miRTarBase - #MIRT694845


—
pre-miRNA Information
pre-miRNA hsa-mir-151b   
Genomic Coordinates chr14: 100109419 - 100109514
Description Homo sapiens miR-151b stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-151b
Sequence 60| UCGAGGAGCUCACAGUCU |77
Evidence Experimental
Experiments RAKE
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs530616727 2 dbSNP
rs1447689330 3 dbSNP
rs1167577108 16 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol KRT80   
Synonyms KB20
Description keratin 80
Transcript NM_001081492   
Other Transcripts NM_182507   
Expression
Putative miRNA Targets on KRT80
3'UTR of KRT80
(miRNA target sites are highlighted)		 
>KRT80|NM_001081492|3'UTR
   1 CTGCCTCCAGATCAGGCCTCTCCAAGGCCCCCTCCCGAAAGAAGAAGGGCAGCAAAGGCCCCGTGATCAAAATCACCGAA
  81 ATGTCAGAGAAGTACTTCTCGCAGGAGTCGGAGGTCTCAGAGTAAGGCGGCTGGACCCCAGGAACCCCAGGGCACTCCAC
 161 TGCAGCAGGAGGGACTTAAGCTAGACTCAAGAAAGCAGCTTGGAGCCTCTAGGTTGAGAAGAGAGGCAAAACCTGATATT
 241 GAACTGAGAGAGGGGTTCAAAACTGACTGTGTTTTGTGGGCTGCCAGGGTGGGAGAGGAGCATCACCAGCTCCTCAGAGC
 321 CACTCCGCTCCATATCAGTATCTCACAGTCCCATCCTTCCAACCTTCTGGCCAGAGGTTTTCCTGATGGGTGAGTCGGAA
 401 TTAGGGGTCAGTTTTGTCTCCACCTCCTCGCTCCTCTGAGGCTCCTCCTCCAGCATCAGGCTCTGCCAAGGCCCCTCTGA
 481 CTCTTGCCCAATCCTTGACCTTGACTCCTATCTCAAGCCTTGCCTTGTCTCTGCCTCGGAACTGGGACTGGGACTGGCTC
 561 ATCCACCTATGTGCGGGAGCCGAGGAGGACGGCGTGGGCCCTGTCCTGTATCTGGAATTCCTGGGAAGGCTGGCTGCTGA
 641 AGACCCTCTTGGCTTTCCCGTGCTCTTTGGGCTCCCCAGAGACCTGACAGTATTAGGGAGTGAAGGGAGGAGGGGCCCTG
 721 GCTATTTGGGACCTAAGCCTAGGCCCCAGAGATCAGCCCGAACACCCGCATCCCTTCCTCCTCCCATGGGTCCCTCCCAG
 801 TAGGCAGTAGTCAGAACTGGATGGGCTGCCCCCAGCCAGCTCCCAGCAGCTTCTCCGGAAGCTGCTCTTGCCATAATCAA
 881 CTCCCTGGGAGTGGAAGCCAGATGGCAGCTTGAGATTGGGCAGGAGCATTCGATCTTCCTTTCACCTCCCTGCCATGCTG
 961 GGGTCCTACCCAGCCTGGATCTGAGCTCTGTGCCCCCAGCCGGGTTGTTCCCAGCCTGAGCACCGGGCTTTGGTGCACCA
1041 GGCCTTGGAGACCCCTGGTCCCACCCCTGCCGTGAAGCCCCAGGCCCACTTCCCAAGAATCTCACTTCTCAGGGCCTCTG
1121 TTCTCCTCTCCACTGGGCCAAATAGCCTGGCCCTCCCCTCCTTGGCATTCATGGGGGAGCCCAGGAACCCCCCACACCTA
1201 TGGGGTTAGAGCTCCTCCTTTCTTCTCACTCCTTCCCCTTCCTCCCTCCATGCCCACTCCCCCTGCCTCCAGCAGGCCAG
1281 GAAGAAGGCACAGTCCAGGCAAGTCTGGGAGCTTCCAAGCCCTTGAGGTCCAGCTGTGGGGCCCAAATGACAGCCTTACA
1361 AGGGTTCTACCAGAGAGGAAAATTCCACATCCCACCAGAAGACAGGGGTGTTGGCAGGCATACTCCTATCTCCTCCTCTT
1441 GGCTCTCAATGCTGAGGCTTGCAGAGGCATCCCAGCGGCACCAGCCTCCCACTGCACAGCTTCCTTCCCTCCTTCACTCT
1521 CCTCTCCCCTCCCTGCCCCTTGCCTCACCTCCTCTTCTAGACTGCATTAGATTCATTCATCTCATTTGCCAGGACATGTT
1601 GGCCAGAGGTCTGGGCCCATCCCAGGCCTCAAGGCCCTCCAGGCCTGTGGGGAGCACTGGAGGGTTACTGACTCTCTGGC
1681 CATGGGAACTCAGAGATTCTCATCCCCAAAGTCCCAAAAGAGGGTGCTGATTGGTGCTTTTCCTCAGGCTCTTCATTGGT
1761 TTCCAAGGGAGCAAATCCTCAGTGGGGATACAAGACATATAAAGTATATATTATTTTTTCATAACTTATGTGGCTTTTAA
1841 CTTATTGCTTCCCTTCCTGTTTCTGCATGATCAGTCTGTATGTACTATCTGGAAAGATAACACATACTCCAGCCACCTCA
1921 CCTGATTGGCTATCTTGGGGCCATGTCCCCTTCTTGCTGCCACAGGATGAATAAAGTGTTGAGATTTGTCTATGGAGAAA
