miRTarBase - #MIRT696368


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pre-miRNA Information
pre-miRNA hsa-mir-4419b   
Genomic Coordinates chr12: 128244506 - 128244573
Description Homo sapiens miR-4419b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4419b
Sequence 42| GAGGCUGAAGGAAGAUGG |59
Evidence Experimental
Experiments Illumina
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol EIF2S3   
Synonyms EIF2, EIF2G, EIF2gamma, MRXSBRK, eIF-2gA
Description eukaryotic translation initiation factor 2 subunit gamma
Transcript NM_001415   
Expression
Putative miRNA Targets on EIF2S3
3'UTR of EIF2S3
(miRNA target sites are highlighted)		 
>EIF2S3|NM_001415|3'UTR
   1 AGAATACCAGTTAAATAATACATTCGGATGGATTTGGAAGTTGGAATTCCTCTTAACAACCAAGGGGTTTATTTTCAAAG
  81 CAATATTGGGGAATTGATTTCACAGTTCGTTACCTTAGTAGGTAACGGTAAGGTTATTCTCTTTTTTTTTTTTTTTTTTT
 161 TTGGTTATGAAAACTTAGGGACTAAAATTAATATAAAAATTGGCATAATGTTGGATTGAATCTACATTTTGGCAGAAGTT
 241 AAACATTCCCACATAATGTCAAAATTATACATCATGCAGTTCTGTTTTTTTGTTTGTTTTATTTTGTTTTGTTTTTGAGT
 321 CTGGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTGCAACCTCTGCCCCCCGGGTTCAAGCGATTCTCCTGCCTC
 401 AGCCTCCCGAGTAGCTGAGATTACAGGTGCGCGCCACCACACTTGGCTAATTTTTGTATTATTAGTAGAGACGGGGTTTC
 481 AGCATGTTGGCTAGGCCGGTCTCTCCTGACCTCAGGGTGATCAGCCCACCTCGGCCTCACAAAGTGCTGGGATTACAGGC
 561 GTGAGCCACCTTGCCCAGCCCACATCATACAGTTTGAAATGAAACTTTGCCACAACCAGCCTTTGCTGTAGCACACACAT
 641 ATATCACTGAACCTGTTTGAAATAAAGTTTTTTTTCTTTTTCATGATTCGTCTTTGAGTACCTCCAGGCTGAAAGACTGT
 721 TGTACCAGTAAAAACTTAAAGGCACAAATTCTCCTTGAAGACCTTCTCCCTTTTATGTGGCCCCATATTTTATGTTGCTT
 801 TATCTTTGAAATTTTGCATGAAAAGGAAATGAATGGATTCGAATGAAATTGTCCTTTAGAGCATGATTACTTGTTCCCAT
 881 GGACAAATATTTTTCTCCCCTTGCTCTTCCTGGCCTGAAACACGGGAAACCAGAGTCAAAAGTTATCTCCCTCTCCCTGT
 961 GATGCCTTGAGATTTTTTTCTGCGTTGTTTAATGCCTGAAATCCAAGTCTTCCTCCATGGGAAAATACTGTTATACCAAA
1041 TAATTCTAGATGAGTAACAAAGATCTTTTTAGGCCTTCATTTTATGTTTTTTCTTAACTGTTATATTATGATTGTGACAT
1121 AGATTATACTACTACTAATTTTTGGATGTTTCAAAAGGTCAAGAAGTAAAAGATGTTAGAAAGCAATGAGTGAGTCCTTT
1201 TGATTTTTAACTTATTCCCCATGTCCCTATACTTCGTGTGCTTTTCCTTTTTTTTTTTGAGACGGAGGCTCACTCCGTCA
1281 CCTAGGCTAGAGTACAGTGGCACGATCTTGGCTCGCTGCAACCTCTGCCTCCCTGATTCAAGTGATTCTCGTGCTTCAGC
1361 CTCCCATGTAGCTGATATTACAGGCACTTGCCACCATACCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACC
1441 ATGTTGCCCAGGCTGGTCTTGAACTCCTAACCTCAGGTGATCCGCCCGCCTCTGCCTTCCAAAGTGCTGGGATTACAGGC
1521 GTGAGCCACTCTGCCCGGCTTATTTTTCTTTATGTTTTTGCTTCGTAAGAGGTTCTGTTGAGCAGTGATTTGCAACTCTT
1601 GCTGACGTTGCTGGGGAAGCTTTAAAAAAAAAAAAGATGCCCCACAGAGATTCTGATTTTAATTGTTCTGATTTAATTGG
1681 CTTGGAGTAGAATTCAGGCATTGATATCTTTAAAAACTCCCCAGTGTTGAGAAACAAATTTAGAGAGTTGAGAAGTAGGT
1761 ATATTAAATTACAGAATCTTACTGAGTTTTGGTAGACTGATAATACAATTTGCTTTGCTTTTCTTAAATTTGCATTGAGA
1841 TGGGATTTGAAGCATATTGTGCTCTTGTGAATGTTGAAGTTGCATTGTAGAAGTTTAGAAGCTCTGGCTATGGGTTGCCT
1921 AAATTGATGTTTTGAGGAAGCATATTAATGTTATAAACTTCGCTGACTTTGAAGGTTGTGTTGTAGCATGAGGAACACAA
2001 ATAAAACAATTCTAAATCAAACTAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gguAGAAGGAAGUCGGAg 5'
             || | ||||||||| 
Target 5' ttcTCGTGCTTCAGCCTc 3'
 1346 - 1363 159.00 -18.00
2 
miRNA  3' ggUAGAAGGA---AGUCGGAg 5'
            ||: ||||   ||||||| 
Target 5' cgATTCTCCTGCCTCAGCCTc 3'
 386 - 406 156.00 -17.50
3 
miRNA  3' ggUAGAAG---GAAGUCGGAg 5'
            |||  |   | ||:|||| 
Target 5' tgATCAGCCCACCTCGGCCTc 3'
 518 - 538 128.00 -15.90
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs773796835 7 dbSNP
rs749718018 14 dbSNP
rs1246106249 23 dbSNP
rs1466144042 24 dbSNP
rs1284964911 25 dbSNP
rs369749610 26 dbSNP
rs1242265121 27 dbSNP
rs771163509 37 dbSNP
rs776241535 43 dbSNP
rs1368600750 53 dbSNP
rs761773962 59 dbSNP
rs1332120579 61 dbSNP
rs111630683 84 dbSNP
rs1469285068 85 dbSNP
rs1389178273 86 dbSNP
rs1012096463 87 dbSNP
rs111372663 109 dbSNP
rs1236761845 127 dbSNP
rs1419609574 128 dbSNP
rs191563492 134 dbSNP
rs1182097205 137 dbSNP
rs199708557 138 dbSNP
rs372625244 139 dbSNP
rs762440475 139 dbSNP
rs1209395867 140 dbSNP
rs1230580744 140 dbSNP
rs1271987474 140 dbSNP
rs1290879026 140 dbSNP
rs1293619037 140 dbSNP
rs1323808715 140 dbSNP
rs1351341333 140 dbSNP
rs1354416948 140 dbSNP
rs1365797552 140 dbSNP
rs1401264495 140 dbSNP
rs1432657141 140 dbSNP
rs747088489 140 dbSNP
rs376888206 141 dbSNP
rs1167335026 142 dbSNP
rs1225992450 142 dbSNP
rs1275201860 142 dbSNP
rs1309420361 142 dbSNP
rs1329029211 142 dbSNP
rs1369329118 142 dbSNP
rs1369543346 142 dbSNP
rs1388015465 142 dbSNP
