miRTarBase - #MIRT699988


—
pre-miRNA Information
pre-miRNA hsa-mir-1301   
Genomic Coordinates chr2: 25328640 - 25328721
Synonyms MIRN1301, hsa-mir-1301, MIR1301
Description Homo sapiens miR-1301 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-1301-3p
Sequence 48| UUGCAGCUGCCUGGGAGUGACUUC |71
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 5 2 - 25328670 26449202, 27298257, 28411194, 28550310, 28855684, 29267965, 29950133, 29165639, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs775188648 6 dbSNP
rs1022364375 11 dbSNP
rs938368115 12 dbSNP
rs771728471 15 dbSNP
rs778709428 19 dbSNP
rs1358947891 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol RPS24   
Synonyms DBA3, S24
Description ribosomal protein S24
Transcript NM_001142285   
Other Transcripts NM_001026 , NM_001142282 , NM_001142284 , NM_001142283 , NM_033022   
Expression
Putative miRNA Targets on RPS24
3'UTR of RPS24
(miRNA target sites are highlighted)		 
>RPS24|NM_001142285|3'UTR
   1 TGTCACTGCCATGGCCGCCTTGCTGCATTTCTGAGGATGCTTCATCTCTCCACCTTCTTCTCCACTCAGCAGCCAGCAGG
  81 GCACTGTGGAAATCGGAGTCACATGAGCTGGCACCTCTGTTCAGAACCCTCCAGGGCTCCACATCTCTCTCACCCAAATG
 161 CCAAAGACCTCCCCACGCCCCCACAATCCCCCACGACCTGGCCACTGGCCTCCCACCACCTTCCAGCTCCAGCGGCTCCT
 241 ACCACATTTAAGGCTTTCCTTCCTAGTTTTAATTTTTCCTCGTCAGCAGTTGATTTTATTATTTTCTTGTTTATTGGTAT
 321 TTTCCCACTAGAAATGAAGCTGCGTGAAGTTAGAGATTTTTTTTTTTGGTCTGTGTTCCTAATTAGCTCATTGCTATACC
 401 CCTGGCGCCCAGAACAATGCCTTGGACACAGTACGCAGTAGACTAAATAAATACTTGTTGAATGACTGACTGACGGAATG
 481 ACGGCTGTGTGGGGAGTGGATTGGGTCGTGAGGCAGAGGCTGCGGTGGAAACTCAGGCAGGAGGTGATGGTGGTTCTTGG
 561 GGCTGCGGAATGCCAAGTTTAGAAGCTCTTCCTCTGCTGTGGCACATGAACCGGTCACTCGAGAAGGCTTTTAGATTTAC
 641 TTTGCCTAATCCCCTCTTAGTGCATGTGGGGAAACTGAGGTACACAAAAGGAATTCCCCACCAAGTTAGGGGCAGAACCT
 721 AGCCCCCTTGTCTCCCAGATGGATATCTTCTTTTTTTTTTGAGACGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGT
 801 GGTACCATCTTGGCTCACTGCAACCTCTGCTTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTGTCTGCGAT
 881 TACAGGTGCACACAACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTGGTCAGGGTGACC
 961 TCAAACTCCTGACCTCATGATCCACCCAGCTCAGCCTCCCAACGTGCTGGGATTACAGGCATGAGCCACCGTGCCTGGCT
1041 GGACATCTTGTTATTAAAGCTTCTTCTCTCTTTGTAGGGGAGGGGGAGATGCCTCTGGTGGAGAAGACCAGTGTGGCAGT
1121 GACTGTGTCTGTTAGTGAACCTGGTGGCTGGTTGAGGGTCTGTCGTGGTGACTGAGGACACATACAAAGTGCTTTTCTCA
1201 GTGGTCACCTTGGTGTTGGTGAATAAGGGTCAGAAGATGGCTCCTGTCCTAGGGCACTGCCAGTCGGTTTGGAAGCTGAA
1281 ATGCCTGCTTAGCAGTTTGAGGAAACACAGACCTTGGAGGATCTTCTGGTTGCCTCTTCAAGAATTCATTCTATTCCCCT
1361 TCTGCTCCCCAAATTTGCTTTTCTTGGGGTGGGTCTTGGTTGGCCTAAGCCAAGAAAGTATGGCATCTACTCCTTCCATA
1441 GCAATAGCTCAGGAATAGGCAGTGACCCAGACCTGAACCAATCAGTGCATGGAATTACCCCTGGCCAAAGTGGTTGATTG
1521 AGGCTGGGTGCAAGCAGAGTTGTGAGAAGGCTCCCATTTGGTGGTTGGAGAGATCGCACTTGCTCCAGAGGTCATAATGT
1601 GCAGATCTGAGGCTTGGAACTGCTGCAGACATTTTGCTACCACAAGTGAAGCCACCCTGACGACACAGTTGACAATTTGG
1681 AGCAGGGCAGAGCTGAGAGAACAGCAGGGAAACAGCCAGAGTCTTGCTCAAGCCTCCCTGAAGTATCTATACCCCTGGAC
1761 TCTAGTTATGGGGGCTAATAAATGTTATATACTGTTTAAGGTAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuuCAGUGAGGGU-CCG-----UCGACGUu 5'
             |||||| ||| |||      |||||| 
Target 5' --tGTCACTGCCATGGCCGCCTTGCTGCAt 3'
 1 - 28 141.00 -24.40
2 
miRNA  3' cuUCAGUGAG-GGUC----CGUCGACGUu 5'
            | |: | | |:||    | ||||||: 
Target 5' gtATTTTCCCACTAGAAATGAAGCTGCGt 3'
 317 - 345 132.00 -15.12
3 
miRNA  3' cuUCAGUGAGGGUCCGUCGACGUu 5'