2001 GCTGTGTGTCTGTTTTTATCTCCCCTCTCAGGACCAGTCAGCCACTGGTCAATCAGGCTGATCATGGAACATTAGGAATT
2081 CTCCAATTAAGGGAGAAAAAGTCCAGGGACTTAGTTATATCTTCAGACCAGTGCAGCTGGTACACACAAAGTTCTCCTGT
2161 CTCACCATCTGATATGGTTTGGATGCTCGTCCCCTCCAAATCTCATGTTGAAATGTAATTCCCAGTGTTGGAAGTGGAGC
2241 CTGGTGGGAAGTATTTGGATCATGAGAGAGGATCCTTCATGAATGGCTCAGCACCATCTCCTTGGTGATGAGTGAGTTCT
2321 CACTCAATTCACATAGATATGGTTGTTTAAAAGAGTCTGAGACCTCTCCCCTCTTTCTCGCCATGTGATATGCCTGCTCC
2401 CCCTTCACCTTCCGCCTTTACTGTAAGCTTCCTGAGGCCCTCACCAGAAGCTGAGCAAATGTTGGTGCCATGCCAGTACA
2481 GCCTGCAGAATTGTGAGCCAAAATAAATGTCTTTTCTTTATAAATTA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucuGACA---CUCGAGGAGCu 5'
             :|||    | ||||||| 
Target 5' gttTTGTCTCCACCTCCTCGc 3'
 411 - 431 143.00 -11.80
2 
miRNA  3' ucugacaCUCGAGGAGcu 5'
                 |||||||||  
Target 5' ggggttaGAGCTCCTCct 3'
 1202 - 1219 135.00 -15.70
3 
miRNA  3' ucuGACACUC----GAGGAGcu 5'
             || ||||    ||||||  
Target 5' ctcCTCTGAGGCTCCTCCTCca 3'
 431 - 452 133.00 -13.44
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM7830180 7 COSMIC
COSM3359798 10 COSMIC
COSM5841271 15 COSMIC
COSM4797392 16 COSMIC
COSM4462588 18 COSMIC
COSM3398818 26 COSMIC
COSM8751011 30 COSMIC
COSM5596951 32 COSMIC
COSM4042798 34 COSMIC
COSM9689065 35 COSMIC
COSM3462171 36 COSMIC
COSM6137022 36 COSMIC
COSM9047606 36 COSMIC
COSM389050 37 COSMIC
COSM3871846 43 COSMIC
COSM4696897 59 COSMIC
COSM5533562 65 COSMIC
COSM940645 77 COSMIC
COSM2010148 78 COSMIC
COSM7092667 89 COSMIC
COSM6137024 91 COSMIC
COSM8320176 98 COSMIC
COSM9405704 100 COSMIC
COSM4333179 101 COSMIC
COSM8018340 105 COSMIC
COSM940643 110 COSMIC
COSM6502473 120 COSMIC
COSN30188941 157 COSMIC
COSN31594679 159 COSMIC
COSN31557970 191 COSMIC
COSN30149186 216 COSMIC
COSN30149163 221 COSMIC
COSN31568884 229 COSMIC
COSN30125607 254 COSMIC
COSN18736931 287 COSMIC
COSN31516616 320 COSMIC
COSN31595806 621 COSMIC
COSN31485246 727 COSMIC
COSN31564480 767 COSMIC
COSN30542707 774 COSMIC
COSN28645473 858 COSMIC
COSN9083737 1166 COSMIC
COSN23987737 1454 COSMIC
COSN31959593 1570 COSMIC
COSN30056278 1616 COSMIC
COSN5946042 1679 COSMIC
COSN5323933 1720 COSMIC
COSN20872499 1777 COSMIC
COSN1576123 2038 COSMIC
COSN5946041 2042 COSMIC
COSN31533959 2106 COSMIC
COSN22007245 2233 COSMIC
COSN9563209 2268 COSMIC
COSN1149191 2333 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs988484980 12 dbSNP
rs1441777103 17 dbSNP
rs1344134232 19 dbSNP
rs1158987422 20 dbSNP
rs1396775620 22 dbSNP
rs773092935 26 dbSNP
rs767452126 28 dbSNP
rs761818433 32 dbSNP
rs774487570 36 dbSNP
rs201244168 37 dbSNP
rs748764577 44 dbSNP
rs1488836993 45 dbSNP
rs778803660 48 dbSNP
rs1412910858 49 dbSNP
rs139622526 50 dbSNP
rs769435584 51 dbSNP
rs756823818 52 dbSNP
rs202050803 62 dbSNP
rs146047066 63 dbSNP
rs75380871 69 dbSNP
rs757670176 72 dbSNP
rs747504116 77 dbSNP
rs778323464 78 dbSNP
