miRTarBase - #MIRT703252


—
pre-miRNA Information
pre-miRNA hsa-mir-4433a   
Genomic Coordinates chr2: 64340759 - 64340839
Description Homo sapiens miR-4433a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4433a-3p
Sequence 51| ACAGGAGUGGGGGUGGGACAU |71
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs751480515 9 dbSNP
rs557760377 15 dbSNP
rs1479580865 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol GNS   
Synonyms G6S
Description glucosamine (N-acetyl)-6-sulfatase
Transcript NM_002076   
Expression
Putative miRNA Targets on GNS
3'UTR of GNS
(miRNA target sites are highlighted)		 
>GNS|NM_002076|3'UTR
   1 CGACCTCACACAGCCTCTGCAGATGGATCCCTGCACGCCTCTTTCTGATGAAGTGATTGTAGTAGGTGTCTGTAGCTAGT
  81 CTTCAAGACCACACCTGGAAGAGTTTCTGGGCTGGCTTTAAGTCCTGTTTGAAAAAGCAACCCAGTCAGCTGACTTCCTC
 161 GTGCAATGTGTTAAACTGTGAACTCTGCCCATGTGTCAGGAGTGGCTGTCTCTGGTCTCTTCCTTTAGCTGACAAGGACA
 241 CTCCTGAGGTCTTTGTTCTCACTGTATTCTTTTTATCCTGGGGCCACAGTTCTTGATTATTCCTCTTGTGGTTAAAGACT
 321 GAATTTGTAAACCCATTCAGATAAATGGCAGTACTTTAGGACACACACAAACACACAGACACACCTTTTGATATGTAAGC
 401 TTGACCTAAAGTCAAAGGACCTGTGTAGCATTTCAGATTGAGCACTTCACTATCAAAAATACTAACATCACATGGCTTGA
 481 AGAGTAACCATCAGAGCTGAATCATCCAAGTAAGAACAAGTACCATTGTTGATTGATAAGTAGAGATACATTTTTTATGA
 561 TGTTCATCACAGTGTGGTAAGGTTGCAAATTCAAAACATGTCACCCAAGCTCTGTTCATGTTTTTGTGAATTCTAGGCTG
 641 GTGCTGCACTGAAATAGAGCAGTAAGCTTGTGATAAAGGCCAATTCCAGGTAGCTCTTGAAGGTGATAGCCATCTACTTT
 721 CCAGTGGCTGCCAACCACAGGGAGTGCCAGTTAACACTGGAAGGATTAAGGCAAGGTCCCTTCTCTTGAGACTCCCCTCT
 801 GAGATCTGAAAAATGAAGTGGCTTAGGAACATCAGCAGTGAAGAACTGCCAAGAGTTGGTGAAGGTTGTCTCTTCCGAGG
 881 GCCTTCTGAAGACAGGGCTCTTGAACAGACAAGTGGAAGGGCTGTACCAGGGATAAAGGAAAGAAGTGCCTGTCCAGCAG
 961 GGAGCTTGAATTTAAGTTCCATGTATGAAGTCATTGGCTCTATCTGCATTTTTCTGTCATTCTCTTCATTTGTTTTAAGG
1041 TGGAAAATTTTCTTACAGTTGATGCAAAGTATCAACTACTTTACCCTACCTTCTCCCCTTTTAGATGGGTTCTTCCTGAG
1121 TTTTGGAGTCTTGTATGATTATCAGTATTCCCCTGTCAAAATCAAATCTATTCAGGTTTCTTCACTGTTGAGAACACCTA
1201 AATGTTTTTATTTTTGAGAAGTGGGGACAGAGTCTCACTATGTCACCCAGGCTGGAGTGCAATGGCATGATCTCAGCTCA
1281 CTGCAACCTTCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCCGCCTCCTGAGTAGCTGGGATTATAGGCACGCACCACC
1361 ACGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACAGAGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTT
1441 GTGATCCACCCACCTCGGCCTCCCAGAGTGCTGGGATTACAGGCATGAGCCACCACGCTTGGCTAAGAACACCTAAATTT
1521 TTATGTTTCTTGGCTCAAAAACCAGTTCCATTTCTAATGTTGTCCTCACAAGAAGGCTAATTGGTGGTGAGACAGCAGGG
1601 GAGGAGGAAGAGCTGTGGTTTGTAACTTGTTCAACTCAGGCAATAAGCGATTTTAGCTTTATTTAAAGTCTTCTGTCCAG
1681 CTTTAAGCACTTTGTAAGACATGGCTGAAAGTAGCTTTTCTATCAGAATTGCAGATAGTCATGTTGGGCTAACAGTCAAT
1761 TGGATATATTCCTTTACCTCACATGACCCCAGCAACTGTGGTGGTATCTAGAGGTGAAACAGGCAAGTGAAATGGACACC
1841 TCTGCTGTGAATGTTTTAGAGAAGGAAATTCAAAAAATGTTGTAACTGAAAGCACTGTTGAATATGGGTATCGGCTTTCT
1921 TTTTCACTTTGACTCTTAACATTATCAGTCAACTTCCACATTAATGAAAGTTGACCATAGTTATTTCCAAATAAAAAGAA
2001 ACCAACTCTTACCAGGTCTTGGACTGTGATGTCATATTATTCAGTTTTATGCTTGTTCCTGAGCAGAACTCATAAGAGTG
2081 ACATAGTCAGCTGCTGACGGCACCTCAGCCACGCCACTCTTACTCAGTTCAGTGGGTGTGCTTGCGTGGTAGGATGTGGT
2161 GCAGCCCTCTCTACGCTCTTCTATTTTTGGTATATTTCCTATCTAACCTTCAAATAGCTTCCAATTCTTTTTTTCTTGGA
2241 CTGGCTTCATTCTGAATTTGTGCTAAAATAATCTTTCATAAAGAGACCTCAGTTTATAGCGTAACAGACTACACAATGCA
2321 CTGATGTTTTCATAATGTTTAAGGGACCCACTGCAAGAAGCTTGCTGCCTCCTTTTAATTGTATTCATTTAGATTTTGAT
2401 TTTCCATGTTAAGAAGGTGAGGTCCATGTTGGTGCCCTTCAGAGTAGAGAACCATGTAAACATTAGGAATGAACAGAGGC
2481 CTTAGGAATGAATAGAGAGTTTGCCTTATACAATTTCCTGTTACAAAGCTCTCCCTCTCATGCAAAGTAGGGAACACCTT
2561 TTGAGCATCTTTGAATTTGACAAATGGTGCTGTTGCAAACACTTTTTTTTTGAGATGAAGTCTCGCGGTTGTCACCCGGG
2641 CTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACTTCCACCTCCTGGGTTCCAGCAGTTCTCCTGCCTCAGCCTCCCA
2721 AGTAGCTGAGATTACAGGCGCCTGCCACCCCACCTGGCTGATTTTTGTAATTTTAGTAGAGACGGGGTTTCACCATGTTG
2801 GCCAGGCTGATTAACTCCTGACCTCAGGTGATCCACCTTTCTCGGCCTCCCAAAGTGCTGGGATTACGGGTGTGAGCCAC
2881 CGTGCCCGGCCTGCAAACACATTTTAATTGACAACACTAGGGCTGTTGTACAAAATAGTAATGATAGCCATGGAAGTTTT
2961 ACCTTATTCTGTGAGAAGTGTTCTTAAACTTATTAAGTGTCTAAACTAAGGTTTAGTGCTTTTTTAAAGGAAAGTTGTCC
3041 CAGGATTCATCCTAAAGAAAGCAAAAGTTAATTCAACTGATCCACCAATGGAATTAGATGGGTAGAGTTGGGTTCTTGAG
3121 TTTTACCACCACTTAGTTCCCACTGAATTTTGTAACTTCCTGTGTTTGCATCCTCTGTTCCTATTCTGCCCTTGCTCTGT
3201 GTCATCTCAGTCATTTGACTTAGAAAGTGCCCTTCAAAAGGACCCTGTTCACTGCTGCACTTTTCAATGAATTAAAATTT
3281 ATTTCTGTTCTAGTGGGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uacaggguggggGUGAGGACa 5'
                      |||||||| 
Target 5' agctgacaaggaCACTCCTGa 3'
 227 - 247 145.00 -16.60
2 
miRNA  3' uaCAGGGUGGGG-GUGAGGACa 5'
            | |: ::|::  ||||||| 
Target 5' caGGCTGGTCTTGAACTCCTGa 3'
 1415 - 1436 143.00 -15.50
3 
miRNA  3' uaCAG--GGU--GG--GGGUGAGGACa 5'
            ||:  |||  |:  :: ||||||| 
Target 5' atGTTGGCCAGGCTGATTAACTCCTGa 3'