            ||||: |::  || ||||| | 
Target 5' ccAGTCGGTTT--GGAAGCTGAAa 3'
 1260 - 1281 130.00 -14.62
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1187759 101 ClinVar
COSN31587210 39 COSMIC
COSN17370154 95 COSMIC
COSN1122889 332 COSMIC
COSN17606784 408 COSMIC
COSN17182052 875 COSMIC
COSN23453092 1005 COSMIC
COSN27091365 1032 COSMIC
COSN8189869 1166 COSMIC
COSN19493751 1318 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs536067246 11 dbSNP
rs183560808 12 dbSNP
rs1461562425 13 dbSNP
rs769160910 17 dbSNP
rs765237160 18 dbSNP
rs1394569670 22 dbSNP
rs939483296 26 dbSNP
rs1354588689 38 dbSNP
rs1453945212 40 dbSNP
rs1385664506 61 dbSNP
rs566667298 62 dbSNP
rs1286545030 69 dbSNP
rs532561240 77 dbSNP
rs992187317 78 dbSNP
rs538598613 95 dbSNP
rs1423505183 96 dbSNP
rs1422410713 97 dbSNP
rs114149556 101 dbSNP
rs1163989263 101 dbSNP
rs1446330450 104 dbSNP
rs1031462188 106 dbSNP
rs142851690 116 dbSNP
rs537930998 129 dbSNP
rs925561105 130 dbSNP
rs763076568 135 dbSNP
rs1219055451 143 dbSNP
rs1489924638 146 dbSNP
rs1052652717 148 dbSNP
rs1307524226 154 dbSNP
rs1247207476 155 dbSNP
rs554751714 156 dbSNP
rs1406691537 165 dbSNP
rs1291773480 166 dbSNP
rs915650254 168 dbSNP
rs377427583 176 dbSNP
rs540845064 178 dbSNP
rs560812258 179 dbSNP
rs973069775 185 dbSNP
rs1214980791 187 dbSNP
rs899554259 188 dbSNP
rs995179101 190 dbSNP
rs1297221370 193 dbSNP
rs1026609954 195 dbSNP
rs188440005 196 dbSNP
rs1226955895 201 dbSNP
rs151068494 206 dbSNP
rs1169651311 207 dbSNP
rs562732070 210 dbSNP
rs1429108412 213 dbSNP
rs1420243838 216 dbSNP
rs1195938663 217 dbSNP
rs1490717713 220 dbSNP
rs1225355735 226 dbSNP
rs1245532230 231 dbSNP
rs1035553838 234 dbSNP
rs531644670 235 dbSNP
rs1421857405 237 dbSNP
rs1447890240 240 dbSNP
rs751662641 247 dbSNP
rs1204374145 254 dbSNP
rs916674466 264 dbSNP
rs1385927846 280 dbSNP
rs548257521 282 dbSNP
rs1162556840 283 dbSNP
rs561879004 287 dbSNP
rs1283492425 291 dbSNP
rs1406461844 302 dbSNP
rs140313250 311 dbSNP
rs1297406772 317 dbSNP
rs1462373005 318 dbSNP
rs969406125 336 dbSNP
rs529802136 337 dbSNP
rs925269207 345 dbSNP
rs1428727940 356 dbSNP
rs1177022006 357 dbSNP
rs1481219401 357 dbSNP
rs35734754 357 dbSNP
rs397828117 357 dbSNP
rs576615131 357 dbSNP
rs5786317 357 dbSNP
rs200785086 369 dbSNP
rs1362500716 371 dbSNP
rs1433902126 372 dbSNP
rs1315380892 374 dbSNP
rs1360953795 376 dbSNP
rs1226156963 379 dbSNP
rs750225211 382 dbSNP
rs546497651 384 dbSNP
rs566736490 385 dbSNP
rs1234889647 392 dbSNP
rs996897418 403 dbSNP
rs192833809 407 dbSNP
rs753015915 408 dbSNP
rs1391779589 415 dbSNP
rs1334567228 418 dbSNP
rs141004459 421 dbSNP
rs1244015821 427 dbSNP
rs1177257356 432 dbSNP
rs1467741870 435 dbSNP
rs552483529 436 dbSNP
rs1158720478 438 dbSNP
rs150188824 444 dbSNP
rs1240488898 447 dbSNP
rs995251050 448 dbSNP
rs778227693 454 dbSNP
rs1048092311 467 dbSNP
rs1243148106 471 dbSNP
rs886760564 473 dbSNP
rs139078073 475 dbSNP
rs1003861379 476 dbSNP
rs1355574358 478 dbSNP
rs370707915 483 dbSNP
rs1401225209 488 dbSNP
rs1161289396 492 dbSNP
rs1036031371 508 dbSNP
rs758150474 509 dbSNP
rs1382936303 517 dbSNP
rs1288506665 519 dbSNP
rs959916608 520 dbSNP
rs1162064743 521 dbSNP
rs749862750 524 dbSNP
rs555857874 525 dbSNP
rs920397595 528 dbSNP
rs184005974 537 dbSNP
rs541091857 548 dbSNP
rs559326016 560 dbSNP
rs979474722 567 dbSNP
rs80146678 568 dbSNP
rs1289276416 581 dbSNP
rs1245007766 585 dbSNP
