pre-miRNA Information
pre-miRNA hsa-mir-4708   
Genomic Coordinates chr14: 65335117 - 65335183
Description Homo sapiens miR-4708 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4708-5p
Sequence 9| AGAGAUGCCGCCUUGCUCCUU |29
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1017378847 9 dbSNP
rs750825813 10 dbSNP
rs1297395738 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol IL10RB   
Synonyms CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2
Description interleukin 10 receptor subunit beta
Transcript NM_000628   
Expression
Putative miRNA Targets on IL10RB
3'UTR of IL10RB
(miRNA target sites are highlighted)
>IL10RB|NM_000628|3'UTR
   1 GCTCTGAGAAGGAAACACACTCGGCTGGGCACAGTGACGTACTCCATCTCACATCTGCCTCAGTGAGGGATCAGGGCAGC
  81 AAACAAGGGCCAAGACCATCTGAGCCAGCCCCACATCTAGAACTCCCAGACCCTGGACTTAGCCACCAGAGAGCTACATT
 161 TTAAAGGCTGTCTTGGCAAAAATACTCCATTTGGGAACTCACTGCCTTATAAAGGCTTTCATGATGTTTTCAGAAGTTGG
 241 CCACTGAGAGTGTAATTTTCAGCCTTTTATATCACTAAAATAAGATCATGTTTTAATTGTGAGAAACAGGGCCGAGCACA
 321 GTGGCTCACGCCTGTAATACCAGCACCTTAGAGGTCGAGGCAGGCGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTG
 401 GCCAATATGGTGAAACCCAGTCTCTACTAAAAATACAAAAATTAGCTAGGCATGATGGCGCATGCCTATAATCCCAGCTA
 481 CTCGAGTGCCTGAGGCAGGAGAATTGCATGAACCCGGGAGGAGGAGGAGGAGGTTGCAGTGAGCCGAGATAGCGGCACTG
 561 CACTCCAGCCTGGGTGACAAAGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAATTGTGAGAAACAGAAATACTTAAA
 641 ATGAGGAATAAGAATGGAGATGTTACATCTGGTAGATGTAACATTCTACCAGATTATGGATGGACTGATCTGAAAATCGA
 721 CCTCAACTCAAGGGTGGTCAGCTCAATGCTACACAGAGCACGGACTTTTGGATTCTTTGCAGTACTTTGAATTTATTTTT
 801 CTACCTATATATGTTTTATATGCTGCTGGTGCTCCATTAAAGTTTTACTCTGTGTTGCACTATATGTGTTCATGATAAAA
 881 AA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' uuccUCGUUCCGCCGUAGAGa 5'
              ||::|| |  |||||| 
Target 5' acaaAGTGAGACTCCATCTCa 3'
577 - 597 129.00 -8.90
2
miRNA  3' uuccucguuccgccGUAGAGa 5'
                        |||||| 
Target 5' acagtgacgtactcCATCTCa 3'
31 - 51 120.00 -7.90
3
miRNA  3' uuCCUCGUUCCGCCGUAGAga 5'
            ||: |||| |  |||||  
Target 5' aaGGGCCAAGAC--CATCTga 3'
85 - 103 114.00 -11.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
339696 18 ClinVar
339697 21 ClinVar
339698 86 ClinVar
339699 136 ClinVar
339700 315 ClinVar
339701 335 ClinVar
339702 366 ClinVar
339703 516 ClinVar
898189 520 ClinVar
898190 537 ClinVar
339704 547 ClinVar
339705 593 ClinVar
339706 597 ClinVar
339707 597 ClinVar
339708 617 ClinVar
339709 720 ClinVar
339710 762 ClinVar
339711 797 ClinVar
339712 817 ClinVar
COSN30158865 7 COSMIC
COSN26980280 40 COSMIC
COSN19638573 86 COSMIC
COSN21638571 160 COSMIC
COSN20116839 616 COSMIC
COSN5769006 818 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs764763018 3 dbSNP