 2795 - 2821 141.00 -13.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
990668 4 ClinVar
310204 37 ClinVar
881006 71 ClinVar
883372 86 ClinVar
310203 152 ClinVar
310202 269 ClinVar
310201 319 ClinVar
310200 334 ClinVar
310199 357 ClinVar
310198 380 ClinVar
310197 411 ClinVar
310196 425 ClinVar
310195 566 ClinVar
310194 574 ClinVar
310193 599 ClinVar
310192 676 ClinVar
882584 699 ClinVar
310191 734 ClinVar
310190 764 ClinVar
882316 814 ClinVar
310189 826 ClinVar
310188 846 ClinVar
310187 942 ClinVar
310186 985 ClinVar
310185 1228 ClinVar
310184 1353 ClinVar
880957 1435 ClinVar
310183 1456 ClinVar
310182 1580 ClinVar
310181 1648 ClinVar
310180 1681 ClinVar
310179 1759 ClinVar
880956 1809 ClinVar
310178 1862 ClinVar
880955 1977 ClinVar
310177 1990 ClinVar
310176 2032 ClinVar
883320 2099 ClinVar
883319 2146 ClinVar
883318 2278 ClinVar
883317 2301 ClinVar
310175 2361 ClinVar
882537 2406 ClinVar
310174 2447 ClinVar
882536 2489 ClinVar
310173 2560 ClinVar
882535 2571 ClinVar
310172 2612 ClinVar
882534 2612 ClinVar
882533 2625 ClinVar
310171 2656 ClinVar
310170 2699 ClinVar
310169 2735 ClinVar
310168 2740 ClinVar
310167 2751 ClinVar
310166 2783 ClinVar
310165 2788 ClinVar
310164 2843 ClinVar
882267 2844 ClinVar
310163 3070 ClinVar
COSN30504359 1 COSMIC
COSN30521377 13 COSMIC
COSN30495278 29 COSMIC
COSN31509940 30 COSMIC
COSN31514937 36 COSMIC
COSN30158850 41 COSMIC
COSN31488211 47 COSMIC
COSN30497850 52 COSMIC
COSN30568725 132 COSMIC
COSN5949676 470 COSMIC
COSN15768535 815 COSMIC
COSN32058779 942 COSMIC
COSN29457598 1005 COSMIC
COSN28188315 1119 COSMIC
COSN20335271 1427 COSMIC
COSN26552291 1793 COSMIC
COSN31542834 1814 COSMIC
COSN15660873 2031 COSMIC
COSN20092599 2447 COSMIC
COSN21467190 2961 COSMIC
COSN31577569 3139 COSMIC
COSN31489478 3208 COSMIC
COSN24845304 3213 COSMIC
COSN31528839 3278 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs113381844 1 dbSNP
rs145017402 2 dbSNP
rs766104697 4 dbSNP
rs765412748 10 dbSNP
rs369482033 11 dbSNP
rs1187728803 19 dbSNP
rs768718890 20 dbSNP
rs1242431628 23 dbSNP
rs1181742350 24 dbSNP
rs760916879 25 dbSNP
rs775194425 28 dbSNP
rs1203577567 29 dbSNP
rs1305945261 32 dbSNP
rs771883330 35 dbSNP
rs745869300 36 dbSNP
rs142001509 37 dbSNP
rs1313547082 38 dbSNP
rs1454984212 41 dbSNP
rs1380541134 43 dbSNP
rs1297911111 50 dbSNP
rs762354606 55 dbSNP
rs182626038 59 dbSNP
rs1372868061 68 dbSNP
rs983471422 71 dbSNP
rs1012342438 72 dbSNP
rs952222783 74 dbSNP
rs1383941805 89 dbSNP
rs1245942386 92 dbSNP
rs1311184206 115 dbSNP
rs1027771161 117 dbSNP
rs1319465798 118 dbSNP
rs991380939 127 dbSNP
rs540848251 133 dbSNP
rs1410494182 140 dbSNP
rs1251312459 151 dbSNP
rs768957003 152 dbSNP
rs1035169031 160 dbSNP
rs190758540 161 dbSNP
rs1000014569 175 dbSNP
rs1244776997 176 dbSNP
rs1412224978 191 dbSNP
rs902780529 191 dbSNP
rs902547164 196 dbSNP
rs1020331648 203 dbSNP
rs147744724 219 dbSNP
rs997444056 220 dbSNP
rs1464292197 221 dbSNP
rs1009944643 231 dbSNP
rs1407364902 235 dbSNP
rs147121750 240 dbSNP
rs186861385 241 dbSNP
rs1206990614 250 dbSNP
rs556274387 253 dbSNP
rs536602674 260 dbSNP
rs2279597 269 dbSNP
rs1215605868 270 dbSNP
rs909025207 272 dbSNP
rs1216452594 275 dbSNP
rs1316700447 275 dbSNP
rs1264591948 283 dbSNP
rs1241239648 288 dbSNP
rs1209158329 291 dbSNP
rs1235454823 294 dbSNP
rs375796330 299 dbSNP
rs1486819915 307 dbSNP
rs368523842 319 dbSNP
rs111768263 332 dbSNP
rs886049771 334 dbSNP
rs1178927596 335 dbSNP
rs554471490 357 dbSNP
rs929016840 365 dbSNP
rs1332619838 370 dbSNP
rs928325285 370 dbSNP
rs1040246649 376 dbSNP
rs674 380 dbSNP
rs1338298520 384 dbSNP
rs11175525 411 dbSNP
rs1397574803 415 dbSNP
rs1323813718 420 dbSNP
rs1218227966 421 dbSNP
rs916860880 424 dbSNP
rs141736156 425 dbSNP
rs745596433 428 dbSNP
rs538347868 435 dbSNP
rs771855325 445 dbSNP
rs1262374362 447 dbSNP
rs930688129 452 dbSNP
rs920656556 454 dbSNP
rs745654395 459 dbSNP
rs1288986173 465 dbSNP
rs990895626 472 dbSNP
rs569690247 475 dbSNP
rs778459851 486 dbSNP
rs778911538 500 dbSNP
rs1170993677 506 dbSNP
rs11553424 514 dbSNP
rs958239914 524 dbSNP
rs928102249 527 dbSNP
rs1401626237 529 dbSNP
rs1159087658 543 dbSNP
rs1032914971 560 dbSNP
rs1427032499 565 dbSNP
rs17100604 566 dbSNP
rs1345551658 568 dbSNP
rs886049770 574 dbSNP
rs1435361052 582 dbSNP
rs1272692229 588 dbSNP
rs1021241740 591 dbSNP
rs151304792 599 dbSNP
rs1284957648 601 dbSNP
rs1351433141 613 dbSNP
rs1224572810 614 dbSNP
rs1387549736 617 dbSNP
rs1030349907 633 dbSNP
rs1234805540 635 dbSNP
rs957086433 641 dbSNP
rs1470756299 642 dbSNP
rs1187055858 643 dbSNP
rs997487548 648 dbSNP
rs190476647 653 dbSNP
rs1017553682 655 dbSNP
rs547272836 666 dbSNP
rs900263686 668 dbSNP
rs1404226832 671 dbSNP
rs1321250126 675 dbSNP
rs886049769 676 dbSNP
rs1487517506 678 dbSNP
rs1308283018 687 dbSNP
rs1374336306 690 dbSNP