rs1359951649 589 dbSNP
rs1283106992 590 dbSNP
rs956938656 593 dbSNP
rs944312907 598 dbSNP
rs376774408 608 dbSNP
rs1041170386 609 dbSNP
rs142271202 613 dbSNP
rs79628312 614 dbSNP
rs1362724248 621 dbSNP
rs146163875 622 dbSNP
rs1366622738 627 dbSNP
rs1165502575 653 dbSNP
rs975615917 658 dbSNP
rs999247293 661 dbSNP
rs576010402 666 dbSNP
rs921422212 667 dbSNP
rs1478572455 676 dbSNP
rs1266301701 682 dbSNP
rs931078255 684 dbSNP
rs376530939 685 dbSNP
rs1208526499 688 dbSNP
rs1291836427 692 dbSNP
rs1014193593 693 dbSNP
rs1022765546 706 dbSNP
rs1269629552 713 dbSNP
rs1342501895 721 dbSNP
rs188152089 724 dbSNP
rs534205505 725 dbSNP
rs1263933324 726 dbSNP
rs1325953470 727 dbSNP
rs994715049 735 dbSNP
rs1444354671 743 dbSNP
rs1027806207 746 dbSNP
rs1426681959 750 dbSNP
rs1466705686 750 dbSNP
rs1248171977 751 dbSNP
rs950522402 751 dbSNP
rs983500676 751 dbSNP
rs1236974847 752 dbSNP
rs1437112414 752 dbSNP
rs1470588459 756 dbSNP
rs746551338 761 dbSNP
rs768158540 766 dbSNP
rs939692587 767 dbSNP
rs1409722143 778 dbSNP
rs1472119301 783 dbSNP
rs1056762584 787 dbSNP
rs776466271 799 dbSNP
rs911573546 802 dbSNP
rs1412407230 811 dbSNP
rs1335590104 814 dbSNP
rs1332629085 816 dbSNP
rs1333160985 821 dbSNP
rs965564610 821 dbSNP
rs1175094376 826 dbSNP
rs1354587943 829 dbSNP
rs1443792467 831 dbSNP
rs895776879 836 dbSNP
rs976972657 838 dbSNP
rs1156495795 839 dbSNP
rs1012778782 844 dbSNP
rs1022783083 847 dbSNP
rs368869583 853 dbSNP
rs747936688 856 dbSNP
rs1241278520 859 dbSNP
rs932803386 860 dbSNP
rs1000008423 863 dbSNP
rs1443129925 871 dbSNP
rs372435023 878 dbSNP
rs546732599 879 dbSNP
rs376462651 881 dbSNP
rs1350396976 883 dbSNP
rs560079260 886 dbSNP
rs1310467500 887 dbSNP
rs1242867866 889 dbSNP
rs773275465 891 dbSNP
rs370982100 895 dbSNP
rs1347665931 900 dbSNP
rs1019621932 901 dbSNP
rs1315779742 914 dbSNP
rs1399809237 915 dbSNP
rs1380615405 924 dbSNP
rs532383532 927 dbSNP
rs895823204 930 dbSNP
rs1438439603 932 dbSNP
rs373650390 933 dbSNP
rs1483618483 943 dbSNP
rs921453437 944 dbSNP
rs931483761 949 dbSNP
rs1446644249 954 dbSNP
rs1287141600 960 dbSNP
rs1219276340 963 dbSNP
rs1482696344 966 dbSNP
rs984273021 968 dbSNP
rs545328381 970 dbSNP
rs1044329282 974 dbSNP
rs1431136932 975 dbSNP
rs552165146 991 dbSNP
rs1380688893 993 dbSNP
rs563433674 1001 dbSNP
rs774242599 1003 dbSNP
rs995059685 1005 dbSNP
rs1027506479 1011 dbSNP
rs1422484706 1012 dbSNP
rs1364806812 1017 dbSNP
rs191450498 1018 dbSNP
rs1165384911 1021 dbSNP
rs1057235655 1031 dbSNP
rs142817294 1032 dbSNP
rs1415967896 1033 dbSNP
rs948663403 1046 dbSNP
rs1184889609 1051 dbSNP
rs1477591460 1060 dbSNP
rs1264145876 1062 dbSNP
rs1004641715 1063 dbSNP
rs1305652533 1066 dbSNP
rs1044310589 1069 dbSNP
rs904420043 1075 dbSNP
rs974416079 1077 dbSNP
rs548211729 1079 dbSNP
rs568123369 1088 dbSNP
rs533643051 1090 dbSNP
rs767694787 1092 dbSNP
rs1031465124 1099 dbSNP
rs1270221823 1102 dbSNP
rs892584012 1103 dbSNP
rs530762984 1107 dbSNP
rs1279698176 1109 dbSNP
rs367614489 1114 dbSNP
rs1231587684 1115 dbSNP
rs1344576892 1118 dbSNP
rs1293902048 1119 dbSNP
rs1459343913 1121 dbSNP
rs1274450265 1122 dbSNP
rs1465140356 1124 dbSNP
rs1424505406 1126 dbSNP
rs1196099201 1128 dbSNP
rs1479586211 1134 dbSNP
rs867904909 1141 dbSNP
rs1192166194 1144 dbSNP
rs1489724325 1155 dbSNP
rs1231645262 1165 dbSNP
rs184653314 1166 dbSNP
rs934707405 1172 dbSNP
rs1272581269 1192 dbSNP
rs558629854 1198 dbSNP