rs758837904 83 dbSNP
rs1429151239 85 dbSNP
rs202009004 86 dbSNP
rs1002565167 87 dbSNP
rs1197124106 88 dbSNP
rs1160298690 89 dbSNP
rs1469637573 92 dbSNP
rs1273300378 93 dbSNP
rs746090926 96 dbSNP
rs765254834 97 dbSNP
rs1254720340 98 dbSNP
rs755188804 99 dbSNP
rs74095220 100 dbSNP
rs569276446 101 dbSNP
rs886981862 102 dbSNP
rs761765067 103 dbSNP
rs370662279 104 dbSNP
rs1321125852 106 dbSNP
rs76226247 109 dbSNP
rs146327143 110 dbSNP
rs775021765 111 dbSNP
rs1246092570 113 dbSNP
rs141488153 114 dbSNP
rs1230003902 118 dbSNP
rs1367921855 123 dbSNP
rs201045264 128 dbSNP
rs776326918 129 dbSNP
rs1404360322 130 dbSNP
rs1304967443 131 dbSNP
rs1328801101 134 dbSNP
rs771283392 144 dbSNP
rs747311502 145 dbSNP
rs1255137032 147 dbSNP
rs890884929 151 dbSNP
rs200099091 152 dbSNP
rs372656260 154 dbSNP
rs369106763 155 dbSNP
rs1459974860 157 dbSNP
rs748634796 159 dbSNP
rs1200831379 162 dbSNP
rs1480078794 166 dbSNP
rs1249290734 167 dbSNP
rs945777979 169 dbSNP
rs376004589 174 dbSNP
rs947311637 180 dbSNP
rs1468757823 184 dbSNP
rs914376693 186 dbSNP
rs914110130 201 dbSNP
rs955771224 203 dbSNP
rs878953178 213 dbSNP
rs1035475075 225 dbSNP
rs575441541 227 dbSNP
rs936963481 245 dbSNP
rs1364247075 253 dbSNP
rs187531530 255 dbSNP
rs146704426 258 dbSNP
rs1389169221 263 dbSNP
rs778848636 283 dbSNP
rs183034874 284 dbSNP
rs12818603 287 dbSNP
rs917914464 295 dbSNP
rs1339275389 312 dbSNP
rs1397682534 318 dbSNP
rs992236471 321 dbSNP
rs548356839 326 dbSNP
rs951531653 327 dbSNP
rs1016421547 329 dbSNP
rs1199023803 330 dbSNP
rs1005081239 335 dbSNP
rs1352737009 338 dbSNP
rs1487154486 346 dbSNP
rs1205715755 348 dbSNP
rs1263911925 350 dbSNP
rs1261774696 351 dbSNP
rs1216050848 368 dbSNP
rs1351562048 370 dbSNP
rs1475682666 374 dbSNP
rs1025498127 385 dbSNP
rs112639193 387 dbSNP
rs1317516252 388 dbSNP
rs995722019 396 dbSNP
rs962669612 397 dbSNP
rs1159662912 405 dbSNP
rs1359295898 407 dbSNP
rs1018167897 416 dbSNP
rs1314216910 425 dbSNP
rs886513313 429 dbSNP
rs527615142 430 dbSNP
rs561986337 434 dbSNP
rs1006566705 436 dbSNP
rs998013761 440 dbSNP
rs1239608972 441 dbSNP
rs34390544 452 dbSNP
rs542111879 465 dbSNP
rs1285254663 466 dbSNP
rs1353029867 470 dbSNP
rs900468746 475 dbSNP
rs1310322427 491 dbSNP
rs890837463 497 dbSNP
rs1050743203 501 dbSNP
rs1282627347 507 dbSNP
rs1483697388 510 dbSNP
rs576514298 510 dbSNP
rs1010020477 512 dbSNP
rs891522915 517 dbSNP
rs1052636464 525 dbSNP
rs1254431543 537 dbSNP
rs1421267721 538 dbSNP
rs1179768701 539 dbSNP
rs1380192751 546 dbSNP
rs1039460849 547 dbSNP
rs1383668469 548 dbSNP
rs1438438889 550 dbSNP
rs947283800 551 dbSNP
rs191205037 552 dbSNP
rs1465175413 560 dbSNP
rs1300728411 570 dbSNP
rs1398305539 573 dbSNP
rs925565935 574 dbSNP
rs546318305 575 dbSNP
rs948299124 581 dbSNP
rs577251434 582 dbSNP
rs1305629799 587 dbSNP
rs1312858652 588 dbSNP
rs1232740292 589 dbSNP
rs117183164 590 dbSNP
rs186396896 591 dbSNP