rs1047983882 692 dbSNP
rs929090925 693 dbSNP
rs1008768111 695 dbSNP
rs886340318 697 dbSNP
rs1208133011 703 dbSNP
rs1263624633 710 dbSNP
rs1438623526 717 dbSNP
rs542250805 718 dbSNP
rs1198193682 721 dbSNP
rs1047661826 722 dbSNP
rs1446798843 725 dbSNP
rs1045472748 732 dbSNP
rs886049768 734 dbSNP
rs948413130 756 dbSNP
rs930573112 757 dbSNP
rs886049767 764 dbSNP
rs991065483 770 dbSNP
rs1330235939 794 dbSNP
rs1364047801 799 dbSNP
rs1295787824 813 dbSNP
rs78614043 814 dbSNP
rs1055055638 818 dbSNP
rs1339811721 821 dbSNP
rs886049766 826 dbSNP
rs938058230 829 dbSNP
rs1364800471 833 dbSNP
rs978641287 837 dbSNP
rs886049765 846 dbSNP
rs573579525 848 dbSNP
rs185972636 859 dbSNP
rs982237796 865 dbSNP
rs1256383196 875 dbSNP
rs1462985784 876 dbSNP
rs1204712725 879 dbSNP
rs966934400 880 dbSNP
rs1255834566 882 dbSNP
rs1441211328 888 dbSNP
rs1195900637 900 dbSNP
rs1425916492 901 dbSNP
rs1374341548 902 dbSNP
rs753856404 909 dbSNP
rs914122909 921 dbSNP
rs1477851435 931 dbSNP
rs1169597142 936 dbSNP
rs12309081 942 dbSNP
rs755039590 946 dbSNP
rs76770087 952 dbSNP
rs964743947 956 dbSNP
rs1167140021 958 dbSNP
rs958547204 962 dbSNP
rs1017585130 967 dbSNP
rs1032647708 969 dbSNP
rs1006147463 983 dbSNP
rs531715804 985 dbSNP
rs1327159608 995 dbSNP
rs866235544 997 dbSNP
rs1026162140 1000 dbSNP
rs964447043 1002 dbSNP
rs907018808 1014 dbSNP
rs1045496510 1021 dbSNP
rs1373877243 1022 dbSNP
rs1018732493 1026 dbSNP
rs368854235 1027 dbSNP
rs1207464654 1030 dbSNP
rs1263033038 1037 dbSNP
rs1488371495 1046 dbSNP
rs1203003601 1047 dbSNP
rs142318610 1056 dbSNP
rs1481226980 1058 dbSNP
rs894153311 1062 dbSNP
rs533954740 1065 dbSNP
rs1490507348 1066 dbSNP
rs1464343934 1067 dbSNP
rs1160294565 1069 dbSNP
rs148745277 1071 dbSNP
rs994729754 1079 dbSNP
rs899080673 1081 dbSNP
rs1055046325 1085 dbSNP
rs1202791963 1088 dbSNP
rs938048454 1089 dbSNP
rs923459322 1090 dbSNP
rs928040337 1095 dbSNP
rs1241623416 1096 dbSNP
rs1261616782 1097 dbSNP
rs1341128122 1097 dbSNP
rs1353640807 1097 dbSNP
rs1046490604 1106 dbSNP
rs945472011 1109 dbSNP
rs1215027488 1135 dbSNP
rs914046007 1139 dbSNP
rs990064445 1141 dbSNP
rs751608125 1144 dbSNP
rs1490688651 1153 dbSNP
rs936900964 1163 dbSNP
rs1322886250 1168 dbSNP
rs921545134 1171 dbSNP
rs766578909 1172 dbSNP
rs964395598 1176 dbSNP
rs554534769 1189 dbSNP
rs1183738014 1190 dbSNP
rs964753693 1200 dbSNP
rs540926785 1201 dbSNP
rs984763118 1216 dbSNP
rs763216125 1221 dbSNP
rs952067941 1224 dbSNP
rs1026674643 1225 dbSNP
rs950526749 1226 dbSNP
rs1393303516 1227 dbSNP
rs115625510 1228 dbSNP
rs750761593 1229 dbSNP
rs995118590 1230 dbSNP
rs1024058177 1240 dbSNP
rs1317761050 1245 dbSNP
rs1377261647 1246 dbSNP
rs1271733 1254 dbSNP
rs899074538 1258 dbSNP
rs1177284696 1262 dbSNP
rs1033586386 1266 dbSNP
rs1481431676 1267 dbSNP
rs1270981036 1268 dbSNP
rs765628711 1269 dbSNP
rs558081278 1272 dbSNP
rs1270835 1275 dbSNP
rs538386811 1276 dbSNP
rs1197137258 1279 dbSNP
rs1238599578 1285 dbSNP
rs1002143227 1290 dbSNP
rs906521905 1291 dbSNP
rs556576707 1292 dbSNP
rs1437161357 1299 dbSNP
rs1046396385 1301 dbSNP
rs1387014243 1308 dbSNP
rs945448665 1309 dbSNP
rs894204135 1313 dbSNP
rs1251050581 1315 dbSNP
rs1366743484 1320 dbSNP
rs1463752205 1322 dbSNP
rs1054062471 1323 dbSNP
rs569671194 1324 dbSNP
rs1255007809 1325 dbSNP
rs1053948293 1327 dbSNP
rs1339029644 1331 dbSNP
rs936862269 1333 dbSNP
rs921495870 1341 dbSNP
rs1319367943 1344 dbSNP
rs1220137413 1348 dbSNP
rs1258285418 1351 dbSNP
rs975637241 1352 dbSNP
rs1269548 1353 dbSNP
rs1228391278 1354 dbSNP
rs911524960 1354 dbSNP
rs1430362037 1355 dbSNP
rs1336855426 1361 dbSNP
rs535876857 1362 dbSNP
rs1179058513 1363 dbSNP
rs566900078 1371 dbSNP
rs950493659 1373 dbSNP
rs1040542972 1379 dbSNP
rs1026517636 1388 dbSNP
rs1301576326 1391 dbSNP
rs1376408532 1397 dbSNP
rs1278206880 1398 dbSNP
rs1316938671 1400 dbSNP
rs1216363707 1405 dbSNP
rs1280511178 1406 dbSNP
rs1401795742 1415 dbSNP
rs943449078 1419 dbSNP
rs1209396080 1427 dbSNP
rs1337572974 1431 dbSNP
rs547333907 1435 dbSNP
rs973248584 1437 dbSNP
rs1194494836 1445 dbSNP
rs963207218 1446 dbSNP
rs1262502347 1453 dbSNP
rs1476981504 1455 dbSNP
rs144199387 1456 dbSNP
rs1002049878 1457 dbSNP
rs906469651 1468 dbSNP
rs1158508086 1470 dbSNP
rs952182706 1471 dbSNP
rs1420783203 1480 dbSNP
rs1298307743 1486 dbSNP
rs146025372 1487 dbSNP
rs1364283957 1491 dbSNP
rs1010024992 1497 dbSNP
rs892536846 1503 dbSNP
rs551308742 1513 dbSNP
rs1054301221 1516 dbSNP
rs15692 1532 dbSNP
rs531500203 1548 dbSNP
rs899971100 1549 dbSNP
rs11553423 1556 dbSNP
rs1368111436 1558 dbSNP
rs1218432235 1560 dbSNP
rs1242163249 1564 dbSNP
rs1355793248 1576 dbSNP
rs886049764 1580 dbSNP
rs1217196853 1581 dbSNP
rs1203839158 1584 dbSNP
rs1285446132 1597 dbSNP
rs1487335454 1602 dbSNP
rs1224124823 1603 dbSNP
rs1247501173 1604 dbSNP