rs1058862 4 dbSNP
rs768456830 11 dbSNP
rs776455147 12 dbSNP
rs886057003 18 dbSNP
rs748094483 20 dbSNP
rs886057004 21 dbSNP
rs1411265459 23 dbSNP
rs769497995 24 dbSNP
rs1344398296 25 dbSNP
rs772836914 26 dbSNP
rs762495022 28 dbSNP
rs770320812 31 dbSNP
rs1324552854 33 dbSNP
rs1367054135 34 dbSNP
rs1407573412 37 dbSNP
rs376104508 39 dbSNP
rs760973106 40 dbSNP
rs764500130 43 dbSNP
rs1282430304 52 dbSNP
rs139413536 55 dbSNP
rs754344615 60 dbSNP
rs757755568 62 dbSNP
rs765354572 64 dbSNP
rs750510923 65 dbSNP
rs1037746312 66 dbSNP
rs758406164 67 dbSNP
rs1251314168 69 dbSNP
rs780170183 75 dbSNP
rs747203732 78 dbSNP
rs1367248778 80 dbSNP
rs1472717655 85 dbSNP
rs3171425 86 dbSNP
rs752012391 89 dbSNP
rs1428197191 91 dbSNP
rs781038420 92 dbSNP
rs1370782266 93 dbSNP
rs748094856 96 dbSNP
rs11701888 101 dbSNP
rs1392688554 105 dbSNP
rs1331563344 109 dbSNP
rs1339812072 113 dbSNP
rs1245362472 121 dbSNP
rs555064260 124 dbSNP
rs773217539 125 dbSNP
rs1227384022 127 dbSNP
rs1014684753 130 dbSNP
rs1274262628 133 dbSNP
rs8178561 136 dbSNP
rs1197632770 142 dbSNP
rs770520463 145 dbSNP
rs1442374041 154 dbSNP
rs1316731866 159 dbSNP
rs1188912110 169 dbSNP
rs773927781 170 dbSNP
rs1448120476 177 dbSNP
rs1168342930 186 dbSNP
rs1266894465 187 dbSNP
rs1390422771 188 dbSNP
rs1360523173 210 dbSNP
rs1315437064 221 dbSNP
rs998948453 239 dbSNP
rs1245038972 244 dbSNP
rs1380338985 246 dbSNP
rs1271819947 250 dbSNP
rs1431400465 253 dbSNP
rs528482502 254 dbSNP
rs1183286713 258 dbSNP
rs1315685364 259 dbSNP
rs879575028 270 dbSNP
rs540281964 271 dbSNP
rs895990590 272 dbSNP
rs367791594 280 dbSNP
rs561856540 282 dbSNP
rs1033176483 285 dbSNP
rs1474480268 290 dbSNP
rs1010872768 302 dbSNP
rs768254301 308 dbSNP
rs1415244544 312 dbSNP
rs968371077 314 dbSNP
rs8178562 315 dbSNP
rs1240415249 326 dbSNP
rs1201145141 330 dbSNP
rs547091893 331 dbSNP
rs377255448 335 dbSNP
rs976825221 339 dbSNP
rs1356927270 345 dbSNP
rs1193682242 354 dbSNP
rs1353340156 358 dbSNP
rs886057005 366 dbSNP
rs1361273352 367 dbSNP
rs1267861730 371 dbSNP
rs1406290672 376 dbSNP
rs1345618689 379 dbSNP
rs1049953624 380 dbSNP
rs922388447 398 dbSNP
rs1358430561 402 dbSNP
rs1402721851 406 dbSNP
rs8178563 409 dbSNP
rs1356581545 416 dbSNP
rs1171630034 428 dbSNP
rs951238586 434 dbSNP
rs1409866474 447 dbSNP
rs1418052617 451 dbSNP
rs1212272861 458 dbSNP
rs982539338 460 dbSNP
rs565409482 461 dbSNP
rs1197470463 467 dbSNP
rs909840172 469 dbSNP
rs941192221 472 dbSNP
rs1055607059 483 dbSNP
rs1234394154 484 dbSNP
rs942016190 485 dbSNP
rs1306821660 494 dbSNP
rs753604899 498 dbSNP
rs915838740 500 dbSNP
rs1255034013 510 dbSNP
rs1282103200 513 dbSNP
rs1323537387 513 dbSNP
rs767017864 516 dbSNP
rs1037693917 517 dbSNP