rs918635835 593 dbSNP
rs142064802 594 dbSNP
rs962820222 600 dbSNP
rs1456822748 607 dbSNP
rs1324538655 615 dbSNP
rs1196060375 620 dbSNP
rs574656066 629 dbSNP
rs781123331 639 dbSNP
rs1487382941 641 dbSNP
rs973756196 645 dbSNP
rs554850349 648 dbSNP
rs955264042 659 dbSNP
rs1330412802 660 dbSNP
rs1397851706 661 dbSNP
rs1326520026 663 dbSNP
rs1368340623 665 dbSNP
rs1218689099 666 dbSNP
rs1299345810 667 dbSNP
rs1016558725 672 dbSNP
rs1219547771 676 dbSNP
rs1257752908 677 dbSNP
rs1316463626 679 dbSNP
rs1005049986 681 dbSNP
rs1355953886 684 dbSNP
rs1029359604 700 dbSNP
rs1247838945 706 dbSNP
rs1488465209 707 dbSNP
rs1010295113 708 dbSNP
rs1263298953 712 dbSNP
rs1477904283 714 dbSNP
rs1169531032 719 dbSNP
rs554923378 725 dbSNP
rs1462842998 736 dbSNP
rs1229405463 737 dbSNP
rs1054580590 743 dbSNP
rs113276393 745 dbSNP
rs1277550274 759 dbSNP
rs549504386 760 dbSNP
rs1045196297 767 dbSNP
rs756812243 768 dbSNP
rs1338850662 777 dbSNP
rs1235495078 779 dbSNP
rs1291105643 780 dbSNP
rs1321631384 781 dbSNP
rs1220094439 794 dbSNP
rs1011562257 808 dbSNP
rs896718075 811 dbSNP
rs539557990 816 dbSNP
rs1260544875 827 dbSNP
rs751072619 828 dbSNP
rs1388192464 832 dbSNP
rs1476011106 833 dbSNP
rs182265455 835 dbSNP
rs929930397 841 dbSNP
rs918679793 845 dbSNP
rs1169255824 849 dbSNP
rs547489814 854 dbSNP
rs1403470124 856 dbSNP
rs527499673 857 dbSNP
rs6580862 858 dbSNP
rs781484080 861 dbSNP
rs548508150 862 dbSNP
rs531627038 867 dbSNP
rs1416921854 868 dbSNP
rs985274075 876 dbSNP
rs1285154746 879 dbSNP
rs562934647 880 dbSNP
rs1378915651 885 dbSNP
rs948478098 893 dbSNP
rs545855537 900 dbSNP
rs1029558037 901 dbSNP
rs988502925 916 dbSNP
rs955858568 919 dbSNP
rs1486445148 921 dbSNP
rs1236625004 927 dbSNP
rs973725034 931 dbSNP
rs1032671418 932 dbSNP
rs888803623 944 dbSNP
rs1380808511 945 dbSNP
rs941042716 955 dbSNP
rs1200262623 956 dbSNP
rs1358776573 957 dbSNP
rs1451090129 963 dbSNP
rs1000380979 964 dbSNP
rs983672711 968 dbSNP
rs577140149 969 dbSNP
rs1023776341 973 dbSNP
rs1378277668 974 dbSNP
rs1240145803 985 dbSNP
rs1012339277 989 dbSNP
rs1306368669 992 dbSNP
rs747161991 993 dbSNP
rs896749124 995 dbSNP
rs1057076678 996 dbSNP
rs1219397171 997 dbSNP
rs1277516792 998 dbSNP
rs1440376820 1001 dbSNP
rs777488533 1002 dbSNP
rs930238359 1004 dbSNP
rs763496089 1016 dbSNP
rs1257189543 1022 dbSNP
rs780152058 1024 dbSNP
rs3803081 1025 dbSNP
rs540287858 1028 dbSNP
rs1378499962 1031 dbSNP
rs1325613970 1035 dbSNP
rs1424693900 1042 dbSNP
rs1283822500 1043 dbSNP
rs750498088 1050 dbSNP
rs1328844881 1052 dbSNP
rs1333782707 1053 dbSNP
rs964813078 1055 dbSNP
rs1330543609 1060 dbSNP
rs1000341502 1063 dbSNP
rs1329938898 1064 dbSNP
rs941467467 1065 dbSNP
rs1332280874 1070 dbSNP
rs1436534972 1071 dbSNP
rs1273783080 1073 dbSNP
rs911287603 1081 dbSNP
rs1017679020 1093 dbSNP
rs1258395659 1102 dbSNP
rs985305213 1105 dbSNP
rs1196631083 1107 dbSNP