rs1462375667 1609 dbSNP
rs562877590 1615 dbSNP
rs1265760297 1618 dbSNP
rs777147046 1620 dbSNP
rs1440884789 1621 dbSNP
rs1352088038 1622 dbSNP
rs769056238 1629 dbSNP
rs1359399805 1635 dbSNP
rs912857405 1643 dbSNP
rs1417307399 1646 dbSNP
rs75568735 1648 dbSNP
rs1350120414 1649 dbSNP
rs758411763 1654 dbSNP
rs1012674015 1658 dbSNP
rs1272888642 1660 dbSNP
rs1340174982 1680 dbSNP
rs142676698 1681 dbSNP
rs1454832173 1687 dbSNP
rs918996312 1697 dbSNP
rs1308423234 1699 dbSNP
rs1386695372 1701 dbSNP
rs973538718 1707 dbSNP
rs1230102907 1712 dbSNP
rs1320016742 1722 dbSNP
rs1401313101 1728 dbSNP
rs1451277080 1737 dbSNP
rs999943642 1738 dbSNP
rs560488697 1740 dbSNP
rs1240458906 1750 dbSNP
rs540594590 1759 dbSNP
rs1178629191 1777 dbSNP
rs926426344 1784 dbSNP
rs1379000550 1791 dbSNP
rs1474025944 1801 dbSNP
rs1164515814 1804 dbSNP
rs980577225 1814 dbSNP
rs1404437346 1816 dbSNP
rs1321148259 1825 dbSNP
rs1402261808 1831 dbSNP
rs139132035 1837 dbSNP
rs1330346397 1844 dbSNP
rs1374591973 1847 dbSNP
rs1025338051 1849 dbSNP
rs1450072637 1852 dbSNP
rs1009549926 1854 dbSNP
rs956895312 1858 dbSNP
rs201406329 1861 dbSNP
rs3832839 1862 dbSNP
rs3741746 1863 dbSNP
rs1226870255 1870 dbSNP
rs1245786340 1871 dbSNP
rs1260221068 1878 dbSNP
rs1319119341 1881 dbSNP
rs558399351 1883 dbSNP
rs1447019535 1884 dbSNP
rs1236677809 1889 dbSNP
rs1040638355 1897 dbSNP
rs1032355059 1898 dbSNP
rs1000916647 1902 dbSNP
rs1359330028 1912 dbSNP
rs1293016970 1913 dbSNP
rs544492518 1918 dbSNP
rs899920283 1935 dbSNP
rs1465764696 1936 dbSNP
rs1169728378 1939 dbSNP
rs1394021266 1941 dbSNP
rs1049645835 1944 dbSNP
rs1363322288 1946 dbSNP
rs1334717351 1948 dbSNP
rs1340007705 1950 dbSNP
rs1445909787 1955 dbSNP
rs1280102427 1956 dbSNP
rs1297084478 1956 dbSNP
rs549425941 1962 dbSNP
rs1218203659 1964 dbSNP
rs1008434487 1966 dbSNP
rs1321667932 1967 dbSNP
rs1201584706 1970 dbSNP
rs1403593888 1971 dbSNP
rs1364865715 1975 dbSNP
rs1441120857 1976 dbSNP
rs972066101 1979 dbSNP
rs971733077 1981 dbSNP
rs1477962857 1983 dbSNP
rs17100600 1990 dbSNP
rs538753671 1993 dbSNP
rs556012717 1998 dbSNP
rs1371180590 2000 dbSNP
rs529982367 2002 dbSNP
rs1185507305 2003 dbSNP
rs1401419146 2005 dbSNP
rs1432724790 2006 dbSNP
rs1300149742 2008 dbSNP
rs1475534321 2012 dbSNP
rs1361209684 2013 dbSNP
rs545878280 2021 dbSNP
rs1196098475 2023 dbSNP
rs1490340382 2026 dbSNP
rs930262649 2027 dbSNP
rs1333255431 2030 dbSNP
rs886049763 2032 dbSNP
rs1274568343 2035 dbSNP
rs1343517320 2039 dbSNP
rs1219387179 2040 dbSNP
rs1287594649 2042 dbSNP
rs566964017 2047 dbSNP
rs1379429513 2072 dbSNP
rs978924418 2073 dbSNP
rs967132222 2086 dbSNP
rs1434476788 2089 dbSNP
rs941748050 2098 dbSNP
rs553360517 2099 dbSNP
rs1452545440 2106 dbSNP
rs1160359151 2112 dbSNP
rs980567416 2113 dbSNP
rs1272571145 2123 dbSNP
rs970566738 2124 dbSNP
rs1323350816 2127 dbSNP
rs1341722598 2132 dbSNP
rs533516870 2136 dbSNP
rs150772287 2142 dbSNP
rs570203117 2143 dbSNP
rs1353881568 2145 dbSNP
rs900823217 2146 dbSNP
rs1489271974 2149 dbSNP
rs1210030980 2152 dbSNP
rs917772899 2165 dbSNP
rs571468415 2172 dbSNP
rs988442450 2173 dbSNP
rs1180505097 2174 dbSNP
rs369653063 2175 dbSNP
rs1303637584 2178 dbSNP
rs1157037141 2188 dbSNP
rs551638399 2189 dbSNP
rs1368547360 2192 dbSNP
rs1458643103 2197 dbSNP
rs1169468641 2199 dbSNP
rs1162871074 2202 dbSNP
rs1410230119 2206 dbSNP
rs1449465930 2213 dbSNP
rs1049191307 2223 dbSNP
rs1376832550 2224 dbSNP
rs1421160330 2236 dbSNP
rs930740068 2249 dbSNP
rs1000903432 2252 dbSNP
rs1304281267 2258 dbSNP
rs1322974597 2260 dbSNP
rs897879142 2266 dbSNP
rs1036841344 2278 dbSNP
rs950078336 2282 dbSNP
rs1200317053 2283 dbSNP
rs778825291 2296 dbSNP
rs1238507876 2297 dbSNP
rs745566534 2300 dbSNP
rs141182054 2301 dbSNP
rs1424464273 2304 dbSNP
rs1164433234 2309 dbSNP
rs1415962365 2313 dbSNP
rs1008387023 2316 dbSNP
rs891259951 2321 dbSNP
rs1171858988 2324 dbSNP
rs1047243472 2329 dbSNP
rs1399975485 2331 dbSNP
rs1202145812 2332 dbSNP
rs550181590 2333 dbSNP
rs1396111160 2356 dbSNP
rs1061743 2361 dbSNP
rs978591209 2385 dbSNP
rs1258509564 2391 dbSNP
rs967604236 2391 dbSNP
rs898753822 2396 dbSNP
rs549541581 2404 dbSNP
rs1037319060 2407 dbSNP
rs941737503 2422 dbSNP
rs1181368257 2427 dbSNP
rs1255431121 2443 dbSNP
rs1205637925 2444 dbSNP
rs567930294 2447 dbSNP
rs904941118 2448 dbSNP
rs976908243 2454 dbSNP
rs1439819012 2461 dbSNP
rs1423423126 2463 dbSNP
rs1427104656 2472 dbSNP
rs1178599986 2480 dbSNP
rs529418480 2489 dbSNP
rs1276718917 2493 dbSNP
rs965076343 2497 dbSNP
rs1311776899 2499 dbSNP
rs1373061831 2500 dbSNP
rs1223007999 2501 dbSNP
rs1350957779 2505 dbSNP
rs1017920778 2507 dbSNP
rs1278429415 2507 dbSNP
rs1324286703 2508 dbSNP
rs1044766506 2511 dbSNP
rs1007819273 2513 dbSNP
rs1167583720 2518 dbSNP
rs889348909 2524 dbSNP
rs1217706803 2526 dbSNP
rs1225334640 2535 dbSNP