rs1353156339 517 dbSNP
rs1375157377 517 dbSNP
rs1339192870 520 dbSNP
rs569425734 522 dbSNP
rs1187335838 525 dbSNP
rs1238537505 528 dbSNP
rs1421077738 530 dbSNP
rs1474074081 535 dbSNP
rs750248101 537 dbSNP
rs937385468 542 dbSNP
rs886057006 547 dbSNP
rs533712176 554 dbSNP
rs1170700850 555 dbSNP
rs1261962052 559 dbSNP
rs1373943170 560 dbSNP
rs552117374 562 dbSNP
rs1318221409 563 dbSNP
rs1307216233 566 dbSNP
rs1395203351 571 dbSNP
rs1371561662 572 dbSNP
rs1317681447 574 dbSNP
rs566444657 575 dbSNP
rs1342140767 577 dbSNP
rs1428590595 579 dbSNP
rs1455363596 579 dbSNP
rs1345890486 590 dbSNP
rs1158567432 592 dbSNP
rs1417570169 593 dbSNP
rs886057007 593 dbSNP
rs1378234347 596 dbSNP
rs1445135350 596 dbSNP
rs1491300229 596 dbSNP
rs1172878023 597 dbSNP
rs1214619149 597 dbSNP
rs1247240678 597 dbSNP
rs1257223135 597 dbSNP
rs1491208550 597 dbSNP
rs201799934 597 dbSNP
rs5843596 597 dbSNP
rs886057008 597 dbSNP
rs1342237764 599 dbSNP
rs1057226678 613 dbSNP
rs886057009 617 dbSNP
rs1346762335 618 dbSNP
rs1200186510 619 dbSNP
rs1279815866 621 dbSNP
rs893200564 622 dbSNP
rs1444565422 628 dbSNP
rs1191686798 629 dbSNP
rs1007687666 647 dbSNP
rs1288422726 653 dbSNP
rs1017685694 656 dbSNP
rs902130988 657 dbSNP
rs1367732175 660 dbSNP
rs1450167147 663 dbSNP
rs1165214036 665 dbSNP
rs1425017968 666 dbSNP
rs1384386015 667 dbSNP
rs1185256963 672 dbSNP
rs1190644864 673 dbSNP
rs1261815627 674 dbSNP
rs895967213 683 dbSNP
rs1487094050 691 dbSNP
rs997768993 708 dbSNP
rs1058867 720 dbSNP
rs1359082904 728 dbSNP
rs1290058890 734 dbSNP
rs951060741 739 dbSNP
rs1230241637 746 dbSNP
rs766438161 747 dbSNP
rs982831273 748 dbSNP
rs577554447 750 dbSNP
rs1465751906 751 dbSNP
rs1347501595 752 dbSNP
rs904806222 753 dbSNP
rs555463504 760 dbSNP
rs567397652 762 dbSNP
rs1017929175 763 dbSNP
rs1463436655 764 dbSNP
rs184380137 765 dbSNP
rs963748807 771 dbSNP
rs1169689052 772 dbSNP
rs1398794169 776 dbSNP
rs998309714 796 dbSNP
rs886057010 797 dbSNP
rs556351777 801 dbSNP
rs1199616610 805 dbSNP
rs1319803134 812 dbSNP
rs118117891 817 dbSNP
rs1265699585 819 dbSNP
rs777969090 830 dbSNP
rs991323324 842 dbSNP
rs1481232642 849 dbSNP
rs1300649528 851 dbSNP
rs1251196609 853 dbSNP
rs1217342228 859 dbSNP
rs1325688563 863 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084041. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep1 ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' uuccUCGUUCCGCCGUAGAGa 5'
              ||::|| |  |||||| 
Target 5' --aaAGUGAGACUCCAUCUCa 3'
1 - 19
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Cardiac Tissues
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM2202479. RNA binding protein: AGO2. Condition:S4_LV_29yo_Male_AGO2_bound_RNA ...