rs1322436954 1229 dbSNP
rs1388274711 1245 dbSNP
rs1028589499 1250 dbSNP
rs1447495630 1258 dbSNP
rs756456098 1263 dbSNP
rs952957182 1266 dbSNP
rs778443160 1267 dbSNP
rs1177114577 1272 dbSNP
rs984737349 1286 dbSNP
rs1449614760 1287 dbSNP
rs1197927236 1288 dbSNP
rs917372303 1289 dbSNP
rs1458612397 1302 dbSNP
rs1239426881 1303 dbSNP
rs570932075 1309 dbSNP
rs1450945360 1310 dbSNP
rs1166397743 1313 dbSNP
rs189427997 1327 dbSNP
rs961447944 1329 dbSNP
rs992573171 1337 dbSNP
rs1389000855 1344 dbSNP
rs916975010 1349 dbSNP
rs948402121 1353 dbSNP
rs1164744280 1360 dbSNP
rs764378203 1365 dbSNP
rs34882908 1367 dbSNP
rs1308276256 1371 dbSNP
rs754243903 1373 dbSNP
rs905750894 1378 dbSNP
rs541773408 1390 dbSNP
rs757656799 1393 dbSNP
rs1049334050 1396 dbSNP
rs1467789776 1399 dbSNP
rs1158455860 1440 dbSNP
rs182204054 1441 dbSNP
rs1382678773 1443 dbSNP
rs1295736471 1445 dbSNP
rs1182335896 1454 dbSNP
rs1004714906 1471 dbSNP
rs372559137 1482 dbSNP
rs901630890 1486 dbSNP
rs891611010 1488 dbSNP
rs1284991414 1490 dbSNP
rs1217087271 1499 dbSNP
rs1355645043 1503 dbSNP
rs1312789190 1511 dbSNP
rs995781321 1512 dbSNP
rs779505990 1520 dbSNP
rs954412460 1538 dbSNP
rs1354181005 1539 dbSNP
rs1397969106 1545 dbSNP
rs1383105675 1549 dbSNP
rs1208948166 1550 dbSNP
rs374053277 1565 dbSNP
rs979045649 1569 dbSNP
rs1041167884 1576 dbSNP
rs541162646 1577 dbSNP
rs1189054660 1579 dbSNP
rs1426312255 1583 dbSNP
rs111858017 1594 dbSNP
rs901225533 1598 dbSNP
rs1186258198 1604 dbSNP
rs1247074579 1618 dbSNP
rs564632056 1620 dbSNP
rs1208384403 1622 dbSNP
rs1489144836 1625 dbSNP
rs996854601 1627 dbSNP
rs1370649775 1628 dbSNP
rs917319833 1638 dbSNP
rs746474413 1639 dbSNP
rs950130375 1642 dbSNP
rs1338572150 1643 dbSNP
rs1277802754 1644 dbSNP
rs1400904523 1646 dbSNP
rs1389827812 1651 dbSNP
rs980068432 1656 dbSNP
rs144563855 1657 dbSNP
rs1392109377 1659 dbSNP
rs1318734691 1662 dbSNP
rs546001875 1663 dbSNP
rs1453386690 1667 dbSNP
rs1170879341 1669 dbSNP
rs930514448 1676 dbSNP
rs1314946746 1683 dbSNP
rs1048971901 1691 dbSNP
rs1243959749 1702 dbSNP
rs886391145 1710 dbSNP
rs148004038 1714 dbSNP
rs1316133463 1718 dbSNP
rs1257517034 1720 dbSNP
rs1219408064 1722 dbSNP
rs1040208700 1725 dbSNP
rs7092702 1730 dbSNP
rs1332077754 1738 dbSNP
rs1326099782 1739 dbSNP
rs7076705 1745 dbSNP
rs1398840774 1749 dbSNP
rs992929620 1750 dbSNP
rs1331480647 1753 dbSNP
rs1029042508 1754 dbSNP
rs1422598353 1758 dbSNP
rs773080700 1759 dbSNP
rs1461505031 1762 dbSNP
rs1379212828 1769 dbSNP
rs368620011 1778 dbSNP
rs1179501755 1785 dbSNP
rs1457264946 1795 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000435275.1 | 3UTR | GGAGAUUGGAUCACAGccgaaggaguaaAGGUGCUGCAAUGAUGUUAGCUGUGGCCACUGUGGAUUUUUCGCAAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
CHOL -0.896 0 -0.850 0 9 Click to see details
STAD -0.435 0.01 -0.385 0.01 32 Click to see details
ESCA -0.483 0.07 -0.291 0.19 11 Click to see details
KIRP -0.266 0.07 -0.124 0.25 32 Click to see details
COAD -0.468 0.12 -0.381 0.18 8 Click to see details
LUAD -0.355 0.13 -0.252 0.21 12 Click to see details
HNSC -0.17 0.14 -0.227 0.07 42 Click to see details
CESC -0.902 0.14 -1.000 0.5 3 Click to see details
KIRC -0.131 0.14 -0.171 0.08 68 Click to see details
UCEC -0.197 0.21 -0.154 0.26 19 Click to see details
THCA -0.105 0.21 -0.189 0.08 59 Click to see details
PCPG -0.781 0.21 -1.000 0.5 3 Click to see details
