miRTarBase - #MIRT687758


—
pre-miRNA Information
pre-miRNA hsa-mir-3622b   
Genomic Coordinates chr8: 27701673 - 27701767
Description Homo sapiens miR-3622b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3622b-3p
Sequence 58| UCACCUGAGCUCCCGUGCCUG |78
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1232922758 2 dbSNP
rs530939348 5 dbSNP
rs1439657384 10 dbSNP
rs1157333896 12 dbSNP
rs66683138 14 dbSNP
rs1044808718 15 dbSNP
rs946438979 19 dbSNP
rs551845360 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol KIAA1328   
Synonyms -
Description KIAA1328
Transcript NM_020776   
Expression
Putative miRNA Targets on KIAA1328
3'UTR of KIAA1328
(miRNA target sites are highlighted)		 
>KIAA1328|NM_020776|3'UTR
   1 CATATTGCAAAATTTTCTTAGGAAATTTGTGGGTTTCCTCACATACTGATCTAGGATTTTAAATTATTTCATTGCAAAGT
  81 AATTGTGTCTCTCCTTTCACGGGGACTTGTCTCACTAGCATCCTGTTACGTATTGAATATAGAAATCATTCTAACAACCC
 161 AGGTTATTTTCAATCAGACCAGGCATTCGATAACACACTAAGGGGGTAGGAATGGAAGATGGTATCTTTTATATGCTAAA
 241 CAGATTAGAAAATTAACATAGGATACTTTCTGCGTGGTGGAAACCATTGCATATTCAGCCTCATTTCAAGAGTGTTTCCT
 321 TCTCAAACTTCTGCTAGAAAATGCTGACTCACTTTTATATACAAGAAAAACCTTTCCACTGAAAAATCCCTCTGATTTAA
 401 AAGTAACCCCTTTGAAACATAAGCAGTTTCAGAAAGGCAGACTCTCTCATCTTTCTCATCCTGTTCTCTCACTACTACAT
 481 TTCTGTAAGTGGTCCTTTAATTCTGAAGTTGGAGTTGGTGCCCCTGCCATCACAAACAACACGAGAGCCAATTGTGAGTC
 561 AGTCTCAGTAGCCATCAGCCTGGCAGCTGCCCATCCCATAACCAAAGAGCTCAATGGGCTGGAGGGTGAGACCCAGCCAA
 641 TCCTTGGGAGCAAGCAGCACTAAATCACATCAGGGAGTGATTAGTCCTGGGGAAATTCAGTGGAGGCACAAGCCTGAAGC
 721 ACTCTTCTACCAATGTTTGGGTGACCACCCCTCCAATATCCCAGAATGAATAAGAACAATCCCTAGGTATTTTTATTTAC
 801 CCAAGTGTTCAGCTTATTCACCCCACCCCCCCACCCCCCATCACACGTGCTCCTGTGAACTTTCCATGGTTATGTCTACG
 881 GAAAATGCCACTAGAGAGAGAGTGATGCAAGCTGCTGCAAAGCTGATGGGCTTCCTCTGGCCCTCCCTTTTCCTCCACGA
 961 GGATTAAAGGATACAAGCTGACCAGGCCTCACAGGTGCTCTGCTCGTGGCCCCAAAGAACCATCTCTACTTGCCAGAGTA
1041 TGTTCCACCACCCAAGCAGGGTCTCCCTACTTTTTCTCACTGGCCTCGTTTTGACCCAGAGAAAGCCTATGGAAGTTATG
1121 CAGTGCAGACCTCATCCTGTCTGCTGTCTTTTCTCCCACAGAGCTCTTGAGATGGGTCCTTCAGCTTGCAGTGGTCCCTA
1201 GTAGCCTCTCAAGCTAATGGGGATGATGATCCTGGTTTAGCCAGAGTTCAAAACTCTCCAGTCATTGAAAGCAAGGGGAG
1281 GGTGTGTTCCCAGATGTGTATTACTTGGGAATTTTATTTGATCTGGAGGGTGTGGCTTTTTTTCTCTCCTTTTTACCAAC
1361 CCCAACTAAACTGGGAGTAAGACTTAGTCAGTGTTGGTAGACAAAGTCATACCACCCAGGGCAGCCTGCATGCAGCGAGT
1441 CTGCGTGGCTTCCCTGAATTACTCTTTTAATTAAAACTAGATTATTTCAATCTAGAAAAGCCTTGTTGAGCAGCCTCCTT
1521 ATCCAGATAGATCCAAAGCTCATGTCTCTTCAGGCTGAGACTGGCGCTGTCACCTCCACCCAGCCTTCTTTCACTTGGGG
1601 TTTTTTATTCTTTGGAGTAGAAAAGAATGGAGCCCACTAATATTATATTTTTCTTCTGAAATAAATATAAAGTCAAGACT
1681 AACTAGTTATAATCATTCCCTTAAAAAGTTGGAAAATCATTACAGATTAAAATTTCTTTATAAAGTTCACCTCTGAGAGT
1761 AACCAAATCGGTTTCATCCCATATCAAAAAGCCTTTGGAGTGTGGAGCTTTCTGTGGTATGGCAGAAATGGGTGGATGGC
1841 AAACTAAGAGCCCTCAGCCATTTTTTCAGTTAAAGTTAGGTTGCCAGAACTTTCTTTTCCTTGCCCCCTGTGTCATGACT
1921 AGCTTAAGTGTACTTGACTCCCATAGACTACTCCCATGCCCACAGTCACCCATTCCAGACTCCAGTGTCCTTAAAACTCT
2001 GGAGTGAGAGGATGCCAGAGGATCAAGAAAAGGATCACAGTTTCTTGAAGAAGCTTGTTTGCCTTTAGAAGAATCGTAAA
2081 CAGAGTCTAAACTAAAGGCTTTTTGGGGGTCACAGCCACAGAGTGGAGTTTTATTGCTTCTTTGCCTCTCCATGAATGGC
2161 CAATTTGGAAAAGCAGAGATGGGCTTTCAGCAGAATATCAACCAATACATTTTTCACATGCAAAACTCATCACCAGTTGC