rs1416643297 142 dbSNP
rs1429845927 142 dbSNP
rs1435366723 142 dbSNP
rs5949273 142 dbSNP
rs879230822 142 dbSNP
rs1426372221 144 dbSNP
rs1190945241 145 dbSNP
rs1166426545 161 dbSNP
rs1234835856 163 dbSNP
rs1477220455 163 dbSNP
rs754534322 163 dbSNP
rs1394516373 164 dbSNP
rs1386262070 165 dbSNP
rs5949274 166 dbSNP
rs900330663 168 dbSNP
rs1329141651 169 dbSNP
rs1375273518 170 dbSNP
rs764546995 171 dbSNP
rs1391750919 175 dbSNP
rs1313855138 176 dbSNP
rs1279198665 180 dbSNP
rs1218454786 199 dbSNP
rs1342546504 203 dbSNP
rs747020844 206 dbSNP
rs1340066979 216 dbSNP
rs1349400994 233 dbSNP
rs1305619807 248 dbSNP
rs1450862926 254 dbSNP
rs755285963 269 dbSNP
rs1360280324 283 dbSNP
rs1175914194 286 dbSNP
rs1413132709 287 dbSNP
rs754187586 289 dbSNP
rs1231579216 293 dbSNP
rs1295222170 297 dbSNP
rs905941576 297 dbSNP
rs146275076 301 dbSNP
rs779548178 312 dbSNP
rs1409905249 313 dbSNP
rs1198572182 325 dbSNP
rs1003391589 332 dbSNP
rs1238001289 335 dbSNP
rs1250064959 354 dbSNP
rs1209257363 355 dbSNP
rs746010027 365 dbSNP
rs1196739600 371 dbSNP
rs1255092947 375 dbSNP
rs183853883 377 dbSNP
rs112482955 378 dbSNP
rs1379186500 384 dbSNP
rs796118641 387 dbSNP
rs111579157 388 dbSNP
rs1477176898 409 dbSNP
rs1457011812 410 dbSNP
rs1410068194 420 dbSNP
rs3207873 424 dbSNP
rs781513490 431 dbSNP
rs748355601 432 dbSNP
rs1356206711 433 dbSNP
rs1462346340 434 dbSNP
rs1016472778 457 dbSNP
rs1249706276 457 dbSNP
rs769666674 473 dbSNP
rs747279131 474 dbSNP
rs1265863628 477 dbSNP
rs1223225739 482 dbSNP
rs375249551 486 dbSNP
rs1311367463 498 dbSNP
rs1227153109 499 dbSNP
rs1413197882 518 dbSNP
rs1368016672 529 dbSNP
rs1295278157 531 dbSNP
rs974879790 533 dbSNP
rs1434849534 534 dbSNP
rs922129214 540 dbSNP
rs1295578573 549 dbSNP
rs1458592680 553 dbSNP
rs1349423621 561 dbSNP
rs768724793 566 dbSNP
rs772875198 570 dbSNP
rs954473303 576 dbSNP
rs1391970843 584 dbSNP
rs749304872 585 dbSNP
rs1228674533 591 dbSNP
rs923608421 593 dbSNP
rs3207877 613 dbSNP
rs1259389405 614 dbSNP
rs934996622 626 dbSNP
rs1255804151 627 dbSNP
rs1264389796 635 dbSNP
rs1053671498 636 dbSNP
rs1484857345 642 dbSNP
rs1343610520 644 dbSNP
rs1275986323 653 dbSNP
rs570029856 660 dbSNP
rs1363538680 668 dbSNP
rs1303832306 671 dbSNP
rs114095209 677 dbSNP
rs1367210277 691 dbSNP
rs947988877 698 dbSNP
rs1291952281 705 dbSNP
rs1257766181 710 dbSNP
rs1487716246 711 dbSNP
rs1044901008 716 dbSNP
rs1184227680 726 dbSNP
rs1169217032 739 dbSNP
rs1421632011 754 dbSNP
rs1429066938 763 dbSNP
rs1177927385 765 dbSNP
rs1433508297 766 dbSNP
rs34373297 771 dbSNP
rs17217346 781 dbSNP
rs1196757951 793 dbSNP
rs906386831 804 dbSNP
rs773914313 808 dbSNP
rs1436286197 812 dbSNP
rs73626807 826 dbSNP
rs1337983273 837 dbSNP
rs1376285359 842 dbSNP
rs1234445068 843 dbSNP
rs1311915055 861 dbSNP
rs1281617929 862 dbSNP
rs1411892847 864 dbSNP
rs1351241922 876 dbSNP
rs1307470397 879 dbSNP
rs1399519715 890 dbSNP
rs773100426 891 dbSNP
rs1287168103 898 dbSNP
rs369824654 901 dbSNP
rs1364123042 910 dbSNP
rs1409174902 924 dbSNP
rs111365706 925 dbSNP
rs1002930205 934 dbSNP
rs373279652 936 dbSNP
rs1466367632 942 dbSNP
rs1346240824 943 dbSNP
rs1376855977 950 dbSNP
rs1057466974 951 dbSNP
rs1473356631 952 dbSNP
rs886403120 955 dbSNP
rs5990022 958 dbSNP
rs1280651947 961 dbSNP
rs1258888671 973 dbSNP
rs1342519226 984 dbSNP
rs1201458520 985 dbSNP
rs1483166346 985 dbSNP
rs1261645682 995 dbSNP
rs1230513328 1004 dbSNP
rs1004847506 1008 dbSNP
rs1287917658 1015 dbSNP
rs1352506294 1035 dbSNP
rs1342276151 1041 dbSNP
rs1314852841 1043 dbSNP
rs1396526484 1066 dbSNP
rs759230168 1066 dbSNP
rs1401294331 1075 dbSNP
rs767019726 1099 dbSNP
rs554809635 1101 dbSNP
rs1388950085 1104 dbSNP
rs775164804 1105 dbSNP
rs1213156622 1106 dbSNP
rs1468158474 1112 dbSNP
rs1369688654 1115 dbSNP
rs1188921069 1119 dbSNP
rs1016259343 1120 dbSNP
rs1243373088 1122 dbSNP
rs1241722441 1124 dbSNP
rs899406195 1127 dbSNP
rs1211002940 1131 dbSNP
rs1465588019 1134 dbSNP
rs1485867854 1138 dbSNP
rs1203614025 1146 dbSNP
rs754310279 1161 dbSNP
rs760316459 1169 dbSNP
rs996413792 1174 dbSNP
rs1251042981 1187 dbSNP
rs1029089110 1203 dbSNP
rs757690866 1207 dbSNP
rs1395971817 1212 dbSNP
rs73626808 1219 dbSNP
rs1365567969 1221 dbSNP
rs765692976 1230 dbSNP
rs1317279861 1232 dbSNP
rs1398579534 1233 dbSNP
rs750946562 1235 dbSNP
rs1392316981 1236 dbSNP
rs1163297275 1239 dbSNP
rs1190994172 1248 dbSNP
rs748940396 1248 dbSNP
rs955065747 1248 dbSNP
rs1347053215 1249 dbSNP