rs148217767 2538 dbSNP
rs1028250406 2542 dbSNP
rs886049762 2560 dbSNP
rs1193304369 2569 dbSNP
rs995044057 2571 dbSNP
rs1433152801 2589 dbSNP
rs949157944 2592 dbSNP
rs1355937903 2601 dbSNP
rs547034900 2602 dbSNP
rs201933913 2612 dbSNP
rs533328232 2612 dbSNP
rs1295102384 2618 dbSNP
rs73323439 2624 dbSNP
rs1468841522 2625 dbSNP
rs1036485392 2626 dbSNP
rs1429465882 2627 dbSNP
rs935238610 2628 dbSNP
rs1177955269 2632 dbSNP
rs1471926185 2633 dbSNP
rs1407857430 2637 dbSNP
rs145906720 2638 dbSNP
rs1224006421 2650 dbSNP
rs1178173595 2655 dbSNP
rs577212739 2656 dbSNP
rs770812812 2663 dbSNP
rs1235960696 2664 dbSNP
rs749062392 2666 dbSNP
rs979409758 2668 dbSNP
rs1192380314 2669 dbSNP
rs950126830 2679 dbSNP
rs1440788075 2680 dbSNP
rs1158752526 2683 dbSNP
rs1406563431 2686 dbSNP
rs895827504 2690 dbSNP
rs1350318331 2698 dbSNP
rs867153534 2699 dbSNP
rs547788908 2704 dbSNP
rs1461931244 2706 dbSNP
rs1379046762 2707 dbSNP
rs1447371724 2710 dbSNP
rs554197342 2713 dbSNP
rs1279077218 2719 dbSNP
rs1018300414 2721 dbSNP
rs1265132088 2728 dbSNP
rs143396704 2735 dbSNP
rs955486433 2739 dbSNP
rs886049761 2740 dbSNP
rs1260342720 2748 dbSNP
rs137943279 2751 dbSNP
rs994378631 2763 dbSNP
rs945943039 2777 dbSNP
rs573404754 2783 dbSNP
rs898738577 2784 dbSNP
rs976506035 2786 dbSNP
rs886049760 2788 dbSNP
rs1375175199 2793 dbSNP
rs751642036 2794 dbSNP
rs1451543644 2805 dbSNP
rs188119987 2809 dbSNP
rs1328084516 2814 dbSNP
rs1334129430 2820 dbSNP
rs1338182406 2820 dbSNP
rs1450949401 2833 dbSNP
rs1345141185 2836 dbSNP
rs1284796613 2837 dbSNP
rs1160395712 2838 dbSNP
rs1231647409 2839 dbSNP
rs1260443718 2840 dbSNP
rs147105773 2841 dbSNP
rs577545481 2843 dbSNP
rs534118009 2844 dbSNP
rs1445512017 2851 dbSNP
rs1027929587 2853 dbSNP
rs538136456 2867 dbSNP
rs1052696851 2868 dbSNP
rs1185316268 2871 dbSNP
rs750602693 2881 dbSNP
rs925179626 2882 dbSNP
rs962269307 2883 dbSNP
rs149013255 2887 dbSNP
rs942611699 2888 dbSNP
rs549205368 2889 dbSNP
rs1313594137 2898 dbSNP
rs535614611 2911 dbSNP
rs566983291 2914 dbSNP
rs955633450 2931 dbSNP
rs1025764737 2936 dbSNP
rs1289388858 2939 dbSNP
rs184110950 2944 dbSNP
rs1001515080 2945 dbSNP
rs1220286026 2948 dbSNP
rs767618187 2948 dbSNP
rs1280481769 2950 dbSNP
rs962884290 2956 dbSNP
rs1017077949 2959 dbSNP
rs1208362515 2961 dbSNP
rs904522705 2971 dbSNP
rs1447161933 2989 dbSNP
rs11553427 2992 dbSNP
rs145797587 2993 dbSNP
rs1371088261 2996 dbSNP
rs945920603 3010 dbSNP
rs913068025 3011 dbSNP
rs1316657336 3020 dbSNP
rs1040877966 3026 dbSNP
rs11553428 3030 dbSNP
rs1300048878 3042 dbSNP
rs761900545 3044 dbSNP
rs1316727802 3047 dbSNP
rs1333169376 3060 dbSNP
rs1380042353 3061 dbSNP
rs1234677930 3063 dbSNP
rs1360583914 3070 dbSNP
rs397946778 3070 dbSNP
rs1346257960 3078 dbSNP
rs911002612 3082 dbSNP
rs1231458594 3088 dbSNP
rs906135267 3091 dbSNP
rs375707162 3096 dbSNP
rs1350986334 3101 dbSNP
rs1023251251 3112 dbSNP
rs952451644 3128 dbSNP
rs1259463740 3129 dbSNP
rs1453105072 3154 dbSNP
rs1194261780 3156 dbSNP
rs919575309 3159 dbSNP
rs751529481 3160 dbSNP
rs1160561546 3163 dbSNP
rs1364420851 3170 dbSNP
rs896206621 3171 dbSNP
rs1453378981 3186 dbSNP
rs1364218118 3188 dbSNP
rs751684429 3197 dbSNP
rs973687079 3201 dbSNP
rs1425633937 3203 dbSNP
rs962566090 3208 dbSNP
rs1369461518 3213 dbSNP
rs1449603666 3229 dbSNP
rs1308567618 3232 dbSNP
rs1335813575 3240 dbSNP
rs1052219740 3250 dbSNP
rs999695359 3267 dbSNP
rs764659197 3270 dbSNP
rs1014405304 3279 dbSNP
rs1428142326 3280 dbSNP
rs1272265747 3281 dbSNP
rs903664067 3285 dbSNP
rs1467111445 3290 dbSNP
rs1262594352 3293 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uacAGGGUGGGGG-UGAGGACa 5'
             |||::||:||  |||||| 
Target 5' uucUCCUGCCUCCGCCUCCUGa 3'
 		9 - 30
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000418919.2 | 3UTR | UCAAGCGAUUCUCCUGCCUCCGCCUCCUGAGUAGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
256 hsa-miR-4433a-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT088097 SEPT2 septin 2 2 2
MIRT143134 MGRN1 mahogunin ring finger 1 2 2
MIRT153912 NCOA3 nuclear receptor coactivator 3 2 2
MIRT154894 GNAS GNAS complex locus 2 4
MIRT200996 ZNF805 zinc finger protein 805 2 2
MIRT215729 C5ORF51 chromosome 5 open reading frame 51 2 10
MIRT235593 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT263250 SGPL1 sphingosine-1-phosphate lyase 1 2 2
MIRT317951 CDC5L cell division cycle 5 like 2 4
MIRT325572 HIATL1 major facilitator superfamily domain containing 14B 2 4
MIRT354739 LSM3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated 2 2
MIRT444552 UBE2D3 ubiquitin conjugating enzyme E2 D3 2 4
MIRT446978 SUSD5 sushi domain containing 5 2 2
MIRT451036 ZNF610 zinc finger protein 610 2 2
MIRT451596 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT452025 NLRP6 NLR family pyrin domain containing 6 2 2