2241 CTTTTTCTAACTTAATGGACATTTTGTTGGTGTTGGTGCAAGGGCAATAGGATGTAAATTTGTATATAATCTAATGTCTT
2321 CATTATTAATTGAATAGTACATGTTAACATTTTAATCTATTTAAATTTACTTTGAAATATATACATACATATGAATGAAA
2401 GGTTGTTACAGAGCCTCAAAGCTGTTGCAGACTATCCCAAGAGAAAGGATCTGGCACAAAGGAATCTGCCTTTCCTCCGT
2481 CTCAAGTCTCCCACCCTTGACTGGTTGGGATTTGCTCGTCCAGCCTCTAGACACTTCCCAAAGCAAGACTGGACACATGC
2561 CGAGGGCGTTGCGGATAGTGCCTCACCATTGCCCACCCTGCTGCCCAACTCCTGTGAGAGAAAAACCAATCAATGTTTAC
2641 AAAATGGAAAAGGACACAGCATGTCCTTTGAACTCCCTAAGTAAGGCCCACAGTTCTTGATGCAGAGAACCAAAGTGAAT
2721 CATAGAAAAGCTTTTGCTAACAGTCCGCTTTCCAGGAGGCAAACTTGTGTTTATCCAAACCTGATCCCCATGATGGGGAC
2801 TTTTCTAGAGCACCCCAAATGTCATGGGGAGAGAGGGACTCTTTCTGCTCCCTCAGAGCTACTCTTCACTTGTCCCTGCT
2881 TCCGGCACCAAGTTCATAATAGAGATCTTCTGGCCAGAGAATCAGGGGAGAGGAGAGGCCTGATGGGGCAGAGCTGGACG
2961 AAGTCTGCTAAGAGAGATGGAGGCTGTGGCGGACTCCTTCCAACTCACGATTTATCCTCAGCTCAGAGTGTATTTTGAAT
3041 ATGAGCAAATGTTTATGTACGTATGAGATTTCAAGTTAATAAATCATCTCTATGGCTAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guccgugcccUCGAGUC-CACu 5'
                    ||||||| ||| 
Target 5' atttatcctcAGCTCAGAGTGt 3'
 3010 - 3031 123.00 -13.40
2 
miRNA  3' guccgugcccucgaGUCCACu 5'
                        |||||| 
Target 5' ctgaccaggcctcaCAGGTGc 3'
 978 - 998 120.00 -13.40
3 
miRNA  3' guCCGUGCCCUCGAGUCCACu 5'
            |||  | ||  ||||| | 
Target 5' ctGGCCAGAGA-ATCAGGGGa 3'
 2910 - 2929 118.00 -13.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31548495 90 COSMIC
COSN30122317 98 COSMIC
COSN30125470 102 COSMIC
COSN31585178 189 COSMIC
COSN1205429 198 COSMIC
COSN27129321 603 COSMIC
COSN7357120 769 COSMIC
COSN6416262 859 COSMIC
COSN6664366 881 COSMIC
COSN15230811 1130 COSMIC
COSN8678331 1130 COSMIC
COSN18976951 1657 COSMIC
COSN8250398 1660 COSMIC
COSN17181580 1931 COSMIC
COSN25719772 2149 COSMIC
COSN27025657 2214 COSMIC
COSN17075861 2561 COSMIC
COSN15668377 2745 COSMIC
COSN20114927 2925 COSMIC
rs2017027 3005 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1465958017 5 dbSNP
rs774479072 6 dbSNP
rs758776943 9 dbSNP
rs926177586 9 dbSNP
rs747028179 11 dbSNP
rs367550105 15 dbSNP
rs1053777921 17 dbSNP
rs1158233278 21 dbSNP
rs1345981314 27 dbSNP
rs1415661448 30 dbSNP
rs1053707024 33 dbSNP
rs1291845997 34 dbSNP
rs1388579594 41 dbSNP
rs894003640 62 dbSNP
rs1158567699 63 dbSNP
rs1438308056 71 dbSNP
rs1417486623 75 dbSNP
rs1179593704 79 dbSNP
rs891931724 86 dbSNP
rs1012406900 101 dbSNP
rs1212578192 104 dbSNP
rs116461638 105 dbSNP
rs1401519940 115 dbSNP
rs1283738634 122 dbSNP
rs906747327 127 dbSNP
rs544162044 130 dbSNP
rs78344684 131 dbSNP
rs573579866 143 dbSNP
rs1027299515 150 dbSNP
rs887704078 154 dbSNP
rs1300700018 156 dbSNP
rs1449861006 159 dbSNP
rs1359384596 171 dbSNP
rs1157466411 174 dbSNP
rs1417343411 176 dbSNP
rs972500339 180 dbSNP
rs1004769339 184 dbSNP
rs542567995 187 dbSNP
rs141051093 189 dbSNP
rs1353224017 190 dbSNP
rs1006824190 194 dbSNP
rs1412154746 198 dbSNP
rs952688274 199 dbSNP
rs960525732 204 dbSNP
rs1483664042 205 dbSNP
rs187536164 211 dbSNP
rs1662906 219 dbSNP
rs1240856817 222 dbSNP
rs1320885303 224 dbSNP
rs1317088562 225 dbSNP
rs970053216 227 dbSNP
rs1229830488 239 dbSNP
rs980525798 245 dbSNP
rs537180820 257 dbSNP
rs976624637 263 dbSNP
rs1280734762 265 dbSNP