rs1191368812 1253 dbSNP
rs1431556918 1260 dbSNP
rs1290813907 1265 dbSNP
rs1209343348 1266 dbSNP
rs548443882 1272 dbSNP
rs1289507418 1274 dbSNP
rs547123775 1277 dbSNP
rs755245748 1278 dbSNP
rs1269356001 1289 dbSNP
rs1428258331 1291 dbSNP
rs750699468 1295 dbSNP
rs1332488934 1304 dbSNP
rs1323749509 1315 dbSNP
rs758953483 1316 dbSNP
rs5949219 1319 dbSNP
rs1143263 1324 dbSNP
rs1389994331 1330 dbSNP
rs989141936 1339 dbSNP
rs1479182441 1340 dbSNP
rs751714842 1354 dbSNP
rs914932158 1365 dbSNP
rs1489898757 1367 dbSNP
rs947937933 1368 dbSNP
rs1207268769 1376 dbSNP
rs980694694 1382 dbSNP
rs1317045842 1384 dbSNP
rs748006785 1386 dbSNP
rs1271237824 1387 dbSNP
rs927794624 1392 dbSNP
rs1469746644 1398 dbSNP
rs1194130070 1402 dbSNP
rs769550938 1403 dbSNP
rs939183367 1409 dbSNP
rs1222511082 1411 dbSNP
rs772939344 1422 dbSNP
rs368898207 1423 dbSNP
rs1354490660 1434 dbSNP
rs1327372623 1438 dbSNP
rs770703518 1439 dbSNP
rs1175763122 1442 dbSNP
rs940802458 1448 dbSNP
rs1410435050 1457 dbSNP
rs1037654609 1464 dbSNP
rs1164278160 1468 dbSNP
rs1414332623 1468 dbSNP
rs1183020463 1472 dbSNP
rs1392320983 1476 dbSNP
rs1463506923 1484 dbSNP
rs1223435424 1485 dbSNP
rs899185377 1488 dbSNP
rs1327082062 1489 dbSNP
rs773924394 1505 dbSNP
rs996362954 1510 dbSNP
rs1029663579 1518 dbSNP
rs890597491 1521 dbSNP
rs1440450048 1522 dbSNP
rs1202687405 1529 dbSNP
rs758955981 1543 dbSNP
rs184593345 1544 dbSNP
rs1321015647 1545 dbSNP
rs1373567071 1551 dbSNP
rs1228486289 1565 dbSNP
rs539509978 1566 dbSNP
rs775251721 1568 dbSNP
rs1031207075 1572 dbSNP
rs956639049 1572 dbSNP
rs1360157107 1576 dbSNP
rs1336241454 1592 dbSNP
rs762318972 1601 dbSNP
rs1468528733 1603 dbSNP
rs1226042067 1606 dbSNP
rs1214260302 1607 dbSNP
rs1257331424 1608 dbSNP
rs373127191 1617 dbSNP
rs1175463356 1624 dbSNP
rs1266765067 1624 dbSNP
rs1405875681 1624 dbSNP
rs989256175 1625 dbSNP
rs1202821171 1635 dbSNP
rs1459768879 1636 dbSNP
rs1269633658 1652 dbSNP
rs1208962648 1666 dbSNP
rs1315871108 1673 dbSNP
rs1281496105 1691 dbSNP
rs755153516 1698 dbSNP
rs1234865939 1705 dbSNP
rs1450926876 1712 dbSNP
rs1470649304 1715 dbSNP
rs1321544854 1726 dbSNP
rs1453297974 1732 dbSNP
rs969060745 1746 dbSNP
rs1167043643 1748 dbSNP
rs1415780465 1751 dbSNP
rs1385806067 1762 dbSNP
rs1182844554 1776 dbSNP
rs980643723 1777 dbSNP
rs1476192130 1781 dbSNP
rs927878640 1783 dbSNP
rs1485321144 1808 dbSNP
rs1239960571 1809 dbSNP
rs939316474 1814 dbSNP
rs140754709 1815 dbSNP
rs1396399033 1818 dbSNP
rs1408611550 1823 dbSNP
rs1244416398 1833 dbSNP
rs1331263873 1860 dbSNP
rs908400426 1865 dbSNP
rs1381972121 1868 dbSNP
rs1360162580 1873 dbSNP
rs34323788 1884 dbSNP
rs1355429284 1885 dbSNP
rs1437291429 1901 dbSNP
rs1365035593 1906 dbSNP
rs940751588 1911 dbSNP
rs190407199 1920 dbSNP
rs763524866 1921 dbSNP
rs1170915806 1941 dbSNP
rs931993635 1955 dbSNP
rs1233360434 1962 dbSNP
rs1192501864 1963 dbSNP
rs781385103 1968 dbSNP
rs1490389384 1987 dbSNP
rs1129148 1998 dbSNP
rs1267538844 2003 dbSNP
rs1337346361 2003 dbSNP
rs1216210176 2013 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gguagaAGGAAGUCGGAg 5'
                |:|| | |||| 
Target 5' aagcgaUUCUCCUGCCUc 3'
 		20 - 37
2 
miRNA  3' gguagaagGAAGUCGGag 5'
                  | || |||  
Target 5' -------aCCUCUGCCcc 3'
 		1 - 11
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_001415 | 3UTR | CACCCAGGCUGGAGUGCAGUGGCGUGAUCUGCAACCUCUGCCCCCCGGGUUCAAGCGAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGAGAUUACAGGUGCGCGCCACCACACUUGGCUAAUUUUUGUAUUAUUAGUAGAGACGGGGUUUCAGCAUGUUGGCUAGGCCGGUCUCUCCUGACCUCAGGGUGAUCAGCCCACCUCGGCCUCACAAAGUGCUGGGAUUACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_001415 | 3UTR | CCAGGCUGGAGUGCAGUGGCGUGAUCUGCAACCUCUGCCCCCCGGGUUCAAGCGAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGAGAUUACAGGUGCGCGCCACCACACUUGGCUAAUUUUUGUAUUAUUAGUAGAGACGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_001415 | 3UTR | CACCCAGGCUGGAGUGCAGUGGCGUGAUCUGCAACCUCUGCCCCCCGGGUUCAAGCGAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGAGAUUACAGGUGCGCGCCACCACACUUGGCUAAUUUUUGUAUUAUUAGUAGAGACGGGGUUUCAGCAUGUUGGCUAGGCCGGUCUCUCCUGACCUCAGGGUGAUCAGCCCACCUCGGCCUCACAAAGUGCUGGGAUUACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_001415 | 3UTR | UCUGGCUCUGUCACCCAGGCUGGAGUGCAGUGGCGUGAUCUGCAACCUCUGCCCCCCGGGUUCAAGCGAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGAGAUUACAGGUGCGCGCCACCACACUUGGCUAAUUUUUGUAUUAUUAGUAGAGACGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_001415 | 3UTR | ACCCAGGCUGGAGUGCAGUGGCGUGAUCUGCAACCUCUGCCCCCCGGGUUCAAGCGAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGAGAUUACAGGUGCGCGCCACCACACUUGGCUAAUUUUUGUAUUAUUAGUAGAGACGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_001415 | 3UTR | ACCCAGGCUGGAGUGCAGUGGCGUGAUCUGCAACCUCUGCCCCCCGGGUUCAAGCGAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGAGAUUACAGGUGCGCGCCACCACACUUGGCUAAUUUUUGUAUUAUUAGUAGAGACGGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000253039.4 | 3UTR | ACCUCUGCCCCCCGGGUUCAAGCGAUUCUCCUGCCUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