- Spengler RM; Zhang X; Cheng C; McLendon JM; et al., 2016, Nucleic acids research.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' uuccUCGUUCCGCCGUAGAGa 5'
              ||::|| |  |||||| 
Target 5' ---aAGUGAGACUCCAUCUCa 3'
1 - 18
Article - Spengler RM; Zhang X; Cheng C; McLendon JM; et al.
- Nucleic acids research, 2016
MicroRNAs (miRs) have emerged as key biological effectors in human health and disease. These small noncoding RNAs are incorporated into Argonaute (Ago) proteins, where they direct post-transcriptional gene silencing via base-pairing with target transcripts. Although miRs have become intriguing biological entities and attractive therapeutic targets, the translational impacts of miR research remain limited by a paucity of empirical miR targeting data, particularly in human primary tissues. Here, to improve our understanding of the diverse roles miRs play in cardiovascular function and disease, we applied high-throughput methods to globally profile miR:target interactions in human heart tissues. We deciphered Ago2:RNA interactions using crosslinking immunoprecipitation coupled with high-throughput sequencing (HITS-CLIP) to generate the first transcriptome-wide map of miR targeting events in human myocardium, detecting 4000 cardiac Ago2 binding sites across >2200 target transcripts. Our initial exploration of this interactome revealed an abundance of miR target sites in gene coding regions, including several sites pointing to new miR-29 functions in regulating cardiomyocyte calcium, growth and metabolism. Also, we uncovered several clinically-relevant interactions involving common genetic variants that alter miR targeting events in cardiomyopathy-associated genes. Overall, these data provide a critical resource for bolstering translational miR research in heart, and likely beyond.
LinkOut: [PMID: 27418678]
CLIP-seq Support 1 for dataset GSM1084041
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep1
Location of target site ENST00000290200.2 | 3UTR | AAAGUGAGACUCCAUCUCAAAAAAAAAAAAAAAAAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
94 hsa-miR-4708-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT095681 RBM27 RNA binding motif protein 27 2 4
MIRT104033 USP42 ubiquitin specific peptidase 42 2 6
MIRT114773 CMPK1 cytidine/uridine monophosphate kinase 1 2 2
MIRT246923 CCND1 cyclin D1 2 2
MIRT392569 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT443949 LRIT3 leucine rich repeat, Ig-like and transmembrane domains 3 2 2
MIRT446695 PAPPA pappalysin 1 2 2
MIRT447383 VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 2 2
MIRT449321 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT449717 C1orf61 chromosome 1 open reading frame 61 2 2
MIRT449738 TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 2 2
MIRT450531 PGLS 6-phosphogluconolactonase 2 2
MIRT455650 YARS tyrosyl-tRNA synthetase 2 2
MIRT458036 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT463468 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT466677 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 4
MIRT467789 SLC2A14 solute carrier family 2 member 14 2 2
MIRT468167 SGPL1 sphingosine-1-phosphate lyase 1 2 2
MIRT468652 SECISBP2L SECIS binding protein 2 like 2 6
MIRT469380 RER1 retention in endoplasmic reticulum sorting receptor 1 2 2
MIRT470346 PPP2R5E protein phosphatase 2 regulatory subunit B'epsilon 2 2
MIRT472418 NCKAP1 NCK associated protein 1 2 2
MIRT474612 KLF3 Kruppel like factor 3 2 2
MIRT478703 CSRNP2 cysteine and serine rich nuclear protein 2 2 2
MIRT481008 BBC3 BCL2 binding component 3 2 4
MIRT483098 TFPI tissue factor pathway inhibitor 2 2
MIRT485113 SHISA6 shisa family member 6 2 2
MIRT497533 ZNF607 zinc finger protein 607 2 2
MIRT500644 TUBB2A tubulin beta 2A class IIa 2 6
MIRT500890 STRN striatin 2 4