rs757695401 274 dbSNP
rs559330237 275 dbSNP
rs1361961414 277 dbSNP
rs1210970921 303 dbSNP
rs1256856561 328 dbSNP
rs192808978 340 dbSNP
rs1196144959 342 dbSNP
rs115993757 353 dbSNP
rs1191828449 358 dbSNP
rs1449988824 362 dbSNP
rs1478835517 363 dbSNP
rs1264075917 365 dbSNP
rs1209322582 367 dbSNP
rs1040172778 372 dbSNP
rs1263631578 373 dbSNP
rs1223440077 377 dbSNP
rs1475292095 379 dbSNP
rs1166509582 382 dbSNP
rs529282514 390 dbSNP
rs1787627 395 dbSNP
rs1341834714 397 dbSNP
rs1278206677 400 dbSNP
rs1385748028 401 dbSNP
rs1389144239 404 dbSNP
rs1458707797 408 dbSNP
rs1400098125 419 dbSNP
rs1049211444 442 dbSNP
rs1312764819 447 dbSNP
rs184970117 452 dbSNP
rs1401243575 461 dbSNP
rs1431538301 463 dbSNP
rs1298437397 469 dbSNP
rs1005246783 475 dbSNP
rs1468742135 484 dbSNP
rs1257264587 493 dbSNP
rs906794387 499 dbSNP
rs1276374024 500 dbSNP
rs1003828422 503 dbSNP
rs1345679850 507 dbSNP
rs1218607418 509 dbSNP
rs1278038200 514 dbSNP
rs1013352519 515 dbSNP
rs1015167332 517 dbSNP
rs1304024897 524 dbSNP
rs1023398745 525 dbSNP
rs896864782 526 dbSNP
rs1329657922 528 dbSNP
rs993827368 532 dbSNP
rs115385528 534 dbSNP
rs952471343 538 dbSNP
rs1218798748 541 dbSNP
rs985710177 543 dbSNP
rs150128999 544 dbSNP
rs1033468151 552 dbSNP
rs1454610367 559 dbSNP
rs965565368 562 dbSNP
rs976673822 574 dbSNP
rs1176493002 576 dbSNP
rs1458949880 579 dbSNP
rs923851176 583 dbSNP
rs1250755938 585 dbSNP
rs1199571680 599 dbSNP
rs571897979 603 dbSNP
rs956711907 605 dbSNP
rs1342254792 610 dbSNP
rs989497672 615 dbSNP
rs1248852523 622 dbSNP
rs913467761 626 dbSNP
rs1307749607 627 dbSNP
rs1449416324 629 dbSNP
rs1336772283 637 dbSNP
rs1333734984 652 dbSNP
rs1394579340 659 dbSNP
rs1478533553 673 dbSNP
rs1303448324 678 dbSNP
rs1173577350 707 dbSNP
rs201616043 710 dbSNP
rs966261748 711 dbSNP
rs915331092 712 dbSNP
rs948136007 716 dbSNP
rs1045545443 723 dbSNP
rs1441294497 724 dbSNP
rs537614792 730 dbSNP
rs939498238 733 dbSNP
rs557386518 734 dbSNP
rs1257862284 741 dbSNP
rs1331490481 742 dbSNP
rs931725096 747 dbSNP
rs1439811938 752 dbSNP
rs1284472106 755 dbSNP
rs898046667 756 dbSNP
rs1351841029 759 dbSNP
rs1379018915 760 dbSNP
rs1048801516 761 dbSNP
rs1243089575 769 dbSNP
rs993851969 773 dbSNP
rs1399445920 783 dbSNP
rs138217393 788 dbSNP
rs1296257302 798 dbSNP
rs1402305094 799 dbSNP
rs1048028769 801 dbSNP
rs1162381593 803 dbSNP
rs1471706267 804 dbSNP
rs1242476494 808 dbSNP
rs1188271434 811 dbSNP
rs1036258413 813 dbSNP
rs888097009 814 dbSNP
rs1218173162 826 dbSNP
rs71381582 826 dbSNP
rs896424072 826 dbSNP
rs999805645 826 dbSNP
rs1261360372 827 dbSNP
rs1208396076 828 dbSNP
rs1013425610 829 dbSNP
rs1218316395 831 dbSNP
rs1338515818 832 dbSNP
rs1280108128 833 dbSNP
rs1030785439 834 dbSNP
rs1382930175 837 dbSNP
rs1326911534 838 dbSNP
rs1203635901 840 dbSNP
rs1180666915 841 dbSNP
rs1452555036 842 dbSNP
rs1193403065 844 dbSNP
rs1251746480 846 dbSNP
rs1403363242 847 dbSNP
rs1396481614 848 dbSNP
rs375739832 858 dbSNP
rs1165187369 865 dbSNP
rs1006664038 867 dbSNP
rs1044880923 869 dbSNP
rs867178420 880 dbSNP
rs1786059 881 dbSNP
rs1362739267 893 dbSNP
rs1475476054 893 dbSNP
rs1468110987 900 dbSNP
rs1246609738 919 dbSNP
rs1197434450 926 dbSNP
rs997939561 927 dbSNP