390 hsa-miR-4419b Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061343 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT072743 GLCE glucuronic acid epimerase 2 2
MIRT180549 TXNIP thioredoxin interacting protein 2 2
MIRT186147 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT271044 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 4
MIRT334761 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 6
MIRT443279 TSPAN15 tetraspanin 15 2 2
MIRT447047 ZNF439 zinc finger protein 439 2 2
MIRT447351 KIF6 kinesin family member 6 2 2
MIRT448925 CKS1B CDC28 protein kinase regulatory subunit 1B 2 2
MIRT452899 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT453087 SUMF2 sulfatase modifying factor 2 2 2
MIRT454071 SLC35E3 solute carrier family 35 member E3 2 2
MIRT456216 LIX1L limb and CNS expressed 1 like 2 6
MIRT456951 LRP10 LDL receptor related protein 10 2 2
MIRT458025 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT459999 RFT1 RFT1 homolog 2 2
MIRT460046 CDCP1 CUB domain containing protein 1 2 2
MIRT460982 STK17B serine/threonine kinase 17b 2 2
MIRT464405 URM1 ubiquitin related modifier 1 2 2
MIRT466256 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 2
MIRT466536 TBXA2R thromboxane A2 receptor 2 2
MIRT470922 PLD5 phospholipase D family member 5 2 8
MIRT472835 MTMR10 myotubularin related protein 10 2 6
MIRT473352 MEMO1 mediator of cell motility 1 2 2
MIRT475504 HSP90B1 heat shock protein 90 beta family member 1 2 2
MIRT478862 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT480898 BCL9L B-cell CLL/lymphoma 9 like 2 2
MIRT482686 NXN nucleoredoxin 2 4
MIRT484128 C14orf142 GON7, KEOPS complex subunit homolog 2 2
MIRT486172 TLE3 transducin like enhancer of split 3 2 4
MIRT486539 CLCN7 chloride voltage-gated channel 7 2 2
MIRT486588 ZNF619 zinc finger protein 619 2 2
MIRT495475 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT495536 TXNRD2 thioredoxin reductase 2 2 2
MIRT495566 UNC5C unc-5 netrin receptor C 2 2
MIRT495719 PADI1 peptidyl arginine deiminase 1 2 2
MIRT495890 CLOCK clock circadian regulator 2 2
MIRT495932 SLC7A5P2 solute carrier family 7 member 5 pseudogene 2 2 2
MIRT496026 ZBED3 zinc finger BED-type containing 3 2 2
MIRT496216 PAX6 paired box 6 2 2
MIRT496349 VAMP1 vesicle associated membrane protein 1 2 2
MIRT496354 PPY pancreatic polypeptide 2 2
MIRT496400 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT496416 PARVB parvin beta 2 2
MIRT496458 N6AMT1 N-6 adenine-specific DNA methyltransferase 1 2 2
MIRT496519 GINS2 GINS complex subunit 2 2 2
MIRT496562 SLC39A9 solute carrier family 39 member 9 2 2
MIRT498605 KRT8 keratin 8 2 2
MIRT503434 SLC25A45 solute carrier family 25 member 45 2 6
MIRT503573 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 2
MIRT503847 ATP13A4 ATPase 13A4 2 4
MIRT504247 LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2 4
MIRT505606 SLC35F1 solute carrier family 35 member F1 2 2
MIRT507749 CERS2 ceramide synthase 2 2 4
MIRT508411 C1orf210 chromosome 1 open reading frame 210 2 6
MIRT508508 RSRC1 arginine and serine rich coiled-coil 1 2 6
MIRT508944 AK4 adenylate kinase 4 2 4
MIRT509460 ZNF587 zinc finger protein 587 2 6
MIRT509862 ZNF641 zinc finger protein 641 2 4
MIRT511397 IKZF3 IKAROS family zinc finger 3 2 6
MIRT512517 BTBD19 BTB domain containing 19 2 2
MIRT513507 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 6
MIRT514155 TMEM145 transmembrane protein 145 2 4
MIRT514486 SLPI secretory leukocyte peptidase inhibitor 2 4
MIRT514521 SHISA9 shisa family member 9 2 2
MIRT514970 KLLN killin, p53-regulated DNA replication inhibitor 2 4
MIRT515030 IRAK4 interleukin 1 receptor associated kinase 4 2 6
MIRT515963 C9orf156 tRNA methyltransferase O 2 2
MIRT516092 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 2 4
