miRTarBase - #MIRT690103


—
pre-miRNA Information
pre-miRNA hsa-mir-4481   
Genomic Coordinates chr10: 12653138 - 12653197
Description Homo sapiens miR-4481 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4481
Sequence 1| GGAGUGGGCUGGUGGUU |17
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1299710636 5 dbSNP
rs1433739601 12 dbSNP
rs1266754238 14 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PNMA2   
Synonyms MA2, MM2, RGAG2
Description paraneoplastic Ma antigen 2
Transcript NM_007257   
Expression
Putative miRNA Targets on PNMA2
3'UTR of PNMA2
(miRNA target sites are highlighted)		 
>PNMA2|NM_007257|3'UTR
   1 AAACCACCTGGGGGCAGGACCCACAGCCAGTGGGCTAAGACCTTTAAAAAATTTTTTTCTTTAATGTATGGGACTGAAAT
  81 CAAACCATGAAAGCCAATTATTGACCTTCCTTCCTTCCTTCCTTCCCTCCCTTCCTCCTTCTCTCCTTCTCTCCTCCTCT
 161 CTCCTCTCCTCTCCTCTCTTTCCTTCCTTCCTTCCTTTTTTCTTTTTCTCTTTCTTCTTTATTTCTTGGGTCTCACTCTC
 241 ATCACCCAGGCTAGAGTGCAGTGGCACAAAAATCTCGGCTCACTGCAGCCTTGACTTCCCAGGCTCAGGCTCAGGTGATC
 321 CTCACACCTTAGCCTCCCAAGTACCTGGGACTACAGGCACGCACCACCATGCCTAGCTATTCTTTTGTATTTTTGGTAGA
 401 GACAGGGTTTTGCTGTGTTGCTCAGGCTGGTCTGGAACCCCTAGGCTCAAATGATGTGCCCAACTCGGCCTCCCAAAGTG
 481 CTGGGATTACAGGCATGAACCGCCATGCCTGGCCCTTGATTTTTCTTTTTAAGAAAAAAATATCTAGGAGTTTCTTAGAC
 561 CCTATGTAGATTATTAATGAACAAAAGATTAAACTCCAAATATTAAATAGTAAGCCTGAAGGAATCTGAAACACTTGTAC
 641 TTCCAATTTTCTTTAAATAATCCCAAATAGACCAGAATTGGCCCATACCATAGAAGAAAGAATTGGCAGTCAAAAAAAAA
 721 AATACCTTTTGTAATGTTTGAAAAATAAAGCTGTTTGACTTGTCAGGTGTTTTCCTTTCTCAAATCAGCAAATTCTCTCT
 801 GAGTGCCTGGCTTTGTGAGACACTGTACAAGGAGTTACAAGACTACAGCTATAACCTGCAGTTGAGCAGTTATAAACCTA
 881 CAAAATGGGCCCTGCCCTCAGAGAGGTTCCAGTCTAGATGAGGAGCTGATCTAGACAGGTAAAAGGCTAACTAACCCTTT
 961 GTGTAAATAAGTTCATCACCCCAGTAAAAGTGTCATCACCCAGTGAATAGGACCACCTCTGCCTGCAGATTTTTGTTGTT
1041 GTTGTTGTCATTGTTGTTGTTGTTTTAACCTGGGAAGTGTTCTTCCTGCCTTTCTGCTAGGTGTCAGATAGATGGTCCCA
1121 GAGCTAGGTGCTGTGTCAGGCCCTGAAGACACAGATGACTCAACCTAAGCTTTACTTTCCAGAGGTCCACAGCCTGAGAG
1201 GTGTCCCCAAAGAAAGGGGGACATGAGGGGACTGCATGCTTGAGAGCAGGGTTGTTTAGGGCAGGTTTGGATTTAGTGAG
1281 CAGGCTGGTTTGCTTAGAGAAGGCTTTTAGTGGCAACAAAGGATGAAGAGGAGAGAAAAGGAACTCACATTTATTGAGGG
1361 CCTACTGTGTGCAAAGTGTTTCATGTATATCTCATTGAATGTATACAGCCACCCTGTTGTGGTATAATTTTGCTCTTTAT
1441 AAAGAGAAAGACCGAAGCTCAGATGAGTTAAGTGGTCTCCTCAACACCAAAATGCCAAGAAGTGATGGAGCCTAGACAGA
1521 AGCCCAGAACTTTCTGACTCACACTAGTCCATCCTCTACCATCACGATGACTTTCAAATTGTGCTCTGCAGTTCTGCAGA
1601 TTTTCTAGCAGTGCCATCTCCAAAATGTGTTTTAAACTCTTTATTTTTTTAATTATTATTAGTATTATTTTGAGACTGAG
1681 TCTTGCTCTATCACCCAGGCTGGAGTGCAGTGGTGCAATCTCAGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCGATT
1761 TCGTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACCCACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAAA
1841 TGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCCACTCACCTCGGCCTCCCAAAGTGCT
1921 GGGATTACAGGTGTGAGCCACCATGCCTGGGCTAAACTCTTTAAGTCTCTAGTAAATGCAGCTAGATTCAAATGGGCTGA
2001 TAACCAAATTTTAACACATCAGCATTCACCACCAGGTTTACTTTTATTTTCAGATTGGCTCATTTTGTGCAGACCTTAGA
2081 GCAAAGTTTCCTTTATGGTATCTGTGTACGTATCCAAACTTCTTTTAATTGTTCACAGATTTTAAAAGCGGTAGCACCAC
2161 ATGGTTGTGTAGATCAGACCTGTGTATTTAGATCAGACCTGTGTATCACGTAAGTGTGTGAGTGCAGTGCAGATGAGCAC
2241 CATTTAGTTATATGTGCTAGGCAAATCTCCAACACAGTTGATGTGTAGTCTTGTGGTAGATTTGTGCATACTGTAAGCAA
2321 ATTGCTTAGCTTCTCTAGACATCAGTTTCCACATCTGAAAAATAAGAAGATGAGAGTACACGGTTGTTATGAACAAATGA
2401 CTTAATGCTTTTTAAGCACGTTGCATGACATCTGGAACACAGAAAGCCCTCAATACATTGAAGCTCTTAGGATTTTCACG