rs1030877554 928 dbSNP
rs1274273041 931 dbSNP
rs1164647060 932 dbSNP
rs1390917882 939 dbSNP
rs1316241586 945 dbSNP
rs1002061897 953 dbSNP
rs1215206902 954 dbSNP
rs1344456790 956 dbSNP
rs542947277 959 dbSNP
rs989454209 960 dbSNP
rs536153708 974 dbSNP
rs3747899 976 dbSNP
rs969778290 978 dbSNP
rs149158097 983 dbSNP
rs1020269021 987 dbSNP
rs980919433 994 dbSNP
rs966292373 999 dbSNP
rs976291950 1005 dbSNP
rs928030978 1007 dbSNP
rs939509731 1010 dbSNP
rs1171333902 1013 dbSNP
rs1455915049 1024 dbSNP
rs1306141934 1025 dbSNP
rs1254200384 1031 dbSNP
rs1335261825 1036 dbSNP
rs780201538 1041 dbSNP
rs546433487 1050 dbSNP
rs747246045 1052 dbSNP
rs1286242458 1068 dbSNP
rs984976233 1070 dbSNP
rs8085064 1074 dbSNP
rs143247580 1088 dbSNP
rs1276505810 1089 dbSNP
rs1221026960 1090 dbSNP
rs1213517021 1097 dbSNP
rs544352077 1110 dbSNP
rs1304111953 1124 dbSNP
rs1459340487 1138 dbSNP
rs1239126071 1147 dbSNP
rs1374452355 1153 dbSNP
rs1299513804 1164 dbSNP
rs1442574464 1165 dbSNP
rs1358224362 1172 dbSNP
rs1331568022 1178 dbSNP
rs930910647 1182 dbSNP
rs1199845147 1183 dbSNP
rs1396176378 1192 dbSNP
rs971715834 1194 dbSNP
rs1049759521 1201 dbSNP
rs561030592 1202 dbSNP
rs1178140793 1211 dbSNP
rs949345705 1226 dbSNP
rs1416791455 1240 dbSNP
rs1235969426 1252 dbSNP
rs888155972 1256 dbSNP
rs905056473 1259 dbSNP
rs189428409 1261 dbSNP
rs1368741305 1277 dbSNP
rs768375799 1278 dbSNP
rs1474662751 1287 dbSNP
rs1162574276 1288 dbSNP
rs1351229634 1291 dbSNP
rs546571171 1292 dbSNP
rs1224144276 1298 dbSNP
rs936499397 1325 dbSNP
rs900890078 1327 dbSNP
rs181026750 1336 dbSNP
rs1297543411 1344 dbSNP
rs1394243264 1355 dbSNP
rs1298115565 1374 dbSNP
rs1010292241 1375 dbSNP
rs1347473877 1386 dbSNP
rs1020298535 1388 dbSNP
rs776286878 1390 dbSNP
rs1411862959 1392 dbSNP
rs901840657 1395 dbSNP
rs1030764499 1397 dbSNP
rs1262659255 1406 dbSNP
rs997801441 1407 dbSNP
rs1007642855 1408 dbSNP
rs28676465 1410 dbSNP
rs1287282367 1416 dbSNP
rs1234823348 1419 dbSNP
rs984992999 1423 dbSNP
rs1397614285 1432 dbSNP
rs1010850113 1437 dbSNP
rs528473045 1438 dbSNP
rs969449589 1441 dbSNP
rs981146963 1446 dbSNP
rs551927406 1448 dbSNP
rs1167371202 1462 dbSNP
rs917618415 1465 dbSNP
rs1035114461 1476 dbSNP
rs139074124 1496 dbSNP
rs537258242 1498 dbSNP
rs919449181 1502 dbSNP
rs1263733043 1509 dbSNP
rs1187092502 1515 dbSNP
rs1488030215 1523 dbSNP
rs1250832513 1528 dbSNP
rs557578591 1531 dbSNP
rs1257565887 1545 dbSNP
rs1335020774 1558 dbSNP
rs1257064864 1562 dbSNP
rs926579090 1566 dbSNP
rs930796455 1567 dbSNP
rs1296904320 1568 dbSNP
rs1386773915 1573 dbSNP
rs1366123302 1574 dbSNP
rs936557090 1578 dbSNP
rs1185366782 1584 dbSNP
rs1053636617 1589 dbSNP
rs28639668 1592 dbSNP
rs1478064405 1601 dbSNP
rs910758470 1607 dbSNP
rs1373781725 1611 dbSNP
rs942382064 1621 dbSNP
rs536986899 1626 dbSNP
rs1175458028 1627 dbSNP
rs1432466813 1633 dbSNP
rs1393217550 1634 dbSNP
rs1371319375 1637 dbSNP
rs1467497403 1646 dbSNP
rs1468782681 1656 dbSNP
rs1173052760 1659 dbSNP
rs1237167481 1669 dbSNP
rs946152328 1669 dbSNP
rs1041815354 1678 dbSNP
rs1251319702 1685 dbSNP
rs901873257 1691 dbSNP
rs1346285205 1712 dbSNP
rs1306313274 1720 dbSNP
rs1414183437 1722 dbSNP
rs1376698861 1735 dbSNP