MIRT517223 PRIM1 DNA primase subunit 1 2 4
MIRT517459 PEX26 peroxisomal biogenesis factor 26 2 4
MIRT517790 EFCAB11 EF-hand calcium binding domain 11 2 2
MIRT517979 DSCR3 DSCR3 arrestin fold containing 2 2
MIRT519458 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT519599 ZNF805 zinc finger protein 805 2 2
MIRT520339 UBXN2A UBX domain protein 2A 2 2
MIRT521345 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT521571 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT523382 GSG2 histone H3 associated protein kinase 2 8
MIRT524106 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT524886 ARHGAP11A Rho GTPase activating protein 11A 2 4
MIRT528772 CD1D CD1d molecule 2 2
MIRT530665 TRIM56 tripartite motif containing 56 2 2
MIRT531107 PEX13 peroxisomal biogenesis factor 13 2 2
MIRT531575 ILDR1 immunoglobulin like domain containing receptor 1 2 2
MIRT535173 PLEKHB2 pleckstrin homology domain containing B2 2 4
MIRT544168 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT550582 SLC2A5 solute carrier family 2 member 5 2 2
MIRT551039 GDE1 glycerophosphodiester phosphodiesterase 1 2 4
MIRT551295 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT551339 MRE11A MRE11 homolog, double strand break repair nuclease 2 2
MIRT552092 SLFN12L schlafen family member 12 like 2 6
MIRT555403 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT557087 HOXB3 homeobox B3 2 2
MIRT559388 ATP11C ATPase phospholipid transporting 11C 2 2
MIRT560305 DFFA DNA fragmentation factor subunit alpha 2 2
MIRT561028 LIN7C lin-7 homolog C, crumbs cell polarity complex component 2 2
MIRT562460 COX6B1 cytochrome c oxidase subunit 6B1 2 4
MIRT562982 PARK7 Parkinsonism associated deglycase 2 2
MIRT563548 PMPCA peptidase, mitochondrial processing alpha subunit 2 2
MIRT564412 EMILIN2 elastin microfibril interfacer 2 2 4
MIRT569437 PCGF3 polycomb group ring finger 3 2 2
MIRT572097 EXOC8 exocyst complex component 8 2 2
MIRT575571 Cd99 CD99 antigen 2 2
MIRT575789 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 2 2
MIRT576975 Lmtk2 lemur tyrosine kinase 2 2 2
MIRT610864 ARSA arylsulfatase A 2 2
MIRT614061 NTPCR nucleoside-triphosphatase, cancer-related 2 2
MIRT614141 THAP1 THAP domain containing 1 2 6
MIRT615235 BROX BRO1 domain and CAAX motif containing 2 2
MIRT617429 ANP32E acidic nuclear phosphoprotein 32 family member E 2 4
MIRT618882 MBL2 mannose binding lectin 2 2 2
MIRT618984 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT619196 SLC16A4 solute carrier family 16 member 4 2 2
MIRT620323 AQP6 aquaporin 6 2 2
MIRT621960 STX7 syntaxin 7 2 2
MIRT622057 SSBP2 single stranded DNA binding protein 2 2 2
MIRT624930 FBXW2 F-box and WD repeat domain containing 2 2 2
MIRT624986 ZNF665 zinc finger protein 665 2 4
MIRT625463 ZNF681 zinc finger protein 681 2 4
MIRT625497 SMAD9 SMAD family member 9 2 2
MIRT625599 KLHL23 kelch like family member 23 2 2
MIRT625668 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT625888 INADL PATJ, crumbs cell polarity complex component 2 2
MIRT626161 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT626238 ZNF749 zinc finger protein 749 2 2
MIRT626631 SLC30A6 solute carrier family 30 member 6 2 2
MIRT626994 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT627898 OLFML2A olfactomedin like 2A 2 2
MIRT627988 NDRG3 NDRG family member 3 2 2
MIRT628324 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT628549 ZNF701 zinc finger protein 701 2 2
MIRT629464 WIZ widely interspaced zinc finger motifs 2 2
MIRT630527 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT631487 KLHL21 kelch like family member 21 2 2
MIRT631957 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 4
MIRT632178 CCL22 C-C motif chemokine ligand 22 2 2
MIRT632282 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT632321 TMEM185B transmembrane protein 185B 2 2
MIRT632853 IGF1 insulin like growth factor 1 2 2
MIRT632862 HSPA2 heat shock protein family A (Hsp70) member 2 2 2
MIRT633322 LINC00346 long intergenic non-protein coding RNA 346 2 2
MIRT633398 FBXW8 F-box and WD repeat domain containing 8 2 2
MIRT633930 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT634785 CBFA2T2 CBFA2/RUNX1 translocation partner 2 2 2
MIRT634851 ABCF1 ATP binding cassette subfamily F member 1 2 2
MIRT636370 OGFRL1 opioid growth factor receptor like 1 2 2
MIRT637219 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT637690 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D 2 2