PRAD -0.092 0.26 -0.002 0.49 50 Click to see details
BRCA 0.068 0.27 0.054 0.31 84 Click to see details
PAAD -0.317 0.34 0.400 0.3 4 Click to see details
BLCA 0.093 0.36 0.104 0.34 18 Click to see details
LUSC -0.051 0.38 -0.027 0.44 38 Click to see details
LIHC 0.044 0.38 0.099 0.25 49 Click to see details
KICH 0.037 0.43 -0.081 0.35 25 Click to see details
KICH 0.037 0.43 -0.081 0.35 25 Click to see details
KICH 0.037 0.43 -0.081 0.35 25 Click to see details
195 hsa-miR-1301-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT035957 MRPL10 mitochondrial ribosomal protein L10 1 1
MIRT035958 ZNF816 zinc finger protein 816 1 1
MIRT035959 HDLBP high density lipoprotein binding protein 1 1
MIRT035960 GNG10 G protein subunit gamma 10 1 1
MIRT035961 MICALL1 MICAL like 1 1 1
MIRT035962 CCNH cyclin H 1 1
MIRT035963 RAD23B RAD23 homolog B, nucleotide excision repair protein 1 1
MIRT035964 HIST2H2AC histone cluster 2 H2A family member c 1 1
MIRT035965 PARL presenilin associated rhomboid like 1 1
MIRT035966 TXN thioredoxin 1 1
MIRT035967 CREBBP CREB binding protein 1 1
MIRT035968 CYTB cytochrome b 1 1
MIRT035969 GLI3 GLI family zinc finger 3 1 1
MIRT035970 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 1 1
MIRT035971 PREP prolyl endopeptidase 1 1
MIRT035972 COL6A1 collagen type VI alpha 1 chain 1 1
MIRT035973 ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1 1
MIRT035974 ADCY3 adenylate cyclase 3 1 1
MIRT035975 POLB DNA polymerase beta 1 1
MIRT035976 HMGA1 high mobility group AT-hook 1 1 1
MIRT035977 SKP1 S-phase kinase associated protein 1 1 1
MIRT035978 ADD2 adducin 2 1 1
MIRT035979 ANXA11 annexin A11 1 1
MIRT035980 CORO1C coronin 1C 1 1
MIRT035981 MDH2 malate dehydrogenase 2 1 1
MIRT035982 BICD2 BICD cargo adaptor 2 1 1
MIRT035983 SPTBN1 spectrin beta, non-erythrocytic 1 1 1
MIRT035984 CDK5RAP2 CDK5 regulatory subunit associated protein 2 1 1
MIRT035985 POLR3H RNA polymerase III subunit H 1 1
MIRT035986 COX1 cytochrome c oxidase subunit I 1 1
MIRT035987 HEATR2 dynein axonemal assembly factor 5 1 1
MIRT035988 RPS5 ribosomal protein S5 1 1
MIRT035989 CCT3 chaperonin containing TCP1 subunit 3 1 1
MIRT035990 YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta 1 1
MIRT035991 RPL3 ribosomal protein L3 1 1
MIRT035992 TMPO thymopoietin 1 1
MIRT035993 COPE coatomer protein complex subunit epsilon 1 1
MIRT035994 NONO non-POU domain containing octamer binding 1 1
MIRT035995 BLCAP bladder cancer associated protein 1 1
MIRT035996 NUP133 nucleoporin 133 1 1
MIRT035997 VCP valosin containing protein 1 1
MIRT035998 ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 1 1
MIRT035999 SON SON DNA binding protein 1 1
MIRT036000 ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex subunit F6 1 1
MIRT036001 VIM vimentin 1 1
MIRT036002 FKBP8 FK506 binding protein 8 1 1
MIRT036003 SPECC1L sperm antigen with calponin homology and coiled-coil domains 1 like 1 1
MIRT036004 ZCCHC14 zinc finger CCHC-type containing 14 1 1
MIRT036005 TXNL4A thioredoxin like 4A 1 1
MIRT036006 UBE2J2 ubiquitin conjugating enzyme E2 J2 1 1
MIRT036007 FOPNL FGFR1OP N-terminal like 1 1
MIRT036008 VDAC1 voltage dependent anion channel 1 1 1
MIRT036009 CDIP1 cell death inducing p53 target 1 1 1
MIRT036010 EBNA1BP2 EBNA1 binding protein 2 1 1
MIRT036011 CD276 CD276 molecule 1 1
MIRT036012 RPS2 ribosomal protein S2 1 1