rs1039751773 1739 dbSNP
rs900945583 1743 dbSNP
rs1397500247 1745 dbSNP
rs1029383764 1752 dbSNP
rs933773230 1754 dbSNP
rs184233403 1759 dbSNP
rs572525311 1761 dbSNP
rs1295276439 1770 dbSNP
rs1016434120 1771 dbSNP
rs1236107553 1774 dbSNP
rs1281600308 1777 dbSNP
rs1379529884 1786 dbSNP
rs1346528175 1793 dbSNP
rs962179745 1810 dbSNP
rs1208096983 1813 dbSNP
rs1420448164 1814 dbSNP
rs1250830177 1818 dbSNP
rs971818696 1821 dbSNP
rs1024663804 1835 dbSNP
rs1185759596 1856 dbSNP
rs544567715 1869 dbSNP
rs1278087784 1884 dbSNP
rs1241652564 1886 dbSNP
rs1336535813 1890 dbSNP
rs1259440277 1891 dbSNP
rs1434640313 1894 dbSNP
rs753650608 1895 dbSNP
rs980418332 1895 dbSNP
rs1011148030 1899 dbSNP
rs1434253847 1904 dbSNP
rs1171828240 1905 dbSNP
rs1377416322 1906 dbSNP
rs957984455 1908 dbSNP
rs1435187776 1911 dbSNP
rs989800831 1917 dbSNP
rs1455184745 1933 dbSNP
rs1022220081 1945 dbSNP
rs1454473430 1971 dbSNP
rs1473935450 1981 dbSNP
rs1258918965 1984 dbSNP
rs773231137 1986 dbSNP
rs945178519 2004 dbSNP
rs1288467372 2005 dbSNP
rs1360338172 2007 dbSNP
rs1207228951 2011 dbSNP
rs1388823449 2049 dbSNP
rs1304896539 2050 dbSNP
rs1351909671 2051 dbSNP
rs1265072753 2074 dbSNP
rs1231762980 2076 dbSNP
rs905071199 2077 dbSNP
rs1370892116 2080 dbSNP
rs1041847130 2094 dbSNP
rs1325748406 2100 dbSNP
rs1002222871 2105 dbSNP
rs933360596 2109 dbSNP
rs376616703 2111 dbSNP
rs1316949116 2112 dbSNP
rs1163947716 2113 dbSNP
rs1214662909 2116 dbSNP
rs1035047619 2119 dbSNP
rs1459491195 2139 dbSNP
rs558238275 2140 dbSNP
rs889074664 2145 dbSNP
rs972181618 2147 dbSNP
rs1026391332 2154 dbSNP
rs762316709 2157 dbSNP
rs1321722111 2158 dbSNP
rs985323799 2160 dbSNP
rs910821533 2164 dbSNP
rs1214086994 2165 dbSNP
rs1252358266 2168 dbSNP
rs1038346870 2175 dbSNP
rs1212224885 2183 dbSNP
rs943590816 2184 dbSNP
rs976350256 2207 dbSNP
rs1218061716 2216 dbSNP
rs1337592591 2220 dbSNP
rs1452475272 2225 dbSNP
rs1191872053 2227 dbSNP
rs1326964022 2239 dbSNP
rs1324913901 2240 dbSNP
rs142978608 2245 dbSNP
rs933658579 2270 dbSNP
rs1396181835 2277 dbSNP
rs1419698268 2284 dbSNP
rs564492933 2285 dbSNP
rs754866118 2288 dbSNP
rs543972001 2289 dbSNP
rs1052170125 2305 dbSNP
rs892181738 2307 dbSNP
rs946573851 2311 dbSNP
rs957933050 2315 dbSNP
rs1326971166 2316 dbSNP
rs989440212 2328 dbSNP
rs765996717 2330 dbSNP
rs1394450752 2340 dbSNP
rs1470144378 2342 dbSNP
rs1043927666 2349 dbSNP
rs1198319466 2357 dbSNP
rs905011291 2359 dbSNP
rs1002554244 2360 dbSNP
rs375600629 2370 dbSNP
rs1312040090 2379 dbSNP
rs913802794 2382 dbSNP
rs1215259285 2383 dbSNP
rs1034932383 2384 dbSNP
rs1302631409 2389 dbSNP
rs774078161 2392 dbSNP
rs1231773586 2402 dbSNP
rs1372984784 2402 dbSNP
rs993460411 2403 dbSNP
rs1026402132 2408 dbSNP
rs952202629 2422 dbSNP
rs966593193 2429 dbSNP
rs1373448916 2431 dbSNP
rs528434015 2438 dbSNP
rs1222636893 2449 dbSNP
rs1172371416 2459 dbSNP
rs1304501185 2466 dbSNP
rs976592755 2470 dbSNP
rs1395996660 2479 dbSNP
rs1018219572 2480 dbSNP
rs1468749206 2492 dbSNP
rs933393310 2498 dbSNP
rs964890485 2501 dbSNP
rs759254228 2509 dbSNP
rs1441964943 2511 dbSNP
rs561180505 2516 dbSNP
rs189513348 2519 dbSNP
rs1208724350 2535 dbSNP
rs1303802004 2537 dbSNP
rs955049154 2540 dbSNP