MIRT639196 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT639599 CD3EAP CD3e molecule associated protein 2 2
MIRT639681 PPEF2 protein phosphatase with EF-hand domain 2 2 4
MIRT640669 ARSK arylsulfatase family member K 2 2
MIRT642377 ZNF581 zinc finger protein 581 2 2
MIRT642403 ZNF556 zinc finger protein 556 2 2
MIRT645079 UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII 2 2
MIRT646475 ZNF669 zinc finger protein 669 2 2
MIRT647325 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT647490 ZNF639 zinc finger protein 639 2 2
MIRT647989 PDE12 phosphodiesterase 12 2 2
MIRT648196 CENPN centromere protein N 2 2
MIRT649006 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT650457 ZNF141 zinc finger protein 141 2 2
MIRT650533 CCDC77 coiled-coil domain containing 77 2 2
MIRT650999 ZNF770 zinc finger protein 770 2 2
MIRT653832 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 4
MIRT655734 NRXN3 neurexin 3 2 2
MIRT657577 GRSF1 G-rich RNA sequence binding factor 1 2 2
MIRT658610 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 2
MIRT658633 ENAH ENAH, actin regulator 2 2
MIRT659820 CASP16 caspase 16, pseudogene 2 2
MIRT661142 ZNF43 zinc finger protein 43 2 2
MIRT661201 MPPE1 metallophosphoesterase 1 2 2
MIRT661436 MANSC1 MANSC domain containing 1 2 2
MIRT661498 CHMP1B charged multivesicular body protein 1B 2 2
MIRT661682 ZNF623 zinc finger protein 623 2 2
MIRT661796 NLRC3 NLR family CARD domain containing 3 2 2
MIRT661808 NUP85 nucleoporin 85 2 2
MIRT661861 ZNF766 zinc finger protein 766 2 2
MIRT661889 EXOSC6 exosome component 6 2 2
MIRT662291 SLC29A4 solute carrier family 29 member 4 2 2
MIRT662515 ANGPT4 angiopoietin 4 2 2
MIRT662682 LRRC47 leucine rich repeat containing 47 2 2
MIRT662716 C10orf111 chromosome 10 open reading frame 111 2 4
MIRT662834 LY6G5B lymphocyte antigen 6 family member G5B 2 2
MIRT662890 PCDHA6 protocadherin alpha 6 2 2
MIRT663134 ULBP3 UL16 binding protein 3 2 2
MIRT663710 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663869 MUC20 mucin 20, cell surface associated 2 2
MIRT664267 NMUR1 neuromedin U receptor 1 2 2
MIRT664510 POLR3K RNA polymerase III subunit K 2 2
MIRT664659 TRIM65 tripartite motif containing 65 2 2
MIRT664849 HUS1 HUS1 checkpoint clamp component 2 2
MIRT664944 CARD6 caspase recruitment domain family member 6 2 4
MIRT665348 YES1 YES proto-oncogene 1, Src family tyrosine kinase 2 2
MIRT665514 UTP15 UTP15, small subunit processome component 2 2
MIRT665648 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT665668 TRAF1 TNF receptor associated factor 1 2 2
MIRT665692 TNPO3 transportin 3 2 2
MIRT665741 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT665850 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT665940 TBC1D19 TBC1 domain family member 19 2 4
MIRT666005 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT666172 SNX27 sorting nexin family member 27 2 4
MIRT666373 SHOX short stature homeobox 2 2
MIRT667004 PDPN podoplanin 2 4
MIRT667185 NR2F6 nuclear receptor subfamily 2 group F member 6 2 4
MIRT667603 LIPC lipase C, hepatic type 2 2
MIRT667828 IRGQ immunity related GTPase Q 2 2
MIRT667862 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT668296 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 4
MIRT668463 FAM208A family with sequence similarity 208 member A 2 2
MIRT668580 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 4
MIRT669012 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT669103 CDK19 cyclin dependent kinase 19 2 2
MIRT670073 ZNF783 zinc finger family member 783 2 2
MIRT670326 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT670756 HOOK3 hook microtubule tethering protein 3 2 2
MIRT670964 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT670985 MED17 mediator complex subunit 17 2 2
MIRT671195 ZNF891 zinc finger protein 891 2 2
MIRT672423 SLC10A6 solute carrier family 10 member 6 2 2
MIRT672495 YIPF4 Yip1 domain family member 4 2 2
MIRT672537 MGAM maltase-glucoamylase 2 2
MIRT672749 ZNF585B zinc finger protein 585B 2 4
MIRT673390 ZNF124 zinc finger protein 124 2 2
MIRT673452 ZNF583 zinc finger protein 583 2 2
MIRT673917 DCTN6 dynactin subunit 6 2 2
MIRT673952 ZNF500 zinc finger protein 500 2 2
MIRT674102 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT674167 BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 2 2