2481 ATGTTCCTGTCTGCTCAATGCATGCTTTCTTTATTGTTCTGACAGTTGTGTGGTAACAAGCTAATATGCTTCCAGTTGAC
2561 TTCCAGTCTACCCTGGTGTTAGAAACCGTTTCATCTCTTATTGTAAATTTGAGTGCTTGTTGTTTTTTATATTTGTGATG
2641 ACTCTTCCAGCAGTTGTTGACAATTGTTAGAGGTTTGACTTTTAAATAATTACTTATTTTTTCTGATTGTGGTTCAGTTT
2721 AACTGAAGAATATCCTGAGATTGTAAGAAAAGCATTTTTTAAAAGGTATCACTTGTGATCATTTATCTTTCTAAATTCTA
2801 TTTTTAATACTGTTCCACCAAAGTGATGCAGTGGTTACCATGACACCCTAATTTCATGTGTTTTTGTATTTATGAAAATA
2881 GTTTCATTGTCATTTATTGGCGGTATACAAAGTAAAATGTTATAAATGTGAAGTTATAAAATAAATATATGCTAATAAAA
2961 TCCTGAGTTTTTCTGTTTCCT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuGGUGGUC---GGGUGAGg 5'
            || | ||   :|||||| 
Target 5' gaCCTCAAGTGATCCACTCa 3'
 1881 - 1900 131.00 -14.00
2 
miRNA  3' uugguggucGGGUGAGg 5'
                   |:||||| 
Target 5' ttcttgggtCTCACTCt 3'
 223 - 239 124.00 -10.40
3 
miRNA  3' uugguGGUCGGGUGAgg 5'
               :||||:||||  
Target 5' caatcTCAGCTCACTgc 3'
 1716 - 1732 120.00 -17.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30519742 10 COSMIC
COSN26989678 13 COSMIC
COSN30765237 21 COSMIC
COSN31590015 26 COSMIC
COSN31565521 28 COSMIC
COSN30167545 47 COSMIC
COSN19728958 51 COSMIC
COSN14337704 52 COSMIC
COSN30121888 53 COSMIC
COSN31575436 54 COSMIC
COSN26989677 59 COSMIC
COSN31503318 59 COSMIC
COSN26989680 64 COSMIC
COSN30447405 78 COSMIC
COSN18732893 105 COSMIC
COSN31581267 108 COSMIC
COSN30447750 110 COSMIC
COSN30486378 125 COSMIC
COSN14337700 127 COSMIC
COSN30145129 131 COSMIC
COSN30111207 178 COSMIC
COSN30477683 182 COSMIC
COSN6920126 229 COSMIC
COSN27750651 530 COSMIC
COSN2270891 535 COSMIC
COSN20105318 711 COSMIC
COSN27198726 712 COSMIC
COSN32062652 1025 COSMIC
COSN1363176 1028 COSMIC
COSN21108358 1126 COSMIC
COSN25562211 1234 COSMIC
COSN18815997 1419 COSMIC
COSN31962922 1565 COSMIC
COSN19514575 1945 COSMIC
COSN32065507 1999 COSMIC
COSN15568708 2126 COSMIC
COSN28880005 2138 COSMIC
COSN6920125 2241 COSMIC
COSN20076521 2294 COSMIC
COSN19669454 2480 COSMIC
COSN30578187 2495 COSMIC
COSN6599745 2529 COSMIC
COSN26686462 2669 COSMIC
COSN20076440 2680 COSMIC
COSN9629680 2756 COSMIC
COSN7669928 2808 COSMIC
COSN31589115 2823 COSMIC
COSN31588272 2832 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs889142146 3 dbSNP
rs1328407683 4 dbSNP
rs1327158847 9 dbSNP
rs374071599 14 dbSNP
rs1469951493 16 dbSNP
rs764432727 16 dbSNP
rs1347584382 17 dbSNP
rs1322248046 18 dbSNP
rs933436251 20 dbSNP
rs922426465 22 dbSNP
rs760364815 23 dbSNP
rs761327830 24 dbSNP
rs745561699 35 dbSNP
rs972565064 41 dbSNP
rs1438849661 50 dbSNP
rs28619486 51 dbSNP
rs1018676471 52 dbSNP
rs201216184 52 dbSNP
rs1008679777 59 dbSNP
rs1472571035 59 dbSNP
rs888754620 62 dbSNP
rs540030191 64 dbSNP
rs1420451350 68 dbSNP
rs1425872464 72 dbSNP
rs1322464302 79 dbSNP
rs1201489278 85 dbSNP
rs1479384338 91 dbSNP
rs571090953 93 dbSNP
rs1349752428 97 dbSNP
rs1415346843 107 dbSNP
rs969730216 113 dbSNP
rs1332408054 114 dbSNP
rs1023091334 117 dbSNP
rs992581103 121 dbSNP
rs898755350 122 dbSNP
rs960063881 125 dbSNP
rs1039066213 127 dbSNP
rs1482800822 127 dbSNP
rs201014160 127 dbSNP
rs908734063 127 dbSNP
rs1260307694 135 dbSNP
rs1472005151 137 dbSNP
rs1163054701 139 dbSNP
rs1258556535 140 dbSNP
rs1056446931 143 dbSNP
rs1215570349 148 dbSNP
rs762089968 151 dbSNP
rs1031779656 152 dbSNP
rs1313142355 156 dbSNP
rs998994175 156 dbSNP
rs1285812958 169 dbSNP
rs904730213 169 dbSNP
rs1021815425 178 dbSNP