rs987728190 2545 dbSNP
rs368642081 2546 dbSNP
rs913670177 2562 dbSNP
rs942009951 2563 dbSNP
rs1037686910 2566 dbSNP
rs181847955 2567 dbSNP
rs946430743 2568 dbSNP
rs1311591277 2569 dbSNP
rs1043464486 2573 dbSNP
rs754131999 2574 dbSNP
rs1046552874 2576 dbSNP
rs926488074 2577 dbSNP
rs906708612 2581 dbSNP
rs937851429 2586 dbSNP
rs1001992482 2592 dbSNP
rs1255410982 2605 dbSNP
rs75466949 2610 dbSNP
rs957750670 2619 dbSNP
rs1011006771 2632 dbSNP
rs1406122418 2636 dbSNP
rs896362376 2649 dbSNP
rs1020601135 2658 dbSNP
rs528512856 2662 dbSNP
rs976623910 2666 dbSNP
rs186099323 2674 dbSNP
rs1333718568 2679 dbSNP
rs887773358 2689 dbSNP
rs1006742841 2700 dbSNP
rs1416118840 2702 dbSNP
rs565274879 2706 dbSNP
rs954001937 2707 dbSNP
rs1288845365 2713 dbSNP
rs1429045553 2715 dbSNP
rs1460150699 2718 dbSNP
rs1347382898 2722 dbSNP
rs750962719 2723 dbSNP
rs1160293846 2726 dbSNP
rs758414740 2747 dbSNP
rs780114103 2748 dbSNP
rs1167144894 2750 dbSNP
rs751706875 2751 dbSNP
rs965283427 2754 dbSNP
rs1475600756 2765 dbSNP
rs997606313 2766 dbSNP
rs866963327 2768 dbSNP
rs1185920749 2776 dbSNP
rs561721923 2782 dbSNP
rs1243568174 2789 dbSNP
rs1295921929 2795 dbSNP
rs1209141833 2798 dbSNP
rs1380941281 2803 dbSNP
rs942100212 2811 dbSNP
rs987780590 2818 dbSNP
rs913581214 2821 dbSNP
rs1234565275 2822 dbSNP
rs35394101 2826 dbSNP
rs967736218 2828 dbSNP
rs1295493927 2836 dbSNP
rs1213255922 2837 dbSNP
rs1364715260 2845 dbSNP
rs1289768674 2849 dbSNP
rs979625311 2853 dbSNP
rs1392516971 2868 dbSNP
rs1328235137 2872 dbSNP
rs1233556487 2876 dbSNP
rs1292236713 2877 dbSNP
rs919220996 2884 dbSNP
rs926358503 2885 dbSNP
rs747784382 2893 dbSNP
rs531074342 2894 dbSNP
rs906738398 2899 dbSNP
rs755168732 2906 dbSNP
rs917851628 2920 dbSNP
rs1215247362 2922 dbSNP
rs938158865 2923 dbSNP
rs1055275209 2924 dbSNP
rs1309739188 2924 dbSNP
rs35952844 2924 dbSNP
rs929235438 2926 dbSNP
rs1233995683 2939 dbSNP
rs371909974 2939 dbSNP
rs1369319773 2942 dbSNP
rs550781166 2944 dbSNP
rs190522560 2949 dbSNP
rs1396063533 2958 dbSNP
rs1486668870 2960 dbSNP
rs181622782 2961 dbSNP
rs1256999595 2964 dbSNP
rs1356180875 2967 dbSNP
rs1169203579 2978 dbSNP
rs546902732 2989 dbSNP
rs1474467881 2991 dbSNP
rs781514481 2992 dbSNP
rs1006216485 2993 dbSNP
rs1039539699 3001 dbSNP
rs2017027 3005 dbSNP
rs997659878 3008 dbSNP
rs1481357515 3009 dbSNP
rs1420904105 3010 dbSNP
rs1409861411 3013 dbSNP
rs1029568117 3020 dbSNP
rs1346353576 3026 dbSNP
rs1168902958 3027 dbSNP
rs1234454294 3028 dbSNP
rs538248946 3044 dbSNP
rs1030430444 3051 dbSNP
rs891952270 3052 dbSNP
rs1305188598 3054 dbSNP
rs769652434 3060 dbSNP
rs796551269 3061 dbSNP
rs777509742 3062 dbSNP
rs1433961435 3078 dbSNP
rs1373581476 3079 dbSNP
rs749238786 3086 dbSNP
rs1016736683 3096 dbSNP
rs1311899333 3098 dbSNP
rs558179011 3108 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048188. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_ptb_knockdown ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' guccGUGCCCUCGAGUCCACu 5'
              | |  || |||||||| 
Target 5' --aaCUCCUGACCUCAGGUGa 3'
 		1 - 19
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM1048188
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_ptb_knockdown