rs1391627969 1120 dbSNP
rs538891984 1122 dbSNP
rs1331140259 1124 dbSNP
rs571485903 1135 dbSNP
rs893100461 1141 dbSNP
rs922516652 1154 dbSNP
rs1246268769 1157 dbSNP
rs1031645790 1176 dbSNP
rs1432150076 1177 dbSNP
rs1424725427 1179 dbSNP
rs989168856 1180 dbSNP
rs1169040696 1187 dbSNP
rs955968929 1188 dbSNP
rs1173642451 1189 dbSNP
rs1406520497 1194 dbSNP
rs1477772190 1195 dbSNP
rs998704551 1196 dbSNP
rs1376008793 1199 dbSNP
rs907137778 1200 dbSNP
rs1401402568 1212 dbSNP
rs1183994148 1222 dbSNP
rs1045555038 1231 dbSNP
rs879032181 1232 dbSNP
rs1033114073 1236 dbSNP
rs1339484066 1238 dbSNP
rs978426838 1239 dbSNP
rs1438634931 1242 dbSNP
rs948592292 1253 dbSNP
rs894220914 1259 dbSNP
rs554737790 1284 dbSNP
rs1209169296 1292 dbSNP
rs538189926 1307 dbSNP
rs969792421 1320 dbSNP
rs368072477 1322 dbSNP
rs1449961680 1324 dbSNP
rs1022634010 1338 dbSNP
rs575836417 1339 dbSNP
rs1264132371 1341 dbSNP
rs1477647823 1345 dbSNP
rs190830509 1348 dbSNP
rs185915556 1351 dbSNP
rs1035189630 1354 dbSNP
rs1458809223 1355 dbSNP
rs994858574 1363 dbSNP
rs1387894679 1364 dbSNP
rs146954812 1378 dbSNP
rs1298327258 1384 dbSNP
rs982464042 1386 dbSNP
rs929557403 1388 dbSNP
rs1314525150 1393 dbSNP
rs1340857643 1395 dbSNP
rs1243910924 1406 dbSNP
rs923548900 1415 dbSNP
rs976269998 1417 dbSNP
rs1218859061 1420 dbSNP
rs1286907013 1426 dbSNP
rs1488084544 1426 dbSNP
rs1038797471 1428 dbSNP
rs1239094546 1443 dbSNP
rs965286675 1445 dbSNP
rs759719107 1449 dbSNP
rs17126355 1450 dbSNP
rs1367209014 1452 dbSNP
rs1442146191 1457 dbSNP
rs1158717434 1463 dbSNP
rs1379158747 1465 dbSNP
rs990165216 1468 dbSNP
rs867850834 1476 dbSNP
rs776891962 1477 dbSNP
rs1402594305 1481 dbSNP
rs1395207598 1487 dbSNP
rs1332003712 1497 dbSNP
rs1408738085 1498 dbSNP
rs533825328 1518 dbSNP
rs1052938955 1519 dbSNP
rs934590420 1524 dbSNP
rs907108915 1534 dbSNP
rs1024679714 1535 dbSNP
rs35743935 1540 dbSNP
rs1447453000 1543 dbSNP
rs114508244 1546 dbSNP
rs140139780 1552 dbSNP
rs1483727063 1554 dbSNP
rs969655180 1563 dbSNP
rs894263818 1578 dbSNP
rs6580861 1588 dbSNP
rs1176997191 1593 dbSNP
rs1241753289 1598 dbSNP
rs1459427922 1609 dbSNP
rs992568700 1614 dbSNP
rs1179827707 1615 dbSNP
rs1446283066 1617 dbSNP
rs1379099922 1632 dbSNP
rs959771267 1640 dbSNP
rs1024478083 1647 dbSNP
rs941067411 1655 dbSNP
rs1377822954 1658 dbSNP
rs562660667 1659 dbSNP
rs1465285812 1663 dbSNP
rs1035623902 1664 dbSNP
rs886882597 1675 dbSNP
rs1402203916 1676 dbSNP
rs1041941095 1678 dbSNP
rs1330620133 1682 dbSNP
rs1376206338 1683 dbSNP
rs1389715734 1686 dbSNP
rs1286204608 1695 dbSNP
rs1312989247 1697 dbSNP
rs371865637 1697 dbSNP
rs1232810128 1698 dbSNP
rs1328695175 1701 dbSNP
rs1205261000 1703 dbSNP
rs1046752908 1704 dbSNP
rs933686177 1708 dbSNP
rs1352297240 1713 dbSNP
rs923546055 1717 dbSNP
rs1267521555 1722 dbSNP
rs552412147 1723 dbSNP
rs1432171436 1724 dbSNP
rs181280987 1729 dbSNP
