 2
MIRT676006 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT676074 TIMM50 translocase of inner mitochondrial membrane 50 2 2
MIRT676386 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT676764 SNX2 sorting nexin 2 2 2
MIRT676896 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT676978 ZNF708 zinc finger protein 708 2 2
MIRT677236 C15orf40 chromosome 15 open reading frame 40 2 2
MIRT677369 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT677464 PDLIM3 PDZ and LIM domain 3 2 2
MIRT678081 EIF2A eukaryotic translation initiation factor 2A 2 2
MIRT678093 ATCAY ATCAY, caytaxin 2 2
MIRT678324 FBLIM1 filamin binding LIM protein 1 2 2
MIRT678417 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678521 ZNF347 zinc finger protein 347 2 2
MIRT678700 TRIP11 thyroid hormone receptor interactor 11 2 2
MIRT678829 PDE6A phosphodiesterase 6A 2 2
MIRT679991 RUNDC1 RUN domain containing 1 2 2
MIRT680751 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT681249 ZNF383 zinc finger protein 383 2 2
MIRT681422 GTF3C6 general transcription factor IIIC subunit 6 2 2
MIRT681948 SLC19A3 solute carrier family 19 member 3 2 2
MIRT689278 C5AR2 complement component 5a receptor 2 2 2
MIRT690389 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT691845 OSCAR osteoclast associated, immunoglobulin-like receptor 2 2
MIRT693863 IYD iodotyrosine deiodinase 2 2
MIRT696002 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT701930 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT702341 KLHL7 kelch like family member 7 2 2
MIRT703557 FKBP14 FK506 binding protein 14 2 2
MIRT705033 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT706341 STAC2 SH3 and cysteine rich domain 2 2 2
MIRT709671 RGP1 RGP1 homolog, RAB6A GEF complex partner 1 2 2
MIRT711212 EFHB EF-hand domain family member B 2 2
MIRT718342 PURA purine rich element binding protein A 2 2
MIRT722755 SIRPB2 signal regulatory protein beta 2 2 2
MIRT723535 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 2 2
MIRT724498 BFAR bifunctional apoptosis regulator 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4680-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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