MIRT036013 USP28 ubiquitin specific peptidase 28 1 1
MIRT036014 ZMIZ1 zinc finger MIZ-type containing 1 1 1
MIRT036015 B4GALT7 beta-1,4-galactosyltransferase 7 1 1
MIRT036016 CAND1 cullin associated and neddylation dissociated 1 1 1
MIRT036017 CCDC104 cilia and flagella associated protein 36 1 1
MIRT036018 IMPDH1 inosine monophosphate dehydrogenase 1 1 1
MIRT036019 ATXN2L ataxin 2 like 1 1
MIRT036020 PARP1 poly(ADP-ribose) polymerase 1 1 1
MIRT036021 TNXB tenascin XB 1 1
MIRT036022 SYNGR1 synaptogyrin 1 1 1
MIRT036023 TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 1 1
MIRT036024 ATXN7L3B ataxin 7 like 3B 1 1
MIRT036025 BCL2L13 BCL2 like 13 1 1
MIRT036026 RBM42 RNA binding motif protein 42 1 1
MIRT036027 HDGF heparin binding growth factor 1 1
MIRT036028 NAT8L N-acetyltransferase 8 like 1 1
MIRT036029 DLST dihydrolipoamide S-succinyltransferase 1 1
MIRT036030 CEP104 centrosomal protein 104 1 1
MIRT036031 NCOR1 nuclear receptor corepressor 1 1 1
MIRT036032 COCH cochlin 1 1
MIRT036033 NUTF2 nuclear transport factor 2 1 1
MIRT036034 KMT2E lysine methyltransferase 2E 1 1
MIRT036035 RANGAP1 Ran GTPase activating protein 1 1 1
MIRT036036 SEPHS2 selenophosphate synthetase 2 1 1
MIRT036037 DYNC1I2 dynein cytoplasmic 1 intermediate chain 2 1 1
MIRT036038 ZCCHC24 zinc finger CCHC-type containing 24 1 1
MIRT036039 TRRAP transformation/transcription domain associated protein 1 1
MIRT036040 INPP4A inositol polyphosphate-4-phosphatase type I A 1 1
MIRT036041 CHN1 chimerin 1 1 1
MIRT036042 FECH ferrochelatase 1 1
MIRT036043 DCTD dCMP deaminase 1 1
MIRT036044 UBA1 ubiquitin like modifier activating enzyme 1 1 1
MIRT036045 PKM pyruvate kinase, muscle 1 1
MIRT036046 SSRP1 structure specific recognition protein 1 1 1
MIRT036047 CELF1 CUGBP Elav-like family member 1 1 1
MIRT036048 TSR2 TSR2, ribosome maturation factor 1 1
MIRT036049 TP53BP2 tumor protein p53 binding protein 2 1 1
MIRT036050 GSG2 histone H3 associated protein kinase 1 1
MIRT036051 WDFY1 WD repeat and FYVE domain containing 1 1 1
MIRT036052 RPA1 replication protein A1 1 1
MIRT036053 TMEM41A transmembrane protein 41A 1 1
MIRT036054 BIRC5 baculoviral IAP repeat containing 5 1 1
MIRT036055 NOP2 NOP2 nucleolar protein 1 1
MIRT036056 PEF1 penta-EF-hand domain containing 1 1 1
MIRT036057 CYB5D1 cytochrome b5 domain containing 1 1 1
MIRT036058 HIGD1A HIG1 hypoxia inducible domain family member 1A 1 1
MIRT036059 WDR61 WD repeat domain 61 1 1
MIRT036060 MINK1 misshapen like kinase 1 1 1
MIRT036061 RPL35A ribosomal protein L35a 1 1
MIRT036062 WNT3 Wnt family member 3 1 1
MIRT036063 SYNJ2 synaptojanin 2 1 1
MIRT036064 CFL1 cofilin 1 1 1
MIRT036065 ALDOA aldolase, fructose-bisphosphate A 1 1
MIRT036066 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 1 1
MIRT064841 ZBTB18 zinc finger and BTB domain containing 18 2 4
MIRT090782 MBNL1 muscleblind like splicing regulator 1 2 2
MIRT163227 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 2
MIRT214143 LMNB1 lamin B1 2 2
MIRT291875 ZNF333 zinc finger protein 333 2 2
MIRT292477 ZNF507 zinc finger protein 507 2 2
MIRT306035 SKIL SKI like proto-oncogene 2 2
MIRT443004 TRIOBP TRIO and F-actin binding protein 2 2
MIRT457830 ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein 2 2
MIRT460067 RFTN2 raftlin family member 2 2 2
MIRT460342 ARL14EP ADP ribosylation factor like GTPase 14 effector protein 2 2