rs1222234308 179 dbSNP
rs968484746 179 dbSNP
rs772399440 182 dbSNP
rs1211766996 188 dbSNP
rs1283021235 191 dbSNP
rs1441199425 196 dbSNP
rs1187234181 197 dbSNP
rs1278941335 198 dbSNP
rs1401900902 202 dbSNP
rs1383127245 208 dbSNP
rs1288508420 210 dbSNP
rs1452867335 212 dbSNP
rs889115391 215 dbSNP
rs1052207351 221 dbSNP
rs1174979194 222 dbSNP
rs1399927075 224 dbSNP
rs547891186 225 dbSNP
rs988486229 225 dbSNP
rs1018801619 227 dbSNP
rs372115541 228 dbSNP
rs897930432 232 dbSNP
rs1295665515 233 dbSNP
rs1364754357 235 dbSNP
rs1235032459 258 dbSNP
rs748566485 262 dbSNP
rs1276723105 274 dbSNP
rs527809445 276 dbSNP
rs953110112 278 dbSNP
rs1285623972 285 dbSNP
rs1449084030 286 dbSNP
rs1429739200 289 dbSNP
rs148035651 290 dbSNP
rs939821193 292 dbSNP
rs909739657 293 dbSNP
rs1259308148 303 dbSNP
rs779106784 304 dbSNP
rs1185556949 314 dbSNP
rs548574412 315 dbSNP
rs994502124 316 dbSNP
rs768963355 328 dbSNP
rs1477430016 333 dbSNP
rs531462372 334 dbSNP
rs562801417 346 dbSNP
rs190452230 348 dbSNP
rs1455395757 349 dbSNP
rs992904740 354 dbSNP
rs1323509089 360 dbSNP
rs1259232357 362 dbSNP
rs749499439 377 dbSNP
rs1031372534 379 dbSNP
rs1441949635 380 dbSNP
rs977166097 382 dbSNP
rs780175407 388 dbSNP
rs887260676 394 dbSNP
rs1324750386 395 dbSNP
rs1294878473 397 dbSNP
rs1056562373 398 dbSNP
rs939407054 400 dbSNP
rs1331844029 401 dbSNP
rs1396834428 404 dbSNP
rs1226898387 412 dbSNP
rs369479351 413 dbSNP
rs1469227058 415 dbSNP
rs1338488217 420 dbSNP
rs578067939 421 dbSNP
rs1264906632 427 dbSNP
rs926704508 430 dbSNP
rs1007778708 438 dbSNP
rs1471588387 443 dbSNP
rs1158084272 450 dbSNP
rs1462856839 464 dbSNP
rs1045163169 467 dbSNP
rs1165218255 469 dbSNP
rs1388864726 470 dbSNP
rs946718137 472 dbSNP
rs915255575 475 dbSNP
rs889369376 481 dbSNP
rs1408512547 484 dbSNP
rs1405319091 492 dbSNP
rs1288311823 495 dbSNP
rs184744015 500 dbSNP
rs191264079 501 dbSNP
rs997938414 502 dbSNP
rs773707141 506 dbSNP
rs1195834096 511 dbSNP
rs1253375766 513 dbSNP
rs865889632 514 dbSNP
rs868771740 515 dbSNP
rs1258221168 519 dbSNP
rs956853178 520 dbSNP
rs911688323 525 dbSNP
rs1036428510 528 dbSNP
rs987309821 530 dbSNP
rs188257294 539 dbSNP
rs1457612781 541 dbSNP
rs1006347066 544 dbSNP
rs1168760034 546 dbSNP
rs1372448109 549 dbSNP
rs1427975617 550 dbSNP
rs768248119 558 dbSNP
rs1307940319 560 dbSNP
rs62492693 561 dbSNP
rs574208973 564 dbSNP
rs1311071606 566 dbSNP
rs1028728707 567 dbSNP
rs1048709916 579 dbSNP
rs1244575425 596 dbSNP
rs781214720 607 dbSNP
rs948623287 610 dbSNP
rs1276386605 614 dbSNP
rs1182173191 615 dbSNP
rs973589555 615 dbSNP
rs183920330 638 dbSNP
rs1280874999 641 dbSNP
rs1015024566 646 dbSNP
rs1179850678 650 dbSNP
rs1255187328 653 dbSNP
rs757105376 654 dbSNP
rs143832051 664 dbSNP
rs1428938278 670 dbSNP
rs1189448042 678 dbSNP
rs1004431249 680 dbSNP
rs1392316078 686 dbSNP
rs751414934 688 dbSNP
rs544197681 690 dbSNP
rs1168046787 698 dbSNP
rs553356849 700 dbSNP
rs924321705 705 dbSNP
rs575172871 706 dbSNP
rs1198090762 709 dbSNP
rs1337940953 710 dbSNP
rs556801304 711 dbSNP
rs76096647 722 dbSNP
rs1035271233 723 dbSNP
rs202158780 723 dbSNP
rs74420816 723 dbSNP
rs1245546438 725 dbSNP
rs540166175 731 dbSNP
rs1362585920 734 dbSNP
rs968447217 745 dbSNP
rs914705175 749 dbSNP
rs1450269373 751 dbSNP
rs986723577 758 dbSNP
rs577486945 760 dbSNP
rs1486062196 765 dbSNP
rs1210367358 777 dbSNP
rs554424252 779 dbSNP
rs1447927838 795 dbSNP
rs1187953080 797 dbSNP