Location of target site ENST00000592521.1 | 3UTR | AACUCCUGACCUCAGGUGAUCUGCCUGCCUUGGCCUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
THCA 0.235 0.31 -0.214 0.32 7 Click to see details
THCA 0.235 0.31 -0.214 0.32 7 Click to see details
THCA 0.235 0.31 -0.214 0.32 7 Click to see details
THCA 0.235 0.31 -0.214 0.32 7 Click to see details
THCA 0.235 0.31 -0.214 0.32 7 Click to see details
THCA 0.235 0.31 -0.214 0.32 7 Click to see details
102 hsa-miR-3622b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT076713 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT080212 PRKACB protein kinase cAMP-activated catalytic subunit beta 2 2
MIRT081398 GTPBP3 GTP binding protein 3, mitochondrial 2 2
MIRT107158 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT254071 BACH1 BTB domain and CNC homolog 1 2 2
MIRT409790 FOXO3 forkhead box O3 2 2
MIRT448679 MAPK9 mitogen-activated protein kinase 9 2 2
MIRT450206 ABHD15 abhydrolase domain containing 15 2 2
MIRT486621 PDK3 pyruvate dehydrogenase kinase 3 2 2
MIRT489267 TTLL1 tubulin tyrosine ligase like 1 2 2
MIRT493117 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 4
MIRT494570 BAK1 BCL2 antagonist/killer 1 2 2
MIRT497395 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT504900 CCDC86 coiled-coil domain containing 86 2 2
MIRT505192 USP46 ubiquitin specific peptidase 46 2 4
MIRT506522 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 6
MIRT508162 ABCC5 ATP binding cassette subfamily C member 5 2 8
MIRT508545 PARVG parvin gamma 2 4
MIRT509850 BIRC5 baculoviral IAP repeat containing 5 2 6
MIRT510088 PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2 8
MIRT512094 CRK CRK proto-oncogene, adaptor protein 2 4
MIRT515381 RPL7 ribosomal protein L7 2 2
MIRT519176 SCO1 SCO1, cytochrome c oxidase assembly protein 2 2
MIRT519964 ZCCHC8 zinc finger CCHC-type containing 8 2 2
MIRT522292 NKAP NFKB activating protein 2 2
MIRT523160 HMGB2 high mobility group box 2 2 4
MIRT525314 FANCA Fanconi anemia complementation group A 2 2
MIRT528194 PLEKHM2 pleckstrin homology and RUN domain containing M2 2 2
MIRT532885 ZNF451 zinc finger protein 451 2 2
MIRT538209 CYR61 cysteine rich angiogenic inducer 61 2 2
MIRT539497 ACTN4 actinin alpha 4 2 2
MIRT554600 RRAGC Ras related GTP binding C 2 2
MIRT562444 DCTN6 dynactin subunit 6 2 2
MIRT562748 AOC3 amine oxidase, copper containing 3 2 2
MIRT565798 SEC14L5 SEC14 like lipid binding 5 2 2
MIRT565838 SCML2 Scm polycomb group protein like 2 2 2
MIRT566072 RCC2 regulator of chromosome condensation 2 2 2
MIRT566104 RBPJ recombination signal binding protein for immunoglobulin kappa J region 2 2
MIRT572407 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT576198 Vsig2 V-set and immunoglobulin domain containing 2 2 2
MIRT576313 Acbd7 acyl-Coenzyme A binding domain containing 7 2 2
MIRT576651 Mill2 MHC I like leukocyte 2 1 1
MIRT576859 Socs6 suppressor of cytokine signaling 6 2 2
MIRT606819 BICD2 BICD cargo adaptor 2 2 2
MIRT610738 NUDT16 nudix hydrolase 16 2 4
MIRT614798 RORA RAR related orphan receptor A 2 2
MIRT619006 NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 2 2