MIRT674206 FUT2 fucosyltransferase 2 2 2
MIRT674452 PURB purine rich element binding protein B 2 4
MIRT674687 PLCE1 phospholipase C epsilon 1 2 2
MIRT674701 TMEM59 transmembrane protein 59 2 2
MIRT674800 NPR1 natriuretic peptide receptor 1 2 4
MIRT675247 MAK male germ cell associated kinase 2 2
MIRT676012 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT676374 APTX aprataxin 2 2
MIRT676834 TNFSF15 TNF superfamily member 15 2 2
MIRT678193 CRCP CGRP receptor component 2 2
MIRT678293 PTRH2 peptidyl-tRNA hydrolase 2 2 2
MIRT679532 RAB36 RAB36, member RAS oncogene family 2 2
MIRT679669 RABAC1 Rab acceptor 1 2 2
MIRT679850 GPR75 G protein-coupled receptor 75 2 2
MIRT680533 PRIM2 DNA primase subunit 2 2 2
MIRT680563 ZNF584 zinc finger protein 584 2 2
MIRT680577 PGPEP1 pyroglutamyl-peptidase I 2 2
MIRT680849 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT680888 MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1 like 2 2
MIRT680940 EVC EvC ciliary complex subunit 1 2 2
MIRT680964 SLC15A1 solute carrier family 15 member 1 2 4
MIRT681017 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT681065 PAQR7 progestin and adipoQ receptor family member 7 2 2
MIRT681209 ZNF638 zinc finger protein 638 2 2
MIRT681291 RFC2 replication factor C subunit 2 2 2
MIRT681366 BRI3BP BRI3 binding protein 2 2
MIRT681517 STAT2 signal transducer and activator of transcription 2 2 2
MIRT681549 ZNF738 zinc finger protein 738 2 2
MIRT681574 ABHD15 abhydrolase domain containing 15 2 2
MIRT681597 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT681806 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681912 SLC11A2 solute carrier family 11 member 2 2 2
MIRT681953 SLC19A3 solute carrier family 19 member 3 2 2
MIRT682037 AGXT2 alanine--glyoxylate aminotransferase 2 2 4
MIRT682111 ITGA3 integrin subunit alpha 3 2 4
MIRT682190 SLC38A7 solute carrier family 38 member 7 2 2
MIRT682247 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682394 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682554 EXOSC2 exosome component 2 2 2
MIRT682665 CASP8 caspase 8 2 2
MIRT683283 ZNF99 zinc finger protein 99 2 2
MIRT683359 SCARF1 scavenger receptor class F member 1 2 2
MIRT683453 ACOT2 acyl-CoA thioesterase 2 2 2
MIRT683596 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT683661 ZNF695 zinc finger protein 695 2 2
MIRT683770 CPE carboxypeptidase E 2 2
MIRT683807 NOTO notochord homeobox 2 2
MIRT684462 MFSD4 major facilitator superfamily domain containing 4A 2 2
MIRT684525 C1orf174 chromosome 1 open reading frame 174 2 2
MIRT684985 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT685012 CXorf56 chromosome X open reading frame 56 2 2
MIRT685072 GEMIN4 gem nuclear organelle associated protein 4 2 2
MIRT685115 DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 2 2
MIRT685477 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT685831 SLC27A1 solute carrier family 27 member 1 2 2
MIRT686032 UMPS uridine monophosphate synthetase 2 2
MIRT686559 TPM3 tropomyosin 3 2 2
MIRT687287 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT687309 OTUD7B OTU deubiquitinase 7B 2 2
MIRT688085 GLUL glutamate-ammonia ligase 2 2
MIRT688168 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT688584 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT688601 CYCS cytochrome c, somatic 2 2
MIRT688921 C11orf84 chromosome 11 open reading frame 84 2 2
MIRT689285 C5AR2 complement component 5a receptor 2 2 2
MIRT689622 AKAP6 A-kinase anchoring protein 6 2 2
MIRT690051 C6orf141 chromosome 6 open reading frame 141 2 2
MIRT690224 C5orf45 MRN complex interacting protein 2 2
MIRT690272 CAMLG calcium modulating ligand 2 2
MIRT690331 MRPS30 mitochondrial ribosomal protein S30 2 2
MIRT690480 ZNF33A zinc finger protein 33A 2 2
MIRT690526 ZNF566 zinc finger protein 566 2 2
MIRT690581 MICA MHC class I polypeptide-related sequence A 2 2
MIRT690675 RPF2 ribosome production factor 2 homolog 2 2
MIRT690790 ZNF589 zinc finger protein 589 2 2
MIRT690873 PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 2 2
MIRT691142 HJURP Holliday junction recognition protein 2 2
MIRT691158 APOL6 apolipoprotein L6 2 2
MIRT691288 CENPM centromere protein M 2 2
MIRT691435 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT691749 IKBKG inhibitor of nuclear factor kappa B kinase subunit gamma 2 2