rs1425936262 801 dbSNP
rs1435021830 808 dbSNP
rs144527764 811 dbSNP
rs1174571871 813 dbSNP
rs997801719 815 dbSNP
rs1458042987 817 dbSNP
rs1323002014 828 dbSNP
rs1385925831 838 dbSNP
rs1433872224 840 dbSNP
rs1326217938 860 dbSNP
rs1369091349 861 dbSNP
rs1217024003 864 dbSNP
rs1300428953 865 dbSNP
rs962035262 867 dbSNP
rs1317446817 885 dbSNP
rs1229962083 886 dbSNP
rs1014964789 888 dbSNP
rs893782214 890 dbSNP
rs1006273436 892 dbSNP
rs1394200033 894 dbSNP
rs887863296 907 dbSNP
rs1048201076 911 dbSNP
rs1297127767 912 dbSNP
rs1052867730 917 dbSNP
rs1013153665 919 dbSNP
rs1424708363 920 dbSNP
rs1386777826 922 dbSNP
rs1267195776 926 dbSNP
rs1161266755 930 dbSNP
rs1473217642 935 dbSNP
rs1443568441 941 dbSNP
rs935229093 946 dbSNP
rs541467633 956 dbSNP
rs1165019245 964 dbSNP
rs894333830 968 dbSNP
rs1184371583 969 dbSNP
rs1057420552 979 dbSNP
rs1433589280 995 dbSNP
rs1292470521 996 dbSNP
rs1250400863 1000 dbSNP
rs1411564341 1001 dbSNP
rs1286427844 1002 dbSNP
rs1328221682 1002 dbSNP
rs938637049 1007 dbSNP
rs1290788586 1012 dbSNP
rs1323736720 1013 dbSNP
rs17055367 1019 dbSNP
rs921776131 1022 dbSNP
rs1184962446 1025 dbSNP
rs1250317578 1038 dbSNP
rs1472434146 1046 dbSNP
rs1403272138 1049 dbSNP
rs1415455156 1049 dbSNP
rs963462191 1049 dbSNP
rs973154889 1049 dbSNP
rs1370606728 1050 dbSNP
rs1289943794 1051 dbSNP
rs372296756 1052 dbSNP
rs769647857 1053 dbSNP
rs947115283 1056 dbSNP
rs1349812839 1060 dbSNP
rs1448400200 1064 dbSNP
rs1279957506 1065 dbSNP
rs914320430 1088 dbSNP
rs985926486 1097 dbSNP
rs192844303 1108 dbSNP
rs923502179 1116 dbSNP
rs1207397953 1121 dbSNP
rs1333958284 1124 dbSNP
rs1451596296 1127 dbSNP
rs959740588 1142 dbSNP
rs368944026 1152 dbSNP
rs1211206034 1155 dbSNP
rs1239560386 1156 dbSNP
rs962294679 1172 dbSNP
rs1242870482 1175 dbSNP
rs781087667 1179 dbSNP
rs1366908435 1184 dbSNP
rs1300669600 1185 dbSNP
rs1390465481 1187 dbSNP
rs1450730899 1188 dbSNP
rs1166180505 1202 dbSNP
rs188057893 1211 dbSNP
rs34150506 1221 dbSNP
rs569188997 1222 dbSNP
rs1035213583 1224 dbSNP
rs1014892727 1226 dbSNP
rs1336133485 1227 dbSNP
rs1357208666 1228 dbSNP
rs552029351 1229 dbSNP
rs1003777016 1234 dbSNP
rs1314555845 1239 dbSNP
rs1366201789 1242 dbSNP
rs952056039 1244 dbSNP
rs1192940888 1247 dbSNP
rs1295520535 1259 dbSNP
rs1160699419 1262 dbSNP
rs1468899680 1265 dbSNP
rs532293716 1274 dbSNP
rs1012374115 1281 dbSNP
rs1010951440 1282 dbSNP
rs1441039406 1284 dbSNP
rs1200187554 1288 dbSNP
rs1248188721 1303 dbSNP
rs894294767 1308 dbSNP
rs1052564567 1310 dbSNP
rs1266871755 1313 dbSNP
rs935326584 1324 dbSNP
rs1221793269 1325 dbSNP
rs890489312 1343 dbSNP
rs1051652490 1344 dbSNP
rs142761267 1348 dbSNP
rs1321010999 1354 dbSNP
rs1206744208 1355 dbSNP
rs931905615 1357 dbSNP
rs4872448 1358 dbSNP
rs1325930882 1372 dbSNP
rs183466082 1401 dbSNP
rs903127386 1406 dbSNP
rs1277062799 1407 dbSNP
rs561035016 1412 dbSNP
rs544011099 1413 dbSNP
rs1343499178 1414 dbSNP
rs1041336994 1421 dbSNP
rs1269187611 1422 dbSNP
rs1403771246 1425 dbSNP
rs941909547 1435 dbSNP
rs369525532 1448 dbSNP
rs575155174 1449 dbSNP
rs115426035 1450 dbSNP
rs397735433 1452 dbSNP
rs57333903 1452 dbSNP
rs907617489 1452 dbSNP
rs192918485 1453 dbSNP
rs959683844 1454 dbSNP
rs892825504 1461 dbSNP
rs1477668221 1467 dbSNP
rs1159876814 1478 dbSNP
rs777662707 1479 dbSNP
rs1455507658 1504 dbSNP
rs1050596596 1517 dbSNP
rs1384720829 1522 dbSNP
rs1384547637 1523 dbSNP
rs1387359553 1524 dbSNP