MIRT452594 CA6 carbonic anhydrase 6 2 2
MIRT452768 TCEA3 transcription elongation factor A3 2 4
MIRT452959 ZNF844 zinc finger protein 844 2 2
MIRT453191 ACSF2 acyl-CoA synthetase family member 2 2 2
MIRT453382 RHD Rh blood group D antigen 2 2
MIRT453685 CEBPD CCAAT/enhancer binding protein delta 2 2
MIRT455272 DDX39B DExD-box helicase 39B 2 8
MIRT455346 BAMBI BMP and activin membrane bound inhibitor 2 2
MIRT456494 SERAC1 serine active site containing 1 2 2
MIRT456585 NID1 nidogen 1 2 2
MIRT456888 DDA1 DET1 and DDB1 associated 1 2 2
MIRT457123 APOLD1 apolipoprotein L domain containing 1 2 2
MIRT457852 ZNF324B zinc finger protein 324B 2 2
MIRT457987 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT459278 APOBEC3F apolipoprotein B mRNA editing enzyme catalytic subunit 3F 2 2
MIRT459625 SLC25A33 solute carrier family 25 member 33 2 2
MIRT459715 SGK494 uncharacterized serine/threonine-protein kinase SgK494 2 2
MIRT460057 RPL22L1 ribosomal protein L22 like 1 2 2
MIRT460182 UNK unkempt family zinc finger 2 6
MIRT460288 PDE11A phosphodiesterase 11A 2 2
MIRT460841 EGF epidermal growth factor 2 4
MIRT460860 TBC1D19 TBC1 domain family member 19 2 2
MIRT461519 EMC7 ER membrane protein complex subunit 7 2 2
MIRT461729 SLC27A1 solute carrier family 27 member 1 2 4
MIRT461821 SNAP23 synaptosome associated protein 23 2 2
MIRT462066 CCDC77 coiled-coil domain containing 77 2 4
MIRT462084 MSANTD2 Myb/SANT DNA binding domain containing 2 2 2
MIRT462508 MTFMT mitochondrial methionyl-tRNA formyltransferase 2 10
MIRT464239 VCP valosin containing protein 2 2
MIRT465316 TRAF5 TNF receptor associated factor 5 2 2
MIRT466549 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT467128 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 2 8
MIRT468091 SHCBP1 SHC binding and spindle associated 1 2 2
MIRT469630 RAD21 RAD21 cohesin complex component 2 6
MIRT471097 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 2 2
MIRT472704 MYBL1 MYB proto-oncogene like 1 2 2
MIRT472830 MTMR10 myotubularin related protein 10 2 2
MIRT472872 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT472895 MTDH metadherin 2 2
MIRT473728 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT473859 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT474047 LONRF1 LON peptidase N-terminal domain and ring finger 1 2 2
MIRT474297 LAMC1 laminin subunit gamma 1 2 2
MIRT474658 KLF13 Kruppel like factor 13 2 2
MIRT475234 IKZF3 IKAROS family zinc finger 3 2 2
MIRT475500 HSP90B1 heat shock protein 90 beta family member 1 2 2
MIRT475742 HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 2 4
MIRT475793 HDGF heparin binding growth factor 2 2
MIRT477254 ERGIC2 ERGIC and golgi 2 2 2
MIRT478228 DDX52 DExD-box helicase 52 2 2
MIRT478393 DCTN5 dynactin subunit 5 2 2
MIRT478754 CS citrate synthase 2 2
MIRT478827 CRKL CRK like proto-oncogene, adaptor protein 2 4
MIRT480234 C9orf41 carnosine N-methyltransferase 1 2 2
MIRT480597 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2 2
MIRT484121 C14orf142 GON7, KEOPS complex subunit homolog 2 2
MIRT484689 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2 2
MIRT486331 C11orf54 chromosome 11 open reading frame 54 2 4
MIRT488599 FAM3C family with sequence similarity 3 member C 2 8
MIRT488833 MRRF mitochondrial ribosome recycling factor 2 2
MIRT492523 RAB15 RAB15, member RAS oncogene family 2 4
MIRT493632 HIC2 HIC ZBTB transcriptional repressor 2 2 2
MIRT500026 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501075 SMAD7 SMAD family member 7 2 8
MIRT503094 BTG2 BTG anti-proliferation factor 2 2 4
MIRT503336 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT505465 STMN1 stathmin 1 2 4
MIRT505726 SERTAD3 SERTA domain containing 3 2 4
MIRT509333 MS4A4A membrane spanning 4-domains A4A 2 2
MIRT509978 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 4
MIRT513068 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT513446 EMP1 epithelial membrane protein 1 2 6
MIRT513736 PSD3 pleckstrin and Sec7 domain containing 3 2 4
MIRT513996 CENPQ centromere protein Q 2 4
MIRT516538 MIXL1 Mix paired-like homeobox 2 2
MIRT517606 SAV1 salvador family WW domain containing protein 1 2 2
MIRT518064 CEP89 centrosomal protein 89 2 2
MIRT518119 RNMTL1 mitochondrial rRNA methyltransferase 3 2 2
MIRT518325 WDR92 WD repeat domain 92 2 2
MIRT519048 ABCB11 ATP binding cassette subfamily B member 11 2 2
MIRT520972 SPPL2A signal peptide peptidase like 2A 2 4
MIRT521359 RPL35A ribosomal protein L35a 2 2
MIRT523359 GTF3C6 general transcription factor IIIC subunit 6 2 2
MIRT523801 FAM63A MINDY lysine 48 deubiquitinase 1 2 2
MIRT524622 C7orf73 short transmembrane mitochondrial protein 1 2 2
MIRT525550 PHB2 prohibitin 2 2 4