MIRT619420 NOS1AP nitric oxide synthase 1 adaptor protein 2 2
MIRT620405 MYO1H myosin IH 2 2
MIRT624869 ABHD13 abhydrolase domain containing 13 2 2
MIRT633527 ZFP30 ZFP30 zinc finger protein 2 2
MIRT633927 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT636611 CLIC5 chloride intracellular channel 5 2 2
MIRT640616 MIOX myo-inositol oxygenase 2 2
MIRT642605 C14orf180 chromosome 14 open reading frame 180 2 2
MIRT644624 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT655113 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT658976 DNAJB5 DnaJ heat shock protein family (Hsp40) member B5 2 4
MIRT661495 CHMP1B charged multivesicular body protein 1B 2 2
MIRT662996 TMEM59 transmembrane protein 59 2 2
MIRT663075 SFR1 SWI5 dependent homologous recombination repair protein 1 2 2
MIRT665405 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT666106 SSR1 signal sequence receptor subunit 1 2 2
MIRT669562 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT670070 ZNF783 zinc finger family member 783 2 2
MIRT671192 ZNF891 zinc finger protein 891 2 2
MIRT675361 KLHL26 kelch like family member 26 2 2
MIRT678857 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT679443 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT684163 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT684543 ZNF460 zinc finger protein 460 2 2
MIRT684674 SLC2A11 solute carrier family 2 member 11 2 2
MIRT684971 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT686006 NEK4 NIMA related kinase 4 2 2
MIRT687758 KIAA1328 KIAA1328 2 2
MIRT688961 ATXN3 ataxin 3 2 2
MIRT689409 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT690001 MMP17 matrix metallopeptidase 17 2 2
MIRT690165 ELP3 elongator acetyltransferase complex subunit 3 2 2
MIRT690202 C5orf45 MRN complex interacting protein 2 2
MIRT690477 ZNF33A zinc finger protein 33A 2 2
MIRT690566 MICA MHC class I polypeptide-related sequence A 2 2
MIRT692160 C10orf111 chromosome 10 open reading frame 111 2 2
MIRT693430 PLGLB2 plasminogen-like B2 2 2
MIRT693547 ZNF708 zinc finger protein 708 2 2
MIRT693697 PLGLB1 plasminogen-like B1 2 2
MIRT695006 HSPA6 heat shock protein family A (Hsp70) member 6 2 2
MIRT698525 TFRC transferrin receptor 2 2
MIRT699574 SIKE1 suppressor of IKBKE 1 2 2
MIRT703446 FYTTD1 forty-two-three domain containing 1 2 2
MIRT704397 CTSS cathepsin S 2 2
MIRT704485 CPT1A carnitine palmitoyltransferase 1A 2 2
MIRT709822 STPG1 sperm tail PG-rich repeat containing 1 2 2
MIRT710859 COQ7 coenzyme Q7, hydroxylase 2 2
MIRT711893 INSIG2 insulin induced gene 2 2 2
MIRT713796 CPLX2 complexin 2 2 2
MIRT718800 C1GALT1C1 C1GALT1 specific chaperone 1 2 2
MIRT719501 SEC24B SEC24 homolog B, COPII coat complex component 2 2
MIRT719722 PDE6B phosphodiesterase 6B 2 2
MIRT722204 URM1 ubiquitin related modifier 1 2 2
MIRT723523 CLPTM1L CLPTM1 like 2 2
MIRT725471 GRAP2 GRB2-related adaptor protein 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3622b-3p Platinum 23939 sensitive tissue
hsa-miR-3622b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3622b-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-3622b-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

Error report submission