rs994325884 1743 dbSNP
rs773213220 1748 dbSNP
rs768634019 1749 dbSNP
rs1169752958 1751 dbSNP
rs1017153877 1756 dbSNP
rs560066815 1768 dbSNP
rs142238946 1769 dbSNP
rs1459437933 1773 dbSNP
rs889830334 1779 dbSNP
rs1285186122 1784 dbSNP
rs1386377142 1785 dbSNP
rs3759196 1786 dbSNP
rs1342654917 1790 dbSNP
rs910697270 1791 dbSNP
rs779750368 1792 dbSNP
rs990301050 1794 dbSNP
rs1224438721 1796 dbSNP
rs1406159881 1800 dbSNP
rs755913117 1802 dbSNP
rs957437696 1808 dbSNP
rs924732144 1813 dbSNP
rs1420454167 1815 dbSNP
rs901233797 1827 dbSNP
rs1477973655 1829 dbSNP
rs1192657679 1833 dbSNP
rs1417129801 1835 dbSNP
rs977445085 1845 dbSNP
rs1053374408 1850 dbSNP
rs1350500012 1856 dbSNP
rs934475496 1863 dbSNP
rs745598322 1866 dbSNP
rs561182454 1868 dbSNP
rs1301426179 1869 dbSNP
rs117865996 1874 dbSNP
rs1400912562 1876 dbSNP
rs1277892023 1881 dbSNP
rs1360332567 1883 dbSNP
rs958632329 1888 dbSNP
rs188529034 1889 dbSNP
rs1314108450 1890 dbSNP
rs61915222 1892 dbSNP
rs1219598560 1904 dbSNP
rs1005419262 1909 dbSNP
rs1488373239 1914 dbSNP
rs915608445 1926 dbSNP
rs1471677762 1932 dbSNP
rs1484129264 1935 dbSNP
rs992437790 1946 dbSNP
rs1182272607 1976 dbSNP
rs1412949153 1982 dbSNP
rs1442769038 1992 dbSNP
rs1243817680 2002 dbSNP
rs1161745016 2007 dbSNP
rs1382252895 2017 dbSNP
rs1420478822 2022 dbSNP
rs1317936393 2025 dbSNP
rs559005639 2032 dbSNP
rs144072588 2042 dbSNP
rs1283264882 2043 dbSNP
rs1379069967 2049 dbSNP
rs751127672 2055 dbSNP
rs973320909 2057 dbSNP
rs1039388652 2065 dbSNP
rs943600473 2068 dbSNP
rs961530628 2070 dbSNP
rs1017517316 2075 dbSNP
rs1359735802 2076 dbSNP
rs1238920663 2088 dbSNP
rs1313637923 2096 dbSNP
rs1210543775 2100 dbSNP
rs1288671813 2102 dbSNP
rs1459874007 2104 dbSNP
rs1005841183 2108 dbSNP
rs1180446798 2114 dbSNP
rs140083578 2131 dbSNP
rs553801096 2136 dbSNP
rs1440434755 2139 dbSNP
rs4762058 2141 dbSNP
rs184471391 2143 dbSNP
rs924784485 2156 dbSNP
rs1177149833 2169 dbSNP
rs1405821059 2175 dbSNP
rs901260641 2179 dbSNP
rs554676062 2187 dbSNP
rs1401160272 2188 dbSNP
rs1340382983 2189 dbSNP
rs1277322903 2192 dbSNP
rs1439632146 2193 dbSNP
rs999340541 2205 dbSNP
rs1277583151 2210 dbSNP
rs1321184282 2213 dbSNP
rs1200415369 2214 dbSNP
rs1406796208 2230 dbSNP
rs917217023 2231 dbSNP
rs1181163588 2233 dbSNP
rs1236811754 2234 dbSNP
rs1231323844 2245 dbSNP
rs1479094198 2248 dbSNP
rs1350739953 2260 dbSNP
rs991531554 2266 dbSNP
rs1468533990 2268 dbSNP
rs958599639 2271 dbSNP
rs904388049 2273 dbSNP
rs1421377262 2277 dbSNP
rs1016896501 2283 dbSNP
rs1042855698 2292 dbSNP
rs181484822 2297 dbSNP
rs1282279565 2310 dbSNP
rs759042487 2311 dbSNP
rs1343300027 2313 dbSNP
rs1220217968 2314 dbSNP
rs951155721 2334 dbSNP
rs1338668616 2336 dbSNP
rs1025484783 2337 dbSNP
rs1270905458 2338 dbSNP
rs1453428746 2342 dbSNP
rs1222452155 2354 dbSNP
rs1268417770 2356 dbSNP
rs1479611692 2363 dbSNP
rs948664900 2369 dbSNP
rs189432117 2372 dbSNP