MIRT529709 ZBTB49 zinc finger and BTB domain containing 49 2 2
MIRT531605 PLEKHA6 pleckstrin homology domain containing A6 2 2
MIRT532387 UMPS uridine monophosphate synthetase 2 2
MIRT534468 SCD stearoyl-CoA desaturase 2 4
MIRT537546 ETNK1 ethanolamine kinase 1 2 2
MIRT541619 C11orf31 selenoprotein H 2 2
MIRT548380 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 4
MIRT549523 HDDC2 HD domain containing 2 2 2
MIRT549774 SOD2 superoxide dismutase 2 2 2
MIRT550578 SLC2A5 solute carrier family 2 member 5 2 2
MIRT551498 CENPN centromere protein N 2 4
MIRT552301 ITGA3 integrin subunit alpha 3 2 2
MIRT555400 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT556399 LUC7L LUC7 like 2 2
MIRT557047 HOXB3 homeobox B3 2 2
MIRT558072 ERO1L endoplasmic reticulum oxidoreductase 1 alpha 1 2
MIRT559659 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT561239 ZNF354B zinc finger protein 354B 2 2
MIRT566899 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT568786 FAM120B family with sequence similarity 120B 2 2
MIRT574014 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT574885 Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 2 2
MIRT575243 Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 2 2
MIRT576194 Vsig2 V-set and immunoglobulin domain containing 2 2 2
MIRT576309 Acbd7 acyl-Coenzyme A binding domain containing 7 2 2
MIRT576484 Lhx4 LIM homeobox protein 4 2 3
MIRT576646 Mill2 MHC I like leukocyte 2 1 1
MIRT576708 Kras Kirsten rat sarcoma viral oncogene homolog 2 2
MIRT576855 Socs6 suppressor of cytokine signaling 6 2 2
MIRT576950 Aldoa aldolase A, fructose-bisphosphate 2 2
MIRT617133 ZNF556 zinc finger protein 556 2 4
MIRT617928 ZNF783 zinc finger family member 783 2 2
MIRT618981 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT621100 SIX3 SIX homeobox 3 2 2
MIRT624537 BROX BRO1 domain and CAAX motif containing 2 2
MIRT625663 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT627059 DCTN6 dynactin subunit 6 2 2
MIRT628319 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT630859 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 2
MIRT632295 TMEM65 transmembrane protein 65 2 2
MIRT634115 ZNF207 zinc finger protein 207 2 2
MIRT634736 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT635655 NDST3 N-deacetylase and N-sulfotransferase 3 2 2
MIRT635772 PDCL3 phosducin like 3 2 2
MIRT635911 LILRA2 leukocyte immunoglobulin like receptor A2 2 2
MIRT636365 OGFRL1 opioid growth factor receptor like 1 2 4
MIRT637251 GLRX2 glutaredoxin 2 2 2
MIRT638705 FZD4 frizzled class receptor 4 2 2
MIRT639640 PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 2 2
MIRT639676 PPEF2 protein phosphatase with EF-hand domain 2 2 4
MIRT642267 SMIM17 small integral membrane protein 17 2 2
MIRT642372 ZNF581 zinc finger protein 581 2 2
MIRT643545 SLC25A17 solute carrier family 25 member 17 2 2
MIRT647994 PDE12 phosphodiesterase 12 2 2
MIRT649094 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT650993 ZNF770 zinc finger protein 770 2 2
MIRT651956 UBE2N ubiquitin conjugating enzyme E2 N 2 2
MIRT652977 SUN2 Sad1 and UNC84 domain containing 2 2 2
MIRT654389 RBM12B RNA binding motif protein 12B 2 2
MIRT655637 OLFML2A olfactomedin like 2A 2 2
MIRT655729 NRXN3 neurexin 3 2 2
MIRT658171 FCHSD1 FCH and double SH3 domains 1 2 2
MIRT660937 ACOX1 acyl-CoA oxidase 1 2 2
MIRT662112 CERKL ceramide kinase like 2 2
MIRT662302 MPV17L MPV17 mitochondrial inner membrane protein like 2 2
MIRT662993 TMEM59 transmembrane protein 59 2 2
MIRT663071 SFR1 SWI5 dependent homologous recombination repair protein 1 2 2
MIRT663704 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663864 MUC20 mucin 20, cell surface associated 2 2
MIRT665185 HAUS5 HAUS augmin like complex subunit 5 2 4
MIRT665402 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT665688 TNPO3 transportin 3 2 2
MIRT665795 TMEM170A transmembrane protein 170A 2 2
MIRT665847 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT666999 PDPN podoplanin 2 2
MIRT667598 LIPC lipase C, hepatic type 2 2
MIRT668576 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 4
MIRT670960 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT671187 ZNF891 zinc finger protein 891 2 2
MIRT671739 ZNF451 zinc finger protein 451 2 2
MIRT672745 ZNF585B zinc finger protein 585B 2 4
MIRT673446 ZNF583 zinc finger protein 583 2 2
MIRT679843 GPR75 G protein-coupled receptor 75 2 2
MIRT680556 ZNF584 zinc finger protein 584 2 2
MIRT680661 C1orf210 chromosome 1 open reading frame 210 2 2
MIRT681285 RFC2 replication factor C subunit 2 2 2
MIRT683264 ZNF329 zinc finger protein 329 2 2
MIRT684519 C1orf174 chromosome 1 open reading frame 174 2 2
MIRT685065 GEMIN4 gem nuclear organelle associated protein 4 2 2