MIRT501900 MED13 mediator complex subunit 13 2 2
MIRT506646 MAPK1 mitogen-activated protein kinase 1 2 4
MIRT512675 ENO4 enolase family member 4 2 2
MIRT516977 OR7D2 olfactory receptor family 7 subfamily D member 2 2 2
MIRT528754 RPS27 ribosomal protein S27 2 6
MIRT539670 ZBTB44 zinc finger and BTB domain containing 44 2 2
MIRT544129 PPIL1 peptidylprolyl isomerase like 1 2 2
MIRT546382 STOX2 storkhead box 2 2 4
MIRT562143 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT568713 TMEM30B transmembrane protein 30B 2 2
MIRT571029 CENPP centromere protein P 2 2
MIRT572781 ZNF277 zinc finger protein 277 2 2
MIRT573162 SLC30A9 solute carrier family 30 member 9 2 2
MIRT609126 NUDT3 nudix hydrolase 3 2 2
MIRT609284 OAS3 2'-5'-oligoadenylate synthetase 3 2 2
MIRT613430 GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 2 2
MIRT613770 TTC38 tetratricopeptide repeat domain 38 2 2
MIRT616645 LRAT lecithin retinol acyltransferase 2 4
MIRT630892 SLC25A33 solute carrier family 25 member 33 2 2
MIRT636526 FAXC failed axon connections homolog 2 4
MIRT641394 NUBPL nucleotide binding protein like 2 2
MIRT641412 SCN2B sodium voltage-gated channel beta subunit 2 2 2
MIRT642528 CERS4 ceramide synthase 4 2 2
MIRT643186 HYPK huntingtin interacting protein K 2 2
MIRT647800 FRMD8 FERM domain containing 8 2 2
MIRT652150 TRIM71 tripartite motif containing 71 2 2
MIRT652602 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT661606 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT666339 SKAP2 src kinase associated phosphoprotein 2 2 2
MIRT670414 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT671122 ZNF573 zinc finger protein 573 2 2
MIRT671155 ANKRD9 ankyrin repeat domain 9 2 2
MIRT671338 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT671869 ZNF429 zinc finger protein 429 2 2
MIRT671974 IKZF3 IKAROS family zinc finger 3 2 2
MIRT672064 KIAA0930 KIAA0930 2 2
MIRT672654 SLC25A16 solute carrier family 25 member 16 2 4
MIRT672673 GTF2H5 general transcription factor IIH subunit 5 2 2
MIRT672771 UBE2V2 ubiquitin conjugating enzyme E2 V2 2 2
MIRT672929 LRRC2 leucine rich repeat containing 2 2 2
MIRT673159 C1orf50 chromosome 1 open reading frame 50 2 2
MIRT673272 RUNDC1 RUN domain containing 1 2 2
MIRT673332 THAP1 THAP domain containing 1 2 2
MIRT673351 SLC35F6 solute carrier family 35 member F6 2 2
MIRT673667 ZNF440 zinc finger protein 440 2 2
MIRT673904 DCTN6 dynactin subunit 6 2 2
MIRT674096 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT674401 MYCBP MYC binding protein 2 2
MIRT674525 PRR23A proline rich 23A 2 2
MIRT674793 NPR1 natriuretic peptide receptor 1 2 2
MIRT674833 ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 2 2
MIRT675066 FGD6 FYVE, RhoGEF and PH domain containing 6 2 2
MIRT675080 CCR6 C-C motif chemokine receptor 6 2 2
MIRT675126 FSD2 fibronectin type III and SPRY domain containing 2 2 2
MIRT679401 IL10RB interleukin 10 receptor subunit beta 2 2
MIRT689229 RPS19 ribosomal protein S19 2 2
MIRT694008 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT699671 SFT2D2 SFT2 domain containing 2 2 2
MIRT706213 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT706548 GJD2 gap junction protein delta 2 2 2
MIRT707418 RRP7A ribosomal RNA processing 7 homolog A 2 2
MIRT710648 GLUL glutamate-ammonia ligase 2 2
MIRT719393 NPCA1 Nasopharyngeal carcinoma 1 2 2
MIRT720166 PNPO pyridoxamine 5'-phosphate oxidase 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4708-5p Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4708-5p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4708-5p Tripterygium wilfordii Hook F sensitive tissue
hsa-miR-4708-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-4708-5p Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-4708-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)

Error report submission