MIRT463060 ZNF639 zinc finger protein 639 2 2
MIRT466204 TMED10 transmembrane p24 trafficking protein 10 2 2
MIRT476159 GOLGA8B golgin A8 family member B 2 2
MIRT486953 HLA-B major histocompatibility complex, class I, B 2 2
MIRT492391 SEMA6A semaphorin 6A 2 2
MIRT495050 CTRC chymotrypsin C 2 4
MIRT500010 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501565 PLEKHF2 pleckstrin homology and FYVE domain containing 2 2 4
MIRT502680 CSNK1G3 casein kinase 1 gamma 3 2 8
MIRT503058 CAB39 calcium binding protein 39 2 2
MIRT504615 PLK1 polo like kinase 1 2 2
MIRT505706 SESN2 sestrin 2 2 2
MIRT506197 PHF19 PHD finger protein 19 2 2
MIRT506821 KIF23 kinesin family member 23 2 6
MIRT513782 PAWR pro-apoptotic WT1 regulator 2 6
MIRT527011 MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 2 4
MIRT527806 KLRD1 killer cell lectin like receptor D1 2 2
MIRT537896 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 4
MIRT537925 DST dystonin 2 2
MIRT540049 FOXC1 forkhead box C1 2 2
MIRT543395 DROSHA drosha ribonuclease III 2 2
MIRT545447 SC5D sterol-C5-desaturase 2 4
MIRT546876 RAB10 RAB10, member RAS oncogene family 2 4
MIRT549419 ACVR2B activin A receptor type 2B 2 2
MIRT551857 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT552453 ZNF410 zinc finger protein 410 2 2
MIRT552772 YIPF6 Yip1 domain family member 6 2 4
MIRT552788 YAF2 YY1 associated factor 2 2 2
MIRT554247 SLAIN2 SLAIN motif family member 2 2 2
MIRT554773 RHEBP1 RHEB pseudogene 1 2 4
MIRT555862 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT556475 LIPA lipase A, lysosomal acid type 2 2
MIRT556655 KMT2D lysine methyltransferase 2D 2 4
MIRT558210 EFCAB14 EF-hand calcium binding domain 14 2 4
MIRT558306 DUSP14 dual specificity phosphatase 14 2 2
MIRT558818 CDCA4 cell division cycle associated 4 2 4
MIRT559370 ATP13A3 ATPase 13A3 2 2
MIRT559541 ARGLU1 arginine and glutamate rich 1 2 4
MIRT563022 ZNF680 zinc finger protein 680 2 2
MIRT563036 NBPF12 NBPF member 12 2 2
MIRT563791 SLC28A1 solute carrier family 28 member 1 2 2
MIRT565903 SCAMP2 secretory carrier membrane protein 2 2 2
MIRT566957 LBR lamin B receptor 2 2
MIRT567971 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 2
MIRT570389 TSC22D2 TSC22 domain family member 2 2 2
MIRT575250 Timp3 tissue inhibitor of metalloproteinase 3 2 2
MIRT611519 ZNF25 zinc finger protein 25 2 2
MIRT611592 POTED POTE ankyrin domain family member D 2 2
MIRT614228 NPTXR neuronal pentraxin receptor 2 2
MIRT625933 SCYL3 SCY1 like pseudokinase 3 2 2
MIRT627320 TULP4 tubby like protein 4 2 2
MIRT631516 CTBS chitobiase 2 2
MIRT640705 MRS2 MRS2, magnesium transporter 2 2
MIRT642208 RUVBL2 RuvB like AAA ATPase 2 2 2
MIRT642767 FAM9C family with sequence similarity 9 member C 2 2
MIRT648411 KIAA0146 scaffolding protein involved in DNA repair 1 1
MIRT658045 FUT11 fucosyltransferase 11 2 2
MIRT663720 GLUL glutamate-ammonia ligase 2 2
MIRT698536 TFRC transferrin receptor 2 2
MIRT699988 RPS24 ribosomal protein S24 2 2
MIRT700433 PURB purine rich element binding protein B 2 2
MIRT705890 ADCY9 adenylate cyclase 9 2 2
MIRT706974 XPO5 exportin 5 2 2
MIRT710564 KIAA1958 KIAA1958 2 2
MIRT714070 RUNDC3B RUN domain containing 3B 2 2
MIRT716931 FAM13A family with sequence similarity 13 member A 2 2
MIRT717341 RAB40A RAB40A, member RAS oncogene family 2 2
MIRT717738 MYLK myosin light chain kinase 5 2