rs1177523030 1527 dbSNP
rs1325646448 1529 dbSNP
rs1329808842 1531 dbSNP
rs1404855428 1537 dbSNP
rs1471262048 1546 dbSNP
rs931783552 1548 dbSNP
rs1427757172 1554 dbSNP
rs546486779 1564 dbSNP
rs138708461 1565 dbSNP
rs923398331 1566 dbSNP
rs1244113349 1601 dbSNP
rs1191321387 1604 dbSNP
rs554362701 1610 dbSNP
rs976249311 1616 dbSNP
rs1211056483 1622 dbSNP
rs1287103159 1627 dbSNP
rs1446572009 1637 dbSNP
rs1490056005 1648 dbSNP
rs145849792 1650 dbSNP
rs958270229 1655 dbSNP
rs1471456680 1658 dbSNP
rs1181194775 1662 dbSNP
rs1363398833 1663 dbSNP
rs908135967 1664 dbSNP
rs1031490793 1672 dbSNP
rs1165270098 1672 dbSNP
rs1204005291 1688 dbSNP
rs985067045 1690 dbSNP
rs1424159477 1692 dbSNP
rs1309107134 1696 dbSNP
rs189009277 1709 dbSNP
rs1408341865 1720 dbSNP
rs35859855 1720 dbSNP
rs1306760264 1725 dbSNP
rs758482059 1728 dbSNP
rs1023672799 1731 dbSNP
rs768099151 1732 dbSNP
rs1282139630 1735 dbSNP
rs56024323 1739 dbSNP
rs1339463377 1740 dbSNP
rs1205274819 1742 dbSNP
rs1271375158 1748 dbSNP
rs779100139 1752 dbSNP
rs61343394 1753 dbSNP
rs1002676441 1756 dbSNP
rs903053798 1757 dbSNP
rs533672827 1762 dbSNP
rs183568831 1763 dbSNP
rs1189861091 1764 dbSNP
rs1366948569 1772 dbSNP
rs1454896485 1773 dbSNP
rs1169338822 1775 dbSNP
rs892785669 1777 dbSNP
rs1050101668 1778 dbSNP
rs1298141420 1784 dbSNP
rs565638780 1785 dbSNP
rs1398220176 1794 dbSNP
rs1410962317 1796 dbSNP
rs907728327 1804 dbSNP
rs901610157 1806 dbSNP
rs1040533866 1809 dbSNP
rs538503910 1810 dbSNP
rs1339517902 1817 dbSNP
rs1184010490 1849 dbSNP
rs1346570621 1852 dbSNP
rs940822474 1855 dbSNP
rs189766331 1865 dbSNP
rs908081888 1868 dbSNP
rs985036039 1870 dbSNP
rs1241485549 1872 dbSNP
rs546535578 1873 dbSNP
rs928262813 1879 dbSNP
rs1392062963 1884 dbSNP
rs1307940791 1893 dbSNP
rs1426881847 1894 dbSNP
rs916530138 1896 dbSNP
rs1170346819 1899 dbSNP
rs979744862 1904 dbSNP
rs1212248748 1905 dbSNP
rs1467844002 1908 dbSNP
rs1338403642 1912 dbSNP
rs1301494996 1917 dbSNP
rs186936432 1931 dbSNP
rs758503904 1932 dbSNP
rs560954162 1942 dbSNP
rs112394097 1945 dbSNP
rs1362397388 1948 dbSNP
rs769956643 1957 dbSNP
rs1035055138 1962 dbSNP
rs978170145 1964 dbSNP
rs1443601055 1969 dbSNP
rs967180766 1970 dbSNP
rs1262250789 1979 dbSNP
rs137896417 1985 dbSNP
rs1011873810 1988 dbSNP
rs957310737 2010 dbSNP
rs1029050531 2017 dbSNP
rs1484902882 2018 dbSNP
rs995868388 2029 dbSNP
rs1031187482 2041 dbSNP
rs550397970 2053 dbSNP
rs150495711 2062 dbSNP
rs182358057 2065 dbSNP
rs1409416335 2067 dbSNP
rs954783774 2070 dbSNP
rs545026964 2075 dbSNP
rs140578845 2082 dbSNP
rs1165694135 2086 dbSNP
rs1160849106 2090 dbSNP
rs1442950677 2098 dbSNP
rs996175418 2109 dbSNP
rs1181031059 2110 dbSNP
rs1004670532 2111 dbSNP
rs1234512744 2133 dbSNP
rs867203176 2149 dbSNP
rs2197181 2150 dbSNP
rs1291795675 2156 dbSNP
rs1350868400 2157 dbSNP
rs151302692 2161 dbSNP
rs1270180373 2164 dbSNP
rs1356773113 2181 dbSNP
rs1314818489 2182 dbSNP
rs916851759 2184 dbSNP
rs1224659629 2188 dbSNP
rs1376212865 2191 dbSNP
rs1006152771 2193 dbSNP
rs1441635685 2195 dbSNP
rs1266086970 2196 dbSNP
rs1366292181 2196 dbSNP
rs1304965842 2198 dbSNP
rs1423011892 2202 dbSNP
rs1197888911 2207 dbSNP
rs17055364 2210 dbSNP
rs939349314 2215 dbSNP
rs1405283186 2216 dbSNP
rs554884245 2224 dbSNP
rs1165084662 2225 dbSNP
rs1351108788 2232 dbSNP
rs978138959 2233 dbSNP
rs1302409023 2235 dbSNP
rs1371095831 2238 dbSNP
rs73558907 2250 dbSNP