rs1475341059 2375 dbSNP
rs552189578 2378 dbSNP
rs1056739187 2379 dbSNP
rs938329339 2380 dbSNP
rs532429986 2381 dbSNP
rs1405415835 2397 dbSNP
rs566565490 2398 dbSNP
rs1218908438 2404 dbSNP
rs1308834857 2406 dbSNP
rs919005455 2413 dbSNP
rs971879725 2414 dbSNP
rs1219592711 2423 dbSNP
rs1278534584 2431 dbSNP
rs1317863971 2436 dbSNP
rs1276836231 2440 dbSNP
rs1225477749 2443 dbSNP
rs889362331 2444 dbSNP
rs1356995303 2453 dbSNP
rs1246732793 2465 dbSNP
rs1054595469 2466 dbSNP
rs1368394564 2475 dbSNP
rs1489919961 2482 dbSNP
rs546576330 2486 dbSNP
rs1293220427 2495 dbSNP
rs936263899 2497 dbSNP
rs149588250 2501 dbSNP
rs903319720 2520 dbSNP
rs1446825972 2527 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucuGACA---CUCGAGGAGCu 5'
             :|||    | ||||||| 
Target 5' guuUUGUCUCCACCUCCUCGc 3'
 		10 - 30
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000313234.5 | 3UTR | UAGGGGUCAGUUUUGUCUCCACCUCCUCGCUCCUCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
25 hsa-miR-151b Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT249674 SLC39A9 solute carrier family 39 member 9 2 4
MIRT366296 GDI1 GDP dissociation inhibitor 1 2 4
MIRT451313 LGALS3BP galectin 3 binding protein 2 2
MIRT467467 SMYD1 SET and MYND domain containing 1 2 4
MIRT477248 ERGIC2 ERGIC and golgi 2 2 2
MIRT489948 RFX2 regulatory factor X2 2 2
MIRT490364 SLC6A1 solute carrier family 6 member 1 2 4
MIRT494531 BCL7A BCL tumor suppressor 7A 2 2
MIRT500190 BARX1 BARX homeobox 1 2 4
MIRT511912 FKBP1A FK506 binding protein 1A 2 2
MIRT524875 ARHGDIA Rho GDP dissociation inhibitor alpha 2 6
MIRT555338 PPP1R3B protein phosphatase 1 regulatory subunit 3B 2 4
MIRT557122 HOXA3 homeobox A3 2 2
MIRT559034 C20orf24 chromosome 20 open reading frame 24 2 4
MIRT559824 SLPI secretory leukocyte peptidase inhibitor 2 2
MIRT568547 AKT2 AKT serine/threonine kinase 2 2 2
MIRT568714 TMEM30B transmembrane protein 30B 2 2
MIRT569827 CRMP1 collapsin response mediator protein 1 2 2
MIRT687618 LYRM4 LYR motif containing 4 2 2
MIRT689949 MANSC1 MANSC domain containing 1 2 2
MIRT690433 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT694845 KRT80 keratin 80 2 2
MIRT697594 YME1L1 YME1 like 1 ATPase 2 2
MIRT697848 UBE2Z ubiquitin conjugating enzyme E2 Z 2 2
MIRT719553 CBLB Cbl proto-oncogene B 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-1 Anthocyanin NULL 145858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Caffeic acid NULL 689043 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Catechin approved 9064 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Ferulic acid NULL 445858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Hesperidin NULL 10621 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Quercetin NULL 5280343 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 up-regulated