MIRT691833 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT691885 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT691947 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT692047 PAK1IP1 PAK1 interacting protein 1 2 2
MIRT692668 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT692767 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 2 2
MIRT692859 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT693122 SCNM1 sodium channel modifier 1 2 2
MIRT693514 MOB3A MOB kinase activator 3A 2 2
MIRT693648 ACBD7 acyl-CoA binding domain containing 7 2 2
MIRT693688 MXRA7 matrix remodeling associated 7 2 2
MIRT694078 RNASEH2B ribonuclease H2 subunit B 2 2
MIRT694163 SLC36A2 solute carrier family 36 member 2 2 2
MIRT694262 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT694506 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT694556 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT694639 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT694710 CD300LG CD300 molecule like family member g 2 2
MIRT694753 LLGL1 LLGL1, scribble cell polarity complex component 2 2
MIRT694896 ZNF417 zinc finger protein 417 2 2
MIRT695158 BTD biotinidase 2 2
MIRT695275 CD209 CD209 molecule 2 2
MIRT695434 TCF23 transcription factor 23 2 2
MIRT695817 SRD5A1 steroid 5 alpha-reductase 1 2 2
MIRT696008 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT696345 SLC35D2 solute carrier family 35 member D2 2 2
MIRT696368 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT696533 C3 complement C3 2 2
MIRT696779 DHODH dihydroorotate dehydrogenase (quinone) 2 2
MIRT697075 PSMC4 proteasome 26S subunit, ATPase 4 2 2
MIRT697498 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT697630 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT697931 TXNDC16 thioredoxin domain containing 16 2 2
MIRT697966 TSPYL1 TSPY like 1 2 2
MIRT698237 TMEM216 transmembrane protein 216 2 2
MIRT698643 TES testin LIM domain protein 2 2
MIRT698661 TERF2 telomeric repeat binding factor 2 2 2
MIRT698974 SPAST spastin 2 2
MIRT699047 SOAT1 sterol O-acyltransferase 1 2 2
MIRT699193 SLX4IP SLX4 interacting protein 2 2
MIRT699586 SIKE1 suppressor of IKBKE 1 2 2
MIRT699759 SEPHS1 selenophosphate synthetase 1 2 2
MIRT700350 RAB4A RAB4A, member RAS oncogene family 2 2
MIRT700402 RAB13 RAB13, member RAS oncogene family 2 2
MIRT700418 QDPR quinoid dihydropteridine reductase 2 2
MIRT700546 PTBP2 polypyrimidine tract binding protein 2 2 2
MIRT700774 PLA2G4A phospholipase A2 group IVA 2 2
MIRT700875 PER2 period circadian clock 2 2 2
MIRT700952 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT701077 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT701172 PACS2 phosphofurin acidic cluster sorting protein 2 2 2
MIRT701479 NEK9 NIMA related kinase 9 2 2
MIRT701661 MYH9 myosin heavy chain 9 2 2
MIRT701779 MSL2 MSL complex subunit 2 2 2
MIRT702137 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2 2
MIRT702494 KIAA1328 KIAA1328 2 2
MIRT703058 GTPBP10 GTP binding protein 10 2 2
MIRT703224 GOLGA3 golgin A3 2 2
MIRT703620 FBXO45 F-box protein 45 2 2
MIRT703657 FAM60A SIN3-HDAC complex associated factor 2 2
MIRT703765 FAM118A family with sequence similarity 118 member A 2 2
MIRT703832 EVI5 ecotropic viral integration site 5 2 2
MIRT703862 ERN1 endoplasmic reticulum to nucleus signaling 1 2 2
MIRT704664 CLCC1 chloride channel CLIC like 1 2 2
MIRT704812 CDC73 cell division cycle 73 2 2
MIRT705608 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT705625 AP1S3 adaptor related protein complex 1 sigma 3 subunit 2 2
MIRT705682 ANKRD40 ankyrin repeat domain 40 2 2
MIRT705813 AKNA AT-hook transcription factor 2 2
MIRT706238 SYT15 synaptotagmin 15 2 2
MIRT706567 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 2 2
MIRT709657 DFFB DNA fragmentation factor subunit beta 2 2
MIRT710609 ZNF555 zinc finger protein 555 2 2
MIRT711717 IREB2 iron responsive element binding protein 2 2 2
MIRT714122 TMED9 transmembrane p24 trafficking protein 9 2 2
MIRT715204 FKTN fukutin 2 2
MIRT718260 ZDHHC8 zinc finger DHHC-type containing 8 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4419b Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4419b Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4419b Cisplatin + Decitabine resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-mir-4419b Androstenedione+Anastrozole sensitive cell line (MCF-7)

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