rs1286255099 2252 dbSNP
rs1372411660 2254 dbSNP
rs913027534 2258 dbSNP
rs990015626 2259 dbSNP
rs1313787415 2264 dbSNP
rs373902128 2272 dbSNP
rs1044164382 2281 dbSNP
rs1410157647 2283 dbSNP
rs957485823 2293 dbSNP
rs1215110970 2296 dbSNP
rs1483680640 2299 dbSNP
rs141309385 2306 dbSNP
rs1231498315 2320 dbSNP
rs1470003511 2321 dbSNP
rs1487436728 2325 dbSNP
rs1245088456 2328 dbSNP
rs1220845118 2333 dbSNP
rs996538217 2341 dbSNP
rs759564773 2349 dbSNP
rs558474977 2363 dbSNP
rs1162414538 2371 dbSNP
rs538644127 2371 dbSNP
rs1310149014 2374 dbSNP
rs886207534 2374 dbSNP
rs1428462211 2378 dbSNP
rs936940626 2381 dbSNP
rs146585033 2382 dbSNP
rs924070754 2387 dbSNP
rs1232262130 2390 dbSNP
rs1353398206 2395 dbSNP
rs1355571093 2395 dbSNP
rs552826556 2396 dbSNP
rs978246377 2398 dbSNP
rs1303586919 2400 dbSNP
rs995004513 2402 dbSNP
rs777687724 2419 dbSNP
rs1343014055 2424 dbSNP
rs1231245869 2434 dbSNP
rs1228328332 2438 dbSNP
rs974850107 2445 dbSNP
rs965044599 2450 dbSNP
rs1346653647 2453 dbSNP
rs1238808739 2456 dbSNP
rs1055377728 2457 dbSNP
rs1248076806 2458 dbSNP
rs1450869487 2464 dbSNP
rs1166078683 2470 dbSNP
rs1403159734 2474 dbSNP
rs939631525 2479 dbSNP
rs1177990145 2480 dbSNP
rs1403694315 2486 dbSNP
rs1450678534 2487 dbSNP
rs1026223925 2493 dbSNP
rs1289661952 2494 dbSNP
rs1454172083 2496 dbSNP
rs536177904 2500 dbSNP
rs567421852 2503 dbSNP
rs945436856 2504 dbSNP
rs1456658885 2508 dbSNP
rs550512517 2526 dbSNP
rs1265361774 2541 dbSNP
rs543518618 2554 dbSNP
rs1044112369 2566 dbSNP
rs1248325060 2573 dbSNP
rs948516066 2579 dbSNP
rs915338162 2587 dbSNP
rs17055361 2588 dbSNP
rs761723133 2590 dbSNP
rs765002256 2592 dbSNP
rs144274517 2594 dbSNP
rs1192888097 2599 dbSNP
rs1426931546 2601 dbSNP
rs1266298656 2604 dbSNP
rs974654964 2608 dbSNP
rs978360894 2619 dbSNP
rs933460292 2629 dbSNP
rs1325980510 2632 dbSNP
rs139556086 2633 dbSNP
rs1285829551 2635 dbSNP
rs1344015398 2644 dbSNP
rs1223298739 2646 dbSNP
rs1268300147 2648 dbSNP
rs1352422036 2659 dbSNP
rs1018600366 2670 dbSNP
rs1451739654 2672 dbSNP
rs1223655175 2673 dbSNP
rs983129166 2693 dbSNP
rs1479949192 2697 dbSNP
rs765783828 2697 dbSNP
rs1027388847 2699 dbSNP
rs1265510017 2707 dbSNP
rs528080504 2712 dbSNP
rs1406087671 2713 dbSNP
rs559415760 2716 dbSNP
rs995035369 2722 dbSNP
rs1305434934 2734 dbSNP
rs762450332 2737 dbSNP
rs1289349722 2743 dbSNP
rs1337940456 2745 dbSNP
rs1034270016 2754 dbSNP
rs145706580 2771 dbSNP
rs373917381 2775 dbSNP
rs1384166616 2777 dbSNP
rs1042338579 2778 dbSNP
rs1026171516 2780 dbSNP
rs191314113 2793 dbSNP
rs907021438 2796 dbSNP
rs1022755284 2799 dbSNP
rs1205847173 2807 dbSNP
rs1013047124 2813 dbSNP
rs893830407 2817 dbSNP
rs879589611 2818 dbSNP
rs892877612 2823 dbSNP
rs1179915577 2826 dbSNP
rs1053869453 2828 dbSNP
rs1165586255 2838 dbSNP
rs779837371 2838 dbSNP
rs932738025 2841 dbSNP
rs1468111306 2856 dbSNP
rs921749854 2858 dbSNP
rs1309234807 2861 dbSNP
rs1399059373 2867 dbSNP
rs975002838 2874 dbSNP
rs1390041376 2883 dbSNP
rs6557925 2888 dbSNP
rs1429955810 2897 dbSNP
rs1259208997 2901 dbSNP
rs186362650 2902 dbSNP
rs1462043951 2903 dbSNP
rs983392102 2908 dbSNP
rs575478654 2912 dbSNP
rs558616642 2918 dbSNP
rs1202343359 2921 dbSNP
rs1195018988 2928 dbSNP
rs1250037366 2936 dbSNP
rs563852974 2939 dbSNP
rs1241349346 2952 dbSNP
rs1444144154 2953 dbSNP
rs1169714982 2955 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uugguggucGGGUGAGg 5'
                   :|||||| 