miR-1 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Quantitative real-time PCR myocardial differentiation of mouse ES cells 19521018 2009 down-regulated
miR-1 Sulfonyl-hydrazone-1 (SHZ) NULL NULL Quantitative real-time PCR Murine broblast-derived Induced pluripotent stem cells 21445862 2011 up-regulated
miR-1 Cocaine NULL 446220 Next-generation sequencing ventral striatum 21708909 2011 up-regulated
miR-1 Atorvastatin approved 60823 Quantitative real-time PCR Cardiomyocyte 23860036 2013 down-regualted
miR-1 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-1 Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 Palmitic acid approved 985 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miR-1 Essential amino acids (EAA) NULL NULL Quantitative real-time PCR skeletal muscle of young adults 19828686 2009 up-regulated
miR-1 Hydrogen peroxide (H2O2) NULL 784 Quantitative real-time PCR Human umbilical vein endothelial cells 21527937 2011 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Microarray apoptosis-resistant breast cancer cells 21971930 2011 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-1 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-1 Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR cardia 22889704 2012 up-regulated
miR-1 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-1 Quinidine approved 441074 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 up-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 down-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR post-infarction rat cardiomyocytes 21220930 2011 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miR-1 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-151b Platinum 23939 resistant High Ovarian Cancer tissue
hsa-miR-151b Paclitaxel 36314 NSC125973 approved sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-151b Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (M14) (50nM)
hsa-miR-151b Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (M14) (50nM)
hsa-miR-151b Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (WM266) (2uM)
hsa-miR-151b Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (WM266) (2uM)
hsa-miR-151b Ruxolitinib 25126798 NSC763371 approved sensitive Low Myelofibrosis tissue
hsa-mir-151b Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-151b Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-mir-151b Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-151b Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (cytosolic RNA)
hsa-miR-151b Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-151b Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-151b Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-151b Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-151b Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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