MIRT722963 SLC25A26 solute carrier family 25 member 26 2 2
MIRT723470 WIPF2 WAS/WASL interacting protein family member 2 2 2
MIRT732447 STAT3 signal transducer and activator of transcription 3 2 0
MIRT733631 SIRT1 sirtuin 1 3 0
MIRT733632 CCND1 cyclin D1 3 0
MIRT736012 RHEB Ras homolog, mTORC1 binding 3 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-1301 Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC-7901)
hsa-mir-1301 Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (BGC823)
hsa-mir-1301 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-1301 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-1301 Topotecan 60699 NSC609699 approved sensitive cell line (W1)
hsa-mir-1301 Androstenedione 6128 NSC9563 sensitive cell line (MCF-7)
hsa-mir-1301 Androstenedione+Letrozole sensitive cell line (MCF-7)
hsa-mir-1301 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-mir-1301 Cisplatin 5460033 NSC119875 approved resistant cell line (SGC-7901)
hsa-mir-1301 Cisplatin 5460033 NSC119875 approved resistant cell line (BGC-823)
hsa-miR-1301-3p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (RKO)
hsa-miR-1301-3p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (SW1990)
hsa-miR-1301-3p Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (SW1990)
hsa-miR-1301-3p Plx-4720 24180719 NSC757438 sensitive High Thyroid Cancer cell line (8505c, BCPAP)
hsa-miR-1301-3p Imatinib 5291 NSC743414 approved sensitive Low Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved sensitive High Pancreatic Cancer cell line (BxPC-3)
hsa-miR-1301-3p Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-1301-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer tissue
hsa-miR-1301-3p Fluorouracil 3385 NSC19893 approved resistant High Gastric Cancer tissue
hsa-miR-1301-3p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (M14) (2uM)
hsa-miR-1301-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (M14) (50nM)
hsa-miR-1301-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (M14) (2uM)
hsa-miR-1301-3p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (M14) (50nM)
hsa-miR-1301-3p Epirubicin 41867 NSC256942 approved sensitive Low Osteosarcoma cell line (U-2-OS, SAOS-2)
hsa-miR-1301-3p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (SGC-7901, BGC-823)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CP20)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-1301-3p Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (SW480, HCT-116)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved sensitive High Epithelial Ovarian Cancer cell line (SKOV3)
hsa-miR-1301-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-1301-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-1301-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-1301-3p Palbociclib 5330286 NSC758247 approved resistant tissue (breast cancer)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-1301-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-1301-3p Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-1301-3p 4-Hydroxytamoxifen+Tamoxifen sensitive cell line (LY2)
hsa-miR-1301-3p Ethanol+Tamoxifen sensitive cell line (LY2)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved resistant cell line (RPMI2650)
hsa-miR-1301-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

Error report submission