Target 5' ------ugaUCCACUCa 3'
 		1 - 11
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM4903829
Method / RBP HITS-CLIP / AGO
Cell line / Condition Human neurons / CTLTD_shCTL_a
Location of target site NM_007257 | 3UTR | CACUCACCUCGGCCUCCCAAAGUGCUGGGAUUACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161238
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_007257 | 3UTR | ACCACCACGCCCAGCUAAUUUUUGUAUUUUUAGUAGAAAUGGGGUUUCACCAUGUUGGCCAGGCUGGUCUCGAACUCCUGACCUCAAGUGAUCCACUCACCUCGGCCUCCCAAAGUGCUGGGAUUACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_007257 | 3UTR | ACGCCCAGCUAAUUUUUGUAUUUUUAGUAGAAAUGGGGUUUCACCAUGUUGGCCAGGCUGGUCUCGAACUCCUGACCUCAAGUGAUCCACUCACCUCGGCCUCCCAAAGUGCUGGGAUUACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_007257 | 3UTR | CUCCCGAGUAGCUGGGAUUACAGGCACCCACCACCACGCCCAGCUAAUUUUUGUAUUUUUAGUAGAAAUGGGGUUUCACCAUGUUGGCCAGGCUGGUCUCGAACUCCUGACCUCAAGUGAUCCACUCACCUCGGCCUCCCAAAGUGCUGGGAUUACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_007257 | 3UTR | CCCAGCUAAUUUUUGUAUUUUUAGUAGAAAUGGGGUUUCACCAUGUUGGCCAGGCUGGUCUCGAACUCCUGACCUCAAGUGAUCCACUCACCUCGGCCUCCCAAAGUGCUGGGAUUACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_007257 | 3UTR | UGGGAUUACAGGCACCCACCACCACGCCCAGCUAAUUUUUGUAUUUUUAGUAGAAAUGGGGUUUCACCAUGUUGGCCAGGCUGGUCUCGAACUCCUGACCUCAAGUGAUCCACUCACCUCGGCCUCCCAAAGUGCUGGGAUUACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_007257 | 3UTR | ACUCCUGACCUCAAGUGAUCCACUCACCUCGGCCUCCCAAAGUGCUGGGAUUACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000522362.2 | 3UTR | UGAUCCACUCACCUCGGCCUCCCAAAGUGCUGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
84 hsa-miR-4481 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT100715 TJAP1 tight junction associated protein 1 2 2
MIRT183589 ZC3H11A zinc finger CCCH-type containing 11A 2 2
MIRT338033 DAZAP2 DAZ associated protein 2 2 4
MIRT395796 SPCS3 signal peptidase complex subunit 3 2 2
MIRT443947 LRIT3 leucine rich repeat, Ig-like and transmembrane domains 3 2 2
MIRT450580 HIST1H2BG histone cluster 1 H2B family member g 2 6
MIRT451617 MEIS3P1 Meis homeobox 3 pseudogene 1 2 2
MIRT452331 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT453279 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT455212 GNL1 G protein nucleolar 1 (putative) 2 2
MIRT455470 LYPLA2 lysophospholipase II 2 2
MIRT456503 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2 2
MIRT456687 LDB1 LIM domain binding 1 2 2
MIRT456915 DDA1 DET1 and DDB1 associated 1 2 2
MIRT457603 IDS iduronate 2-sulfatase 2 2
MIRT457848 RNASEH2B ribonuclease H2 subunit B 2 4
MIRT458455 RPRM reprimo, TP53 dependent G2 arrest mediator homolog 2 2
MIRT460179 UNK unkempt family zinc finger 2 6
MIRT461465 SLC19A3 solute carrier family 19 member 3 2 2
MIRT464739 UBE2Q1 ubiquitin conjugating enzyme E2 Q1 2 2
MIRT465279 TRIM28 tripartite motif containing 28 2 2
MIRT468450 SETD1B SET domain containing 1B 2 2
MIRT468620 SUMO1 small ubiquitin-like modifier 1 2 6
MIRT469152 RNF121 ring finger protein 121 2 2
MIRT470073 PTGES2 prostaglandin E synthase 2 2 2
MIRT470172 PSMD11 proteasome 26S subunit, non-ATPase 11 2 4
MIRT473156 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT474308 LAMC1 laminin subunit gamma 1 2 2
MIRT474782 KIAA0895L KIAA0895 like 2 2
MIRT476484 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT477613 EFNA3 ephrin A3 2 2