MIRT685157 DTWD2 DTW domain containing 2 2 2
MIRT685168 ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit 2 2
MIRT685470 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT686001 NEK4 NIMA related kinase 4 2 2
MIRT687027 RNF24 ring finger protein 24 2 2
MIRT687543 MOB1B MOB kinase activator 1B 2 2
MIRT687592 MANEAL mannosidase endo-alpha like 2 2
MIRT687753 KIAA1328 KIAA1328 2 2
MIRT688050 GLUL glutamate-ammonia ligase 2 2
MIRT688374 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 2 2
MIRT688802 CBFA2T3 CBFA2/RUNX1 translocation partner 3 2 2
MIRT688957 ATXN3 ataxin 3 2 2
MIRT689281 C5AR2 complement component 5a receptor 2 2 2
MIRT689988 NNMT nicotinamide N-methyltransferase 2 2
MIRT689997 MMP17 matrix metallopeptidase 17 2 2
MIRT690014 LUZP2 leucine zipper protein 2 2 2
MIRT690161 ELP3 elongator acetyltransferase complex subunit 3 2 2
MIRT690379 ZSWIM7 zinc finger SWIM-type containing 7 2 2
MIRT690563 MICA MHC class I polypeptide-related sequence A 2 2
MIRT691891 EVC EvC ciliary complex subunit 1 2 2
MIRT693107 SCNM1 sodium channel modifier 1 2 2
MIRT693832 ZFP64 ZFP64 zinc finger protein 2 2
MIRT694105 ZNF446 zinc finger protein 446 2 2
MIRT694179 ZNF486 zinc finger protein 486 2 2
MIRT694475 LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2 2
MIRT694998 GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 2 2
MIRT695031 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT695163 TCTN2 tectonic family member 2 2 2
MIRT695525 SLC25A34 solute carrier family 25 member 34 2 2
MIRT696067 ZNF264 zinc finger protein 264 2 2
MIRT696616 CRIPT CXXC repeat containing interactor of PDZ3 domain 2 2
MIRT696661 AGXT2 alanine--glyoxylate aminotransferase 2 2 2
MIRT696705 PNPO pyridoxamine 5'-phosphate oxidase 2 2
MIRT697173 INMT indolethylamine N-methyltransferase 2 2
MIRT697303 ZNF652 zinc finger protein 652 2 2
MIRT697491 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT698657 TERF2 telomeric repeat binding factor 2 2 2
MIRT699042 SOAT1 sterol O-acyltransferase 1 2 2
MIRT699185 SLX4IP SLX4 interacting protein 2 2
MIRT699598 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 2
MIRT700150 RNF115 ring finger protein 115 2 2
MIRT700720 PNO1 partner of NOB1 homolog 2 2
MIRT700870 PER2 period circadian clock 2 2 2
MIRT700912 PDXK pyridoxal kinase 2 2
MIRT701095 PAPOLG poly(A) polymerase gamma 2 2
MIRT701194 OTUD3 OTU deubiquitinase 3 2 2
MIRT702203 LPP LIM domain containing preferred translocation partner in lipoma 2 2
MIRT702272 LHX4 LIM homeobox 4 2 3
MIRT703125 GPRC5A G protein-coupled receptor class C group 5 member A 2 2
MIRT703252 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT703262 GNL3L G protein nucleolar 3 like 2 2
MIRT703440 FYTTD1 forty-two-three domain containing 1 2 2
MIRT704321 DCUN1D5 defective in cullin neddylation 1 domain containing 5 2 2
MIRT704393 CTSS cathepsin S 2 2
MIRT704483 CPT1A carnitine palmitoyltransferase 1A 2 2
MIRT704880 CCSER2 coiled-coil serine rich protein 2 2 2
MIRT704926 CCDC36 coiled-coil domain containing 36 2 2
MIRT705175 BZW1 basic leucine zipper and W2 domains 1 2 2
MIRT706561 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 2 2
MIRT707048 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT711497 PGD phosphogluconate dehydrogenase 2 2
MIRT716644 EPGN epithelial mitogen 2 2
MIRT720083 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT722288 PMPCA peptidase, mitochondrial processing alpha subunit 2 2
MIRT725468 GRAP2 GRB2-related adaptor protein 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4433a Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4433a Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-mir-4433a Vincristine 5978 approved resistant cell line (W1)
hsa-mir-4433a Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4433a-3p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4433a-3p Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-4433a-3p Cisplatin 5460033 NSC119875 approved resistant High Pancreatic Cancer cell line (BxPC-3)
hsa-miR-4433a-3p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4433a-3p Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia tissue
hsa-miR-4433a-3p Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CIS)
hsa-miR-4433a-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (mitochondrial RNA)
hsa-miR-4433a-3p Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-4433a-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-4433a-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-4433a-3p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4433a-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4433a-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)

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