MIRT479525 CDCA4 cell division cycle associated 4 2 2
MIRT479973 CARD10 caspase recruitment domain family member 10 2 2
MIRT480410 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480426 C17orf85 nuclear cap binding subunit 3 2 2
MIRT483573 SYT2 synaptotagmin 2 2 2
MIRT483664 QSOX2 quiescin sulfhydryl oxidase 2 2 4
MIRT484532 POLD3 DNA polymerase delta 3, accessory subunit 2 2
MIRT484616 SIX3 SIX homeobox 3 2 6
MIRT485897 ZFP36 ZFP36 ring finger protein 2 2
MIRT486505 MYH11 myosin heavy chain 11 2 2
MIRT487505 GRK5 G protein-coupled receptor kinase 5 2 2
MIRT488852 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489464 MSC musculin 2 2
MIRT491170 LRP3 LDL receptor related protein 3 2 2
MIRT496627 TMEM67 transmembrane protein 67 2 2
MIRT497616 ANG angiogenin 2 2
MIRT497766 KIAA0895 KIAA0895 2 2
MIRT499680 MRE11A MRE11 homolog, double strand break repair nuclease 2 6
MIRT499774 SLC29A2 solute carrier family 29 member 2 2 2
MIRT501745 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT504995 ZNF652 zinc finger protein 652 2 2
MIRT511664 HIST1H3C histone cluster 1 H3 family member c 2 2
MIRT511690 HIST1H2BO histone cluster 1 H2B family member o 2 4
MIRT511703 HIST1H2BL histone cluster 1 H2B family member l 2 4
MIRT511734 HIST1H2BE histone cluster 1 H2B family member e 2 8
MIRT512858 TBC1D13 TBC1 domain family member 13 2 2
MIRT513444 EMP1 epithelial membrane protein 1 2 6
MIRT515681 TFPI tissue factor pathway inhibitor 2 2
MIRT523529 GLUL glutamate-ammonia ligase 2 2
MIRT525546 PHB2 prohibitin 2 2 4
MIRT526209 SNX24 sorting nexin 24 2 2
MIRT531554 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT533764 TMEM135 transmembrane protein 135 2 2
MIRT545582 SNRPA1 small nuclear ribonucleoprotein polypeptide A' 2 2
MIRT552434 ZNF460 zinc finger protein 460 2 2
MIRT561159 BCL2L12 BCL2 like 12 2 2
MIRT562345 EXOSC2 exosome component 2 2 2
MIRT570659 KDM6B lysine demethylase 6B 2 2
MIRT571076 TCHHL1 trichohyalin like 1 2 2
MIRT571330 TPCN2 two pore segment channel 2 2 2
MIRT571603 TOB2 transducer of ERBB2, 2 2 2
MIRT573013 RPP25 ribonuclease P and MRP subunit p25 2 2
MIRT609041 EP300 E1A binding protein p300 2 2
MIRT613398 DNAH17 dynein axonemal heavy chain 17 2 2
MIRT635589 TTC9C tetratricopeptide repeat domain 9C 2 2
MIRT661118 FPR1 formyl peptide receptor 1 2 2
MIRT690103 PNMA2 paraneoplastic Ma antigen 2 2 2
MIRT694972 PLAC8 placenta specific 8 2 2
MIRT695515 ALPI alkaline phosphatase, intestinal 2 2
MIRT695578 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT699570 SIT1 signaling threshold regulating transmembrane adaptor 1 2 2
MIRT701991 MIER3 MIER family member 3 2 2
MIRT725464 GRAP2 GRB2-related adaptor protein 2 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4481 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-mir-4481 Androstenedione 6128 NSC9563 sensitive cell line (MCF-7)
hsa-mir-4481 Tamoxifen 2733525 NSC180973 approved resistant cell line (MCF7)
hsa-mir-4481 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4481 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (cytosolic RNA)
hsa-miR-4481 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4481 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4481 Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-4481 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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